Nils Brose - Publications

Affiliations: 
Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 
Area:
synapse formation and function

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Year Citation  Score
2024 Koppensteiner P, Bhandari P, Önal C, Borges-Merjane C, Le Monnier E, Roy U, Nakamura Y, Sadakata T, Sanbo M, Hirabayashi M, Rhee J, Brose N, Jonas P, Shigemoto R. GABA receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles. Proceedings of the National Academy of Sciences of the United States of America. 121: e2301449121. PMID 38346189 DOI: 10.1073/pnas.2301449121  0.316
2023 Clavet-Fournier V, Lee C, Wegner W, Brose N, Rhee J, Willig KI. Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. Iscience. 27: 108679. PMID 38213627 DOI: 10.1016/j.isci.2023.108679  0.627
2023 Altas B, Tuffy LP, Patrizi A, Dimova K, Soykan T, Brandenburg C, Romanowski AJ, Whitten JR, Robertson CD, Khim SN, Crutcher GW, Ambrozkiewicz MC, Yagensky O, Krueger-Burg D, Hammer M, ... ... Brose N, et al. Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry. PMID 38154503 DOI: 10.1016/j.biopsych.2023.12.020  0.803
2023 Altas B, Rhee HJ, Ju A, Solís HC, Karaca S, Winchenbach J, Kaplan-Arabaci O, Schwark M, Ambrozkiewicz MC, Lee C, Spieth L, Wieser GL, Chaugule VK, Majoul I, Hassan MA, ... ... Brose N, et al. Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. The Journal of Cell Biology. 223. PMID 38032389 DOI: 10.1083/jcb.201902050  0.78
2023 Singh M, Zhao Y, Gastaldi VD, Wojcik SM, Curto Y, Kawaguchi R, Merino RM, Garcia-Agudo LF, Taschenberger H, Brose N, Geschwind D, Nave KA, Ehrenreich H. Erythropoietin re-wires cognition-associated transcriptional networks. Nature Communications. 14: 4777. PMID 37604818 DOI: 10.1038/s41467-023-40332-8  0.714
2023 Daniel JA, Elizarova S, Shaib AH, Chouaib AA, Magnussen HM, Wang J, Brose N, Rhee J, Tirard M. An intellectual-disability-associated mutation of the transcriptional regulator impairs glutamatergic neurotransmission. Frontiers in Molecular Neuroscience. 16: 1115880. PMID 37533751 DOI: 10.3389/fnmol.2023.1115880  0.673
2023 Rößler N, Jungenitz T, Sigler A, Bird A, Mittag M, Rhee JS, Deller T, Cuntz H, Brose N, Schwarzacher SW, Jedlicka P. Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis. Open Biology. 13: 230063. PMID 37528732 DOI: 10.1098/rsob.230063  0.745
2023 Papantoniou C, Laugks U, Betzin J, Capitanio C, Ferrero JJ, Sánchez-Prieto J, Schoch S, Brose N, Baumeister W, Cooper BH, Imig C, Lučić V. Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming. Science Advances. 9: eadf6222. PMID 37343100 DOI: 10.1126/sciadv.adf6222  0.38
2022 Tan C, de Nola G, Qiao C, Imig C, Born RT, Brose N, Kaeser PS. Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones. Elife. 11. PMID 36398873 DOI: 10.7554/eLife.79077  0.458
2022 Platzer K, Sticht H, Bupp C, Ganapathi M, Pereira EM, Le Guyader G, Bilan F, Henderson LB, Lemke JR, Taschenberger H, Brose N, Abou Jamra R, Wojcik SM. De Novo Missense Variants in SLC32A1 Cause a Developmental and Epileptic Encephalopathy Due to Impaired GABAergic Neurotransmission. Annals of Neurology. PMID 36073542 DOI: 10.1002/ana.26485  0.649
2022 Dhume SH, Connor SA, Mills F, Tari PK, Au-Yeung SHM, Karimi B, Oku S, Roppongi RT, Kawabe H, Bamji SX, Wang YT, Brose N, Jackson MF, Craig AM, Siddiqui TJ. Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits. Elife. 11. PMID 35662394 DOI: 10.7554/eLife.64742  0.819
2022 Elizarova S, Chouaib AA, Shaib A, Hill B, Mann F, Brose N, Kruss S, Daniel JA. A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202842119. PMID 35613050 DOI: 10.1073/pnas.2202842119  0.541
2022 Maxeiner S, Benseler F, Brose N, Krasteva-Christ G. Of Humans and Gerbils- Independent Diversification of Neuroligin-4 Into X- and Y-Specific Genes in Primates and Rodents. Frontiers in Molecular Neuroscience. 15: 838262. PMID 35431802 DOI: 10.3389/fnmol.2022.838262  0.561
2021 Gettings SM, Maxeiner S, Tzika M, Cobain MRD, Ruf I, Benseler F, Brose N, Krasteva-Christ G, Vande Velde G, Schönberger M, Althaus M. Corrigendum to: Two Functional Epithelial Sodium Channel Isoforms Are Present in Rodents despite Pronounced Evolutionary Pseudogenization and Exon Fusion. Molecular Biology and Evolution. PMID 34897515 DOI: 10.1093/molbev/msab328  0.552
2021 Banerjee A, Imig C, Balakrishnan K, Kershberg L, Lipstein N, Uronen RL, Wang J, Cai X, Benseler F, Rhee JS, Cooper BH, Liu C, Wojcik SM, Brose N, Kaeser PS. Molecular and functional architecture of striatal dopamine release sites. Neuron. PMID 34767769 DOI: 10.1016/j.neuron.2021.10.028  0.745
2021 Lipstein N, Chang S, Lin KH, López-Murcia FJ, Neher E, Taschenberger H, Brose N. Munc13-1 is a Ca-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission. Neuron. PMID 34706220 DOI: 10.1016/j.neuron.2021.09.054  0.413
2021 Gettings SM, Maxeiner S, Tzika M, Cobain MRD, Ruf I, Benseler F, Brose N, Krasteva-Christ G, Vande Velde G, Schönberger M, Althaus M. Two functional epithelial sodium channel isoforms are present in rodents despite pronounced evolutionary pseudogenisation and exon fusion. Molecular Biology and Evolution. PMID 34491346 DOI: 10.1093/molbev/msab271  0.576
2021 Wagner S, Lee C, Rojas L, Specht CG, Rhee J, Brose N, Papadopoulos T. The α3 subunit of GABA receptors promotes formation of inhibitory synapses in the absence of collybistin. The Journal of Biological Chemistry. 100709. PMID 33901490 DOI: 10.1016/j.jbc.2021.100709  0.547
2021 Tawfik B, Martins JS, Houy S, Imig C, Pinheiro PS, Wojcik SM, Brose N, Cooper BH, Sørensen JB. Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca-dependent priming. Elife. 10. PMID 33749593 DOI: 10.7554/eLife.64527  0.725
2020 Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C. Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes. The Journal of Biological Chemistry. PMID 33127642 DOI: 10.1074/jbc.RA120.015347  0.311
2020 Imig C, López-Murcia FJ, Maus L, García-Plaza IH, Mortensen LS, Schwark M, Schwarze V, Angibaud J, Nägerl UV, Taschenberger H, Brose N, Cooper BH. Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices. Neuron. PMID 32991831 DOI: 10.1016/j.neuron.2020.09.004  0.384
2020 Nakakubo Y, Abe S, Yoshida T, Takami C, Isa M, Wojcik SM, Brose N, Takamori S, Hori T. Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses. Cell Reports. 32: 108040. PMID 32814044 DOI: 10.1016/J.Celrep.2020.108040  0.8
2020 Ripamonti S, Shomroni O, Rhee JS, Chowdhury K, Jahn O, Hellmann KP, Bonn S, Brose N, Tirard M. SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. Journal of Neurochemistry. PMID 32233089 DOI: 10.1111/jnc.15008  0.533
2020 Maus L, Lee C, Altas B, Sertel SM, Weyand K, Rizzoli SO, Rhee J, Brose N, Imig C, Cooper BH. Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses. Cell Reports. 30: 3632-3643.e8. PMID 32187536 DOI: 10.1016/J.Celrep.2020.02.083  0.847
2020 Nestvogel DB, Merino RM, Leon-Pinzon C, Schottdorf M, Lee C, Imig C, Brose N, Rhee JS. The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex. Cell Reports. 30: 3261-3269.e4. PMID 32160535 DOI: 10.1016/J.Celrep.2020.02.045  0.823
2020 Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, ... ... Brose N, et al. Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron. PMID 32027825 DOI: 10.1016/J.Neuron.2020.01.008  0.718
2020 Maxeiner S, Benseler F, Krasteva-Christ G, Brose N, Südhof TC. Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents. Molecular Biology and Evolution. PMID 32011705 DOI: 10.1093/molbev/msaa014  0.678
2020 Lipstein-Thoms N, Chang S, Lin K, Taschenberger H, Brose N. Ca2+- and Phospholipid-Dependent Mechanisms for the Coupling of Synaptic Vesicle Consumption and Re-Supply Rates Biophysical Journal. 118: 341a. DOI: 10.1016/J.Bpj.2019.11.1897  0.451
2019 Brose N, Brunger A, Cafiso D, Chapman ER, Diao J, Hughson FM, Jackson MB, Jahn R, Lindau M, Ma C, Rizo J, Shin YK, Söllner TH, Tamm L, Yoon TY, et al. Synaptic vesicle fusion: today and beyond. Nature Structural & Molecular Biology. 26: 663-668. PMID 31384060 DOI: 10.1038/S41594-019-0277-Z  0.742
2019 Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, Coba MP, Cornelisse LN, Farrell RJ, Goldschmidt HL, Howrigan DP, Hussain NK, Imig C, de Jong APH, Jung H, Kohansalnodehi M, ... ... Brose N, et al. SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron. PMID 31171447 DOI: 10.1016/J.Neuron.2019.05.002  0.834
