Michael Karin - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
immunology

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhong Z, Sanchez-Lopez E, Karin M. Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment. Cell. 166: 288-98. PMID 27419869 DOI: 10.1016/J.Cell.2016.05.051  0.36
2016 Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, ... ... Karin M, et al. p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells. Cancer Cell. PMID 27211490 DOI: 10.1016/J.Ccell.2016.04.006  0.36
2016 Karin M, Dhar D. Liver Carcinogenesis: From Naughty Chemicals to Soothing Fat- and the Surprising Role of NRF2. Carcinogenesis. PMID 27207669 DOI: 10.1093/Carcin/Bgw060  0.36
2016 Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, ... ... Karin M, et al. NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria. Cell. 164: 896-910. PMID 26919428 DOI: 10.1016/J.Cell.2015.12.057  0.36
2016 Karin M, Clevers H. Reparative inflammation takes charge of tissue regeneration. Nature. 529: 307-15. PMID 26791721 DOI: 10.1038/nature17039  0.36
2016 Font-Burgada J, Sun B, Karin M. Obesity and Cancer: The Oil that Feeds the Flame. Cell Metabolism. 23: 48-62. PMID 26771116 DOI: 10.1016/j.cmet.2015.12.015  0.36
2015 Antonucci L, Fagman JB, Kim JY, Todoric J, Gukovsky I, Mackey M, Ellisman MH, Karin M. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 26512112 DOI: 10.1073/pnas.1519384112  0.36
2015 Shalapour S, Karin M. Immunity, inflammation, and cancer: an eternal fight between good and evil. The Journal of Clinical Investigation. 125: 3347-55. PMID 26325032 DOI: 10.1172/JCI80007  0.36
2015 Strasner A, Karin M. Immune Infiltration and Prostate Cancer. Frontiers in Oncology. 5: 128. PMID 26217583 DOI: 10.3389/fonc.2015.00128  0.36
2015 Wang K, Karin M. Tumor-Elicited Inflammation and Colorectal Cancer. Advances in Cancer Research. 128: 173-96. PMID 26216633 DOI: 10.1016/Bs.Acr.2015.04.014  0.36
2015 Vlahopoulos SA, Cen O, Hengen N, Agan J, Moschovi M, Critselis E, Adamaki M, Bacopoulou F, Copland JA, Boldogh I, Karin M, Chrousos GP. Dynamic aberrant NF-κB spurs tumorigenesis: a new model encompassing the microenvironment. Cytokine & Growth Factor Reviews. 26: 389-403. PMID 26119834 DOI: 10.1016/j.cytogfr.2015.06.001  0.36
2015 Moroishi T, Park HW, Qin B, Chen Q, Meng Z, Plouffe SW, Taniguchi K, Yu FX, Karin M, Pan D, Guan KL. A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis. Genes & Development. 29: 1271-84. PMID 26109050 DOI: 10.1101/gad.262816.115  0.36
2015 Wu X, Karin M. Emerging roles of Lys63-linked polyubiquitylation in immune responses. Immunological Reviews. 266: 161-74. PMID 26085214 DOI: 10.1111/imr.12310  0.36
2015 Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, ... Karin M, et al. Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy. Nature. 521: 94-8. PMID 25924065 DOI: 10.1038/Nature14395  0.36
2015 Wree A, Johnson CD, Font-Burgada J, Eguchi A, Povero D, Karin M, Feldstein AE. Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation. Cell Death and Differentiation. PMID 25909884 DOI: 10.1038/cdd.2015.46  0.36
2015 Shaked H, Guma M, Karin M. Analysis of NF-κB activation in mouse intestinal epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 1280: 593-606. PMID 25736774 DOI: 10.1007/978-1-4939-2422-6_35  0.36
2015 Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, ... ... Karin M, et al. A gp130-Src-YAP module links inflammation to epithelial regeneration. Nature. 519: 57-62. PMID 25731159 DOI: 10.1038/Nature14228  0.36
2015 Kobayashi K, Toguchida J, Karin M, Kato T. IKKβ in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5. Cell Death and Differentiation. 22: 852-61. PMID 25526093 DOI: 10.1038/cdd.2014.192  0.36
2015 Morrison A, Chen L, Wang J, Zhang M, Yang H, Ma Y, Budanov A, Lee JH, Karin M, Li J. Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 408-17. PMID 25366347 DOI: 10.1096/fj.14-258814  0.36
2015 Guma M, Sanchez-Lopez E, Lodi A, Garcia-Carbonell R, Tiziani S, Karin M, Lacal JC, Firestein GS. Choline kinase inhibition in rheumatoid arthritis. Annals of the Rheumatic Diseases. 74: 1399-407. PMID 25274633 DOI: 10.1136/Annrheumdis-2014-205696  0.36
2015 Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, Taniguchi K, Nakagawa H, Valasek MA, Ye L, Kopp JL, Sander M, Carter H, Deisseroth K, Verma IM, ... Karin M, et al. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer Cell. 162: 766-779. DOI: 10.1016/j.cell.2015.07.026  0.36
2014 Wang K, Kim MK, Di Caro G, Wong J, Shalapour S, Wan J, Zhang W, Zhong Z, Sanchez-Lopez E, Wu LW, Taniguchi K, Feng Y, Fearon E, Grivennikov SI, Karin M. Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis. Immunity. 41: 1052-63. PMID 25526314 DOI: 10.1016/J.Immuni.2014.11.009  0.36
2014 Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV. Sestrins inhibit mTORC1 kinase activation through the GATOR complex. Cell Reports. 9: 1281-91. PMID 25457612 DOI: 10.1016/J.Celrep.2014.10.019  0.36
2014 Yang J, Hawkins OE, Barham W, Gilchuk P, Boothby M, Ayers GD, Joyce S, Karin M, Yull FE, Richmond A. Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response. Cancer Research. 74: 7274-84. PMID 25336190 DOI: 10.1158/0008-5472.Can-14-1091  0.36
2014 Wolf MJ, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, Ringelhan M, Simonavicius N, Egger M, Wohlleber D, Lorentzen A, Einer C, Schulz S, Clavel T, Protzer U, ... ... Karin M, et al. Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. Cancer Cell. 26: 549-64. PMID 25314080 DOI: 10.1016/J.Ccell.2014.09.003  0.36
2014 Karin M. Whipping NF-κB to Submission via GADD45 and MKK7. Cancer Cell. 26: 447-9. PMID 25314072 DOI: 10.1016/j.ccell.2014.09.012  0.36
2014 Ammirante M, Shalapour S, Kang Y, Jamieson CA, Karin M. Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 111: 14776-81. PMID 25267627 DOI: 10.1073/pnas.1416498111  0.36
