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Gavril W. Pasternak - Publications

Affiliations: 
1987-1990 Neurology Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
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353 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, ... ... Pasternak GW, et al. Oxidative Metabolism as a Modulator of Kratom's Biological Actions. Journal of Medicinal Chemistry. PMID 34783240 DOI: 10.1021/acs.jmedchem.1c01111  0.849
2021 Chakraborty S, Uprety R, Daibani AE, Rouzic VL, Hunkele A, Appourchaux K, Eans SO, Nuthikattu N, Jilakara R, Thammavong L, Pasternak GW, Pan YX, McLaughlin JP, Che T, Majumdar S. Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom. Acs Chemical Neuroscience. PMID 34213886 DOI: 10.1021/acschemneuro.1c00149  0.887
2021 Uprety R, Che T, Zaidi SA, Grinnell SG, Varga BR, Faouzi A, Slocum ST, Allaoa A, Varadi A, Nelson M, Bernhard SM, Kulko E, LeRouzic V, Eans SO, Simons CA, ... ... Pasternak GW, et al. Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site. Elife. 10. PMID 33555255 DOI: 10.7554/eLife.56519  0.881
2020 Narayan A, Hunkele A, Xu J, Bassoni DL, Pasternak GW, Pan YX. Correction to: Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1. Cellular and Molecular Neurobiology. PMID 33128690 DOI: 10.1007/s10571-020-00990-4  0.811
2020 Narayan A, Hunkle A, Xu J, Bassoni DL, Pasternak GW, Pan YX. Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1. Cellular and Molecular Neurobiology. PMID 33033993 DOI: 10.1007/s10571-020-00973-5  0.787
2020 Grinnell SG, Uprety R, Varadi A, Subrath J, Hunkele A, Pan YX, Pasternak GW, Majumdar S. Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain. Cellular and Molecular Neurobiology. PMID 32424771 DOI: 10.1007/S10571-020-00867-6  0.886
2020 Baumann MH, Pasternak GW, Negus SS. Confronting the opioid crisis with basic research in neuropharmacology. Neuropharmacology. 107972. PMID 31958407 DOI: 10.1016/J.Neuropharm.2020.107972  0.616
2019 Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, van Rijn RM. G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder. British Journal of Pharmacology. PMID 31705528 DOI: 10.1111/Bph.14913  0.764
2019 Pasternak GW, Childers SR, Pan YX. Emerging Insights into Mu Opioid Pharmacology. Handbook of Experimental Pharmacology. PMID 31598835 DOI: 10.1007/164_2019_270  0.84
2019 Kruegel AC, Uprety R, Grinnell SG, Langreck C, Pekarskaya EA, Le Rouzic V, Ansonoff M, Gassaway MM, Pintar JE, Pasternak GW, Javitch JA, Majumdar S, Sames D. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. Acs Central Science. 5: 992-1001. PMID 31263758 DOI: 10.1021/Acscentsci.9B00141  0.883
2019 Irie T, Shum R, Deni I, Hunkele A, Le Rouzic V, Xu J, Wilson R, Fischer G, Pasternak GW, Pan YX. Identification of abundant and evolutionarily conserved opioid receptor circular RNAs in the nervous system moduated by morphine. Molecular Pharmacology. PMID 31243060 DOI: 10.1124/Mol.118.113977  0.851
2019 Gangangari KK, Váradi A, Majumdar S, Larson SM, Pasternak GW, Pillarsetty NK. Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([I]IPAG). Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 31165385 DOI: 10.1007/S11307-019-01369-8  0.668
2019 Atigari DV, Uprety R, Pasternak GW, Majumdar S, Kivell BM. MP1104, a mixed kappa-delta opioid receptor agonist has anti-cocaine properties with reduced side-effects in rats. Neuropharmacology. PMID 30768946 DOI: 10.1016/J.Neuropharm.2019.02.010  0.727
2019 Hu X, Wang Y, Hunkele A, Provasi D, Pasternak GW, Filizola M. Kinetic and thermodynamic insights into sodium ion translocation through the μ-opioid receptor from molecular dynamics and machine learning analysis. Plos Computational Biology. 15: e1006689. PMID 30677023 DOI: 10.1371/Journal.Pcbi.1006689  0.47
2019 Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, Rijn RMv. Therapeutic Potential of G-protein-Biased Kratom-Derived and Synthetic Carfentanil-Amide Opioids for Alcohol Use Disorder The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.498.3  0.496
2018 Uprety R, Váradi A, Allaoa A, Redel-Traub GN, Palmer TC, Feinberg EN, Ferris AC, Pande VS, Pasternak GW, Majumdar S. Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ) receptor selective ligands. European Journal of Medicinal Chemistry. 164: 241-251. PMID 30597325 DOI: 10.1016/J.Ejmech.2018.12.048  0.71
2018 Kim FJ, Pasternak GW. σ Receptor ligand binding: an open-and-shut case. Nature Structural & Molecular Biology. PMID 30310147 DOI: 10.1038/S41594-018-0146-1  0.426
2018 Davis MP, Pasternak G, Behm B. Treating Chronic Pain: An Overview of Clinical Studies Centered on the Buprenorphine Option. Drugs. PMID 30051169 DOI: 10.1007/S40265-018-0953-Z  0.687
2018 Le Rouzic V, Narayan A, Hunkle A, Marrone GF, Lu Z, Majumdar S, Xu J, Pan YX, Pasternak GW. Pharmacological Characterization of Levorphanol, a G-Protein Biased Opioid Analgesic. Anesthesia and Analgesia. PMID 29649035 DOI: 10.1213/Ane.0000000000003360  0.869
2018 Pasternak GW, Coyle JT, Enna SJ. Preface. Advances in Pharmacology (San Diego, Calif.). 82: xv-xx. PMID 29413530 DOI: 10.1016/S1054-3589(18)30008-5  0.347
2018 Pasternak GW. Mu Opioid Pharmacology: 40 Years to the Promised Land. Advances in Pharmacology (San Diego, Calif.). 82: 261-291. PMID 29413524 DOI: 10.1016/Bs.Apha.2017.09.006  0.704
2018 Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, ... ... Pasternak GW, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011  0.809
2018 Baumann MH, Pasternak GW. Novel Synthetic Opioids and Overdose Deaths: Tip of the Iceberg? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 216-217. PMID 29192657 DOI: 10.1038/Npp.2017.211  0.571
2017 Huang XP, Che T, Mangano TJ, Le Rouzic V, Pan YX, Cameron MD, Baumann MH, Pasternak GW, Roth BL. Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo. Jci Insight. 2. PMID 29202454 DOI: 10.1172/Jci.Insight.97222  0.81
2017 Lu Z, Xu J, Xu M, Rossi GC, Majumdar S, Pasternak GW, Pan YX. Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia. Anesthesia and Analgesia. PMID 28991118 DOI: 10.1213/Ane.0000000000002538  0.869
2017 Baumann MH, Majumdar S, Le Rouzic V, Hunkele A, Uprety R, Huang XP, Xu J, Roth BL, Pan YX, Pasternak GW. Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace. Neuropharmacology. PMID 28807672 DOI: 10.1016/J.Neuropharm.2017.08.016  0.883
2017 Pasternak GW. Allosteric Modulation of Opioid G-Protein Coupled Receptors by Sigma1 Receptors. Handbook of Experimental Pharmacology. PMID 28667477 DOI: 10.1007/164_2017_34  0.624
2017 Kim FJ, Pasternak GW. Cloning the sigma2 receptor: Wandering 40 years to find an identity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28645899 DOI: 10.1073/Pnas.1708155114  0.606
2017 Urai Á, Váradi A, Szőcs L, Komjáti B, Le Rouzic V, Hunkele A, Pasternak GW, Majumdar S, Hosztafi S. Synthesis and pharmacological evaluation of novel selective MOR agonist 6β-pyridinyl amidomorphines exhibiting long-lasting antinociception. Medchemcomm. 8: 152-157. PMID 28603600 DOI: 10.1039/C6Md00450D  0.744
2017 Pan L, Pasternak DA, Xu J, Xu M, Lu Z, Pasternak GW, Pan YX. Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1. Plos One. 12: e0174694. PMID 28350844 DOI: 10.1371/Journal.Pone.0174694  0.761
2017 Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan YX, Pasternak GW. Genetic dissociation of morphine analgesia from hyperalgesia in mice. Psychopharmacology. PMID 28343361 DOI: 10.1007/S00213-017-4600-2  0.888
2017 Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, et al. Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. The Journal of Clinical Investigation. PMID 28319053 DOI: 10.1172/Jci88760  0.871
2016 Marrone GF, Lu Z, Rossi G, Narayan A, Hunkele A, Marx S, Xu J, Pintar J, Majumdar S, Pan YX, Pasternak GW. Tetrapeptide endomorphin analogs require both full length and truncated splice variants of the mu opioid receptor gene Oprm1 for analgesia. Acs Chemical Neuroscience. PMID 27648914 DOI: 10.1021/Acschemneuro.6B00240  0.88
2016 Váradi A, Marrone GF, Palmer TC, Narayan A, Szabó MR, Le Rouzic V, Grinnell SG, Subrath JJ, Warner E, Kalra S, Hunkele A, Pagirsky J, Eans SO, Medina JM, Xu J, ... ... Pasternak GW, et al. Mitragynine/corynantheidine pseudoindoxyls as opioid analgesics with mu agonism and delta antagonism which do not recruit β-arrestin-2. Journal of Medicinal Chemistry. PMID 27556704 DOI: 10.1021/Acs.Jmedchem.6B00748  0.888
2016 Grinnell SG, Ansonoff M, Marrone GF, Lu Z, Narayan A, Xu J, Rossi G, Majumdar S, Pan YX, Bassoni DL, Pintar J, Pasternak G. Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants. Synapse (New York, N.Y.). PMID 27223691 DOI: 10.1002/Syn.21914  0.872
2016 Marrone GF, Grinnell SG, Lu Z, Rossi GC, Le Rouzic V, Xu J, Majumdar S, Pan YX, Pasternak GW. Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976581 DOI: 10.1073/Pnas.1523894113  0.879
2015 Váradi A, Marrone GF, Eans SO, Ganno ML, Subrath JJ, Le Rouzic V, Hunkele A, Pasternak GW, McLaughlin JP, Majumdar S. Synthesis and Characterization of a Dual Kappa-Delta Opioid Receptor Agonist Analgesic Blocking Cocaine Reward Behavior. Acs Chemical Neuroscience. PMID 26325040 DOI: 10.1021/Acschemneuro.5B00153  0.863
2015 Marrone GF, Majumdar S, Pasternak GW. Radioligand Binding Assay for an Exon 11-Associated Mu Opioid Receptor Target. Methods in Molecular Biology (Clifton, N.J.). 1335: 241-9. PMID 26260605 DOI: 10.1007/978-1-4939-2914-6_16  0.853
2015 Varadi A, Palmer TC, Haselton N, Afonin D, Subrath JJ, LeRouzic V, Hunkele A, Pasternak GW, Marrone GF, Borics A, Majumdar S. Synthesis of carfentanil amide opioids using the Ugi multicomponent reaction. Acs Chemical Neuroscience. PMID 26148793 DOI: 10.1021/Acschemneuro.5B00137  0.858
2015 Lu Z, Xu J, Rossi GC, Majumdar S, Pasternak GW, Pan YX. Mediation of opioid analgesia by a truncated 6-transmembrane GPCR. The Journal of Clinical Investigation. PMID 26011641 DOI: 10.1172/Jci81070  0.896