2019 Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, Brose N, Brüstle O, Rhee JS. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Reports. 27: 2212-2228.e7. PMID 31091457 DOI: 10.1016/j.celrep.2019.04.059  0.554
2019 López-Murcia FJ, Reim K, Jahn O, Taschenberger H, Brose N. Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release. Cell Reports. 26: 2521-2530.e5. PMID 30840877 DOI: 10.1016/J.Celrep.2019.02.030  0.477
2019 Scholz N, Ehmann N, Sachidanandan D, Imig C, Cooper BH, Jahn O, Reim K, Brose N, Meyer J, Lamberty M, Altrichter S, Bormann A, Hallermann S, Pauli M, Heckmann M, et al. Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix. The Journal of Cell Biology. PMID 30782781 DOI: 10.1083/Jcb.201806155  0.553
2019 Brose N. Dynamic Control of Vesicle Priming in Synaptic Short-Term Plasticity Biophysical Journal. 116: 10a. DOI: 10.1016/j.bpj.2018.11.092  0.467
2018 Babaev O, Cruces-Solis H, Piletti Chatain C, Hammer M, Wenger S, Ali H, Karalis N, de Hoz L, Schlüter OM, Yanagawa Y, Ehrenreich H, Taschenberger H, Brose N, Krueger-Burg D. IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses. Nature Communications. 9: 5400. PMID 30573727 DOI: 10.1038/S41467-018-07762-1  0.8
2018 Neher E, Brose N. Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity. Neuron. 100: 1283-1291. PMID 30571941 DOI: 10.1016/j.neuron.2018.11.024  0.531
2018 Bhouri M, Morishita W, Temkin P, Goswami D, Kawabe H, Brose N, Südhof TC, Craig AM, Siddiqui TJ, Malenka R. Deletion of in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 29784826 DOI: 10.1073/Pnas.1803280115  0.867
2018 Daniel JA, Cooper BH, Palvimo JJ, Zhang FP, Brose N, Tirard M. Response: Commentary: Analysis of SUMO1-conjugation at synapses. Frontiers in Cellular Neuroscience. 12: 117. PMID 29766991 DOI: 10.3389/fncel.2018.00117  0.684
2018 Zhang B, Gokce O, Hale WD, Brose N, Südhof TC. Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. The Journal of Experimental Medicine. PMID 29724786 DOI: 10.1084/Jem.20172162  0.813
2018 Peters F, Salihoglu H, Rodrigues E, Herzog E, Blume T, Filser S, Dorostkar M, Shimshek DR, Brose N, Neumann U, Herms J. BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology. Acta Neuropathologica. PMID 29327084 DOI: 10.1007/S00401-017-1804-9  0.731
2018 Davis GW, Brose N. Decision letter: Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts Elife. DOI: 10.7554/Elife.40744.021  0.451
2018 Rizo J, Brose N, Richmond JE. Decision letter: Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming in C. elegans Elife. DOI: 10.7554/Elife.40585.012  0.456
2017 Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, ... ... Brose N, et al. Building Bridges through Science. Neuron. 96: 730-735. PMID 29144972 DOI: 10.1016/J.Neuron.2017.09.028  0.723
2017 Unichenko P, Yang JW, Kirischuk S, Kolbaev S, Kilb W, Hammer M, Krueger-Burg D, Brose N, Luhmann HJ. Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex. Cerebral Cortex (New York, N.Y. : 1991). 1-14. PMID 29106499 DOI: 10.1093/cercor/bhx165  0.799
2017 Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT. Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. Neuron. 95: 591-607.e10. PMID 28772123 DOI: 10.1016/J.Neuron.2017.07.004  0.824
2017 Daniel JA, Cooper BH, Palvimo JJ, Zhang FP, Brose N, Tirard M. Analysis of SUMO1-conjugation at Synapses. Elife. 6. PMID 28598330 DOI: 10.7554/eLife.26338  0.755
2017 Krueger-Burg D, Papadopoulos T, Brose N. Organizers of inhibitory synapses come of age. Current Opinion in Neurobiology. 45: 66-77. PMID 28460365 DOI: 10.1016/j.conb.2017.04.003  0.83
2017 Chehab T, Santos NC, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Nazmi AR, Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V. A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Molecular Biology of the Cell. 28: 1688-1700. PMID 28450451 DOI: 10.1091/Mbc.E17-02-0128  0.786
2017 Sigler A, Oh WC, Imig C, Altas B, Kawabe H, Cooper BH, Kwon HB, Rhee JS, Brose N. Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release. Neuron. 94: 304-311.e4. PMID 28426965 DOI: 10.1016/J.Neuron.2017.03.029  0.849
2017 Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Cooper BH, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, ... ... Brose N, et al. Correction: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology. PMID 28289090 DOI: 10.1083/jcb.20160608603092017c  0.838
2017 Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, Rosenmund C, ... ... Brose N, et al. ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology. PMID 28264913 DOI: 10.1083/Jcb.201606086  0.855
2017 Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, Toselli M, Brose N, Parenti M, Rhee J. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. Elife. 6. PMID 28231043 DOI: 10.7554/Elife.22466  0.842
2017 Lipstein N, Verhoeven-Duif NM, Michelassi FE, Calloway N, van Hasselt PM, Pienkowska K, van Haaften G, van Haelst MM, van Empelen R, Cuppen I, van Teeseling HC, Evelein AM, Vorstman JA, Thoms S, Jahn O, ... ... Brose N, et al. Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of Clinical Investigation. PMID 28192369 DOI: 10.1172/Jci90259  0.698
2017 Daniel JA, Cooper BH, Palvimo JJ, Zhang F, Brose N, Tirard M. Author response: Analysis of SUMO1-conjugation at synapses Elife. DOI: 10.7554/Elife.26338.021  0.431
2017 Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, Toselli M, Brose N, Parenti M, Rhee J. Author response: Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons Elife. DOI: 10.7554/Elife.22466.027  0.805
2016 Schreiner D, Savas JN, Herzog E, Brose N, de Wit J. Synapse biology in the 'circuit-age'-paths toward molecular connectomics. Current Opinion in Neurobiology. 42: 102-110. PMID 28033531 DOI: 10.1016/J.Conb.2016.12.004  0.776
2016 Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. Endosomal Phosphatidylinositol-3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses. The Journal of Biological Chemistry. PMID 27941024 DOI: 10.1074/jbc.M116.771592  0.697
2016 Strenzke N, Chakrabarti R, Al-Moyed H, Müller A, Hoch G, Pangrsic T, Yamanbaeva G, Lenz C, Pan KT, Auge E, Geiss-Friedlander R, Urlaub H, Brose N, Wichmann C, Reisinger E. Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants. The Embo Journal. PMID 27729456 DOI: 10.15252/Embj.201694564  0.391
2016 Tirard M, Brose N. Systematic Localization and Identification of SUMOylation Substrates in Knock-In Mice Expressing Affinity-Tagged SUMO1. Methods in Molecular Biology (Clifton, N.J.). 1475: 291-301. PMID 27631813 DOI: 10.1007/978-1-4939-6358-4_20  0.307
2016 Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology. PMID 27454932 DOI: 10.1038/Nchembio.2141  0.552
2016 Babai N, Sendelbeck A, Regus-Leidig H, Fuchs M, Mertins J, Reim K, Brose N, Feigenspan A, Brandstätter JH. Functional Roles of Complexin3 and Complexin4 at Mouse Photoreceptor Ribbon Synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6651-67. PMID 27335398 DOI: 10.1523/JNEUROSCI.4335-15.2016  0.557
2016 Mortensen LS, Park SJ, Ke JB, Cooper BH, Zhang L, Imig C, Löwel S, Reim K, Brose N, Demb JB, Rhee JS, Singer JH. Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses. Cell Reports. PMID 27239031 DOI: 10.1016/J.Celrep.2016.05.012  0.606
2016 Okamoto Y, Lipstein N, Hua Y, Lin KH, Brose N, Sakaba T, Midorikawa M. Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice. Elife. 5. PMID 27154627 DOI: 10.7554/eLife.14643  0.462
2016 Okamoto Y, Lipstein N, Hua Y, Lin K, Brose N, Sakaba T, Midorikawa M. Author response: Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice Elife. DOI: 10.7554/Elife.14643.018  0.331
2015 Wüstefeld L, Winkler D, Janc OA, Hassouna I, Ronnenberg A, Ostmeier K, Müller M, Brose N, Ehrenreich H, Wojcik SM. Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition. Journal of Neurochemistry. PMID 26613978 DOI: 10.1111/jnc.13445  0.709
2015 Man KM, Imig C, Walter AM, Pinheiro PS, Stevens DR, Rettig J, Sørensen JB, Cooper BH, Brose N, Wojcik SM. Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife. 4. PMID 26575293 DOI: 10.7554/Elife.10635  0.838
