| Year |
Citation |
Score |
| 2023 |
Cimino JX, Zhou M, Waxmonsky J, Mailman RB, Yang Y. Characterization of behavioral changes in T-maze alternation from dopamine D agonists with different receptor coupling mechanisms. Psychopharmacology. PMID 37578525 DOI: 10.1007/s00213-023-06440-5 |
0.409 |
|
| 2022 |
Yang Y, Lewis MM, Huang X, Dokholyan NV, Mailman RB. Dopamine D receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology. The International Journal of Biochemistry & Cell Biology. 148: 106235. PMID 35688404 DOI: 10.1016/j.biocel.2022.106235 |
0.328 |
|
| 2022 |
Yang Y, Lewis MM, Kong L, Mailman RB. A dopamine D agonist vs. methylphenidate in modulating prefrontal cortical working memory. The Journal of Pharmacology and Experimental Therapeutics. PMID 35661631 DOI: 10.1124/jpet.122.001215 |
0.35 |
|
| 2021 |
Weissenrieder JS, Reed JL, Moldovan GL, Johnson MT, Trebak M, Neighbors JD, Mailman RB, Hohl RJ. Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D receptor-dependent, manner. Pharmacology Research & Perspectives. 9: e00689. PMID 34003586 DOI: 10.1002/prp2.689 |
0.372 |
|
| 2020 |
Mailman RB, Yang Y, Huang X. For Publication in The European Journal of Pharmacology D, not D, dopamine receptor activation dramatically improves MPTP-induced parkinsonism unresponsive to levodopa. European Journal of Pharmacology. 173760. PMID 33279520 DOI: 10.1016/j.ejphar.2020.173760 |
0.408 |
|
| 2020 |
Huang X, Lewis MM, Van Scoy LJ, De Jesus S, Eslinger PJ, Arnold AC, Miller AJ, Fernandez-Mendoza J, Snyder B, Harrington W, Kong L, Wang X, Sun D, Delnomdedieu M, Duvvuri S, ... ... Mailman R, et al. The D1/D5 Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease: A Feasibility Study. Journal of Parkinson's Disease. PMID 32986682 DOI: 10.3233/JPD-202188 |
0.328 |
|
| 2020 |
Yang Y, Mailman RB. Dopamine D
1
Agonists, Working Memory, and the Prefrontal Cortex: Effect of Receptor Functional Selectivity/Signaling Bias The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.02381 |
0.454 |
|
| 2019 |
Weissenrieder JS, Neighbors JD, Mailman RB, Hohl RJ. Cancer and the dopamine D2 receptor: a pharmacological perspective. The Journal of Pharmacology and Experimental Therapeutics. PMID 31000578 DOI: 10.1124/Jpet.119.256818 |
0.399 |
|
| 2018 |
Yang Y, Lee SM, Imamura F, Gowda K, Amin S, Mailman RB. D1 dopamine receptors intrinsic activity and functional selectivity affect working memory in prefrontal cortex. Molecular Psychiatry. PMID 30532019 DOI: 10.1038/s41380-018-0312-1 |
0.428 |
|
| 2018 |
Baladi MG, Forster MJ, Gatch MB, Mailman RB, Hyman DL, Carter LP, Janowsky AJ. Characterization of the neurochemical and behavioral effects of solriamfetol (JZP-110), a selective dopamine and norepinephrine reuptake inhibitor. The Journal of Pharmacology and Experimental Therapeutics. PMID 29891587 DOI: 10.1124/Jpet.118.248120 |
0.328 |
|
| 2016 |
Arnsten AF, Girgis RR, Gray DL, Mailman RB. Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia. Biological Psychiatry. PMID 26946382 DOI: 10.1016/j.biopsych.2015.12.028 |
0.419 |
|
| 2015 |
Rosell DR, Zaluda LC, McClure MM, Perez-Rodriguez MM, Strike KS, Barch DM, Harvey PD, Girgis RR, Hazlett EA, Mailman RB, Abi-Dargham A, Lieberman JA, Siever LJ. Effects of the D1 dopamine receptor agonist dihydrexidine (DAR-0100A) on working memory in schizotypal personality disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 446-53. PMID 25074637 DOI: 10.1038/Npp.2014.192 |
0.396 |
|
| 2014 |
Lee SM, Yang Y, Mailman RB. Dopamine D1 receptor signaling: does GαQ-phospholipase C actually play a role? The Journal of Pharmacology and Experimental Therapeutics. 351: 9-17. PMID 25052835 DOI: 10.1124/jpet.114.214411 |
0.509 |
|
| 2014 |
Lee SM, Kant A, Blake D, Murthy V, Boyd K, Wyrick SJ, Mailman RB. SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C. Neuropharmacology. 86: 145-54. PMID 24929112 DOI: 10.1016/j.neuropharm.2014.05.042 |
0.552 |
|
| 2014 |
Mailman RB, Leeson S. CHEMICAL, MOLECULAR, AND CELLULAR FACTORS INFLUENCING THE DISCOVERY AND DEVELOPMENT OF DOPAMINE D1 AGONISTS Schizophrenia Research. 153: S6-S7. DOI: 10.1016/S0920-9964(14)70020-9 |
0.456 |
|
| 2012 |
Boyd KN, Mailman RB. Dopamine receptor signaling and current and future antipsychotic drugs. Handbook of Experimental Pharmacology. 53-86. PMID 23129328 DOI: 10.1007/978-3-642-25761-2_3 |
0.502 |
|
| 2012 |
