Year |
Citation |
Score |
2008 |
Lu T, Rubio ME, Trussell LO. Glycinergic transmission shaped by the corelease of GABA in a mammalian auditory synapse. Neuron. 57: 524-35. PMID 18304482 DOI: 10.1016/j.neuron.2007.12.010 |
0.54 |
|
2007 |
Lu T, Trussell LO. Development and elimination of endbulb synapses in the chick cochlear nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 808-17. PMID 17251420 DOI: 10.1523/JNEUROSCI.4871-06.2007 |
0.535 |
|
2000 |
Lu T, Trussell LO. Inhibitory transmission mediated by asynchronous transmitter release. Neuron. 26: 683-94. PMID 10896163 DOI: 10.1016/S0896-6273(00)81204-0 |
0.536 |
|
Low-probability matches (unlikely to be authored by this person) |
2019 |
Jiang F, Wei Q, Li H, Li H, Cui Y, Ma Y, Chen H, Cao P, Lu T, Chen Y. Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies. Bioorganic & Medicinal Chemistry. 115181. PMID 31767403 DOI: 10.1016/j.bmc.2019.115181 |
0.137 |
|
1998 |
Lu T, Shen Y, Yang XL. Desensitization of AMPA receptors on horizontal cells isolated from crucian carp retina Neuroscience Research. 31: 123-135. PMID 9700718 DOI: 10.1016/S0168-0102(98)00031-5 |
0.13 |
|
2021 |
Li Y, Ren BX, Li HM, Lu T, Fu R, Wu ZQ. Omeprazole suppresses aggressive cancer growth and metastasis in mice through promoting Snail degradation. Acta Pharmacologica Sinica. PMID 34785782 DOI: 10.1038/s41401-021-00787-1 |
0.13 |
|
2019 |
Zhang Y, Zhang M, Wang Y, Fan Y, Chen X, Yang Y, Hua Y, Xie W, Lu T, Tang W, Chen Y, Liu H. Protein-Ligand Interaction Guided Discovery of Novel VEGFR-2 Inhibitors. Journal of Biomolecular Structure & Dynamics. 1-18. PMID 31232191 DOI: 10.1080/07391102.2019.1635915 |
0.127 |
|
2023 |
Sui Q, Hu Z, Liang J, Lu T, Bian Y, Jin X, Li M, Huang Y, Yang H, Wang Q, Lin Z, Chen Z, Zhan C. Targeting TAM-secreted S100A9 effectively enhances the tumor-suppressive effect of metformin in treating lung adenocarcinoma. Cancer Letters. 216497. PMID 38008395 DOI: 10.1016/j.canlet.2023.216497 |
0.125 |
|
2017 |
Lu T, Zhu Y, Xu J, Ke M, Zhang M, Tan C, Fu Z, Qian H. Evaluation of the toxic response induced by azoxystrobin in the non-target green alga Chlorella pyrenoidosa. Environmental Pollution (Barking, Essex : 1987). 234: 379-388. PMID 29202416 DOI: 10.1016/j.envpol.2017.11.081 |
0.123 |
|
2023 |
Cui B, Wang Y, Zhao Z, Fan L, Jiao Y, Li H, Feng J, Tang W, Lu T, Chen Y. Discovery of 3-(1H-benzo[d]imidazole-2-yl)-1H-pyrazol-4 -amine derivatives as novel and potent syk inhibitors for the treatment of hematological malignancies. European Journal of Medicinal Chemistry. 258: 115597. PMID 37423126 DOI: 10.1016/j.ejmech.2023.115597 |
0.123 |
|
2021 |
Lu T, Li M, Zhao M, Huang Y, Bi G, Liang J, Chen Z, Zheng Y, Xi J, Lin Z, Zhan C, Jiang W, Wang Q, Tan L. Metformin inhibits human non-small cell lung cancer by regulating AMPK-CEBPB-PDL1 signaling pathway. Cancer Immunology, Immunotherapy : Cii. PMID 34837101 DOI: 10.1007/s00262-021-03116-x |
0.123 |
|
2023 |
Hu C, Zu D, Xu J, Xu H, Yuan L, Chen J, Wei Q, Zhang Y, Han J, Lu T, Dong J, Qin JJ, Xu Z, Cheng X. Polyphyllin B Suppresses Gastric Tumor Growth by Modulating Iron Metabolism and Inducing Ferroptosis. International Journal of Biological Sciences. 19: 1063-1079. PMID 36923926 DOI: 10.7150/ijbs.80324 |
0.123 |
|
2022 |
Fang X, Liu C, Zhang K, Yang W, Wu Z, Shen S, Ma Y, Lu X, Chen Y, Lu T, Hu Q, Jiang Y. Discovery of orally active 1,4,5,6,8-pentaazaacenaphthylens as novel, selective, and potent covalent BTK inhibitors for the treatment of rheumatoid arthritis. European Journal of Medicinal Chemistry. 246: 114940. PMID 36462441 DOI: 10.1016/j.ejmech.2022.114940 |
