| Year |
Citation |
Score |
| 2024 |
Mason BJ, Estey D, Roberts A, de Guglielmo G, George O, Light J, Stoolmiller M, Quello S, Skinner M, Shadan F, Begovic A, Kyle MC, Harris RA. A reverse translational study of PPAR-α agonist efficacy in human and rodent models relevant to alcohol use disorder. Neurobiology of Stress. 29: 100604. PMID 38292518 DOI: 10.1016/j.ynstr.2023.100604 |
0.319 |
|
| 2023 |
Grantham EK, Tiwari GR, Ponomereva O, Harris RA, Lopez MF, Becker HC, Mayfield RD. Transcriptome changes in the nucleus of the solitary tract induced by repeated stress, alcohol dependence, or stress-induced drinking in dependent mice. Neuropharmacology. 109768. PMID 37865137 DOI: 10.1016/j.neuropharm.2023.109768 |
0.391 |
|
| 2022 |
Arias HR, Borghese CM, Germann AL, Pierce SR, Bonardi A, Nocentini A, Gratteri P, Thodati TM, Lim NJ, Harris RA, Akk G. (+)-Catharanthine potentiates the GABA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop. Biochemical Pharmacology. 199: 114993. PMID 35304861 DOI: 10.1016/j.bcp.2022.114993 |
0.704 |
|
| 2021 |
Kisby BR, Farris SP, McManus MM, Varodayan FP, Roberto M, Harris RA, Ponomarev I. Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala. Brain Sciences. 11. PMID 34573170 DOI: 10.3390/brainsci11091149 |
0.812 |
|
| 2021 |
Borghese CM, Wang HL, McHardy SF, Messing RO, Trudell JR, Harris RA, Bertaccini EJ. Modulation of α1β3γ2 GABA receptors expressed in oocytes using a propofol photoswitch tethered to the transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33593898 DOI: 10.1073/pnas.2008178118 |
0.737 |
|
| 2020 |
Blednov YA, Borghese CM, Dugan MP, Pradhan S, Thodati TM, Kichili NR, Harris RA, Messing RO. Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling. Neuropharmacology. 108220. PMID 32736086 DOI: 10.1016/J.Neuropharm.2020.108220 |
0.766 |
|
| 2020 |
Grantham EK, Warden AS, McCarthy GS, DaCosta A, Mason S, Blednov Y, Mayfield RD, Harris RA. Role of TLR7 in voluntary alcohol consumption. Brain, Behavior, and Immunity. PMID 32726684 DOI: 10.1016/J.Bbi.2020.07.029 |
0.76 |
|
| 2020 |
Warden AS, Wolfe SA, Khom S, Varodayan FP, Patel RR, Steinman MQ, Bajo M, Montgomery SE, Vlkolinsky R, Nadav T, Polis I, Roberts AJ, Mayfield RD, Harris RA, Roberto M. Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers. Biological Psychiatry. PMID 32680583 DOI: 10.1016/J.Biopsych.2020.05.011 |
0.339 |
|
| 2020 |
Warden AS, DaCosta A, Mason S, Blednov YA, Mayfield RD, Harris RA. Inbred Substrain Differences Influence Neuroimmune Response and Drinking Behavior. Alcoholism, Clinical and Experimental Research. PMID 32640038 DOI: 10.1111/Acer.14410 |
0.729 |
|
| 2020 |
Blednov YA, Da Costa A, Mayfield J, Harris RA, Messing RO. Deletion of Tlr3 reduces acute tolerance to alcohol and alcohol consumption in the intermittent access procedure in male mice. Addiction Biology. e12932. PMID 32604471 DOI: 10.1111/Adb.12932 |
0.477 |
|
| 2020 |
Erickson EK, DaCosta AJ, Mason SC, Blednov YA, Mayfield RD, Harris RA. Cortical astrocytes regulate ethanol consumption and intoxication in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32464636 DOI: 10.1038/S41386-020-0721-0 |
0.75 |
|
| 2020 |
Warden AS, Triplett TA, Lyu A, Grantham EK, Azzam MM, DaCosta A, Mason S, Blednov YA, Ehrlich LIR, Mayfield RD, Harris RA. Microglia depletion and alcohol: Transcriptome and behavioral profiles. Addiction Biology. e12889. PMID 32176824 DOI: 10.1111/Adb.12889 |
0.789 |
|
| 2019 |
Ferguson LB, Patil S, Moskowitz BA, Ponomarev I, Harris RA, Mayfield RD, Messing RO. A Pathway-Based Genomic Approach to Identify Medications: Application to Alcohol Use Disorder. Brain Sciences. 9. PMID 31888299 DOI: 10.3390/Brainsci9120381 |
0.793 |
|
| 2019 |
Erickson EK, Blednov YA, Harris RA, Mayfield RD. Glial gene networks associated with alcohol dependence. Scientific Reports. 9: 10949. PMID 31358844 DOI: 10.1038/S41598-019-47454-4 |
0.791 |
|
| 2019 |
Chung T, Harris RA. Cannabis and Alcohol: From Basic Science to Public Policy. Alcoholism, Clinical and Experimental Research. PMID 31265135 DOI: 10.1111/Acer.14144 |
0.404 |
|
| 2018 |
Erickson EK, Grantham EK, Warden AS, Harris RA. Neuroimmune signaling in alcohol use disorder. Pharmacology, Biochemistry, and Behavior. 177: 34-60. PMID 30590091 DOI: 10.1016/j.pbb.2018.12.007 |
0.312 |
|
| 2018 |
Warden AS, Azzam M, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice. Brain, Behavior, and Immunity. PMID 30550931 DOI: 10.1016/J.Bbi.2018.12.004 |
0.794 |
|
| 2018 |
Warden AS, Azzam MM, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 dynamics in female C57BL/6J mice: Regulation of alcohol intake. Brain, Behavior, and Immunity. PMID 30550930 DOI: 10.1016/J.Bbi.2018.12.006 |
0.445 |
|
| 2018 |
Mayfield RD, Harris RA. Persistence of Drug Memories: Melting Transcriptomes. Biological Psychiatry. 84: 860-861. PMID 30466505 DOI: 10.1016/J.Biopsych.2018.09.023 |
0.682 |
|
| 2018 |
Wolfe SA, Farris SP, Mayfield JE, Heaney CF, Erickson EK, Harris RA, Mayfield RD, Raab-Graham KF. Ethanol and a rapid-acting antidepressant produce overlapping changes in exon expression in the synaptic transcriptome. Neuropharmacology. PMID 30419244 DOI: 10.1016/J.Neuropharm.2018.11.007 |
0.756 |
|
| 2018 |
Ferguson LB, Zhang L, Wang S, Bridges C, Harris RA, Ponomarev I. Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver. Frontiers in Molecular Neuroscience. 11: 331. PMID 30283300 DOI: 10.3389/Fnmol.2018.00331 |
0.59 |
|
| 2018 |
Ferguson LB, Zhang L, Kircher D, Wang S, Mayfield RD, Crabbe JC, Morrisett RA, Harris RA, Ponomarev I. Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach. Molecular Neurobiology. PMID 30062672 DOI: 10.1007/S12035-018-1252-0 |
0.835 |
|
| 2018 |
Most D, Salem NA, Tiwari GR, Blednov YA, Mayfield RD, Harris RA. Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice. Addiction Biology. PMID 29665166 DOI: 10.1111/Adb.12625 |
0.784 |
|
| 2018 |
Ferguson LB, Harris RA, Mayfield RD. From gene networks to drugs: systems pharmacology approaches for AUD. Psychopharmacology. PMID 29497781 DOI: 10.1007/S00213-018-4855-2 |
0.747 |
|
| 2018 |
Blednov YA, Da Costa AJ, Tarbox T, Ponomareva O, Messing RO, Harris RA. Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Ethanol Consumption and Preference. Alcoholism, Clinical and Experimental Research. PMID 29469962 DOI: 10.1111/Acer.13616 |
0.368 |
|
| 2018 |
Blednov YA, Da Costa AJ, Harris RA, Messing RO. Apremilast Alters Behavioral Responses to Ethanol in Mice: II. Increased Sedation, Intoxication and Reduced Acute Functional Tolerance. Alcoholism, Clinical and Experimental Research. PMID 29469954 DOI: 10.1111/Acer.13615 |
0.378 |
|
| 2018 |
Osterndorff-Kahanek EA, Tiwari GR, Lopez MF, Becker HC, Harris RA, Mayfield RD. Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain. Plos One. 13: e0190841. PMID 29315347 DOI: 10.1371/Journal.Pone.0190841 |
0.748 |
|
| 2018 |
Erickson EK, Farris SP, Blednov YA, Mayfield RD, Harris RA. Astrocyte-specific transcriptome responses to chronic ethanol consumption. The Pharmacogenomics Journal. PMID 29305589 DOI: 10.1038/S41397-017-0012-2 |
0.812 |
|
| 2017 |
Ferguson LB, Ozburn AR, Ponomarev I, Metten P, Reilly M, Crabbe JC, Harris RA, Mayfield RD. Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29251283 DOI: 10.1038/Npp.2017.301 |
0.82 |
|
| 2017 |
McCarthy GM, Farris SP, Blednov YA, Harris RA, Mayfield RD. Microglial-specific transcriptome changes following chronic alcohol consumption. Neuropharmacology. PMID 29101021 DOI: 10.1016/J.Neuropharm.2017.10.035 |
0.838 |
|
| 2017 |
Tarvin RD, Borghese CM, Sachs W, Santos JC, Lu Y, O'Connell LA, Cannatella DC, Harris RA, Zakon HH. Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance. Science (New York, N.Y.). 357: 1261-1266. PMID 28935799 DOI: 10.1126/Science.Aan5061 |
0.739 |
|
| 2017 |
McCracken LM, Lowes DC, Salling MC, Carreau-Vollmer C, Odean NN, Blednov YA, Betz H, Harris RA, Harrison NL. Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784756 DOI: 10.1073/Pnas.1703839114 |
0.58 |
|
| 2017 |
Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Scientific Reports. 7: 6230. PMID 28740086 DOI: 10.1038/S41598-017-05966-X |
0.792 |
|
| 2017 |
Harris RA, Koob GF. The future is now: A 2020 view of alcoholism research. Neuropharmacology. 122: 1-2. PMID 28633760 DOI: 10.1016/J.Neuropharm.2017.06.001 |
0.402 |
|
| 2017 |
Blednov YA, Borghese CM, Ruiz CI, Cullins MA, Da Costa A, Osterndorff-Kahanek EA, Homanics GE, Harris RA. Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination. Neuropharmacology. PMID 28623169 DOI: 10.1016/J.Neuropharm.2017.06.013 |
0.797 |
|
| 2017 |
Ponomarev I, Stelly CE, Morikawa H, Blednov YA, Mayfield RD, Harris RA. Mechanistic insights into epigenetic modulation of ethanol consumption. Alcohol (Fayetteville, N.Y.). PMID 28433417 DOI: 10.1016/J.Alcohol.2017.01.016 |
0.811 |
|
| 2017 |
Blednov YA, Black M, Benavidez JM, Da Costa A, Mayfield J, Harris RA. Sedative and Motor Incoordination Effects of Ethanol in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28160299 DOI: 10.1111/Acer.13314 |
0.393 |
|
| 2017 |
Blednov YA, Black M, Chernis J, Da Costa A, Mayfield J, Harris RA. Ethanol Consumption in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28146272 DOI: 10.1111/Acer.13316 |
0.458 |
|
| 2017 |
Mayfield J, Harris RA. The Neuroimmune Basis of Excessive Alcohol Consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 376. PMID 27909320 DOI: 10.1038/npp.2016.177 |
0.33 |
|
| 2017 |
Warden AS, DaCosta A, Blednov YA, Mayfield RD, Harris RA. TLR3 activation increases voluntary alcohol consumption Alcohol. 60: 242. DOI: 10.1016/J.Alcohol.2017.02.348 |
0.774 |
|
| 2017 |
Harris RA, Warden AS, Mayfield RD, Blednov YA. Neuroimmune regulation of alcohol consumption Alcohol. 60: 220-221. DOI: 10.1016/J.Alcohol.2017.02.259 |
0.781 |
|
| 2017 |
Farris SP, Iancu O, Hitzemann R, Grant K, Walter NAR, Harris RA, Mayfield RD. Integrative analysis of human and non-human primate brain tissue for alcohol consumption Alcohol. 60: 213. DOI: 10.1016/J.Alcohol.2017.02.227 |
0.801 |
|
| 2016 |
Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt J, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, et al. Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986929 DOI: 10.1523/Jneurosci.2002-16.2016 |
0.778 |
|
| 2016 |
Warden A, Erickson E, Robinson G, Harris RA, Mayfield RD. The neuroimmune transcriptome and alcohol dependence: potential for targeted therapies. Pharmacogenomics. PMID 27918243 DOI: 10.2217/Pgs-2016-0062 |
0.793 |
|
| 2016 |
Tulisiak CT, Harris RA, Ponomarev I. DNA modifications in models of alcohol use disorders. Alcohol (Fayetteville, N.Y.). PMID 27865607 DOI: 10.1016/J.Alcohol.2016.11.004 |
0.612 |
|
| 2016 |
Truitt JM, Blednov YA, Benavidez JM, Black M, Ponomareva O, Law J, Merriman M, Horani S, Jameson K, Lasek AW, Harris RA, Mayfield RD. Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice. Eneuro. 3. PMID 27822501 DOI: 10.1523/ENEURO.0256-16.2016 |
0.77 |
|
| 2016 |
Wolfe SA, Workman ER, Heaney CF, Niere F, Namjoshi S, Cacheaux LP, Farris SP, Drew MR, Zemelman BV, Harris RA, Raab-Graham KF. FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties. Nature Communications. 7: 12867. PMID 27666021 DOI: 10.1038/Ncomms12867 |
0.772 |
|
| 2016 |
McCracken ML, Gorini G, McCracken LM, Mayfield RD, Harris RA, Trudell JR. Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor. Frontiers in Molecular Neuroscience. 9: 45. PMID 27378846 DOI: 10.3389/Fnmol.2016.00045 |
0.812 |
|
| 2016 |
Warden A, Truitt J, Merriman M, Ponomareva O, Jameson K, Ferguson LB, Mayfield RD, Harris RA. Localization of PPAR isotypes in the adult mouse and human brain. Scientific Reports. 6: 27618. PMID 27283430 DOI: 10.1038/Srep27618 |
0.733 |
|
| 2016 |
Mayfield J, Arends MA, Harris RA, Blednov YA. Genes and Alcohol Consumption: Studies with Mutant Mice. International Review of Neurobiology. 126: 293-355. PMID 27055617 DOI: 10.1016/Bs.Irn.2016.02.014 |
0.385 |
|
| 2016 |
Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice. Alcoholism, Clinical and Experimental Research. PMID 26857685 DOI: 10.1111/Acer.12976 |
0.367 |
|
| 2016 |
Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. Alcoholism, Clinical and Experimental Research. PMID 26857541 DOI: 10.1111/Acer.12972 |
0.469 |
|
| 2016 |
Trudell JR, Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAaRho1 Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2311 |
0.506 |
|
| 2015 |
Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Trudell JR, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience. PMID 26571107 DOI: 10.1021/Acschemneuro.5B00246 |
0.804 |
|
| 2015 |
Marballi K, Genabai NK, Blednov YA, Harris RA, Ponomarev I. Alcohol consumption induces global gene expression changes in VTA dopaminergic neurons. Genes, Brain, and Behavior. PMID 26482798 DOI: 10.1111/Gbb.12266 |
0.621 |
|
| 2015 |
Mayfield J, Blednov YA, Harris RA. Behavioral and Genetic Evidence for GIRK Channels in the CNS: Role in Physiology, Pathophysiology, and Drug Addiction. International Review of Neurobiology. 123: 279-313. PMID 26422988 DOI: 10.1016/Bs.Irn.2015.05.016 |
0.301 |
|
| 2015 |
Kim YD, Lee KM, Hwang SL, Chang HW, Kim KJ, Harris RA, Choi HS, Choi WS, Lee SE, Park CS. Inhibition of cereblon by fenofibrate ameliorates alcoholic liver disease by enhancing AMPK. Biochimica Et Biophysica Acta. PMID 26410577 DOI: 10.1016/J.Bbadis.2015.09.014 |
0.338 |
|
| 2015 |
Most D, Leiter C, Blednov YA, Harris RA, Mayfield RD. Synaptic microRNAs Coordinately Regulate Synaptic mRNAs: Perturbation by Chronic Alcohol Consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26105134 DOI: 10.1038/Npp.2015.179 |
0.781 |
|
| 2015 |
Cui C, Noronha A, Warren KR, Koob GF, Sinha R, Thakkar M, Matochik J, Crews FT, Chandler LJ, Pfefferbaum A, Becker HC, Lovinger D, Everitt BJ, Egli M, Mandyam CD, ... Harris RA, et al. Brain pathways to recovery from alcohol dependence. Alcohol (Fayetteville, N.Y.). 49: 435-52. PMID 26074423 DOI: 10.1016/J.Alcohol.2015.04.006 |
0.427 |
|
| 2015 |
Farris SP, Harris RA, Ponomarev I. Epigenetic modulation of brain gene networks for cocaine and alcohol abuse. Frontiers in Neuroscience. 9: 176. PMID 26041984 DOI: 10.3389/Fnins.2015.00176 |
0.778 |
|
| 2015 |
Horani S, Stater EP, Corringer PJ, Trudell JR, Harris RA, Howard RJ. Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors. Alcoholism, Clinical and Experimental Research. 39: 962-8. PMID 25973519 DOI: 10.1111/Acer.12735 |
0.388 |
|
| 2015 |
Farris SP, Pietrzykowski AZ, Miles MF, O'Brien MA, Sanna PP, Zakhari S, Mayfield RD, Harris RA. Applying the new genomics to alcohol dependence. Alcohol (Fayetteville, N.Y.). PMID 25896098 DOI: 10.1016/J.Alcohol.2015.03.001 |