2014 Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, ... Karin M, et al. IKKα negatively regulates ASC-dependent inflammasome activation. Nature Communications. 5: 4977. PMID 25266676 DOI: 10.1038/Ncomms5977  0.36
2014 Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. The Embo Journal. 33: 2581-96. PMID 25260751 DOI: 10.15252/embj.201488351  0.36
2014 Yang L, Karin M. Roles of tumor suppressors in regulating tumor-associated inflammation. Cell Death and Differentiation. 21: 1677-86. PMID 25190145 DOI: 10.1038/cdd.2014.131  0.36
2014 Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, ... ... Karin M, et al. Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. Proceedings of the National Academy of Sciences of the United States of America. 111: 13870-5. PMID 25189770 DOI: 10.1073/Pnas.1414358111  0.36
2014 Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, Zhong Z, Valasek MA, Seki E, Hidalgo J, Koike K, Kaufman RJ, Karin M. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell. 26: 331-43. PMID 25132496 DOI: 10.1016/J.Ccr.2014.07.001  0.36
2014 Fang DF, He K, Wang N, Sang ZH, Qiu X, Xu G, Jian Z, Liang B, Li T, Li HY, Li AL, Zhou T, Gong WL, Yang B, Karin M, et al. NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation. Nature Communications. 5: 4513. PMID 25072696 DOI: 10.1038/ncomms5513  0.36
2014 Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, ... ... Karin M, et al. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. The Journal of Clinical Investigation. 124: 3566-78. PMID 24983318 DOI: 10.1172/Jci74068  0.36
2014 Umemura A, Park EJ, Taniguchi K, Lee JH, Shalapour S, Valasek MA, Aghajan M, Nakagawa H, Seki E, Hall MN, Karin M. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metabolism. 20: 133-44. PMID 24910242 DOI: 10.1016/J.Cmet.2014.05.001  0.36
2014 Sun B, Karin M. The therapeutic value of targeting inflammation in gastrointestinal cancers. Trends in Pharmacological Sciences. 35: 349-57. PMID 24881011 DOI: 10.1016/j.tips.2014.04.011  0.36
2014 Valeri N, Braconi C, Gasparini P, Murgia C, Lampis A, Paulus-Hock V, Hart JR, Ueno L, Grivennikov SI, Lovat F, Paone A, Cascione L, Sumani KM, Veronese A, Fabbri M, ... ... Karin M, et al. MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer. Cancer Cell. 25: 469-83. PMID 24735923 DOI: 10.1016/S0140-6736(13)60457-2  0.36
2014 Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Seminars in Immunology. 26: 54-74. PMID 24552665 DOI: 10.1016/j.smim.2014.01.001  0.36
2014 Karin M, Jobin C, Balkwill F. Chemotherapy, immunity and microbiota--a new triumvirate? Nature Medicine. 20: 126-7. PMID 24504404 DOI: 10.1038/nm.3473  0.36
2014 Woo JR, Liss MA, Muldong MT, Palazzi K, Strasner A, Ammirante M, Varki N, Shabaik A, Howell S, Kane CJ, Karin M, Jamieson CA. Tumor infiltrating B-cells are increased in prostate cancer tissue. Journal of Translational Medicine. 12: 30. PMID 24475900 DOI: 10.1186/1479-5876-12-30  0.36
2014 Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y. Critical role for IL-1β in DNA damage-induced mucositis. Proceedings of the National Academy of Sciences of the United States of America. 111: E702-11. PMID 24469832 DOI: 10.1073/Pnas.1322691111  0.36
2014 Wilson CL, Mann J, Walsh M, Perrugoria MJ, Oakley F, Wright MC, Brignole C, Di Paolo D, Perri P, Ponzoni M, Karin M, Mann DA. Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3. Plos One. 9: e83391. PMID 24416163 DOI: 10.1371/journal.pone.0083391  0.36
2014 Dhar D, Seki E, Karin M. NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet. Cell Metabolism. 19: 6-7. PMID 24411937 DOI: 10.1016/J.Cmet.2013.12.010  0.36
2014 Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, ... ... Karin M, et al. Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 111: 1090-5. PMID 24395807 DOI: 10.1073/Pnas.1322731111  0.36
2014 Moles A, Murphy L, Wilson CL, Chakraborty JB, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. Journal of Hepatology. 60: 782-91. PMID 24333183 DOI: 10.1016/J.Jhep.2013.12.005  0.36
2014 Bonnegarde-Bernard A, Jee J, Fial MJ, Aeffner F, Cormet-Boyaka E, Davis IC, Lin M, Tomé D, Karin M, Sun Y, Boyaka PN. IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites. Mucosal Immunology. 7: 257-67. PMID 23839064 DOI: 10.1038/mi.2013.43  0.36
2014 Authier H, Billot K, Derudder E, Bordereaux D, Rivière P, Rodrigues-Ferreira S, Nahmias C, Baud V, Karin M. IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors Proceedings of the National Academy of Sciences of the United States of America. 111: 14794-14799. DOI: 10.1073/pnas.1410124111/-/DCSupplemental  0.36
2013 Chen S, Yueh MF, Bigo C, Barbier O, Wang K, Karin M, Nguyen N, Tukey RH. Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proceedings of the National Academy of Sciences of the United States of America. 110: 19143-8. PMID 24191041 DOI: 10.1073/Pnas.1319123110  0.36
2013 He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, ... ... Karin M, et al. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell. 155: 384-96. PMID 24120137 DOI: 10.1016/J.Cell.2013.09.031  0.36
2013 Ma J, Bang BR, Lu J, Eun SY, Otsuka M, Croft M, Tobias P, Han J, Takeuchi O, Akira S, Karin M, Yagita H, Kang YJ. The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. Science Signaling. 6: ra87. PMID 24084649 DOI: 10.1126/scisignal.2004431  0.36
2013 Lee JH, Budanov AV, Karin M. Sestrins orchestrate cellular metabolism to attenuate aging. Cell Metabolism. 18: 792-801. PMID 24055102 DOI: 10.1016/j.cmet.2013.08.018  0.36
2013 Ammirante M, Kuraishy AI, Shalapour S, Strasner A, Ramirez-Sanchez C, Zhang W, Shabaik A, Karin M. An IKKα-E2F1-BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence. Genes & Development. 27: 1435-40. PMID 23796898 DOI: 10.1101/Gad.220202.113  0.36
2013 Sun B, Karin M. Inflammation and liver tumorigenesis. Frontiers of Medicine. 7: 242-54. PMID 23681888 DOI: 10.1007/s11684-013-0256-4  0.36