0.123 |
|
2020 |
Song J, Zhu Y, Zu W, Duan C, Xu J, Jiang F, Wang X, Li S, Liu C, Gao Q, Li H, Zhang Y, Tang W, Lu T, Chen Y. The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth. Bioorganic & Medicinal Chemistry. 115856. PMID 33199201 DOI: 10.1016/j.bmc.2020.115856 |
0.123 |
|
2016 |
Zeng X, Liu L, Zheng M, Sun H, Xiao J, Lu T, Huang G, Chen P, Zhang J, Zhu F, Li H, Duan Q. Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase. Oncotarget. PMID 26967058 DOI: 10.18632/oncotarget.7984 |
0.123 |
|
2018 |
Heng H, Zhi Y, Yuan H, Wang Z, Li H, Wang S, Tian J, Liu H, Chen Y, Lu T, Ran T, Lu S. Discovery of a highly selective FLT3 inhibitor with specific proliferation inhibition against AML cells harboring FLT3-ITD mutation. European Journal of Medicinal Chemistry. 163: 195-206. PMID 30508668 DOI: 10.1016/j.ejmech.2018.11.063 |
0.122 |
|
2023 |
Chen J, Liu X, Zhao S, Chen H, Lu T, Wang J, Han J, Wu W, Shen X, Li C. Carboxymethylated Alginate-Resiquimod Micelles Reverse the Immunosuppressive Tumor Microenvironment and Synergistically Enhance the Chemotherapy and Immunotherapy for Gastric Cancer. Acs Applied Materials & Interfaces. PMID 37477904 DOI: 10.1021/acsami.3c06828 |
0.122 |
|
2022 |
Jiang L, Liu Y, Su X, Wang J, Zhao Y, Tumbath S, Kilgore JA, Williams NS, Chen Y, Wang X, Mendonca MS, Lu T, Fu YX, Huang X. KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib Inhibiting FOXO3a/GADD45α Pathway. Frontiers in Oncology. 12: 976292. PMID 36203459 DOI: 10.3389/fonc.2022.976292 |
0.121 |
|
2023 |
Qian X, Dai X, Luo L, Lin M, Xu Y, Zhao Y, Huang D, Qiu H, Liang L, Liu H, Liu Y, Gu L, Lu T, Chen Y, Zhang Y. An Interpretable Multitask Framework BiLAT Enables Accurate Prediction of Cyclin-Dependent Protein Kinase Inhibitors. Journal of Chemical Information and Modeling. PMID 37171216 DOI: 10.1021/acs.jcim.3c00473 |
0.12 |
|
2023 |
Zhang H, Liang J, Lu T, Li M, Shan G, Bi G, Zhao M, Jin X, Wang Q, Chen Z, Zhan C. AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target. Pharmacological Research. 106819. PMID 37321467 DOI: 10.1016/j.phrs.2023.106819 |
0.12 |
|
2024 |
Yang Y, Xu N, Zhang Z, Lei C, Chen B, Qin G, Qiu D, Lu T, Qian H. Deciphering Microbial Community and Nitrogen Fixation in the Legume Rhizosphere. Journal of Agricultural and Food Chemistry. PMID 38442360 DOI: 10.1021/acs.jafc.3c09160 |
0.12 |
|
2024 |
Zhou X, Li Y, Pan M, Lu T, Liu C, Wang Z, Tang F, Hu G. PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research. Diagnostic Pathology. 19: 48. PMID 38431604 DOI: 10.1186/s13000-024-01474-5 |
0.12 |
|
2024 |
Hu Z, Sui Q, Jin X, Shan G, Huang Y, Yi Y, Zeng D, Zhao M, Zhan C, Wang Q, Lin Z, Lu T, Chen Z. IL6-STAT3-C/EBPβ-IL6 positive feedback loop in tumor-associated macrophages promotes the EMT and metastasis of lung adenocarcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 43: 63. PMID 38424624 DOI: 10.1186/s13046-024-02989-x |
0.12 |
|
2024 |
Xu M, Zhong W, Yang C, Liu M, Yuan X, Lu T, Li D, Zhang G, Liu H, Zeng Y, Yang X, Zhou Y, Zhou L. Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 127: 155392. PMID 38412575 DOI: 10.1016/j.phymed.2024.155392 |
0.12 |
|
2024 |
Li H, Chai L, Pu H, Yin LL, Li M, Zhang X, Liu YS, Pang MH, Lu T. T2WI-based MRI radiomics for the prediction of preoperative extranodal extension and prognosis in resectable rectal cancer. Insights Into Imaging. 15: 57. PMID 38411722 DOI: 10.1186/s13244-024-01625-8 |
0.12 |
|
2024 |
Wang Z, Lu X, Liu C, Huang F, Lu T, Chen Y, Liu L, Lu S. Discovery of FLT3-targeting PROTACs with potent antiproliferative activity against acute myeloid leukemia cells harboring FLT3 mutations. European Journal of Medicinal Chemistry. 268: 116237. PMID 38387337 DOI: 10.1016/j.ejmech.2024.116237 |