2015 Pescatore R, Marrone GF, Sedberry S, Vinton D, Finkelstein N, Katlowitz YE, Pasternak GW, Wilson KR, Majumdar S. Synthesis and Pharmacology of Halogenated δ-Opioid-Selective [d-Ala(2)]Deltorphin II Peptide Analogues. Acs Chemical Neuroscience. 6: 905-10. PMID 25844930 DOI: 10.1021/Acschemneuro.5B00060  0.851
2015 Pickett JE, Váradi A, Palmer TC, Grinnell SG, Schrock JM, Pasternak GW, Karimov RR, Majumdar S. Mild, Pd-catalyzed stannylation of radioiodination targets. Bioorganic & Medicinal Chemistry Letters. 25: 1761-4. PMID 25777268 DOI: 10.1016/J.Bmcl.2015.02.055  0.756
2015 Xu J, Faskowitz AJ, Rossi GC, Xu M, Lu Z, Pan YX, Pasternak GW. Stabilization of morphine tolerance with long-term dosing: association with selective upregulation of mu-opioid receptor splice variant mRNAs. Proceedings of the National Academy of Sciences of the United States of America. 112: 279-84. PMID 25535370 DOI: 10.1073/Pnas.1419183112  0.864
2014 Xu J, Lu Z, Xu M, Rossi GC, Kest B, Waxman AR, Pasternak GW, Pan YX. Differential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strains. Plos One. 9: e111267. PMID 25343478 DOI: 10.1371/Journal.Pone.0111267  0.83
2014 Xu J, Lu Z, Xu M, Pan L, Deng Y, Xie X, Liu H, Ding S, Hurd YL, Pasternak GW, Klein RJ, Cartegni L, Zhou W, Pan YX. A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11048-66. PMID 25122903 DOI: 10.1523/Jneurosci.3986-13.2014  0.696
2014 Wieskopf JS, Pan YX, Marcovitz J, Tuttle AH, Majumdar S, Pidakala J, Pasternak GW, Mogil JS. Broad-spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene. Pain. 155: 2063-70. PMID 25093831 DOI: 10.1016/J.Pain.2014.07.014  0.873
2014 Shang Y, LeRouzic V, Schneider S, Bisignano P, Pasternak GW, Filizola M. Mechanistic insights into the allosteric modulation of opioid receptors by sodium ions. Biochemistry. 53: 5140-9. PMID 25073009 DOI: 10.1021/Bi5006915  0.461
2014 Grinnell SG, Majumdar S, Narayan A, Le Rouzic V, Ansonoff M, Pintar JE, Pasternak GW. Pharmacologic characterization in the rat of a potent analgesic lacking respiratory depression, IBNtxA. The Journal of Pharmacology and Experimental Therapeutics. 350: 710-8. PMID 24970924 DOI: 10.1124/Jpet.114.213199  0.857
2014 Kim C, Barbut D, Heinemann MH, Pasternak G, Rosenblatt MI. Synthetic neurotensin analogues are nontoxic analgesics for the rabbit cornea. Investigative Ophthalmology & Visual Science. 55: 3586-93. PMID 24825106 DOI: 10.1167/Iovs.13-13050  0.481
2014 Pasternak GW. Opiate pharmacology and relief of pain. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1655-61. PMID 24799496 DOI: 10.1200/Jco.2013.53.1079  0.56
2014 Váradi A, Palmer TC, Notis PR, Redel-Traub GN, Afonin D, Subrath JJ, Pasternak GW, Hu C, Sharma I, Majumdar S. Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping. Organic Letters. 16: 1668-71. PMID 24580074 DOI: 10.1021/Ol500328T  0.613
2014 Xu J, Xu M, Bolan E, Gilbert AK, Pasternak GW, Pan YX. Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P. Synapse (New York, N.Y.). 68: 144-52. PMID 24375714 DOI: 10.1002/Syn.21727  0.861
2014 Lu Z, Xu J, Xu M, Pasternak GW, Pan YX. Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107. Molecular Pharmacology. 85: 368-80. PMID 24302561 DOI: 10.1124/Mol.113.089292  0.72
2014 Pasternak GW. Opioids and their receptors: Are we there yet? Neuropharmacology. 76: 198-203. PMID 23624289 DOI: 10.1016/J.Neuropharm.2013.03.039  0.696
2014 Shang Y, Le Rouzic V, Pasternak GW, Filizola M. A Molecular-Level Investigation of the Effect of Sodium Ions on the Binding of Opioid Ligands to their Receptors Biophysical Journal. 106: 105a. DOI: 10.1016/J.Bpj.2013.11.649  0.519
2013 Váradi A, Hosztafi S, Le Rouzic V, Tóth G, Urai Á, Noszál B, Pasternak GW, Grinnell SG, Majumdar S. Novel 6β-acylaminomorphinans with analgesic activity. European Journal of Medicinal Chemistry. 69: 786-9. PMID 24103580 DOI: 10.1016/J.Ejmech.2013.09.031  0.878
2013 Pasternak GW, Pan YX. Mu opioids and their receptors: evolution of a concept. Pharmacological Reviews. 65: 1257-317. PMID 24076545 DOI: 10.1124/Pr.112.007138  0.821
2013 Pickett JE, Nagakura K, Pasternak AR, Grinnell SG, Majumdar S, Lewis JS, Pasternak GW. Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin. Bioorganic & Medicinal Chemistry Letters. 23: 4347-50. PMID 23796454 DOI: 10.1016/J.Bmcl.2013.05.090  0.851
2013 Xu J, Xu M, Brown T, Rossi GC, Hurd YL, Inturrisi CE, Pasternak GW, Pan YX. Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. The Journal of Biological Chemistry. 288: 21211-27. PMID 23760268 DOI: 10.1074/Jbc.M113.458687  0.873
2013 Su W, Pasternak GW. The role of multidrug resistance-associated protein in the blood-brain barrier and opioid analgesia. Synapse (New York, N.Y.). 67: 609-19. PMID 23508590 DOI: 10.1002/Syn.21667  0.436
2013 Faskowitz AJ, Kramskiy VN, Pasternak GW. Methadone-induced hypoglycemia. Cellular and Molecular Neurobiology. 33: 537-42. PMID 23467779 DOI: 10.1007/S10571-013-9919-6  0.546
2012 Kim FJ, Schrock JM, Spino CM, Marino JC, Pasternak GW. Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression Biochemical and Biophysical Research Communications. 426: 177-182. PMID 22925888 DOI: 10.1016/J.Bbrc.2012.08.052  0.331
2012 Majumdar S, Subrath J, Le Rouzic V, Polikar L, Burgman M, Nagakura K, Ocampo J, Haselton N, Pasternak AR, Grinnell S, Pan YX, Pasternak GW. Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants. Journal of Medicinal Chemistry. 55: 6352-62. PMID 22734622 DOI: 10.1021/Jm300305C  0.865
2012 Pasternak GW. Preclinical pharmacology and opioid combinations. Pain Medicine (Malden, Mass.). 13: S4-11. PMID 22420604 DOI: 10.1111/J.1526-4637.2012.01335.X  0.658
2011 Majumdar S, Grinnell S, Le Rouzic V, Burgman M, Polikar L, Ansonoff M, Pintar J, Pan YX, Pasternak GW. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects. Proceedings of the National Academy of Sciences of the United States of America. 108: 19778-83. PMID 22106286 DOI: 10.1073/Pnas.1115231108  0.871
2011 El Maarouf A, Kolesnikov Y, Pasternak G, Rutishauser U. Removal of polysialylated neural cell adhesion molecule increases morphine analgesia and interferes with tolerance in mice. Brain Research. 1404: 55-62. PMID 21704981 DOI: 10.1016/J.Brainres.2011.06.021  0.577
2011 Majumdar S, Burgman M, Haselton N, Grinnell S, Ocampo J, Pasternak AR, Pasternak GW. Generation of novel radiolabeled opiates through site-selective iodination. Bioorganic & Medicinal Chemistry Letters. 21: 4001-4. PMID 21621410 DOI: 10.1016/J.Bmcl.2011.05.008  0.863
2011 Pasternak G, Pan YX. Mu opioid receptors in pain management Acta Anaesthesiologica Taiwanica. 49: 21-25. PMID 21453899 DOI: 10.1016/J.Aat.2010.12.008  0.825
2011 Pasternak GW, Pan YX. Mix and match: heterodimers and opioid tolerance. Neuron. 69: 6-8. PMID 21318174 DOI: 10.1016/J.Neuron.2010.12.030  0.826
2011 Xu J, Xu M, Rossi GC, Pasternak GW, Pan YX. Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1. Molecular Pain. 7: 9. PMID 21255438 DOI: 10.1186/1744-8069-7-9  0.88
2011 Pan YX, Grinnell S, Pasternak GW. Alternative Pre-mRNA splicing of G protein-coupled receptors Neuromethods. 60: 19-34. DOI: 10.1007/978-1-61779-179-6_2  0.806
2010 Rossi GC, Matulonis JE, Richelson E, Barbut D, Pasternak GW. Systemically and topically active antinociceptive neurotensin compounds. The Journal of Pharmacology and Experimental Therapeutics. 334: 1075-9. PMID 20576795 DOI: 10.1124/Jpet.109.165282  0.782
2010 Kolesnikov YA, Oksman G, Pasternak GW. Topical methadone and meperidine analgesic synergy in the mouse. European Journal of Pharmacology. 638: 61-4. PMID 20433826 DOI: 10.1016/J.Ejphar.2010.04.020  0.608
2010 Kim FJ, Kovalyshyn I, Burgman M, Neilan C, Chien CC, Pasternak GW. Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding. Molecular Pharmacology. 77: 695-703. PMID 20089882 DOI: 10.1124/Mol.109.057083  0.67
2010 Pasternak GW. Molecular insights into mu opioid pharmacology: From the clinic to the bench. The Clinical Journal of Pain. 26: S3-9. PMID 20026962 DOI: 10.1097/Ajp.0B013E3181C49D2E  0.703
2009 Kolesnikov YA, Chereshnev I, Criesta M, Pan YX, Pasternak GW. Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice. Brain Research. 1289: 14-21. PMID 19545548 DOI: 10.1016/J.Brainres.2009.06.041  0.687
2009 Hadjimarkou MM, Abbadie C, Kasselman LJ, Pan YX, Pasternak GW, Bodnar RJ. Changes in mouse mu opioid receptor Exon 7/8-like immunoreactivity following food restriction and food deprivation in rats. Synapse (New York, N.Y.). 63: 585-97. PMID 19301417 DOI: 10.1002/Syn.20639  0.735
2009 Pan YX, Xu J, Xu M, Rossi GC, Matulonis JE, Pasternak GW. Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions. Proceedings of the National Academy of Sciences of the United States of America. 106: 4917-22. PMID 19273844 DOI: 10.1073/Pnas.0811586106  0.887
2009 Chou R, Fanciullo GJ, Fine PG, Adler JA, Ballantyne JC, Davies P, Donovan MI, Fishbain DA, Foley KM, Fudin J, Gilson AM, Kelter A, Mauskop A, O'Connor PG, Passik SD, ... Pasternak GW, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. The Journal of Pain : Official Journal of the American Pain Society. 10: 113-30. PMID 19187889 DOI: 10.1016/J.Jpain.2008.10.008  0.547
2009 Xu J, Xu M, Hurd YL, Pasternak GW, Pan YX. Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene. Journal of Neurochemistry. 108: 962-72. PMID 19077058 DOI: 10.1111/J.1471-4159.2008.05833.X  0.801
2007 Pasternak GW. When it comes to opiates, just say NO. The Journal of Clinical Investigation. 117: 3185-7. PMID 17975665 DOI: 10.1172/Jci34035  0.539
2007 Mei J, Pasternak GW. Modulation of brainstem opiate analgesia in the rat by sigma 1 receptors: a microinjection study. The Journal of Pharmacology and Experimental Therapeutics. 322: 1278-85. PMID 17545312 DOI: 10.1124/Jpet.107.121137  0.663
2007 Kolesnikov Y, El-Maarouf A, El-Maarouf Abderrahman A, Rutishauser U, Rutinhauser U, Pasternak G. Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: correlation with morphine and lidocaine analgesia. European Journal of Pharmacology. 568: 124-33. PMID 17543299 DOI: 10.1016/J.Ejphar.2007.04.045  0.354
2007 Pasternak GW. Opioid receptors in pain control Journal of Supportive Oncology. 5: 61. PMID 17348356  0.483
