David Nemazee - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Nemazee D, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/j.cell.2016.08.005  0.32
2016 Lai M, Gonzalez-Martin A, Cooper AB, Oda H, Jin HY, Shepherd J, He L, Zhu J, Nemazee D, Xiao C. Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs. Nature Communications. 7: 12207. PMID 27481093 DOI: 10.1038/ncomms12207  0.32
2015 Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Receptor editing and genetic variability in human autoreactive B cells. The Journal of Experimental Medicine. PMID 26694971 DOI: 10.1084/jem.20151039  0.32
2015 Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B, Menis S, Jones M, Kubitz M, Spencer S, Adachi Y, ... ... Nemazee D, et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science (New York, N.Y.). PMID 26089355 DOI: 10.1126/science.aac5894  0.32
2013 Doyle-Cooper C, Hudson KE, Cooper AB, Ota T, Skog P, Dawson PE, Zwick MB, Schief WR, Burton DR, Nemazee D. Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10. Journal of Immunology (Baltimore, Md. : 1950). 191: 3186-91. PMID 23940276 DOI: 10.4049/jimmunol.1301285  0.32
2013 Ota T, Doyle-Cooper C, Cooper AB, Doores KJ, Aoki-Ota M, Le K, Schief WR, Wyatt RT, Burton DR, Nemazee D. B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates. Journal of Immunology (Baltimore, Md. : 1950). 191: 3179-85. PMID 23940273 DOI: 10.4049/jimmunol.1301283  0.32
2013 Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, ... ... Nemazee D, et al. Rational HIV immunogen design to target specific germline B cell receptors. Science (New York, N.Y.). 340: 711-6. PMID 23539181 DOI: 10.1126/science.1234150  0.32
2013 Doores KJ, Huber M, Le KM, Wang SK, Doyle-Cooper C, Cooper A, Pantophlet R, Wong CH, Nemazee D, Burton DR. 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies. Journal of Virology. 87: 2234-41. PMID 23221565 DOI: 10.1128/JVI.02820-12  0.32
2012 Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, ... ... Nemazee D, et al. Anti-HIV B Cell lines as candidate vaccine biosensors. Journal of Immunology (Baltimore, Md. : 1950). 189: 4816-24. PMID 23066156 DOI: 10.4049/jimmunol.1202165  0.32
2012 Aoki-Ota M, Torkamani A, Ota T, Schork N, Nemazee D. Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. Journal of Immunology (Baltimore, Md. : 1950). 188: 2305-15. PMID 22287713 DOI: 10.4049/jimmunol.1103484  0.32
2011 Duong BH, Ota T, Aoki-Ota M, Cooper AB, Ait-Azzouzene D, Vela JL, Gavin AL, Nemazee D. Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape. Journal of Immunology (Baltimore, Md. : 1950). 187: 5596-605. PMID 22043016 DOI: 10.4049/jimmunol.1102479  0.32
2011 Siggs OM, Arnold CN, Huber C, Pirie E, Xia Y, Lin P, Nemazee D, Beutler B. The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nature Immunology. 12: 434-40. PMID 21423172 DOI: 10.1038/ni.2012  0.32
2011 Ota T, Ota M, Duong BH, Gavin AL, Nemazee D. Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing. The Journal of Experimental Medicine. 208: 617-29. PMID 21357741 DOI: 10.1084/jem.20102265  0.32
2011 Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 1993. 177: 1009-1020. Journal of Immunology (Baltimore, Md. : 1950). 186: 1313-24. PMID 21248269  0.32
2010 Ota M, Duong BH, Torkamani A, Doyle CM, Gavin AL, Ota T, Nemazee D. Regulation of the B cell receptor repertoire and self-reactivity by BAFF. Journal of Immunology (Baltimore, Md. : 1950). 185: 4128-36. PMID 20817867 DOI: 10.4049/jimmunol.1002176  0.32
2010 Aït-Azzouzene D, Kono DH, Gonzalez-Quintial R, McHeyzer-Williams LJ, Lim M, Wickramarachchi D, Gerdes T, Gavin AL, Skog P, McHeyzer-Williams MG, Nemazee D, Theofilopoulos AN. Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 1015-27. PMID 20554953 DOI: 10.4049/jimmunol.1000698  0.32