0.12 |
|
2024 |
Wang Q, Han XL, Shen JQ, Lai JD, Zhang CL, Fang ZQ, Lu T. sp. nov., a bacterium isolated from mountain soil in the habitat of . International Journal of Systematic and Evolutionary Microbiology. 74. PMID 38334269 DOI: 10.1099/ijsem.0.006260 |
0.12 |
|
2023 |
Wang Z, Wu D, Zhao X, Liu C, Jia S, He Q, Huang F, Cheng Z, Lu T, Chen Y, Chen Y, Yang P, Lu S. Rational discovery of dual FLT3/HDAC inhibitors as a potential AML therapy. European Journal of Medicinal Chemistry. 260: 115759. PMID 37659198 DOI: 10.1016/j.ejmech.2023.115759 |
0.12 |
|
2020 |
Li HM, Bi YR, Li Y, Fu R, Lv WC, Jiang N, Xu Y, Ren BX, Chen YD, Xie H, Wang S, Lu T, Wu ZQ. A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer. Science Advances. 6: eaaw8500. PMID 32494626 DOI: 10.1126/sciadv.aaw8500 |
0.12 |
|
2023 |
Liu L, Zhang L, Chen X, Yang K, Cui H, Qian R, Zhao S, Wang L, Su X, Zhao M, Wang M, Hu Z, Lu T, Zhu Y, Zhou QQ, et al. Design and synthesis of 1H-benzo[d]imidazole selective HDAC6 inhibitors with potential therapy for multiple myeloma. European Journal of Medicinal Chemistry. 261: 115833. PMID 37797564 DOI: 10.1016/j.ejmech.2023.115833 |
0.12 |
|
2023 |
Zhao M, Lu T, Bi G, Hu Z, Liang J, Bian Y, Feng M, Zhan C. PLK1 regulating chemoradiotherapy sensitivity of esophageal squamous cell carcinoma through pentose phosphate pathway/ferroptosis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 168: 115711. PMID 37879213 DOI: 10.1016/j.biopha.2023.115711 |
0.119 |
|
2019 |
Heng H, Wang Z, Li H, Huang Y, Lan Q, Guo X, Zhang L, Zhi Y, Cai J, Qin T, Xiang L, Wang S, Chen Y, Lu T, Lu S. Combining structure- and property-based optimization to identify selective FLT3-ITD inhibitors with good antitumor efficacy in AML cell inoculated mouse xenograft model. European Journal of Medicinal Chemistry. 176: 248-267. PMID 31103903 DOI: 10.1016/j.ejmech.2019.05.021 |
0.119 |
|
2020 |
Zhang Y, Li Y, Wang X, Qu R, Li J, Li T, He T, Wang Z, Liu Y, Shao X, Lu T. Herbal plants coordinate COVID-19 in multiple dimensions - An insight analysis for clinically applied remedies. International Journal of Medical Sciences. 17: 3125-3145. PMID 33173434 DOI: 10.7150/ijms.50260 |
0.119 |
|
2023 |
Zhang W, Zhao S, Luo Y, Zhang Y, Feng Y, Tang F, Zhou X, Peng S, Fan Y, Xie S, Li H, Lai Q, Fu L, Luo Y, Pei S, ... ... Lu T, et al. Discovery of (2)--(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment. Journal of Medicinal Chemistry. PMID 38128906 DOI: 10.1021/acs.jmedchem.3c01417 |
0.118 |
|
2008 |
Dasgupta M, Agarwal MK, Varley P, Lu T, Stark GR, Kandel ES. Transposon-based mutagenesis identifies short RIP1 as an activator of NFkappaB. Cell Cycle (Georgetown, Tex.). 7: 2249-56. PMID 18635966 DOI: 10.4161/cc.7.14.6310 |
0.118 |
|
2022 |
Cui H, Hu Z, Yang K, Huang J, Wu Y, Chen Q, Wei R, Wang P, Wang H, Li H, Chen Y, Lu T, Yao Y, Zhu Y. Design and synthesis of highly TRAIL expression HDAC inhibitors based on ONC201 to promote apoptosis of colorectal cancer. European Journal of Medicinal Chemistry. 238: 114484. PMID 35649291 DOI: 10.1016/j.ejmech.2022.114484 |
0.118 |
|
2020 |
Zhang M, Fang X, Wang C, Hua Y, Huang C, Wang M, Zhu L, Wang Z, Gao Y, Zhang T, Liu H, Zhang Y, Lu S, Lu T, Chen Y, et al. Design and synthesis of 1H-indazole-3-carboxamide derivatives as potent and selective PAK1 inhibitors with anti-tumour migration and invasion activities. European Journal of Medicinal Chemistry. 203: 112517. PMID 32846314 DOI: 10.1016/j.ejmech.2020.112517 |
0.117 |
|
2020 |