2007 Callahan P, Pasternak GW. Opiates, opioid peptides, and their receptors. Journal of Cardiothoracic Anesthesia. 1: 569-76. PMID 17165358 DOI: 10.1016/0888-6296(87)90046-9  0.595
2007 Kim FJ, Kovalyshyn I, Nielan C, Pasternak GW. Sigma selective antagonists potentiate G‐protein coupled receptor signaling without altering receptor occupancy The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a425  0.322
2007 Pasternak GW. σ1 receptors and the modulation of opiate analgesics Sigma Receptors: Chemistry, Cell Biology and Clinical Implications. 337-350. DOI: 10.1007/978-0-387-36514-5_16  0.504
2006 Milo S, Ansonoff M, King M, Rossi GC, Zuckerman A, Pintar J, Pasternak GW. Codeine and 6-acetylcodeine analgesia in mice. Cellular and Molecular Neurobiology. 26: 1011-9. PMID 16868817 DOI: 10.1007/S10571-006-9101-5  0.87
2006 Mahurter L, Garceau C, Marino J, Schmidhammer H, Tóth G, Pasternak GW. Separation of binding affinity and intrinsic activity of the potent mu-opioid 14-methoxymetopon. The Journal of Pharmacology and Experimental Therapeutics. 319: 247-53. PMID 16801454 DOI: 10.1124/Jpet.106.105395  0.544
2006 Zhang Y, Pan YX, Kolesnikov Y, Pasternak GW. Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system. Brain Research. 1099: 33-43. PMID 16793025 DOI: 10.1016/J.Brainres.2006.04.133  0.513
2005 Yang K, Zuckerman A, Pasternak GW. Affinity labeling mu opioid receptors with novel radioligands. Cellular and Molecular Neurobiology. 25: 759-65. PMID 16075389 DOI: 10.1007/S10571-005-3973-7  0.59
2005 Levin E, Premkumar A, Veenman L, Kugler W, Leschiner S, Spanier I, Weisinger G, Lakomek M, Weizman A, Snyder SH, Pasternak GW, Gavish M. The peripheral-type benzodiazepine receptor and tumorigenicity: isoquinoline binding protein (IBP) antisense knockdown in the C6 glioma cell line. Biochemistry. 44: 9924-35. PMID 16026165 DOI: 10.1021/Bi050150S  0.44
2005 Israel Y, Kandov Y, Khaimova E, Kest A, Lewis SR, Pasternak GW, Pan YX, Rossi GC, Bodnar RJ. NPY-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats. Peptides. 26: 1167-75. PMID 15949635 DOI: 10.1016/J.Peptides.2005.01.017  0.684
2005 Pan YX, Xu J, Bolan E, Moskowitz HS, Xu M, Pasternak GW. Identification of four novel exon 5 splice variants of the mouse mu-opioid receptor gene: functional consequences of C-terminal splicing. Molecular Pharmacology. 68: 866-75. PMID 15939800 DOI: 10.1124/Mol.105.011858  0.865
2005 Pasternak GW. Molecular biology of opioid analgesia. Journal of Pain and Symptom Management. 29: S2-9. PMID 15907642 DOI: 10.1016/J.Jpainsymman.2005.01.011  0.686
2005 Pan L, Xu J, Yu R, Xu MM, Pan YX, Pasternak GW. Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm. Neuroscience. 133: 209-20. PMID 15893644 DOI: 10.1016/J.Neuroscience.2004.12.033  0.699
2005 Zelcer S, Kolesnikov Y, Kovalyshyn I, Pasternak DA, Pasternak GW. Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs. Brain Research. 1040: 151-6. PMID 15804436 DOI: 10.1016/J.Brainres.2005.01.070  0.581
2004 Pasternak DA, Pan L, Xu J, Yu R, Xu MM, Pasternak GW, Pan YX. Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy. Journal of Neurochemistry. 91: 881-90. PMID 15525342 DOI: 10.1111/J.1471-4159.2004.02767.X  0.807
2004 Pasternak GW. Multiple opiate receptors: déjà vu all over again. Neuropharmacology. 47: 312-23. PMID 15464147 DOI: 10.1016/J.Neuropharm.2004.07.004  0.699
2004 Hadjimarkou MM, Singh A, Kandov Y, Israel Y, Pan YX, Rossi GC, Pasternak GW, Bodnar RJ. Opioid receptor involvement in food deprivation-induced feeding: evaluation of selective antagonist and antisense oligodeoxynucleotide probe effects in mice and rats. The Journal of Pharmacology and Experimental Therapeutics. 311: 1188-202. PMID 15333676 DOI: 10.1124/Jpet.104.071761  0.64
2004 Abbadie C, Pan YX, Pasternak GW. Immunohistochemical study of the expression of exon11-containing mu opioid receptor variants in mouse brain. Neuroscience. 127: 419-30. PMID 15262332 DOI: 10.1016/j.neuroscience.2004.03.033  0.441
2004 Gilbert AK, Hosztafi S, Mahurter L, Pasternak GW. Pharmacological characterization of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin analgesia and their differentiation from morphine. European Journal of Pharmacology. 492: 123-30. PMID 15178355 DOI: 10.1016/J.Ejphar.2004.03.050  0.679
2004 Bolan EA, Pan YX, Pasternak GW. Functional analysis of MOR-1 splice variants of the mouse mu opioid receptor gene Oprm. Synapse (New York, N.Y.). 51: 11-8. PMID 14579421 DOI: 10.1002/Syn.10277  0.869
2003 Kolesnikov YA, Wilson RS, Pasternak GW. The synergistic analgesic interactions between hydrocodone and ibuprofen. Anesthesia and Analgesia. 97: 1721-3. PMID 14633549 DOI: 10.1213/01.Ane.0000087801.20395.97  0.376
2003 Kolesnikov YA, Cristea M, Pasternak GW. Analgesic synergy between topical morphine and butamben in mice. Anesthesia and Analgesia. 97: 1103-7, table of con. PMID 14500165 DOI: 10.1213/01.Ane.0000081060.63296.A8  0.554
2003 Hadjimarkou MM, Khaimova E, Pan YX, Rossi GC, Pasternak GW, Bodnar RJ. Feeding induced by food deprivation is differentially reduced by opioid receptor antisense oligodeoxynucleotide probes in rats. Brain Research. 987: 223-32. PMID 14499967 DOI: 10.1016/S0006-8993(03)03342-0  0.481
2003 Neilan CL, King MA, Rossi G, Ansonoff M, Pintar JE, Schiller PW, Pasternak GW. Differential sensitivities of mouse strains to morphine and [Dmt1]DALDA analgesia. Brain Research. 974: 254-7. PMID 12742645 DOI: 10.1016/S0006-8993(03)02590-3  0.853
2003 Snyder SH, Pasternak GW. Historical review: Opioid receptors. Trends in Pharmacological Sciences. 24: 198-205. PMID 12707007 DOI: 10.1016/S0165-6147(03)00066-X  0.684
2003 Neilan CL, Janvey AJ, Bolan E, Berezowska I, Nguyen TM, Schiller PW, Pasternak GW. Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide. The Journal of Pharmacology and Experimental Therapeutics. 306: 430-6. PMID 12663687 DOI: 10.1124/Jpet.103.049742  0.841
2003 Harrison BA, Pasternak GW, Verdine GL. 2,6-Dimethyltyrosine analogues of a stereodiversified ligand library: highly potent, selective, non-peptidic mu opioid receptor agonists. Journal of Medicinal Chemistry. 46: 677-80. PMID 12593647 DOI: 10.1021/Jm025608S  0.612
2003 Pan YX, Xu J, Mahurter L, Xu M, Gilbert AK, Pasternak GW. Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X. Biochemical and Biophysical Research Communications. 301: 1057-61. PMID 12589820 DOI: 10.1016/S0006-291X(03)00089-5  0.785
2003 King MA, Su W, Nielan CL, Chang AH, Schütz J, Schmidhammer H, Pasternak GW. 14-Methoxymetopon, a very potent mu-opioid receptor-selective analgesic with an unusual pharmacological profile. European Journal of Pharmacology. 459: 203-9. PMID 12524147 DOI: 10.1016/S0014-2999(02)02821-2  0.694
2002 Nitsche JF, Schuller AG, King MA, Zengh M, Pasternak GW, Pintar JE. Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10906-13. PMID 12486185  0.575
2002 Hadjimarkou MM, Silva RM, Rossi GC, Pasternak GW, Bodnar RJ. Feeding induced by food deprivation is differentially reduced by G-protein alpha-subunit antisense probes in rats. Brain Research. 955: 45-54. PMID 12419520 DOI: 10.1016/S0006-8993(02)03361-9  0.718
2002 Harrison BA, Gierasch TM, Neilan C, Pasternak GW, Verdine GL. High-affinity mu opioid receptor ligands discovered by the screening of an exhaustively stereodiversified library of 1,5-enediols. Journal of the American Chemical Society. 124: 13352-3. PMID 12418865 DOI: 10.1021/Ja027150P  0.624
2002 Bolan EA, Tallarida RJ, Pasternak GW. Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 303: 557-62. PMID 12388636 DOI: 10.1124/Jpet.102.035881  0.862
2002 Abbadie C, Rossi GC, Orciuolo A, Zadina JE, Pasternak GW. Anatomical and functional correlation of the endomorphins with mu opioid receptor splice variants. The European Journal of Neuroscience. 16: 1075-82. PMID 12383236 DOI: 10.1046/J.1460-9568.2002.02173.X  0.652
2002 Pan YX, Bolan E, Pasternak GW. Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype. Biochemical and Biophysical Research Communications. 297: 659-63. PMID 12270145 DOI: 10.1016/S0006-291X(02)02258-1  0.885
2002 Silva RM, Grossman HC, Rossi GC, Pasternak GW, Bodnar RJ. Pharmacological characterization of beta-endorphin- and dynorphin A(1-17)-induced feeding using G-protein alpha-subunit antisense probes in rats. Peptides. 23: 1101-6. PMID 12126737 DOI: 10.1016/S0196-9781(02)00036-0  0.722
2002 Silva RM, Grossman HC, Hadjimarkou MM, Rossi GC, Pasternak GW, Bodnar RJ. Dynorphin A(1-17)-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats. The Journal of Pharmacology and Experimental Therapeutics. 301: 513-8. PMID 11961051 DOI: 10.1124/Jpet.301.2.513  0.875
2002 Mei J, Pasternak GW. Sigma1 receptor modulation of opioid analgesia in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 300: 1070-4. PMID 11861817 DOI: 10.1124/Jpet.300.3.1070  0.614
2002 Rossi GC, Pellegrino M, Shane R, Abbadie CA, Dustman J, Jimenez C, Bodnar RJ, Pasternak GW, Allen RG. Characterization of rat prepro-orphanin FQ/nociceptin((154-181)): nociceptive processing in supraspinal sites. The Journal of Pharmacology and Experimental Therapeutics. 300: 257-64. PMID 11752124 DOI: 10.1124/Jpet.300.1.257  0.785
2002 Nitsche JF, Schuller AGP, King MA, Zengh M, Pasternak GW, Pintar JE. Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice The Journal of Neuroscience. 22: 10906-10913. DOI: 10.1523/Jneurosci.22-24-10906.2002  0.642
2002 Abbadie C, Pasternak GW. Chapter I Opioid receptors Handbook of Chemical Neuroanatomy. 20: 1-29. DOI: 10.1016/S0924-8196(02)80003-3  0.607
2002 Pan Y, Bolan E, Pasternak GW. Erratum to “Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype” [Biochem. Biophys. Res. Commun. 297 (2002) 659–663] Biochemical and Biophysical Research Communications. 298: 456. DOI: 10.1016/S0006-291X(02)02479-8  0.863
2001 Pan YX, Xu J, Mahurter L, Bolan E, Xu M, Pasternak GW. Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene. Proceedings of the National Academy of Sciences of the United States of America. 98: 14084-9. PMID 11717463 DOI: 10.1073/Pnas.241296098  0.811