2010 Duong BH, Ota T, Aït-Azzouzene D, Aoki-Ota M, Vela JL, Huber C, Walsh K, Gavin AL, Nemazee D. Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen. Journal of Immunology (Baltimore, Md. : 1950). 184: 4143-58. PMID 20231687 DOI: 10.4049/jimmunol.0903564  0.32
2010 Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha. Proceedings of the National Academy of Sciences of the United States of America. 107: 3046-51. PMID 20133626 DOI: 10.1073/pnas.0915098107  0.32
2010 Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, Paulson JC, Paulson J, Nemazee D. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo. The Journal of Experimental Medicine. 207: 173-87. PMID 20038598 DOI: 10.1084/jem.20091873  0.32
2010 Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, Paulson JC, Nemazee D. Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo (Journal of Experimental Medicine (2010), 207, 1, (173-177)) Journal of Experimental Medicine. 207.  0.32
2009 Beck K, Peak MM, Ota T, Nemazee D, Murre C. Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. The Journal of Experimental Medicine. 206: 2271-84. PMID 19752184 DOI: 10.1084/jem.20090756  0.32
2009 Ota T, Aoki-Ota M, Duong BH, Nemazee D. Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE. Journal of Immunology (Baltimore, Md. : 1950). 182: 8110-7. PMID 19494337 DOI: 10.4049/jimmunol.0900300  0.32
2008 Huber C, Mårtensson A, Bokoch GM, Nemazee D, Gavin AL. FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles. The Journal of Biological Chemistry. 283: 34002-12. PMID 18838382 DOI: 10.1074/jbc.M803957200  0.32
2008 Vela JL, Aït-Azzouzene D, Duong BH, Ota T, Nemazee D. Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production. Immunity. 28: 161-70. PMID 18261939 DOI: 10.1016/j.immuni.2007.12.011  0.32
2007 Lamoureux JL, Watson LC, Cherrier M, Skog P, Nemazee D, Feeney AJ. Reduced receptor editing in lupus-prone MRL/lpr mice. The Journal of Experimental Medicine. 204: 2853-64. PMID 17967905 DOI: 10.1084/jem.20071268  0.32
2007 Verkoczy L, Duong B, Skog P, Aït-Azzouzene D, Puri K, Vela JL, Nemazee D. Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. Journal of Immunology (Baltimore, Md. : 1950). 178: 6332-41. PMID 17475862  0.32
2007 Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, et al. Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunology. 19: 216-24. PMID 17398114 DOI: 10.1016/j.smim.2007.02.012  0.32
2007 Vela JL, Nemazee D. Role of RS/kappaDE in B cell receptor editing. Advances in Experimental Medicine and Biology. 596: 169-72. PMID 17338186 DOI: 10.1007/0-387-46530-8_16  0.32
2006 Gavin AL, Hoebe K, Duong B, Ota T, Martin C, Beutler B, Nemazee D. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science (New York, N.Y.). 314: 1936-8. PMID 17185603 DOI: 10.1126/science.1135299  0.32
2006 Nemazee D. Receptor editing in lymphocyte development and central tolerance. Nature Reviews. Immunology. 6: 728-40. PMID 16998507 DOI: 10.1038/nri1939  0.32
2006 Watson LC, Moffatt-Blue CS, McDonald RZ, Kompfner E, Ait-Azzouzene D, Nemazee D, Theofilopoulos AN, Kono DH, Feeney AJ. Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 1120-8. PMID 16818769  0.32
2006 Nemazee D, Gavin A, Hoebe K, Beutler B. Immunology: Toll-like receptors and antibody responses. Nature. 441: E4; discussion E4. PMID 16710369 DOI: 10.1038/nature04875  0.32
2006 Aït-Azzouzene D, Gavin AL, Skog P, Duong B, Nemazee D. Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of Igkappa-reactive macroself antigen. European Journal of Immunology. 36: 985-96. PMID 16511898 DOI: 10.1002/eji.200535581  0.32
2006 Aït-Azzouzene D, Verkoczy L, Duong B, Skog P, Gavin AL, Nemazee D. Split tolerance in peripheral B cell subsets in mice expressing a low level of Igkappa-reactive ligand. Journal of Immunology (Baltimore, Md. : 1950). 176: 939-48. PMID 16393979  0.32