2013 Gukovsky I, Li N, Todoric J, Gukovskaya A, Karin M. Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology. 144: 1199-209.e4. PMID 23622129 DOI: 10.1053/j.gastro.2013.02.007  0.36
2013 Zhang W, Tan W, Wu X, Poustovoitov M, Strasner A, Li W, Borcherding N, Ghassemian M, Karin M. A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1. Cancer Cell. 23: 647-59. PMID 23602409 DOI: 10.1016/J.Ccr.2013.03.012  0.36
2013 Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, ... ... Karin M, et al. Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. The Journal of Clinical Investigation. 123: 2231-43. PMID 23563314 DOI: 10.1172/Jci64498  0.36
2013 Simonin Y, Vegna S, Akkari L, Grégoire D, Antoine E, Piette J, Floc'h N, Lassus P, Yu GY, Rosenberg AR, Karin M, Durantel D, Hibner U. Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis. Plos Pathogens. 9: e1003234. PMID 23555249 DOI: 10.1371/journal.ppat.1003234  0.36
2013 Mancino A, Habbeddine M, Johnson E, Luron L, Bebien M, Memet S, Fong C, Bajenoff M, Wu X, Karin M, Caamano J, Chi H, Seed M, Lawrence T. I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection. The Embo Journal. 32: 816-28. PMID 23422957 DOI: 10.1038/emboj.2013.28  0.36
2013 Du H, Sun X, Guma M, Luo J, Ouyang H, Zhang X, Zeng J, Quach J, Nguyen DH, Shaw PX, Karin M, Zhang K. JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 2377-82. PMID 23341606 DOI: 10.1073/pnas.1221729110  0.36
2013 Sakurai T, Kudo M, Umemura A, He G, Elsharkawy AM, Seki E, Karin M. p38α inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species. Cancer Research. 73: 215-24. PMID 23271722 DOI: 10.1158/0008-5472.CAN-12-1602  0.36
2013 Wang K, Grivennikov SI, Karin M. Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases. Annals of the Rheumatic Diseases. 72: ii100-3. PMID 23253923 DOI: 10.1136/Annrheumdis-2012-202201  0.36
2013 Mazor R, Alsaigh T, Shaked H, Altshuler AE, Pocock ES, Kistler EB, Karin M, Schmid-Schönbein GW. Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells. The Journal of Biological Chemistry. 288: 598-607. PMID 23155052 DOI: 10.1074/Jbc.M112.417451  0.36
2013 Wang K, Grivennikov S, Karin M. Innate immunity, inflammation and colorectal cancer Innate Immunity: Resistance and Disease-Promoting Principles. 4: 4-10. DOI: 10.1159/000346526  0.36
2012 Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, Taniguchi K, Yu GY, Osterreicher CH, Hung KE, Datz C, Feng Y, Fearon ER, Oukka M, Tessarollo L, ... ... Karin M, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 491: 254-8. PMID 23034650 DOI: 10.1038/Nature11465  0.36
2012 Yu GY, He G, Li CY, Tang M, Grivennikov S, Tsai WT, Wu MS, Hsu CW, Tsai Y, Wang LH, Karin M. Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine production. Molecular Cell. 48: 313-21. PMID 22959272 DOI: 10.1016/j.molcel.2012.07.032  0.36
2012 Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, ... ... Karin M, et al. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metabolism. 16: 311-21. PMID 22958918 DOI: 10.1016/J.Cmet.2012.08.004  0.36
2012 Shaked H, Hofseth LJ, Chumanevich A, Chumanevich AA, Wang J, Wang Y, Taniguchi K, Guma M, Shenouda S, Clevers H, Harris CC, Karin M. Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14007-12. PMID 22893683 DOI: 10.1073/Pnas.1211509109  0.36
2012 Gaba A, Grivennikov SI, Do MV, Stumpo DJ, Blackshear PJ, Karin M. Cutting edge: IL-10-mediated tristetraprolin induction is part of a feedback loop that controls macrophage STAT3 activation and cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 189: 2089-93. PMID 22865915 DOI: 10.4049/jimmunol.1201126  0.36
2012 Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T. The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. Plos Pathogens. 8: e1002812. PMID 22829768 DOI: 10.1371/Journal.Ppat.1002812  0.36
2012 Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 143: 307-20. PMID 22705006 DOI: 10.1053/j.gastro.2012.06.004  0.36
2012 Font-Burgada J, Seki E, Karin M. CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction. Cancer Cell. 21: 711-2. PMID 22698394 DOI: 10.1016/j.ccr.2012.05.034  0.36
2012 Balkhi MY, Willette-Brown J, Zhu F, Chen Z, Liu S, Guttridge DC, Karin M, Hu Y. IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis. Blood. 119: 5467-77. PMID 22544702 DOI: 10.1182/blood-2012-01-401547  0.36
2012 Guma M, Hammaker D, Topolewski K, Corr M, Boyle DL, Karin M, Firestein GS. Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6. Arthritis and Rheumatism. 64: 2887-95. PMID 22488549 DOI: 10.1002/art.34489  0.36
2012 DiDonato JA, Mercurio F, Karin M. NF-κB and the link between inflammation and cancer. Immunological Reviews. 246: 379-400. PMID 22435567 DOI: 10.1111/j.1600-065X.2012.01099.x  0.36
2012 Lancaster GI, Skiba B, Yang C, Nicholls HT, Langley KG, Chan MH, Bruce CR, Rewcastle GW, Shepherd PR, Karin M, Febbraio MA. IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade. The Biochemical Journal. 442: 723-32. PMID 22364283 DOI: 10.1042/BJ4520171  0.36
2012 Aghajan M, Li N, Karin M. Obesity, autophagy and the pathogenesis of liver and pancreatic cancers. Journal of Gastroenterology and Hepatology. 27: 10-4. PMID 22320909 DOI: 10.1111/j.1440-1746.2011.07008.x  0.36
2012 Delhase M, Kim SY, Lee H, Naiki-Ito A, Chen Y, Ahn ER, Murata K, Kim SJ, Lautsch N, Kobayashi KS, Shirai T, Karin M, Nakanishi M. TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2. Proceedings of the National Academy of Sciences of the United States of America. 109: E177-86. PMID 22203995 DOI: 10.1073/pnas.1119296109  0.36
2012 Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, ... ... Karin M, et al. IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression. Molecular Cell. 45: 171-84. PMID 22196886 DOI: 10.1016/J.Molcel.2011.11.018  0.36
