Year |
Citation |
Score |
2020 |
Wahlberg LU, Emerich DF, Kordower JH, Bell W, Fradet T, Paolone G. Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain. Current Research in Pharmacology and Drug Discovery. 1: 19-29. PMID 34909639 DOI: 10.1016/j.crphar.2020.04.001 |
0.304 |
|
2019 |
Orive G, Echave MC, Pedraz JL, Golafshan N, Dolatshahi-Pirouz A, Paolone G, Emerich D. Advances in cell-laden hydrogels for delivering therapeutics. Expert Opinion On Biological Therapy. 1-4. PMID 31414944 DOI: 10.1080/14712598.2019.1654452 |
0.324 |
|
2019 |
Emerich DF, Kordower JH, Chu Y, Thanos C, Bintz B, Paolone G, Wahlberg LU. Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity. Neural Plasticity. 2019: 6286197. PMID 30984255 DOI: 10.1155/2019/6286197 |
0.403 |
|
2019 |
Paolone G, Falcicchia C, Lovisari F, Kokaia M, Bell WJ, Fradet T, Barbieri M, Wahlberg LU, Emerich DF, Simonato M. Long-term, targeted delivery of GDNF from encapsulated cells is neuroprotective and reduces seizures in the pilocarpine model of epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30665947 DOI: 10.1523/JNEUROSCI.0435-18.2018 |
0.332 |
|
2018 |
Orive G, Santos-Vizcaino E, Pedraz JL, Hernandez RM, Vela Ramirez JE, Dolatshahi-Pirouz A, Khademhosseini A, Peppas NA, Emerich DF. 3D cell-laden polymers to release bioactive products in the eye. Progress in Retinal and Eye Research. PMID 30342088 DOI: 10.1016/J.Preteyeres.2018.10.002 |
0.312 |
|
2018 |
Savolainen M, Emerich D, Kordower JH. Disease Modification Through Trophic Factor Delivery. Methods in Molecular Biology (Clifton, N.J.). 1780: 525-547. PMID 29856034 DOI: 10.1007/978-1-4939-7825-0_24 |
0.364 |
|
2018 |
Falcicchia C, Paolone G, Emerich DF, Lovisari F, Bell WJ, Fradet T, Wahlberg LU, Simonato M. Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy. Molecular Therapy. Methods & Clinical Development. 9: 211-224. PMID 29766029 DOI: 10.1016/j.omtm.2018.03.001 |
0.329 |
|
2018 |
Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P. Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes. Trends in Biotechnology. PMID 29455936 DOI: 10.1016/J.Tibtech.2018.01.007 |
0.335 |
|
2017 |
Sandrof MA, Emerich DF, Thanos CG. Primary Choroid Plexus Tissue for Use in Cellular Therapy. Methods in Molecular Biology (Clifton, N.J.). 1479: 237-249. PMID 27738941 DOI: 10.1007/978-1-4939-6364-5_19 |
0.346 |
|
2015 |
Orive G, Santos E, Poncelet D, Hernández RM, Pedraz JL, Wahlberg LU, De Vos P, Emerich D. Cell encapsulation: technical and clinical advances. Trends in Pharmacological Sciences. PMID 26067102 DOI: 10.1016/J.Tips.2015.05.003 |
0.333 |
|
2014 |
Emerich DF, Orive G, Thanos C, Tornoe J, Wahlberg LU. Encapsulated cell therapy for neurodegenerative diseases: from promise to product. Advanced Drug Delivery Reviews. 67: 131-41. PMID 23880505 DOI: 10.1016/J.Addr.2013.07.008 |
0.377 |
|
2012 |
Tornøe J, Torp M, Jørgensen JR, Emerich DF, Thanos C, Bintz B, Fjord-Larsen L, Wahlberg LU. Encapsulated cell-based biodelivery of meteorin is neuroprotective in the quinolinic acid rat model of neurodegenerative disease. Restorative Neurology and Neuroscience. 30: 225-36. PMID 22426041 DOI: 10.3233/RNN-2012-110199 |
0.416 |
|
2012 |
Zanin MP, Pettingill LN, Harvey AR, Emerich DF, Thanos CG, Shepherd RK. The development of encapsulated cell technologies as therapies for neurological and sensory diseases. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 3-13. PMID 22285549 DOI: 10.1016/J.Jconrel.2012.01.021 |
0.384 |
|
2012 |
Fjord-Larsen L, Kusk P, Emerich DF, Thanos C, Torp M, Bintz B, Tornøe J, Johnsen AH, Wahlberg LU. Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer. Gene Therapy. 19: 1010-7. PMID 22113314 DOI: 10.1038/gt.2011.178 |
0.369 |
|
2011 |
Ali OA, Doherty E, Bell WJ, Fradet T, Hudak J, Laliberte MT, Mooney DJ, Emerich DF. The efficacy of intracranial PLG-based vaccines is dependent on direct implantation into brain tissue. Journal of Controlled Release : Official Journal of the Controlled Release Society. 154: 249-57. PMID 21704093 DOI: 10.1016/J.Jconrel.2011.06.021 |
0.306 |
|
2011 |
