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Haley V. Hieronymus, Ph.D. - Publications

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Intracellular Compartmentation
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mao N, Gao D, Hu W, Gadal S, Hieronymus H, Wang S, Lee YS, Sullivan P, Zhang Z, Choi D, Rosen N, Sawyers CL, Gopalan A, Chen Y, Carver BS. Oncogenic ERG represses PI3K signaling through down-regulation of IRS2. Cancer Research. PMID 32015092 DOI: 10.1158/0008-5472.Can-19-1394  0.444
2019 Mao N, Gao D, Hu W, Hieronymus H, Wang S, Lee YS, Lee C, Choi D, Gopalan A, Chen Y, Carver BS. Aberrant expression of ERG promotes resistance to combined PI3K and AR pathway inhibition through maintenance of AR target genes. Molecular Cancer Therapeutics. PMID 31296553 DOI: 10.1158/1535-7163.Mct-18-1386  0.437
2018 Hieronymus H, Murali R, Tin A, Yadav K, Abida W, Moller H, Berney D, Scher H, Carver B, Scardino P, Schultz N, Taylor B, Vickers A, Cuzick J, Sawyers CL. Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death. Elife. 7. PMID 30178746 DOI: 10.7554/Elife.37294  0.393
2018 Hieronymus H, Murali R, Tin A, Yadav K, Abida W, Moller H, Berney D, Scher H, Carver B, Scardino P, Schultz N, Taylor B, Vickers A, Cuzick J, Sawyers CL. Author response: Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death Elife. DOI: 10.7554/Elife.37294.027  0.319
2017 Kaittanis C, Andreou C, Hieronymus H, Mao N, Foss CA, Eiber M, Weirich G, Panchal P, Gopalan A, Zurita J, Achilefu S, Chiosis G, Ponomarev V, Schwaiger M, Carver BS, et al. Correction: Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors. The Journal of Experimental Medicine. PMID 29183990 DOI: 10.1084/Jem.2017105211212017C  0.313
2017 Kaittanis C, Andreou C, Hieronymus H, Mao N, Foss CA, Eiber M, Weirich G, Panchal P, Gopalan A, Zurita J, Achilefu S, Chiosis G, Ponomarev V, Schwaiger M, Carver BS, et al. Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors. The Journal of Experimental Medicine. PMID 29141866 DOI: 10.1084/Jem.20171052  0.408
2017 Hieronymus H, Iaquinta PJ, Wongvipat J, Gopalan A, Murali R, Mao N, Carver BS, Sawyers CL. Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis. Nature Communications. 8: 1081. PMID 29057879 DOI: 10.1038/S41467-017-01198-9  0.451
2017 Hieronymus H, Iaquinta PJ, Wongvipat J, Gopalan A, Murali R, Mao N, Carver BS, Sawyers CL. Abstract 1537: 3p13-14FOXP1-SHQ1deletion spanning multiple potential tumor suppressor genes cooperates withPTENloss in cancer Cancer Research. 77: 1537-1537. DOI: 10.1158/1538-7445.Am2017-1537  0.352
2016 Liu X, Grogan TR, Hieronymus H, Hashimoto T, Mottahedeh J, Cheng D, Zhang L, Huang K, Stoyanova T, Park JW, Shkhyan RO, Nowroozizadeh B, Rettig MB, Sawyers CL, Elashoff D, et al. Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome. Cell Reports. 17: 2596-2606. PMID 27926864 DOI: 10.1016/J.Celrep.2016.11.010  0.399
2016 Bose R, Abida W, Iaquinta P, Karthaus W, Armenia J, Wongvipat J, Doran M, Hieronymus H, Philip W, Liang Y, Schultz N, Sawyers CL. Investigation of a frequently mutated transcriptional repressor in prostate cancer, in particular its role in modulating androgen signaling and its effects on TMPRSS2-ERG dependent tumor maintenance. Journal of Clinical Oncology. 34: 274-274. DOI: 10.1200/Jco.2016.34.2_Suppl.274  0.508
2016 Bose R, Abida W, Karthaus W, Armenia J, Iaquinta P, Wongvipat J, Doran M, Hieronymus H, Watson P, Sullivan P, Liang Y, Schultz N, Sawyers C. Abstract LB-018: Loss of function mutations of an ETS repressor expand the ETS positive subset of prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-018  0.479
2015 Wanjala J, Taylor BS, Chapinski C, Hieronymus H, Wongvipat J, Chen Y, Nanjangud GJ, Schultz N, Xie Y, Liu S, Lu W, Yang Q, Sander C, Chen Z, Sawyers CL, et al. Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling. Molecular Cancer Therapeutics. 14: 278-88. PMID 25381262 DOI: 10.1158/1535-7163.Mct-14-0542-T  0.442
2014 Hieronymus H, Schultz N, Gopalan A, Carver BS, Chang MT, Xiao Y, Heguy A, Huberman K, Bernstein M, Assel M, Murali R, Vickers A, Scardino PT, Sander C, Reuter V, et al. Copy number alteration burden predicts prostate cancer relapse. Proceedings of the National Academy of Sciences of the United States of America. 111: 11139-44. PMID 25024180 DOI: 10.1073/Pnas.1411446111  0.42