2012 Sun B, Karin M. Obesity, inflammation, and liver cancer. Journal of Hepatology. 56: 704-13. PMID 22120206 DOI: 10.1016/j.jhep.2011.09.020  0.36
2012 Fujiwara R, Chen S, Karin M, Tukey RH. Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. Gastroenterology. 142: 109-118.e2. PMID 21983082 DOI: 10.1053/J.Gastro.2011.09.045  0.36
2012 Deok Kong S, Zhang W, Hee Lee J, Choi C, Khamwannah J, Karin M, Jin S. Externally triggered on-demand drug release and deep tumor penetration Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics. 30. DOI: 10.1116/1.3694833  0.36
2012 Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF, Karin M. Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation Journal of Experimental Medicine. 209: 1901. DOI: 10.1084/jem.2011024220910c  0.36
2012 Delhase M, Kim SY, Lee H, Naiki-Ito A, Chen Y, Ahn ER, Murata K, Kim SJ, Lautsch N, Kobayashi KS, Shirai T, Karin M, Nakanishi M. TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2 (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 4 (E177-E186)) Proceedings of the National Academy of Sciences of the United States of America. 109: 4332-4335. DOI: 10.1073/pnas.1201576109  0.36
2011 Enzler T, Sano Y, Choo MK, Cottam HB, Karin M, Tsao H, Park JM. Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model. Cancer Discovery. 1: 496-507. PMID 22389871 DOI: 10.1158/2159-8290.CD-11-0143  0.36
2011 Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D. An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 147: 1233-47. PMID 22153071 DOI: 10.1016/J.Cell.2013.02.013  0.36
2011 Kuraishy A, Karin M, Grivennikov SI. Tumor promotion via injury- and death-induced inflammation. Immunity. 35: 467-77. PMID 22035839 DOI: 10.1016/j.immuni.2011.09.006  0.36
2011 Holzer RG, Park EJ, Li N, Tran H, Chen M, Choi C, Solinas G, Karin M. Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell. 147: 173-84. PMID 21962514 DOI: 10.1016/J.Cell.2011.08.034  0.36
2011 Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF, Karin M. Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation. The Journal of Experimental Medicine. 208: 1889-900. PMID 21825016 DOI: 10.1084/Jem.20110242  0.36
2011 Stebbins JL, De SK, Pavlickova P, Chen V, Machleidt T, Chen LH, Kuntzen C, Kitada S, Karin M, Pellecchia M. Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor. Journal of Medicinal Chemistry. 54: 6206-14. PMID 21815634 DOI: 10.1021/jm200479c  0.36
2011 Botti E, Spallone G, Moretti F, Marinari B, Pinetti V, Galanti S, De Meo PD, De Nicola F, Ganci F, Castrignanò T, Pesole G, Chimenti S, Guerrini L, Fanciulli M, Blandino G, ... Karin M, et al. Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 108: 13710-5. PMID 21807998 DOI: 10.1073/pnas.1110931108  0.36
2011 Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-κB as the matchmaker. Nature Immunology. 12: 715-23. PMID 21772280 DOI: 10.1038/ni.2060  0.36
2011 Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 35: 34-44. PMID 21683629 DOI: 10.1016/J.Immuni.2011.04.015  0.36
2011 Schmidt T, Kharabi Masouleh B, Loges S, Cauwenberghs S, Fraisl P, Maes C, Jonckx B, De Keersmaecker K, Kleppe M, Tjwa M, Schenk T, Vinckier S, Fragoso R, De Mol M, Beel K, ... ... Karin M, et al. Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Cancer Cell. 19: 740-53. PMID 21665148 DOI: 10.1016/J.Ccr.2011.05.007  0.36
2011 Häcker H, Tseng PH, Karin M. Expanding TRAF function: TRAF3 as a tri-faced immune regulator. Nature Reviews. Immunology. 11: 457-68. PMID 21660053 DOI: 10.1038/nri2998  0.36
2011 Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A. IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nature Communications. 2: 318. PMID 21587235 DOI: 10.1038/Ncomms1317  0.36
2011 Kang J, Jiang MH, Min HJ, Jo EK, Lee S, Karin M, Yune TY, Lee SJ. IKK-β-mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury. European Journal of Immunology. 41: 1266-77. PMID 21469085 DOI: 10.1002/eji.201040582  0.36
2011 Xu G, Lo YC, Li Q, Napolitano G, Wu X, Jiang X, Dreano M, Karin M, Wu H. Crystal structure of inhibitor of κB kinase β. Nature. 472: 325-30. PMID 21423167 DOI: 10.1038/nature09853  0.36
2011 Tan W, Zhang W, Strasner A, Grivennikov S, Cheng JQ, Hoffman RM, Karin M. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature. 470: 548-53. PMID 21326202 DOI: 10.1038/Nature09707  0.36
2011 Guma M, Ronacher LM, Firestein GS, Karin M, Corr M. JNK-1 deficiency limits macrophage-mediated antigen-induced arthritis. Arthritis and Rheumatism. 63: 1603-12. PMID 21305529 DOI: 10.1002/art.30271  0.36
2011 Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nature Immunology. 12: 144-50. PMID 21170027 DOI: 10.1038/Ni.1976  0.36
2011 Costanzo A, Spallone G, Karin M. NF-κB, IκB Kinase and Interacting Signal Networks in Squamous Cell Carcinomas Signaling Pathways in Squamous Cancer. 201-222. DOI: 10.1007/978-1-4419-7203-3_10  0.36
2010 Guma M, Kashiwakura J, Crain B, Kawakami Y, Beutler B, Firestein GS, Kawakami T, Karin M, Corr M. JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 107: 22122-7. PMID 21135226 DOI: 10.1073/Pnas.1016401107  0.36
2010 Kong SD, Zhang W, Lee JH, Brammer K, Lal R, Karin M, Jin S. Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release. Nano Letters. 10: 5088-92. PMID 21038917 DOI: 10.1021/Nl1033733  0.36
2010 Zhang W, Kater AP, Widhopf GF, Chuang HY, Enzler T, James DF, Poustovoitov M, Tseng PH, Janz S, Hoh C, Herschman H, Karin M, Kipps TJ. B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 107: 18956-60. PMID 20956327 DOI: 10.1073/Pnas.1013420107  0.36
2010 Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Research. 70: 7465-75. PMID 20841473 DOI: 10.1158/0008-5472.Can-10-1439  0.36
2010 Lee JH, Bodmer R, Bier E, Karin M. Sestrins at the crossroad between stress and aging. Aging. 2: 369-74. PMID 20606249 DOI: v2/n6/full/100157.html  0.36