2006 Collins CE, Gavin AL, Migone TS, Hilbert DM, Nemazee D, Stohl W. B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels. Arthritis Research & Therapy. 8: R6. PMID 16356193 DOI: 10.1186/ar1855  0.32
2005 Gavin AL, Duong B, Skog P, Aït-Azzouzene D, Greaves DR, Scott ML, Nemazee D. deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models. Journal of Immunology (Baltimore, Md. : 1950). 175: 319-28. PMID 15972664  0.32
2005 Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, Nemazee D, Ponomarenko JV, Sathiamurthy M, Schoenberger SP, Stewart S, et al. The design and implementation of the immune epitope database and analysis resource. Immunogenetics. 57: 326-36. PMID 15895191 DOI: 10.1007/s00251-005-0803-5  0.32
2005 Verkoczy L, Aït-Azzouzene D, Skog P, Märtensson A, Lang J, Duong B, Nemazee D. A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. Immunity. 22: 519-31. PMID 15845455 DOI: 10.1016/j.immuni.2005.03.006  0.32
2005 Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, Nemazee D, Ponomarenko JV, Sathiamurthy M, Schoenberger S, Stewart S, et al. The immune epitope database and analysis resource: from vision to blueprint. Plos Biology. 3: e91. PMID 15760272 DOI: 10.1371/journal.pbio.0030091  0.32
2005 Ait-Azzouzene D, Verkoczy L, Peters J, Gavin A, Skog P, Vela JL, Nemazee D. An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system. The Journal of Experimental Medicine. 201: 817-28. PMID 15738053 DOI: 10.1084/jem.20041854  0.32
2004 Verkoczy LK, Mårtensson AS, Nemazee D. The scope of receptor editing and its association with autoimmunity. Current Opinion in Immunology. 16: 808-14. PMID 15511677 DOI: 10.1016/j.coi.2004.09.017  0.32
2004 Gavin A, Aït-Azzouzene D, MÃ¥rtensson A, Duong B, Verkoczy L, Vela JL, Skog JL, Skog P, Nemazee D. Peripheral B lymphocyte tolerance. The Keio Journal of Medicine. 53: 151-8. PMID 15477728 DOI: 10.2302/kjm.53.151  0.32
2004 Quong MW, Martensson A, Langerak AW, Rivera RR, Nemazee D, Murre C. Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A. The Journal of Experimental Medicine. 199: 1101-12. PMID 15078898 DOI: 10.1084/jem.20031180  0.32
2004 Silveira PA, Dombrowsky J, Johnson E, Chapman HD, Nemazee D, Serreze DV. B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 172: 5086-94. PMID 15067092  0.32
2004 Aït-Azzouzene D, Skog P, Retter M, Kouskoff V, Hertz M, Lang J, Kench J, Chumley M, Melamed D, Sudaria J, Gavin A, Martensson A, Verkoczy L, Duong B, Vela J, ... Nemazee D, et al. Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection. Immunological Reviews. 197: 219-30. PMID 14962198 DOI: 10.1111/j.0105-2896.2004.0106.x  0.32
2003 Gavin AL, Aït-Azzouzene D, Ware CF, Nemazee D. DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. The Journal of Biological Chemistry. 278: 38220-8. PMID 12867412 DOI: 10.1074/jbc.M306852200  0.32
2003 Pape KA, Kouskoff V, Nemazee D, Tang HL, Cyster JG, Tze LE, Hippen KL, Behrens TW, Jenkins MK. Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. The Journal of Experimental Medicine. 197: 1677-87. PMID 12796466 DOI: 10.1084/jem.20012065  0.32
2003 Nemazee D, Hogquist KA. Antigen receptor selection by editing or downregulation of V(D)J recombination. Current Opinion in Immunology. 15: 182-9. PMID 12633668 DOI: 10.1016/S0952-7915(03)00008-6  0.32
2003 Nemazee D, Gavin A. Do B cells take advantage of 'missing self' recognition? Current Directions in Autoimmunity. 6: 245-64. PMID 12408056  0.32
2002 Nemazee D, Mårtensson A, Verkoczy L. Haplotype exclusion and receptor editing: irreconcilable differences? Seminars in Immunology. 14: 191-8; discussion 22. PMID 12160646 DOI: 10.1016/S1044-5323(02)00042-8  0.32