Emerich DF, Orive G, Borlongan C. Tales of biomaterials, molecules, and cells for repairing and treating brain dysfunction. Current Stem Cell Research & Therapy. 6: 171-89. PMID 21476979 DOI: 10.2174/157488811796575350 |
0.364 |
|
2011 |
Thanos CG, Bintz BE, Goddard M, Boekelheide K, Hall S, Emerich DF. Functional modulation of choroid plexus epithelial clusters in vitro for tissue repair applications. Cell Transplantation. 20: 1659-72. PMID 21396169 DOI: 10.3727/096368911X564985 |
0.332 |
|
2011 |
Jørgensen JR, Emerich DF, Thanos C, Thompson LH, Torp M, Bintz B, Fjord-Larsen L, Johansen TE, Wahlberg LU. Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model. Neurobiology of Disease. 41: 160-8. PMID 20840868 DOI: 10.1016/j.nbd.2010.09.003 |
0.407 |
|
2010 |
Emerich DF, Silva E, Ali O, Mooney D, Bell W, Yu SJ, Kaneko Y, Borlongan C. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplantation. 19: 1063-71. PMID 20412616 DOI: 10.3727/096368910X498278 |
0.313 |
|
2010 |
Thanos CG, Bintz B, Emerich DF. Microencapsulated choroid plexus epithelial cell transplants for repair of the brain. Advances in Experimental Medicine and Biology. 670: 80-91. PMID 20384220 DOI: 10.1007/978-1-4419-5786-3_8 |
0.348 |
|
2010 |
Emerich DF, Mooney DJ, Storrie H, Babu RS, Kordower JH. Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease. Neurotoxicity Research. 17: 66-74. PMID 19588214 DOI: 10.1007/S12640-009-9079-0 |
0.374 |
|
2009 |
Thanos CG, Emerich DF, Bintz BE, Goddard M, Mills J, Jensen R, Lombardi M, Hall S, Boekelheide K. Secreted products from the porcine choroid plexus accelerate the healing of cutaneous wounds. Cell Transplantation. 18: 1395-409. PMID 19660181 DOI: 10.3727/096368909X12483162197402 |
0.326 |
|
2009 |
Emerich DF, Borlongan CV. Potential of choroid plexus epithelial cell grafts for neuroprotection in Huntington's disease: what remains before considering clinical trials. Neurotoxicity Research. 15: 205-11. PMID 19384593 DOI: 10.1007/s12640-009-9021-5 |
0.39 |
|
2008 |
Emerich DF, Thanos CG, Sanberg PR. Intraventricular implant of encapsulated CNTF-secreting fibroblasts ameliorates motor deficits in aged rats. Current Aging Science. 1: 105-11. PMID 20021379 DOI: 10.2174/1874609810801020105 |
0.323 |
|
2008 |
Thanos CG, Emerich DF. On the use of hydrogels in cell encapsulation and tissue engineering system. Recent Patents On Drug Delivery & Formulation. 2: 19-24. PMID 19075894 DOI: 10.2174/187221108783331384 |
0.315 |
|
2008 |
Borlongan CV, Thanos CG, Skinner SJ, Geaney M, Emerich DF. Transplants of encapsulated rat choroid plexus cells exert neuroprotection in a rodent model of Huntington's disease. Cell Transplantation. 16: 987-92. PMID 18351014 DOI: 10.3727/000000007783472426 |
0.307 |
|
2007 |
Borlongan CV, Thanos CG, Skinner SJM, Geaney M, Emerich DF. Transplants of Encapsulated Rat Choroid Plexus Cells Exert Neuroprotection in a Rodent Model of Huntington's Disease. Cell Transplantation. 16: 987-992. PMID 28866919 DOI: 10.3727/000000007783472426 |
0.417 |
|
2007 |
Borlongan CV, Masuda T, Walker TA, Maki M, Hara K, Yasuhara T, Matsukawa N, Emerich DF. Nanotechnology as an adjunct tool for transplanting engineered cells and tissues. Current Molecular Medicine. 7: 609-18. PMID 18045140 DOI: 10.2174/156652407782564381 |
0.381 |
|
2007 |
Emerich DF, Schneider P, Bintz B, Hudak J, Thanos CG. Aging reduces the neuroprotective capacity, VEGF secretion, and metabolic activity of rat choroid plexus epithelial cells. Cell Transplantation. 16: 697-705. PMID 18019359 DOI: 10.3727/000000007783465145 |
0.425 |
|
2007 |
Emerich DF, Schneider P, Bintz B, Hudak J, Thanos CG. In vitro exposure of cultured porcine choroid plexus epithelial cells to immunosuppressant, anti-inflammatory, and psychoactive drugs. Cell Transplantation. 16: 435-40. PMID 17658133 DOI: 10.3727/000000007783464867 |
0.395 |
|
2006 |
Emerich DF, Thanos CG. In vitro culture duration does not impact the ability of encapsulated choroid plexus transplants to prevent neurological deficits in an excitotoxin-lesioned rat model of Huntington's disease. Cell Transplantation. 15: 595-602. PMID 17176611 DOI: 10.3727/000000006783981657 |
0.437 |
|
2006 |
Halberstadt C, Emerich DF, Gonsalves K. Combining cell therapy and nanotechnology. Expert Opinion On Biological Therapy. 6: 971-81. PMID 16989579 DOI: 10.1517/14712598.6.10.971 |