0.821 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Mayfield J, Harris RA. Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines. Neuropharmacology. 95: 309-20. PMID 25839897 DOI: 10.1016/J.Neuropharm.2015.03.015 |
0.392 |
|
| 2015 |
Osterndorff-Kahanek EA, Becker HC, Lopez MF, Farris SP, Tiwari GR, Nunez YO, Harris RA, Mayfield RD. Chronic ethanol exposure produces time- and brain region-dependent changes in gene coexpression networks. Plos One. 10: e0121522. PMID 25803291 DOI: 10.1371/Journal.Pone.0121522 |
0.798 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Harris RA. Glycine receptors containing α2 or α3 subunits regulate specific ethanol-mediated behaviors. The Journal of Pharmacology and Experimental Therapeutics. 353: 181-91. PMID 25678534 DOI: 10.1124/Jpet.114.221895 |
0.446 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Ferguson LB, Schoenhard GL, Goate AM, Edenberg HJ, Wetherill L, Hesselbrock V, Foroud T, Harris RA. Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcoholism, Clinical and Experimental Research. 39: 136-45. PMID 25516156 DOI: 10.1111/Acer.12610 |
0.51 |
|
| 2015 |
Most D, Ferguson L, Blednov Y, Mayfield RD, Harris RA. The synaptoneurosome transcriptome: a model for profiling the emolecular effects of alcohol. The Pharmacogenomics Journal. 15: 177-88. PMID 25135349 DOI: 10.1038/Tpj.2014.43 |
0.779 |
|
| 2014 |
Most D, Workman E, Harris RA. Synaptic adaptations by alcohol and drugs of abuse: changes in microRNA expression and mRNA regulation. Frontiers in Molecular Neuroscience. 7: 85. PMID 25565954 DOI: 10.3389/Fnmol.2014.00085 |
0.336 |
|
| 2014 |
Farris SP, Arasappan D, Hunicke-Smith S, Harris RA, Mayfield RD. Transcriptome organization for chronic alcohol abuse in human brain. Molecular Psychiatry. PMID 25450227 DOI: 10.1038/Mp.2014.159 |
0.834 |
|
| 2014 |
Most D, Ferguson L, Harris RA. Molecular basis of alcoholism. Handbook of Clinical Neurology. 125: 89-111. PMID 25307570 DOI: 10.1016/B978-0-444-62619-6.00006-9 |
0.473 |
|
| 2014 |
Robinson G, Most D, Ferguson LB, Mayfield J, Harris RA, Blednov YA. Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans. International Review of Neurobiology. 118: 13-39. PMID 25175860 DOI: 10.1016/B978-0-12-801284-0.00002-6 |
0.478 |
|
| 2014 |
Ferguson LB, Most D, Blednov YA, Harris RA. PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption. Neuropharmacology. 86: 397-407. PMID 25036611 DOI: 10.1016/J.Neuropharm.2014.06.024 |
0.475 |
|
| 2014 |
Blednov YA, Benavidez JM, Black M, Harris RA. Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice. Frontiers in Neuroscience. 8: 129. PMID 24904269 DOI: 10.3389/Fnins.2014.00129 |
0.444 |
|
| 2014 |
Trudell JR, Messing RO, Mayfield J, Harris RA. Alcohol dependence: molecular and behavioral evidence. Trends in Pharmacological Sciences. 35: 317-23. PMID 24865944 DOI: 10.1016/J.Tips.2014.04.009 |
0.487 |
|
| 2014 |
Bajo M, Madamba SG, Roberto M, Blednov YA, Sagi VN, Roberts E, Rice KC, Harris RA, Siggins GR. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain, Behavior, and Immunity. 40: 191-202. PMID 24675033 DOI: 10.1016/J.Bbi.2014.03.007 |
0.371 |
|
| 2014 |
Howard RJ, Trudell JR, Harris RA. Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacological Reviews. 66: 396-412. PMID 24515646 DOI: 10.1124/Pr.113.007468 |
0.361 |
|
| 2014 |
Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Johnson D, Borghese CM, Hanrahan JR, Johnston GA, Chebib M, Harris RA. GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice. Plos One. 9: e85525. PMID 24454882 DOI: 10.1371/Journal.Pone.0085525 |
0.786 |
|
| 2014 |
Lee C, Mayfield RD, Harris RA. Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. Biological Psychiatry. 75: 765-73. PMID 24209778 DOI: 10.1016/J.Biopsych.2013.08.028 |
0.804 |
|
| 2014 |
Borghese CM, Hicks JA, Lapid DJ, Trudell JR, Harris RA. GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. Journal of Neurochemistry. 128: 363-75. PMID 24117469 DOI: 10.1111/Jnc.12476 |
0.79 |
|
| 2014 |
Gorini G, Harris RA, Mayfield RD. Proteomic approaches and identification of novel therapeutic targets for alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 104-30. PMID 23900301 DOI: 10.1038/Npp.2013.182 |
0.804 |
|
| 2014 |
Marballi K, Ponomarev I, Mayfield RD, Harris RA. Alcohol and the Brain: An Epigenetic Viewpoint Neurobiology of Alcohol Dependence. 349-358. DOI: 10.1016/B978-0-12-405941-2.00017-1 |
0.798 |
|
| 2014 |
Noronha A, Cui C, Harris RA, Crabbe JC. Neurobiology of Alcohol Dependence Neurobiology of Alcohol Dependence. 1-560. |
0.556 |
|
| 2013 |
Ferguson C, McKay M, Harris RA, Homanics GE. Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation. Alcohol (Fayetteville, N.Y.). 47: 595-9. PMID 24199847 DOI: 10.1016/J.Alcohol.2013.09.043 |
0.351 |
|
| 2013 |
Nunez YO, Truitt JM, Gorini G, Ponomareva ON, Blednov YA, Harris RA, Mayfield RD. Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. Bmc Genomics. 14: 725. PMID 24148570 DOI: 10.1186/1471-2164-14-725 |
0.795 |
|
| 2013 |
Heusser SA, Howard RJ, Borghese CM, Cullins MA, Broemstrup T, Lee US, Lindahl E, Carlsson J, Harris RA. Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Molecular Pharmacology. 84: 670-8. PMID 23950219 DOI: 10.1124/Mol.113.087692 |
0.754 |
|
| 2013 |
McCracken LM, Trudell JR, McCracken ML, Harris RA. Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol. Alcoholism, Clinical and Experimental Research. 37: 2002-10. PMID 23895467 DOI: 10.1111/Acer.12192 |
0.675 |
|
| 2013 |
Lee C, Harris RA, Wall JK, Mayfield RD, Wilke CO. RNaseIII and T4 polynucleotide Kinase sequence biases and solutions during RNA-seq library construction. Biology Direct. 8: 16. PMID 23826734 DOI: 10.1186/1745-6150-8-16 |
0.698 |
|
| 2013 |
Sauguet L, Howard RJ, Malherbe L, Lee US, Corringer PJ, Harris RA, Delarue M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nature Communications. 4: 1697. PMID 23591864 DOI: 10.1038/Ncomms2682 |
0.449 |
|
| 2013 |
Osterndorff-Kahanek E, Ponomarev I, Blednov YA, Harris RA. Gene expression in brain and liver produced by three different regimens of alcohol consumption in mice: comparison with immune activation. Plos One. 8: e59870. PMID 23555817 DOI: 10.1371/Journal.Pone.0059870 |
0.655 |
|
| 2013 |
Eberhart JK, Harris RA. Understanding variability in ethanol teratogenicity. Proceedings of the National Academy of Sciences of the United States of America. 110: 5285-6. PMID 23513226 DOI: 10.1073/Pnas.1302650110 |
0.324 |
|
| 2013 |
Mayfield J, Ferguson L, Harris RA. Neuroimmune signaling: a key component of alcohol abuse. Current Opinion in Neurobiology. 23: 513-20. PMID 23434064 DOI: 10.1016/J.Conb.2013.01.024 |
0.482 |
|
| 2013 |
Ozburn AR, Harris RA, Blednov YA. Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice. Pharmacology, Biochemistry, and Behavior. 104: 33-9. PMID 23313769 DOI: 10.1016/J.Pbb.2012.12.025 |
0.755 |
|
| 2013 |
McCracken LM, Blednov YA, Trudell JR, Benavidez JM, Betz H, Harris RA. Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo. The Journal of Pharmacology and Experimental Therapeutics. 344: 489-500. PMID 23230213 DOI: 10.1124/Jpet.112.197707 |
0.653 |
|
| 2013 |
Blednov YA, Benavidez JM, Black M, Chandra D, Homanics GE, Rudolph U, Harris RA. Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication. Neuropharmacology. 67: 46-56. PMID 23147414 DOI: 10.1016/J.Neuropharm.2012.10.016 |
0.347 |
|
| 2013 |
Howard RJ, Sauguet L, Broemstrup T, Murail S, Lee US, Horani S, Trudell JR, Corringer P, Lindahl E, Delarue M, Harris RA. Alcohol and Anesthetic Binding to Pentameric Ligand-Gated Ion Channels Revealed in a Prokaryotic Model System Biophysical Journal. 104: 635a-636a. DOI: 10.1016/J.Bpj.2012.11.3512 |
0.371 |
|
| 2013 |
Sauguet L, Howard R, Malherbe L, Lee US, Corringer P, Harris RA, Delarue M. X-Ray Structures of an Interfacial Potentiating Site for Alcohols and Anesthetics in a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1175 |
0.462 |
|
| 2013 |
Harris RA, Blednov YA. Neuroimmune genes and alcohol drinking behavior Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. 425-440. DOI: 10.1007/978-1-4614-4729-0_13 |
0.319 |
|
| 2012 |
Borghese CM, Harris RA. Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice. Alcohol Research : Current Reviews. 34: 345-53. PMID 23134051 |
0.794 |
|
| 2012 |
Ozburn AR, Mayfield RD, Ponomarev I, Jones TA, Blednov YA, Harris RA. Chronic self-administration of alcohol results in elevated ΔFosB: comparison of hybrid mice with distinct drinking patterns. Bmc Neuroscience. 13: 130. PMID 23102405 DOI: 10.1186/1471-2202-13-130 |
0.835 |
|
| 2012 |
Murail S, Howard RJ, Broemstrup T, Bertaccini EJ, Harris RA, Trudell JR, Lindahl E. Molecular mechanism for the dual alcohol modulation of Cys-loop receptors. Plos Computational Biology. 8: e1002710. PMID 23055913 DOI: 10.1371/Journal.Pcbi.1002710 |
0.452 |
|
| 2012 |
Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI, Harris RA. Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology. 117: 765-71. PMID 22885675 DOI: 10.1097/Aln.0B013E31826A0D93 |
0.806 |
|
| 2012 |
Blednov YA, Mayfield RD, Belknap J, Harris RA. Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. Genes, Brain, and Behavior. 11: 424-35. PMID 22405477 DOI: 10.1111/J.1601-183X.2012.00780.X |
0.771 |
|
| 2012 |
Ponomarev I, Wang S, Zhang L, Harris RA, Mayfield RD. Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1884-97. PMID 22302827 DOI: 10.1523/Jneurosci.3136-11.2012 |
0.827 |
|
| 2012 |
Johnson WD, Howard RJ, Trudell JR, Harris RA. The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. The Journal of Pharmacology and Experimental Therapeutics. 340: 445-56. PMID 22072732 DOI: 10.1124/Jpet.111.188037 |
0.467 |
|
| 2012 |
Blednov YA, Benavidez JM, Homanics GE, Harris RA. Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. The Journal of Pharmacology and Experimental Therapeutics. 340: 317-29. PMID 22037202 DOI: 10.1124/Jpet.111.185124 |
0.393 |
|
| 2012 |
Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA. Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. The Journal of Pharmacology and Experimental Therapeutics. 340: 304-16. PMID 22037201 DOI: 10.1124/Jpet.111.185116 |
0.84 |
|
| 2012 |
Blednov YA, Ponomarev I, Geil C, Bergeson S, Koob GF, Harris RA. Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addiction Biology. 17: 108-20. PMID 21309947 DOI: 10.1111/J.1369-1600.2010.00284.X |
0.671 |
|
| 2011 |
Etheridge N, Mayfield RD, Harris RA, Dodd PR. Identifying changes in the synaptic proteome of cirrhotic alcoholic superior frontal gyrus. Current Neuropharmacology. 9: 122-8. PMID 21886576 DOI: 10.2174/157015911795017164 |
0.772 |
|
| 2011 |
Howard RJ, Murail S, Ondricek KE, Corringer PJ, Lindahl E, Trudell JR, Harris RA. Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 12149-54. PMID 21730162 DOI: 10.1073/Pnas.1104480108 |
0.495 |
|
| 2011 |
Howard RJ, Slesinger PA, Davies DL, Das J, Trudell JR, Harris RA. Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcoholism, Clinical and Experimental Research. 35: 1561-73. PMID 21676006 DOI: 10.1111/J.1530-0277.2011.01502.X |
0.452 |
|
| 2011 |
Lewohl JM, Nunez YO, Dodd PR, Tiwari GR, Harris RA, Mayfield RD. Up-regulation of microRNAs in brain of human alcoholics. Alcoholism, Clinical and Experimental Research. 35: 1928-37. PMID 21651580 DOI: 10.1111/J.1530-0277.2011.01544.X |
0.778 |
|
| 2011 |
Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Jr MC, Nixon SJ, Riley EP, Schuckit MA, Sher KJ, Thomas JD. How Should Addiction-Related Research at the National Institutes of Health be Reorganized? Frontiers in Psychiatry. 2: 2. PMID 21629835 DOI: 10.3389/Fpsyt.2011.00002 |
0.524 |
|
| 2011 |
Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Mitchell MC, Nixon SJ, Riley EP, Schuckit MA, Sher KJ, Thomas JD. Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details. Alcoholism, Clinical and Experimental Research. 35: 572-80. PMID 21443646 DOI: 10.1111/J.1530-0277.2011.01493.X |
0.562 |
|
| 2011 |
Morikawa H, Harris RA. Small K channels: big targets for treating alcoholism? Biological Psychiatry. 69: 614-5. PMID 21397742 DOI: 10.1016/J.Biopsych.2011.01.016 |
0.487 |
|
| 2011 |
Crabbe JC, Harris RA, Koob GF. Preclinical studies of alcohol binge drinking. Annals of the New York Academy of Sciences. 1216: 24-40. PMID 21272009 DOI: 10.1111/J.1749-6632.2010.05895.X |
0.611 |
|
| 2011 |
Blednov YA, Benavidez JM, Geil C, Perra S, Morikawa H, Harris RA. Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice. Brain, Behavior, and Immunity. 25: S92-S105. PMID 21266194 DOI: 10.1016/J.Bbi.2011.01.008 |
0.342 |
|
| 2011 |
Mulligan MK, Rhodes JS, Crabbe JC, Mayfield RD, Harris RA, Ponomarev I. Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 35: 659-70. PMID 21223303 DOI: 10.1111/J.1530-0277.2010.01384.X |
0.837 |
|
| 2011 |
Harris RA, Osterndorff-Kahanek E, Ponomarev I, Homanics GE, Blednov YA. Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice. Neuroscience Letters. 488: 31-5. PMID 21056629 DOI: 10.1016/J.Neulet.2010.10.075 |
0.573 |
|
| 2011 |
Blednov YA, Borghese CM, McCracken ML, Benavidez JM, Geil CR, Osterndorff-Kahanek E, Werner DF, Iyer S, Swihart A, Harrison NL, Homanics GE, Harris RA. Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. The Journal of Pharmacology and Experimental Therapeutics. 336: 145-54. PMID 20876231 DOI: 10.1124/Jpet.110.171645 |
0.363 |
|
| 2011 |
Howard RJ, Ondricek KE, Trudell JR, Harris RA. Structural Basis for Alcohol Modulation of a Ligand-Gated Ion Channel Homolog Biophysical Journal. 100: 101a. DOI: 10.1016/J.Bpj.2010.12.756 |
0.492 |
|
| 2011 |
Borghese CM, harris RA. Alcohol dependence and genes encoding α2 and γ1 GABAA receptor subunits insights from humans and mice Alcohol Research and Health. 34: 345-354. |
0.345 |
|
| 2010 |
McCracken LM, McCracken ML, Gong DH, Trudell JR, Harris RA. Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues. Acs Chemical Neuroscience. 1: 482. PMID 21326622 DOI: 10.1021/cn100019g |
0.563 |
|
| 2010 |
Lee C, Mayfield RD, Harris RA. Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. Plos One. 5: e14044. PMID 21124972 DOI: 10.1371/Journal.Pone.0014044 |
0.749 |
|
| 2010 |
McCracken ML, Borghese CM, Trudell JR, Harris RA. A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 335: 600-6. PMID 20826568 DOI: 10.1124/Jpet.110.170472 |
0.806 |
|
| 2010 |
Ozburn AR, Harris RA, Blednov YA. Behavioral differences between C57BL/6J x FVB/NJ and C57BL/6J x NZB/B1NJ F1 hybrid mice: relation to control of ethanol intake. Behavior Genetics. 40: 551-63. PMID 20364436 DOI: 10.1007/S10519-010-9357-X |
0.707 |
|
| 2010 |
Ponomarev I, Rau V, Eger EI, Harris RA, Fanselow MS. Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1402-11. PMID 20147889 DOI: 10.1038/Npp.2010.10 |
0.543 |
|
| 2010 |