Fowler JC, Bhattacharya S, Urban JD, Vaidehi N, Mailman RB. Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations. Molecular Pharmacology. 81: 820-31. PMID 22416052 DOI: 10.1124/Mol.111.075457 |
0.802 |
|
| 2012 |
Boyd KN, Mailman RB. D1/D5 Dopamine Agonists as Pharmacotherapy for Schizophrenia Targets and Emerging Therapies For Schizophrenia. 51-84. DOI: 10.1002/9781118309421.ch3 |
0.34 |
|
| 2010 |
Mailman RB, Murthy V. Ligand functional selectivity advances our understanding of drug mechanisms and drug discovery. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 345-6. PMID 20010712 DOI: 10.1038/npp.2009.117 |
0.401 |
|
| 2010 |
Mailman RB, Murthy V. Third generation antipsychotic drugs: partial agonism or receptor functional selectivity? Current Pharmaceutical Design. 16: 488-501. PMID 19909227 DOI: 10.2174/138161210790361461 |
0.464 |
|
| 2010 |
NEGASH K, NICHOLS DE, WATTS VJ, MAILMAN RB. ChemInform Abstract: Further Definition of the D1 Dopamine Receptor Pharmacophore: Synthesis of trans-6,6a,7,8,9,13b-Hexahydro-5H-benzo(d)naphth(2,1-b) azepines as Rigid Analogues of β-Phenyldopamine. Cheminform. 28: no-no. DOI: 10.1002/chin.199741209 |
0.343 |
|
| 2010 |
GHOSH D, SNYDER SE, WATTS VJ, MAILMAN RB, NICHOLS DE. ChemInform Abstract: 8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph(1,2,3-de)isoquinoline: A Potent Full Dopamine D1 Agonist Containing a Rigid β- Phenyldopamine Pharmacophore. Cheminform. 27: no-no. DOI: 10.1002/chin.199619167 |
0.316 |
|
| 2010 |
Mailman RB, Vrana KE. Chemical Perspective on Neurotransmission and Drug Discovery for the Central Nervous System Burger's Medicinal Chemistry and Drug Discovery. 1-14. DOI: 10.1002/0471266949.Bmc245 |
0.369 |
|
| 2009 |
Brown JT, Kant A, Mailman RB. Rapid, semi-automated, and inexpensive radioimmunoassay of cAMP: application in GPCR-mediated adenylate cyclase assays. Journal of Neuroscience Methods. 177: 261-6. PMID 19007813 DOI: 10.1016/J.Jneumeth.2008.10.016 |
0.537 |
|
| 2007 |
Mailman RB, Huang X. Dopamine receptor pharmacology. Handbook of Clinical Neurology. 83: 77-105. PMID 18808911 DOI: 10.1016/S0072-9752(07)83004-1 |
0.489 |
|
| 2007 |
Mailman RB. GPCR functional selectivity has therapeutic impact. Trends in Pharmacological Sciences. 28: 390-6. PMID 17629962 DOI: 10.1016/j.tips.2007.06.002 |
0.454 |
|
| 2007 |
Mu Q, Johnson K, Morgan PS, Grenesko EL, Molnar CE, Anderson B, Nahas Z, Kozel FA, Kose S, Knable M, Fernandes P, Nichols DE, Mailman RB, George MS. A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia. Schizophrenia Research. 94: 332-41. PMID 17596915 DOI: 10.1016/J.Schres.2007.03.033 |
0.452 |
|
| 2007 |
George MS, Molnar CE, Grenesko EL, Anderson B, Mu Q, Johnson K, Nahas Z, Knable M, Fernandes P, Juncos J, Huang X, Nichols DE, Mailman RB. A single 20 mg dose of dihydrexidine (DAR-0100), a full dopamine D1 agonist, is safe and tolerated in patients with schizophrenia. Schizophrenia Research. 93: 42-50. PMID 17467956 DOI: 10.1016/J.Schres.2007.03.011 |
0.363 |
|
| 2007 |
Ryman-Rasmussen JP, Griffith A, Oloff S, Vaidehi N, Brown JT, Goddard WA, Mailman RB. Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors. Neuropharmacology. 52: 562-75. PMID 17067639 DOI: 10.1016/J.Neuropharm.2006.08.028 |
0.818 |
|
| 2007 |
Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB. Functional selectivity and classical concepts of quantitative pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 320: 1-13. PMID 16803859 DOI: 10.1124/Jpet.106.104463 |
0.759 |
|
| 2007 |
Urban JD, Vargas GA, von Zastrow M, Mailman RB. Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 67-77. PMID 16554739 DOI: 10.1038/Sj.Npp.1301071 |
0.801 |
|
| 2006 |
Leonard SK, Ferry-Leeper P, Mailman RB. Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors. Brain Research. 1117: 25-37. PMID 16962565 DOI: 10.1016/J.Brainres.2006.08.024 |
0.758 |
|
| 2006 |
Lewis MM, Huang X, Nichols DE, Mailman RB. D1 and functionally selective dopamine agonists as neuroprotective agents in Parkinson's disease. Cns & Neurological Disorders Drug Targets. 5: 345-53. PMID 16787233 DOI: 10.2174/187152706777452245 |
0.417 |
|
| 2005 |
Oloff S, Mailman RB, Tropsha A. Application of validated QSAR models of D1 dopaminergic antagonists for database mining. Journal of Medicinal Chemistry. 48: 7322-32. PMID 16279792 DOI: 10.1021/Jm049116M |
0.773 |
|
| 2005 |
Ryman-Rasmussen JP, Nichols DE, Mailman RB. Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists. Molecular Pharmacology. 68: 1039-48. PMID 15985612 DOI: 10.1124/mol.105.012153 |