2001 Abbadie C, Pasternak GW, Aicher SA. Presynaptic localization of the carboxy-terminus epitopes of the mu opioid receptor splice variants MOR-1C and MOR-1D in the superficial laminae of the rat spinal cord. Neuroscience. 106: 833-42. PMID 11682168 DOI: 10.1016/S0306-4522(01)00317-7  0.359
2001 Abbadie C, Pasternak GW. Differential in vivo internalization of MOR-1 and MOR-1C by morphine. Neuroreport. 12: 3069-72. PMID 11568638 DOI: 10.1097/00001756-200110080-00017  0.642
2001 King MA, Bradshaw S, Chang AH, Pintar JE, Pasternak GW. Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7788-92. PMID 11567069 DOI: 10.1523/Jneurosci.21-19-07788.2001  0.636
2001 Mogil JS, Pasternak GW. The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacological Reviews. 53: 381-415. PMID 11546835  0.46
2001 Pasternak GW. The pharmacology of mu analgesics: from patients to genes. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 220-31. PMID 11499401 DOI: 10.1177/107385840100700307  0.688
2001 Mei J, Pasternak GW. Molecular cloning and pharmacological characterization of the rat sigma1 receptor. Biochemical Pharmacology. 62: 349-55. PMID 11434908 DOI: 10.1016/S0006-2952(01)00666-9  0.423
2001 Shane R, Lazar DA, Rossi GC, Pasternak GW, Bodnar RJ. Analgesia elicited by OFQ/nociceptin and its fragments from the amygdala in rats. Brain Research. 907: 109-16. PMID 11430891 DOI: 10.1016/S0006-8993(01)02612-9  0.472
2001 Pasternak GW. Insights into mu opioid pharmacology the role of mu opioid receptor subtypes. Life Sciences. 68: 2213-9. PMID 11368076 DOI: 10.1016/S0024-3205(01)01008-6  0.698
2001 Neilan CL, Nguyen TM, Schiller PW, Pasternak GW. Pharmacological characterization of the dermorphin analog [Dmt(1)]DALDA, a highly potent and selective mu-opioid peptide. European Journal of Pharmacology. 419: 15-23. PMID 11348625 DOI: 10.1016/S0014-2999(01)00946-3  0.674
2001 Cherny N, Ripamonti C, Pereira J, Davis C, Fallon M, McQuay H, Mercadante S, Pasternak G, Ventafridda V. Strategies to manage the adverse effects of oral morphine: an evidence-based report. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2542-54. PMID 11331334 DOI: 10.1200/jco.2001.19.9.2542  0.408
2001 Silva RM, Hadjimarkou MM, Rossi GC, Pasternak GW, Bodnar RJ. Beta-endorphin-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 590-6. PMID 11303047  0.487
2001 Mathis JP, Rossi GC, Pellegrino MJ, Jimenez C, Pasternak GW, Allen RG. Carboxyl terminal peptides derived from prepro-orphanin FQ/nociceptin (ppOFQ/N) are produced in the hypothalamus and possess analgesic bioactivities. Brain Research. 895: 89-94. PMID 11259764 DOI: 10.1016/S0006-8993(01)02035-2  0.461
2001 King M, Su W, Chang A, Zuckerman A, Pasternak GW. Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs. Nature Neuroscience. 4: 268-74. PMID 11224543 DOI: 10.1038/85115  0.492
2001 Pasternak GW. Incomplete cross tolerance and multiple mu opioid peptide receptors. Trends in Pharmacological Sciences. 22: 67-70. PMID 11166849 DOI: 10.1016/S0165-6147(00)01616-3  0.608
2001 Mathis JP, Mandyam CD, Altememi GF, Pasternak GW, Standifer KM. Orphanin FQ/nociceptin and naloxone benzoylhydrazone activate distinct receptors in BE(2)-C human neuroblastoma cells. Neuroscience Letters. 299: 173-6. PMID 11165763 DOI: 10.1016/S0304-3940(01)01524-5  0.636
2000 Kolesnikov YA, Chereshnev I, Pasternak GW. Analgesic synergy between topical lidocaine and topical opioids. The Journal of Pharmacology and Experimental Therapeutics. 295: 546-51. PMID 11046087  0.547
2000 Abbadie C, Pan Y, Drake CT, Pasternak GW. Comparative immunohistochemical distributions of carboxy terminus epitopes from the mu-opioid receptor splice variants MOR-1D, MOR-1 and MOR-1C in the mouse and rat CNS. Neuroscience. 100: 141-53. PMID 10996465 DOI: 10.1016/S0306-4522(00)00248-7  0.38
2000 Silva RM, Rossi GC, Mathis JP, Standifer KM, Pasternak GW, Bodnar RJ. Morphine and morphine-6beta-glucuronide-induced feeding are differentially reduced by G-protein alpha-subunit antisense probes in rats. Brain Research. 876: 62-75. PMID 10973594 DOI: 10.1016/S0006-8993(00)02621-4  0.498
2000 Abbadie C, Gultekin SH, Pasternak GW. Immunohistochemical localization of the carboxy terminus of the novel mu opioid receptor splice variant MOR-1C within the human spinal cord. Neuroreport. 11: 1953-7. PMID 10884050  0.386
2000 Letchworth SR, Mathis JP, Rossi GC, Bodnar RJ, Pasternak GW. Autoradiographic localization of (125)I[Tyr(14)]orphanin FQ/nociceptin and (125)I[Tyr(10)]orphanin FQ/nociceptin(1-11) binding sites in rat brain. The Journal of Comparative Neurology. 423: 319-29. PMID 10867661 DOI: 10.1002/1096-9861(20000724)423:2<319::Aid-Cne9>3.0.Co;2-C  0.353
2000 Stein JA, Znamensky V, Baumer F, Rossi GC, Pasternak GW, Bodnar RJ. Mercaptoacetate induces feeding through central opioid-mediated mechanisms in rats. Brain Research. 864: 240-51. PMID 10802031 DOI: 10.1016/S0006-8993(00)02162-4  0.647
2000 Abbadie C, Pan YX, Pasternak GW. Differential distribution in rat brain of mu opioid receptor carboxy terminal splice variants MOR-1C-like and MOR-1-like immunoreactivity: Evidence for region-specific processing Journal of Comparative Neurology. 419: 244-256. PMID 10723002 DOI: 10.1002/(Sici)1096-9861(20000403)419:2<244::Aid-Cne8>3.0.Co;2-R  0.443
2000 Pan YX, Xu J, Bolan E, Chang A, Mahurter L, Rossi G, Pasternak GW. Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR-1F Febs Letters. 466: 337-340. PMID 10682855 DOI: 10.1016/S0014-5793(00)01095-4  0.86
1999 Zhu Y, King MA, Schuller AG, Nitsche JF, Reidl M, Elde RP, Unterwald E, Pasternak GW, Pintar JE. Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice. Neuron. 24: 243-52. PMID 10677041 DOI: 10.1016/S0896-6273(00)80836-3  0.595
1999 Walker JR, King M, Izzo E, Koob GF, Pasternak GW. Antagonism of heroin and morphine self-administration in rats by the morphine-6β-glucuronide antagonist 3-O-methylnaltrexone European Journal of Pharmacology. 383: 115-119. PMID 10585524 DOI: 10.1016/S0014-2999(99)00633-0  0.535
1999 Pasternak GW, Pan YX. Antisense mapping: Assessing functional significance of genes and splice variants Methods in Enzymology. 314: 51-60. PMID 10565004 DOI: 10.1016/S0076-6879(99)14094-1  0.321
1999 Zuckerman A, Bolan E, De Paulis T, Schmidt D, Spector S, Pasternak GW. Pharmacological characterization of morphine-6-sulfate and codeine-6- sulfate Brain Research. 842: 1-5. PMID 10526089 DOI: 10.1016/S0006-8993(99)01766-7  0.815
1999 Hom JS, Goldberg I, Mathis J, Pan YX, Brooks AI, Ryan-Moro J, Scheinberg DA, Pasternak GW. [(125)I]orphanin FQ/nociceptin binding in Raji cells. Synapse (New York, N.Y.). 34: 187-91. PMID 10523756 DOI: 10.1002/(Sici)1098-2396(19991201)34:3<187::Aid-Syn3>3.0.Co;2-A  0.417
1999 Mathis JP, Goldberg IE, Letchworth SR, Ryan-Moro JP, Pasternak GW. Identification of a high-affinity orphanin FQ/nociceptin(1-11) binding site in mouse brain. Synapse (New York, N.Y.). 34: 181-6. PMID 10523755 DOI: 10.1002/(Sici)1098-2396(19991201)34:3<181::Aid-Syn2>3.0.Co;2-V  0.525
1999 Kolesnikov YA, Pasternak GW. Peripheral blockade of topical morphine tolerance by ketamine European Journal of Pharmacology. 374: R1-R2. PMID 10422774 DOI: 10.1016/S0014-2999(99)00318-0  0.572
1999 Pan YX, Xu J, Bolan E, Abbadie C, Chang A, Zuckerman A, Rossi G, Pasternak GW. Identification and characterization of three new alternatively spliced μ-opioid receptor isoforms Molecular Pharmacology. 56: 396-403. PMID 10419560 DOI: 10.1124/Mol.56.2.396  0.868
1999 Kolesnikov Y, Pasternak GW. Topical opioids in mice: Analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist Journal of Pharmacology and Experimental Therapeutics. 290: 247-252. PMID 10381783  0.53
1999 Kolesnikov YA, Pasternak GW. Peripheral orphanin FQ/Nociceptin analgesia in the mouse Life Sciences. 64: 2021-2028. PMID 10374927 DOI: 10.1016/S0024-3205(99)00149-6  0.527
1999 Pasternak KR, Rossi GC, Zuckerman A, Pasternak GW. Antisense mapping KOR-1: Evidence for multiple kappa analgesic mechanisms Brain Research. 826: 289-292. PMID 10224306 DOI: 10.1016/S0006-8993(99)01294-9  0.402
1999 Schuller AG, King MA, Zhang J, Bolan E, Pan YX, Morgan DJ, Chang A, Czick ME, Unterwald EM, Pasternak GW, Pintar JE. Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1. Nature Neuroscience. 2: 151-6. PMID 10195199 DOI: 10.1038/5706  0.863
1998 King M, Chang A, Pasternak GW. Functional blockade of opioid analgesia by orphanin FQ/nociceptin Biochemical Pharmacology. 55: 1537-1540. PMID 10076548 DOI: 10.1016/S0006-2952(98)00023-9  0.621
1998 Leventhal L, Silva RM, Rossi GC, Pasternak GW, Bodnar RJ. Morphine-6beta-glucuronide-induced hyperphagia: characterization of opioid action by selective antagonists and antisense mapping in rats. The Journal of Pharmacology and Experimental Therapeutics. 287: 538-44. PMID 9808678  0.536
1998 Pan YX, Xu J, Wan BL, Zuckerman A, Pasternak GW. Identification and differential regional expression of KOR-3/ORL-1 gene splice variants in mouse brain Febs Letters. 435: 65-68. PMID 9755860 DOI: 10.1016/S0014-5793(98)01039-4  0.403
1998 Mathis JP, Goldberg IE, Rossi GC, Leventhal L, Pasternak GW. Antinociceptive analogs of orphanin FQ/nociceptin(1-11). Life Sciences. 63: PL 161-6. PMID 9747901 DOI: 10.1016/S0024-3205(98)00358-0  0.448
1998 Pasternak GW. The central questions in pain perception may be peripheral Proceedings of the National Academy of Sciences of the United States of America. 95: 10354-10355. PMID 9724706 DOI: 10.1073/Pnas.95.18.10354  0.454
1998 Goldberg IE, Rossi GC, Letchworth SR, Mathis JP, Ryan-Moro J, Leventhal L, Su W, Emmel D, Bolan EA, Pasternak GW. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 286: 1007-13. PMID 9694962  0.855
1998 Chang A, Emmel DW, Rossi GC, Pasternak GW. Methadone analgesia in morphine-insensitive CXBK mice European Journal of Pharmacology. 351: 189-191. PMID 9687002 DOI: 10.1016/S0014-2999(98)00366-5  0.693
1998 Krzanowska EK, Rossi GC, Pasternak GW, Bodnar RJ. Potency ratios of morphine and morphine-6beta-glucuronide analgesia elicited from the periaqueductal gray, locus coeruleus or rostral ventromedial medulla of rats. Brain Research. 799: 329-33. PMID 9675330 DOI: 10.1016/S0006-8993(98)00520-4  0.53