0.379 |
|
2006 |
Emerich DF, Thanos CG, Goddard M, Skinner SJ, Geany MS, Bell WJ, Bintz B, Schneider P, Chu Y, Babu RS, Borlongan CV, Boekelheide K, Hall S, Bryant B, Kordower JH. Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys. Neurobiology of Disease. 23: 471-80. PMID 16777422 DOI: 10.1016/J.Nbd.2006.04.014 |
0.393 |
|
2006 |
Skinner SJ, Geaney MS, Rush R, Rogers ML, Emerich DF, Thanos CG, Vasconcellos AV, Tan PL, Elliott RB. Choroid plexus transplants in the treatment of brain diseases. Xenotransplantation. 13: 284-8. PMID 16768721 DOI: 10.1111/J.1399-3089.2006.00310.X |
0.396 |
|
2006 |
Emerich DF, Thanos CG. Intracompartmental delivery of CNTF as therapy for Huntington's disease and retinitis pigmentosa. Current Gene Therapy. 6: 147-59. PMID 16475952 DOI: 10.2174/156652306775515547 |
0.391 |
|
2005 |
Emerich DF, Skinner SJ, Borlongan CV, Thanos CG. A role of the choroid plexus in transplantation therapy. Cell Transplantation. 14: 715-25. PMID 16454346 DOI: 10.3727/000000005783982576 |
0.347 |
|
2005 |
Halberstadt CR, Williams D, Emerich D, Goddard M, Vasconcellos AV, Curry W, Bhatia A, Gores PF. Subcutaneous transplantation of islets into streptozocin-induced diabetic rats. Cell Transplantation. 14: 595-605. PMID 16355568 DOI: 10.3727/000000005783982792 |
0.335 |
|
2005 |
Thanos C, Emerich D. Delivery of neurotrophic factors and therapeutic proteins for retinal diseases Expert Opinion On Biological Therapy. 5: 1443-1452. PMID 16255648 DOI: 10.1517/14712598.5.11.1443 |
0.352 |
|
2005 |
Hemendinger R, Wang J, Malik S, Persinski R, Copeland J, Emerich D, Gores P, Halberstadt C, Rosenfeld J. Sertoli cells improve survival of motor neurons in SOD1 transgenic mice, a model of amyotrophic lateral sclerosis. Experimental Neurology. 196: 235-43. PMID 16242126 DOI: 10.1016/J.Expneurol.2005.07.025 |
0.368 |
|
2005 |
Emerich DF, Skinner SJ, Borlongan CV, Vasconcellos AV, Thanos CG. The choroid plexus in the rise, fall and repair of the brain. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 27: 262-74. PMID 15714561 DOI: 10.1002/bies.20193 |
0.33 |
|
2004 |
Newman MB, Emerich DF, Borlongan CV, Sanberg CD, Sanberg PR. Use of human umbilical cord blood (HUCB) cells to repair the damaged brain. Current Neurovascular Research. 1: 269-81. PMID 16181077 DOI: 10.2174/1567202043362261 |
0.35 |
|
2004 |
Emerich DF. Dose-dependent neurochemical and functional protection afforded by encapsulated CNTF-producing cells. Cell Transplantation. 13: 839-44. PMID 15690987 DOI: 10.3727/000000004783983404 |
0.333 |
|
2004 |
Emerich DF. The convergence of cell transplantation and nanoengineering. Cell Transplantation. 13: 477-9. PMID 15565859 DOI: 10.3727/000000004783983657 |
0.329 |
|
2004 |
Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. Neuroprotection by encapsulated choroid plexus in a rodent model of Huntington's disease. Neuroreport. 15: 2521-5. PMID 15538187 DOI: 10.1097/00001756-200411150-00018 |
0.411 |
|
2004 |
Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke. Stroke; a Journal of Cerebral Circulation. 35: 2206-10. PMID 15284450 DOI: 10.1161/01.STR.0000138954.25825.0b |
0.376 |
|
2004 |
Borlongan CV, Emerich DF. Eleventh Annual Conference of the American Society for Neural Transplantation and Repair. Expert Opinion On Biological Therapy. 4: 1351-5. PMID 15268668 DOI: 10.1517/14712598.4.8.1351 |
0.331 |
|
2004 |
Emerich DF, Vasconcellos AV, Elliott RB, Skinner SJ, Borlongan CV. The choroid plexus: function, pathology and therapeutic potential of its transplantation. Expert Opinion On Biological Therapy. 4: 1191-201. PMID 15268655 DOI: 10.1517/14712598.4.8.1191 |
0.358 |
|
2004 |
Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. CNS grafts of rat choroid plexus protect against cerebral ischemia in adult rats. Neuroreport. 15: 1543-7. PMID 15232280 DOI: 10.1097/01.wnr.0000133298.84901.cf |
0.367 |
|
2004 |
Emerich DF, Winn SR. Neuroprotective effects of encapsulated CNTF-producing cells in a rodent model of Huntington's disease are dependent on the proximity of the implant to the lesioned striatum. Cell Transplantation. 13: 253-9. PMID 15191163 DOI: 10.3727/000000004783983981 |