0.529 |
|
| 2004 |
Gay EA, Urban JD, Nichols DE, Oxford GS, Mailman RB. Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: evidence for induction of ligand-specific receptor states. Molecular Pharmacology. 66: 97-105. PMID 15213300 DOI: 10.1124/Mol.66.1.97 |
0.783 |
|
| 2004 |
Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE. 8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms. Bioorganic & Medicinal Chemistry. 12: 1403-12. PMID 15018913 DOI: 10.1016/J.Bmc.2004.01.008 |
0.819 |
|
| 2004 |
Sit SY, Xie K, Jacutin-Porte S, Boy KM, Seanz J, Taber MT, Gulwadi AG, Korpinen CD, Burris KD, Molski TF, Ryan E, Xu C, Verdoorn T, Johnson G, Nichols DE, ... Mailman RB, et al. Synthesis and SAR exploration of dinapsoline analogues. Bioorganic & Medicinal Chemistry. 12: 715-34. PMID 14759732 DOI: 10.1016/j.bmc.2003.11.015 |
0.492 |
|
| 2004 |
Mailman RB, Gay EA. Novel mechanisms of drug action: Functional selectivity at D2 dopamine receptors (a lesson for drug discovery) Medicinal Chemistry Research. 13: 115-126. DOI: 10.1007/s00044-004-0017-7 |
0.495 |
|
| 2003 |
Leonard SK, Anderson CM, Lachowicz JE, Schulz DW, Kilts CD, Mailman RB. Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase. Synapse (New York, N.Y.). 50: 320-33. PMID 14556237 DOI: 10.1002/Syn.10272 |
0.775 |
|
| 2003 |
Shapiro DA, Renock S, Arrington E, Chiodo LA, Liu LX, Sibley DR, Roth BL, Mailman R. Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1400-11. PMID 12784105 DOI: 10.1038/sj.npp.1300203 |
0.457 |
|
| 2003 |
Qandil AM, Lewis MM, Jassen A, Leonard SK, Mailman RB, Nichols DE. Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands. Bioorganic & Medicinal Chemistry. 11: 1451-64. PMID 12628671 DOI: 10.1016/S0968-0896(02)00561-8 |
0.782 |
|
| 2003 |
Leonard SK, Petitto JM, Anderson CM, Mooney DH, Lachowicz JE, Schulz DW, Kilts CD, Mailman RB. D1 dopamine receptors in the amygdala exhibit unique properties Annals of the New York Academy of Sciences. 985: 536-539. DOI: 10.1111/J.1749-6632.2003.Tb07121.X |
0.776 |
|
| 2002 |
Andersson C, Hamer RM, Lawler CP, Mailman RB, Lieberman JA. Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 143-51. PMID 12093588 DOI: 10.1016/S0893-133X(02)00412-8 |
0.312 |
|
| 2002 |
Kilts JD, Connery HS, Arrington EG, Lewis MM, Lawler CP, Oxford GS, O'Malley KL, Todd RD, Blake BL, Nichols DE, Mailman RB. Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs. The Journal of Pharmacology and Experimental Therapeutics. 301: 1179-89. PMID 12023553 DOI: 10.1124/jpet.301.3.1179 |
0.563 |
|
| 2002 |
Mottola DM, Kilts JD, Lewis MM, Connery HS, Walker QD, Jones SR, Booth RG, Hyslop DK, Piercey M, Wightman RM, Lawler CP, Nichols DE, Mailman RB. Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase. The Journal of Pharmacology and Experimental Therapeutics. 301: 1166-78. PMID 12023552 DOI: 10.1124/jpet.301.3.1166 |
0.579 |
|
| 2001 |
Mailman R, Huang X, Nichols DE. Parkinson's disease and D1 dopamine receptors. Current Opinion in Investigational Drugs (London, England : 2000). 2: 1582-91. PMID 11763161 |
0.426 |
|
| 2001 |
Huang X, Lawler CP, Lewis MM, Nichols DE, Mailman RB. D1 dopamine receptors. International Review of Neurobiology. 48: 65-139. PMID 11526741 DOI: 10.1016/S0074-7742(01)48014-7 |
0.523 |
|
| 2001 |
Miyamoto S, Mailman RB, Lieberman JA, Duncan GE. Blunted brain metabolic response to ketamine in mice lacking D(1A) dopamine receptors. Brain Research. 894: 167-80. PMID 11251190 DOI: 10.1016/S0006-8993(01)01991-6 |
0.467 |
|
| 2001 |
Montague DM, Striplin CD, Overcash JS, Drago J, Lawler CP, Mailman RB. Quantification of D1B(D5) receptors in dopamine D1A receptor-deficient mice. Synapse (New York, N.Y.). 39: 319-22. PMID 11169782 DOI: 10.1002/1098-2396(20010315)39:4<319::AID-SYN1015>3.0.CO;2-1 |
0.518 |
|
| 2001 |
Gulwadi AG, Korpinen CD, Mailman RB, Nichols DE, Sit SY, Taber MT. Dinapsoline: characterization of a D1 dopamine receptor agonist in a rat model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 296: 338-44. PMID 11160615 |
0.44 |
|
| 2000 |
Miyamoto S, Mailman R, Drago J, Lieberman J, Duncan G. 145. Blunted brain metabolic response to ketamine in mice lacking D1A dopamine receptors Biological Psychiatry. 47: S44. DOI: 10.1016/S0006-3223(00)00407-8 |
0.398 |
|
| 1999 |