1998 Leventhal L, Mathis JP, Rossi GC, Pasternak GW, Bodnar RJ. Orphan opioid receptor antisense probes block orphanin FQ-induced hyperphagia. European Journal of Pharmacology. 349: R1-3. PMID 9669488 DOI: 10.1016/S0014-2999(98)00272-6  0.645
1998 Brown GP, Pasternak GW. 3H-Naloxone benzoylhydrazone binding in MOR-1-transfected Chinese hamster ovary cells: Evidence for G-protein-dependent antagonist binding Journal of Pharmacology and Experimental Therapeutics. 286: 376-381. PMID 9655882  0.437
1998 Burdick K, Yu WZ, Ragnauth A, Moroz M, Pan YX, Rossi GC, Pasternak GW, Bodnar RJ. Antisense mapping of opioid receptor clones: effects upon 2-deoxy-D-glucose-induced hyperphagia. Brain Research. 794: 359-63. PMID 9622675 DOI: 10.1016/S0006-8993(98)00331-X  0.513
1998 Pan YX, Mei J, Xu J, Wan BL, Zuckerman A, Pasternak GW. Cloning and characterization of a mouse σ1 receptor Journal of Neurochemistry. 70: 2279-2285. PMID 9603192 DOI: 10.1046/J.1471-4159.1998.70062279.X  0.438
1998 Rossi GC, Mathis JP, Pasternak GW. Analgesic activity of orphanin FQ2, murine prepro-orphanin FQ141-157 in mice. Neuroreport. 9: 1165-8. PMID 9601687  0.5
1998 Rossi GC, Perlmutter M, Leventhal L, Talatti A, Pasternak GW. Orphanin FQ/nociceptin analgesia in the rat Brain Research. 792: 327-330. PMID 9593974 DOI: 10.1016/S0006-8993(97)01490-X  0.615
1998 Kolesnikov Y, Jain S, Wilson R, Pasternak GW. Lack of morphine and enkephalin tolerance in 129/SvEv mice: Evidence for a NMDA receptor defect Journal of Pharmacology and Experimental Therapeutics. 284: 455-459. PMID 9454784  0.399
1998 Charton M, Ciszewska GR, Ginos J, Standifer KM, Brooks AI, Brown GP, Ryan-Moro JP, Pasternak GW. Quantitative structure activity relationships for substituted naloxone benzoylhlydrazones. 4'-substituted naloxone benzoylhydrazones Quantitative Structure-Activity Relationships. 17: 109-121. DOI: 10.1002/(Sici)1521-3838(199804)17:02<109::Aid-Qsar109>3.3.Co;2-T  0.387
1998 Charton M, Ciszewska GR, Ginos J, Standifer KM, Brooks AI, Brown GP, Ryan-Moro JP, Pasternak GW. Quantitative Structure Activity Relationships for Substituted Naloxone Benzoylhydrazones. 4′-substituted Naloxone Benzoylhydrazones: QSAR for 4′-substituted Naloxone Benzoylhydrazones Quantitative Structure-Activity Relationships. 17: 109-121. DOI: 10.1002/(Sici)1521-3838(199804)17:02<109::Aid-Qsar109>3.0.Co;2-1  0.414
1997 Leventhal L, Stevens LB, Rossi GC, Pasternak GW, Bodnar RJ. Antisense mapping of the MOR-1 opioid receptor clone: modulation of hyperphagia induced by DAMGO. The Journal of Pharmacology and Experimental Therapeutics. 282: 1402-7. PMID 9316853  0.565
1997 Brown GP, Yang K, Ouerfelli O, Standifer KM, Byrd D, Pasternak GW. 3H-morphine-6β-glucuronide binding in brain membranes and an MOR-1- transfected cell line Journal of Pharmacology and Experimental Therapeutics. 282: 1291-1297. PMID 9316837  0.46
1997 King M, Pan YX, Mei J, Chang A, Xu J, Pasternak GW. Enhanced κ-opioid receptor-mediated analgesia by antisense targeting the σ1 receptor European Journal of Pharmacology. 331: R5-R6. PMID 9274937 DOI: 10.1016/S0014-2999(97)01064-9  0.661
1997 Rossi GC, Leventhal L, Bolan E, Pasternak GW. Pharmacological characterization of orphanin FQ/nociceptin and its fragments Journal of Pharmacology and Experimental Therapeutics. 282: 858-865. PMID 9262352  0.848
1997 Brown GP, Yang K, King MA, Rossi GC, Leventhal L, Chang A, Pasternak GW. 3-Methoxynaltrexone, a selective heroin/morphine-6β-glucuronide antagonist Febs Letters. 412: 35-38. PMID 9257684 DOI: 10.1016/S0014-5793(97)00710-2  0.617
1997 Kolesnikov YA, Pan YX, Babey AM, Jain S, Wilson R, Pasternak GW. Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance Proceedings of the National Academy of Sciences of the United States of America. 94: 8220-8225. PMID 9223342 DOI: 10.1073/Pnas.94.15.8220  0.546
1997 Standifer KM, Pasternak GW. G proteins and opioid receptor-mediated signalling Cellular Signalling. 9: 237-248. PMID 9218123 DOI: 10.1016/S0898-6568(96)00174-X  0.628
1997 Rossi GC, Su W, Leventhal L, Su H, Pasternak GW. Antisense mapping DOR-1 in mice: Further support for δ receptor subtypes Brain Research. 753: 176-179. PMID 9125445 DOI: 10.1016/S0006-8993(97)00081-4  0.514
1997 Rossi GC, Leventhal L, Pan YX, Cole J, Su W, Bodnar RJ, Pasternak GW. Antisense mapping of MOR-1 in rats: distinguishing between morphine and morphine-6beta-glucuronide antinociception. The Journal of Pharmacology and Experimental Therapeutics. 281: 109-14. PMID 9103486  0.506
1997 King MA, Rossi GC, Chang AH, Williams L, Pasternak GW. Spinal analgesic activity of orphanin FQ/nociceptin and its fragments Neuroscience Letters. 223: 113-116. PMID 9089686 DOI: 10.1016/S0304-3940(97)13414-0  0.363
1997 Chien CC, Carroll FI, Brown GP, Pan YX, Bowen W, Pasternak GW. Synthesis and characterization of [125I]3'-(-)-iodopentazocine, a selective sigma 1 receptor ligand. European Journal of Pharmacology. 321: 361-8. PMID 9085049 DOI: 10.1016/S0014-2999(96)00963-6  0.592
1997 Kolesnikov Y, Jain S, Wilson R, Pasternak GW. Blockade of morphine-induced hindlimb myoclonic seizures in mice by ketamine Pharmacology Biochemistry and Behavior. 56: 423-425. PMID 9077578 DOI: 10.1016/S0091-3057(96)00221-3  0.496
1997 Mathis JP, Ryan-Moro J, Chang A, Hom JS, Scheinberg DA, Pasternak GW. Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain. Biochemical and Biophysical Research Communications. 230: 462-5. PMID 9016803 DOI: 10.1006/Bbrc.1996.5867  0.567
1996 Brooks AI, Standifer KM, Rossi GC, Mathis JP, Pasternak GW. Characterizing kappa3 opioid receptors with a selective monoclonal antibody. Synapse (New York, N.Y.). 22: 247-52. PMID 9132993 DOI: 10.1002/(Sici)1098-2396(199603)22:3<247::Aid-Syn7>3.0.Co;2-C  0.622
1996 Ryan-Moro J, Chien CC, Standifer KM, Pasternak GW. Sigma1 binding in a human neuroblastoma cell line Neurochemical Research. 21: 1309-1314. PMID 8947921 DOI: 10.1007/Bf02532372  0.548
1996 Kolesnikov YA, Jain S, Wilson R, Pasternak GW. Peripheral morphine analgesia: Synergy with central sites and a target of morphine tolerance Journal of Pharmacology and Experimental Therapeutics. 279: 502-506. PMID 8930151  0.527
1996 Pan YX, Xu J, Ryan-Moro J, Mathis J, Hom JS, Mei J, Pasternak GW. Dissociation of affinity and efficacy in KOR-3 chimeras. Febs Letters. 395: 207-10. PMID 8898097 DOI: 10.1016/0014-5793(96)01023-X  0.505
1996 Rossi GC, Brown GP, Leventhal L, Yang K, Pasternak GW. Novel receptor mechanisms for heroin and morphine-6β-glucuronide analgesia Neuroscience Letters. 216: 1-4. PMID 8892377 DOI: 10.1016/0304-3940(96)12976-1  0.64
1996 Rossi GC, Leventhal L, Pasternak GW. Naloxone sensitive orphanin FQ-induced analgesia in mice European Journal of Pharmacology. 311: R7-R8. PMID 8891615 DOI: 10.1016/0014-2999(96)00578-X  0.696
1996 Ciszewska GR, Ginos JA, Charton M, Standifer KM, Brooks AI, Brown GP, Ryan-Moro JP, Berzetei-Gurske I, Toll L, Pasternak GW. Synthesis and characterization of substituted benzoylhydrazones of naloxone. Synapse (New York, N.Y.). 24: 193-201. PMID 8890461 DOI: 10.1002/(Sici)1098-2396(199610)24:2<193::Aid-Syn11>3.0.Co;2-#  0.537
1996 Kolesnikov Y, Jain S, Wilson R, Pasternak GW. Peripheral κ1-opioid receptor-mediated analgesia in mice European Journal of Pharmacology. 310: 141-143. PMID 8884210 DOI: 10.1016/0014-2999(96)00520-1  0.612
1996 Leventhal L, Cole JL, Rossi GC, Pan YX, Pasternak GW, Bodnar RJ. Antisense oligodeoxynucleotides against the MOR-1 clone alter weight and ingestive responses in rats. Brain Research. 719: 78-84. PMID 8782866 DOI: 10.1016/0006-8993(96)00089-3  0.528
1996 Kolesnikov Y, Jain S, Pasternak GW. Modulation of opioid analgesia by agmatine European Journal of Pharmacology. 296: 17-22. PMID 8720472 DOI: 10.1016/0014-2999(95)00669-9  0.666
1996 Standifer KM, Rossi GC, Pasternak GW. Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein α subunits Molecular Pharmacology. 50: 293-298. PMID 8700136  0.398
1996 Pan YX, Xu J, Pasternak GW. Structure and characterization of the gene encoding a mouse kappa3-related opioid receptor Gene. 171: 255-260. PMID 8666282 DOI: 10.1016/0378-1119(95)00890-X  0.473
1996 Pasternak GW, Standifer KM. Pasternak and Standifer reply Trends in Pharmacological Sciences. 17: 217-218. DOI: 10.1016/0165-6147(96)81602-6  0.584
1996 Khanolkar AD, Yin D, Makriyannis A, Brooks AI, Pasternak GW, Froimowitz M. The morphine-like and nonmorphine-like conformers of prodine opioids Medicinal Chemistry Research. 6: 11-21.  0.583
1995 Chien CC, Pasternak GW. (-)-Pentazocine analgesia in mice: interactions with a σ receptor system European Journal of Pharmacology. 294: 303-308. PMID 8788445 DOI: 10.1016/0014-2999(95)00552-8  0.627
1995 Pasternak GW, Kolesnikov YA, Babey AM. Perspectives on the N-methyl-D-aspartate/nitric oxide cascade and opioid tolerance Neuropsychopharmacology. 13: 309-313. PMID 8747755 DOI: 10.1016/0893-133X(95)00084-Q  0.583
1995 Pasternak GW. Nitric oxide and opioid tolerance Nida Research Monograph. 147: 182-194. PMID 8742787 DOI: 10.1016/0028-3908(94)90050-7  0.504
1995 Rossi GC, Standifer KM, Pasternak GW. Differential blockade of morphine and morphine-6β-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein α subunits in rats Neuroscience Letters. 198: 99-102. PMID 8592651 DOI: 10.1016/0304-3940(95)11977-5  0.603
1995 Cheng J, Standifer KM, Tublin PR, Su W, Pasternak GW. Demonstration of κ3-opioid receptors in the SH-SY5Y human neuroblastoma cell line Journal of Neurochemistry. 65: 170-175. PMID 7790858 DOI: 10.1046/J.1471-4159.1995.65010170.X  0.645
1995 Rossi GC, Pan YX, Brown GP, Pasternak GW. Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6β-glucuronide receptor Febs Letters. 369: 192-196. PMID 7649256 DOI: 10.1016/0014-5793(95)00757-Z  0.682
1995 Chien CC, Pasternak GW. Sigma antagonists potentiate opioid analgesia in rats Neuroscience Letters. 190: 137-139. PMID 7644123 DOI: 10.1016/0304-3940(95)11504-P  0.695