0.415 |
|
2004 |
Halberstadt C, Emerich DF, Gores P. Use of Sertoli cell transplants to provide local immunoprotection for tissue grafts. Expert Opinion On Biological Therapy. 4: 813-25. PMID 15174964 DOI: 10.1517/14712598.4.6.813 |
0.382 |
|
2004 |
Emerich DF. Sertoli cell grafts for Huntington's disease. An opinion. Neurotoxicity Research. 5: 567. PMID 15111233 DOI: 10.1007/BF03033176 |
0.363 |
|
2004 |
Dufour JM, Gores P, Hemendinger R, Emerich DF, Halberstadt CR. Transgenic Sertoli cells as a vehicle for gene therapy. Cell Transplantation. 13: 1-6. PMID 15040599 DOI: 10.3727/000000004772664833 |
0.314 |
|
2004 |
Newman MB, Davis CD, Borlongan CV, Emerich D, Sanberg PR. Transplantation of human umbilical cord blood cells in the repair of CNS diseases. Expert Opinion On Biological Therapy. 4: 121-30. PMID 14998772 DOI: 10.1517/14712598.4.2.121 |
0.389 |
|
2004 |
Dufour JM, Hemendinger R, Halberstadt CR, Gores P, Emerich DF, Korbutt GS, Rajotte RV. Genetically engineered Sertoli cells are able to survive allogeneic transplantation. Gene Therapy. 11: 694-700. PMID 14724669 DOI: 10.1038/sj.gt.3302218 |
0.326 |
|
2003 |
Emerich DF, Hemendinger R, Halberstadt CR. The testicular-derived Sertoli cell: cellular immunoscience to enable transplantation. Cell Transplantation. 12: 335-49. PMID 12911122 DOI: 10.3727/000000003108746894 |
0.384 |
|
2003 |
Blanchet PJ, Konitsiotis S, Mochizuki H, Pluta R, Emerich DF, Chase TN, Mouradian MM. Complications of a trophic xenotransplant approach in parkinsonian monkeys. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 607-12. PMID 12787846 DOI: 10.1016/S0278-5846(03)00048-4 |
0.423 |
|
2003 |
Borlongan CV, Emerich DF. Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport. Brain Research Bulletin. 60: 297-306. PMID 12754091 DOI: 10.1016/S0361-9230(03)00043-1 |
0.323 |
|
2003 |
Salzberg-Brenhouse HC, Chen EY, Emerich DF, Baldwin S, Hogeland K, Ranelli S, Lafreniere D, Perdomo B, Novak L, Kladis T, Fu K, Basile AS, Kordower JH, Bartus RT. Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. The Journal of Pharmacology and Experimental Therapeutics. 306: 218-28. PMID 12676885 DOI: 10.1124/Jpet.103.049700 |
0.308 |
|
2002 |
Emerich DF. Islet transplantation for diabetes: current status and future prospects. Expert Opinion On Biological Therapy. 2: 793-803. PMID 12517259 DOI: 10.1517/14712598.2.8.793 |
0.34 |
|
2002 |
Borlongan CV, Emerich DF, Hoffer BJ, Bartus RT. Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6-hydroxydopamine neurotoxicity. Brain Research. 956: 211-20. PMID 12445688 DOI: 10.1016/S0006-8993(02)03474-1 |
0.328 |
|
2002 |
Emerich DF, Sanberg PR. Novel means to selectively identify Sertoli cell transplants. Cell Transplantation. 11: 495-7. PMID 12428737 DOI: 10.3727/000000002783985594 |
0.326 |
|
2002 |
Emerich DF, Winn SR, Bartus RT. Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats. Cell Transplantation. 11: 47-54. PMID 12095219 DOI: 10.3727/096020198389771 |
0.346 |
|
2002 |
Emerich DF, Winn SR, Bartus RT. Injection of chemotherapeutic microspheres and glioma. III: Parameters to optimize efficacy. Cell Transplantation. 11: 35-45. PMID 12095218 DOI: 10.3727/096020198389762 |
0.317 |
|
2002 |
Emerich DF, Dean RL, Bartus RT. The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct? Experimental Neurology. 173: 168-81. PMID 11771949 DOI: 10.1006/exnr.2001.7835 |
0.317 |
|
2001 |
Emerich DF. Neuroprotective possibilities for Huntington's disease. Expert Opinion On Biological Therapy. 1: 467-79. PMID 11727519 DOI: 10.1517/14712598.1.3.467 |
0.307 |
|
2001 |
Emerich DF, Winn SR. Immunoisolation cell therapy for CNS diseases. Critical Reviews in Therapeutic Drug Carrier Systems. 18: 265-98. PMID 11442201 DOI: 10.1615/Critrevtherdrugcarriersyst.V18.I3.10 |
0.359 |
|
2001 |
Emerich DF, Salzberg HC. Update on immunoisolation cell therapy for CNS diseases. Cell Transplantation. 10: 3-24. PMID 11294469 DOI: 10.3727/000000001783986981 |
0.375 |
|
2001 |
Emerich DF, Dean RL, Osborn C, Bartus RT. The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation. Clinical Pharmacokinetics. 40: 105-23. PMID 11286321 DOI: 10.2165/00003088-200140020-00003 |