2010 Yang J, Splittgerber R, Yull FE, Kantrow S, Ayers GD, Karin M, Richmond A. Conditional ablation of Ikkb inhibits melanoma tumor development in mice. The Journal of Clinical Investigation. 120: 2563-74. PMID 20530876 DOI: 10.1172/Jci42358  0.36
2010 Lee SY, Miller M, Cho JY, Song DJ, Karin M, Broide DH. Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation. International Immunopharmacology. 10: 906-12. PMID 20494824 DOI: 10.1016/j.intimp.2010.05.001  0.36
2010 Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, et al. Cancer and inflammation: promise for biologic therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 335-51. PMID 20386472 DOI: 10.1097/Cji.0B013E3181D32E74  0.36
2010 He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, Sieghart W, Peck-Radosavljevic M, Leffert HL, Karin M. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell. 17: 286-97. PMID 20227042 DOI: 10.1016/j.ccr.2009.12.048  0.36
2010 Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science (New York, N.Y.). 327: 1223-8. PMID 20203043 DOI: 10.1126/Science.1182228  0.36
2010 Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell. 17: 89-97. PMID 20129250 DOI: 10.1016/j.ccr.2009.12.008  0.36
2010 Jang PG, Namkoong C, Kang GM, Hur MW, Kim SW, Kim GH, Kang Y, Jeon MJ, Kim EH, Lee MS, Karin M, Baik JH, Park JY, Lee KU, Kim YB, et al. NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia. The Journal of Biological Chemistry. 285: 9706-15. PMID 20097762 DOI: 10.1074/jbc.M109.070706  0.36
2010 Shibata W, Takaishi S, Muthupalani S, Pritchard DM, Whary MT, Rogers AB, Fox JG, Betz KS, Kaestner KH, Karin M, Wang TC. Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia. Gastroenterology. 138: 1022-34.e1-10. PMID 19962981 DOI: 10.1053/J.Gastro.2009.11.054  0.36
2009 Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, ... ... Karin M, et al. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell. 16: 295-308. PMID 19800575 DOI: 10.1016/j.ccr.2009.08.021  0.36
2009 Enzler T, Kater AP, Zhang W, Widhopf GF, Chuang HY, Lee J, Avery E, Croce CM, Karin M, Kipps TJ. Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression. Blood. 114: 4469-76. PMID 19755673 DOI: 10.1182/Blood-2009-06-230169  0.36
2009 Guma M, Rius J, Duong-Polk KX, Haddad GG, Lindsey JD, Karin M. Genetic and pharmacological inhibition of JNK ameliorates hypoxia-induced retinopathy through interference with VEGF expression. Proceedings of the National Academy of Sciences of the United States of America. 106: 8760-5. PMID 19433784 DOI: 10.1073/pnas.0902659106  0.36
2009 Chu WM, Gong X, Li ZW, Takabayashi K, Ouyang HH, Chen Y, Chen DJ, Li GC, Karin M, Raz E. Retraction: DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA. Cell. 136: 565. PMID 19203587 DOI: 10.1016/j.cell.2009.01.022  0.36
2009 Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. The Journal of Biological Chemistry. 284: 862-71. PMID 19001420 DOI: 10.1074/Jbc.M804632200  0.36
2008 Wang H, Matsuzawa A, Brown SA, Zhou J, Guy CS, Tseng PH, Forbes K, Nicholson TP, Sheppard PW, Häcker H, Karin M, Vignali DA. Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 105: 20197-202. PMID 19091944 DOI: 10.1073/pnas.0810461105  0.36
2008 Stebbins JL, De SK, Machleidt T, Becattini B, Vazquez J, Kuntzen C, Chen LH, Cellitti JF, Riel-Mehan M, Emdadi A, Solinas G, Karin M, Pellecchia M. Identification of a new JNK inhibitor targeting the JNK-JIP interaction site. Proceedings of the National Academy of Sciences of the United States of America. 105: 16809-13. PMID 18922779 DOI: 10.1073/pnas.0805677105  0.36
2008 Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell. 135: 61-73. PMID 18854155 DOI: 10.1016/J.Cell.2008.07.043  0.36
2008 Cho IH, Hong J, Suh EC, Kim JH, Lee H, Lee JE, Lee S, Kim CH, Kim DW, Jo EK, Lee KE, Karin M, Lee SJ. Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain : a Journal of Neurology. 131: 3019-33. PMID 18819987 DOI: 10.1093/brain/awn230  0.36
2008 Descargues P, Sil AK, Karin M. IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer. The Embo Journal. 27: 2639-47. PMID 18818691 DOI: 10.1038/emboj.2008.196  0.36
2008 Bernassola F, Karin M, Ciechanover A, Melino G. The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell. 14: 10-21. PMID 18598940 DOI: 10.1016/J.Ccr.2008.06.001  0.36
2008 Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proceedings of the National Academy of Sciences of the United States of America. 105: 7803-8. PMID 18511561 DOI: 10.1073/Pnas.0802726105  0.36
2008 Fong CH, Bebien M, Didierlaurent A, Nebauer R, Hussell T, Broide D, Karin M, Lawrence T. An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. The Journal of Experimental Medicine. 205: 1269-76. PMID 18490491 DOI: 10.1084/jem.20080124  0.36
2008 Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 453: 807-11. PMID 18432192 DOI: 10.1038/Nature06905  0.36
2007 Drew D, Shimada E, Huynh K, Bergqvist S, Talwar R, Karin M, Ghosh G. Inhibitor kappaB kinase beta binding by inhibitor kappaB kinase gamma. Biochemistry. 46: 12482-90. PMID 17924664 DOI: 10.1021/Bi701137A  0.36
2007 Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, ... ... Karin M, et al. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell. 130: 918-31. PMID 17803913 DOI: 10.1016/J.Cell.2007.07.009  0.36
2007 Van Waes C, Yu M, Nottingham L, Karin M. Inhibitor-kappaB kinase in tumor promotion and suppression during progression of squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4956-9. PMID 17785544 DOI: 10.1158/1078-0432.CCR-07-1287  0.36
2007 Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. The Journal of Clinical Investigation. 117: 1175-83. PMID 17476347 DOI: 10.1172/JCI31537  0.36
2007 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/Jci30556  0.36
2007 Zaph C, Troy AE, Taylor BC, Berman-Booty LD, Guild KJ, Du Y, Yost EA, Gruber AD, May MJ, Greten FR, Eckmann L, Karin M, Artis D. Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature. 446: 552-6. PMID 17322906 DOI: 10.1038/Nature05590  0.36