Montague DM, Lawler CP, Mailman RB, Gilmore JH. Developmental regulation of the dopamine D1 receptor in human caudate and putamen. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 641-9. PMID 10516960 DOI: 10.1016/S0893-133X(99)00062-7 |
0.521 |
|
| 1999 |
Hoffman B, Cho SJ, Zheng W, Wyrick S, Nichols DE, Mailman RB, Tropsha A. Quantitative structure-activity relationship modeling of dopamine D(1) antagonists using comparative molecular field analysis, genetic algorithms-partial least-squares, and K nearest neighbor methods. Journal of Medicinal Chemistry. 42: 3217-26. PMID 10464009 DOI: 10.1021/jm980415j |
0.399 |
|
| 1999 |
Lawler CP, Prioleau C, Lewis MM, Mak C, Jiang D, Schetz JA, Gonzalez AM, Sibley DR, Mailman RB. Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 612-27. PMID 10327430 DOI: 10.1016/S0893-133X(98)00099-2 |
0.548 |
|
| 1999 |
Doll MK, Nichols DE, Kilts JD, Prioleau C, Lawler CP, Lewis MM, Mailman RB. Synthesis and dopaminergic properties of benzo-fused analogues of quinpirole and quinelorane. Journal of Medicinal Chemistry. 42: 935-40. PMID 10072690 DOI: 10.1021/jm9804533 |
0.525 |
|
| 1998 |
Lieberman JA, Mailman RB, Duncan G, Sikich L, Chakos M, Nichols DE, Kraus JE. Serotonergic basis of antipsychotic drug effects in schizophrenia. Biological Psychiatry. 44: 1099-117. PMID 9836014 DOI: 10.1016/S0006-3223(98)00187-5 |
0.303 |
|
| 1998 |
Duncan GE, Leipzig JN, Mailman RB, Lieberman JA. Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation. Brain Research. 812: 65-75. PMID 9813244 DOI: 10.1016/S0006-8993(98)00926-3 |
0.375 |
|
| 1998 |
Mailman RB, Nichols DE. Dopamine D1 receptor agonists as antiparkinson drugs. Trends in Pharmacological Sciences. 19: 255-6. PMID 9703756 DOI: 10.1016/S0165-6147(98)01219-X |
0.427 |
|
| 1998 |
Smith DR, Striplin CD, Geller AM, Mailman RB, Drago J, Lawler CP, Gallagher M. Behavioural assessment of mice lacking D1A dopamine receptors. Neuroscience. 86: 135-46. PMID 9692749 DOI: 10.1016/S0306-4522(97)00608-8 |
0.383 |
|
| 1998 |
Lewis MM, Watts VJ, Lawler CP, Nichols DE, Mailman RB. Homologous desensitization of the D1A dopamine receptor: efficacy in causing desensitization dissociates from both receptor occupancy and functional potency. The Journal of Pharmacology and Experimental Therapeutics. 286: 345-53. PMID 9655879 |
0.453 |
|
| 1998 |
Monte AP, Marona-Lewicka D, Lewis MM, Mailman RB, Wainscott DB, Nelson DL, Nichols DE. Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity. Journal of Medicinal Chemistry. 41: 2134-45. PMID 9622555 DOI: 10.1021/jm980076u |
0.484 |
|
| 1997 |
Negash K, Nichols DE, Watts VJ, Mailman RB. Further definition of the D1 dopamine receptor pharmacophore: synthesis of trans-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphth[2,1-b]azepines as rigid analogues of beta-phenyldopamine. Journal of Medicinal Chemistry. 40: 2140-7. PMID 9216832 DOI: 10.1021/Jm970157A |
0.487 |
|
| 1997 |
Smith HP, Nichols DE, Mailman RB, Lawler CP. Locomotor inhibition, yawning and vacuous chewing induced by a novel dopamine D2 post-synaptic receptor agonist. European Journal of Pharmacology. 323: 27-36. PMID 9105873 DOI: 10.1016/S0014-2999(97)00026-5 |
0.54 |
|
| 1996 |
Walker QD, Mailman RB. Triadimefon and triadimenol: effects on monoamine uptake and release. Toxicology and Applied Pharmacology. 139: 227-33. PMID 8806838 DOI: 10.1006/taap.1996.0161 |
0.398 |
|
| 1996 |
Mottola DM, Laiter S, Watts VJ, Tropsha A, Wyrick SD, Nichols DE, Mailman RB. Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping. Journal of Medicinal Chemistry. 39: 285-96. PMID 8568818 DOI: 10.1021/Jm9502100 |
0.539 |
|
| 1996 |
Ghosh D, Snyder SE, Watts VJ, Mailman RB, Nichols DE. 9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: a potent full dopamine D1 agonist containing a rigid-beta-phenyldopamine pharmacophore. Journal of Medicinal Chemistry. 39: 549-55. PMID 8558526 DOI: 10.1021/Jm950707+ |
0.552 |
|
| 1995 |
Lawler CP, Gilmore JH, Watts VJ, Walker QD, Southerland SB, Cook LL, Mathis CA, Mailman RB. Interhemispheric modulation of dopamine receptor interactions in unilateral 6-OHDA rodent model. Synapse (New York, N.Y.). 21: 299-311. PMID 8869160 DOI: 10.1002/Syn.890210404 |
0.504 |
|
| 1995 |
Watts VJ, Lawler CP, Gonzales AJ, Zhou QY, Civelli O, Nichols DE, Mailman RB. Spare receptors and intrinsic activity: studies with D1 dopamine receptor agonists. Synapse (New York, N.Y.). 21: 177-87. PMID 8584979 DOI: 10.1002/syn.890210211 |
0.536 |
|
| 1995 |