2015 Ludolphs M, Schneeberger D, Soykan T, Schäfer J, Papadopoulos T, Brose N, Schindelin H, Steinem C. Specificity of collybistin-phosphoinositide interactions: Impact of the individual protein domains. The Journal of Biological Chemistry. PMID 26546675 DOI: 10.1074/Jbc.M115.673400  0.779
2015 Hammer M, Krueger-Burg D, Tuffy LP, Cooper BH, Taschenberger H, Goswami SP, Ehrenreich H, Jonas P, Varoqueaux F, Rhee JS, Brose N. Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism. Cell Reports. 13: 516-23. PMID 26456829 DOI: 10.1016/J.Celrep.2015.09.011  0.848
2015 Lipina TV, Prasad T, Yokomaku D, Luo L, Connor SA, Kawabe H, Tian Wang Y, Brose N, Roder JC, Marie Craig A. Cognitive Deficits in Calsyntenin-2 Deficient Mice Associated with Reduced Gabaergic Transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26171716 DOI: 10.1038/Npp.2015.206  0.688
2015 Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D. Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala. Neuropharmacology. PMID 26142252 DOI: 10.1016/j.neuropharm.2015.06.016  0.814
2015 Schotten S, Meijer M, Walter AM, Huson V, Mamer L, Kalogreades L, Veer MT, Ruiter M, Brose N, Rosenmund C, Sørensen JB, Verhage M, Cornelisse LN. Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate. Elife. 4. PMID 26041332 DOI: 10.7554/eLife.09036  0.727
2015 Chang S, Reim K, Pedersen M, Neher E, Brose N, Taschenberger H. Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8272-90. PMID 26019341 DOI: 10.1523/Jneurosci.4841-14.2015  0.578
2015 Schotten S, Meijer M, Walter AM, Huson V, Mamer L, Kalogreades L, ter Veer M, Ruiter M, Brose N, Rosenmund C, Sørensen JB, Verhage M, Cornelisse LN. Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate. Elife. 4: e05531. PMID 25871846 DOI: 10.7554/Elife.05531  0.756
2015 Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW. Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Structure & Function. 220: 47-58. PMID 25713840 DOI: 10.1007/S00429-013-0636-1  0.72
2015 Papadopoulos T, Schemm R, Grubmüller H, Brose N. Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. The Journal of Biological Chemistry. 290: 8256-70. PMID 25678704 DOI: 10.1074/Jbc.M114.633024  0.46
2015 Netrakanti PR, Cooper BH, Dere E, Poggi G, Winkler D, Brose N, Ehrenreich H. Fast cerebellar reflex circuitry requires synaptic vesicle priming by munc13-3. Cerebellum (London, England). 14: 264-83. PMID 25617111 DOI: 10.1007/s12311-015-0645-0  0.497
2015 Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C. Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells. Journal of Cell Science. 128: 638-44. PMID 25609709 DOI: 10.1242/Jcs.162099  0.822
2015 Man KNM, Imig C, Walter AM, Pinheiro PS, Stevens DR, Rettig J, Sørensen JB, Cooper BH, Brose N, Wojcik SM. Author response: Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis Elife. DOI: 10.7554/Elife.10635.019  0.329
2015 Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D. Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala Neuropharmacology. DOI: 10.1016/j.neuropharm.2015.06.016  0.793
2014 Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J. Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain. Cell Reports. 9: 902-9. PMID 25437547 DOI: 10.1016/J.Celrep.2014.09.050  0.81
2014 Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron. 84: 416-31. PMID 25374362 DOI: 10.1016/J.Neuron.2014.10.009  0.813
2014 Ishiyama S, Schmidt H, Cooper BH, Brose N, Eilers J. Munc13-3 superprimes synaptic vesicles at granule cell-to-basket cell synapses in the mouse cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14687-96. PMID 25355221 DOI: 10.1523/Jneurosci.2060-14.2014  0.546
2014 Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, ... ... Brose N, et al. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth. Proceedings of the National Academy of Sciences of the United States of America. 111: 13205-10. PMID 25157163 DOI: 10.1073/Pnas.1400737111  0.739
2014 Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N. A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. The Embo Journal. 33: 2113-33. PMID 25082542 DOI: 10.15252/Embj.201488143  0.837
2014 Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, Moghadam PK, Bost A, Schirra C, Rettig J, Reim K, Brose N, Mohrmann R, Bruns D. Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics. The Journal of Cell Biology. 204: 1123-40. PMID 24687280 DOI: 10.1083/Jcb.201311085  0.414
2014 Brose N. All roads lead to neuroscience: the 2013 Nobel Prize in Physiology or Medicine. Neuron. 81: 723-7. PMID 24559668 DOI: 10.1016/j.neuron.2014.02.008  0.326
2014 Kleijer KT, Schmeisser MJ, Krueger DD, Boeckers TM, Scheiffele P, Bourgeron T, Brose N, Burbach JP. Neurobiology of autism gene products: towards pathogenesis and drug targets. Psychopharmacology. 231: 1037-62. PMID 24419271 DOI: 10.1007/S00213-013-3403-3  0.374
2014 Biesemann C, Grønborg M, Luquet E, Wichert SP, Bernard V, Bungers SR, Cooper B, Varoqueaux F, Li L, Byrne JA, Urlaub H, Jahn O, Brose N, Herzog E. Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. The Embo Journal. 33: 157-70. PMID 24413018 DOI: 10.1002/Embj.201386120  0.811
2014 Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. Correction to The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones[Neuron, (2014), 84, 416-431] Neuron. 84: 882. DOI: 10.1016/j.neuron.2014.11.003  0.68
2013 Mayer S, Kumar R, Jaiswal M, Soykan T, Ahmadian MR, Brose N, Betz H, Rhee JS, Papadopoulos T. Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 110: 20795-800. PMID 24297911 DOI: 10.1073/Pnas.1309078110  0.827
2013 Pettem KL, Yokomaku D, Luo L, Linhoff MW, Prasad T, Connor SA, Siddiqui TJ, Kawabe H, Chen F, Zhang L, Rudenko G, Wang YT, Brose N, Craig AM. The specific α-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse development. Neuron. 80: 113-28. PMID 24094106 DOI: 10.1016/J.Neuron.2013.07.016  0.826
2013 Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW. Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Structure & Function. PMID 24077800 DOI: 10.1007/s00429-013-0636-1  0.689
2013 Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N, Craig AM. An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells. Neuron. 79: 680-95. PMID 23911104 DOI: 10.1016/J.Neuron.2013.06.029  0.843
2013 Lipstein N, Sakaba T, Cooper BH, Lin KH, Strenzke N, Ashery U, Rhee JS, Taschenberger H, Neher E, Brose N. Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling. Neuron. 79: 82-96. PMID 23770256 DOI: 10.1016/J.Neuron.2013.05.011  0.665
2013 Wojcik SM, Tantra M, Stepniak B, Man KN, Müller-Ribbe K, Begemann M, Ju A, Papiol S, Ronnenberg A, Gurvich A, Shin Y, Augustin I, Brose N, Ehrenreich H. Genetic markers of a Munc13 protein family member, BAIAP3, are gender specifically associated with anxiety and benzodiazepine abuse in mice and humans. Molecular Medicine (Cambridge, Mass.). 19: 135-48. PMID 23698091 DOI: 10.2119/Molmed.2013.00033  0.776
2013 Krueger DD, Brose N. Evidence for a common endocannabinoid-related pathomechanism in autism spectrum disorders. Neuron. 78: 408-10. PMID 23664608 DOI: 10.1016/j.neuron.2013.04.030  0.345
2013 Dolev I, Fogel H, Milshtein H, Berdichevsky Y, Lipstein N, Brose N, Gazit N, Slutsky I. Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change. Nature Neuroscience. 16: 587-95. PMID 23563578 DOI: 10.1038/Nn.3376  0.437
2013 Brose N. Why we need more synaptogenic cell-adhesion proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 3717-8. PMID 23426626 DOI: 10.1073/pnas.1300505110  0.524
2013 Nair R, Lauks J, Jung S, Cooke NE, de Wit H, Brose N, Kilimann MW, Verhage M, Rhee J. Neurobeachin regulates neurotransmitter receptor trafficking to synapses. The Journal of Cell Biology. 200: 61-80. PMID 23277425 DOI: 10.1085/Jgp1411Oia2  0.749
2013 El-Kordi A, Winkler D, Hammerschmidt K, Kästner A, Krueger D, Ronnenberg A, Ritter C, Jatho J, Radyushkin K, Bourgeron T, Fischer J, Brose N, Ehrenreich H. Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism. Behavioural Brain Research. 251: 41-9. PMID 23183221 DOI: 10.1016/J.Bbr.2012.11.016  0.326
2013 Wojcik S, Tantra M, Stepniak B, Man K, Müller-Ribbe K, Begemann M, Ju A, Papiol S, Ronnenberg A, Gurvich A, Shin Y, Augustin I, Brose N, Ehrenreich H. Baiap3 as a genetic marker associated with anxiety and benzodiazepine abuse in mouse and man Experimental and Clinical Endocrinology & Diabetes. 121. DOI: 10.1055/s-0033-1359431  0.753