2007 Kim S, Millet I, Kim HS, Kim JY, Han MS, Lee MK, Kim KW, Sherwin RS, Karin M, Lee MS. NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1913-8. PMID 17267600 DOI: 10.1073/Pnas.0610690104  0.36
2006 Lu Z, Serghides L, Patel SN, Degousee N, Rubin BB, Krishnegowda G, Gowda DC, Karin M, Kain KC. Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model. Journal of Immunology (Baltimore, Md. : 1950). 177: 6344-52. PMID 17056565 DOI: 10.4049/Jimmunol.177.9.6344  0.36
2006 Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 103: 10741-6. PMID 16818881 DOI: 10.1073/Pnas.0603509103  0.36
2006 Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, Nilsson A, Karin M, Kaufman RJ. Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. The Journal of Biological Chemistry. 281: 21458-68. PMID 16717090 DOI: 10.1074/Jbc.M603784200  0.36
2006 Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 124: 823-35. PMID 16497591 DOI: 10.1016/J.Cell.2006.02.016  0.36
2006 Guichard A, Park JM, Cruz-Moreno B, Karin M, Bier E. Anthrax lethal factor and edema factor act on conserved targets in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 103: 3244-9. PMID 16455799 DOI: 10.1073/pnas.0510748103  0.36
2006 Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, Kamps MP, Raz E, Wagner H, Häcker G, Mann M, Karin M. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature. 439: 204-7. PMID 16306937 DOI: 10.1038/Nature04369  0.36
2005 Broide DH, Lawrence T, Doherty T, Cho JY, Miller M, McElwain K, McElwain S, Karin M. Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proceedings of the National Academy of Sciences of the United States of America. 102: 17723-8. PMID 16317067 DOI: 10.1073/pnas.0509235102  0.36
2005 Ruocco MG, Maeda S, Park JM, Lawrence T, Hsu LC, Cao Y, Schett G, Wagner EF, Karin M. I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. The Journal of Experimental Medicine. 201: 1677-87. PMID 15897281 DOI: 10.1084/Jem.20042081  0.36
2005 Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 434: 1138-43. PMID 15858576 DOI: 10.1038/Nature03491  0.36
2005 Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science (New York, N.Y.). 307: 734-8. PMID 15692052 DOI: 10.1126/Science.1103685  0.36
2005 Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IKK-beta links inflammation to obesity-induced insulin resistance. Nature Medicine. 11: 191-8. PMID 15685170 DOI: 10.1038/Nm1185  0.36
2004 Park JM, Ng VH, Maeda S, Rest RF, Karin M. Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists. The Journal of Experimental Medicine. 200: 1647-55. PMID 15611291 DOI: 10.1084/Jem.20041215  0.36
2004 Drayton DL, Bonizzi G, Ying X, Liao S, Karin M, Ruddle NH. I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue. Journal of Immunology (Baltimore, Md. : 1950). 173: 6161-8. PMID 15528353 DOI: 10.4049/Jimmunol.173.10.6161  0.36
2004 Bonizzi G, Bebien M, Otero DC, Johnson-Vroom KE, Cao Y, Vu D, Jegga AG, Aronow BJ, Ghosh G, Rickert RC, Karin M. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. The Embo Journal. 23: 4202-10. PMID 15470505 DOI: 10.1038/Sj.Emboj.7600391  0.36
2004 Shen HM, Lin Y, Choksi S, Tran J, Jin T, Chang L, Karin M, Zhang J, Liu ZG. Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death. Molecular and Cellular Biology. 24: 5914-22. PMID 15199146 DOI: 10.1128/Mcb.24.13.5914-5922.2004  0.36
2004 Galijatovic A, Beaton D, Nguyen N, Chen S, Bonzo J, Johnson R, Maeda S, Karin M, Guengerich FP, Tukey RH. The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice. The Journal of Biological Chemistry. 279: 23969-76. PMID 15037607 DOI: 10.1074/Jbc.M400973200  0.36
2004 Hsu LC, Park JM, Zhang K, Luo JL, Maeda S, Kaufman RJ, Eckmann L, Guiney DG, Karin M. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature. 428: 341-5. PMID 15029200 DOI: 10.1038/Nature02405  0.36
2004 Ohazama A, Hu Y, Schmidt-Ullrich R, Cao Y, Scheidereit C, Karin M, Sharpe PT. A dual role for Ikk alpha in tooth development. Developmental Cell. 6: 219-27. PMID 14960276 DOI: 10.1016/S1534-5807(04)00024-3  0.36
2004 Amir RE, Haecker H, Karin M, Ciechanover A. Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase. Oncogene. 23: 2540-7. PMID 14676825 DOI: 10.1038/Sj.Onc.1207366  0.36
2003 Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Developmental Cell. 4: 521-33. PMID 12689591 DOI: 10.1016/S1534-5807(03)00094-7  0.36
2003 Chen S, Nguyen N, Tamura K, Karin M, Tukey RH. The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis. The Journal of Biological Chemistry. 278: 19526-33. PMID 12637498 DOI: 10.1074/Jbc.M300780200  0.36
2002 Shim J, Karin M. The control of mRNA stability in response to extracellular stimuli. Molecules and Cells. 14: 323-31. PMID 12521293  0.36
2002 Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. A central role for JNK in obesity and insulin resistance. Nature. 420: 333-6. PMID 12447443 DOI: 10.1038/Nature01137  0.36
2002 Makris C, Roberts JL, Karin M. The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation. Molecular and Cellular Biology. 22: 6573-81. PMID 12192055 DOI: 10.1128/MCB.22.18.6573-6581.2002  0.36
2002 Takanami-Ohnishi Y, Amano S, Kimura S, Asada S, Utani A, Maruyama M, Osada H, Tsunoda H, Irukayama-Tomobe Y, Goto K, Karin M, Sudo T, Kasuya Y. Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. The Journal of Biological Chemistry. 277: 37896-903. PMID 12138127 DOI: 10.1074/jbc.M207326200  0.36
2001 Karin M, Takahashi T, Kapahi P, Delhase M, Chen Y, Makris C, Rothwarf D, Baud V, Natoli G, Guido F, Li N. Oxidative stress and gene expression: the AP-1 and NF-kappaB connections. Biofactors (Oxford, England). 15: 87-9. PMID 12016332 DOI: 10.1002/Biof.5520150207  0.36
2001 Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science (New York, N.Y.). 293: 1673-7. PMID 11533494 DOI: 10.1126/Science.1061620  0.36