Gorini G, Ponomareva O, Shores KS, Person MD, Harris RA, Mayfield RD. Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes. Febs Letters. 584: 845-51. PMID 20114047 DOI: 10.1016/J.Febslet.2009.12.061 |
0.759 |
|
| 2010 |
McCracken LM, Trudell JR, Goldstein BE, Harris RA, Mihic SJ. Zinc enhances ethanol modulation of the alpha1 glycine receptor. Neuropharmacology. 58: 676-81. PMID 19913039 DOI: 10.1016/J.Neuropharm.2009.11.001 |
0.834 |
|
| 2010 |
Blednov YA, Ozburn AR, Walker D, Ahmed S, Belknap JK, Harris RA. Hybrid mice as genetic models of high alcohol consumption. Behavior Genetics. 40: 93-110. PMID 19798565 DOI: 10.1007/S10519-009-9298-4 |
0.724 |
|
| 2009 |
Etheridge N, Lewohl JM, Mayfield RD, Harris RA, Dodd PR. Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain. Proteomics. Clinical Applications. 3: 730-742. PMID 19924264 DOI: 10.1002/Prca.200800202 |
0.784 |
|
| 2009 |
Mayfield RD, Harris RA. Gene expression profiling in blood: new diagnostics in alcoholism and addiction? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 250-1. PMID 19079075 DOI: 10.1038/Npp.2008.162 |
0.767 |
|
| 2008 |
Horishita T, Eger EI, Harris RA. The effects of volatile aromatic anesthetics on voltage-gated Na+ channels expressed in Xenopus oocytes. Anesthesia and Analgesia. 107: 1579-86. PMID 18931215 DOI: 10.1213/Ane.0B013E318184B966 |
0.318 |
|
| 2008 |
Jenkins A, Lobo IA, Gong D, Trudell JR, Solt K, Harris RA, Eger EI. General anesthetics have additive actions on three ligand gated ion channels. Anesthesia and Analgesia. 107: 486-93. PMID 18633027 DOI: 10.1213/Ane.0B013E31817B70C1 |
0.797 |
|
| 2008 |
Harris RA, Trudell JR, Mihic SJ. Ethanol's molecular targets. Science Signaling. 1: re7. PMID 18632551 DOI: 10.1126/Scisignal.128Re7 |
0.697 |
|
| 2008 |
Ozburn AR, Harris RA, Blednov YA. Wheel running, voluntary ethanol consumption, and hedonic substitution. Alcohol (Fayetteville, N.Y.). 42: 417-24. PMID 18579336 DOI: 10.1016/J.Alcohol.2008.04.006 |
0.725 |
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| 2008 |
Horishita T, Harris RA. n-Alcohols inhibit voltage-gated Na+ channels expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 326: 270-7. PMID 18434586 DOI: 10.1124/Jpet.108.138370 |
0.429 |
|
| 2008 |
Lobo IA, Harris RA. GABA(A) receptors and alcohol. Pharmacology, Biochemistry, and Behavior. 90: 90-4. PMID 18423561 DOI: 10.1016/J.Pbb.2008.03.006 |
0.851 |
|
| 2008 |
Blednov YA, Harris RA. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 775-93. PMID 18377703 DOI: 10.1017/S1461145708008584 |
0.491 |
|
| 2008 |
Mayfield RD, Harris RA, Schuckit MA. Genetic factors influencing alcohol dependence. British Journal of Pharmacology. 154: 275-87. PMID 18362899 DOI: 10.1038/Bjp.2008.88 |
0.75 |
|
| 2008 |
Reilly MT, Lobo IA, McCracken LM, Borghese CM, Gong D, Horishita T, Harris RA. Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 32: 188-96. PMID 18226119 DOI: 10.1111/J.1530-0277.2007.00569.X |
0.81 |
|
| 2008 |
Lobo IA, Harris RA, Trudell JR. Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation. Journal of Neurochemistry. 104: 1649-62. PMID 18036150 DOI: 10.1111/J.1471-4159.2007.05090.X |
0.816 |
|
| 2007 |
Okvist A, Johansson S, Kuzmin A, Bazov I, Merino-Martinez R, Ponomarev I, Mayfield RD, Harris RA, Sheedy D, Garrick T, Harper C, Hurd YL, Terenius L, Ekström TJ, Bakalkin G, et al. Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. Plos One. 2: e930. PMID 17895971 DOI: 10.1371/Journal.Pone.0000930 |
0.805 |
|
| 2007 |
Liu J, Lewohl JM, Harris RA, Dodd PR, Mayfield RD. Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics. Alcoholism, Clinical and Experimental Research. 31: 1460-6. PMID 17625000 DOI: 10.1111/J.1530-0277.2007.00444.X |
0.82 |
|
| 2007 |
Borghese CM, Harris RA. Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol (Fayetteville, N.Y.). 41: 155-62. PMID 17521845 DOI: 10.1016/J.Alcohol.2007.03.006 |
0.796 |
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| 2007 |
Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI, Homanics GE. Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane. Anesthesiology. 106: 107-13. PMID 17197852 DOI: 10.1097/00000542-200701000-00019 |
0.345 |
|
| 2007 |
Blednov YA, Cravatt BF, Boehm SL, Walker D, Harris RA. Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1570-82. PMID 17164820 DOI: 10.1038/Sj.Npp.1301274 |
0.722 |
|
| 2007 |
Maiya R, Ponomarev I, Linse KD, Harris RA, Mayfield RD. Defining the dopamine transporter proteome by convergent biochemical and in silico analyses. Genes, Brain, and Behavior. 6: 97-106. PMID 16643512 DOI: 10.1111/J.1601-183X.2006.00236.X |
0.767 |
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| 2006 |
Blednov YA, Walker D, Martinez M, Harris RA. Reduced alcohol consumption in mice lacking preprodynorphin. Alcohol (Fayetteville, N.Y.). 40: 73-86. PMID 17307643 DOI: 10.1016/J.Alcohol.2006.12.002 |
0.477 |
|
| 2006 |
Boehm SL, Ponomarev I, Blednov YA, Harris RA. From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions. Advances in Pharmacology (San Diego, Calif.). 54: 171-203. PMID 17175815 DOI: 10.1016/S1054-3589(06)54008-6 |
0.799 |
|
| 2006 |
Crabbe JC, Phillips TJ, Harris RA, Arends MA, Koob GF. Alcohol-related genes: contributions from studies with genetically engineered mice. Addiction Biology. 11: 195-269. PMID 16961758 DOI: 10.1111/J.1369-1600.2006.00038.X |
0.681 |
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| 2006 |
Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J. Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry. 63: 957-68. PMID 16952998 DOI: 10.1001/Archpsyc.63.9.957 |
0.468 |
|
| 2006 |
Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL. An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 208-18. PMID 16807363 DOI: 10.1124/Jpet.106.104406 |
0.689 |
|
| 2006 |
Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319: 219-27. PMID 16785315 DOI: 10.1124/Jpet.106.106161 |
0.796 |
|
| 2006 |
Boehm SL, Homanics GE, Blednov YA, Harris RA. delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol. European Journal of Pharmacology. 541: 158-62. PMID 16777089 DOI: 10.1016/J.Ejphar.2006.02.054 |
0.687 |
|
| 2006 |
Ponomarev I, Maiya R, Harnett MT, Schafer GL, Ryabinin AE, Blednov YA, Morikawa H, Boehm SL, Homanics GE, Berman AE, Berman A, Lodowski KH, Bergeson SE, Harris RA. Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5673-83. PMID 16723524 DOI: 10.1523/Jneurosci.0860-06.2006 |
0.802 |
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| 2006 |
Won A, Oh I, Liao M, Sonner JM, Harris RA, Laster MJ, Brosnan R, Trudell JR, Eger EI. The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms. Anesthesia and Analgesia. 102: 1419-26. PMID 16632820 DOI: 10.1213/01.Ane.0000204258.00676.98 |
0.372 |
|
| 2006 |
Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA. Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 318: 434-43. PMID 16622040 DOI: 10.1124/Jpet.106.101691 |
0.397 |
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| 2006 |
Mulligan MK, Ponomarev I, Hitzemann RJ, Belknap JK, Tabakoff B, Harris RA, Crabbe JC, Blednov YA, Grahame NJ, Phillips TJ, Finn DA, Hoffman PL, Iyer VR, Koob GF, Bergeson SE. Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proceedings of the National Academy of Sciences of the United States of America. 103: 6368-73. PMID 16618939 DOI: 10.1073/Pnas.0510188103 |
0.832 |
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| 2006 |
Jung S, Harris RA. Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors. Journal of Neurochemistry. 96: 885-92. PMID 16405501 DOI: 10.1111/J.1471-4159.2005.03617.X |
0.712 |
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| 2006 |
Liu J, Lewohl JM, Harris RA, Iyer VR, Dodd PR, Randall PK, Mayfield RD. Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1574-82. PMID 16292326 DOI: 10.1038/Sj.Npp.1300947 |
0.822 |
|
| 2006 |
Borghese CM, Stórustovu SÃ, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA. The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 316: 1360-8. PMID 16272217 DOI: 10.1124/Jpet.105.092452 |
0.755 |
|
| 2006 |
Lobo IA, Trudell JR, Harris RA. Accessibility to residues in transmembrane segment four of the glycine receptor. Neuropharmacology. 50: 174-81. PMID 16225893 DOI: 10.1016/J.Neuropharm.2005.08.017 |
0.823 |
|
| 2006 |
Dodd PR, Tannenberg RK, Buckley ST, Eckert AL, Innes DJ, Mayfield RD, Harris RA. Interactions between serotonergic genotype and amino acid transmitter receptor expression in human alcoholics Alcoholism: Clinical and Experimental Research. 30. DOI: 10.1111/J.1530-0277.2006.00197.X |
0.8 |
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| 2006 |
Boehm SL, Ponomarev I, Blednov YA, Harris RA. From Gene to Behavior and Back Again: New Perspectives on GABAA Receptor Subunit Selectivity of Alcohol Actions1 Advances in Pharmacology. 54: 171-203. DOI: 10.1016/S1054-3589(06)54008-6 |
0.773 |
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| 2005 |
Blednov YA, Metten P, Finn DA, Rhodes JS, Bergeson SE, Harris RA, Crabbe JC. Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 29: 1949-58. PMID 16340451 DOI: 10.1097/01.Alc.0000187605.91468.17 |
0.553 |
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| 2005 |
Dani JA, Harris RA. Nicotine addiction and comorbidity with alcohol abuse and mental illness. Nature Neuroscience. 8: 1465-70. PMID 16251989 DOI: 10.1038/Nn1580 |
0.3 |
|
| 2005 |
Hara K, Yamakura T, Sata T, Harris RA. The effects of anesthetics and ethanol on α2 adrenoceptor subtypes expressed with G protein-coupled inwardly rectifying potassium channels in Xenopus oocytes Anesthesia & Analgesia. 101: 1381-1388. PMID 16243998 DOI: 10.1213/01.Ane.0000180190.05238.D5 |
0.304 |
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| 2005 |
Lobo IA, Harris RA. Sites of alcohol and volatile anesthetic action on glycine receptors. International Review of Neurobiology. 65: 53-87. PMID 16140053 DOI: 10.1016/S0074-7742(04)65003-3 |
0.83 |
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| 2005 |
Blednov YA, Bergeson SE, Walker D, Ferreira VM, Kuziel WA, Harris RA. Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol. Behavioural Brain Research. 165: 110-25. PMID 16105698 DOI: 10.1016/J.Bbr.2005.06.026 |
0.449 |
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| 2005 |
Alling C, Chick JD, Anton R, Mayfield RD, Salaspuro M, Helander A, Harris RA. Revealing alcohol abuse: to ask or to test? Alcoholism, Clinical and Experimental Research. 29: 1257-63. PMID 16088981 DOI: 10.1097/01.Alc.0000171489.55856.A5 |
0.742 |
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| 2005 |
Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI. Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesthesia and Analgesia. 101: 412-8, table of cont. PMID 16037154 DOI: 10.1213/01.Ane.0000154196.86587.35 |
0.759 |
|
| 2005 |
Jung S, Akabas MH, Harris RA. Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation. The Journal of Biological Chemistry. 280: 308-16. PMID 15522868 DOI: 10.1074/Jbc.M409871200 |
0.689 |
|
| 2004 |
Blednov YA, Walker D, Osterndorf-Kahanek E, Harris RA. Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol (Fayetteville, N.Y.). 34: 251-9. PMID 15902920 DOI: 10.1016/J.Alcohol.2004.10.003 |
0.403 |
|
| 2004 |
Blednov YA, Walker D, Harris RA. Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcoholism, Clinical and Experimental Research. 28: 1683-92. PMID 15547455 DOI: 10.1097/01.Alc.0000145790.60216.C8 |
0.477 |
|
| 2004 |
Ponomarev I, Schafer GL, Blednov YA, Williams RW, Iyer VR, Harris RA. Convergent analysis of cDNA and short oligomer microarrays, mouse null mutants and bioinformatics resources to study complex traits. Genes, Brain, and Behavior. 3: 360-8. PMID 15544578 DOI: 10.1111/J.1601-183X.2004.00088.X |
0.64 |
|
| 2004 |
Lewohl JM, Van Dyk DD, Craft GE, Innes DJ, Mayfield RD, Cobon G, Harris RA, Dodd PR. The application of proteomics to the human alcoholic brain. Annals of the New York Academy of Sciences. 1025: 14-26. PMID 15542695 DOI: 10.1196/Annals.1316.002 |
0.78 |
|
| 2004 |
Boehm SL, Peden L, Jennings AW, Kojima N, Harris RA, Blednov YA. Over-expression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice. Neuroscience Letters. 372: 6-11. PMID 15531078 DOI: 10.1016/J.Neulet.2004.08.028 |
0.705 |
|
| 2004 |
Boehm SL, Ponomarev I, Jennings AW, Whiting PJ, Rosahl TW, Garrett EM, Blednov YA, Harris RA. gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochemical Pharmacology. 68: 1581-602. PMID 15451402 DOI: 10.1016/J.Bcp.2004.07.023 |
0.8 |
|
| 2004 |
Liu J, Lewohl JM, Dodd PR, Randall PK, Harris RA, Mayfield RD. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. Journal of Neurochemistry. 90: 1050-8. PMID 15312160 DOI: 10.1111/J.1471-4159.2004.02570.X |
0.812 |
|
| 2004 |
Lobo IA, Trudell JR, Harris RA. Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. Journal of Neurochemistry. 90: 962-9. PMID 15287902 DOI: 10.1111/J.1471-4159.2004.02561.X |
0.806 |
|
| 2004 |
Zhang Y, Sonner JM, Eger EI, Stabernack CR, Laster MJ, Raines DE, Harris RA. Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane. Anesthesia and Analgesia. 99: 85-90. PMID 15281509 DOI: 10.1213/01.Ane.0000118108.64886.42 |
0.351 |
|
| 2004 |
Lobo IA, Mascia MP, Trudell JR, Harris RA. Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. The Journal of Biological Chemistry. 279: 33919-27. PMID 15169788 DOI: 10.1074/Jbc.M313941200 |
0.814 |
|
| 2004 |
Shiraishi M, Harris RA. Effects of Alcohols and Anesthetics on Recombinant Voltage-Gated Na+ Channels Journal of Pharmacology and Experimental Therapeutics. 309: 987-994. PMID 14978193 DOI: 10.1124/Jpet.103.064063 |
0.344 |
|
| 2004 |
Boehm SL, Peden L, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters sensitivity to GABAergic drugs: dependence on beta2/beta3 GABAA receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 309: 1154-9. PMID 14764659 DOI: 10.1124/Jpet.103.064444 |
0.688 |
|
| 2004 |
Harris RA, Mihic SJ. Alcohol and inhibitory receptors: unexpected specificity from a nonspecific drug. Proceedings of the National Academy of Sciences of the United States of America. 101: 2-3. PMID 14695895 DOI: 10.1073/pnas.0307281101 |
0.691 |
|
| 2003 |
Mayfield RD, Liu J, Randall PK, Lewohl JM, Dodd PR, Harris RA. Methods for the identification of differentially expressed genes in human post-mortem brain. Methods (San Diego, Calif.). 31: 301-5. PMID 14597314 DOI: 10.1016/S1046-2023(03)00159-2 |
0.764 |
|
| 2003 |
Borghese CM, Henderson LA, Bleck V, Trudell JR, Harris RA. Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 307: 42-52. PMID 14500778 DOI: 10.1124/Jpet.102.053710 |
0.792 |
|
| 2003 |
Borghese CM, Wang L, Bleck V, Harris RA. Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action. Addiction Biology. 8: 313-8. PMID 13129833 DOI: 10.1080/13556210310001602220 |