0.318 |
|
2000 |
Emerich DF, Dean RL, Marsh J, Pink M, Lafreniere D, Snodgrass P, Bartus RT. Intravenous cereport (RMP-7) enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain. Pharmaceutical Research. 17: 1212-9. PMID 11145226 DOI: 10.1023/A:1026462629438 |
0.318 |
|
2000 |
Lindner MD, Francis JM, Plone MA, McDermott PE, Frydel BR, Emerich DF, Saydoff JA. The analgesic potential of intraventricular polymer-encapsulated adrenal chromaffin cells in a rodent model of chronic neuropathic pain. Experimental and Clinical Psychopharmacology. 8: 524-38. PMID 11127424 DOI: 10.1037//1064-1297.8.4.524 |
0.31 |
|
2000 |
Emerich DF, Winn SR, Snodgrass P, LaFreniere D, Agostino M, Wiens T, Xiong H, Bartus RT. Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors. Pharmaceutical Research. 17: 776-81. PMID 10990194 DOI: 10.1023/A:1007591721877 |
0.301 |
|
2000 |
Emerich DF, Winn SR, Hu Y, Marsh J, Snodgrass P, LaFreniere D, Wiens T, Hasler BP, Bartus RT. Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors. Pharmaceutical Research. 17: 767-75. PMID 10990193 DOI: 10.1023/A:1007576405039 |
0.339 |
|
1999 |
Dean RL, Emerich DF, Hasler BP, Bartus RT. Cereport (RMP-7) increases carboplatin levels in brain tumors after pretreatment with dexamethasone. Neuro-Oncology. 1: 268-74. PMID 11550318 DOI: 10.1093/Neuonc/1.4.268 |
0.303 |
|
1999 |
Emerich DF. Encapsulated CNTF-producing cells for Huntington's disease. Cell Transplantation. 8: 581-2. PMID 10701486 DOI: 10.1177/096368979900800603 |
0.318 |
|
1999 |
Kordower JH, Isacson O, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Experimental Neurology. 159: 4-20. PMID 10486171 DOI: 10.1006/Exnr.1999.7156 |
0.358 |
|
1999 |
Lindner MD, Cain CK, Plone MA, Frydel BR, Blaney TJ, Emerich DF, Hoane MR. Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats. Behavioural Brain Research. 102: 1-16. PMID 10403011 DOI: 10.1016/S0166-4328(98)00160-0 |
0.339 |
|
1999 |
Emerich DF, Snodgrass P, Dean R, Agostino M, Hasler B, Pink M, Xiong H, Kim BS, Bartus RT. Enhanced delivery of carboplatin into brain tumours with intravenous Cereport (RMP-7): dramatic differences and insight gained from dosing parameters. British Journal of Cancer. 80: 964-70. PMID 10362103 DOI: 10.1038/Sj.Bjc.6690450 |
0.308 |
|
1999 |
Emerich DF, Tracy MA, Ward KL, Figueiredo M, Qian R, Henschel C, Bartus RT. Biocompatibility of poly (DL-lactide-co-glycolide) microspheres implanted into the brain. Cell Transplantation. 8: 47-58. PMID 10338275 DOI: 10.1177/096368979900800114 |
0.333 |
|
1998 |
Emerich DF, Snodgrass P, Pink M, Bloom F, Bartus RT. Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport (RMP-7). Brain Research. 801: 259-66. PMID 9729419 DOI: 10.1016/S0006-8993(98)00571-X |
0.325 |
|
1998 |
Emerich DF, Bruhn S, Chu Y, Kordower JH. Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease. Cell Transplantation. 7: 213-25. PMID 9588602 DOI: 10.1016/S0963-6897(97)00163-2 |
0.416 |
|
1998 |
Lindner MD, Emerich DF. Therapeutic potential of a polymer-encapsulated L-DOPA and dopamine-producing cell line in rodent and primate models of Parkinson's disease. Cell Transplantation. 7: 165-74. PMID 9588598 DOI: 10.1016/S0963-6897(97)00169-3 |
0.373 |
|
1998 |
Lindner MD, Plone MA, Cain CK, Frydel B, Francis JM, Emerich DF, Sutton RL. Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions. Journal of Neurotrauma. 15: 199-216. PMID 9528920 DOI: 10.1089/Neu.1998.15.199 |
0.304 |
|
1997 |
Lindner MD, Plone MA, Frydel B, Kaplan FA, Krueger PM, Bell WJ, Blaney TJ, Winn SR, Sherman SS, Doherty EJ, Emerich DF. Intraventricular encapsulated calf adrenal chromaffin cells: viable for at least 500 days in vivo without detectable adverse effects on behavioral/cognitive function or host immune sensitization in rats. Restorative Neurology and Neuroscience. 11: 21-35. PMID 21551525 DOI: 10.3233/RNN-1997-111203 |
0.405 |
|
1997 |
Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP. Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice. Experimental Neurology. 148: 187-204. PMID 9398461 DOI: 10.1006/Exnr.1997.6657 |
0.395 |
|
1997 |