2012 Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, Young C, Rodriguez EP, Saetzler K, Frotscher M. Structural plasticity of spines at giant mossy fiber synapses. Frontiers in Neural Circuits. 6: 103. PMID 23264762 DOI: 10.3389/fncir.2012.00103  0.47
2012 Tirard M, Hsiao HH, Nikolov M, Urlaub H, Melchior F, Brose N. In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21122-7. PMID 23213215 DOI: 10.1073/pnas.1215366110  0.318
2012 Lipstein N, Schaks S, Dimova K, Kalkhof S, Ihling C, Kölbel K, Ashery U, Rhee J, Brose N, Sinz A, Jahn O. Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity. Molecular and Cellular Biology. 32: 4628-41. PMID 22966208 DOI: 10.1128/Mcb.00933-12  0.667
2012 Riccomagno MM, Hurtado A, Wang H, Macopson JG, Griner EM, Betz A, Brose N, Kazanietz MG, Kolodkin AL. The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus. Cell. 149: 1594-606. PMID 22726444 DOI: 10.1016/J.Cell.2012.05.018  0.31
2012 Burgalossi A, Jung S, Man KN, Nair R, Jockusch WJ, Wojcik SM, Brose N, Rhee JS. Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system. Nature Protocols. 7: 1351-65. PMID 22722370 DOI: 10.1038/Nprot.2012.074  0.811
2012 Cooper B, Hemmerlein M, Ammermüller J, Imig C, Reim K, Lipstein N, Kalla S, Kawabe H, Brose N, Brandstätter JH, Varoqueaux F. Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8040-52. PMID 22674279 DOI: 10.1523/Jneurosci.4240-11.2012  0.776
2012 Poulopoulos A, Soykan T, Tuffy LP, Hammer M, Varoqueaux F, Brose N. Homodimerization and isoform-specific heterodimerization of neuroligins. The Biochemical Journal. 446: 321-30. PMID 22671294 DOI: 10.1042/Bj20120808  0.822
2012 Krueger DD, Tuffy LP, Papadopoulos T, Brose N. The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses. Current Opinion in Neurobiology. 22: 412-22. PMID 22424845 DOI: 10.1016/J.Conb.2012.02.012  0.847
2012 Ivanovic A, Horresh I, Golan N, Spiegel I, Sabanay H, Frechter S, Ohno S, Terada N, Möbius W, Rosenbluth J, Brose N, Peles E. The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves. The Journal of Cell Biology. 196: 337-44. PMID 22291039 DOI: 10.1083/Jcb.201111127  0.647
2012 Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, Young C, Rodriguez EP, Saetzler K, Frotscher M. Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing. The Journal of Comparative Neurology. 520: 2340-51. PMID 22237743 DOI: 10.1002/cne.23040  0.464
2012 Halt AR, Dallapiazza RF, Zhou Y, Stein IS, Qian H, Juntti S, Wojcik S, Brose N, Silva AJ, Hell JW. CaMKII binding to GluN2B is critical during memory consolidation. The Embo Journal. 31: 1203-16. PMID 22234183 DOI: 10.1038/Emboj.2011.482  0.782
2012 Burgalossi A, Jung S, Meyer G, Jockusch W, Jahn O, Taschenberger H, O'Connor V, Nishiki Ti, Takahashi M, Brose N, Rhee JS. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming Neuron. 73: 620. DOI: 10.1016/j.neuron.2012.01.015  0.834
2011 Herzog E, Nadrigny F, Silm K, Biesemann C, Helling I, Bersot T, Steffens H, Schwartzmann R, Nägerl UV, El Mestikawy S, Rhee J, Kirchhoff F, Brose N. In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15544-59. PMID 22031900 DOI: 10.1523/Jneurosci.2073-11.2011  0.856
2011 Kawabe H, Brose N. The role of ubiquitylation in nerve cell development. Nature Reviews. Neuroscience. 12: 251-68. PMID 21505515 DOI: 10.1038/Nrn3009  0.657
2011 Reisinger E, Bresee C, Neef J, Nair R, Reuter K, Bulankina A, Nouvian R, Koch M, Bückers J, Kastrup L, Roux I, Petit C, Hell SW, Brose N, Rhee JS, et al. Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4886-95. PMID 21451027 DOI: 10.1523/Jneurosci.5122-10.2011  0.615
2011 Nouvian R, Neef J, Bulankina AV, Reisinger E, PangrÅ¡ič T, Frank T, Sikorra S, Brose N, Binz T, Moser T. Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins. Nature Neuroscience. 14: 411-3. PMID 21378973 DOI: 10.1038/Nn.2774  0.452
2011 Kimura T, Kawabe H, Jiang C, Zhang W, Xiang YY, Lu C, Salter MW, Brose N, Lu WY, Rotin D. Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 3216-21. PMID 21300902 DOI: 10.1073/Pnas.1010334108  0.584
2011 Hoon M, Soykan T, Falkenburger B, Hammer M, Patrizi A, Schmidt KF, Sassoè-Pognetto M, Löwel S, Moser T, Taschenberger H, Brose N, Varoqueaux F. Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina. Proceedings of the National Academy of Sciences of the United States of America. 108: 3053-8. PMID 21282647 DOI: 10.1073/Pnas.1006946108  0.819
2011 Jedlicka P, Hoon M, Papadopoulos T, Vlachos A, Winkels R, Poulopoulos A, Betz H, Deller T, Brose N, Varoqueaux F, Schwarzacher SW. Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo. Cerebral Cortex (New York, N.Y. : 1991). 21: 357-67. PMID 20530218 DOI: 10.1093/Cercor/Bhq100  0.808
2011 Rohan JG, Lin SM, Cho JH, Cai H, Reim K, Brose N, Ko C, Chow RH. Complexin Facilitates Coupling of Secretory Vesicles and Voltage-Gated Calcium Channels Biophysical Journal. 100: 31a. DOI: 10.1016/j.bpj.2010.12.374  0.395
2010 Burgalossi A, Jung S, Meyer G, Jockusch WJ, Jahn O, Taschenberger H, O'Connor VM, Nishiki T, Takahashi M, Brose N, Rhee JS. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron. 68: 473-87. PMID 21040848 DOI: 10.1016/J.Neuron.2010.09.019  0.859
2010 Liu Y, Schirra C, Edelmann L, Matti U, Rhee J, Hof D, Bruns D, Brose N, Rieger H, Stevens DR, Rettig J. Two distinct secretory vesicle-priming steps in adrenal chromaffin cells. The Journal of Cell Biology. 190: 1067-77. PMID 20855507 DOI: 10.1083/Jcb.201001164  0.584
2010 Pangrsic T, Lasarow L, Reuter K, Takago H, Schwander M, Riedel D, Frank T, Tarantino LM, Bailey JS, Strenzke N, Brose N, Müller U, Reisinger E, Moser T. Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells. Nature Neuroscience. 13: 869-76. PMID 20562868 DOI: 10.1038/Nn.2578  0.558
2010 Kawabe H, Brose N. The ubiquitin E3 ligase Nedd4-1 controls neurite development. Cell Cycle (Georgetown, Tex.). 9: 2477-8. PMID 20543564 DOI: 10.4161/Cc.9.13.12236  0.598
2010 Brose N, O'Connor V, Skehel P. Synaptopathy: dysfunction of synaptic function? Biochemical Society Transactions. 38: 443-4. PMID 20298199 DOI: 10.1042/Bst0380443  0.408
2010 Kawabe H, Neeb A, Dimova K, Young SM, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, ... ... Brose N, et al. Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 65: 358-72. PMID 20159449 DOI: 10.1515/Nf-2010-0205  0.781
2010 Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund C, Südhof TC. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nature Structural & Molecular Biology. 17: 280-8. PMID 20154707 DOI: 10.1038/Nsmb.1758  0.826
2010 Groffen AJ, Martens S, Díez Arazola R, Cornelisse LN, Lozovaya N, de Jong AP, Goriounova NA, Habets RL, Takai Y, Borst JG, Brose N, McMahon HT, Verhage M. Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science (New York, N.Y.). 327: 1614-8. PMID 20150444 DOI: 10.1126/Science.1183765  0.706
2010 Fouladkou F, Lu C, Jiang C, Zhou L, She Y, Walls JR, Kawabe H, Brose N, Henkelman RM, Huang A, Bruneau BG, Rotin D. The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1. The Journal of Biological Chemistry. 285: 6770-80. PMID 20026598 DOI: 10.1074/Jbc.M109.082347  0.615
2010 Rodríguez-Castañeda F, Coudevylle N, Becker S, Brose N, Carlomagno T, Griesinger C. 1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex. Biomolecular Nmr Assignments. 4: 45-8. PMID 20013162 DOI: 10.1007/S12104-009-9204-2  0.365
2010 Rodríguez-Castañeda F, Maestre-Martínez M, Coudevylle N, Dimova K, Junge H, Lipstein N, Lee D, Becker S, Brose N, Jahn O, Carlomagno T, Griesinger C. Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. The Embo Journal. 29: 680-91. PMID 20010694 DOI: 10.1038/Emboj.2009.373  0.772
2010 Breustedt J, Gundlfinger A, Varoqueaux F, Reim K, Brose N, Schmitz D. Munc13-2 differentially affects hippocampal synaptic transmission and plasticity. Cerebral Cortex (New York, N.Y. : 1991). 20: 1109-20. PMID 19700493 DOI: 10.1093/cercor/bhp170  0.568
2010 Kawabe H, Neeb A, Dimova K, Young S, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova O, Zhang D, Umikawa M, Kariya K, Goebbels S, Nave K, Rosenmund C, Jahn O, ... ... Brose N, et al. O1-3-2-3Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.025  0.73