2001 Kouskoff V, Nemazee D. Role of receptor editing and revision in shaping the B and T lymphocyte repertoire. Life Sciences. 69: 1105-13. PMID 11508343 DOI: 10.1016/S0024-3205(01)01219-X  0.32
2001 Casellas R, Shih TA, Kleinewietfeld M, Rakonjac J, Nemazee D, Rajewsky K, Nussenzweig MC. Contribution of receptor editing to the antibody repertoire. Science (New York, N.Y.). 291: 1541-4. PMID 11222858 DOI: 10.1126/science.291.5508.1541  0.32
2000 Buhl AM, Nemazee D, Cambier JC, Rickert R, Hertz M. B-cell antigen receptor competence regulates B-lymphocyte selection and survival. Immunological Reviews. 176: 141-53. PMID 11043774  0.32
2000 Melamed D, Miri E, Leider N, Nemazee D. Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 4353-8. PMID 11035071  0.32
2000 Nemazee D. Role of B cell antigen receptor in regulation of V(D)J recombination and cell survival. Immunologic Research. 21: 259-63. PMID 10852126 DOI: 10.1385/IR:21:2-3:259  0.32
2000 Nemazee D, Weigert M. Revising B cell receptors. The Journal of Experimental Medicine. 191: 1813-7. PMID 10839798 DOI: 10.1084/jem.191.11.1813  0.32
2000 Nemazee D. Receptor selection in B and T lymphocytes. Annual Review of Immunology. 18: 19-51. PMID 10837051 DOI: 10.1146/annurev.immunol.18.1.19  0.32
2000 Kouskoff V, Lacaud G, Pape K, Retter M, Nemazee D. B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection. Proceedings of the National Academy of Sciences of the United States of America. 97: 7435-9. PMID 10829082 DOI: 10.1073/pnas.130182597  0.32
2000 Chumley MJ, Dal Porto JM, Kawaguchi S, Cambier JC, Nemazee D, Hardy RR. A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. Journal of Immunology (Baltimore, Md. : 1950). 164: 4586-93. PMID 10779761  0.32
2000 Kouskoff V, Lacaud G, Nemazee D. T cell-independent rescue of B lymphocytes from peripheral immune tolerance. Science (New York, N.Y.). 287: 2501-3. PMID 10741972 DOI: 10.1126/science.287.5462.2501  0.32
2000 Lang J, Nemazee D. B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competition. European Journal of Immunology. 30: 689-96. PMID 10671228 DOI: 10.1002/1521-4141(200002)30:2<689::AID-IMMU689>3.0.CO;2-I  0.32
2000 Nemazee D. Receptor editing in B cells. Advances in Immunology. 74: 89-126. PMID 10605605  0.32
2000 Nemazee D, Kouskoff V, Hertz M, Lang J, Melamed D, Pape K, Retter M. B-cell-receptor-dependent positive and negative selection in immature B cells. Current Topics in Microbiology and Immunology. 245: 57-71. PMID 10533318  0.32
1999 Melamed D, Nemazee D. Immunoglobulin transgenes in B lymphocyte development, tolerance, and autoimmunity. Current Directions in Autoimmunity. 1: 1-30. PMID 11791439  0.32
1999 Retter MW, Nemazee D. Receptor editing: genetic reprogramming of autoreactive lymphocytes. Cell Biochemistry and Biophysics. 31: 81-8. PMID 10505669 DOI: 10.1007/BF02738156  0.32
1999 Benschop RJ, Melamed D, Nemazee D, Cambier JC. Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. The Journal of Experimental Medicine. 190: 749-56. PMID 10499913 DOI: 10.1084/jem.190.6.749  0.32
1999 Kench JA, Russell DM, Fadok VA, Young SK, Worthen GS, Jones-Carson J, Henson JE, Henson PM, Nemazee D. Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse. Clinical Immunology (Orlando, Fla.). 92: 300-10. PMID 10479535 DOI: 10.1006/clim.1999.4754  0.32
1999 Nemazee D, Fowlkes BJ. Lymphocyte development: Editorial overview Current Opinion in Immunology. 11: 127-128. DOI: 10.1016/S0952-7915(99)80022-3  0.32
1998 Kouskoff V, Famiglietti S, Lacaud G, Lang P, Rider JE, Kay BK, Cambier JC, Nemazee D. Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. The Journal of Experimental Medicine. 188: 1453-64. PMID 9782122 DOI: 10.1084/jem.188.8.1453  0.32
