Ryjul W. Stokes - Publications

Affiliations: 
2018- Chemistry and Biochemistry University of California, San Diego, La Jolla, CA 
Area:
Medicinal Chemistry

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kohlbrand AJ, Stokes RW, Sankaran B, Cohen SM. Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry. PMID 38190441 DOI: 10.1021/acs.biochem.3c00536  0.374
2023 Morrison CN, Prosser KE, Stokes RW, Cordes A, Metzler-Nolte N, Cohen SM. Erratum: Further correction: Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery. Chemical Science. 14: 10360-10362. PMID 37772109 DOI: 10.1039/d3sc90164e  0.758
2023 Seo H, Kohlbrand AJ, Stokes RW, Chung J, Cohen SM. Correction: Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs. Chemical Communications (Cambridge, England). 59: 3614. PMID 36912505 DOI: 10.1039/d3cc90087h  0.373
2023 Seo H, Kohlbrand AJ, Stokes RW, Chung J, Cohen SM. Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs. Chemical Communications (Cambridge, England). PMID 36735025 DOI: 10.1039/d2cc06596g  0.459
2022 Stokes RW, Kohlbrand AJ, Seo H, Sankaran B, Karges J, Cohen SM. Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors. Acs Medicinal Chemistry Letters. 14: 75-82. PMID 36655124 DOI: 10.1021/acsmedchemlett.2c00434  0.427
2022 Morrison CN, Prosser KE, Stokes RW, Cordes A, Metzler-Nolte N, Cohen SM. Correction: Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery. Chemical Science. 13: 9450-9452. PMID 36093021 DOI: 10.1039/d2sc90145e  0.758
2022 Karges J, Stokes RW, Cohen SM. Computational Prediction of the Binding Pose of Metal-Binding Pharmacophores. Acs Medicinal Chemistry Letters. 13: 428-435. PMID 35300086 DOI: 10.1021/acsmedchemlett.1c00584  0.414
2021 Karges J, Stokes RW, Cohen SM. Metal Complexes for Therapeutic Applications. Trends in Chemistry. 3: 523-534. PMID 35966501 DOI: 10.1016/j.trechm.2021.03.006  0.412
2021 Rogolino D, Naesens L, Bartoli J, Carcelli M, De Luca L, Pelosi G, Stokes RW, Van Berwaer R, Vittorio S, Stevaert A, Cohen SM. Exploration of the 2,3-dihydroisoindole pharmacophore for inhibition of the influenza virus PA endonuclease. Bioorganic Chemistry. 116: 105388. PMID 34670331 DOI: 10.1016/j.bioorg.2021.105388  0.468
2021 Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. Chemmedchem. PMID 33686743 DOI: 10.1002/cmdc.202100111  0.428
2021 Karges J, Stokes RW, Cohen SM. Correction: Photorelease of a metal-binding pharmacophore from a Ru(II) polypyridine complex. Dalton Transactions (Cambridge, England : 2003). PMID 33605968 DOI: 10.1039/d1dt90028e  0.372
2021 Karges J, Stokes RW, Cohen SM. Photorelease of a metal-binding pharmacophore from a Ru(II) polypyridine complex. Dalton Transactions (Cambridge, England : 2003). PMID 33564808 DOI: 10.1039/d0dt04290k  0.456
2020 Prosser KE, Stokes RW, Cohen SM. Evaluation of 3-Dimensionality in Approved and Experimental Drug Space. Acs Medicinal Chemistry Letters. 11: 1292-1298. PMID 32551014 DOI: 10.1021/Acsmedchemlett.0C00121  0.784
2020 Morrison CN, Prosser KE, Stokes RW, Cordes A, Metzler-Nolte N, Cohen SM. Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery Chemical Science. 11: 1216-1225. DOI: 10.1039/C9Sc05586J  0.753
2019 Morrison CN, Prosser KE, Stokes RW, Cordes A, Metzler-Nolte N, Cohen SM. Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery. Chemical Science. 11: 1216-1225. PMID 34123246 DOI: 10.1039/c9sc05586j  0.758
2019 Credille CV, Morrison CN, Stokes RW, Dick B, Feng Y, Sun J, Chen Y, Cohen SM. SAR Exploration of Tight Binding Inhibitors of Influenza Virus PA Endonuclease. Journal of Medicinal Chemistry. PMID 31536340 DOI: 10.1021/Acs.Jmedchem.9B00747  0.735
2019 Ence CC, Walker WK, Stokes RW, Martinez EE, Sarager SM, Smith SJ, Michaelis DJ. Synthesis of chiral titanium-containing phosphinoamide ligands for enantioselective heterobimetallic catalysis Tetrahedron. 75: 3341-3347. DOI: 10.1016/J.Tet.2019.04.063  0.528
2018 Credille CV, Dick B, Morrison CN, Stokes RW, Adamek R, Wu NC, Wilson IA, Cohen SM. Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. Journal of Medicinal Chemistry. PMID 30351002 DOI: 10.1021/acs.jmedchem.8b01363  0.736
2016 Talley MR, Stokes RW, Walker WK, Michaelis DJ. Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt-Ti catalysts. Dalton Transactions (Cambridge, England : 2003). PMID 27240482 DOI: 10.1039/C6Dt01783E  0.498
2015 Walker WK, Anderson DL, Stokes RW, Smith SJ, Michaelis DJ. Allylic aminations with hindered secondary amine nucleophiles catalyzed by heterobimetallic Pd-Ti complexes. Organic Letters. 17: 752-5. PMID 25612096 DOI: 10.1021/Acs.Orglett.5B00058  0.508
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