2009 Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, ... ... Brose N, et al. Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. 138: 1222-35. PMID 19766573 DOI: 10.1016/J.Cell.2009.06.050  0.735
2009 Poulopoulos A, Aramuni G, Meyer G, Soykan T, Hoon M, Papadopoulos T, Zhang M, Paarmann I, Fuchs C, Harvey K, Jedlicka P, Schwarzacher SW, Betz H, Harvey RJ, Brose N, et al. Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. Neuron. 63: 628-42. PMID 19755106 DOI: 10.1016/J.Neuron.2009.08.023  0.862
2009 Brose N, Neher E. Flowers for synaptic endocytosis. Cell. 138: 836-7. PMID 19737513 DOI: 10.1016/j.cell.2009.08.023  0.531
2009 Wittenmayer N, Körber C, Liu H, Kremer T, Varoqueaux F, Chapman ER, Brose N, Kuner T, Dresbach T. Postsynaptic Neuroligin1 regulates presynaptic maturation. Proceedings of the National Academy of Sciences of the United States of America. 106: 13564-9. PMID 19628693 DOI: 10.1073/Pnas.0905819106  0.717
2009 Siksou L, Varoqueaux F, Pascual O, Triller A, Brose N, Marty S. A common molecular basis for membrane docking and functional priming of synaptic vesicles. The European Journal of Neuroscience. 30: 49-56. PMID 19558619 DOI: 10.1111/j.1460-9568.2009.06811.x  0.425
2009 Strenzke N, Chanda S, Kopp-Scheinpflug C, Khimich D, Reim K, Bulankina AV, Neef A, Wolf F, Brose N, Xu-Friedman MA, Moser T. Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7991-8004. PMID 19553439 DOI: 10.1523/Jneurosci.0632-09.2009  0.625
2009 Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez-Castaneda F, Liepold T, Griesinger C, Brose N, Sinz A, Jahn O. Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry. 48: 5908-21. PMID 19492809 DOI: 10.1021/Bi900300R  0.412
2009 Reim K, Regus-Leidig H, Ammermüller J, El-Kordi A, Radyushkin K, Ehrenreich H, Brandstätter JH, Brose N. Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4. Journal of Cell Science. 122: 1352-61. PMID 19386896 DOI: 10.1242/jcs.045401  0.513
2009 Brose N. Synaptogenic proteins and synaptic organizers: "many hands make light work". Neuron. 61: 650-2. PMID 19285459 DOI: 10.1016/j.neuron.2009.02.014  0.51
2009 Wozny C, Breustedt J, Wolk F, Varoqueaux F, Boretius S, Zivkovic AR, Neeb A, Frahm J, Schmitz D, Brose N, Ivanovic A. The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression. Journal of Cell Science. 122: 735-44. PMID 19225127 DOI: 10.1242/Jcs.037382  0.755
2009 Schenck S, Wojcik SM, Brose N, Takamori S. A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles. Nature Neuroscience. 12: 156-62. PMID 19169251 DOI: 10.1038/nn.2248  0.76
2009 Blundell J, Tabuchi K, Bolliger MF, Blaiss CA, Brose N, Liu X, Südhof TC, Powell CM. Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2. Genes, Brain, and Behavior. 8: 114-26. PMID 19016888 DOI: 10.1111/J.1601-183X.2008.00455.X  0.654
2009 Brunk I, Blex C, Speidel D, Brose N, Ahnert-Hilger G. Ca2+-dependent activator proteins of secretion promote vesicular monoamine uptake. The Journal of Biological Chemistry. 284: 1050-6. PMID 19008227 DOI: 10.1074/jbc.M805328200  0.431
2008 Cai H, Reim K, Varoqueaux F, Tapechum S, Hill K, Sørensen JB, Brose N, Chow RH. Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming. Proceedings of the National Academy of Sciences of the United States of America. 105: 19538-43. PMID 19033464 DOI: 10.1073/pnas.0810232105  0.457
2008 Adamcio B, Sargin D, Stradomska A, Medrihan L, Gertler C, Theis F, Zhang M, Müller M, Hassouna I, Hannke K, Sperling S, Radyushkin K, El-Kordi A, Schulze L, Ronnenberg A, ... ... Brose N, et al. Erythropoietin enhances hippocampal long-term potentiation and memory. Bmc Biology. 6: 37. PMID 18782446 DOI: 10.1186/1741-7007-6-37  0.639
2008 Patrizi A, Scelfo B, Viltono L, Briatore F, Fukaya M, Watanabe M, Strata P, Varoqueaux F, Brose N, Fritschy JM, Sassoè-Pognetto M. Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 105: 13151-6. PMID 18723687 DOI: 10.1073/Pnas.0802390105  0.505
2008 Lou X, Korogod N, Brose N, Schneggenburger R. Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8257-67. PMID 18701688 DOI: 10.1523/Jneurosci.0550-08.2008  0.442
2008 Fouladkou F, Landry T, Kawabe H, Neeb A, Lu C, Brose N, Stambolic V, Rotin D. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proceedings of the National Academy of Sciences of the United States of America. 105: 8585-90. PMID 18562292 DOI: 10.1073/Pnas.0803233105  0.628
2008 Xue M, Stradomska A, Chen H, Brose N, Zhang W, Rosenmund C, Reim K. Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 105: 7875-80. PMID 18505837 DOI: 10.1073/pnas.0803012105  0.735
2008 Liu Y, Schirra C, Stevens DR, Matti U, Speidel D, Hof D, Bruns D, Brose N, Rettig J. CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5594-601. PMID 18495893 DOI: 10.1523/JNEUROSCI.5672-07.2008  0.402
2008 Brose N. For better or for worse: complexins regulate SNARE function and vesicle fusion. Traffic (Copenhagen, Denmark). 9: 1403-13. PMID 18445121 DOI: 10.1111/j.1600-0854.2008.00758.x  0.488
2008 Brose N. Altered complexin expression in psychiatric and neurological disorders: cause or consequence? Molecules and Cells. 25: 7-19. PMID 18319609  0.364
2008 Zikich D, Mezer A, Varoqueaux F, Sheinin A, Junge HJ, Nachliel E, Melamed R, Brose N, Gutman M, Ashery U. Vesicle priming and recruitment by ubMunc13-2 are differentially regulated by calcium and calmodulin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1949-60. PMID 18287511 DOI: 10.1523/Jneurosci.5096-07.2008  0.754
2008 Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, Varoqueaux F, Ramanantsoa N, Gallego J, Ronnenberg A, Winter D, Frahm J, Fischer J, Bourgeron T, Ehrenreich H, Brose N. Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proceedings of the National Academy of Sciences of the United States of America. 105: 1710-5. PMID 18227507 DOI: 10.1073/Pnas.0711555105  0.428
2008 Speidel D, Salehi A, Obermueller S, Lundquist I, Brose N, Renström E, Rorsman P. CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells. Cell Metabolism. 7: 57-67. PMID 18177725 DOI: 10.1016/J.Cmet.2007.11.009  0.302
2007 Jockusch WJ, Speidel D, Sigler A, Sørensen JB, Varoqueaux F, Rhee JS, Brose N. CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell. 131: 796-808. PMID 18022372 DOI: 10.1016/J.Cell.2007.11.002  0.705
2007 Xue M, Reim K, Chen X, Chao HT, Deng H, Rizo J, Brose N, Rosenmund C. Distinct domains of complexin I differentially regulate neurotransmitter release. Nature Structural & Molecular Biology. 14: 949-58. PMID 17828276 DOI: 10.1038/Nsmb1292  0.678
2007 Wojcik SM, Brose N. Regulation of membrane fusion in synaptic excitation-secretion coupling: speed and accuracy matter. Neuron. 55: 11-24. PMID 17610814 DOI: 10.1016/j.neuron.2007.06.013  0.777
2007 Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC. Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron. 54: 919-31. PMID 17582332 DOI: 10.1016/J.Neuron.2007.05.029  0.848
2007 Basu J, Betz A, Brose N, Rosenmund C. Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1200-10. PMID 17267576 DOI: 10.1523/JNEUROSCI.4908-06.2007  0.686
2007 Tordera RM, Totterdell S, Wojcik SM, Brose N, Elizalde N, Lasheras B, Del Rio J. Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1). The European Journal of Neuroscience. 25: 281-90. PMID 17241289 DOI: 10.1111/j.1460-9568.2006.05259.x  0.76
2007 Kawabe H, Rhee J, Katsurabayashi S, Neeb A, Umikawa M, Kariya K, Rosenmund C, Brose N. Regulation of dendritic development by E3 ubiquitin ligase Nedd4 Neuroscience Research. 58: S39. DOI: 10.1016/J.Neures.2007.06.228  0.754
2006 Kalla S, Stern M, Basu J, Varoqueaux F, Reim K, Rosenmund C, Ziv NE, Brose N. Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13054-66. PMID 17167095 DOI: 10.1523/JNEUROSCI.4330-06.2006  0.656
2006 Dimova K, Kawabe H, Betz A, Brose N, Jahn O. Characterization of the Munc13-calmodulin interaction by photoaffinity labeling. Biochimica Et Biophysica Acta. 1763: 1256-65. PMID 17049382 DOI: 10.1016/J.Bbamcr.2006.09.017  0.708
2006 Varoqueaux F, Aramuni G, Rawson RL, Mohrmann R, Missler M, Gottmann K, Zhang W, Südhof TC, Brose N. Neuroligins determine synapse maturation and function. Neuron. 51: 741-54. PMID 16982420 DOI: 10.1016/J.Neuron.2006.09.003  0.792