1998 Retter MW, Nemazee D. Receptor editing occurs frequently during normal B cell development. The Journal of Experimental Medicine. 188: 1231-8. PMID 9763602 DOI: 10.1084/jem.188.7.1231  0.32
1998 Aït-Azzouzene D, Gendron MC, Houdayer M, Langkopf A, Bürki K, Nemazee D, Kanellopoulos-Langevin C. Maternal B lymphocytes specific for paternal histocompatibility antigens are partially deleted during pregnancy. Journal of Immunology (Baltimore, Md. : 1950). 161: 2677-83. PMID 9743323  0.32
1998 Kench JA, Russell DM, Nemazee D. Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes. The Journal of Experimental Medicine. 188: 909-17. PMID 9730892 DOI: 10.1084/jem.188.5.909  0.32
1998 Hertz M, Kouskoff V, Nakamura T, Nemazee D. V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling. Nature. 394: 292-5. PMID 9685161 DOI: 10.1038/28419  0.32
1998 Hertz M, Nemazee D. Receptor editing and commitment in B lymphocytes. Current Opinion in Immunology. 10: 208-13. PMID 9602310 DOI: 10.1016/S0952-7915(98)80250-1  0.32
1998 Nemazee D. Theoretical limits to massive receptor editing in immature B cells. Current Topics in Microbiology and Immunology. 229: 163-71. PMID 9479854  0.32
1998 Melamed D, Benschop RJ, Cambier JC, Nemazee D. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. Cell. 92: 173-82. PMID 9458042 DOI: 10.1016/S0092-8674(00)80912-5  0.32
1998 Aït-Azzouzene D, Gendron MC, Houdayer M, Langkopf A, Bürki K, Nemazee D, Kanellopoulos-Langevin C. Maternal B lymphocytes specific for paternal histo-compatibility antigens are partially deleted during pregnancy Faseb Journal. 12: A883.  0.32
1997 Foster MH, Liu Q, Chen H, Nemazee D, Cooperstone BG. Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies. Autoimmunity. 26: 231-43. PMID 9543184  0.32
1997 Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7: 765-75. PMID 9430222 DOI: 10.1016/S1074-7613(00)80395-7  0.32
1997 Lang J, Arnold B, Hammerling G, Harris AW, Korsmeyer S, Russell D, Strasser A, Nemazee D. Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells. The Journal of Experimental Medicine. 186: 1513-22. PMID 9348309 DOI: 10.1084/jem.186.9.1513  0.32
1997 Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science (New York, N.Y.). 278: 298-301. PMID 9323210 DOI: 10.1126/science.278.5336.298  0.32
1997 Melamed D, Nemazee D. Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest. Proceedings of the National Academy of Sciences of the United States of America. 94: 9267-72. PMID 9256471 DOI: 10.1073/pnas.94.17.9267  0.32
1997 Melamed D, Kench JA, Grabstein K, Rolink A, Nemazee D. A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors. Journal of Immunology (Baltimore, Md. : 1950). 159: 1233-9. PMID 9233618  0.32
1997 Hertz M, Nemazee D. BCR ligation induces receptor editing in IgM+IgD- bone marrow B cells in vitro. Immunity. 6: 429-36. PMID 9133422  0.32
1996 Lang J, Jackson M, Teyton L, Brunmark A, Kane K, Nemazee D. B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. The Journal of Experimental Medicine. 184: 1685-97. PMID 8920858  0.32
1996 Nemazee D. Can receptor editing play an important role in normal B-cell development? Journal of Autoimmunity. 9: 259-61. PMID 8738971 DOI: 10.1006/jaut.1996.0032  0.32
1996 Rubio CF, Kench J, Russell DM, Yawger R, Nemazee D. Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes. Journal of Immunology (Baltimore, Md. : 1950). 157: 65-71. PMID 8683157  0.32
1996 Nemazee D. Antigen receptor 'capacity' and the sensitivity of self-tolerance. Immunology Today. 17: 25-9. PMID 8652047 DOI: 10.1016/0167-5699(96)80565-2  0.32
1995 Nemazee D. Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theory. Annals of the New York Academy of Sciences. 764: 397-401. PMID 7486554  0.32