Subramanian T, Emerich DF, Bakay RA, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates. Cell Transplantation. 6: 469-77. PMID 9331498 DOI: 10.1016/S0963-6897(97)00049-3 |
0.326 |
|
1997 |
Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK. Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease. The Journal of Comparative Neurology. 387: 96-113. PMID 9331174 DOI: 10.1002/(Sici)1096-9861(19971013)387:1<96::Aid-Cne8>3.0.Co;2-I |
0.414 |
|
1997 |
Date I, Shingo T, Ohmoto T, Emerich DF. Long-term enhanced chromaffin cell survival and behavioral recovery in hemiparkinsonian rats with co-grafted polymer-encapsulated human NGF-secreting cells. Experimental Neurology. 147: 10-7. PMID 9294398 DOI: 10.1006/exnr.1997.6579 |
0.414 |
|
1997 |
Lindner MD, Plone MA, Mullins TD, Winn SR, Chandonait SE, Stott JA, Blaney TJ, Sherman SS, Emerich DF. Somatic delivery of catecholamines in the striatum attenuate parkinsonian symptoms and widen the therapeutic window of oral sinemet in rats. Experimental Neurology. 145: 130-40. PMID 9184116 DOI: 10.1006/exnr.1997.6456 |
0.356 |
|
1997 |
Emerich DF, Cain CK, Greco C, Saydoff JA, Hu ZY, Liu H, Lindner MD. Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease. Cell Transplantation. 6: 249-66. PMID 9171158 DOI: 10.1016/S0963-6897(97)00035-3 |
0.438 |
|
1997 |
Emerich DF, Winn SR, Hantraye PM, Peschanski M, Chen EY, Chu Y, McDermott P, Baetge EE, Kordower JH. Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature. 386: 395-9. PMID 9121555 DOI: 10.1038/386395A0 |
0.367 |
|
1997 |
Lindner MD, Plone MA, Francis JM, Blaney TJ, Salamone JD, Emerich DF. Rats with partial striatal dopamine depletions exhibit robust and long-lasting behavioral deficits in a simple fixed-ratio bar-pressing task. Behavioural Brain Research. 86: 25-40. PMID 9105579 DOI: 10.1016/S0166-4328(96)02240-1 |
0.321 |
|
1996 |
Lindner MD, Plone MA, Francis JM, Emerich DF. Validation of a rodent model of Parkinson's Disease: evidence of a therapeutic window for oral Sinemet. Brain Research Bulletin. 39: 367-72. PMID 9138746 DOI: 10.1016/0361-9230(96)00027-5 |
0.334 |
|
1996 |
Date I, Ohmoto T, Imaoka T, Shingo T, Emerich DF. Chromaffin cell survival from both young and old donors is enhanced by co-grafts of polymer-encapsulated human NGF-secreting cells. Neuroreport. 7: 1813-8. PMID 8905671 DOI: 10.1097/00001756-199607290-00025 |
0.404 |
|
1996 |
Emerich DF, Winn SR, Lindner MD. Continued presence of intrastriatal but not intraventricular polymer-encapsulated PC12 cells is required for alleviation of behavioral deficits in Parkinsonian rodents. Cell Transplantation. 5: 589-96. PMID 8889217 DOI: 10.1016/0963-6897(96)00086-3 |
0.369 |
|
1996 |
Date I, Ohmoto T, Imaoka T, Ono T, Hammang JP, Francis J, Greco C, Emerich DF. Cografting with polymer-encapsulated human nerve growth factor-secreting cells and chromaffin cell survival and behavioral recovery in hemiparkinsonian rats. Journal of Neurosurgery. 84: 1006-12. PMID 8847564 DOI: 10.3171/jns.1996.84.6.1006 |
0.428 |
|
1996 |
Emerich DF, Lindner MD, Winn SR, Chen EY, Frydel BR, Kordower JH. Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5168-81. PMID 8756445 DOI: 10.1523/Jneurosci.16-16-05168.1996 |
0.452 |
|
1996 |
Winn SR, Lindner MD, Lee A, Haggett G, Francis JM, Emerich DF. Polymer-encapsulated genetically modified cells continue to secrete human nerve growth factor for over one year in rat ventricles: behavioral and anatomical consequences. Experimental Neurology. 140: 126-38. PMID 8690056 DOI: 10.1006/exnr.1996.0123 |
0.417 |
|
1996 |
Lindner MD, Kearns CE, Winn SR, Frydel B, Emerich DF. Effects of intraventricular encapsulated hNGF-secreting fibroblasts in aged rats. Cell Transplantation. 5: 205-23. PMID 8689032 DOI: 10.1016/0963-6897(95)02029-2 |
0.355 |
|
1995 |
Emerich DF. CELL TRANSPLANTATION FOR HUNTINGTON'S DISEASE. Cell Transplantation. 4: 348-349. PMID 28148361 DOI: 10.1177/096368979500400315 |
0.347 |
|
1995 |
Hammang JP, Emerich DF, Winn SR, Lee A, Lindner MD, Gentile FT, Doherty EJ, Kordower JH, Baetge EE. Delivery of neurotrophic factors to the CNS using encapsulated cells: developing treatments for neurodegenerative diseases. Cell Transplantation. 4: S27-8. PMID 7795899 DOI: 10.1016/0963-6897(94)00069-V |