Brewster WK, Nichols DE, Watts VJ, Riggs RM, Mottola D, Mailman RB. Evaluation of cis- and trans-9- and 11-hydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridines as structurally rigid, selective D1 dopamine receptor ligands. Journal of Medicinal Chemistry. 38: 318-27. PMID 7830274 DOI: 10.1021/Jm00002A013 |
0.509 |
|
| 1995 |
Heidenreich BA, Mailman RB, Nichols DE, Napier TC. Partial and full dopamine D1 agonists produce comparable increases in ventral pallidal neuronal activity: contribution of endogenous dopamine. The Journal of Pharmacology and Experimental Therapeutics. 273: 516-25. PMID 7714807 |
0.384 |
|
| 1995 |
Gariépy JL, Gendreau PL, Mailman RB, Tancer M, Lewis MH. Rearing conditions alter social reactivity and D1 dopamine receptors in high- and low-aggressive mice. Pharmacology, Biochemistry, and Behavior. 51: 767-73. PMID 7675857 DOI: 10.1016/0091-3057(95)00028-U |
0.449 |
|
| 1995 |
Knoerzer TA, Watts VJ, Nichols DE, Mailman RB. Synthesis and biological evaluation of a series of substituted benzo[a]phenanthridines as agonists at D1 and D2 dopamine receptors. Journal of Medicinal Chemistry. 38: 3062-70. PMID 7636869 DOI: 10.1021/Jm00016A009 |
0.525 |
|
| 1995 |
Snyder SE, Aviles-Garay FA, Chakraborti R, Nichols DE, Watts VJ, Mailman RB. Synthesis and evaluation of 6,7-dihydroxy-2,3,4,8,9,13b-hexahydro-1H- benzo[6,7]cyclohepta[1,2,3-ef][3]benzazepine, 6,7-dihydroxy- 1,2,3,4,8,12b-hexahydroanthr[10,4a,4-cd]azepine, and 10-(aminomethyl)-9,10- dihydro-1,2-dihydroxyanthracene as conformationally restricted analogs of beta-phenyldopamine. Journal of Medicinal Chemistry. 38: 2395-409. PMID 7608904 DOI: 10.1021/Jm00013A015 |
0.466 |
|
| 1995 |
Watts VJ, Lawler CP, Fox DR, Neve KA, Nichols DE, Mailman RB. LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors. Psychopharmacology. 118: 401-9. PMID 7568626 DOI: 10.1007/Bf02245940 |
0.562 |
|
| 1995 |
Gilmore JH, Watts VJ, Lawler CP, Noll EP, Nichols DE, Mailman RB. "Full" dopamine D1 agonists in human caudate: biochemical properties and therapeutic implications. Neuropharmacology. 34: 481-8. PMID 7566481 DOI: 10.1016/0028-3908(95)00014-W |
0.547 |
|
| 1995 |
Wyrick SD, Booth RG, Myers AM, Owens CE, Bucholtz EC, Hooper PC, Kula NS, Baldessarini RJ, Mailman RB. 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes and related derivatives as ligands for the neuromodulatory sigma 3 receptor: further structure-activity relationships. Journal of Medicinal Chemistry. 38: 3857-64. PMID 7562917 DOI: 10.1021/jm00019a016 |
0.541 |
|
| 1994 |
Hudkins RL, Mailman RB, DeHaven-Hudkins DL. Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds. Journal of Medicinal Chemistry. 37: 1964-70. PMID 8027978 DOI: 10.1021/Jm00039A008 |
0.4 |
|
| 1994 |
Minor DL, Wyrick SD, Charifson PS, Watts VJ, Nichols DE, Mailman RB. Synthesis and molecular modeling of 1-phenyl-1,2,3,4-tetrahydroisoquinolines and related 5,6,8,9-tetrahydro-13bH-dibenzo[a,h]quinolizines as D1 dopamine antagonists. Journal of Medicinal Chemistry. 37: 4317-28. PMID 7996543 DOI: 10.1021/Jm00051A008 |
0.532 |
|
| 1994 |
Knoerzer TA, Nichols DE, Brewster WK, Watts VJ, Mottola D, Mailman RB. Dopaminergic benzo[a]phenanthridines: resolution and pharmacological evaluation of the enantiomers of dihydrexidine, the full efficacy D1 dopamine receptor agonist. Journal of Medicinal Chemistry. 37: 2453-60. PMID 7914538 DOI: 10.1021/Jm00041A025 |
0.55 |
|
| 1994 |
Lewis MH, Gariépy JL, Gendreau P, Nichols DE, Mailman RB. Social reactivity and D1 dopamine receptors: studies in mice selectively bred for high and low levels of aggression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 10: 115-22. PMID 7912934 DOI: 10.1038/npp.1994.13 |
0.397 |
|
| 1994 |
Hudkins RL, Mailman RB, DeHaven-Hudkins DL. RLH-033, a novel, potent and selective ligand for the sigma 1 recognition site. European Journal of Pharmacology. 271: 235-6. PMID 7698207 DOI: 10.1016/0014-2999(94)90286-0 |
0.449 |
|
| 1994 |
Wyrick SD, Myers AM, Booth RG, Kula NS, Baldessarini RJ, Mailman RB. Synthesis of [N-C3H3]-trans-(1R,3S)-(-)-1-phenyl-3-N,N-dimethylamino-1,2,3,4-tetr ahydronaphthalene (H2-PAT) Journal of Labelled Compounds and Radiopharmaceuticals. 34: 131-134. DOI: 10.1002/jlcr.2580340205 |
0.444 |
|
| 1993 |
Gilmore JH, Lawler CP, Eaton AM, Mailman RB. Postmortem stability of dopamine D1 receptor mRNA and D1 receptors. Brain Research. Molecular Brain Research. 18: 290-6. PMID 8326824 DOI: 10.1016/0169-328X(93)90092-4 |