Xu J, Li H, Wang X, Huang J, Li S, Liu C, Dong R, Zhu G, Duan C, Jiang F, Zhang Y, Zhu Y, Zhang T, Chen Y, Tang W, ... Lu T, et al. Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity. European Journal of Medicinal Chemistry. 200: 112424. PMID 32447197 DOI: 10.1016/j.ejmech.2020.112424 |
0.117 |
|
2016 |
Vishchuk OS, Sun H, Wang Z, Ermakova SP, Xiao J, Lu T, Xue P, Zvyagintseva TN, Xiong H, Shao C, Yan W, Duan Q, Zhu F. PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth. Oncotarget. PMID 26936995 DOI: 10.18632/oncotarget.7708 |
0.117 |
|
2022 |
Wang Z, Ren J, Jia K, Zhao Y, Liang L, Cheng Z, Huang F, Zhao X, Cheng J, Song S, Sheng T, Wan W, Shu Q, Wu D, Zhang J, ... Lu T, et al. Identification and structural analysis of a selective tropomyosin receptor kinase C (TRKC) inhibitor. European Journal of Medicinal Chemistry. 241: 114601. PMID 35872544 DOI: 10.1016/j.ejmech.2022.114601 |
0.117 |
|
2012 |
Liu YQ, Hu XY, Lu T, Cheng YN, Young CYF, Yuan HQ, Lou HX. Retigeric Acid b exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo Plos One. 7. PMID 22666431 DOI: 10.1371/journal.pone.0038000 |
0.117 |
|
2015 |
Prabhu L, Hartley AV, Martin M, Warsame F, Sun E, Lu T. Role of post-translational modification of the Y box binding protein 1 in human cancers. Genes & Diseases. 2: 240-246. PMID 30258867 DOI: 10.1016/j.gendis.2015.05.001 |
0.116 |
|
2017 |
Wang L, Zhu G, Zhang Q, Duan C, Zhang Y, Zhang Z, Zhou Y, Lu T, Tang W. Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance. Organic & Biomolecular Chemistry. PMID 28368067 DOI: 10.1039/c7ob00518k |
0.116 |
|
2021 |
Hou S, Yang X, Yang Y, Tong Y, Chen Q, Wan B, Wei R, Lu T, Chen Y, Hu Q. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. European Journal of Medicinal Chemistry. 220: 113482. PMID 33906048 DOI: 10.1016/j.ejmech.2021.113482 |
0.116 |
|
2017 |
Wang L, Zhang Q, Zhu G, Zhang Z, Zhi Y, Zhang L, Mao T, Zhou X, Chen Y, Lu T, Tang W. Design, synthesis and evaluation of derivatives based on pyrimidine scaffold as potent Pan-Raf inhibitors to overcome resistance. European Journal of Medicinal Chemistry. 130: 86-106. PMID 28242553 DOI: 10.1016/j.ejmech.2017.02.041 |
0.116 |
|
2009 |
Lu T, Jackson MW, Singhi AD, Kandel ES, Yang M, Zhang Y, Gudkov AV, Stark GR. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proceedings of the National Academy of Sciences of the United States of America. 106: 16339-44. PMID 19805303 DOI: 10.1073/Pnas.0908560106 |
0.116 |
|
2015 |
Liu HC, Tang SZ, Lu S, Ran T, Wang J, Zhang YM, Xu AY, Lu T, Chen YD. Studies on [5,6]-Fused Bicyclic Scaffolds Derivatives as Potent Dual B-Raf(V600E)/KDR Inhibitors Using Docking and 3D-QSAR Approaches. International Journal of Molecular Sciences. 16: 24451-24474. PMID 26501259 DOI: 10.3390/ijms161024451 |
0.115 |
|
2018 |
Shi ZH, Liu FT, Tian HZ, Zhang YM, Li NG, Lu T. Design, synthesis and structure-activity relationship of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure as multi-target inhibitors against receptor tyrosine kinase. Bioorganic & Medicinal Chemistry. PMID 30121211 DOI: 10.1016/j.bmc.2018.08.013 |
0.113 |
|
2006 |
Newman RA, Yang P, Hittelman WN, Lu T, Ho DH, Ni D, Chan D, Vijjeswarapu M, Cartwright C, Dixon S, Felix E, Addington C. Oleandrin-mediated oxidative stress in human melanoma cells. Journal of Experimental Therapeutics & Oncology. 5: 167-81. PMID 16528968 |
0.113 |
|
2023 |
Duan Y, Cheng H, Zhuang L, Xia J, Xu Y, Zhang R, Sun R, Lu T, Chen Y. Discovery of Thieno[3,2-d]pyrimidine derivatives as potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) kinase. European Journal of Medicinal Chemistry. 255: 115370. PMID 37130473 DOI: 10.1016/j.ejmech.2023.115370 |