2001 Senftleben U, Cao Y, Xiao G, Greten FR, Krähn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun SC, Karin M. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science (New York, N.Y.). 293: 1495-9. PMID 11520989 DOI: 10.1126/Science.1062677  0.36
2001 Kim JK, Kim YJ, Fillmore JJ, Chen Y, Moore I, Lee J, Yuan M, Li ZW, Karin M, Perret P, Shoelson SE, Shulman GI. Prevention of fat-induced insulin resistance by salicylate. The Journal of Clinical Investigation. 108: 437-46. PMID 11489937 DOI: 10.1172/Jci11559  0.36
2001 Ojo-Amaize EA, Kapahi P, Kakkanaiah VN, Takahashi T, Shalom-Barak T, Cottam HB, Adesomoju AA, Nchekwube EJ, Oyemade OA, Karin M, Okogun JI. Hypoestoxide, a novel anti-inflammatory natural diterpene, inhibits the activity of IkappaB kinase. Cellular Immunology. 209: 149-57. PMID 11446747 DOI: 10.1006/Cimm.2001.1798  0.36
2001 Cavalli V, Vilbois F, Corti M, Marcote MJ, Tamura K, Karin M, Arkinstall S, Gruenberg J. The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. Molecular Cell. 7: 421-32. PMID 11239470 DOI: 10.1016/S1097-2765(01)00189-7  0.36
2001 Feng W, Webb P, Nguyen P, Liu X, Li J, Karin M, Kushner PJ. Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway Molecular Endocrinology. 15: 32-45. PMID 11145737 DOI: 10.1210/MEND.15.1.0590  0.36
2000 Kapahi P, Takahashi T, Natoli G, Adams SR, Chen Y, Tsien RY, Karin M. Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase. The Journal of Biological Chemistry. 275: 36062-6. PMID 10967126 DOI: 10.1074/Jbc.M007204200  0.36
2000 Spence J, Gali RR, Dittmar G, Sherman F, Karin M, Finley D. Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain Cell. 102: 67-76. PMID 10929714 DOI: 10.1016/S0092-8674(00)00011-8  0.36
2000 Xia Y, Makris C, Su B, Li E, Yang J, Nemerow GR, Karin M. MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration Proceedings of the National Academy of Sciences of the United States of America. 97: 5243-5248. PMID 10805784 DOI: 10.1073/Pnas.97.10.5243  0.36
2000 Wu Z, Woodring PJ, Bhakta KS, Tamura K, Wen F, Feramisco JR, Karin M, Wang JY, Puri PL. p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Molecular and Cellular Biology. 20: 3951-64. PMID 10805738 DOI: 10.1128/Mcb.20.11.3951-3964.2000  0.36
2000 Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J, Feramisco JR, Karin M, Wang JY. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes & Development. 14: 574-84. PMID 10716945 DOI: 10.1101/Gad.14.5.574  0.36
2000 Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, Santoro MG. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature. 403: 103-8. PMID 10638762 DOI: 10.1038/47520  0.36
1999 Zandi E, Karin M. Bridging the gap: Composition, regulation, and physiological function of the IκB kinase complex Molecular and Cellular Biology. 19: 4547-4551. PMID 10373503 DOI: 10.1128/Mcb.19.7.4547  0.36
1999 Hettmann T, DiDonato J, Karin M, Leiden JM. An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. The Journal of Experimental Medicine. 189: 145-58. PMID 9874571 DOI: 10.1084/jem.189.1.145  0.36
1998 Rothwarf DM, Zandi E, Natoli G, Karin M. IKK-γ is an essential regulatory subunit of the IκB kinase complex Nature. 395: 297-300. PMID 9751060 DOI: 10.1038/26261  0.36
1998 Zandi E, Chen Y, Karin M. Direct phosphorylation of IκB by IKKα and IKKβ: Discrimination between free and NF-κB-bound substrate Science. 281: 1360-1363. PMID 9721103 DOI: 10.1126/Science.281.5381.1360  0.36
1998 Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M, Sun SC. NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I tax-mediated NF-κB activation Journal of Biological Chemistry. 273: 21132-21136. PMID 9694868 DOI: 10.1074/Jbc.273.33.21132  0.36
1997 Minden A, Karin M. Regulation and function of the JNK subgroup of MAP kinases Biochimica Et Biophysica Acta - Reviews On Cancer. 1333. PMID 9395283 DOI: 10.1016/S0304-419X(97)00018-8  0.36
1997 Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for Iκb phosphorylation and NF-κB activation Cell. 91: 243-252. PMID 9346241 DOI: 10.1016/S0092-8674(00)80406-7  0.36
1997 Didonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB Nature. 388: 548-554. PMID 9252186 DOI: 10.1038/41493  0.36
1997 Saatcioglu F, Lopez G, West BL, Zandi E, Feng W, Lu H, Esmaili A, Apriletti JW, Kushner PJ, Baxter JD, Karin M. Mutations in the conserved C-terminal sequence in thyroid hormone receptor dissociate hormone-dependent activation from interference with AP-1 activity. Molecular and Cellular Biology. 17: 4687-95. PMID 9234725 DOI: 10.1128/Mcb.17.8.4687  0.36
1997 Aronheim A, Zandi E, Hennemann H, Elledge SJ, Karin M. Isolation of an AP-1 repressor by a novel method for detecting protein- protein interactions Molecular and Cellular Biology. 17: 3094-3102. PMID 9154808 DOI: 10.1128/Mcb.17.6.3094  0.36
1997 Karin M, Liu ZG, Zandi E. AP-1 function and regulation Current Opinion in Cell Biology. 9: 240-246. PMID 9069263 DOI: 10.1016/S0955-0674(97)80068-3  0.36
1996 Collins LR, Minden A, Karin M, Brown JH. Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac. The Journal of Biological Chemistry. 271: 17349-53. PMID 8663428 DOI: 10.1074/jbc.271.29.17349  0.36
1996 Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. The Journal of Biological Chemistry. 271: 3229-37. PMID 8621725 DOI: 10.1074/Jbc.271.6.3229  0.36
1996 Dixon WJ, Inouye C, Karin M, Tullius TD. CUP2 binds in a bipartite manner to upstream activation sequence c in the promoter of the yeast copper metallothionein gene Journal of Biological Inorganic Chemistry. 1: 451-459. DOI: 10.1007/S007750050078  0.36
1995 White MA, Nicolette C, Minden A, Polverino A, Van Aelst L, Karin M, Wigler MH. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80: 533-41. PMID 7867061 DOI: 10.1016/0092-8674(95)90507-3  0.36