0.502 |
|
| 1993 |
Lawler CP, Gilmore JH, Mooney DH, Mayleben MA, Atashi JR, Mileson BE, Wyrick SD, Mailman RB. A rapid and efficient method for the radiosynthesis and purification of [125I]SCH23982. Journal of Neuroscience Methods. 49: 141-53. PMID 8271827 DOI: 10.1016/0165-0270(93)90118-B |
0.407 |
|
| 1993 |
Booth RG, Wyrick SD, Baldessarini RJ, Kula NS, Myers AM, Mailman RB. New sigma-like receptor recognized by novel phenylaminotetralins: ligand binding and functional studies. Molecular Pharmacology. 44: 1232-9. PMID 8264560 |
0.385 |
|
| 1993 |
Watts VJ, Lawler CP, Knoerzer T, Mayleben MA, Neve KA, Nichols DE, Mailman RB. Hexahydrobenzo[a]phenanthridines: novel dopamine D3 receptor ligands. European Journal of Pharmacology. 239: 271-3. PMID 8223910 DOI: 10.1016/0014-2999(93)91012-C |
0.563 |
|
| 1993 |
Wyrick SD, Booth RG, Myers AM, Owens CE, Kula NS, Baldessarini RJ, McPhail AT, Mailman RB. Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity. Journal of Medicinal Chemistry. 36: 2542-51. PMID 8102651 DOI: 10.1021/jm00069a013 |
0.464 |
|
| 1993 |
Watts VJ, Lawler CP, Gilmore JH, Southerland SB, Nichols DE, Mailman RB. Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents. European Journal of Pharmacology. 242: 165-72. PMID 7902811 DOI: 10.1016/0014-2999(93)90076-T |
0.535 |
|
| 1992 |
Mottola DM, Brewster WK, Cook LL, Nichols DE, Mailman RB. Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. The Journal of Pharmacology and Experimental Therapeutics. 262: 383-93. PMID 1352553 |
0.456 |
|
| 1991 |
Bishop JE, Mathis CA, Gerdes JM, Whitney JM, Eaton AM, Mailman RB. Synthesis and in vitro evaluation of 2,3-dimethoxy-5-(fluoroalkyl)-substituted benzamides: high-affinity ligands for CNS dopamine D2 receptors. Journal of Medicinal Chemistry. 34: 1612-24. PMID 1827843 DOI: 10.1021/Jm00109A013 |
0.508 |
|
| 1991 |
Lovenberg TW, Roth RH, Nichols DE, Mailman RB. D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors. Journal of Neurochemistry. 57: 1563-9. PMID 1717649 DOI: 10.1111/J.1471-4159.1991.Tb06352.X |
0.54 |
|
| 1991 |
Mileson BE, Lewis MH, Mailman RB. Dopamine receptor 'supersensitivity' occurring without receptor up-regulation. Brain Research. 561: 1-10. PMID 1686741 DOI: 10.1016/0006-8993(91)90742-E |
0.421 |
|
| 1991 |
Darney KJ, Lewis MH, Brewster WK, Nichols DE, Mailman RB. Behavioral effects in the rat of dihydrexidine, a high-potency, full-efficacy D1 dopamine receptor agonist. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 5: 187-95. PMID 1684499 |
0.408 |
|
| 1991 |
Elsworth JD, Lawrence MS, Roth RH, Taylor JR, Mailman RB, Nichols DE, Lewis MH, Redmond DE. D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey. The Journal of Pharmacology and Experimental Therapeutics. 259: 595-600. PMID 1682479 |
0.412 |
|
| 1991 |
Lovenberg TW, Nichols DE, Nestler EJ, Roth RH, Mailman RB. Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors. Brain Research. 556: 101-7. PMID 1682005 DOI: 10.1016/0006-8993(91)90552-7 |
0.4 |
|
| 1991 |
Taylor JR, Lawrence MS, Redmond DE, Elsworth JD, Roth RH, Nichols DE, Mailman RB. Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys. European Journal of Pharmacology. 199: 389-91. PMID 1680717 DOI: 10.1016/0014-2999(91)90508-N |
0.44 |
|
| 1990 |
Walker QD, Lewis MH, Crofton KM, Mailman RB. Triadimefon, a triazole fungicide, induces stereotyped behavior and alters monoamine metabolism in rats. Toxicology and Applied Pharmacology. 102: 474-85. PMID 2315916 DOI: 10.1016/0041-008X(90)90043-T |
0.449 |
|
| 1990 |
Brewster WK, Nichols DE, Riggs RM, Mottola DM, Lovenberg TW, Lewis MH, Mailman RB. trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist. Journal of Medicinal Chemistry. 33: 1756-64. PMID 1971308 DOI: 10.1021/Jm00168A034 |
0.545 |
|
| 1990 |
Lewis MH, Gluck JP, Beauchamp AJ, Keresztury MF, Mailman RB. Long-term effects of early social isolation in Macaca mulatta: changes in dopamine receptor function following apomorphine challenge. Brain Research. 513: 67-73. PMID 1693540 DOI: 10.1016/0006-8993(90)91089-Y |
0.366 |
|
| 1989 |
Niedzwiecki DM, Cubeddu LX, Mailman RB. Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum. The Journal of Pharmacology and Experimental Therapeutics. 250: 117-25. PMID 2746491 |
0.328 |
|
| 1989 |