1995 Cole JL, Leventhal L, Pasternak GW, Bowen WD, Bodnar RJ. Reductions in body weight following chronic central opioid receptor subtype antagonists during development of dietary obesity in rats. Brain Research. 678: 168-76. PMID 7620885 DOI: 10.1016/0006-8993(95)00181-O  0.477
1995 Pasternak GW, Pan YX, Cheng J. Correlating the pharmacology and molecular biology of opioid receptors. Cloning and antisense mapping a kappa3-related opiate receptor Annals of the New York Academy of Sciences. 757: 332-338. PMID 7611690 DOI: 10.1111/j.1749-6632.1995.tb17491.x  0.456
1995 Pan YX, Cheng J, Xu J, Rossi G, Jacobson E, Ryan-Moro J, Brooks AI, Dean GE, Standifer KM, Pasternak GW. Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor. Molecular Pharmacology. 47: 1180-8. PMID 7603458  0.546
1995 Standifer KM, Jenab S, Su W, Chien CC, Pan YX, Inturrisi CE, Pasternak GW. Antisense oligodeoxynucleotides to the cloned δ receptor DOR-1: Uptake, stability, and regulation of gene expression Journal of Neurochemistry. 65: 1981-1987. PMID 7595481 DOI: 10.1046/J.1471-4159.1995.65051981.X  0.59
1995 Berzetei-Gurske IP, White A, Polgar W, DeCosta BR, Pasternak GW, Toll L. The in vitro pharmacological characterization of naloxone benzoylhydrazone European Journal of Pharmacology. 277: 257-263. PMID 7493617 DOI: 10.1016/0014-2999(95)00088-3  0.681
1995 Pasternak GW, Standifer KM. Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology Trends in Pharmacological Sciences. 16: 344-350. PMID 7491712 DOI: 10.1016/S0165-6147(00)89068-9  0.663
1995 Pasternak GW, Inturrisi CE. Section review central & peripheral nervous systems: Pharmacological modulation of opioid tolerance Expert Opinion On Investigational Drugs. 4: 271-281. DOI: 10.1517/13543784.4.4.271  0.577
1994 Tiseo PJ, Cheng J, Pasternak GW, Inturrisi CE. Modulation of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist LY274614: Assessment of opioid receptor changes Journal of Pharmacology and Experimental Therapeutics. 268: 195-201. PMID 8301558  0.591
1994 Chien CC, Brown G, Pan YX, Pasternak GW. Blockade of U50,488H analgesia by antisense oligodeoxynucleotides to a κ-opioid receptor European Journal of Pharmacology. 253: R7-R8. PMID 8200413 DOI: 10.1016/0014-2999(94)90209-7  0.676
1994 Rossi G, Pan YX, Cheng J, Pasternak GW. Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor Life Sciences. 54: PL375-PL379. PMID 8196473 DOI: 10.1016/0024-3205(94)90038-8  0.663
1994 Standifer KM, Chien CC, Wahlestedt C, Brown GP, Pasternak GW. Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor. Neuron. 12: 805-10. PMID 8161452 DOI: 10.1016/0896-6273(94)90333-6  0.662
1994 Katz Y, Weizman A, Pick CG, Pasternak GW, Liu L, Fonia O, Gavish M. Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity. Brain Research. 646: 235-41. PMID 8069669 DOI: 10.1016/0006-8993(94)90084-1  0.636
1994 Brooks AI, Standifer KM, Cheng J, Ciszewska G, Pasternak GW. Opioid binding in giant toad and goldfish brain. Receptor. 4: 55-62. PMID 8038707  0.429
1994 Bilsky EJ, Bernstein RN, Pasternak GW, Hruby VJ, Patel D, Porreca F, Lai J. Selective inhibition of [D-ALA2, GLU4]deltrophin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor Life Sciences. 55: PL37-PL43. PMID 8015351 DOI: 10.1016/0024-3205(94)90110-4  0.428
1994 Chien CC, Pasternak GW. Selective antagonism of opioid analgesia by a sigma system Journal of Pharmacology and Experimental Therapeutics. 271: 1583-1590. PMID 7996472  0.624
1994 Kolesnikov YA, Maccechini ML, Pasternak GW. 1-aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance Life Sciences. 55: 1393-1398. PMID 7934650 DOI: 10.1016/0024-3205(94)00753-5  0.659
1994 Standifer KM, Cheng J, Brooks AI, Honrado CP, Su W, Visconti LM, Biedler JL, Pasternak GW. Biochemical and pharmacological characterization of mu, delta and kappa 3 opioid receptors expressed in BE(2)-C neuroblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 270: 1246-55. PMID 7932177  0.567
1994 Visconti LM, Standifer KM, Schiller PW, Pasternak GW. TIPP[ψ], a highly selective δ ligand Neuroscience Letters. 181: 47-49. PMID 7898768 DOI: 10.1016/0304-3940(94)90557-6  0.467
1994 Rossi GC, Pasternak GW, Bodnar RJ. Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla. Brain Research. 665: 85-93. PMID 7882023 DOI: 10.1016/0006-8993(94)91155-X  0.598
1994 Dooley CT, Chung NN, Wilkes BC, Schiller PW, Bidlack JM, Pasternak GW, Houghten RA. An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library. Science (New York, N.Y.). 266: 2019-22. PMID 7801131 DOI: 10.1126/Science.7801131  0.545
1994 Uhl GR, Childers S, Pasternak G. An opiate-receptor gene family reunion. Trends in Neurosciences. 17: 89-93. PMID 7515530 DOI: 10.1016/0166-2236(94)90110-4  0.38
1994 Elliott K, Minami N, Kolesnikov YA, Pasternak GW, Inturrisi CE. The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids Pain. 56: 69-75. PMID 7512709 DOI: 10.1016/0304-3959(94)90151-1  0.645
1994 Pasternak G. Anti-opioid activity of sigma1 systems Regulatory Peptides. 54: 219-220. DOI: 10.1016/0167-0115(94)90469-3  0.562
1994 Pan Y, Cheng J, Xu J, Pasternak G. Cloning, expression and classification of a kappa3-related opioid receptor using antisense oligodeoxynucleotides☆ Regulatory Peptides. 54: 217-218. DOI: 10.1016/0167-0115(94)90468-5  0.546
1994 Lai J, Bilsky EJ, Bernstein RN, Rothman RB, Pasternak GW, Porreca F. Antisense oligodeoxynucleotide to the cloned delta opioid receptor selectively inhibits supraspinal, but not spinal, antinociceptive effects of [D-Ala2, Glu4]deltorphin Regulatory Peptides. 54: 159-160. DOI: 10.1016/0167-0115(94)90439-1  0.59
1994 Lipkowski AW, Pasternak GW, Misterek K, Gumulka SW, Pachocka M. Synthesis and biological properties of new naltrexone-peptide hybrids Regulatory Peptides. 53: S127-S128. DOI: 10.1016/0167-0115(94)90274-7  0.554
1993 Negus SS, Pasternak GW, Koob GF, Weinger MB. Antagonist effects of beta-funaltrexamine and naloxonazine on alfentanil-induced antinociception and muscle rigidity in the rat. The Journal of Pharmacology and Experimental Therapeutics. 264: 739-45. PMID 8437122  0.5
1993 Kolesnikov YA, Ferkany J, Pasternak GW. Blockade of mu and kappa 1 opioid analgesic tolerance by NPC17742, a novel NMDA antagonist. Life Sciences. 53: 1489-94. PMID 8412512 DOI: 10.1016/0024-3205(93)90622-A  0.562
1993 Rossi GC, Pasternak GW, Bodnar RJ. Synergistic brainstem interactions for morphine analgesia. Brain Research. 624: 171-80. PMID 8252389 DOI: 10.1016/0006-8993(93)90075-X  0.609
1993 Chien CC, Pasternak GW. Functional antagonism of morphine analgesia by (+)-pentazocine: evidence for an anti-opioid σ1 system European Journal of Pharmacology. 250: R7-R8. PMID 8119306 DOI: 10.1016/0014-2999(93)90650-7  0.667
1993 Pasternak GW. Pharmacological mechanisms of opioid analgesics. Clinical Neuropharmacology. 16: 1-18. PMID 8093680 DOI: 10.1097/00002826-199302000-00001  0.616
1993 Kolesnikov YA, Pick CG, Ciszewska G, Pasternak GW. Blockade of tolerance to morphine but not to κ opioids by a nitric oxide synthase inhibitor Proceedings of the National Academy of Sciences of the United States of America. 90: 5162-5166. PMID 7685116 DOI: 10.1073/Pnas.90.11.5162  0.523
1992 Kinouchi K, Brown G, Pasternak G, Donner DB. Identification and characterization of receptors for tumor necrosis factor-alpha in the brain. Biochemical and Biophysical Research Communications. 181: 1532-8. PMID 1662500 DOI: 10.1016/0006-291X(91)92113-X  0.368
1992 Kolesnikov YA, Pick CG, Pasternak GW. NG-nitro-L-arginine prevents morphine tolerance. European Journal of Pharmacology. 221: 399-400. PMID 1426018 DOI: 10.1016/0014-2999(92)90732-J  0.521
1992 Galer BS, Coyle N, Pasternak GW, Portenoy RK. Individual variability in the response to different opioids: report of five cases. Pain. 49: 87-91. PMID 1375728 DOI: 10.1016/0304-3959(92)90192-E  0.592
1992 Tive L, Ginsberg K, Pick CG, Pasternak GW. Kappa 3 receptors and levorphanol-induced analgesia. Neuropharmacology. 31: 851-6. PMID 1331842 DOI: 10.1016/0028-3908(92)90121-5  0.637
1992 Pick CG, Roques B, Gacel G, Pasternak GW. Supraspinal mu 2-opioid receptors mediate spinal/supraspinal morphine synergy. European Journal of Pharmacology. 220: 275-7. PMID 1330618 DOI: 10.1016/0014-2999(92)90761-R  0.636
1992 Cheng J, Roques BP, Gacel GA, Huang E, Pasternak GW. Kappa 3 opiate receptor binding in the mouse and rat. European Journal of Pharmacology. 226: 15-20. PMID 1327838 DOI: 10.1016/0922-4106(92)90077-9  0.486
1992 Tive LA, Pick CG, Paul D, Roques BP, Gacel GA, Pasternak GW. Analgesic potency of TRIMU-5: a mixed mu 2 opioid receptor agonist/mu 1 opioid receptor antagonist. European Journal of Pharmacology. 216: 249-55. PMID 1327812 DOI: 10.1016/0014-2999(92)90367-D  0.759
1992 Koch JE, Pasternak GW, Arjune D, Bodnar RJ. Naloxone benzoylhydrazone, a kappa 3 opioid agonist, stimulates food intake in rats. Brain Research. 581: 311-4. PMID 1327401 DOI: 10.1016/0006-8993(92)90723-M  0.557
1992 Pick CG, Paul D, Pasternak GW. Nalbuphine, a mixed kappa 1 and kappa 3 analgesic in mice. The Journal of Pharmacology and Experimental Therapeutics. 262: 1044-50. PMID 1326621  0.706
1992 Pick CG, Paul D, Eison MS, Pasternak GW. Potentiation of opioid analgesia by the antidepressant nefazodone. European Journal of Pharmacology. 211: 375-81. PMID 1319913 DOI: 10.1016/0014-2999(92)90395-K  0.694
1992 Froimowitz M, Pick CG, Pasternak GW. Phenylmorphans and analogues: opioid receptor subtype selectivity and effect of conformation on activity. Journal of Medicinal Chemistry. 35: 1521-5. PMID 1315868 DOI: 10.1021/Jm00087A004  0.673
1991 Pick CG, Paul D, Pasternak GW. Comparison of naloxonazine and beta-funaltrexamine antagonism of mu 1 and mu 2 opioid actions. Life Sciences. 48: 2005-11. PMID 1851915 DOI: 10.1016/0024-3205(91)90155-5  0.655
1991 Paul D, Pick CG, Tive LA, Pasternak GW. Pharmacological characterization of nalorphine, a kappa 3 analgesic. The Journal of Pharmacology and Experimental Therapeutics. 257: 1-7. PMID 1850462  0.706