2006 Herzog E, Takamori S, Jahn R, Brose N, Wojcik SM. Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus. Journal of Neurochemistry. 99: 1011-8. PMID 16942593 DOI: 10.1111/J.1471-4159.2006.04144.X  0.851
2006 Andrews-Zwilling YS, Kawabe H, Reim K, Varoqueaux F, Brose N. Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. The Journal of Biological Chemistry. 281: 19720-31. PMID 16704978 DOI: 10.1074/Jbc.M601421200  0.752
2006 Wojcik SM, Katsurabayashi S, Guillemin I, Friauf E, Rosenmund C, Brose N, Rhee JS. A shared vesicular carrier allows synaptic corelease of GABA and glycine. Neuron. 50: 575-87. PMID 16701208 DOI: 10.1016/j.neuron.2006.04.016  0.827
2006 Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T. Munc13-1 is required for the sustained release of insulin from pancreatic beta cells. Cell Metabolism. 3: 463-8. PMID 16697276 DOI: 10.1016/J.Cmet.2006.04.012  0.393
2006 Vinatier J, Herzog E, Plamont MA, Wojcik SM, Schmidt A, Brose N, Daviet L, El Mestikawy S, Giros B. Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis. Journal of Neurochemistry. 97: 1111-25. PMID 16606361 DOI: 10.1111/J.1471-4159.2006.03821.X  0.824
2005 Stevens DR, Wu ZX, Matti U, Junge HJ, Schirra C, Becherer U, Wojcik SM, Brose N, Rettig J. Identification of the minimal protein domain required for priming activity of Munc13-1. Current Biology : Cb. 15: 2243-8. PMID 16271475 DOI: 10.1016/J.Cub.2005.10.055  0.828
2005 Gibson HE, Reim K, Brose N, Morton AJ, Jones S. A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse. The European Journal of Neuroscience. 22: 1701-12. PMID 16197510 DOI: 10.1111/j.1460-9568.2005.04349.x  0.358
2005 Varoqueaux F, Sons MS, Plomp JJ, Brose N. Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse. Molecular and Cellular Biology. 25: 5973-84. PMID 15988013 DOI: 10.1128/MCB.25.14.5973-5984.2005  0.587
2005 Reim K, Wegmeyer H, Brandstätter JH, Xue M, Rosenmund C, Dresbach T, Hofmann K, Brose N. Structurally and functionally unique complexins at retinal ribbon synapses. The Journal of Cell Biology. 169: 669-80. PMID 15911881 DOI: 10.1083/Jcb.200502115  0.698
2005 Speidel D, Bruederle CE, Enk C, Voets T, Varoqueaux F, Reim K, Becherer U, Fornai F, Ruggieri S, Holighaus Y, Weihe E, Bruns D, Brose N, Rettig J. CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron. 46: 75-88. PMID 15820695 DOI: 10.1016/j.neuron.2005.02.019  0.426
2005 Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, Aitken A, Wiltfang J, Aguzzi A, Bahn E, Baxter HC, Brose N, Otto M. Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Molecular and Cellular Biology. 25: 1339-46. PMID 15684385 DOI: 10.1128/Mcb.25.4.1339-1346.2005  0.315
2005 Neeft M, Wieffer M, de Jong AS, Negroiu G, Metz CH, van Loon A, Griffith J, Krijgsveld J, Wulffraat N, Koch H, Heck AJ, Brose N, Kleijmeer M, van der Sluijs P. Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. Molecular Biology of the Cell. 16: 731-41. PMID 15548590 DOI: 10.1091/Mbc.E04-10-0923  0.357
2004 Varoqueaux F, Jamain S, Brose N. Neuroligin 2 is exclusively localized to inhibitory synapses. European Journal of Cell Biology. 83: 449-56. PMID 15540461 DOI: 10.1078/0171-9335-00410  0.578
2004 Dresbach T, Neeb A, Meyer G, Gundelfinger ED, Brose N. Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding. Molecular and Cellular Neurosciences. 27: 227-35. PMID 15519238 DOI: 10.1016/J.Mcn.2004.06.013  0.678
2004 Meyer G, Varoqueaux F, Neeb A, Oschlies M, Brose N. The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Neuropharmacology. 47: 724-33. PMID 15458844 DOI: 10.1016/J.Neuropharm.2004.06.023  0.619
2004 Junge HJ, Rhee JS, Jahn O, Varoqueaux F, Spiess J, Waxham MN, Rosenmund C, Brose N. Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity. Cell. 118: 389-401. PMID 15294163 DOI: 10.1016/J.Cell.2004.06.029  0.849
2004 Brose N, Betz A, Wegmeyer H. Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals. Current Opinion in Neurobiology. 14: 328-40. PMID 15194113 DOI: 10.1016/j.conb.2004.05.006  0.311
2004 Rossner S, Fuchsbrunner K, Lange-Dohna C, Hartlage-Rübsamen M, Bigl V, Betz A, Reim K, Brose N. Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing. The Journal of Biological Chemistry. 279: 27841-4. PMID 15123597 DOI: 10.1074/jbc.C400122200  0.403
2004 Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N, Rosenmund C. An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proceedings of the National Academy of Sciences of the United States of America. 101: 7158-63. PMID 15103023 DOI: 10.1073/Pnas.0401764101  0.829
2004 Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, Neher E, Sørensen JB. Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron. 41: 417-29. PMID 14766180 DOI: 10.1016/S0896-6273(04)00038-8  0.383
2003 Meyer G, Brose N. Neuroscience. SPARring with spines. Science (New York, N.Y.). 302: 1341-4. PMID 14631024 DOI: 10.1126/Science.1092039  0.651
2003 Rosenmund C, Rettig J, Brose N. Molecular mechanisms of active zone function. Current Opinion in Neurobiology. 13: 509-19. PMID 14630212 DOI: 10.1016/j.conb.2003.09.011  0.626
2003 Speidel D, Varoqueaux F, Enk C, Nojiri M, Grishanin RN, Martin TF, Hofmann K, Brose N, Reim K. A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function. The Journal of Biological Chemistry. 278: 52802-9. PMID 14530279 DOI: 10.1074/Jbc.M304727200  0.466
2003 Tobaben S, Varoqueaux F, Brose N, Stahl B, Meyer G. A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein. The Journal of Biological Chemistry. 278: 38376-83. PMID 12878599 DOI: 10.1074/Jbc.M301558200  0.539
2003 Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY. Regulation of insulin exocytosis by Munc13-1. The Journal of Biological Chemistry. 278: 27556-63. PMID 12871971 DOI: 10.1074/Jbc.M303203200  0.343
2003 Sørensen JB, Nagy G, Varoqueaux F, Nehring RB, Brose N, Wilson MC, Neher E. Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell. 114: 75-86. PMID 12859899 DOI: 10.1016/S0092-8674(03)00477-X  0.403
2002 Brose N, Neher E. Specificity emerges in the dissection of diacylglycerol- and protein kinase C-mediated signalling pathways. Proceedings of the National Academy of Sciences of the United States of America. 99: 16522-3. PMID 12486246 DOI: 10.1073/pnas.022708199  0.462
2002 Brose N, Rosenmund C. Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. Journal of Cell Science. 115: 4399-411. PMID 12414987 DOI: 10.1242/jcs.00122  0.565
2002 Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences of the United States of America. 99: 9037-42. PMID 12070347 DOI: 10.1073/Pnas.122623799  0.799
2002 Antonin W, Wagner M, Riedel D, Brose N, Jahn R. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Molecular and Cellular Biology. 22: 1545-54. PMID 11839820 DOI: 10.1128/MCB.22.5.1545-1554.2002  0.512
2002 Rosenmund C, Sigler A, Augustin I, Reim K, Brose N, Rhee JS. Differential control of vesicle priming and short-term plasticity by Munc13 isoforms. Neuron. 33: 411-24. PMID 11832228 DOI: 10.1016/S0896-6273(02)00568-8  0.784
2002 Rhee JS, Betz A, Pyott S, Reim K, Varoqueaux F, Augustin I, Hesse D, Südhof TC, Takahashi M, Rosenmund C, Brose N. Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs. Cell. 108: 121-33. PMID 11792326 DOI: 10.1016/S0092-8674(01)00635-3  0.745
2001 Betz A, Thakur P, Junge HJ, Ashery U, Rhee JS, Scheuss V, Rosenmund C, Rettig J, Brose N. Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming. Neuron. 30: 183-96. PMID 11343654 DOI: 10.1016/S0896-6273(01)00272-0  0.866
2001 Schmitz F, Augustin I, Brose N. The synaptic vesicle priming protein Munc13-1 is absent from tonically active ribbon synapses of the rat retina. Brain Research. 895: 258-63. PMID 11259787 DOI: 10.1016/S0006-8993(01)02078-9  0.557
2001 Fernández-Chacón R, Königstorfer A, Gerber SH, García J, Matos MF, Stevens CF, Brose N, Rizo J, Rosenmund C, Südhof TC. Synaptotagmin I functions as a calcium regulator of release probability. Nature. 410: 41-9. PMID 11242035 DOI: 10.1038/35065004  0.649
2001 Reim K, Mansour M, Varoqueaux F, McMahon HT, Südhof TC, Brose N, Rosenmund C. Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell. 104: 71-81. PMID 11163241 DOI: 10.1016/S0092-8674(01)00192-1  0.658