Lovenberg TW, Brewster WK, Mottola DM, Lee RC, Riggs RM, Nichols DE, Lewis MH, Mailman RB. Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist. European Journal of Pharmacology. 166: 111-3. PMID 2572425 DOI: 10.1016/0014-2999(89)90690-0 |
0.544 |
|
| 1989 |
Charifson PS, Bowen JP, Wyrick SD, Hoffman AJ, Cory M, McPhail AT, Mailman RB. Conformational analysis and molecular modeling of 1-phenyl-, 4-phenyl-, and 1-benzyl-1,2,3,4-tetrahydroisoquinolines as D1 dopamine receptor ligands. Journal of Medicinal Chemistry. 32: 2050-8. PMID 2527994 DOI: 10.1021/Jm00129A006 |
0.35 |
|
| 1988 |
Kilts CD, Anderson CM, Ely TD, Mailman RB. The biochemistry and pharmacology of mesoamygdaloid dopamine neurons. Annals of the New York Academy of Sciences. 537: 173-87. PMID 3059923 DOI: 10.1111/J.1749-6632.1988.Tb42105.X |
0.349 |
|
| 1988 |
Charifson PS, Wyrick SD, Hoffman AJ, Simmons RM, Bowen JP, McDougald DL, Mailman RB. Synthesis and pharmacological characterization of 1-phenyl-, 4-phenyl-, and 1-benzyl-1,2,3,4-tetrahydroisoquinolines as dopamine receptor ligands. Journal of Medicinal Chemistry. 31: 1941-6. PMID 3050089 DOI: 10.1021/Jm00118A012 |
0.527 |
|
| 1988 |
DeHaven-Hudkins DL, Schulz DW, Walsh TJ, Mailman RB. Responses of dopaminergic and serotonergic systems to triethyllead intoxication. Neurotoxicology and Teratology. 10: 279-85. PMID 2465482 DOI: 10.1016/0892-0362(88)90029-3 |
0.582 |
|
| 1987 |
Konkol RJ, Chapman L, Breese GR, Collier AM, Kilts C, Finley C, Vogel RR, Mailman RB, Bendeich EG. Hemophilus influenzae meningitis in the rat: behavioral, electrophysiological, and biochemical consequences. Annals of Neurology. 21: 353-60. PMID 3579220 DOI: 10.1002/Ana.410210407 |
0.316 |
|
| 1987 |
Mailman RB. Mechanisms of CNS injury in behavioral dysfunction. Neurotoxicology and Teratology. 9: 417-26. PMID 3325802 DOI: 10.1016/0892-0362(87)90054-7 |
0.362 |
|
| 1987 |
Crofton KM, Reiter LW, Mailman RB. Pyrethroid insecticides and radioligand displacement from the GABA receptor chloride ionophore complex. Toxicology Letters. 35: 183-90. PMID 3029901 DOI: 10.1016/0378-4274(87)90205-0 |
0.314 |
|
| 1986 |
Rollema H, Feenstra MG, Grol CJ, Lewis MH, Staples L, Mailman RB. S(-)DP-5,6-ADTN as an in vivo dopamine receptor ligand: relation between displacement by dopamine agonists and their pharmacological effects. Naunyn-Schmiedeberg's Archives of Pharmacology. 332: 338-45. PMID 3736679 DOI: 10.1007/BF00500084 |
0.503 |
|
| 1986 |
Twery MJ, Kirkpatrick B, Critcher EC, Lewis MH, Mailman RB, Cooper CW. Motor effects of calcitonin administered intracerebroventricularly in the rat. European Journal of Pharmacology. 121: 189-98. PMID 3699092 DOI: 10.1016/0014-2999(86)90490-5 |
0.349 |
|
| 1986 |
Napier TC, Givens BS, Schulz DW, Bunney BS, Breese GR, Mailman RB. SCH23390 effects on apomorphine-induced responses of nigral dopaminergic neurons. The Journal of Pharmacology and Experimental Therapeutics. 236: 838-45. PMID 3512819 |
0.386 |
|
| 1986 |
Mailman RB, Schulz DW, Kilts CD, Lewis MH, Rollema H, Wyrick S. The multiplicity of the D1 dopamine receptor. Advances in Experimental Medicine and Biology. 204: 53-72. PMID 2947430 DOI: 10.1007/978-1-4684-5191-7_4 |
0.48 |
|
| 1986 |
Mailman RB, Schulz DW, Kilts CD, Lewis MH, Rollema H, Wyrick S. Multiple forms of the D1 dopamine receptor: its linkage to adenylate cyclase and psychopharmacological effects. Psychopharmacology Bulletin. 22: 593-8. PMID 2879302 |
0.439 |
|
| 1985 |
Schulz DW, Staples L, Mailman RB. SCH23390 causes persistent antidopaminergic effects in vivo: evidence for longterm occupation of receptors. Life Sciences. 36: 1941-8. PMID 3887084 DOI: 10.1016/0024-3205(85)90443-6 |
0.526 |
|
| 1985 |
Schulz DW, Stanford EJ, Wyrick SW, Mailman RB. Binding of [3H]SCH23390 in rat brain: regional distribution and effects of assay conditions and GTP suggest interactions at a D1-like dopamine receptor. Journal of Neurochemistry. 45: 1601-11. PMID 2864398 DOI: 10.1111/J.1471-4159.1985.Tb07233.X |
0.465 |
|
| 1985 |
Wyrick SD, Mailman RB. Tritium labelled (±)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepine (SCH23390) Journal of Labelled Compounds and Radiopharmaceuticals. 22: 189-195. DOI: 10.1002/JLCR.2580220212 |
0.473 |
|
| 1984 |
Schulz DW, Lewis MH, Petitto J, Mailman RB. Ascorbic acid decreases [(3)H]dopamine binding in striatum without inhibiting dopamine-sensitive adenylate cyclase. Neurochemistry International. 6: 117-21. PMID 20488029 DOI: 10.1016/0197-0186(84)90035-4 |
0.411 |
|
| 1984 |
