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Adrian W. Serohijos, Ph.D. - Publications

Affiliations: 
2009 Physics & Astronomy University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2009-2015 Chemistry Harvard University, Cambridge, MA, United States 
 2015- Biochemistry Université de Montréal, Montréal, Canada 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Klein EY, Blumenkrantz D, Serohijos A, Shakhnovich E, Choi JM, Rodrigues JV, Smith BD, Lane AP, Feldman A, Pekosz A. Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics. Msphere. 3. PMID 29299534 DOI: 10.1128/mSphereDirect.00554-17  0.771
2017 Desrochers G, Cappadocia L, Lussier-Price M, Ton AT, Ayoubi R, Serohijos A, Omichinski JG, Angers A. Molecular Basis of Interactions Between SH3 Domain-Containing Proteins and the Proline-Rich Region of the Ubiquitin Ligase Itch. The Journal of Biological Chemistry. PMID 28235806 DOI: 10.1074/Jbc.M116.754440  0.376
2016 Bershtein S, Serohijos AW, Shakhnovich EI. Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations. Current Opinion in Structural Biology. 42: 31-40. PMID 27810574 DOI: 10.1016/J.Sbi.2016.10.013  0.666
2016 Chéron N, Serohijos AW, Choi JM, Shakhnovich EI. Evolutionary dynamics of viral escape under antibodies stress: A biophysical model. Protein Science : a Publication of the Protein Society. PMID 26939576 DOI: 10.1002/Pro.2915  0.74
2015 Bershtein S, Serohijos AW, Bhattacharyya S, Manhart M, Choi JM, Mu W, Zhou J, Shakhnovich EI. Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in Bacteria. Plos Genetics. 11: e1005612. PMID 26484862 DOI: 10.1371/Journal.Pgen.1005612  0.751
2015 Zhang H, Cockrell SK, Kolawole AO, Rotem A, Serohijos AW, Chang CB, Tao Y, Mehoke TS, Han Y, Lin JS, Giacobbi NS, Feldman AB, Shakhnovich E, Weitz DA, Wobus CE, et al. Isolation and Analysis of Rare Norovirus Recombinants from Coinfected Mice Using Drop-Based Microfluidics. Journal of Virology. 89: 7722-34. PMID 25972549 DOI: 10.1128/Jvi.01137-15  0.603
2015 Choi JM, Serohijos AW, Murphy S, Lucarelli D, Lofranco LL, Feldman A, Shakhnovich EI. Minimalistic predictor of protein binding energy: contribution of solvation factor to protein binding. Biophysical Journal. 108: 795-8. PMID 25692584 DOI: 10.1016/J.Bpj.2015.01.001  0.748
2014 Dasmeh P, Serohijos AW, Kepp KP, Shakhnovich EI. The influence of selection for protein stability on dN/dS estimations. Genome Biology and Evolution. 6: 2956-67. PMID 25355808 DOI: 10.1093/Gbe/Evu223  0.747
2014 Serohijos AW, Shakhnovich EI. Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics. Current Opinion in Structural Biology. 26: 84-91. PMID 24952216 DOI: 10.1016/J.Sbi.2014.05.005  0.673
2014 Klein EY, Serohijos AW, Choi JM, Shakhnovich EI, Pekosz A. Influenza A H1N1 pandemic strain evolution--divergence and the potential for antigenic drift variants. Plos One. 9: e93632. PMID 24699432 DOI: 10.1371/Journal.Pone.0093632  0.725
2014 Serohijos AW, Shakhnovich EI. Contribution of selection for protein folding stability in shaping the patterns of polymorphisms in coding regions. Molecular Biology and Evolution. 31: 165-76. PMID 24124208 DOI: 10.1093/Molbev/Mst189  0.651
2013 Dasmeh P, Serohijos AW, Kepp KP, Shakhnovich EI. Positively selected sites in cetacean myoglobins contribute to protein stability. Plos Computational Biology. 9: e1002929. PMID 23505347 DOI: 10.1371/Journal.Pcbi.1002929  0.724
2013 Serohijos AW, Lee SY, Shakhnovich EI. Highly abundant proteins favor more stable 3D structures in yeast. Biophysical Journal. 104: L1-3. PMID 23442924 DOI: 10.1016/J.Bpj.2012.11.3838  0.671
2013 Bershtein S, Mu W, Serohijos AW, Zhou J, Shakhnovich EI. Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness. Molecular Cell. 49: 133-44. PMID 23219534 DOI: 10.1016/J.Molcel.2012.11.004  0.699