0.788 |
|
| 2003 |
Findlay GS, Phelan R, Roberts MT, Homanics GE, Bergeson SE, Lopreato GF, Mihic SJ, Blednov YA, Harris RA. Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8051-9. PMID 12954867 DOI: 10.1523/Jneurosci.23-22-08051.2003 |
0.752 |
|
| 2003 |
Boehm SL, Peden L, Chang R, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters behavioral sensitivity to ethanol. Alcoholism, Clinical and Experimental Research. 27: 1033-40. PMID 12878908 DOI: 10.1097/01.Alc.0000075822.80583.71 |
0.684 |
|
| 2003 |
Zhang Y, Laster MJ, Hara K, Harris RA, Eger EI, Stabernack CR, Sonner JM. Glycine receptors mediate part of the immobility produced by inhaled anesthetics. Anesthesia and Analgesia. 96: 97-101, table of con. PMID 12505932 DOI: 10.1097/00000539-200301000-00021 |
0.35 |
|
| 2003 |
Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism, Clinical and Experimental Research. 26: 1764-72. PMID 12500099 DOI: 10.1097/01.ALC.0000042012.58231.D9 |
0.777 |
|
| 2003 |
Blednov YA, Jung S, Alva H, Wallace D, Rosahl T, Whiting PJ, Harris RA. Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. The Journal of Pharmacology and Experimental Therapeutics. 304: 30-6. PMID 12490572 DOI: 10.1124/Jpet.102.042960 |
0.37 |
|
| 2002 |
Hara K, Eger EI, Laster MJ, Harris RA. Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. Anesthesiology. 97: 1512-20. PMID 12459679 DOI: 10.1097/00000542-200212000-00025 |
0.352 |
|
| 2002 |
Borghese CM, Harris RA. Anesthetic-induced immobility: Neuronal nicotinic acetylcholine receptors are no longer in the picture Anesthesia and Analgesia. 95: 509-511. PMID 12198026 |
0.706 |
|
| 2002 |
Harris RA, Morrisett RA. Two-shot cocktail: adenosine, dopamine and a twist of beta gamma. Nature Medicine. 8: 777-9. PMID 12152026 DOI: 10.1038/Nm0802-777 |
0.326 |
|
| 2002 |
Maiya R, Buck KJ, Harris RA, Mayfield RD. Ethanol-sensitive sites on the human dopamine transporter. The Journal of Biological Chemistry. 277: 30724-9. PMID 12070173 DOI: 10.1074/Jbc.M204914200 |
0.801 |
|
| 2002 |
Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA. Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. Journal of Neurochemistry. 81: 802-13. PMID 12065639 DOI: 10.1046/J.1471-4159.2002.00860.X |
0.816 |
|
| 2002 |
Findlay GS, Wick MJ, Mascia MP, Wallace D, Miller GW, Harris RA, Blednov YA. Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice. The Journal of Pharmacology and Experimental Therapeutics. 300: 526-34. PMID 11805213 DOI: 10.1124/Jpet.300.2.526 |
0.725 |
|
| 2002 |
Borghese CM, Harris RA. Anesthetic-induced immobility: neuronal nicotinic acetylcholine receptors are no longer in the picture. Anesthesia & Analgesia. 95: 509-511. DOI: 10.1213/00000539-200209000-00001 |
0.342 |
|
| 2002 |
Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism: Clinical and Experimental Research. 26: 1764-1772. DOI: 10.1111/J.1530-0277.2002.Tb02482.X |
0.434 |
|
| 2001 |
Zhang Y, Stabernack CR, Dutton R, Sonner J, Trudell JR, Mihic SJ, Yamakura T, Harris RA, Gong D, Eger EI. Luciferase as a model for the site of inhaled anesthetic action. Anesthesia and Analgesia. 93: 1246-52. PMID 11682406 DOI: 10.1097/00000539-200111000-00041 |
0.629 |
|
| 2001 |
Hara K, Lewohl JM, Yamakura T, Harris RA. Mutational analysis of ethanol interactions with G-protein-coupled inwardly rectifying potassium channels. Alcohol. 24: 5-8. PMID 11524176 DOI: 10.1016/S0741-8329(01)00134-3 |
0.342 |
|
| 2001 |
Yamakura T, Lewohl JM, Harris RA. Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 95: 144-153. PMID 11465552 DOI: 10.1097/00000542-200107000-00025 |
0.338 |
|
| 2001 |
Ueno S, Harris RA, Messing RO, Sanchez-Perez AM, Hodge CW, McMahon T, Wang D, Mehmert KK, Kelley SP, Haywood A, Olive MF, Buck KJ, Hood HM, Blednov Y, Findlay G, et al. Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior. Alcoholism, Clinical and Experimental Research. 25: 76S-81S. PMID 11391054 DOI: 10.1111/J.1530-0277.2001.Tb02378.X |
0.737 |
|
| 2001 |
Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors. Neuroscience Letters. 305: 77-80. PMID 11356312 DOI: 10.1016/S0304-3940(01)01646-9 |
0.381 |
|
| 2001 |
Godden EL, Harris RA, Dunwiddie TV. Correlation between molecular volume and effects of n-alcohols on human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 296: 716-22. PMID 11181898 |
0.398 |
|
| 2001 |
Lewohl JM, Dodd PR, Mayfield RD, Harris RA. Application of DNA microarrays to study human alcoholism. Journal of Biomedical Science. 8: 28-36. PMID 11173973 DOI: 10.1007/Bf02255968 |
0.792 |
|
| 2000 |
Zhang Y, Trudell JR, Mascia MP, Laster MJ, Gong DH, Harris RA, Eger EI. The anesthetic potencies of alkanethiols for rats: relevance to theories of narcosis. Anesthesia and Analgesia. 91: 1294-9. PMID 11049925 DOI: 10.1213/00000539-200011000-00045 |
0.615 |
|
| 2000 |
Mascia MP, Gong DH, Eger EI, Harris RA. The anesthetic potency of propanol and butanol versus propanethiol and butanethiol in alpha1 wild type and alpha1(S267Q) glycine receptors. Anesthesia and Analgesia. 91: 1289-93. PMID 11049924 |
0.685 |
|
| 2000 |
Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected]. Neuroscience Letters. 293: 155-8. PMID 11036184 DOI: 10.1016/S0304-3940(00)01503-2 |
0.381 |
|
| 2000 |
Yamakura T, Harris RA. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels: Comparison with isoflurane and ethanol Anesthesiology. 93: 1095-1101. PMID 11020766 DOI: 10.1097/00000542-200010000-00034 |
0.327 |
|
| 2000 |
Yamakura T, Borghese C, Harris RA. A transmembrane site determines sensitivity of neuronal nicotinic acetylcholine receptors to general anesthetics. Journal of Biological Chemistry. 275: 40879-40886. PMID 11020384 DOI: 10.1074/Jbc.M005771200 |
0.324 |
|
| 2000 |
Ueno S, Lin A, Nikolaeva N, Trudell JR, Mihic SJ, Harris RA, Harrison NL. Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. British Journal of Pharmacology. 131: 296-302. PMID 10991923 DOI: 10.1038/Sj.Bjp.0703504 |
0.686 |
|
| 2000 |
Baer K, Essrich C, Balsiger S, Wick MJ, Harris RA, Fritschy JM, Lüscher B. Rescue of γ2 subunit-deficient mice by transgenic overexpression of the GABA(A) receptor γ2S or γ2L subunit isoforms European Journal of Neuroscience. 12: 2639-2643. PMID 10947838 DOI: 10.1046/J.1460-9568.2000.00159.X |
0.375 |
|
| 2000 |
Wick MJ, Radcliffe RA, Bowers BJ, Mascia MP, Lüscher B, Harris RA, Wehner JM. Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor. The European Journal of Neuroscience. 12: 2634-8. PMID 10947837 DOI: 10.1046/J.1460-9568.2000.00160.X |
0.756 |
|
| 2000 |
Mascia MP, Trudell JR, Harris RA. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 9305-10. PMID 10908659 DOI: 10.1073/Pnas.160128797 |
0.745 |
|
| 2000 |
Yamakura T, Chavez-Noriega LE, Harris RA. Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine. Anesthesiology. 92: 1144-1153. PMID 10754635 DOI: 10.1097/00000542-200004000-00033 |
0.356 |
|
| 2000 |
Mascia MP, Gong DH, Eger EI, Harris RA. The Anesthetic Potency of Propanol and Butanol Versus Propanethiol and Butanethiol in α1 Wild Type and α1(s267q) Glycine Receptors Anesthesia & Analgesia. 91: 1289-1293. DOI: 10.1213/00000539-200011000-00044 |
0.714 |
|
| 2000 |
Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA. Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex Alcoholism: Clinical and Experimental Research. 24: 1873-1882. DOI: 10.1111/J.1530-0277.2000.Tb01993.X |
0.64 |
|
| 1999 |
Lewohl JM, Wilson WR, Mayfield RD, Brozowski SJ, Morrisett RA, Harris RA. G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. Nature Neuroscience. 2: 1084-90. PMID 10570485 DOI: 10.1038/16012 |
0.767 |
|
| 1999 |
Yamakura T, Mihic SJ, Harris RA. Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors. The Journal of Biological Chemistry. 274: 23006-12. PMID 10438467 DOI: 10.1074/Jbc.274.33.23006 |
0.644 |
|
| 1999 |
Ueno S, Wick MJ, Ye Q, Harrison NL, Harris RA. Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes. British Journal of Pharmacology. 127: 377-82. PMID 10385236 DOI: 10.1038/Sj.Bjp.0702563 |
0.403 |
|
| 1999 |
Cardoso RA, Brozowski SJ, Chavez-Noriega LE, Harpold M, Valenzuela CF, Harris RA. Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 289: 774-80. PMID 10215652 |
0.362 |
|
| 1999 |
Ueno S, Trudell JR, Eger EI, Harris RA. Actions of fluorinated alkanols on GABA(A) receptors: relevance to theories of narcosis. Anesthesia and Analgesia. 88: 877-83. PMID 10195541 DOI: 10.1097/00000539-199904000-00036 |
0.324 |
|
| 1999 |
Ueno S, Trudell JR, Eger EI, Harris RA. Actions of Fluorinated Alkanols on GABAA Receptors Anesthesia & Analgesia. 88: 877-883. DOI: 10.1213/00000539-199904000-00036 |
0.32 |
|
| 1999 |
Harris RA. Ethanol Actions on Multiple Ion Channels: Which Are Important? Alcoholism: Clinical and Experimental Research. 23: 1563-1570. DOI: 10.1111/J.1530-0277.1999.Tb04045.X |
0.401 |
|
| 1998 |
Chandler LJ, Harris RA, Crews FT. Ethanol tolerance and synaptic plasticity. Trends in Pharmacological Sciences. 19: 491-5. PMID 9871410 DOI: 10.1016/S0165-6147(98)01268-1 |
0.385 |
|
| 1998 |
Mascia MP, Wick MJ, Martinez LD, Harris RA. Enhancement of glycine receptor function by ethanol: role of phosphorylation. British Journal of Pharmacology. 125: 263-70. PMID 9786497 DOI: 10.1038/Sj.Bjp.0702054 |
0.728 |
|
| 1998 |
Valenzuela CF, Bhave S, Hoffman P, Harris RA. Acute effects of ethanol on pharmacologically isolated kainate receptors in cerebellar granule neurons: comparison with NMDA and AMPA receptors. Journal of Neurochemistry. 71: 1777-80. PMID 9751216 DOI: 10.1046/J.1471-4159.1998.71041777.X |
0.383 |
|
| 1998 |
Valenzuela CF, Cardoso RA, Wick MJ, Weiner JL, Dunwiddie TV, Harris RA. Effects of ethanol on recombinant glycine receptors expressed in mammalian cell lines. Alcoholism, Clinical and Experimental Research. 22: 1132-6. PMID 9726286 DOI: 10.1111/J.1530-0277.1998.Tb03712.X |
0.395 |
|
| 1998 |
Harris RA, Mihic SJ, Valenzuela CF. Alcohol and benzodiazepines: recent mechanistic studies. Drug and Alcohol Dependence. 51: 155-64. PMID 9716937 DOI: 10.1016/S0376-8716(98)00073-8 |
0.628 |
|
| 1998 |
Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA. Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proceedings of the National Academy of Sciences of the United States of America. 95: 6504-9. PMID 9600996 DOI: 10.1073/Pnas.95.11.6504 |
0.83 |
|
| 1998 |
Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. The Journal of Biological Chemistry. 273: 3314-9. PMID 9452448 DOI: 10.1074/Jbc.273.6.3314 |
0.826 |
|
| 1998 |
Minami K, Gereau RW, Minami M, Heinemann SF, Harris RA. Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes. Molecular Pharmacology. 53: 148-56. PMID 9443943 DOI: 10.1124/Mol.53.1.148 |
0.382 |
|
| 1998 |
Harris RA, Valenzuela CF, Brozowski S, Chuang L, Hadingham K, Whiting PJ. Adaptation of gamma-aminobutyric acid type A receptors to alcohol exposure: studies with stably transfected cells. The Journal of Pharmacology and Experimental Therapeutics. 284: 180-8. PMID 9435176 |
0.311 |
|
| 1997 |
Mihic SJ, Harris RA. GABA and the GABAA receptor. Alcohol Health and Research World. 21: 127-31. PMID 15704348 |
0.706 |
|
| 1997 |
Minami K, Vanderah TW, Minami M, Harris RA. Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes. European Journal of Pharmacology. 339: 237-44. PMID 9473141 DOI: 10.1016/S0014-2999(97)01354-X |
0.364 |
|
| 1997 |
Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389: 385-9. PMID 9311780 DOI: 10.1038/38738 |
0.823 |
|
| 1997 |
Minami K, Minami M, Harris RA. Inhibition of 5-hydroxytryptamine type 2A receptor-induced currents by n-alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 281: 1136-43. PMID 9190846 |
0.327 |
|
| 1997 |
Harris RA, Mihic SJ, Brozowski S, Hadingham K, Whiting PJ. Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 21: 444-51. PMID 9161604 |
0.632 |
|
| 1997 |
Mascia MP, Bleck VG, Harris RA. Glycine receptors from long-sleep and short-sleep mice: genetic differences in drug sensitivity. Brain Research. Molecular Brain Research. 45: 169-72. PMID 9105687 DOI: 10.1016/S0169-328X(97)00008-9 |
0.679 |
|
| 1996 |
Harris RA. Transfected cells for study of alcohol actions on GABAA receptors Addiction Biology. 1: 157-163. PMID 12893475 DOI: 10.1080/1355621961000124776 |
0.446 |
|
| 1996 |
Mascia MP, Machu TK, Harris RA. Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics. British Journal of Pharmacology. 119: 1331-6. PMID 8968539 DOI: 10.1111/j.1476-5381.1996.tb16042.x |
0.743 |
|
| 1996 |
Blednov YA, Bleck V, Harris RA. Measurement of glycine receptor function by radioactive chloride uptake Journal of Neuroscience Methods. 68: 253-257. PMID 8912198 DOI: 10.1016/0165-0270(96)00088-X |
0.34 |
|
| 1996 |
Dildy-Mayfield JE, Mihic SJ, Liu Y, Deitrich RA, Harris RA. Actions of long chain alcohols on GABAA and glutamate receptors: relation to in vivo effects. British Journal of Pharmacology. 118: 378-84. PMID 8735641 |
0.704 |
|
| 1996 |
Mihic SJ, Harris RA. Robotic automation of Xenopus oocyte bath perfusion. Biotechniques. 20: 802-4. PMID 8723922 |
0.523 |
|
| 1996 |
Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Molecular Pharmacology. 50: 402-6. PMID 8700149 |
0.781 |
|
| 1996 |
Deitrich RA, Harris RA. How much alcohol should I use in my experiments? Alcoholism: Clinical and Experimental Research. 20: 1-2. PMID 8651438 DOI: 10.1111/j.1530-0277.1996.tb01033.x |
0.301 |
|
| 1996 |
Mihic SJ, Harris RA. Inhibition of rho1 receptor GABAergic currents by alcohols and volatile anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 277: 411-6. PMID 8613949 |
0.667 |
|
| 1995 |
Klein RL, Mascia MP, Whiting PJ, Harris RA. GABAA receptor function and binding in stably transfected cells: chronic ethanol treatment. Alcoholism, Clinical and Experimental Research. 19: 1338-44. PMID 8561312 DOI: 10.1111/J.1530-0277.1995.Tb01622.X |
0.734 |
|
| 1995 |
Sanna E, Garau F, Harris RA. Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital. Molecular Pharmacology. 47: 213-7. PMID 7870027 |
0.53 |
|
| 1995 |
Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV. Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcoholism, Clinical and Experimental Research. 19: 226-32. PMID 7771653 DOI: 10.1111/J.1530-0277.1995.Tb01496.X |
0.734 |
|
| 1995 |
Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, Wehner JM. Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors. Proceedings of the National Academy of Sciences of the United States of America. 92: 3658-62. PMID 7731960 DOI: 10.1073/Pnas.92.9.3658 |
0.3 |
|
| 1995 |
Mihic SJ, Sanna E, Whiting PJ, Harris RA. Pharmacology of recombinant GABAA receptors. Advances in Biochemical Psychopharmacology. 48: 17-40. PMID 7653324 |
0.715 |
|
| 1995 |
Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA. Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 274: 353-60. PMID 7616420 |
0.759 |
|
| 1995 |
Harris RA, Mihic SJ, Dildy-Mayfield JE, Machu TK. Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1454-62. PMID 7589987 DOI: 10.1096/fasebj.9.14.7589987 |
0.622 |
|
| 1995 |
Klein RL, Mascia MP, Harkness PC, Hadingham KL, Whiting PJ, Harris RA. Regulation of allosteric coupling and function of stably expressed gamma-aminobutyric acid (GABA)A receptors by chronic treatment with GABAA and benzodiazepine agonists. The Journal of Pharmacology and Experimental Therapeutics. 274: 1484-92. PMID 7562525 |
0.695 |
|
| 1994 |
Avdulov NA, Wood WG, Harris RA. Effects of ethanol on structural parameters of rat brain membranes: relationship to genetic differences in ethanol sensitivity. Alcoholism: Clinical and Experimental Research. 18: 53-59. PMID 8198227 DOI: 10.1111/J.1530-0277.1994.Tb00880.X |
0.338 |
|
| 1994 |
Sanna E, Dildy-Mayfield JE, Harris RA. Ethanol inhibits the function of 5-hydroxytryptamine type 1c and muscarinic M1 G protein-linked receptors in Xenopus oocytes expressing brain mRNA: role of protein kinase C. Molecular Pharmacology. 45: 1004-12. PMID 8190090 |
0.55 |
|
| 1994 |
Mihic SJ, Whatley VJ, McQuilkin SJ, Harris RA. beta-Lumicolchicine interacts with the benzodiazepine binding site to potentiate GABAA receptor-mediated currents. Journal of Neurochemistry. 62: 1790-4. PMID 8158128 |
0.614 |
|
| 1994 |
Mihic SJ, McQuilkin SJ, Eger EI, Ionescu P, Harris RA. Potentiation of gamma-aminobutyric acid type A receptor-mediated chloride currents by novel halogenated compounds correlates with their abilities to induce general anesthesia. Molecular Pharmacology. 46: 851-7. PMID 7969071 |
0.622 |
|
| 1994 |
Klein RL, Sanna E, McQuilkin SJ, Whiting PJ, Harris RA. Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABAA receptors. European Journal of Pharmacology. 268: 237-46. PMID 7957645 DOI: 10.1016/0922-4106(94)90194-5 |
0.537 |
|
| 1994 |
Mihic SJ, Whiting PJ, Harris RA. Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity. European Journal of Pharmacology. 268: 209-14. PMID 7957642 DOI: 10.1016/0922-4106(94)90190-2 |
0.65 |
|
| 1994 |
Whatley VJ, Mihic SJ, Allan AM, McQuilkin SJ, Harris RA. Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization. The Journal of Biological Chemistry. 269: 19546-52. PMID 7913471 |
0.638 |
|
| 1994 |
Mihic SJ, Whiting PJ, Klein RL, Wafford KA, Harris RA. A single amino acid of the human gamma-aminobutyric acid type A receptor gamma 2 subunit determines benzodiazepine efficacy. The Journal of Biological Chemistry. 269: 32768-73. PMID 7806498 |
0.643 |
|
| 1993 |
Sanna E, Harris RA. Recent developments in alcoholism:neuronal ion channels. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 11: 169-86. PMID 7694329 |
0.533 |
|
| 1993 |
Lin L‐, Whiting P, Harris RA. Molecular determinants of general anesthetic action: role of GABAA receptor structure. Journal of Neurochemistry. 60: 1548-1553. PMID 7681105 DOI: 10.1111/J.1471-4159.1993.Tb03320.X |
0.389 |
|
| 1992 |
Harris RA, Brodie MS, Dunwiddie TV. Possible substrates of ethanol reinforcement: GABA and dopamine. Annals of the New York Academy of Sciences. 654: 61-9. PMID 1321582 DOI: 10.1111/J.1749-6632.1992.Tb25956.X |
0.325 |
|
| 1992 |
Samson HH, Harris RA. Neurobiology of alcohol abuse. Trends in Pharmacological Sciences. 13: 206-11. PMID 1306042 DOI: 10.1016/0165-6147(92)90065-E |
0.483 |
|
| 1991 |
Harris RA. Mammalian Genetics in the Study of Alcohol and Anesthetic Actions Annals of the New York Academy of Sciences. 625: 508-514. PMID 2058902 DOI: 10.1111/J.1749-6632.1991.Tb33881.X |
0.359 |
|
| 1991 |
Daniell LC, Harris RA. Effect of Chronic Ethanol Treatment and Selective Breeding for Sensitivity to Ethanol on Calcium Release Induced by Inositol Trisphosphate for Ethanol from Brain and Liver Microsomes Alcoholism: Clinical and Experimental Research. 15: 224-228. PMID 2058799 DOI: 10.1111/J.1530-0277.1991.Tb01860.X |
0.328 |
|
| 1991 |
Buck KJ, Harris RA. Neuroadaptive responses to chronic ethanol. Alcoholism, Clinical and Experimental Research. 15: 460-70. PMID 1715134 DOI: 10.1111/J.1530-0277.1991.Tb00544.X |
0.392 |
|
| 1991 |
Wafford KA, Burnett DM, Leidenheimer NJ, Burt DR, Wang JB, Kofuji P, Dunwiddie TV, Harris RA, Sikela JM. Ethanol sensitivity of the GABAA receptor expressed in Xenopus oocytes requires 8 amino acids contained in the gamma 2L subunit. Neuron. 7: 27-33. PMID 1712603 DOI: 10.1016/0896-6273(91)90071-7 |
0.364 |
|
| 1991 |
Buck KJ, McQuilkin SJ, Harris RA. Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 2100-5. PMID 1658234 DOI: 10.1111/J.1471-4159.1991.Tb06428.X |
0.403 |
|
| 1991 |
Buck KJ, Hahner L, Sikela J, Harris RA. Chronic ethanol treatment alters brain levels of gamma-aminobutyric acidA receptor subunit mRNAs: relationship to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 1452-5. PMID 1654394 DOI: 10.1111/J.1471-4159.1991.Tb08313.X |
0.385 |
|
| 1991 |
Allan AM, Burnett D, Harris RA. Ethanol-induced changes in chloride flux are mediated by both GABA(A) and GABA(B) receptors Alcoholism: Clinical and Experimental Research. 15: 233-237. PMID 1647705 DOI: 10.1111/J.1530-0277.1991.Tb01862.X |
0.388 |
|
| 1991 |
Buck KJ, Heim H, Harris RA. Reversal of alcohol dependence and tolerance by a single administration of flumazenil. The Journal of Pharmacology and Experimental Therapeutics. 257: 984-9. PMID 1646333 |
0.314 |
|
| 1990 |
Harris RA. Alcohol sensitivity [6] Nature. 348: 589. PMID 2174513 |
0.323 |
|
| 1990 |
Buck KJ, Harris RA. Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 253: 713-9. PMID 2160008 |
0.305 |
|
| 1990 |
Harris RA. Distinct actions of alcohols, barbiturates and benzodiazepines on GABA-activated chloride channels Alcohol. 7: 273-275. PMID 1691915 DOI: 10.1016/0741-8329(90)90017-7 |
0.415 |
|
| 1990 |
McQuilkin SJ, Harris RA. Factors affecting actions of ethanol on GABA-activated chloride channels Life Sciences. 46: 527-541. PMID 1689450 DOI: 10.1016/0024-3205(90)90009-G |
0.369 |
|
| 1989 |
Buck KJ, Allan AM, Harris RA. Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx. European Journal of Pharmacology. 160: 359-67. PMID 2714367 DOI: 10.1016/0014-2999(89)90091-5 |
0.403 |
|
| 1989 |
Lewin E, Peris J, Bleck V, Zahniser NR, Harris RA. Diazepam sensitizes mice to FG 7142 and reduces muscimol-stimulated 36Cl- flux. Pharmacology, Biochemistry, and Behavior. 33: 465-8. PMID 2479037 DOI: 10.1016/0091-3057(89)90531-5 |
0.326 |
|
| 1988 |
Feller DJ, Harris RA, Crabbe JC. Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice. European Journal of Pharmacology. 157: 147-54. PMID 3224635 DOI: 10.1016/0014-2999(88)90377-9 |
0.556 |
|
| 1988 |
Harris RA, Allan AM. Neurochemistry of brain chloride channels: genetic variation in modulation by GABA agonists, alcohol and benzodiazepines Advances in Biochemical Psychopharmacology. 45: 189-198. PMID 2459919 |
0.313 |
|
| 1988 |
Allan AM, Gallaher EJ, Gionet SE, Harris RA. Genetic selection for benzodiazepine ataxia produces functional changes in the γ-aminobutyric acid receptor chloride channel complex Brain Research. 452: 118-126. PMID 2456824 DOI: 10.1016/0006-8993(88)90016-9 |
0.379 |
|
| 1988 |
Daniell LC, Harris RA. Effect of chronic ethanol treatment and selective breeding for hypnotic sensitivity to ethanol on intracellular ionized calcium concentrations in synaptosomes. Alcoholism: Clinical and Experimental Research. 12: 179-183. PMID 2450482 DOI: 10.1111/J.1530-0277.1988.Tb00156.X |
0.359 |
|
| 1987 |
Allan AM, Huidobro-Toro JP, Bleck V, Harris RA. Alcohol and the GABA receptor-chloride channel complex of brain Alcohol and Alcoholism. 643-646. PMID 2447905 |
0.342 |
|
| 1986 |
Allan AM, Harris RA. Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice Life Sciences. 39: 2005-2015. PMID 3784767 DOI: 10.1016/0024-3205(86)90324-3 |
0.395 |
|
| 1985 |
Bylund DB, Solomon N, Ray-Prenger C, Jones SB, Harris RA. Comparison of adrenergic receptor binding in blood cells from alcoholics and controls. Alcohol (Fayetteville, N.Y.). 1: 369-72. PMID 6537222 DOI: 10.1016/0741-8329(84)90005-3 |
0.372 |
|
| 1985 |
Mitchell MA, Peris J, Harris RA. Barbiturate tolerance and dependence: effects on synaptosomal sodium transport and membrane fluidity. Pharmacology, Biochemistry, and Behavior. 22: 955-60. PMID 4040639 DOI: 10.1016/0091-3057(85)90302-8 |
0.319 |
|
| 1984 |
Harris RA, Crabbe JC, McSwigan JD. Relationship of membrane physical properties to alcohol dependence in mice selected for genetic differences in alcohol withdrawal. Life Sciences. 35: 2601-8. PMID 6542619 DOI: 10.1016/0024-3205(84)90027-4 |
0.55 |
|
| 1983 |
Yamamoto HA, Harris RA. Calcium-dependent 86Rb efflux and ethanol intoxication: Studies of human red blood cells and rodent brain synaptosomes European Journal of Pharmacology. 88: 357-363. PMID 6861876 DOI: 10.1016/0014-2999(83)90586-1 |
0.32 |
|
| 1983 |
Harris RA, Fenner D, Feller D, Sieckman G, Lloyd S, Mitchell M, Dexter JD, Tumbelson ME, Bylund DB. Neurochemical effects of long-term ingestion of ethanol by Sinclair (S-1) swine. Pharmacology, Biochemistry, and Behavior. 18: 363-7. PMID 6132410 DOI: 10.1016/0091-3057(83)90455-0 |
0.376 |
|
| 1982 |
Rohde BH, Harris RA. GABA and flunitrazepam binding to neuroblastoma cell membranes--effects of growth conditions, ethanol and pentobarbital. Brain Research. 253: 133-141. PMID 6129916 DOI: 10.1016/0006-8993(82)90680-1 |
0.333 |
|
| 1980 |
Snell D, Harris RA. Impairment of avoidance behavior following short-term ingestion of ethanol, tertiary-butanol, or pentobarbital in mice. Psychopharmacology. 69: 53-57. PMID 6771827 DOI: 10.1007/Bf00426521 |
0.345 |
|
| 1979 |
Harris RA, Krause W, Goh E, Case J. Behavioral and biochemical effects of chronic consumption of ethanol by hamsters. Pharmacology, Biochemistry, and Behavior. 10: 343-7. PMID 572060 DOI: 10.1016/0091-3057(79)90195-3 |
0.331 |
|
| 1979 |
Harris RA, Wu YC, Loh HH. Brain sulfatide and non-lipid sulfate metabolism in leucodystrophic (jimpy) mice. Research Communications in Chemical Pathology and Pharmacology. 25: 377-88. PMID 493721 |
0.369 |
|
| 1979 |
Harris RA, Loh HH. Brain sulfatide and non-lipid sulfate metabolism in hypothyroid rats. Research Communications in Chemical Pathology and Pharmacology. 24: 169-79. PMID 432433 |
0.336 |
|
| 1979 |
Snell D, Harris RA. Impairment of avoidance behavior following short-term ingestion of alcohol. Psychopharmacology. 63: 251-7. PMID 113811 DOI: 10.1007/BF00433558 |
0.303 |
|
| 1979 |
Harris RA, Snell D, Loh HH. Effects of chronic d-amphetamine treatment on schedule-controlled behavior. Psychopharmacology. 63: 55-61. PMID 112622 DOI: 10.1007/Bf00426922 |
0.353 |
|
| 1978 |
Huidobro-Toro JP, Harris RA, Loh HH, Way EL. Effects of hypothyroidism on the response of the rat colon to morphine. European Journal of Pharmacology. 52: 191-5. PMID 729631 DOI: 10.1016/0014-2999(78)90205-4 |
0.514 |
|
| 1978 |
Iwamoto ET, Harris RA, Loh HH, Way EL. Antinociceptive responses after microinjection of morphine or lanthanum in discrete rat brain sites. The Journal of Pharmacology and Experimental Therapeutics. 206: 46-55. PMID 660557 |
0.524 |
|
| 1978 |
Harris RA, Snell D, Loh HH. Effects of d-amphetamine, monomethoxyamphetamines and hallucinogens on schedule-controlled behavior. The Journal of Pharmacology and Experimental Therapeutics. 204: 103-17. PMID 619124 |
0.341 |
|
| 1978 |
Yamamoto H, Harris RA, Loh HH, Way EL. Effects of acute and chronic morphine treatments on calcium localization and binding in brain. The Journal of Pharmacology and Experimental Therapeutics. 205: 255-64. PMID 565404 |
0.532 |
|
| 1978 |
Law PY, Harris RA, Loh HH, Way EL. Evidence for the involvement of cerebroside sulfate in opiate receptor binding: Studies with Azure A and jimpy mutant mice. The Journal of Pharmacology and Experimental Therapeutics. 207: 458-68. PMID 213557 |
0.562 |
|
| 1977 |
Harris RA, Snell D, Loh HH. Stereoselective effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) on schedule-controlled behavior. Pharmacology, Biochemistry, and Behavior. 7: 307-10. PMID 928488 DOI: 10.1016/0091-3057(77)90225-8 |
0.329 |
|
| 1977 |
Harris RA, Snell D, Loh HH, Way EL. Behavioral interactions between naloxone and dopamine agonists. European Journal of Pharmacology. 43: 243-6. PMID 872878 DOI: 10.1016/0014-2999(77)90023-1 |
0.524 |
|
| 1977 |
Harris RA, Yamamoto H, Loh HH, Way EL. Discrete changes in brain calcium with morphine analgesia, tolerance-dependence, and abstinence. Life Sciences. 20: 501-5. PMID 557160 DOI: 10.1016/0024-3205(77)90393-9 |
0.529 |
|
| 1977 |
Loh HH, Lee NM, Harris RA. Alterations of macromolecule biosynthesis after chronic administration of opiates and ethanol. Advances in Experimental Medicine and Biology. 85: 65-86. PMID 339683 |
0.456 |
|
| 1977 |
Yamamoto H, Harris RA, Loh HH, Way EL. Effects of morphine tolerance and dependence on Mg++ dependent ATPase activity of synaptic vesicles. Life Sciences. 20: 1533-9. PMID 141578 DOI: 10.1016/0024-3205(77)90445-3 |
0.531 |
|
| 1976 |
Yamamoto HA, Harris RA, Loh HH, Way EL. Calcium binding to brain membranes: effects of morphine tolerance. Proceedings of the Western Pharmacology Society. 19: 71-4. PMID 996029 |
0.526 |
|
| 1976 |
Harris RA, Loh HH, Way EL. Alterations in the efficacy of naloxone induced by stress, cyclic adenosine monophosphate, and morphine tolerance. European Journal of Pharmacology. 39: 1-10. PMID 183962 DOI: 10.1016/0014-2999(76)90107-2 |
0.529 |
|
| 1976 |
Harris RA, Loh HH, Way EL. Antinociceptive effects of lanthanum and cerium in nontolerant and morphine tolerant-dependent animals. The Journal of Pharmacology and Experimental Therapeutics. 196: 288-97. PMID 176345 |
0.544 |
|
| 1975 |
Harris RA, Loh HH, Way EL. Effects of divalent cations, cation chelators and an ionophore on morphine analgesia and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 195: 488-98. PMID 1195132 |
0.532 |
|
| 1975 |
Harris RA, Iwamoto ET, Loh HH, Way EL. Analgetic effects of lanthanum: cross-tolerance with morphine. Brain Research. 100: 221-5. PMID 1182518 DOI: 10.1016/0006-8993(75)90264-4 |
0.502 |
|
| 1975 |
Harris RA, Iwamoto ET, Loh HH, Way EL. Site dependent analgesia after microinjection of morphine or lanthanum in rat brain. Proceedings of the Western Pharmacology Society. 18: 275-8. PMID 1178680 |
0.525 |
|
| 1975 |
Loh HH, Cho TM, Wu YC, Harris RA, Way EL. Opiate binding to cerebroside sulfate: a model system for opiate-receptor interaction. Life Sciences. 16: 1811-7. PMID 1152609 DOI: 10.1016/0024-3205(75)90281-7 |
0.579 |
|
| 1975 |
Harris RA, Harris LS, Dunn A. Effect of narcotic drugs on ribonucleic acid and nucleotide metabolism in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 192: 280-7. PMID 1117416 |