1991 Liu L, Katz Y, Weizman R, Rosenberg B, Pasternak GW, Gavish M. Interactions of chloroquine with benzodiazepine, gamma-aminobutyric acid and opiate receptors. Biochemical Pharmacology. 41: 1534-6. PMID 1850280 DOI: 10.1016/0006-2952(91)90574-O  0.379
1991 Kinouchi K, Pasternak GW. Evidence for kappa 1 opioid receptor multiplicity in the guinea pig cerebellum. European Journal of Pharmacology. 207: 135-41. PMID 1679014 DOI: 10.1016/0922-4106(91)90088-Y  0.421
1991 Kepler KL, Standifer KM, Paul D, Kest B, Pasternak GW, Bodnar RJ. Gender effects and central opioid analgesia. Pain. 45: 87-94. PMID 1677751 DOI: 10.1016/0304-3959(91)90168-W  0.753
1991 Pick CG, Cheng J, Paul D, Pasternak GW. Genetic influences in opioid analgesic sensitivity in mice. Brain Research. 566: 295-8. PMID 1667610 DOI: 10.1016/0006-8993(91)91712-A  0.679
1991 Bodnar R, Paul D, Pasternak GW. Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus. Brain Research. 558: 224-30. PMID 1664270 DOI: 10.1016/0006-8993(91)90772-N  0.705
1991 Inturrisi CE, Cerbone DJ, Chen D, Yoburn BC, Pasternak GW, Portenoy RK, Foley KM. Species Dependent Accumulation of Morphine-6-Glucuronide (M-6-G) After Morphine (MOR) Administration The Clinical Journal of Pain. 7: 42. DOI: 10.1097/00002508-199103000-00012  0.514
1990 Bodnar RJ, Paul D, Rosenblum M, Liu L, Pasternak GW. Blockade of morphine analgesia by both pertussis and cholera toxins in the periaqueductal gray and locus coeruleus. Brain Research. 529: 324-8. PMID 2282501 DOI: 10.1016/0006-8993(90)90845-3  0.691
1990 Paul D, Levison JA, Howard DH, Pick CG, Hahn EF, Pasternak GW. Naloxone benzoylhydrazone (NalBzoH) analgesia. The Journal of Pharmacology and Experimental Therapeutics. 255: 769-74. PMID 2173757  0.733
1990 Kinouchi K, Standifer KM, Pasternak GW. Modulation of μ1, μ2, and δ opioid binding by divalent cations Biochemical Pharmacology. 40: 382-384. PMID 2165406 DOI: 10.1016/0006-2952(90)90704-O  0.58
1990 Bodnar RJ, Paul D, Pasternak GW. Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice. Neuropharmacology. 29: 507-10. PMID 2162497 DOI: 10.1016/0028-3908(90)90174-P  0.752
1990 Mann PE, Pasternak GW, Bridges RS. Mu 1 opioid receptor involvement in maternal behavior. Physiology & Behavior. 47: 133-8. PMID 2158113 DOI: 10.1016/0031-9384(90)90051-5  0.535
1990 Arjune D, Standifer KM, Pasternak GW, Bodnar RJ. Reduction by central beta-funaltrexamine of food intake in rats under freely-feeding, deprivation and glucoprivic conditions. Brain Research. 535: 101-9. PMID 1963340 DOI: 10.1016/0006-8993(90)91828-5  0.569
1989 Pasternak GW. Studies of multiple morphine and enkephalin receptors: evidence for mu1 receptors. Advances in Experimental Medicine and Biology. 236: 81-93. PMID 2853569 DOI: 10.1007/978-1-4757-5971-6_7  0.487
1989 Adler BA, Goodman RR, Pasternak GW. Quantitative autoradiographic distribution of meptazinol-sensitive binding sites in rat brain. Cellular and Molecular Neurobiology. 8: 471-6. PMID 2852061 DOI: 10.1007/Bf00711230  0.504
1989 Paul D, Standifer KM, Inturrisi CE, Pasternak GW. Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. The Journal of Pharmacology and Experimental Therapeutics. 251: 477-83. PMID 2810109  0.669
1989 Bodnar RJ, Pasternak GW, Mann PE, Paul D, Warren R, Donner DB. Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat. Cancer Research. 49: 6280-4. PMID 2804974  0.449
1989 Ling GS, Paul D, Simantov R, Pasternak GW. Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model. Life Sciences. 45: 1627-36. PMID 2555641 DOI: 10.1016/0024-3205(89)90272-5  0.674
1989 Paul D, Bodnar RJ, Gistrak MA, Pasternak GW. Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice. European Journal of Pharmacology. 168: 307-14. PMID 2555205 DOI: 10.1016/0014-2999(89)90792-9  0.679
1989 Gistrak MA, Paul D, Hahn EF, Pasternak GW. Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone. The Journal of Pharmacology and Experimental Therapeutics. 251: 469-76. PMID 2553921  0.703
1988 Mann PE, Pasternak GW, Hahn EF, Curreri G, Lubin E, Bodnar RJ. Comparison of effects of chronic administration of naloxone and naloxonazine upon food intake and maintainance of body weight in rats. Neuropharmacology. 27: 349-55. PMID 3419536 DOI: 10.1016/0028-3908(88)90142-6  0.499
1988 Mann PE, Arjune D, Romero MT, Pasternak GW, Hahn EF, Bodnar RJ. Differential sensitivity of opioid-induced feeding to naloxone and naloxonazine. Psychopharmacology. 94: 336-41. PMID 2895939 DOI: 10.1007/Bf00174686  0.631
1988 Bodnar RJ, Clark JA, Cooper ML, Pasternak GW. Loss of striatal mu1 opiate binding by substantia nigra lesions in the rat. Life Sciences. 43: 1697-700. PMID 2848168 DOI: 10.1016/0024-3205(88)90480-8  0.462
1988 Yoburn BC, Luke MC, Pasternak GW, Inturrisi CE. Upregulation of opioid receptor subtypes correlates with potency changes of morphine and dadle Life Sciences. 43: 1319-1324. PMID 2845219 DOI: 10.1016/0024-3205(88)90587-5  0.674
1988 Luke MC, Hahn EF, Price M, Pasternak GW. Irreversible opiate agonists and antagonists: V. Hydrazone and acylhydrazone derivatives of naltrexone. Life Sciences. 43: 1249-56. PMID 2845215 DOI: 10.1016/0024-3205(88)90215-9  0.443
1988 Paul D, Pasternak GW. Differential blockade by naloxonazine of two mu opiate actions: analgesia and inhibition of gastrointestinal transit. European Journal of Pharmacology. 149: 403-4. PMID 2842168 DOI: 10.1016/0014-2999(88)90680-2  0.619
1988 Bodnar RJ, Williams CL, Lee SJ, Pasternak GW. Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study. Brain Research. 447: 25-34. PMID 2838129 DOI: 10.1016/0006-8993(88)90962-6  0.682
1988 Moulin DE, Ling GS, Pasternak GW. Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat. Pain. 33: 233-9. PMID 2837716 DOI: 10.1016/0304-3959(88)90095-4  0.677
1988 Clark JA, Pasternak GW. U50,488: a kappa-selective agent with poor affinity for mu1 opiate binding sites. Neuropharmacology. 27: 331-2. PMID 2836756 DOI: 10.1016/0028-3908(88)90052-4  0.556
1988 Pasternak GW. Multiple Morphine and Enkephalin Receptors and the Relief of Pain Jama: the Journal of the American Medical Association. 259: 1362. DOI: 10.1001/Jama.1988.03720090052035  0.508
1987 Urbanczyk-Lipkowska Z, Lipkowski AW, Etter MC, Hahn EF, Pasternak GW, Portoghese PS. X-ray crystal structure of the opioid ligand naltrexonazine. Journal of Medicinal Chemistry. 30: 1489-94. PMID 3039139 DOI: 10.1021/Jm00391A035  0.463
1987 Itzhak Y, Pasternak GW. Interaction of [D-Ser2,Leu5]enkephalin-Thr6 (DSLET), a relatively selective delta ligand, with MU1 opioid binding sites Life Sciences. 40: 307-311. PMID 3025547 DOI: 10.1016/0024-3205(87)90348-1  0.462
1987 Pasternak GW, Bodnar RJ, Clark JA, Inturrisi CE. Morphine-6-glucuronide, a potent mu agonist. Life Sciences. 41: 2845-9. PMID 2826951 DOI: 10.1016/0024-3205(87)90431-0  0.65
1987 Callahan P, Pasternak GW. Opiate receptor multiplicity: evidence for multiple mu receptors. Monographs in Neural Sciences. 13: 121-31. PMID 2825002 DOI: 10.1159/000414573  0.52
1987 Recht LD, Pasternak GW. Effects of beta-funaltrexamine on radiolabeled opioid binding. European Journal of Pharmacology. 140: 209-14. PMID 2822439 DOI: 10.1016/0014-2999(87)90807-7  0.416
1987 Galetta S, Hahn EF, Nishimura S, Pasternak GW. Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist. Life Sciences. 41: 783-7. PMID 2441221 DOI: 10.1016/0024-3205(87)90459-0  0.514
1986 Clark JA, Itzhak Y, Hruby VJ, Yamamura HI, Pasternak GW. [D-Pen2,D-Pen5]enkephalin (DPDPE): a delta-selective enkephalin with low affinity for mu 1 opiate binding sites. European Journal of Pharmacology. 128: 303-4. PMID 3025000 DOI: 10.1016/0014-2999(86)90784-3  0.55
1986 Ling GS, Simantov R, Clark JA, Pasternak GW. Naloxonazine actions in vivo. European Journal of Pharmacology. 129: 33-8. PMID 3021478 DOI: 10.1016/0014-2999(86)90333-X  0.601
1986 Simone DA, Bodnar RJ, Portzline T, Pasternak GW. Antagonism of morphine analgesia by intracerebroventricular naloxonazine. Pharmacology, Biochemistry, and Behavior. 24: 1721-7. PMID 3016762 DOI: 10.1016/0091-3057(86)90511-3  0.523
1986 Pasternak GW. Multiple morphine and enkephalin receptors: biochemical and pharmacological aspects. Annals of the New York Academy of Sciences. 467: 130-9. PMID 3014970 DOI: 10.1111/J.1749-6632.1986.Tb14624.X  0.649
1986 Itzhak Y, Pasternak GW. κ-Opiate binding to rat brain and guinea pig cerebellum: Sensitivity towards ions and nucleotides Neuroscience Letters. 64: 81-84. PMID 3008039 DOI: 10.1016/0304-3940(86)90667-1  0.337
1986 Pasternak GW. Multiple mu opiate receptors: biochemical and pharmacological evidence for multiplicity. Biochemical Pharmacology. 35: 361-4. PMID 3004499 DOI: 10.1016/0006-2952(86)90205-4  0.56
1986 Pasternak GW, Wood PJ. Multiple mu opiate receptors. Life Sciences. 38: 1889-98. PMID 2872563 DOI: 10.1016/0024-3205(86)90217-1  0.504
1986 LING GSF, SPIEGEL K, LOCKHART SH, PASTERNAK GW. Separation of Opioid Analgesia from Respiratory Depression Survey of Anesthesiology. 30: 57. DOI: 10.1097/00132586-198604000-00006  0.507
1985 Recht LD, Kent J, Pasternak GW. Quantitative autoradiography of the development of mu opiate binding sites in rat brain. Cellular and Molecular Neurobiology. 5: 223-9. PMID 2998624 DOI: 10.1007/Bf00711008  0.305
1985 Goodman RR, Adler BA, Pasternak GW. Regional differences in mu 1-binding of [3H][D-Ala2,D-Leu5]-enkephalin: comparisons of thalamus and cortex in the rat. Neuroscience Letters. 59: 155-8. PMID 2997666 DOI: 10.1016/0304-3940(85)90192-2  0.485
1985 Goodman RR, Pasternak GW. Visualization of mu1 opiate receptors in rat brain by using a computerized autoradiographic subtraction technique. Proceedings of the National Academy of Sciences of the United States of America. 82: 6667-71. PMID 2995978 DOI: 10.1073/pnas.82.19.6667  0.369
1985 Yoburn BC, Goodman RR, Cohen AH, Pasternak GW, Inturrisi CE. Increased analgesic potency of morphine and increased brain opioid binding sites in the rat following chronic naltrexone treatment. Life Sciences. 36: 2325-32. PMID 2989632 DOI: 10.1016/0024-3205(85)90322-4  0.564
1985 Simone DA, Bodnar RJ, Goldman EJ, Pasternak GW. Involvement of opioid receptor subtypes in rat feeding behavior. Life Sciences. 36: 829-33. PMID 2983173 DOI: 10.1016/0024-3205(85)90206-1  0.564