2012 Serohijos AW, Rimas Z, Shakhnovich EI. Protein biophysics explains why highly abundant proteins evolve slowly. Cell Reports. 2: 249-56. PMID 22938865 DOI: 10.1016/J.Celrep.2012.06.022  0.698
2011 Serohijos AW, Yin S, Ding F, Gauthier J, Gibson DG, Maixner W, Dokholyan NV, Diatchenko L. Structural basis for μ-opioid receptor binding and activation. Structure (London, England : 1993). 19: 1683-90. PMID 22078567 DOI: 10.1016/J.Str.2011.08.003  0.533
2011 Tsygankov D, Serohijos AW, Dokholyan NV, Elston TC. A physical model reveals the mechanochemistry responsible for dynein's processive motion. Biophysical Journal. 101: 144-50. PMID 21723824 DOI: 10.1016/J.Bpj.2011.05.043  0.467
2011 Serohijos AW, Thibodeau PH, Dokholyan NV. Molecular modeling tools and approaches for CFTR and cystic fibrosis. Methods in Molecular Biology (Clifton, N.J.). 741: 347-63. PMID 21594796 DOI: 10.1007/978-1-61779-117-8_23  0.427
2010 Tsygankov D, Serohijos AW, Dokholyan NV, Elston T. A Coupling of Structural and Kinetic Models Reveals the Stepping Mechanics of Dynein Biophysical Journal. 98: 613a. DOI: 10.1016/J.Bpj.2009.12.3345  0.464
2009 Serohijos AW, Tsygankov D, Liu S, Elston TC, Dokholyan NV. Multiscale approaches for studying energy transduction in dynein. Physical Chemistry Chemical Physics : Pccp. 11: 4840-50. PMID 19506759 DOI: 10.1039/B902028D  0.44
2009 Ramachandran S, Serohijos AW, Xu L, Meissner G, Dokholyan NV. A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1). Plos Computational Biology. 5: e1000367. PMID 19390614 DOI: 10.1371/Journal.Pcbi.1000367  0.595
2009 Tsygankov D, Serohijos AW, Dokholyan NV, Elston TC. Kinetic models for the coordinated stepping of cytoplasmic dynein. The Journal of Chemical Physics. 130: 025101. PMID 19154055 DOI: 10.1063/1.3050098  0.445
2009 Ramachandran S, Serohijos AW, Xu L, Meissner G, Dokholyan NV. Ryanodine Receptor Pore Structure and Function Biophysical Journal. 96: 107a. DOI: 10.1016/J.Bpj.2008.12.462  0.599
2009 Riordan JR, Dokholyan N, Serohijos A, Cui L, Hegedus T, Aleksandrov L, He L, Aleksandrov AA. Influence of DF508 on CFTR assembly and function Pediatric Pulmonology. 44: 122-123. DOI: 10.1002/ppul.20948  0.373
2008 Hao J, Serohijos AW, Newton G, Tassone G, Wang Z, Sgroi DC, Dokholyan NV, Basilion JP. Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers. Plos Computational Biology. 4: e1000138. PMID 18670594 DOI: 10.1371/Journal.Pcbi.1000138  0.476
2008 He L, Aleksandrov AA, Serohijos AW, Hegedus T, Aleksandrov LA, Cui L, Dokholyan NV, Riordan JR. Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating. The Journal of Biological Chemistry. 283: 26383-90. PMID 18658148 DOI: 10.1074/jbc.M803894200  0.474
2008 Serohijos AW, Hegedus T, Riordan JR, Dokholyan NV. Diminished self-chaperoning activity of the DeltaF508 mutant of CFTR results in protein misfolding. Plos Computational Biology. 4: e1000008. PMID 18463704 DOI: 10.1371/journal.pcbi.1000008  0.514
2008 Hegedus T, Serohijos AW, Dokholyan NV, He L, Riordan JR. Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR. Journal of Molecular Biology. 378: 1052-63. PMID 18423665 DOI: 10.1016/j.jmb.2008.03.033  0.446
2008 Serohijos AW, Hegedus T, Aleksandrov AA, He L, Cui L, Dokholyan NV, Riordan JR. Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function. Proceedings of the National Academy of Sciences of the United States of America. 105: 3256-61. PMID 18305154 DOI: 10.1073/pnas.0800254105  0.474
2008 Chen Y, Ding F, Nie H, Serohijos AW, Sharma S, Wilcox KC, Yin S, Dokholyan NV. Protein folding: then and now. Archives of Biochemistry and Biophysics. 469: 4-19. PMID 17585870 DOI: 10.1016/J.Abb.2007.05.014  0.757
2006 Serohijos AW, Chen Y, Ding F, Elston TC, Dokholyan NV. A structural model reveals energy transduction in dynein. Proceedings of the National Academy of Sciences of the United States of America. 103: 18540-5. PMID 17121997 DOI: 10.1073/Pnas.0602867103  0.588
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