0.411 |
|
| 1974 |
Kosersky DS, Harris RA, Harris LS. Naloxone-precipitated jumping activity in mice following the acute administration of morphine. European Journal of Pharmacology. 26: 122-4. PMID 4857602 DOI: 10.1016/0014-2999(74)90084-3 |
0.409 |
|
| 1974 |
Harris RA, Dunn A, Harris LS. Effects of acute and chronic morphine administration on the incorporation of (3H)-lysine into mouse brain and liver proteins. Research Communications in Chemical Pathology and Pharmacology. 9: 299-306. PMID 4438835 |
0.414 |
|
| 1972 |
McMillan DE, Ford RD, Frankenheim JM, Harris RA, Harris LS. Tolerance to active constituents of marihuana. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 132-44. PMID 5053235 |
0.369 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Blednov YA, Bajo M, Roberts AJ, Da Costa AJ, Black M, Edmunds S, Mayfield J, Roberto M, Homanics GE, Lasek AW, Hitzemann RJ, Harris RA. Scn4b regulates the hypnotic effects of ethanol and other sedative drugs. Genes, Brain, and Behavior. e12562. PMID 30817077 DOI: 10.1111/Gbb.12562 |
0.299 |
|
| 1982 |
Harris RA, Fenner D. [Ethanol and synaptosomal calcium binding]. Biochemical Pharmacology. 31: 1790-2. PMID 7104042 DOI: 10.1016/0006-2952(82)90688-8 |
0.298 |
|
| 2013 |
Brömstrup T, Howard RJ, Trudell JR, Harris RA, Lindahl E. Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites. Structure (London, England : 1993). 21: 1307-16. PMID 23891290 DOI: 10.1016/J.Str.2013.06.018 |
0.295 |
|
| 1990 |
Wafford KA, Burnett DM, Dunwiddie TV, Harris RA. Genetic differences in the ethanol sensitivity of GABAA receptors expressed in Xenopus oocytes. Science (New York, N.Y.). 249: 291-3. PMID 1695761 |
0.293 |
|
| 1987 |
Harris RA, Burnett R, Mcquilkin S, Mcclard A, Simon FR. Effects of ethanol on membrane order: fluorescence studies. Annals of the New York Academy of Sciences. 492: 125-135. PMID 3474923 DOI: 10.1111/J.1749-6632.1987.Tb48660.X |
0.291 |
|
| 1983 |
Martz A, Deitrich RA, Harris RA. Behavioral evidence for the involvement of gamma-aminobutyric acid in the actions of ethanol. European Journal of Pharmacology. 89: 53-62. PMID 6861890 DOI: 10.1016/0014-2999(83)90607-6 |
0.289 |
|
| 1990 |
Buck KJ, Harris RA. Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. I. Acute effects of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 253: 706-12. PMID 2160007 |
0.289 |
|
| 1993 |
Wafford KA, Burnett D, Harris RA, Whiting PJ. GABAA receptor subunit expression and sensitivity to ethanol. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 327-30. PMID 7748319 |
0.286 |
|
| 2000 |
Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA. Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcoholism, Clinical and Experimental Research. 24: 1873-82. PMID 11141048 |
0.286 |
|
| 1984 |
Harris RA. Defining the membrane pathology produced by chronic alcohol consumption Laboratory Investigation. 50: 113-114. PMID 6694354 |
0.286 |
|
| 2017 |
McCarthy GM, Bridges CR, Blednov YA, Harris RA. CNS cell-type localization and LPS response of TLR signaling pathways. F1000research. 6: 1144. PMID 29043065 DOI: 10.12688/F1000Research.12036.1 |
0.284 |
|
| 2017 |
Kim YD, Hwang SL, Lee EJ, Kim HM, Chung MJ, Elfadl AK, Lee SE, Nedumaran B, Harris RA, Jeong KS. Melatonin ameliorates alcohol-induced bile acid synthesis by enhancing miR-497 expression. Journal of Pineal Research. PMID 28095641 DOI: 10.1111/Jpi.12386 |
0.283 |
|
| 2020 |
Lee SE, Koh H, Joo DJ, Nedumaran B, Jeon HJ, Park CS, Harris RA, Kim YD. Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway. Journal of Pineal Research. e12638. PMID 32053237 DOI: 10.1111/Jpi.12638 |
0.282 |
|
| 1999 |
Harris RA. Ethanol actions on multiple ion channels: Which are important? Alcoholism: Clinical and Experimental Research. 23: 1563-1570. PMID 10549986 |
0.281 |
|
| 2001 |
Blednov YA, Stoffel M, Chang SR, Harris RA. GIRK2 deficient mice: Evidence for hyperactivity and reduced anxiety Physiology and Behavior. 74: 109-117. PMID 11564458 DOI: 10.1016/S0031-9384(01)00555-8 |
0.28 |
|
| 2014 |
Cui C, Shurtleff D, Harris RA. Neuroimmune mechanisms of alcohol and drug addiction. International Review of Neurobiology. 118: 1-12. PMID 25175859 DOI: 10.1016/B978-0-12-801284-0.00001-4 |
0.278 |
|
| 1981 |
Harris RA, Hitzemann RJ. Membrane fluidity and alcohol actions Currents in Alcoholism. 8: 379-404. PMID 6282544 |
0.278 |
|
| 1987 |
Allan AM, Harris RA. Involvement of neuronal chloride channels in ethanol intoxication, tolerance, and dependence Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 5: 313-325. PMID 2436258 DOI: 10.1007/978-1-4899-1684-6_12 |
0.275 |
|
| 2003 |
Blednov YA, Walker D, Alva H, Creech K, Findlay G, Harris RA. GABAa receptor α1 and β2 subunit null mutant mice: Behavioral responses to ethanol Journal of Pharmacology and Experimental Therapeutics. 305: 854-863. PMID 12626647 DOI: 10.1124/Jpet.103.049478 |
0.274 |
|
| 1979 |
Harris RA. Alteration of alcohol effects by calcium and other inorganic cations. Pharmacology, Biochemistry, and Behavior. 10: 527-34. PMID 111265 DOI: 10.1016/0091-3057(79)90228-4 |
0.273 |
|
| 1989 |
Allan AM, Harris RA. A new alcohol antagonist: Phaclofen Life Sciences. 45: 1771-1779. PMID 2556616 DOI: 10.1016/0024-3205(89)90516-X |
0.273 |
|
| 2008 |
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, Harris RA. Intrathecal veratridine administration increases minimum alveolar concentration in rats. Anesthesia and Analgesia. 107: 875-8. PMID 18713899 DOI: 10.1213/Ane.0B013E3181815Fbc |
0.271 |
|
| 2011 |
Werner DF, Swihart A, Rau V, Jia F, Borghese CM, McCracken ML, Iyer S, Fanselow MS, Oh I, Sonner JM, Eger EI, Harrison NL, Harris RA, Homanics GE. Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane. The Journal of Pharmacology and Experimental Therapeutics. 336: 134-44. PMID 20807777 DOI: 10.1124/Jpet.110.170431 |
0.269 |
|
| 1981 |
Harris RA, Hood WF. Inhibition of synaptosomal calcium uptake by ethanol. The Journal of Pharmacology and Experimental Therapeutics. 213: 562-8. PMID 7193727 |
0.269 |
|
| 2009 |
Blednov YA, Harris RA. Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol. Neuropharmacology. 56: 814-20. PMID 19705551 DOI: 10.1016/J.Neuropharm.2009.01.007 |
0.269 |
|
| 1988 |
Harris RA, Allan AM, Daniell LC, Nixon C. Antagonism of ethanol and pentobarbital actions by benzodiazepine inverse agonists: Neurochemical studies Journal of Pharmacology and Experimental Therapeutics. 247: 1012-1017. PMID 2849653 |
0.266 |
|
| 1987 |
Allan AM, Harris RA. Acute and chronic ethanol treatments alter GABA receptor-operated chloride channels Pharmacology, Biochemistry and Behavior. 27: 665-670. PMID 2443933 DOI: 10.1016/0091-3057(87)90192-4 |
0.263 |
|
| 1985 |
Harris RA, Bruno P. Membrane disordering by anesthetic drugs: relationship to synaptosomal sodium and calcium fluxes. Journal of Neurochemistry. 44: 1274-1281. PMID 2579208 DOI: 10.1111/J.1471-4159.1985.Tb08754.X |
0.262 |
|
| 2002 |
Hara K, Harris RA. The anesthetic mechanism of urethane: The effects on neurotransmitter-gated ion channels Anesthesia & Analgesia. 94: 313-318. DOI: 10.1213/00000539-200202000-00015 |
0.26 |
|
| 1987 |
Huidobro-Toro JP, Bleck V, Allan AM, Harris RA. Neurochemical actions of anesthetic drugs on the γ-aminobutyric acid receptor-chloride channel complex Journal of Pharmacology and Experimental Therapeutics. 242: 963-969. PMID 2443645 |
0.259 |
|
| 1989 |
Allan AM, Harris RA. Sensitivity to ethanol hypnosis and modulation of chloride channels does not cosegregate with pentobarbital sensitivity in HS mice Alcoholism: Clinical and Experimental Research. 13: 428-434. PMID 2473664 DOI: 10.1111/J.1530-0277.1989.TB00348.X |
0.258 |
|
| 1992 |
Leidenheimer NJ, Harris RA. Acute effects of ethanol on GABAA receptor function: molecular and physiological determinants. Advances in Biochemical Psychopharmacology. 47: 269-79. PMID 1324577 |
0.258 |
|
| 1979 |
Harris RA, Erickson CK. Alteration of ethanol effects by opiate antagonists Currents in Alcoholism. 5: 17-28. PMID 755620 |
0.255 |
|
| 1985 |
Harris RA, Bruno P. Effects of ethanol and other intoxicant-anesthetics on voltage-dependent sodium channels of brain synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 232: 401-6. PMID 2578564 |
0.255 |
|
| 1998 |
Minami K, Wick MJ, Stern-Bach Y, Dildy-Mayfield JE, Brozowski SJ, Gonzales EL, Trudell JR, Harris RA. Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors. The Journal of Biological Chemistry. 273: 8248-55. PMID 9525931 DOI: 10.1074/Jbc.273.14.8248 |
0.254 |
|
| 1994 |
Klein RL, Whiting PJ, Harris RA. Benzodiazepine treatment causes uncoupling of recombinant GABAA receptors expressed in stably transfected cells Journal of Neurochemistry. 63: 2349-2352. PMID 7964756 |
0.253 |
|
| 1996 |
Whatley VJ, Brozowski SJ, Hadingham KL, Whiting PJ, Harris RA. Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells Journal of Neurochemistry. 66: 1318-1321. PMID 8769900 |
0.252 |
|
| 1997 |
Eger EI, Koblin DD, Harris RA, Kendig JJ, Pohorille A, Halsey MJ, Trudell JR. Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites. Anesthesia and Analgesia. 84: 915-8. PMID 9085981 DOI: 10.1097/00000539-199704000-00039 |
0.249 |
|
| 2015 |
Bajo M, Herman MA, Varodayan FP, Oleata CS, Madamba SG, Harris RA, Blednov YA, Roberto M. Role of the IL-1 receptor antagonist in ethanol-induced regulation of GABAergic transmission in the central amygdala. Brain, Behavior, and Immunity. 45: 189-97. PMID 25479427 DOI: 10.1016/J.Bbi.2014.11.011 |
0.248 |
|
| 1992 |
Leidenheimer NJ, McQuilkin SJ, Hahner LD, Whiting P, Harris RA. Activation of protein kinase C selectively inhibits the gamma-aminobutyric acidA receptor: role of desensitization. Molecular Pharmacology. 41: 1116-23. PMID 1319547 |
0.248 |
|
| 1992 |
Dildy-Mayfield JE, Harris RA. Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 262: 487-94. PMID 1380078 |
0.247 |
|
| 1980 |
Harris RA, Snell D. Effects of acute and chronic administration of phenobarbital and d-amphetamine on schedule-controlled behavior Pharmacology, Biochemistry and Behavior. 12: 47-52. PMID 7367462 DOI: 10.1016/0091-3057(80)90414-1 |
0.247 |
|
| 1992 |
Dildy-Mayfield JE, Harris RA. Acute and chronic ethanol exposure alters the function of hippocampal kainate receptors expressed in Xenopus oocytes. Journal of Neurochemistry. 58: 1569-72. PMID 1312578 DOI: 10.1111/j.1471-4159.1992.tb11380.x |
0.246 |
|
| 1992 |
Lin LH, Chen LL, Zirrolli JA, Harris RA. General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium. The Journal of Pharmacology and Experimental Therapeutics. 263: 569-78. PMID 1331405 |
0.244 |
|
| 1982 |
Stokes JA, Harris RA. Alcohols and synaptosomal calcium transport. Molecular Pharmacology. 22: 99-104. PMID 7121453 |
0.238 |
|
| 1998 |
Weiner JL, Buhler AV, Whatley VJ, Harris RA, Dunwiddie TV. Colchicine is a competitive antagonist at human recombinant gamma-aminobutyric acidA receptors. The Journal of Pharmacology and Experimental Therapeutics. 284: 95-102. PMID 9435166 |
0.238 |
|
| 1985 |
Harris RA, Caldwell KK. Alcohol and the calcium-dependent potassium transport of human erythrocytes. Alcohol (Fayetteville, N.Y.). 2: 149-52. PMID 4015829 |
0.238 |
|
| 1993 |
Leidenheimer NJ, Whiting PJ, Harris RA. Activation of calcium-phospholipid-dependent protein kinase enhances benzodiazepine and barbiturate potentiation of the GABAA receptor Journal of Neurochemistry. 60: 1972-1975. PMID 8386229 |
0.236 |
|
| 1994 |
Machu TK, Harris RA. Alcohols and anesthetics enhance the function of 5-hydroxytryptamine3 receptors expressed in Xenopus laevis oocytes. The Journal of Pharmacology and Experimental Therapeutics. 271: 898-905. PMID 7965811 |
0.234 |
|
| 1988 |
Daniell LC, Brass EP, Harris RA. Effect of ethanol on intracellular ionized calcium concentrations in synaptosomes and hepatocytes. Molecular Pharmacology. 32: 831-7. PMID 3696160 |
0.233 |
|
| 1991 |
Hahner L, McQuilkin S, Harris RA. Cerebellar GABAB receptors modulate function of GABAA receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2466-72. PMID 1648524 DOI: 10.1096/fasebj.5.10.1648524 |
0.233 |
|
| 1996 |
Huidobro-Toro JP, Valenzuela CF, Harris RA. Modulation of GABAA receptor function by G protein-coupled 5-HT2C receptors. Neuropharmacology. 35: 1355-63. PMID 9014152 DOI: 10.1016/S0028-3908(96)00084-6 |
0.231 |
|
| 2016 |
Heusser SA, Howard RJ, Pouya I, Klement G, Borghese C, Harris RA, Lindahl E. A Single Mutation in GLIC Reveals Both the Potentiating and the Inhibitory Nature of Propofol Biophysical Journal. 110: 456a. DOI: 10.1016/J.Bpj.2015.11.2445 |
0.23 |
|
| 2002 |
Hara K, Harris RA. The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels. Anesthesia and Analgesia. 94: 313-8, table of cont. PMID 11812690 DOI: 10.1097/00000539-200202000-00015 |
0.23 |
|
| 2001 |
Eger EI, Fisher DM, Dilger JP, Sonner JM, Evers A, Franks NP, Harris RA, Kendig JJ, Lieb WR, Yamakura T. Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms. Anesthesiology. 94: 915-21. PMID 11388545 DOI: 10.1097/00000542-200105000-00032 |
0.23 |
|
| 2003 |
Blednov YA, Stoffel M, Alva H, Harris RA. A pervasive mechanism for analgesia: Activation of GIRK2 channels Proceedings of the National Academy of Sciences of the United States of America. 100: 277-282. PMID 12493843 DOI: 10.1073/Pnas.012682399 |
0.23 |
|
| 1988 |
Allan AM, Spuhler KP, Harris RA. γ-Aminobutyric acid-activated chloride channels: Relationship to genetic differences in ethanol sensitivity Journal of Pharmacology and Experimental Therapeutics. 244: 866-870. PMID 2472480 |
0.229 |
|
| 1985 |
Harris RA, Allan AM. Functional coupling of γ-aminobutyric acid receptors to chloride channels in brain membranes Science. 228: 1108-1110. PMID 2581319 DOI: 10.1126/SCIENCE.2581319 |
0.225 |
|
| 1984 |
Harris RA, Groh GI, Baxter DM, Hitzemann RJ. Gangliosides enhance the membrane actions of ethanol and pentobarbital. Molecular Pharmacology. 25: 410-7. PMID 6727863 |
0.223 |
|
| 2012 |
Reilly MT, Harris RA, Noronha A. Using genetically engineered animal models in the postgenomic era to understand gene function in alcoholism. Alcohol Research : Current Reviews. 34: 282-91. PMID 23134044 |
0.223 |
|
| 1984 |
Harris RA. Differential Effects of Membrane Perturbants on Voltage-Activated Sodium and Calcium Channels and Calcium-Dependent Potassium Channels Biophysical Journal. 45: 132-134. PMID 19431539 DOI: 10.1016/S0006-3495(84)84137-5 |
0.223 |
|
| 2005 |
Findlay GS, Harris RA, Blednov YA. Male transgenic glycine receptor α1 (S267Q) mutant mice display a hyperekplexia-like increase in acoustic startle responses Pharmacology Biochemistry and Behavior. 82: 215-222. PMID 16168470 DOI: 10.1016/J.Pbb.2005.08.011 |
0.221 |
|
| 2010 |