0.338 |
|
1995 |
Kordower JH, Liu YT, Winn S, Emerich DF. Encapsulated PC12 cell transplants into hemiparkinsonian monkeys: a behavioral, neuroanatomical, and neurochemical analysis. Cell Transplantation. 4: 155-71. PMID 7773555 DOI: 10.1016/0963-6897(95)90031-4 |
0.381 |
|
1995 |
Schinstine M, Fiore DM, Winn SR, Emerich DF. Polymer-encapsulated Schwannoma cells expressing human nerve growth factor promote the survival of cholinergic neurons after a fimbria-fornix transection. Cell Transplantation. 4: 93-102. PMID 7728338 DOI: 10.1016/0963-6897(94)00047-N |
0.385 |
|
1994 |
Winn SR, Hammang JP, Emerich DF, Lee A, Palmiter RD, Baetge EE. Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 2324-8. PMID 8134395 DOI: 10.1073/Pnas.91.6.2324 |
0.397 |
|
1994 |
Emerich DF, McDermott PE, Krueger PM, Winn SR. Intrastriatal implants of polymer-encapsulated PC12 cells: effects on motor function in aged rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 18: 935-46. PMID 7972863 DOI: 10.1016/0278-5846(94)90109-0 |
0.358 |
|
1994 |
Kordower JH, Winn SR, Liu YT, Mufson EJ, Sladek JR, Hammang JP, Baetge EE, Emerich DF. The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor. Proceedings of the National Academy of Sciences of the United States of America. 91: 10898-902. PMID 7971980 DOI: 10.1073/Pnas.91.23.10898 |
0.401 |
|
1994 |
Emerich DF, Winn SR, Harper J, Hammang JP, Baetge EE, Kordower JH. Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons. The Journal of Comparative Neurology. 349: 148-64. PMID 7852623 DOI: 10.1002/Cne.903490110 |
0.404 |
|
1994 |
Lysaght MJ, Frydel B, Gentile F, Emerich D, Winn S. Recent progress in immunoisolated cell therapy Journal of Cellular Biochemistry. 56: 196-203. PMID 7829581 DOI: 10.1002/Jcb.240560214 |
0.336 |
|
1994 |
Emerich DF, Hammang JP, Baetge EE, Winn SR. Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum. Experimental Neurology. 130: 141-50. PMID 7821389 DOI: 10.1006/exnr.1994.1193 |
0.432 |
|
1994 |
Flanagan TR, Frydel B, Tente B, Lavoie M, Doherty E, Rein D, Emerich DF, Winn SR. 24 – Tests for Validating the Safety of Encapsulated Xenografts Methods in Neurosciences. 21: 403-423. DOI: 10.1016/B978-0-12-185291-7.50030-8 |
0.346 |
|
1993 |
Emerich DF, Frydel BR, Flanagan TR, Palmatier M, Winn SR, Christenson L. TRANSPLANTATION OF POLYMER ENCAPSULATED PC12 CELLS: USE OF CHITOSAN AS AN IMMOBILIZATION MATRIX. Cell Transplantation. 2: 241-249. PMID 28148369 DOI: 10.1177/096368979300200308 |
0.367 |
|
1993 |
Walsh TJ, Stackman RW, Emerich DF, Taylor LA. Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus. Brain Research Bulletin. 31: 267-71. PMID 8387864 DOI: 10.1016/0361-9230(93)90216-X |
0.404 |
|
1993 |
Emerich DF, McDermott PE, Krueger PM, Frydel B, Sanberg PR, Winn SR. Polymer-encapsulated PC12 cells promote recovery of motor function in aged rats. Experimental Neurology. 122: 37-47. PMID 8339788 DOI: 10.1006/Exnr.1993.1105 |
0.37 |
|
1993 |
Emerich DF, McDermott P, Krueger P, Banks M, Zhao J, Marszalkowski J, Frydel B, Winn SR, Sanberg PR. Locomotion of aged rats: relationship to neurochemical but not morphological changes in nigrostriatal dopaminergic neurons. Brain Research Bulletin. 32: 477-86. PMID 8221140 DOI: 10.1016/0361-9230(93)90294-L |
0.316 |
|
1993 |
Lu SY, Pixley SK, Emerich DF, Lehman MN, Norman AB. Effect of fetal striatal and astrocyte transplants into unilateral excitotoxin-lesioned striatum. Journal of Neural Transplantation & Plasticity. 4: 279-87. PMID 7524691 DOI: 10.1155/NP.1993.279 |
0.359 |
|
1993 |
Sanberg PR, Emerich DF, Aebischer P, Amisetti SM, Ouellette W, Koutouzis TK, Cahill DW, Norman AB. Substance P containing polymer implants protect against striatal excitotoxicity. Brain Research. 628: 327-9. PMID 7508810 DOI: 10.1016/0006-8993(93)90974-R |
0.304 |
|
1992 |
Emerich DF, Black BA, Kesslak JP, Cotman CW, Walsh TJ. Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A. Brain Research Bulletin. 28: 219-26. PMID 1596741 DOI: 10.1016/0361-9230(92)90182-W |
0.512 |
|
1992 |
Christenson L, Emerich DF, Sanberg PR. Encapsulated cell implantation for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 7: 185-6. PMID 1584240 DOI: 10.1002/Mds.870070215 |