1995 Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M. Identification of a dual specificity kinase that activates the jun kinases and p38-Mpk2 Science. 268: 286-290. PMID 7716521 DOI: 10.1126/Science.7716521  0.36
1995 Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs Cell. 81: 1147-1157. PMID 7600582 DOI: 10.1016/S0092-8674(05)80019-4  0.36
1994 Engelberg D, Klein C, Martinetto H, Struhl K, Karin M. The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals Cell. 77: 381-390. PMID 8181058 DOI: 10.1016/0092-8674(94)90153-8  0.36
1994 Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370: 226-9. PMID 8028671 DOI: 10.1038/370226A0  0.36
1994 Westwick JK, Cox AD, Der CJ, Cobb MH, Hibi M, Karin M, Brenner DA. Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases Proceedings of the National Academy of Sciences of the United States of America. 91: 6030-6034. PMID 8016110 DOI: 10.1073/Pnas.91.13.6030  0.36
1994 Engelberg D, Zandi E, Parker CS, Karin M. The yeast and mammalian Ras pathways control transcription of heat shock genes independently of heat shock transcription factor. Molecular and Cellular Biology. 14: 4929-37. PMID 8007989 DOI: 10.1128/Mcb.14.7.4929  0.36
1994 Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK Science. 266: 1719-1723. PMID 7992057 DOI: 10.1126/Science.7992057  0.36
1994 Minden A, Lin A, Smeal T, Dérijard B, Cobb M, Davis R, Karin M. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases Molecular and Cellular Biology. 14: 6683-6688. PMID 7935387 DOI: 10.1128/Mcb.14.10.6683  0.36
1993 Alberts AS, Deng T, Lin A, Meinkoth JL, Schönthal A, Mumby MC, Karin M, Feramisco JR. Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Molecular and Cellular Biology. 13: 2104-12. PMID 8384305 DOI: 10.1128/Mcb.13.4.2104  0.36
1993 Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain Genes and Development. 7: 2135-2148. PMID 8224842 DOI: 10.1101/Gad.7.11.2135  0.36
1993 Lew D, Brady H, Klausing K, Yaginuma K, Theill LE, Stauber C, Karin M, Mellon PL. GHF-1 - promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice Genes and Development. 7: 683-693. PMID 8096199 DOI: 10.1101/Gad.7.4.683  0.36
1992 Trejo J, Chambard JC, Karin M, Brown JH. Biphasic Increase in c-jun mRNA Is Required for Induction of AP-1-Mediated Gene Transcription: Differential Effects of Muscarinic and Thrombin Receptor Activation Molecular and Cellular Biology. 12: 4742-4750. PMID 1328861 DOI: 10.1128/Mcb.12.10.4742  0.36
1990 Buchman C, Skroch P, Dixon W, Tullius TD, Karin M. A single amino acid change in CUP2 alters its mode of DNA binding Molecular and Cellular Biology. 10: 4778-4787. PMID 2167439 DOI: 10.1128/Mcb.10.9.4778  0.36
1990 Dollé P, Castrillo JL, Theill LE, Deerinck T, Ellisman M, Karin M. Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activity Cell. 60: 809-820. PMID 1690079 DOI: 10.1016/0092-8674(90)90095-V  0.36
1988 Harrington MA, Jones PA, Imagawa M, Karin M. Cytosine methylation does not affect binding of transcription factor Sp1 Proceedings of the National Academy of Sciences of the United States of America. 85: 2066-2070. PMID 3281160 DOI: 10.1073/Pnas.85.7.2066  0.36
1985 Le Beau MM, Diaz MO, Karin M, Rowley JD. Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia Nature. 313: 709-711. PMID 3856101 DOI: 10.1038/313709a0  0.36
1984 Karin M, Eberhardt NL, Mellon SH, Malich N, Richards RI, Slater EP, Barta A, Martial JA, Baxter JD, Cathala G. Expression and hormonal regulation of the rat growth hormone gene in transfected mouse L cells. Dna (Mary Ann Liebert, Inc.). 3: 147-55. PMID 6723496  0.36
1983 Welch JW, Fogel S, Cathala G, Karin M. Industrial yeasts display tandem gene iteration at the CUP1 region Molecular and Cellular Biology. 3: 1353-1361. PMID 6621529 DOI: 10.1128/MCB.3.8.1353  0.36
1983 Cathala G, Savouret JF, Mendez B, West BL, Karin M, Martial JA, Baxter JD. A method for isolation of intact, translationally active ribonucleic acid. Dna (Mary Ann Liebert, Inc.). 2: 329-35. PMID 6198133  0.36
1983 Fogel S, Welch JW, Cathala G, Karin M. Gene amplification in yeast: CUP1 copy number regulates copper resistance Current Genetics. 7: 347-355. DOI: 10.1007/BF00445874  0.36
1981 Karin M, Andersen RD, Herschman HR. Induction of metallothionein mRNA in HeLa cells by dexamethasone and by heavy metals. European Journal of Biochemistry / Febs. 118: 527-31. PMID 7297561 DOI: 10.1111/J.1432-1033.1981.Tb05551.X  0.92
1981 Karin M, Herschman HR. Induction of metallothionein in HeLa cells by dexamethasone and zinc. European Journal of Biochemistry / Febs. 113: 267-72. PMID 7202410 DOI: 10.1111/J.1432-1033.1981.Tb05062.X  0.92
1981 Karin M, Slater EP, Herschman HR. Regulation of metallothionein synthesis in HeLa cells by heavy metals and glucocorticoids. Journal of Cellular Physiology. 106: 63-74. PMID 6162854 DOI: 10.1002/Jcp.1041060108  0.92
1980 Karin M, Herschman HR. Glucocorticoid hormone receptor mediated induction of metallothionein synthesis in HeLa cells. Journal of Cellular Physiology. 103: 35-40. PMID 7430258 DOI: 10.1002/Jcp.1041030106  0.92
1980 Karin M, Andersen RD, Slater E, Smith K, Herschman HR. Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response. Nature. 286: 295-7. PMID 7402316 DOI: 10.1038/286295A0  0.92
1980 Karin M, Herschman HR. Characterization of the metallothioneins induced in HeLa cells by dexamethasone and zinc. European Journal of Biochemistry / Febs. 107: 395-401. PMID 7398649 DOI: 10.1111/J.1432-1033.1980.Tb06042.X  0.92
1980 Karin M, Herschman HR, Weinstein D. Primary induction of metallothionein by dexamethasone in culture rat hepatocytes. Biochemical and Biophysical Research Communications. 92: 1052-69. PMID 7362599 DOI: 10.1016/0006-291X(80)90808-6  0.92
1979 Karin M, Herschman HR. Dexamethasone stimulation of metallothionein synthesis in HeLa cell cultures. Science (New York, N.Y.). 204: 176-7. PMID 432639 DOI: 10.1126/Science.432639  0.92
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