Sullivan EV, Harris RA, Pfefferbaum A. Alcohol's effects on brain and behavior. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 33: 127-43. PMID 23579943 |
0.221 |
|
| 1989 |
Lewin E, Peris J, Bleck V, Zahniser NR, Harris RA. Chemical kindling decreases GABA-activated chloride channels of mouse brain. European Journal of Pharmacology. 160: 101-6. PMID 2469590 DOI: 10.1016/0014-2999(89)90658-4 |
0.221 |
|
| 1988 |
Harris RA, Zaccaro LM, McQuilkin S, McClard A. Effects of ethanol and calcium on lipid order of membranes from mice selected for genetic differences in ethanol intoxication. Alcohol (Fayetteville, N.Y.). 5: 251-7. PMID 3415769 DOI: 10.1016/0741-8329(88)90060-2 |
0.22 |
|
| 1981 |
Harris RA. Ethanol and pentobarbital inhibition of intrasynaptosomal sequestration of calcium Biochemical Pharmacology. 30: 3209-3215. PMID 7317104 DOI: 10.1016/0006-2952(81)90520-7 |
0.22 |
|
| 1995 |
Dildy-Mayfield JE, Harris RA. Ethanol inhibits kainate responses of glutamate receptors expressed in Xenopus oocytes: role of calcium and protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3162-71. PMID 7536828 |
0.218 |
|
| 1979 |
Harris RA, Case J. Effects of maternal consumption of ethanol, barbital, or chlordiazepoxide on the behavior of the offspring. Behavioral and Neural Biology. 26: 234-47. PMID 496782 DOI: 10.1016/s0163-1047(79)92643-8 |
0.216 |
|
| 2003 |
Sonner JM, Antognini JF, Dutton RC, Flood P, Gray AT, Harris RA, Homanics GE, Kendig J, Orser B, Raines DE, Rampil IJ, Trudell J, Vissel B, Eger EI. Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesthesia and Analgesia. 97: 718-40. PMID 12933393 DOI: 10.1213/01.Ane.0000081063.76651.33 |
0.215 |
|
| 1991 |
Leidenheimer NJ, Machu TK, Endo S, Olsen RW, Harris RA, Browning MD. Cyclic AMP-dependent protein kinase decreases gamma-aminobutyric acidA receptor-mediated 36Cl- uptake by brain microsacs. Journal of Neurochemistry. 57: 722-5. PMID 1649259 DOI: 10.1111/j.1471-4159.1991.tb03806.x |
0.214 |
|
| 1990 |
Leidenheimer NJ, Browning MD, Dunwiddie TV, Hahner LD, Harris RA. Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function. Molecular Pharmacology. 38: 823-8. PMID 2174503 |
0.21 |
|
| 1993 |
Lin LH, Leonard S, Harris RA. Enflurane inhibits the function of mouse and human brain phosphatidylinositol-linked acetylcholine and serotonin receptors expressed in Xenopus oocytes. Molecular Pharmacology. 43: 941-8. PMID 8316225 |
0.209 |
|
| 1980 |
Fontaine RN, Harris RA, Schroeder F. Aminophospholipid asymmetry in murine synaptosomal plasma membrane Journal of Neurochemistry. 34: 269-277. PMID 6251164 DOI: 10.1111/J.1471-4159.1980.Tb06592.X |
0.209 |
|
| 1987 |
Mullin MJ, Dalton TK, Hunt WA, Harris RA, Majchrowicz E. Actions of ethanol on voltage-sensitive sodium channels: effects of acute and chronic ethanol treatment. The Journal of Pharmacology and Experimental Therapeutics. 242: 541-7. PMID 2441033 |
0.208 |
|
| 2023 |
Thoudam T, Chanda D, Lee JY, Jung MK, Sinam IS, Kim BG, Park BY, Kwon WH, Kim HJ, Kim M, Lim CW, Lee H, Huh YH, Miller CA, Saxena R, ... ... Harris RA, et al. Enhanced Ca-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease. Nature Communications. 14: 1703. PMID 36973273 DOI: 10.1038/s41467-023-37214-4 |
0.207 |
|
| 1995 |
Valenzuela CF, Kazlauskas A, Brozowski SJ, Weiner JL, Demali KA, McDonald BJ, Moss SJ, Dunwiddie TV, Harris RA. Platelet-derived growth factor receptor is a novel modulator of type A gamma-aminobutyric acid-gated ion channels. Molecular Pharmacology. 48: 1099-107. PMID 8848010 |
0.204 |
|
| 1996 |
Huidobro-Toro JP, Harris RA. Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. Proceedings of the National Academy of Sciences of the United States of America. 93: 8078-82. PMID 8755606 DOI: 10.1073/pnas.93.15.8078 |
0.204 |
|
| 2010 |
Harris RA, Allan AM. Response: GABA Receptor--Mediated Chloride Transport in a "Cell-Free" Membrane Preparation from Brain. Science (New York, N.Y.). 233: 229. PMID 17737293 DOI: 10.1126/science.233.4760.229 |
0.204 |
|
| 1984 |
Harris RA, Baxter DM, Mitchell MA, Hitzemann RJ. Physical properties and lipid composition of brain membranes from ethanol tolerant-dependent mice. Molecular Pharmacology. 25: 401-9. PMID 6539418 |
0.203 |
|
| 2022 |
Sun JX, Zhu KY, Wang YM, Wang DJ, Zhang MZ, Sarlus H, Benito-Cuesta I, Zhao XQ, Zou ZF, Zhong QY, Feng Y, Wu S, Wang YQ, Harris RA, Wang J. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function. Acta Pharmacologica Sinica. PMID 36229601 DOI: 10.1038/s41401-022-01000-7 |
0.199 |
|
| 1986 |
Allan AM, Harris RA. Anesthetic and convulsant barbiturates alter γ-aminobutyric acid-stimulated chloride flux across brain membranes Journal of Pharmacology and Experimental Therapeutics. 238: 763-768. PMID 2427687 |
0.198 |
|
| 1999 |
Eger EI, Ionescu P, Laster MJ, Gong D, Hudlicky T, Kendig JJ, Harris RA, Trudell JR, Pohorille A. Minimum alveolar anesthetic concentration of fluorinated alkanols in rats: relevance to theories of narcosis. Anesthesia and Analgesia. 88: 867-76. PMID 10195540 DOI: 10.1097/00000539-199904000-00035 |
0.198 |
|
| 2001 |
Eger E, Sonner J, Dilger J, Fisher D, Evers A, Franks N, Harris R, Kendig J, Lieb W, Yamakura T. What Are “Relevant” Concentrations? Anesthesiology. 95: 1538-1539. DOI: 10.1097/00000542-200112000-00050 |
0.197 |
|
| 1989 |
Schueler HE, Hitzemann RJ, Harris RA, Kreishman GP. Ethanol-induced differential disordering of the surface of synaptic plasma membranes from mice selected for genetic differences in ethanol intoxication. Progress in Clinical and Biological Research. 292: 425-34. PMID 2726918 |
0.196 |
|
| 1989 |
Dubovsky SL, Christiano J, Daniell LC, Franks RD, Murphy J, Adler L, Baker N, Harris RA. Increased platelet intracellular calcium concentration in patients with bipolar affective disorders. Archives of General Psychiatry. 46: 632-638. PMID 2735813 DOI: 10.1001/Archpsyc.1989.01810070058010 |
0.196 |
|
| 2004 |
Trudell JR, Harris RA. Are sobriety and consciousness determined by water in protein cavities? Alcoholism, Clinical and Experimental Research. 28: 1-3. PMID 14745295 DOI: 10.1097/01.Alc.0000108648.32241.Bd |
0.194 |
|
| 1989 |
Wafford KA, Dunwiddie TV, Harris RA. Calcium-dependent chloride currents elicited by injection of ethanol into Xenopus oocytes. Brain Research. 505: 215-9. PMID 2557132 DOI: 10.1016/0006-8993(89)91445-5 |
0.193 |
|
| 1989 |
Deitrich RA, Dunwiddie TV, Harris RA, Erwin VG. Mechanism of action of ethanol: initial central nervous system actions. Pharmacological Reviews. 41: 489-537. PMID 2700603 |
0.192 |
|
| 1997 |
Whatley VJ, Harris RA. The cytoskeleton and neurotransmitter receptors. International Review of Neurobiology. 39: 113-43. PMID 8894846 DOI: 10.1016/s0074-7742(08)60665-0 |
0.191 |
|
| 1996 |
Dildy-Mayfield JE, Eger EI, Harris RA. Anesthetics produce subunit-selective actions on glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 276: 1058-65. PMID 8786535 |
0.191 |
|
| 1993 |
Lin LH, Chen LL, Harris RA. Enflurane inhibits NMDA, AMPA, and kainate-induced currents in Xenopus oocytes expressing mouse and human brain mRNA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 479-85. PMID 7681790 DOI: 10.1096/fasebj.7.5.7681790 |
0.188 |
|
| 2012 |
Lee JH, Kim EJ, Kim DK, Lee JM, Park SB, Lee IK, Harris RA, Lee MO, Choi HS. Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERRγ. Plos One. 7: e46324. PMID 23050013 DOI: 10.1371/Journal.Pone.0046324 |
0.187 |
|
| 1983 |
Yamamoto HA, Harris RA. Effects of ethanol and barbiturates on Ca2+-ATPase activity of erythrocyte and brain membranes Biochemical Pharmacology. 32: 2787-2791. PMID 6226291 DOI: 10.1016/0006-2952(83)90093-X |
0.185 |
|
| 2008 |
Harris RA, Eger EI. Alzheimer's disease and anesthesia: out of body, out of mind...or not? Annals of Neurology. 64: 595-7. PMID 19107997 DOI: 10.1002/Ana.21575 |
0.185 |
|
| 1997 |
Hawes JW, Harper ET, Crabb DW, Harris RA. Structural and mechanistic aspects of a new family of dehydrogenases, the β-hydroxy acid dehydrogenases Advances in Experimental Medicine and Biology. 414: 395-402. PMID 9059644 DOI: 10.1007/978-1-4615-5871-2_45 |
0.184 |
|
| 2001 |
Crabb DW, Pinaire J, Chou WY, Sissom S, Peters JM, Harris RA, Stewart M. Peroxisome proliferator-activated receptors (PPAR) and the mitochondrial aldehyde dehydrogenase (ALDH2) promoter in vitro and in vivo. Alcoholism, Clinical and Experimental Research. 25: 945-52. PMID 11505017 |
0.182 |
|
| 2001 |
Wu P, Peters JM, Harris RA. Adaptive Increase in Pyruvate Dehydrogenase Kinase 4 during Starvation Is Mediated by Peroxisome Proliferator-Activated Receptor α Biochemical and Biophysical Research Communications. 287: 391-396. PMID 11554740 DOI: 10.1006/Bbrc.2001.5608 |
0.181 |
|
| 1987 |
Harris RA, Simon FR. What should hepatologists know about membrane fluidity? Hepatology. 7: 177-180. PMID 3026942 DOI: 10.1002/Hep.1840070132 |
0.18 |
|
| 2009 |
Guo JP, Verdrengh M, Tarkowski A, Lange S, Jennische E, Lorentzen JC, Harris RA. The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases. Genes and Immunity. 10: 227-36. PMID 19279651 DOI: 10.1038/gene.2009.4 |
0.179 |
|
| 2001 |
Blednov YA, Stoffel M, Chang SR, Harris RA. Potassium channels as targets for ethanol: Studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice Journal of Pharmacology and Experimental Therapeutics. 298: 521-530. PMID 11454913 |
0.177 |
|
| 1994 |
Lewin E, Bleck V, Dildy-Mayfield JE, Harris RA. GABAA and glutamate receptor subunit mRNAs in cortex of mice chemically kindled with FG 7142. Brain Research. Molecular Brain Research. 22: 320-2. PMID 8015388 |
0.177 |
|
| 1994 |
Dildy-Mayfield JE, Harris RA. Activation of protein kinase C inhibits kainate-induced currents in oocytes expressing glutamate receptor subunits. Journal of Neurochemistry. 62: 1639-42. PMID 8133291 DOI: 10.1046/j.1471-4159.1994.62041639.x |
0.175 |
|
| 2001 |
Yamakura T, Bertaccini E, Trudell JR, Harris RA. Anesthetics and ion channels: molecular models and sites of action. Annual Review of Pharmacology and Toxicology. 41: 23-51. PMID 11264449 DOI: 10.1146/annurev.pharmtox.41.1.23 |
0.174 |
|
| 1993 |
Crabb DW, Kedishvili NY, Popov KM, Rougraff P, Zhao Y, Harris RA. Evolutionary relationships of branched chain and non-specific alcohol and aldehyde dehydrogenases Advances in Experimental Medicine and Biology. 328: 523-532. PMID 8493932 DOI: 10.1007/978-1-4615-2904-0_55 |
0.173 |
|
| 1995 |
Valenzuela CF, Machu TK, McKernan RM, Whiting P, VanRenterghem BB, McManaman JL, Brozowski SJ, Smith GB, Olsen RW, Harris RA. Tyrosine kinase phosphorylation of GABAA receptors. Brain Research. Molecular Brain Research. 31: 165-72. PMID 7476025 DOI: 10.1016/0169-328X(95)00048-W |
0.172 |
|
| 1982 |
Harris RA, Cornell NW, Straight C, Veech RL. Mechanism responsible for aminooxyacetate and glycolate stimulation of ethanol oxidation by isolated hepatocytes. Archives of Biochemistry and Biophysics. 213: 414-25. PMID 7073285 DOI: 10.1016/0003-9861(82)90567-7 |
0.169 |
|
| 2019 |
Harris RA. John W. Holaday, Ph.D. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31659252 DOI: 10.1038/S41386-019-0558-6 |
0.167 |
|
| 1986 |
Allan AM, Harris RA. γ-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes Molecular Pharmacology. 29: 497-505. PMID 3010078 |
0.166 |
|
| 2016 |
Jung YS, Lee JM, Kim DK, Lee YS, Kim KS, Kim YH, Kim J, Lee MS, Lee IK, Kim SH, Cho SJ, Jeong WI, Lee CH, Harris RA, Choi HS. The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression. Plos One. 11: e0159425. PMID 27455076 DOI: 10.1371/journal.pone.0159425 |
0.166 |
|
| 2008 |
Noronha A, Harris RA. Maharaj K Ticku, 1948–2007 Neuropsychopharmacology. 33: 3247-3247. DOI: 10.1038/Npp.2008.25 |
0.165 |
|
| 2014 |
Imamura M, Chang BH, Kohjima M, Li M, Hwang B, Taegtmeyer H, Harris RA, Chan L. MondoA deficiency enhances sprint performance in mice. The Biochemical Journal. 464: 35-48. PMID 25145386 DOI: 10.1042/BJ20140530 |
0.165 |
|
| 1980 |
Hood WF, Harris RA. Effects of pentobarbital, ethanol and morphine on subcellular localization of calcium and magnesium in brain. Biochemical Pharmacology. 28: 3075-80. PMID 518706 DOI: 10.1016/0006-2952(79)90616-6 |
0.165 |
|
| 1999 |
Cardoso RA, Yamakura T, Brozowski SJ, Chavez-Noriega LE, Harris RA. Human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes predict efficacy of halogenated compounds that disobey the Meyer-Overton rule. Anesthesiology. 91: 1370-7. PMID 10551588 DOI: 10.1097/00000542-199911000-00029 |
0.164 |
|
| 2018 |
Lee JM, Han HS, Jung YS, Harris RA, Koo SH, Choi HS. The SMILE transcriptional corepressor inhibits cAMP response element-binding protein (CREB)-mediated transactivation of gluconeogenic genes. The Journal of Biological Chemistry. PMID 29950523 DOI: 10.1074/Jbc.Ra118.002196 |
0.164 |
|
| 2000 |
Michaëlsson J, Achour A, Salcedo M, Kâse-Sjöström A, Sundbäck J, Harris RA, Kärre K. Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers. European Journal of Immunology. 30: 300-7. PMID 10602053 DOI: 10.1002/1521-4141(200001)30:1<300::AID-IMMU300>3.0.CO;2-S |
0.163 |
|
| 1991 |
Leidenheimer NJ, Browning MD, Harris RA. GABAA receptor phosphorylation: multiple sites, actions and artifacts. Trends in Pharmacological Sciences. 12: 84-7. PMID 1647063 |
0.161 |
|
| 2012 |
Kim YD, Kim YH, Tadi S, Yu JH, Yim YH, Jeoung NH, Shong M, Hennighausen L, Harris RA, Lee IK, Lee CH, Choi HS. Metformin inhibits growth hormone-mediated hepatic PDK4 gene expression through induction of orphan nuclear receptor small heterodimer partner. Diabetes. 61: 2484-94. PMID 22698918 DOI: 10.2337/Db11-1665 |
0.161 |
|
| 2019 |
N'diaye M, Brauner S, Flytzani S, Kular L, Warnecke A, Adzemovic MZ, Piket E, Min JH, Edwards W, Mela F, Choi HY, Magg V, James T, Linden M, Reichardt HM, ... ... Harris RA, et al. C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation. The Journal of Clinical Investigation. PMID 31725411 DOI: 10.1172/JCI125857 |
0.16 |
|
| 2001 |
Blednov YA, Stoffel M, Cooper R, Wallace D, Mane N, Harris RA. Hyperactivity and dopamine D1 receptor activation in mice lacking girk2 channels. Psychopharmacology. 159: 370-8. PMID 11823889 DOI: 10.1007/s00213-001-0937-6 |
0.159 |
|
| 1983 |
Rohde BH, Harris RA. Effects of barbiturates and ethanol on muscimol-induced release of [3H]-D-aspartate from rodent cerebellum. Neuropharmacology. 22: 721-7. PMID 6888669 DOI: 10.1016/0028-3908(83)90096-5 |
0.158 |
|
| 1999 |
Harris RA, Eichholtz TJ, Hiles ID, Page MJ, O'Hare MJ. New model of ErbB-2 over-expression in human mammary luminal epithelial cells. International Journal of Cancer. 80: 477-84. PMID 9935193 DOI: 10.1002/(sici)1097-0215(19990129)80:3<477::aid-ijc23>3.0.co;2-w |
0.156 |
|
| 1992 |
Leidenheimer NJ, Harris RA. A transient osmotic permeabilization method for the introduction of impermeant molecules into functional brain membrane vesicles. Journal of Neuroscience Methods. 40: 233-41. PMID 1666165 DOI: 10.1016/0165-0270(91)90072-8 |