Walsh TJ, Tilson HA, DeHaven DL, Mailman RB, Fisher A, Hanin I. AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex, and produces long-term passive avoidance and radial-arm maze deficits in the rat. Brain Research. 321: 91-102. PMID 6548653 DOI: 10.1016/0006-8993(84)90684-X |
0.441 |
|
| 1984 |
Kilts CD, Knight DL, Mailman RB, Widerlöv E, Breese GR. Effects of thioridazine and its metabolites on dopaminergic function: drug metabolism as a determinant of the antidopaminergic actions of thioridazine. The Journal of Pharmacology and Experimental Therapeutics. 231: 334-42. PMID 6491985 |
0.335 |
|
| 1984 |
Schulz DW, Wyrick SD, Mailman RB. [3H]SCH23390 has the characteristics of a dopamine receptor ligand in the rat central nervous system. European Journal of Pharmacology. 106: 211-2. PMID 6397360 DOI: 10.1016/0014-2999(84)90701-5 |
0.445 |
|
| 1984 |
Schulz DW, Mailman RB. An improved, automated adenylate cyclase assay utilizing preparative HPLC: effects of phosphodiesterase inhibitors. Journal of Neurochemistry. 42: 764-74. PMID 6319607 DOI: 10.1111/J.1471-4159.1984.Tb02748.X |
0.365 |
|
| 1984 |
Mailman RB, Schulz DW, Lewis MH, Staples L, Rollema H, Dehaven DL. SCH-23390: a selective D1 dopamine antagonist with potent D2 behavioral actions. European Journal of Pharmacology. 101: 159-60. PMID 6235121 DOI: 10.1016/0014-2999(84)90044-X |
0.489 |
|
| 1984 |
DeHaven DL, Walsh TJ, Mailman RB. Effects of trimethyltin on dopaminergic and serotonergic function in the central nervous system. Toxicology and Applied Pharmacology. 75: 182-9. PMID 6206607 DOI: 10.1016/0041-008X(84)90200-X |
0.496 |
|
| 1984 |
Mailman RB, Rollema H, Schulz DW. Dopamine receptor multiplicity: When the D1 antagonist is a D2 antagonist Federation Proceedings. 43: no. 4737. |
0.455 |
|
| 1983 |
Twery MJ, Cooper CW, Mailman RB. Calcitonin depresses amphetamine-induced locomotor activity. Pharmacology, Biochemistry, and Behavior. 18: 857-62. PMID 6889413 DOI: 10.1016/S0091-3057(83)80005-7 |
0.331 |
|
| 1983 |
Mailman RB, Krigman MR, Frye GD, Hanin I. Effects of postnatal trimethyltin or triethyltin treatment on CNS catecholamine, GABA, and acetylcholine systems in the rat. Journal of Neurochemistry. 40: 1423-9. PMID 6834067 DOI: 10.1111/J.1471-4159.1983.Tb13585.X |
0.322 |
|
| 1983 |
Nemeroff CB, Luttinger D, Hernandez DE, Mailman RB, Mason GA, Davis SD, Widerlöv E, Frye GD, Kilts CA, Beaumont K, Breese GR, Prange AJ. Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies. The Journal of Pharmacology and Experimental Therapeutics. 225: 337-45. PMID 6682440 |
0.317 |
|
| 1983 |
Mailman RB. Lithium-induced polydipsia: dependence on nigrostriatal dopamine pathway and relationship to changes in the renin-angiotensin system. Psychopharmacology. 80: 143-9. PMID 6410443 DOI: 10.1007/BF00427958 |
0.374 |
|
| 1981 |
Kuhn CM, Vogel RA, Mailman RB, Mueller RA, Schanberg SM, Breese GR. Effect of 5,7-dihydroxytryptamine on serotonergic control of prolactin secretion and behavior in rats. Psychopharmacology. 73: 188-93. PMID 6785814 DOI: 10.1007/Bf00429216 |
0.374 |
|
| 1981 |
Ondrusek MG, Kilts CD, Frye GD, Mailman RB, Mueller RA, Breese GR. Behavioral and biochemical studies of the scopolamine-induced reversal of neuroleptic activity. Psychopharmacology. 73: 17-22. PMID 6112768 DOI: 10.1007/Bf00431093 |
0.399 |
|
| 1980 |
Mailman RB, Ferris RM, Tang FL, Vogel RA, Kilts CD, Lipton MA, Smith DA, Mueller RA, Breese GR. Erythrosine (Red No. 3) and its nonspecific biochemical actions: what relation to behavioral changes? Science (New York, N.Y.). 207: 535-7. PMID 7352264 DOI: 10.1126/Science.7352264 |
0.373 |
|
| 1980 |
Pappas BA, Breese GR, Mailman RB, Mueller RA. Importance of the Locus coeruleus and involvement of alpha-adrenergic receptors in the post-decapitation reflex in the rat. Psychopharmacology. 69: 163-71. PMID 6256789 DOI: 10.1007/Bf00427644 |
0.348 |
|
| 1979 |
Harden TK, Mailman RB, Mueller RA, Breese GR. Noradrenergic hyperinnervation reduces the density of beta-adrenergic receptors in rat cerebellum. Brain Research. 166: 194-8. PMID 217500 DOI: 10.1016/0006-8993(79)90664-4 |
0.327 |
|
| 1978 |
Breese GR, Mailman RB, Ondrusek MG, Harden TK, Mueller RA. Effects of dopaminergic agonists and antagonists on cerebellar guanosine-3',5'-monophosphate (cGMP). Life Sciences. 23: 533-6. PMID 29192 DOI: 10.1016/0024-3205(78)90167-4 |
0.424 |
|
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