0.32 |
|
1992 |
Emerich DF. Behavioral effects of gangliosides: anatomical considerations. Journal of Neural Transplantation & Plasticity. 3: 1-19. PMID 1571395 DOI: 10.1155/NP.1992.1 |
0.323 |
|
1992 |
Emerich DF, Winn SR, Christenson L, Palmatier MA, Gentile FT, Sanberg PR. A novel approach to neural transplantation in Parkinson's disease: use of polymer-encapsulated cell therapy. Neuroscience and Biobehavioral Reviews. 16: 437-47. PMID 1480340 DOI: 10.1016/S0149-7634(05)80185-X |
0.386 |
|
1992 |
Emerich DF, Ragozzino M, Lehman MN, Sanberg PR. Behavioral effects of neural transplantation. Cell Transplantation. 1: 401-27. PMID 1344313 DOI: 10.1177/096368979200100604 |
0.348 |
|
1992 |
Emerich DF, Flanagan TR, Frydel BR, Gentile FT, Palmatier MA, Winn SR. Transplantation of encapsulated dopamine-secreting cells as a treatment for Parkinson's disease Journal of Neural Transplantation and Plasticity. 3: 267-268. DOI: 10.1155/Np.1992.267 |
0.348 |
|
1991 |
Emerich DF, Walsh TJ. Ganglioside AGF2 prevents the cognitive impairments and cholinergic cell loss following intraventricular colchicine. Experimental Neurology. 112: 328-37. PMID 2029933 DOI: 10.1016/0014-4886(91)90135-Y |
0.482 |
|
1991 |
Emerich DF, Zubricki EM, Shipley MT, Norman AB, Sanberg PR. Female rats are more sensitive to the locomotor alterations following quinolinic acid-induced striatal lesions: effects of striatal transplants. Experimental Neurology. 111: 369-78. PMID 1847880 DOI: 10.1016/0014-4886(91)90105-L |
0.348 |
|
1990 |
Emerich DF, Walsh TJ. Cholinergic cell loss and cognitive impairments following intraventricular or intradentate injection of colchicine. Brain Research. 517: 157-67. PMID 2375986 DOI: 10.1016/0006-8993(90)91021-8 |
0.487 |
|
1990 |
Sanberg PR, Emerich DF. Neural basis of behavior: animal models of human conditions. Brain Research Bulletin. 25: 447-51. PMID 2292044 DOI: 10.1016/0361-9230(90)90237-T |
0.32 |
|
1990 |
Emerich DF, Walsh TJ. Ganglioside AGF2 promotes task-specific recovery and attenuates the cholinergic hypofunction induced by AF64A. Brain Research. 527: 299-307. PMID 2253037 DOI: 10.1016/0006-8993(90)91150-F |
0.464 |
|
1990 |
Emerich DF, Walsh TJ. Hyperactivity following intradentate injection of colchicine: a role for dopamine systems in the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 37: 149-54. PMID 2124711 DOI: 10.1016/0091-3057(90)90055-M |
0.477 |
|
1990 |
Walsh TJ, Emerich DF. Cholinotoxic effects of intraventricular colchicine: A new model of cholinergic hypofunction European Journal of Pharmacology. 183: 1928. DOI: 10.1016/0014-2999(90)92274-M |
0.32 |
|
1989 |
Walsh TJ, Emerich DF, Schmechel DE. GM1 ganglioside attenuates the behavioral deficits but not the granule cell damage produced by intradentate colchicine. Brain Research. 478: 24-33. PMID 2924118 DOI: 10.1016/0006-8993(89)91473-X |
0.502 |
|
1989 |
Walsh TJ, Emerich DF, Bondy SC. Destruction of specific hippocampal cell fields increases ornithine decarboxylase activity: modulation of the biochemical but not the histological changes by ganglioside GM1. Experimental Neurology. 105: 54-61. PMID 2744127 DOI: 10.1016/0014-4886(89)90171-4 |
0.466 |
|
1989 |
Emerich DF, Walsh TJ. Selective working memory impairments following intradentate injection of colchicine: attenuation of the behavioral but not the neuropathological effects by gangliosides GM1 and AGF2. Physiology & Behavior. 45: 93-101. PMID 2727146 DOI: 10.1016/0031-9384(89)90170-4 |
0.47 |
|
1989 |
Flaherty CF, Rowan GA, Emerich DF, Walsh TJ. Effects of intrahippocampal administration of colchicine on incentive contrast and on radial maze performance. Behavioral Neuroscience. 103: 319-28. PMID 2706077 DOI: 10.1037/0735-7044.103.2.319 |
0.455 |
|
1988 |
Walsh TJ, Emerich DF. The hippocampus as a common target of neurotoxic agents. Toxicology. 49: 137-40. PMID 3287689 DOI: 10.1016/0300-483X(88)90185-0 |
0.437 |
|
1986 |
Tilson HA, Emerich D, Bondy SC. Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen Brain Research. 379: 147-150. PMID 2427159 DOI: 10.1016/0006-8993(86)90267-2 |
0.314 |
|
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