2001 Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW, Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 10-7. PMID 11150314 DOI: 10.1523/Jneurosci.21-01-00010.2001  0.676
2000 Ashery U, Varoqueaux F, Voets T, Betz A, Thakur P, Koch H, Neher E, Brose N, Rettig J. Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells. The Embo Journal. 19: 3586-96. PMID 10899113 DOI: 10.1093/emboj/19.14.3586  0.441
2000 Koch H, Hofmann K, Brose N. Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform. The Biochemical Journal. 349: 247-53. PMID 10861235 DOI: 10.1042/0264-6021:3490247  0.445
2000 Brose N, Rosenmund C, Rettig J. Regulation of transmitter release by Unc-13 and its homologues. Current Opinion in Neurobiology. 10: 303-11. PMID 10851170 DOI: 10.1016/S0959-4388(00)00105-7  0.692
1999 Brose N, Rosenmund C. SV2: SVeeping up excess Ca2+ or tranSVorming presynaptic Ca2+ sensors? Neuron. 24: 766-8. PMID 10624939 DOI: 10.1016/S0896-6273(00)81023-5  0.557
1999 Brose N. Synaptic cell adhesion proteins and synaptogenesis in the mammalian central nervous system. Die Naturwissenschaften. 86: 516-24. PMID 10551945 DOI: 10.1007/s001140050666  0.401
1999 Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H. Evidence of presynaptic location and function of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8866-75. PMID 10516306 DOI: 10.1523/Jneurosci.19-20-08866.1999  0.66
1999 Neeb A, Koch H, Schürmann A, Brose N. Direct interaction between the ARF-specific guanine nucleotide exchange factor msec7-1 and presynaptic Munc13-1. European Journal of Cell Biology. 78: 533-8. PMID 10494859 DOI: 10.1016/S0171-9335(99)80018-1  0.474
1999 Ashery U, Betz A, Xu T, Brose N, Rettig J. An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system. European Journal of Cell Biology. 78: 525-32. PMID 10494858 DOI: 10.1016/S0171-9335(99)80017-X  0.341
1999 Augustin I, Rosenmund C, Südhof TC, Brose N. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature. 400: 457-61. PMID 10440375 DOI: 10.1038/22768  0.747
1999 Song JY, Ichtchenko K, Südhof TC, Brose N. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proceedings of the National Academy of Sciences of the United States of America. 96: 1100-5. PMID 9927700 DOI: 10.1073/pnas.96.3.1100  0.557
1999 Ashery U, Koch H, Scheuss V, Brose N, Rettig J. A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 1094-9. PMID 9927699 DOI: 10.1073/pnas.96.3.1094  0.515
1999 Augustin I, Betz A, Herrmann C, Jo T, Brose N. Differential expression of two novel Munc13 proteins in rat brain. The Biochemical Journal. 337: 363-71. PMID 9895278 DOI: 10.1042/0264-6021:3370363  0.44
1998 Betz A, Ashery U, Rickmann M, Augustin I, Neher E, Südhof TC, Rettig J, Brose N. Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron. 21: 123-36. PMID 9697857 DOI: 10.1016/S0896-6273(00)80520-6  0.594
1997 Betz A, Okamoto M, Benseler F, Brose N. Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. The Journal of Biological Chemistry. 272: 2520-6. PMID 8999968 DOI: 10.1074/jbc.272.4.2520  0.48
1996 Betz A, Telemenakis I, Hofmann K, Brose N. Mammalian Unc-13 homologues as possible regulators of neurotransmitter release. Biochemical Society Transactions. 24: 661-6. PMID 8878822 DOI: 10.1042/Bst0240661  0.342
1996 Chapman ER, Blasi J, An S, Brose N, Johnston PA, Südhof TC, Jahn R. Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. Biochemical and Biophysical Research Communications. 225: 326-32. PMID 8769138 DOI: 10.1006/Bbrc.1996.1174  0.648
1995 Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Nature. 375: 594-9. PMID 7791877 DOI: 10.1038/375594a0  0.385
1995 Brose N, Hofmann K, Hata Y, Südhof TC. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. The Journal of Biological Chemistry. 270: 25273-80. PMID 7559667 DOI: 10.1074/jbc.270.42.25273  0.377
1994 Siegel SJ, Brose N, Janssen WG, Gasic GP, Jahn R, Heinemann SF, Morrison JH. Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 91: 564-8. PMID 8290563 DOI: 10.1073/Pnas.91.2.564  0.664
1994 Huntley GW, Vickers JC, Janssen W, Brose N, Heinemann SF, Morrison JH. Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3603-19. PMID 8207475 DOI: 10.1523/Jneurosci.14-06-03603.1994  0.578
1994 Brose N, Huntley GW, Stern-Bach Y, Sharma G, Morrison JH, Heinemann SF. Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex. The Journal of Biological Chemistry. 269: 16780-4. PMID 8207001  0.747
1994 Trevisan L, Fitzgerald LW, Brose N, Gasic GP, Heinemann SF, Duman RS, Nestler EJ. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. Journal of Neurochemistry. 62: 1635-8. PMID 8133290 DOI: 10.1046/j.1471-4159.1994.62041635.x  0.494
1994 Spiro JE, Brose N, Heinemann SF, Heiligenberg W. Immunolocalization of NMDA receptors in the central nervous system of weakly electric fish: functional implications for the modulation of a neuronal oscillator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6289-99. PMID 7931581 DOI: 10.1523/Jneurosci.14-10-06289.1994  0.54
1994 Puchalski RB, Louis JC, Brose N, Traynelis SF, Egebjerg J, Kukekov V, Wenthold RJ, Rogers SW, Lin F, Moran T. Selective RNA editing and subunit assembly of native glutamate receptors. Neuron. 13: 131-47. PMID 7519023 DOI: 10.1016/0896-6273(94)90464-2  0.526
1993 Brose N. Membrane fusion takes excitatory turn: syntaxin, vesicle docking protein, or glutamate receptor? Cell. 75: 1043-4. PMID 8261506 DOI: 10.1016/0092-8674(93)90313-F  0.406
1993 Brose N, Gasic GP, Vetter DE, Sullivan JM, Heinemann SF. Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1. The Journal of Biological Chemistry. 268: 22663-71. PMID 8226775  0.757
1993 Sucher NJ, Brose N, Deitcher DL, Awobuluyi M, Gasic GP, Bading H, Cepko CL, Greenberg ME, Jahn R, Heinemann SF. Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells. The Journal of Biological Chemistry. 268: 22299-304. PMID 8226739  0.629
1992 Brose N, Petrenko AG, Südhof TC, Jahn R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science (New York, N.Y.). 256: 1021-5. PMID 1589771 DOI: 10.1126/Science.1589771  0.563
1992 Jahn R, Brose N, von Mollard GF. Molecular steps involved in exocytosis and recycling of synaptic vesicles Neurochemistry International. 21: Q18. DOI: 10.1016/0197-0186(92)91854-P  0.648
1991 Perin MS, Brose N, Jahn R, Südhof TC. Domain structure of synaptotagmin (p65) The Journal of Biological Chemistry. 266: 623-9. PMID 1985919  0.504
1990 Brose N, Thomas A, Weber MG, Jahn R. A chloride- and calcium-dependent glutamate-binding protein from rat brain. Identification as a ubiquitous constituent of the inner mitochondrial membrane. The Journal of Biological Chemistry. 265: 10604-10. PMID 2162355 DOI: 10.1016/0197-0186(90)90249-S  0.426
1989 Brose N, O'Neill RD, Boutelle MG, Fillenz M. The effects of anxiolytic and anxiogenic benzodiazepine receptor ligands on motor activity and levels of ascorbic acid in the nucleus accumbens and striatum of the rat. Neuropharmacology. 28: 509-14. PMID 2566950 DOI: 10.1016/0028-3908(89)90087-7  0.463
1989 Brose N, Halpain S, Suchanek C, Jahn R. Characterization and partial purification of a chloride- and calcium-dependent glutamate-binding protein from rat brain. The Journal of Biological Chemistry. 264: 9619-25. PMID 2566612  0.429
1988 Brose N, O'Neill RD, Boutelle MG, Fillenz M. Dopamine in the basal ganglia and benzodiazepine-induced sedation. Neuropharmacology. 27: 589-95. PMID 3419542 DOI: 10.1016/0028-3908(88)90179-7  0.449
1987 Brose N, O'Neill RD, Boutelle MG, Anderson SM, Fillenz M. Effects of an anxiogenic benzodiazepine receptor ligand on motor activity and dopamine release in nucleus accumbens and striatum in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 2917-26. PMID 3040928 DOI: 10.1523/Jneurosci.07-09-02917.1987  0.531
1987 Brose N, O'Neill R, Boutelle M, Anderson S, Fillenz M. Effects of an anxiogenic benzodiazepine receptor ligand on motor activity and dopamine release in nucleus accumbens and striatum in the rat The Journal of Neuroscience. 7: 2917-2926. DOI: 10.1523/JNEUROSCI.07-09-02917.1987  0.472
Low-probability matches (unlikely to be authored by this person)
2005 Glynn D, Drew CJ, Reim K, Brose N, Morton AJ. Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits. Human Molecular Genetics. 14: 2369-85. PMID 16000319 DOI: 10.1093/hmg/ddi239  0.298