0.112 |
|
2022 |
Lin W, Zhang Z, Chen Y, Zhang Q, Ke M, Lu T, Qian H. The mechanism of different cyanobacterial responses to glyphosate. Journal of Environmental Sciences (China). 125: 258-265. PMID 36375911 DOI: 10.1016/j.jes.2021.11.039 |
0.112 |
|
2012 |
Zhang Y, Liu H, Jiao Y, Yuan H, Wang F, Lu S, Yao S, Ke Z, Tai W, Jiang Y, Chen Y, Lu T. De novo design of N-(pyridin-4-ylmethyl)aniline derivatives as KDR inhibitors: 3D-QSAR, molecular fragment replacement, protein-ligand interaction fingerprint, and ADMET prediction. Molecular Diversity. 16: 787-802. PMID 23090418 DOI: 10.1007/s11030-012-9405-y |
0.112 |
|
2020 |
Hou S, Yang X, Tong Y, Yang Y, Chen Q, Wan B, Wei R, Wang Y, Zhang Y, Kong B, Huang J, Chen Y, Lu T, Hu Q, Du D. Structure-based discovery of 1H-indole-2-carboxamide derivatives as potent ASK1 inhibitors for potential treatment of ulcerative colitis. European Journal of Medicinal Chemistry. 211: 113114. PMID 33360793 DOI: 10.1016/j.ejmech.2020.113114 |
0.112 |
|
2022 |
Wang X, Liu X, Huang J, Liu C, Li H, Wang C, Hong Q, Lei Y, Xia J, Yu Z, Dong R, Xu J, Tu Z, Duan C, Li S, ... Lu T, et al. Discovery of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as potent and selective CDK9 inhibitors that enable transient target engagement for the treatment of hematologic malignancies. European Journal of Medicinal Chemistry. 238: 114461. PMID 35605362 DOI: 10.1016/j.ejmech.2022.114461 |
0.111 |
|
2017 |
Zhang Y, Wang L, Zhang Q, Zhu G, Zhang Z, Xiang Z, Chen Y, Lu T, Tang W. Potent Pan-Raf and RTKs inhibitors based on cyclopropyl formamide fragment overcome resistance. Journal of Chemical Information and Modeling. PMID 28485964 DOI: 10.1021/acs.jcim.6b00795 |
0.111 |
|
2017 |
Lu T, Kim P, Luo Y. Tp53 gene mediates distinct dopaminergic neuronal damage in different dopaminergic neurotoxicant models. Neural Regeneration Research. 12: 1413-1417. PMID 29089978 DOI: 10.4103/1673-5374.215243 |
0.111 |
|
2020 |
Hartley AV, Lu T. Modulating the modulators: regulation of protein arginine methyltransferases by post-translational modifications. Drug Discovery Today. PMID 32629172 DOI: 10.1016/j.drudis.2020.06.031 |
0.111 |
|
2019 |
Liu FT, Li NG, Zhang YM, Xie WC, Yang SP, Lu T, Shi ZH. Recent advance in the development of novel, selective and potent FGFR inhibitors. European Journal of Medicinal Chemistry. 111884. PMID 31761386 DOI: 10.1016/j.ejmech.2019.111884 |
0.111 |
|
2023 |
Wang Z, Yin L, Xiong Z, Huang F, Yang N, Jiang F, Li H, Cui Y, Ren J, Cheng Z, Jia K, Lu T, Zhu J, Hu Q, Chen Y. Discovery of a Bromodomain and Extra Terminal Domain (BET) Inhibitor with the Selectivity for the Second Bromodomain (BD2) and the Capacity for the Treatment of Inflammatory Diseases. Journal of Medicinal Chemistry. PMID 37478496 DOI: 10.1021/acs.jmedchem.3c01028 |
0.111 |
|
2021 |
Cui H, Huang J, Lei Y, Chen Q, Hu Z, Niu J, Wei R, Yang K, Li H, Lu T, Zhu Y, Huang Y. Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer. European Journal of Medicinal Chemistry. 229: 114082. PMID 34995925 DOI: 10.1016/j.ejmech.2021.114082 |
0.11 |
|
2004 |
Lu T, Stark GR. Cytokine overexpression and constitutive NFkappaB in cancer. Cell Cycle (Georgetown, Tex.). 3: 1114-7. PMID 15492502 DOI: 10.4161/cc.3.9.1130 |
0.11 |
|
2019 |
Wang Y, Hou S, Tong Y, Li H, Hua Y, Fan Y, Chen X, Yang Y, Liu H, Lu T, Chen Y, Zhang Y. Discovery of Potent Apoptosis Signal-Regulating Kinase 1 Inhibitors via Integrated Computational Strategy and Biological Evaluation. Journal of Biomolecular Structure & Dynamics. 1-19. PMID 31612792 DOI: 10.1080/07391102.2019.1680439 |