2014 Blattner M, Lee DJ, O'Reilly C, Park K, MacDonald TY, Khani F, Turner KR, Chiu YL, Wild PJ, Dolgalev I, Heguy A, Sboner A, Ramazangolu S, Hieronymus H, Sawyers C, et al. SPOP mutations in prostate cancer across demographically diverse patient cohorts. Neoplasia (New York, N.Y.). 16: 14-20. PMID 24563616 DOI: 10.1593/Neo.131704  0.385
2014 Blattner M, Lee D, O´Reilly C, Park K, MacDonald TY, Khani F, Turner K, Wild PJ, Hieronymus H, Sawyers CL, Tewari AK, Moch H, Yoon GS, Andrén O, Fall K, et al. Abstract 2244: SPOP mutations in prostate cancer across demographically diverse patient cohorts Cancer Research. 74: 2244-2244. DOI: 10.1158/1538-7445.Am2014-2244  0.346
2013 Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, ... ... Hieronymus H, et al. Androgen receptor signaling regulates DNA repair in prostate cancers. Cancer Discovery. 3: 1245-53. PMID 24027196 DOI: 10.1158/2159-8290.Cd-13-0172  0.425
2012 Hieronymus H, Sawyers CL. Traversing the genomic landscape of prostate cancer from diagnosis to death. Nature Genetics. 44: 613-4. PMID 22641202 DOI: 10.1038/Ng.2301  0.412
2012 Dahlman KB, Parker JS, Shamu T, Hieronymus H, Chapinski C, Carver B, Chang K, Hannon GJ, Sawyers CL. Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening Plos One. 7. PMID 22509301 DOI: 10.1371/Journal.Pone.0034414  0.421
2012 Iaquinta PJ, Wai Chua C, Machado-Pinilla R, Hieronymus H, Wongvipat J, Meier UT, Shen M, Sawyers CL. Abstract PR3: The snoRNP assembly factor SHQ1 is a novel prostate cancer tumor suppressor gene Cancer Research. 72: PR3-PR3. DOI: 10.1158/1538-7445.Prca2012-Pr3  0.473
2012 Taylor BS, Hieronymus H, Schultz N, Sawyers CL. Abstract IA4: Outcome prediction from the pattern of aberrations in prostate cancer genomes Cancer Research. 72. DOI: 10.1158/1538-7445.Prca2012-Ia4  0.428
2011 Yang X, Boehm JS, Yang X, Salehi-Ashtiani K, Hao T, Shen Y, Lubonja R, Thomas SR, Alkan O, Bhimdi T, Green TM, Johannessen CM, Silver SJ, Nguyen C, Murray RR, ... Hieronymus H, et al. A public genome-scale lentiviral expression library of human ORFs. Nature Methods. 8: 659-61. PMID 21706014 DOI: 10.1038/Nmeth.1638  0.33
2011 Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 19: 575-86. PMID 21575859 DOI: 10.1016/J.Ccr.2011.04.008  0.414
2011 Clegg NJ, Couto SS, Wongvipat J, Hieronymus H, Carver BS, Taylor BS, Ellwood-Yen K, Gerald WL, Sander C, Sawyers CL. MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors. Plos One. 6: e17449. PMID 21394210 DOI: 10.1371/Journal.Pone.0017449  0.397
2010 Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell. 18: 11-22. PMID 20579941 DOI: 10.1016/J.Ccr.2010.05.026  0.452
2009 Mitsiades N, Schultz N, Taylor BS, Hieronymus H, Satagopan J, Scardino PT, Reuter VE, Sander C, Sawyers C, Scher HI. Increased expression of androgen receptor (AR) and enzymes involved in androgen synthesis in metastatic prostate cancer: Targets for novel personalized therapies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5002. PMID 27962896 DOI: 10.1200/Jco.2009.27.15_Suppl.5002  0.407
2009 King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nature Genetics. 41: 524-6. PMID 19396167 DOI: 10.1038/Ng.371  0.405
2006 Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR. Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell. 10: 321-30. PMID 17010675 DOI: 10.1016/J.Ccr.2006.09.005  0.414
2004 Hieronymus H, Silver PA. A systems view of mRNP biology. Genes & Development. 18: 2845-60. PMID 15574591 DOI: 10.1101/Gad.1256904  0.527
2004 Hieronymus H, Yu MC, Silver PA. Genome-wide mRNA surveillance is coupled to mRNA export. Genes & Development. 18: 2652-62. PMID 15489286 DOI: 10.1101/Gad.1241204  0.535
2004 Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell. 117: 427-39. PMID 15137937 DOI: 10.1016/S0092-8674(04)00448-9  0.549
2003 Hieronymus H, Silver PA. Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery. Nature Genetics. 33: 155-61. PMID 12524544 DOI: 10.1038/Ng1080  0.54
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