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Renjian Zheng, Ph.D. - Publications

Affiliations: 
2001 Yeshiva University, New York, NY, United States 
Area:
Enzymology
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Osterbur ML, Zheng R, Marion R, Walsh C, McDonald TV. An Interdomain KCNH2 Mutation Produces an Intermediate Long QT Syndrome. Human Mutation. 36: 764-73. PMID 25914329 DOI: 10.1002/Humu.22805  0.321
2014 Donaldson TM, Ting LM, Zhan C, Shi W, Zheng R, Almo SC, Kim K. Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase. Plos One. 9: e84384. PMID 24416224 DOI: 10.1371/Journal.Pone.0084384  0.384
2012 Zheng R, Negro BW, Rojas RA, Laska A, Cho S, Cheng H, Obeg-Gyimah E, McDonald T. Ligand-Binding Characteristics of the Cyclic Nucleotide Binding Domain (CNBD) of the HERG Potassium Channel and Long QT Syndrome Biophysical Journal. 102: 329a. DOI: 10.1016/J.Bpj.2011.11.1803  0.314
2010 Ren XQ, Liu GX, Organ-Darling LE, Zheng R, Roder K, Jindal HK, Centracchio J, McDonald TV, Koren G. Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1525-34. PMID 20833965 DOI: 10.1152/Ajpheart.00479.2009  0.302
2010 Zheng R, Thompson K, Obeng-Gyimah E, Alessi D, Chen J, Cheng H, McDonald TV. Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. The Biochemical Journal. 428: 75-84. PMID 20196769 DOI: 10.1042/Bj20090977  0.316
2010 Chen J, Zheng R, Negro BW, McDonald TV. Physical and Functional Interactions Between the KCNQ1 and KCNE1 C-Terminal Domains Biophysical Journal. 98: 121a. DOI: 10.1016/J.Bpj.2009.12.660  0.308
2009 Chen J, Zheng R, Melman YF, McDonald TV. Functional interactions between KCNE1 C-terminus and the KCNQ1 channel. Plos One. 4: e5143. PMID 19340287 DOI: 10.1371/Journal.Pone.0005143  0.301
2009 Zheng R, Thompson K, Alessi D, Obeng-Gyimah E, McDonald TV. Physical Interactions Between The Cytoplasmic Domains Of KCNQ1 And KCNE1 Channel Subunits Biophysical Journal. 96: 190a. DOI: 10.1016/J.Bpj.2008.12.892  0.304
2004 Zheng R, Dam TK, Brewer CF, Blanchard JS. Active site residues in Mycobacterium tuberculosis pantothenate synthetase required in the formation and stabilization of the adenylate intermediate Biochemistry. 43: 7171-7178. PMID 15170354 DOI: 10.1021/Bi049676N  0.601
2003 Zheng R, Blanchard JS. Substrate specificity and kinetic isotope effect analysis of the Eschericia coli ketopantoate reductase Biochemistry. 42: 11289-11296. PMID 14503879 DOI: 10.1021/Bi030101K  0.543
2003 Cirilli M, Zheng R, Scapin G, Blanchard JS. The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity Biochemistry. 42: 10644-10650. PMID 12962488 DOI: 10.1021/Bi030044V  0.631
2003 Vogt RN, Steenkamp DJ, Zheng R, Blanchard JS. The metabolism of nitrosothiols in the mycobacteria: Identification and characterization of S-nitrosomycothiol reductase Biochemical Journal. 374: 657-665. PMID 12809551 DOI: 10.1042/Bj20030642  0.588
2003 Williams L, Zheng R, Blanchard JS, Raushel FM. Positional isotope exchange analysis of the pantothenate synthetase reaction. Biochemistry. 42: 5108-13. PMID 12718554 DOI: 10.1021/Bi0340853  0.57
2003 Magnet S, Smith TA, Zheng R, Nordmann P, Blanchard JS. Aminoglycoside resistance resulting from tight drug binding to an altered aminoglycoside acetyltransferase. Antimicrobial Agents and Chemotherapy. 47: 1577-83. PMID 12709325 DOI: 10.1128/Aac.47.5.1577-1583.2003  0.553
2003 Sugantino M, Zheng R, Yu M, Blanchard JS. Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids. Biochemistry. 42: 191-9. PMID 12515554 DOI: 10.1021/Bi020516Q  0.642
2001 Zheng R, Blanchard JS. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase. Biochemistry. 40: 12904-12. PMID 11669627 DOI: 10.1021/Bi011522+  0.545
2000 Zheng R, Blanchard JS. Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue. Biochemistry. 39: 16244-51. PMID 11123955 DOI: 10.1021/Bi002134V  0.588
2000 Caplan JF, Zheng R, Blanchard JS, Vederas JC. Vinylogous amide analogues of diaminopimelic acid (DAP) as inhibitors of enzymes involved in bacterial lysine biosynthesis. Organic Letters. 2: 3857-60. PMID 11101437 DOI: 10.1021/Ol000271E  0.567
2000 Zheng R, Blanchard JS. Kinetic and mechanistic analysis of the E. coli panE-encoded ketopantoate reductase. Biochemistry. 39: 3708-17. PMID 10736170 DOI: 10.1021/Bi992676G  0.555
1998 Cirilli M, Zheng R, Scapin G, Blanchard JS. Structural symmetry: the three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase. Biochemistry. 37: 16452-8. PMID 9843410 DOI: 10.1021/Bi982138O  0.573
1998 Basso LA, Zheng R, Musser JM, Jacobs WR, Blanchard JS. Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates. The Journal of Infectious Diseases. 178: 769-75. PMID 9728546 DOI: 10.1086/515362  0.602
1998 Born TL, Zheng R, Blanchard JS. Hydrolysis of N-succinyl-L,L-diaminopimelic acid by the Haemophilus influenzae dapE-encoded desuccinylase: metal activation, solvent isotope effects, and kinetic mechanism. Biochemistry. 37: 10478-87. PMID 9671518 DOI: 10.1021/Bi9806807  0.553
1997 Scapin G, Reddy SG, Zheng R, Blanchard JS. Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry. 36: 15081-8. PMID 9398235 DOI: 10.1021/Bi9719915  0.601
1997 Basso LA, Zheng R, Musser JM, Blanchard JS. Nadh binding to wild-type and mutant forms of inha from isoniazid-resistant clinical isolates of mycobacterium tuberculosis Faseb Journal. 11: A1441.  0.482
1997 Ledwidge R, Zheng R, Blanchard JS. Identification of the argD-encoded n-acetylornithine aminotransferase as n-succinyldiaminopimelate transaminase Faseb Journal. 11: A1320.  0.4
1996 Basso LA, Zheng R, Blanchard JS. Kinetics of inactivation of WT and C243S mutant of Mycobacterium tuberculosis enoyl reductase by activated isoniazid Journal of the American Chemical Society. 118: 11301-11302. DOI: 10.1021/Ja962035Y  0.547
1995 Zheng R, Cenas N, Blanchard JS. Catalytic and potentiometric characterization of E201D and E201Q mutants of Trypanosoma congolense trypanothione reductase. Biochemistry. 34: 12697-703. PMID 7548022 DOI: 10.1021/Bi00039A028  0.57
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