1984 Ling GS, MacLeod JM, Lee S, Lockhart SH, Pasternak GW. Separation of morphine analgesia from physical dependence. Science (New York, N.Y.). 226: 462-4. PMID 6541807 DOI: 10.1126/Science.6541807  0.598
1984 Pasternak GW, Gintzler AR, Houghten RA, Ling GS, Goodman RR, Spiegel K, Nishimura S, Johnson N, Recht LD. Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system. Life Sciences. 167-73. PMID 6319856 DOI: 10.1016/0024-3205(83)90470-8  0.554
1984 Ling GS, Galetta S, Pasternak GW. Oxymorphazone: a long-acting opiate analgesic. Cellular and Molecular Neurobiology. 4: 1-13. PMID 6204757 DOI: 10.1007/Bf00710938  0.487
1984 Johnson N, Itzhak Y, Pasternak GW. Interaction of two phencyclidine opiate-like derivatives with 3H-opioid binding sites European Journal of Pharmacology. 101: 281-284. PMID 6088255 DOI: 10.1016/0014-2999(84)90171-7  0.457
1984 Houghten R, Johnson N, Pasternak G. [3H]-beta-endorphin binding in rat brain The Journal of Neuroscience. 4: 2460-2465. DOI: 10.1523/Jneurosci.04-10-02460.1984  0.432
1983 Gintzler AR, Pasternak GW. Multiple mu receptors: evidence for mu2 sites in the guinea pig ileum. Neuroscience Letters. 39: 51-6. PMID 6314191 DOI: 10.1016/0304-3940(83)90164-7  0.658
1983 Wood PL, Pasternak GW. Specific mu 2 opioid isoreceptor regulation of nigrostriatal neurons: in vivo evidence with naloxonazine. Neuroscience Letters. 37: 291-3. PMID 6310456 DOI: 10.1016/0304-3940(83)90446-9  0.622
1983 Johnson N, Pasternak GW. The binding to rat brain homogenates of Mr2034, a universal opiate. Life Sciences. 33: 985-91. PMID 6310291 DOI: 10.1016/0024-3205(83)90755-5  0.407
1983 Ling GS, Pasternak GW. Spinal and supraspinal opioid analgesia in the mouse: the role of subpopulations of opioid binding sites. Brain Research. 271: 152-6. PMID 6309332 DOI: 10.1016/0006-8993(83)91376-8  0.659
1983 Holaday JW, Pasternak GW, Faden AI. Naloxazone pretreatment modifies cardiorespiratory, temperature, and behavioral effects of morphine. Neuroscience Letters. 37: 199-204. PMID 6308526 DOI: 10.1016/0304-3940(83)90153-2  0.633
1983 Holaday JW, Pasternak GW, D'Amato RJ, Ruvio BA, Faden AI. Naloxazone lacks therapeutic effects in endotoxic shock yet blocks the effects of naloxone. European Journal of Pharmacology. 89: 293-6. PMID 6307712 DOI: 10.1016/0014-2999(83)90509-5  0.591
1983 Ling GS, Spiegel K, Nishimura SL, Pasternak GW. Dissociation of morphine's analgesic and respiratory depressant actions. European Journal of Pharmacology. 86: 487-8. PMID 6299765 DOI: 10.1016/0014-2999(83)90203-0  0.434
1983 Spiegel K, Kourides IA, Pasternak GW. Different receptors mediate morphine-induced prolactin and growth hormone release. Life Sciences. 31: 2177-80. PMID 6298516 DOI: 10.1016/0024-3205(82)90112-6  0.466
1983 Burkhardt C, Frederickson RC, Pasternak GW. Metkephamid (Tyr-D-ala-Gly-Phe-N(Me)Met-NH2), a potent opioid peptide: receptor binding and analgesic properties. Peptides. 3: 869-71. PMID 6294639 DOI: 10.1016/0196-9781(82)90029-8  0.531
1983 Ling GS, Pasternak GW. Morphine catalepsy in the rat: involvement of mu 1 (high affinity) opioid binding sites. Neuroscience Letters. 32: 193-6. PMID 6292799 DOI: 10.1016/0304-3940(82)90273-7  0.611
1983 Hahn EF, Pasternak GW. Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites. Life Sciences. 31: 1385-8. PMID 6292633 DOI: 10.1016/0024-3205(82)90387-3  0.375
1983 Johnson N, Houghten R, Pasternak GW. Binding of 3H-beta-endorphin in rat brain. Life Sciences. 31: 1381-4. PMID 6292632 DOI: 10.1016/0024-3205(82)90386-1  0.324
1983 Pasternak GW. High and low affinity opioid binding sites: relationship to mu and delta sites. Life Sciences. 31: 1303-6. PMID 6292618 DOI: 10.1016/0024-3205(82)90367-8  0.534
1983 Galetta S, Ling GS, Wolfin L, Pasternak GW. Receptor binding and analgesic properties of oxymorphazone. Life Sciences. 31: 1389-92. PMID 6183551 DOI: 10.1016/0024-3205(82)90388-5  0.562
1983 Corrêa FM, Innis RB, Rouot B, Pasternak GW, Snyder SH. Fluorescent probes of alpha- and beta-adrenergic and opiate receptors: biochemical and histochemical evaluation. Neuroscience Letters. 16: 47-53. PMID 6133239 DOI: 10.1016/0304-3940(80)90099-3  0.571
1982 Kirchgessner AL, Bodnar RJ, Pasternak GW. Naloxazone and pain-inhibitory systems: evidence for a collateral inhibition model. Pharmacology, Biochemistry, and Behavior. 17: 1175-9. PMID 7163350 DOI: 10.1016/0091-3057(82)90116-2  0.606
1982 Nishimura S, Pasternak GW. Opiate and opioid peptide binding in rat goldfish: further evidence for opiate receptor heterogeneity. Brain Research. 248: 192-5. PMID 6289993 DOI: 10.1016/0006-8993(82)91164-7  0.591
1982 Pasternak GW. Opiate, enkephalin, and endorphin analgesia: relations to a single subpopulation of opiate receptors. Neurology. 31: 1311-5. PMID 6287349 DOI: 10.1212/WNL.31.10.1311  0.572
1982 Spiegel K, Kourides IA, Pasternak GW. Prolactin and growth hormone release by morphine in the rat: different receptor mechanisms. Science (New York, N.Y.). 217: 745-7. PMID 6285470 DOI: 10.1126/Science.6285470  0.502
1982 Zhang AZ, Pasternak GW. Ontogeny of opioid pharmacology and receptors: high and low affinity site differences. European Journal of Pharmacology. 73: 29-40. PMID 6274643 DOI: 10.1016/0014-2999(81)90142-4  0.443
1982 Zhang AZ, Pasternak GW. Opiates and enkephalins: a common binding site mediates their analgesic actions in rats. Life Sciences. 29: 843-51. PMID 6272049 DOI: 10.1016/0024-3205(81)90041-2  0.516
1982 Pasternak GW. Central mechanisms of opioid analgesia. Acupuncture & Electro-Therapeutics Research. 6: 135-49. PMID 6120618 DOI: 10.3727/036012981816952289  0.548
1982 Hahn E, Carroll-Buatti M, Pasternak G. Irreversible opiate agonists and antagonists: the 14- hydroxydihydromorphinone azines The Journal of Neuroscience. 2: 572-576. DOI: 10.1523/JNEUROSCI.02-05-00572.1982  0.502
1982 Childers SR, Pasternak GW. Naloxazone, a novel opiate antagonist: Irreversible blockade of rat brain opiate receptors in vitro Cellular and Molecular Neurobiology. 2: 93-103. DOI: 10.1007/Bf00711075  0.442
1981 Wolozin BL, Pasternak GW. Classification of multiple morphine and enkephalin binding sites in the central nervous system Proceedings of the National Academy of Sciences of the United States of America. 78: 6181-6185. PMID 6273857 DOI: 10.1073/Pnas.78.10.6181  0.431
1981 Buatti MC, Pasternak GW. Multiple opiate receptors: phylogenetic differences. Brain Research. 218: 400-5. PMID 6268247 DOI: 10.1016/0006-8993(81)91319-6  0.412
1981 Hazum E, Chang KJ, Cuatrecasas P, Pasternak GW. Naloxazone irreversibly inhibits the high affinity binding of [125I]D-ala2-D-leu5-enkephalin. Life Sciences. 28: 2973-9. PMID 6267402 DOI: 10.1016/0024-3205(81)90274-5  0.368
1981 Zhang AZ, Chang JK, Pasternak GW. The actions of naloxazone on the binding and analgesic properties of morphiceptin (NH2Tyr-Pro-Phe-Pro-CONH2), a selective mu-receptor ligand. Life Sciences. 28: 2829-36. PMID 6267398 DOI: 10.1016/0024-3205(81)90098-9  0.595
1981 Zhang AZ, Pasternak GW. mu- and delta-opiate receptors: correlation with high and low affinity opiate binding sites. European Journal of Pharmacology. 67: 323-4. PMID 6257533 DOI: 10.1016/0014-2999(80)90518-X  0.496
1981 PASTERNAK GW, CHILDERS SR, SNYDER SH, Brown BR. Opiate Analgesia Survey of Anesthesiology. 25: 214. DOI: 10.1097/00132586-198108000-00009  0.627
1981 Pasternak GW, Zhang A. Opiate and opioid peptide analgesia: A common receptor mechanism distinct from respiratory effects Pain. 11: S23. DOI: 10.1016/0304-3959(81)90232-3  0.604
1980 Pasternak GW, Zhang A, Tecott L. Developmental differences between high and low affinity opiate binding sites: their relationship to analgesia and respiratory depression. Life Sciences. 27: 1185-90. PMID 6252404 DOI: 10.1016/0024-3205(80)90470-1  0.368
1980 Pasternak GW. Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia. Proceedings of the National Academy of Sciences of the United States of America. 77: 3691-4. PMID 6251477 DOI: 10.1073/Pnas.77.6.3691  0.559
1980 Pasternak GW, Childers SR, Snyder SH. Opiate analgesia: Evidence for mediation by a subpopulation of opiate receptors Science. 208: 514-516. PMID 6245448 DOI: 10.1097/00132586-198108000-00009  0.576
1980 Pasternak GW. Endogenous opioid systems in brain. The American Journal of Medicine. 68: 157-9. PMID 6243856 DOI: 10.1016/0002-9343(80)90347-2  0.422
1980 Pasternak GW, Hahn EF. Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones. Journal of Medicinal Chemistry. 23: 674-6. PMID 6156240 DOI: 10.1002/Chin.198042277  0.553
1976 Pasternak GW, March SC, Parikh I, Snyder SH, Cuatrecasas P. Macromolecular naloxone: a novel long-acting polymer-bound drug. Life Sciences. 18: 977-81. PMID 1271967 DOI: 10.1016/0024-3205(76)90418-5  0.416
1976 Simantov R, Kuhar MJ, Pasternak GW, Snyder SH. The regional distribution of a morphine-like factors enkephalin in monkey brain. Brain Research. 106: 189-97. PMID 817783 DOI: 10.1016/0006-8993(76)90086-X  0.628
1975 Creese I, Pasternak GW, Pert CB, Snyder SH. Discrimination by temperature of opiate agonist and antagonist receptor binding. Life Sciences. 16: 1837-42. PMID 1152613 DOI: 10.1016/0024-3205(75)90287-8  0.791
1975 Pasternak GW, Goodman R, Snyder SH. An endogenous morphine-like factor in mammalian brain. Life Sciences. 16: 1765-9. PMID 1152600 DOI: 10.1016/0024-3205(75)90270-2  0.499
1975 Guarnieri M, Krell LS, McKhann GM, Pasternak GW, Yamamura HI. The effects of cell isolation techniques on neuronal membrane receptors. Brain Research. 93: 337-42. PMID 169956 DOI: 10.1016/0006-8993(75)90355-8  0.483
1973 Harik SI, Pasternak GW, Snyder SH. An enzymatic-isotopic microassay for putrescine. Biochimica Et Biophysica Acta. 304: 753-64. PMID 4580200 DOI: 10.1016/0304-4165(73)90222-5  0.517
1973 Pert CB, Pasternak G, Snyder SH. Opiate agonists and antagonists discriminated by receptor binding in brain. Science (New York, N.Y.). 182: 1359-61. PMID 4128222 DOI: 10.1126/science.182.4119.1359  0.762
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