0.11 |
|
2019 |
Qu Q, Zhang Z, Li Y, Zhou Z, Ye Y, Lu T, Sun L, Qian H. Comparative molecular and metabolic responses of wheat seedlings (Triticum aestivum L.) to the imazethapyr enantiomers S-IM and R-IM. The Science of the Total Environment. 692: 723-731. PMID 31539980 DOI: 10.1016/j.scitotenv.2019.07.333 |
0.11 |
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2021 |
Huang J, Wang X, Dong R, Liu X, Li H, Zhang T, Xu J, Liu C, Zhang Y, Hou S, Tang W, Lu T, Chen Y. Discovery of -(4-(3-isopropyl-2-methyl-2-indazol-5-yl)pyrimidin-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-7-amine as a Novel, Potent, and Oral Cyclin-Dependent Kinase Inhibitor against Haematological Malignancies. Journal of Medicinal Chemistry. PMID 34415148 DOI: 10.1021/acs.jmedchem.1c00271 |
0.11 |
|
2014 |
Zou YM, Hu GY, Zhao XQ, Lu T, Zhu F, Yu SY, Xiong H. Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells. Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 34: 761-7. PMID 25318890 DOI: 10.1007/s11596-014-1349-2 |
0.11 |
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2021 |
Kong B, Zhu Z, Li H, Hong Q, Wang C, Ma Y, Zheng W, Jiang F, Zhang Z, Ran T, Bian Y, Yang N, Lu T, Zhu J, Tang W, et al. Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy. European Journal of Medicinal Chemistry. 227: 113953. PMID 34731760 DOI: 10.1016/j.ejmech.2021.113953 |
0.11 |
|
2022 |
Wang C, Xia J, Lei Y, Lu R, Zhang M, Lv H, Hong Q, Lu T, Chen Y, Li H. Synthesis and biological evaluation of 7H-pyrrolo [2,3-d] pyrimidine derivatives as potential p21-activated kinase 4 (PAK4) inhibitors. Bioorganic & Medicinal Chemistry. 60: 116700. PMID 35272236 DOI: 10.1016/j.bmc.2022.116700 |
0.11 |
|
2019 |
Wang J, Ran T, Chen Y, Lu T. Bayesian Machine Learning to Discover Bruton's Tyrosine Kinase (BTK) Inhibitors. Chemical Biology & Drug Design. PMID 31855311 DOI: 10.1111/cbdd.13656 |
0.109 |
|
2016 |
Lyu C, Hu S, Huang J, Luo M, Lu T, Mei L, Yao S. Contribution of the activated catalase to oxidative stress resistance and γ-aminobutyric acid production in Lactobacillus brevis. International Journal of Food Microbiology. 238: 302-310. PMID 27716473 DOI: 10.1016/j.ijfoodmicro.2016.09.023 |
0.109 |
|
2019 |
Ran T, Li W, Peng B, Xie B, Lu T, Lu S, Liu W. Virtual Screening with Structure-based Pharmacophore Model to Identify Small-molecule Inhibitors of CARM1. Journal of Chemical Information and Modeling. PMID 30607947 DOI: 10.1021/acs.jcim.8b00610 |
0.109 |
|
2020 |
Chen Z, Yang X, Bi G, Liang J, Hu Z, Zhao M, Li M, Lu T, Zheng Y, Sui Q, Yang Y, Zhan C, Jiang W, Wang Q, Tan L. Ligand-receptor interaction atlas within and between tumor cells and T cells in lung adenocarcinoma. International Journal of Biological Sciences. 16: 2205-2219. PMID 32549766 DOI: 10.7150/Ijbs.42080 |
0.109 |
|
2023 |
Duan Y, Zhuang L, Xu Y, Cheng H, Xia J, Lu T, Chen Y. Design, synthesis, and biological evaluation of pyrido[3,2-d]pyrimidine derivatives as novel ATR inhibitors. Bioorganic Chemistry. 136: 106535. PMID 37086581 DOI: 10.1016/j.bioorg.2023.106535 |
0.109 |
|
2012 |
Tai W, Lu T, Yuan H, Wang F, Liu H, Lu S, Leng Y, Zhang W, Jiang Y, Chen Y. Pharmacophore modeling and virtual screening studies to identify new c-Met inhibitors. Journal of Molecular Modeling. 18: 3087-100. PMID 22203475 DOI: 10.1007/s00894-011-1328-5 |
0.109 |
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2020 |
Tong H, Hao Y, Wang K, Xiang L, Lu T. The different benefits and side effects of nivolumab combined with ipilimumab in diverse cancer: A Protocol for Systematic Review. Medicine. 99: e19367. PMID 32176058 DOI: 10.1097/MD.0000000000019367 |