1994 Spanopoulou E, Roman CA, Corcoran LM, Schlissel MS, Silver DP, Nemazee D, Nussenzweig MC, Shinton SA, Hardy RR, Baltimore D. Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes & Development. 8: 1030-42. PMID 7926785  0.32
1993 Tiegs SL, Russell DM, Nemazee D. Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 177: 1009-20. PMID 8459201  0.32
1993 Nemazee D. Promotion and prevention of autoimmunity by B lymphocytes. Current Opinion in Immunology. 5: 866-72. PMID 8297518 DOI: 10.1016/0952-7915(93)90098-D  0.32
1992 Nemazee D. Mechanisms and meaning of B-lymphocyte tolerance. Research in Immunology. 143: 272-5. PMID 1631404 DOI: 10.1016/S0923-2494(92)80118-5  0.32
1992 Cuende E, Kroemer G, Alonso JM, Nemazee D, Martínez C, Alés-Martínez JE. Inability of IL-2 and IL-10 to counteract B cell clonal deletion. Cellular Immunology. 142: 94-102. PMID 1586962 DOI: 10.1016/0008-8749(92)90271-P  0.32
1991 Russell DM, Dembić Z, Morahan G, Miller JF, Bürki K, Nemazee D. Peripheral deletion of self-reactive B cells. Nature. 354: 308-11. PMID 1956380 DOI: 10.1038/354308a0  0.32
1991 Nemazee D, Russell D, Arnold B, Haemmerling G, Allison J, Miller JF, Morahan G, Buerki K. Clonal deletion of autospecific B lymphocytes. Immunological Reviews. 122: 117-32. PMID 1937539  0.32
1991 Nemazee D, Guiet C, Buerki K, Marshak-Rothstein A. B lymphocytes from the autoimmune-prone mouse strain MLR/lpr manifest an intrinsic defect in tetraparental MRL/lpr in equilibrium DBA/2 chimeras. Journal of Immunology (Baltimore, Md. : 1950). 147: 2536-9. PMID 1918976  0.32
1991 Carbone A, Harbeck R, Dallas A, Nemazee D, Finkel T, O'Brien R, Kubo R, Born W. Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies. Immunological Reviews. 120: 35-50. PMID 1830862  0.32
1989 Nemazee DA, Bürki K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature. 337: 562-6. PMID 2783762 DOI: 10.1038/337562a0  0.32
1989 Nemazee D, Buerki K. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proceedings of the National Academy of Sciences of the United States of America. 86: 8039-43. PMID 2682636  0.32
1987 Rammensee HG, Julius MH, Nemazee D, Langhorne J, Lamers R, Köhler G. Targeting cytotoxic T cells to antigen-specific B lymphocytes. European Journal of Immunology. 17: 433-6. PMID 3494614 DOI: 10.1002/eji.1830170322  0.32
1987 Shlomchik M, Nemazee D, van Snick J, Weigert M. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization. The Journal of Experimental Medicine. 165: 970-87. PMID 3494096  0.32
1986 Shlomchik MJ, Nemazee DA, Sato VL, Van Snick J, Carson DA, Weigert MG. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. The Journal of Experimental Medicine. 164: 407-27. PMID 3088205  0.32
1985 Nemazee DA, Studer S, Steinmetz M, Dembić Z, Kiefer M. The lymphoproliferating cells of MRL-lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen. European Journal of Immunology. 15: 760-4. PMID 4029256 DOI: 10.1002/eji.1830150804  0.32
1985 Wysocki LJ, Margolies MN, Huang B, Nemazee DA, Wechsler DS, Sato VL, Smith JA, Gefter ML. Combinational diversity within variable regions bearing the predominant anti-p-azophenylarsonate idiotype of strain A mice. Journal of Immunology (Baltimore, Md. : 1950). 134: 2740-7. PMID 2982953  0.32
1985 Nemazee DA. Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice. The Journal of Experimental Medicine. 161: 242-56. PMID 2578542  0.32
1983 Nemazee DA, Sato VL. Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response. The Journal of Experimental Medicine. 158: 529-45. PMID 6350525  0.32
1982 Nemazee DA, Sato VL. Enhancing antibody: a novel component of the immune response. Proceedings of the National Academy of Sciences of the United States of America. 79: 3828-32. PMID 6179088  0.32
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