0.156 |
|
| 1996 |
Valenzuela CF, Xiong Z, MacDonald JF, Weiner JL, Frazier CJ, Dunwiddie TV, Kazlauskas A, Whiting PJ, Harris RA. Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. The Journal of Biological Chemistry. 271: 16151-9. PMID 8663218 DOI: 10.1074/Jbc.271.27.16151 |
0.154 |
|
| 2012 |
Ahn SW, Gang GT, Tadi S, Nedumaran B, Kim YD, Park JH, Kweon GR, Koo SH, Lee K, Ahn RS, Yim YH, Lee CH, Harris RA, Choi HS. Phosphoenolpyruvate carboxykinase and glucose-6-phosphatase are required for steroidogenesis in testicular Leydig cells. The Journal of Biological Chemistry. 287: 41875-87. PMID 23074219 DOI: 10.1074/Jbc.M112.421552 |
0.154 |
|
| 2013 |
She P, Bunpo P, Cundiff JK, Wek RC, Harris RA, Anthony TG. General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice. The Journal of Biological Chemistry. 288: 31250-60. PMID 24019515 DOI: 10.1074/Jbc.M113.498469 |
0.154 |
|
| 1982 |
Harris RA, Schroeder F. Effects of barbiturates and ethanol on the physical properties of brain membranes Journal of Pharmacology and Experimental Therapeutics. 223: 424-431. PMID 7131297 |
0.152 |
|
| 1981 |
Harris RA, Schroeder F. Effects of ethanol and related drugs on the physical and functional properties of brain membranes Currents in Alcoholism. 8: 461-468. PMID 7343190 |
0.152 |
|
| 2005 |
Kokkola R, Andersson A, Mullins G, Östberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA, Harris HE. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages Scandinavian Journal of Immunology. 61: 1-9. PMID 15644117 DOI: 10.1111/j.0300-9475.2005.01534.x |
0.152 |
|
| 1983 |
Harris RA. Ethanol, membrane perturbation, and synaptosomal ion transport Proceedings of the Western Pharmacology Society. 255-257. PMID 6889350 |
0.152 |
|
| 2004 |
Kwon HS, Huang B, Unterman TG, Harris RA. Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors. Diabetes. 53: 899-910. PMID 15047604 DOI: 10.2337/diabetes.53.4.899 |
0.152 |
|
| 2009 |
Gillett A, Maratou K, Fewings C, Harris RA, Jagodic M, Aitman T, Olsson T. Alternative splicing and transcriptome profiling of experimental autoimmune encephalomyelitis using genome-wide exon arrays. Plos One. 4: e7773. PMID 19915720 DOI: 10.1371/journal.pone.0007773 |
0.151 |
|
| 1981 |
Harris RA, Schroeder F. Ethanol and the physical properties of brain membranes. Fluorescence studies Molecular Pharmacology. 20: 128-137. PMID 7290080 |
0.149 |
|
| 2003 |
Djerbi M, Abdul-Majid KB, Abedi-Valugerdi M, Olsson T, Harris RA, Grandien A. Expression of the long form of human FLIP by retroviral gene transfer of hemopoietic stem cells exacerbates experimental autoimmune encephalomyelitis Journal of Immunology. 170: 2064-2073. PMID 12574377 DOI: 10.4049/jimmunol.170.4.2064 |
0.149 |
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| 2020 |
Jeon JH, Thoudam T, Choi EJ, Kim MJ, Harris RA, Lee IK. Loss of Metabolic Flexibility due to Overexpression of PDKs in Muscle, Liver, and the Immune System: Therapeutic Targets in Metabolic Diseases. Journal of Diabetes Investigation. PMID 32628351 DOI: 10.1111/Jdi.13345 |
0.149 |
|
| 2002 |
Huang B, Wu P, Bowker-Kinley MM, Harris RA. Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-alpha ligands, glucocorticoids, and insulin. Diabetes. 51: 276-83. PMID 11812733 DOI: 10.2337/DIABETES.51.2.276 |
0.148 |
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| 2014 |
Fransson M, Piras E, Wang H, Burman J, Duprez I, Harris RA, LeBlanc K, Magnusson PU, Brittebo E, Loskog AS. Intranasal delivery of central nervous system-retargeted human mesenchymal stromal cells prolongs treatment efficacy of experimental autoimmune encephalomyelitis. Immunology. 142: 431-41. PMID 24588452 DOI: 10.1111/imm.12275 |
0.147 |
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| 2006 |
Kwon HS, Huang B, Ho Jeoung N, Wu P, Steussy CN, Harris RA. Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. Biochimica Et Biophysica Acta. 1759: 141-51. PMID 16757381 DOI: 10.1016/J.Bbaexp.2006.04.005 |
0.145 |
|
| 1985 |
Polokoff MA, Simon TJ, Harris RA, Simon FR, Iwahashi M. Chronic ethanol increases liver plasma membrane fluidity. Biochemistry. 24: 3114-20. PMID 4027234 |
0.145 |
|
| 2011 |
Kellermayer R, Dowd SE, Harris RA, Balasa A, Schaible TD, Wolcott RD, Tatevian N, Szigeti R, Li Z, Versalovic J, Smith CW. Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1449-60. PMID 21228220 DOI: 10.1096/Fj.10-172205 |
0.144 |
|
| 2012 |
Scheffel J, Regen T, Van Rossum D, Seifert S, Ribes S, Nau R, Parsa R, Harris RA, Boddeke HW, Chuang HN, Pukrop T, Wessels JT, Jürgens T, Merkler D, Brück W, et al. Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia. 60: 1930-43. PMID 22911652 DOI: 10.1002/Glia.22409 |
0.144 |
|
| 1987 |
Peris J, Harris RA, Zahniser NR. Modulation of gamma-[3H]aminobutyric acid release from rat cortical slices by alpha 2-adrenoceptors. Neuroscience Letters. 80: 309-14. PMID 2825081 DOI: 10.1016/0304-3940(87)90473-3 |
0.143 |
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| 2018 |
Lund H, Pieber M, Parsa R, Han J, Grommisch D, Ewing E, Kular L, Needhamsen M, Espinosa A, Nilsson E, Överby AK, Butovsky O, Jagodic M, Zhang XM, Harris RA. Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells. Nature Communications. 9: 4845. PMID 30451869 DOI: 10.1038/s41467-018-07295-7 |
0.143 |
|
| 2020 |
Han J, Fan Y, Zhou K, Zhu K, Blomgren K, Lund H, Zhang XM, Harris RA. Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion. International Journal of Molecular Sciences. 21. PMID 33203068 DOI: 10.3390/ijms21228603 |
0.142 |
|
| 1978 |
Erickson CK, Tyler TD, Harris RA. Ethanol: modifications of acute intoxication by divalent cations. Science (New York, N.Y.). 199: 1219-21. PMID 343251 DOI: 10.1126/science.343251 |
0.142 |
|
| 1992 |
Hu H, Jaskiewicz JA, Harris RA. Ethanol and oleate inhibition of α-ketoisovalerate and 3-hydroxyisobutyrate metabolism by isolated hepatocytes Archives of Biochemistry and Biophysics. 299: 57-62. PMID 1444452 DOI: 10.1016/0003-9861(92)90243-P |
0.142 |
|
| 1980 |
Crabb DW, Jersild RA, McCune SA, Swartzentruber MS, Harris RA. Inhibition of hepatocyte proteolysis and lactate gluconeogenesis by chloroquine Archives of Biochemistry and Biophysics. 203: 49-57. PMID 7406512 DOI: 10.1016/0003-9861(80)90152-6 |
0.142 |
|
| 1985 |
Harris RA, Jones SB, Bruno P, Bylund DB. Effects of dihydropyridine derivatives and anticonvulsant drugs on [3H]nitrendipine binding and calcium and sodium fluxes in brain Biochemical Pharmacology. 34: 2187-2191. PMID 3159390 DOI: 10.1016/0006-2952(85)90416-2 |
0.142 |
|
| 2016 |
Yang T, Zollbrecht C, Winerdal ME, Zhuge Z, Zhang XM, Terrando N, Checa A, Sällström J, Wheelock CE, Winqvist O, Harris RA, Larsson E, Persson AE, Fredholm BB, Carlström M. Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. Journal of the American Heart Association. 5. PMID 27431647 DOI: 10.1161/Jaha.116.003868 |
0.141 |
|
| 2006 |
Joshi MA, Jeoung NH, Obayashi M, Hattab EM, Brocken EG, Liechty EA, Kubek MJ, Vattem KM, Wek RC, Harris RA. Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice. The Biochemical Journal. 400: 153-62. PMID 16875466 DOI: 10.1042/Bj20060869 |
0.141 |
|
| 2023 |
Harris RA, McAllister JM, Strauss JF. Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome. International Journal of Molecular Sciences. 24. PMID 37445796 DOI: 10.3390/ijms241310611 |
0.139 |
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| 2021 |
Guo M, Goudarzi KM, Abedi S, Pieber M, Sjöberg E, Behnan J, Zhang XM, Harris RA, Bartek J, Lindström MS, Nistér M, Hägerstrand D. SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma. Oncogene. PMID 34021259 DOI: 10.1038/s41388-021-01825-2 |
0.139 |
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| 2009 |
Covacu R, Arvidsson L, Andersson A, Khademi M, Erlandsson-Harris H, Harris RA, Svensson MA, Olsson T, Brundin L. TLR activation induces TNF-alpha production from adult neural stem/progenitor cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6889-95. PMID 19454685 DOI: 10.4049/jimmunol.0802907 |
0.137 |
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| 2020 |
Di Martino E, Bocchetta E, Tsuji S, Mukai T, Harris RA, Blomgren K, Ådén U. Defining a Time Window for Neuroprotection and Glia Modulation by Caffeine After Neonatal Hypoxia-Ischaemia. Molecular Neurobiology. PMID 31974940 DOI: 10.1007/s12035-020-01867-9 |
0.136 |
|
| 2023 |
An S, Nedumaran B, Koh H, Joo DJ, Lee H, Park CS, Harris RA, Shin KS, Djalilian AR, Kim YD. Enhancement of the SESN2-SHP cascade by melatonin ameliorates hepatic gluconeogenesis by inhibiting the CRBN-BTG2-CREBH signaling pathway. Experimental & Molecular Medicine. PMID 37488285 DOI: 10.1038/s12276-023-01040-x |
0.136 |
|
| 2015 |
Lee JM, Seo WY, Han HS, Oh KJ, Lee YS, Kim DK, Choi S, Choi BH, Harris RA, Lee CH, Koo SH, Choi HS. Insulin-inducible SMILE inhibits hepatic gluconeogenesis. Diabetes. PMID 26340929 DOI: 10.2337/db15-0249 |
0.136 |
|
| 1995 |
Patel MS, Harris RA. Mammalian Alpha -Keto Acid Dehydrogenase Complexes : Gene Regulation And Genetic Defects The Faseb Journal. 9: 1164-1172. PMID 7672509 DOI: 10.1096/Fasebj.9.12.7672509 |
0.135 |
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| 2019 |
Naiman S, Huynh FK, Gil R, Glick Y, Shahar Y, Touitou N, Nahum L, Avivi MY, Roichman A, Kanfi Y, Gertler AA, Doniger T, Ilkayeva OR, Abramovich I, Yaron O, ... ... Harris RA, et al. SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. Cell Reports. 29: 4127-4143.e8. PMID 31851938 DOI: 10.1016/J.Celrep.2019.11.067 |
0.134 |
|
| 2015 |
Hamilton J, Pellman JJ, Brustovetsky T, Harris RA, Brustovetsky N. Oxidative metabolism in YAC128 mouse model of Huntington's disease. Human Molecular Genetics. PMID 26041817 DOI: 10.1093/Hmg/Ddv209 |
0.133 |
|
| 1988 |
Daniell LC, Harris RA. Neuronal intracellular calcium concentrations are altered by anesthetics: relationship to membrane fluidization. The Journal of Pharmacology and Experimental Therapeutics. 245: 1-7. PMID 3361437 |
0.132 |
|
| 2003 |
Mackay A, Jones C, Dexter T, Silva RLA, Bulmer K, Jones A, Simpson P, Harris RA, Jat PS, Neville AM, Reis LFL, Lakhani SR, O'Hare MJ. cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells Oncogene. 22: 2680-2688. PMID 12730682 DOI: 10.1038/sj.onc.1206349 |
0.132 |
|
| 2009 |
Ma L, Buchold GM, Greenbaum MP, Roy A, Burns KH, Zhu H, Han DY, Harris RA, Coarfa C, Gunaratne PH, Yan W, Matzuk MM. GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. Plos Genetics. 5: e1000635. PMID 19730684 DOI: 10.1371/Journal.Pgen.1000635 |
0.13 |
|
| 1991 |
Buck KJ, Harris RA, Sikela JM. A general method for quantitative PCR analysis of mRNA levels for members of gene families: application to GABAA receptor subunits. Biotechniques. 11: 636-41. PMID 1725111 |
0.13 |
|
| 2015 |
Byun JK, Choi YK, Kang YN, Jang BK, Kang KJ, Jeon YH, Lee HW, Jeon JH, Koo SH, Jeong WI, Harris RA, Lee IK, Park KG. Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells. Hepatology (Baltimore, Md.). 61: 953-64. PMID 25346526 DOI: 10.1002/Hep.27577 |
0.13 |
|
| 1998 |
Huang B, Gudi R, Wu P, Harris RA, Hamilton J, Popov KM. Isoenzymes of Pyruvate Dehydrogenase Phosphatase DNA-DERIVED AMINO ACID SEQUENCES, EXPRESSION, AND REGULATION Journal of Biological Chemistry. 273: 17680-17688. PMID 9651365 DOI: 10.1074/Jbc.273.28.17680 |
0.13 |
|
| 2010 |
Gillett A, Thessen Hedreul M, Khademi M, Espinosa A, Beyeen AD, Jagodic M, Kockum I, Harris RA, Olsson T. Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 1056-65. PMID 20354066 DOI: 10.1177/1352458510364634 |
0.13 |
|
| 2001 |
Harris RA, Kobayashi R, Murakami T, Shimomura Y. Regulation of Branched-Chain α-Keto Acid Dehydrogenase Kinase Expression in Rat Liver Journal of Nutrition. 131. PMID 11238771 DOI: 10.1093/Jn/131.3.841S |
0.129 |
|
| 1989 |
Zhang B, Kuntz MJ, Goodwin GW, Edenberg HJ, Crabb DW, Harris RA. cDNA cloning of the E1α subunit of the branched-chain α-keto acid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease Annals of the New York Academy of Sciences. 573: 130-136. PMID 2634344 DOI: 10.1111/J.1749-6632.1989.Tb14991.X |
0.129 |
|
| 2004 |
Kwon HS, Harris RA. Mechanisms responsible for regulation of pyruvate dehydrogenase kinase 4 gene expression. Advances in Enzyme Regulation. 44: 109-21. PMID 15581486 DOI: 10.1016/J.Advenzreg.2003.11.020 |
0.128 |
|
| 2008 |
Andersson A, Covacu R, Sunnemark D, Danilov AI, Dal Bianco A, Khademi M, Wallström E, Lobell A, Brundin L, Lassmann H, Harris RA. Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis. Journal of Leukocyte Biology. 84: 1248-55. PMID 18644848 DOI: 10.1189/jlb.1207844 |
0.128 |
|
| 2015 |
Nagy-Szakal D, Mir SA, Harris RA, Dowd SE, Yamada T, Lacorazza HD, Tatevian N, Smith CW, de Zoeten EF, Klein J, Kellermayer R. Loss of n-6 fatty acid induced pediatric obesity protects against acute murine colitis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25903104 DOI: 10.1096/fj.14-267690 |
0.128 |
|
| 2006 |
Parker GE, Pederson BA, Obayashi M, Schroeder JM, Harris RA, Roach PJ. Gene expression profiling of mice with genetically modified muscle glycogen content. The Biochemical Journal. 395: 137-45. PMID 16356168 DOI: 10.1042/Bj20051456 |
0.127 |
|
| 2012 |
Davies MN, Volta M, Pidsley R, Lunnon K, Dixit A, Lovestone S, Coarfa C, Harris RA, Milosavljevic A, Troakes C, Al-Sarraj S, Dobson R, Schalkwyk LC, Mill J. Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biology. 13: R43. PMID 22703893 DOI: 10.1186/Gb-2012-13-6-R43 |
0.127 |
|
| 2017 |
Warnecke A, Abele S, Musunuri S, Bergquist J, Harris RA. Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages. Neuromolecular Medicine. PMID 28828577 DOI: 10.1007/s12017-017-8461-y |
0.126 |
|
| 1989 |
Daniell LC, Harris RA. Ethanol and inositol 1,4,5-trisphosphate release calcium from separate stores of brain microsomes Journal of Pharmacology and Experimental Therapeutics. 250: 875-881. PMID 2778717 |
0.126 |
|
| 2021 |
Tapmeier TT, Rahmioglu N, Lin J, De Leo B, Obendorf M, Raveendran M, Fischer OM, Bafligil C, Guo M, Harris RA, Hess-Stumpp H, Laux-Biehlmann A, Lowy E, Lunter G, Malzahn J, et al. Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis. Science Translational Medicine. 13. PMID 34433639 DOI: 10.1126/scitranslmed.abd6469 |
0.124 |
|
| 2005 |
Harris RA, Joshi M, Jeoung NH, Obayashi M. Overview of the molecular and biochemical basis of branched-chain amino acid catabolism. The Journal of Nutrition. 135: 1527S-30S. PMID 15930464 DOI: 10.1093/Jn/135.6.1527S |
0.124 |
|
| 2009 |
Thessen Hedreul M, Gillett A, Olsson T, Jagodic M, Harris RA. Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 210: 30-9. PMID 19269041 DOI: 10.1016/j.jneuroim.2009.02.010 |
0.124 |
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