0.065 |
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2017 |
Lu T. Mixed-effects location and scale Tobit joint models for heterogeneous longitudinal data with skewness, detection limits, and measurement errors. Statistical Methods in Medical Research. 962280217704225. PMID 28414259 DOI: 10.1177/0962280217704225 |
0.065 |
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2020 |
Motolani A, Martin M, Sun M, Lu T. Phosphorylation of the Regulators, a Complex Facet of NF-κB Signaling in Cancer. Biomolecules. 11. PMID 33375283 DOI: 10.3390/biom11010015 |
0.065 |
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2021 |
Lu T, Zhang Q, Zhang Z, Hu B, Chen J, Chen J, Qian H. Pollutant toxicology with respect to microalgae and cyanobacteria. Journal of Environmental Sciences (China). 99: 175-186. PMID 33183695 DOI: 10.1016/j.jes.2020.06.033 |
0.065 |
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2007 |
Chen L, Wang X, Lu T, Hou T. Lead optimization and insecticidal activity of analogues of daphneolone isolated from Stellera chamaejasme L. Pest Management Science. 63: 928-34. PMID 17575567 DOI: 10.1002/ps.1399 |
0.065 |
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2019 |
Huang Y, Zhao M, Yin J, Lu T, Yang X, Yuan G, Li M, Liu Y, Zhan C, Wang Q. Pulmonary metastasis in newly diagnosed colon-rectal cancer: a population-based nomogram study. International Journal of Colorectal Disease. PMID 30854572 DOI: 10.1007/s00384-019-03270-w |
0.065 |
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2014 |
Wang M, Sun X, Lu T. Bayesian structured variable selection in linear regression models Computational Statistics. 30: 205-229. DOI: 10.1007/S00180-014-0529-7 |
0.065 |
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2019 |
Fang Z, Haque S, Lin J, Wu R, Zhang J, Wang M, Zhou J, Rafa M, Lu T, Cheng Y. Real-time electrical tuning of an optical spring on a monolithically integrated ultrahigh Q lithium nibote microresonator. Optics Letters. 44: 1214-1217. PMID 30821751 DOI: 10.1364/OL.44.001214 |
0.064 |
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2014 |
Lu Y, Ran T, Lin G, Jin Q, Jin J, Li H, Guo H, Lu T, Wang Y. Novel 1H-pyrazole-3-carboxamide derivatives: synthesis, anticancer evaluation and identification of their DNA-binding interaction. Chemical & Pharmaceutical Bulletin. 62: 238-46. PMID 24365978 DOI: DN/JST.JSTAGE/cpb/c13-00676 |
0.064 |
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2021 |
Zhang Y, Chen H, Liang Y, Lu T, Liu Z, Jin X, Hou L, Xu J, Zhao H, Shi Y, Ahammed GJ. Comparative transcriptomic and metabolomic analyses reveal the protective effects of silicon against low phosphorus stress in tomato plants. Plant Physiology and Biochemistry : Ppb. 166: 78-87. PMID 34090123 DOI: 10.1016/j.plaphy.2021.05.043 |
0.064 |
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2010 |
Yang J, Huang J, Dasgupta M, Sears N, Miyagi M, Wang B, Chance MR, Chen X, Du Y, Wang Y, An L, Wang Q, Lu T, Zhang X, Wang Z, et al. Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proceedings of the National Academy of Sciences of the United States of America. 107: 21499-504. PMID 21098664 DOI: 10.1073/Pnas.1016147107 |
0.064 |
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2012 |
Lu T, Yang Y, Yao B, Liu S, Zhou Y, Zhang C. Template-based structure prediction and classification of transcription factors in Arabidopsis thaliana. Protein Science : a Publication of the Protein Society. 21: 828-38. PMID 22549903 DOI: 10.1002/Pro.2066 |
0.064 |
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2021 |