2007 Wegmeyer H, Egea J, Rabe N, Gezelius H, Filosa A, Enjin A, Varoqueaux F, Deininger K, Schnütgen F, Brose N, Klein R, Kullander K, Betz A. EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron. 55: 756-67. PMID 17785182 DOI: 10.1016/J.Neuron.2007.07.038  0.296
2009 Radyushkin K, Hammerschmidt K, Boretius S, Varoqueaux F, El-Kordi A, Ronnenberg A, Winter D, Frahm J, Fischer J, Brose N, Ehrenreich H. Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit. Genes, Brain, and Behavior. 8: 416-25. PMID 19243448 DOI: 10.1111/J.1601-183X.2009.00487.X  0.295
2020 Chitirala P, Chang HF, Martzloff P, Harenberg C, Ravichandran K, Abdulreda MH, Berggren PO, Krause E, Schirra C, Leinders-Zufall T, Benseler F, Brose N, Rettig J. Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse. Elife. 9. PMID 32696761 DOI: 10.7554/eLife.58065  0.288
2010 Radyushkin K, El-Kordi A, Boretius S, Castaneda S, Ronnenberg A, Reim K, Bickeböller H, Frahm J, Brose N, Ehrenreich H. Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia. Genes, Brain, and Behavior. 9: 592-602. PMID 20412316 DOI: 10.1111/J.1601-183X.2010.00590.X  0.285
2001 Brose N, Song J. The Rendezvous of Axon with Dendrite German Research. 23: 36-37. DOI: 10.1002/1522-2322(200105)23:2/3<36::AID-GERM36>3.0.CO;2-L  0.283
2007 Glynn D, Reim K, Brose N, Morton AJ. Depletion of Complexin II does not affect disease progression in a mouse model of Huntington's disease (HD); support for role for complexin II in behavioural pathology in a mouse model of HD. Brain Research Bulletin. 72: 108-20. PMID 17352934 DOI: 10.1016/j.brainresbull.2006.10.017  0.282
2014 Ju A, Hammerschmidt K, Tantra M, Krueger D, Brose N, Ehrenreich H. Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism. Behavioural Brain Research. 270: 159-64. PMID 24855039 DOI: 10.1016/J.Bbr.2014.05.019  0.28
2010 Begemann M, Grube S, Papiol S, Malzahn D, Krampe H, Ribbe K, Friedrichs H, Radyushkin KA, El-Kordi A, Benseler F, Hannke K, Sperling S, Schwerdtfeger D, Thanhäuser I, Gerchen MF, ... ... Brose N, et al. Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. Archives of General Psychiatry. 67: 879-88. PMID 20819981 DOI: 10.1001/Archgenpsychiatry.2010.107  0.272
1999 Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H. Evidence of Presynaptic Location and Function of the Prion Protein The Journal of Neuroscience. 19: 8866-8875. DOI: 10.1523/JNEUROSCI.19-20-08866.1999  0.258
2004 Causevic M, Betz A, Brose N, Burgoyne RD, Gandy S. P4-180 The roles of phorbol ester targets MUNC13 and MUNC18 in vesicular trafficking and processing of the Alzheimer's disease amyloid precursor protein Neurobiology of Aging. 25: S526. DOI: 10.1016/S0197-4580(04)81738-X  0.258
2006 Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY. Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55: 1421-9. PMID 16644700 DOI: 10.2337/Db05-1263  0.257
2023 Chen H, Fang Q, Benseler F, Brose N, Moser T. Probing the role of the CF domain of otoferlin. Frontiers in Molecular Neuroscience. 16: 1299509. PMID 38152587 DOI: 10.3389/fnmol.2023.1299509  0.253
2011 Grube S, Gerchen MF, Adamcio B, Pardo LA, Martin S, Malzahn D, Papiol S, Begemann M, Ribbe K, Friedrichs H, Radyushkin KA, Müller M, Benseler F, Riggert J, Falkai P, ... ... Brose N, et al. A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia. Embo Molecular Medicine. 3: 309-19. PMID 21433290 DOI: 10.1002/Emmm.201100135  0.251
2017 Lahut S, Gispert S, Ömür Ö, Depboylu C, Seidel K, Domínguez-Bautista JA, Brehm N, Tireli H, Hackmann K, Pirkevi C, Leube B, Ries V, Reim K, Brose N, den Dunnen WF, et al. Blood RNA biomarkers in prodromal PARK4 and REM sleep behavior disorder show role of complexin-1 loss for risk of Parkinson's disease. Disease Models & Mechanisms. PMID 28108469 DOI: 10.1242/Dmm.028035  0.249
1999 Duncan RR, Betz A, Shipston MJ, Brose N, Chow RH. Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo. The Journal of Biological Chemistry. 274: 27347-50. PMID 10488064 DOI: 10.1074/Jbc.274.39.27347  0.232
2023 Suk TR, Nguyen TT, Fisk ZA, Mitkovski M, Geertsma HM, Parmasad JA, Heer MM, Callaghan SM, Benseler F, Brose N, Tirard M, Rousseaux MWC. Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain. Iscience. 26: 106350. PMID 37009224 DOI: 10.1016/j.isci.2023.106350  0.221
2021 Hilton BJ, Husch A, Schaffran B, Lin TC, Burnside ER, Dupraz S, Schelski M, Kim J, Müller JA, Schoch S, Imig C, Brose N, Bradke F. An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury. Neuron. PMID 34706221 DOI: 10.1016/j.neuron.2021.10.007  0.218
2010 Ribbe K, Friedrichs H, Begemann M, Grube S, Papiol S, Kästner A, Gerchen MF, Ackermann V, Tarami A, Treitz A, Flögel M, Adler L, Aldenhoff JB, Becker-Emner M, Becker T, ... ... Brose N, et al. The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients. Bmc Psychiatry. 10: 91. PMID 21067598 DOI: 10.1186/1471-244X-10-91  0.216
2013 Ferro-Novick S, Brose N. Nobel 2013 Physiology or medicine: Traffic control system within cells. Nature. 504: 98. PMID 24305158 DOI: 10.1038/504098A  0.215
2020 Chitirala P, Chang H, Martzloff P, Harenberg C, Ravichandran K, Abdulreda MH, Berggren P, Krause E, Schirra C, Leinders-Zufall T, Benseler F, Brose N, Rettig J. Author response: Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse Elife. DOI: 10.7554/Elife.58065.Sa2  0.212
2010 Klaus S, Begemann M, Papiol S, Malzahn D, Friedrichs H, Ribbe K, El-Kordi A, Radyushkin K, Benseler F, Reim K, Riggert J, Falkai P, Bickeböller H, Nave K, Brose N, et al. Complexin2 Gene Polymorphisms Modify Cognitive Performance In Schizophrenia Schizophrenia Research. 117: 337-338. DOI: 10.1016/J.Schres.2010.02.583  0.193
2017 Brose N. Can Autistic Behavioural Disfunctions Be Explained by Biological Causes and Hence Be Treated Medically Latest Thinking. DOI: 10.21036/Ltpub10270  0.186
2018 Hong W, Brose N, Cohen JY, Caroni P, Hsiao EY, Kaeser PS. Setting the stage for the next generation of neuroscience Neuron. 99: 11-12. PMID 30001505 DOI: 10.1016/J.Neuron.2018.06.043  0.182
1994 Böckers TM, Zimmer M, Müller A, Bergmann M, Brose N, Kreutz MR. Expression of the NMDA R1 receptor in selected human brain regions. Neuroreport. 5: 965-9. PMID 8061305 DOI: 10.1097/00001756-199404000-00028  0.159
2023 Jentoft IMA, Bäuerlein FJB, Welp LM, Cooper BH, Petrovic A, So C, Penir SM, Politi AZ, Horokhovskyi Y, Takala I, Eckel H, Moltrecht R, Lénárt P, Cavazza T, Liepe J, ... Brose N, et al. Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell. PMID 37922900 DOI: 10.1016/j.cell.2023.10.003  0.156
1997 Telemenakis I, Benseler F, Stenius K, Südhof TC, Brose N. Rat homologues of yeast sec7p. European Journal of Cell Biology. 74: 143-9. PMID 9352219  0.153
2023 Chen H, Monga M, Fang Q, Slitin L, Neef J, Chepurwar SS, Mingroni Netto RC, Lezirovitz K, Tabith A, Benseler F, Brose N, Kusch K, Wichmann C, Strenzke N, Vona B, et al. Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing. Protein & Cell. PMID 38066594 DOI: 10.1093/procel/pwad058  0.141
2021 Segelcke D, Fischer HK, Hütte M, Dennerlein S, Benseler F, Brose N, Pogatzki-Zahn EM, Schmidt M. Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice. Cell Reports. 37: 110152. PMID 34936870 DOI: 10.1016/j.celrep.2021.110152  0.071
2007 Brose N. Neurogenetics: Autism - When nerve cells are shy | Neurogenetik: Autismus - Wenn nervenzellen kontaktscheu sind Biospektrum. 13: 614-616.  0.056
2008 Brose N, Keil JP. Resting energy expenditure of long-term intensive patients | Energieumsatz bei langzeit-intensivpatienten Aktuelle Ernahrungsmedizin. 33: 184-188. DOI: 10.1055/s-2008-1067412  0.029
2013 Brose N. Specification of meteorological data requirements for a wind power infeed model used in power system simulator 12th International Conference On Environment and Electrical Engineering, Eeeic 2013. 140-144. DOI: 10.1109/EEEIC.2013.6549605  0.028
2008 Brose N. Entscheidung unter unsicherheit - Familiengründung und -erweiterung im erwerbsverlauf Kolner Zeitschrift Fur Soziologie Und Sozialpsychologie. 60: 30-52. DOI: 10.1007/s11577-008-0002-0  0.01
1950 THOMPSON JE, BROSE NA, SMITHWICK RH. Patterns of electrical skin resistance following sympathectomy. Archives of Surgery (Chicago, Ill. : 1920). 60: 431-55. PMID 15403711  0.01
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