Gao X, Xu Q, Zhang RH, Lu T, Pan BJ, Liao Q. [Expression and Prognostic Value of Cripto-1 in Pancreatic Cancer]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 43: 173-179. PMID 33966694 DOI: 10.3881/j.issn.1000-503X.12734 |
0.064 |
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2020 |
Xi J, Zhao M, Zheng Y, Liang J, Hu Z, Huang Y, Yang Y, Zhan C, Jiang W, Lu T, Guo W, Wang Q. Development and validation of a nomogram for predicting the overall survival of patients with lung large cell neuroendocrine carcinoma. Translational Cancer Research. 9: 4943-4957. PMID 35117856 DOI: 10.21037/tcr-20-780 |
0.064 |
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2023 |
Bai F, Du Q, Zou Q, Xu L, Dong W, Lv X, Han X, Zhou H, Zhang C, Lu T. The association of blood ctDNA levels to mutations of marker genes in colorectal cancer. Cancer Reports (Hoboken, N.J.). e1782. PMID 36746394 DOI: 10.1002/cnr2.1782 |
0.064 |
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2022 |
Zhang Q, Ye Y, Qu Q, Yu Y, Jin M, Lu T, Qian H. Corrigendum to "Enantioselective metabolomic modulations in Arabidopsis thaliana leaf induced by the herbicide dichlorprop" [Sci. Total Environ. 797 (2021) 149015]. The Science of the Total Environment. 817: 153031. PMID 35038634 DOI: 10.1016/j.scitotenv.2022.153031 |
0.064 |
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2021 |
Mu ZZ, Zhang YQ, Sun D, Lu T, Lin YS. EFFECT OF BRAF AND TERT PROMOTER MUTATIONS ON THYROGLOBULIN RESPONSE IN DISTANT-METASTATIC DIFFERENTIATED THYROID CANCER. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. PMID 34890787 DOI: 10.1016/j.eprac.2021.12.005 |
0.064 |
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2019 |
Zhang Q, Zhu D, Ding J, Zheng F, Zhou S, Lu T, Zhu YG, Qian H. The fungicide azoxystrobin perturbs the gut microbiota community and enriches antibiotic resistance genes in Enchytraeus crypticus. Environment International. 131: 104965. PMID 31284112 DOI: 10.1016/j.envint.2019.104965 |
0.064 |
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2021 |
Wu R, Ruan XL, Ruan DD, Zhang JH, Wang HL, Zeng QZ, Lu T, Gan YM, Luo JW, Wu JB. Differences in gut microbiota structure in patients with stages 4-5 chronic kidney disease. American Journal of Translational Research. 13: 10056-10074. PMID 34650681 |
0.064 |
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2020 |
Li L, Wang M, Chen Y, Hu T, Yang Y, Zhang Y, Bi G, Wang W, Liu E, Han J, Lu T, Su D. Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. Journal of Structural Biology. 107510. PMID 32353513 DOI: 10.1016/j.jsb.2020.107510 |
0.064 |
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2017 |
Lu T, Pan H, Ma J, Li Y, Bokhari SW, Jiang X, Zhu S, Zhang D. Cellulose Nanocrystals/polyacrylamide Composites of High Sensitivity and Cycling Performance to Gauge Humidity. Acs Applied Materials & Interfaces. PMID 28489948 DOI: 10.1021/Acsami.7B04590 |
0.064 |
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2022 |
Yu Y, Zhang Q, Zhang Z, Zhou S, Jin M, Zhu D, Yang X, Qian H, Lu T. Plants select antibiotic resistome in rhizosphere in early stage. The Science of the Total Environment. 858: 159847. PMID 36461576 DOI: 10.1016/j.scitotenv.2022.159847 |
0.064 |
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2019 |
Sun L, Liu Y, Wang Y, Li Y, Liu Z, Lu T, Li W. An efficient synthesis of oxazolines via a cascade reaction between azaoxyallyl cations and 1,2-benzisoxazoles. Organic & Biomolecular Chemistry. PMID 31368471 DOI: 10.1039/c9ob01366k |
0.064 |
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