Dwaine F. Emerich - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
stem cells, encapsulated therapeutics, recovery of function

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Year Citation  Score
2020 Wahlberg LU, Emerich DF, Kordower JH, Bell W, Fradet T, Paolone G. Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain. Current Research in Pharmacology and Drug Discovery. 1: 19-29. PMID 34909639 DOI: 10.1016/j.crphar.2020.04.001  0.304
2019 Orive G, Echave MC, Pedraz JL, Golafshan N, Dolatshahi-Pirouz A, Paolone G, Emerich D. Advances in cell-laden hydrogels for delivering therapeutics. Expert Opinion On Biological Therapy. 1-4. PMID 31414944 DOI: 10.1080/14712598.2019.1654452  0.324
2019 Emerich DF, Kordower JH, Chu Y, Thanos C, Bintz B, Paolone G, Wahlberg LU. Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity. Neural Plasticity. 2019: 6286197. PMID 30984255 DOI: 10.1155/2019/6286197  0.403
2019 Paolone G, Falcicchia C, Lovisari F, Kokaia M, Bell WJ, Fradet T, Barbieri M, Wahlberg LU, Emerich DF, Simonato M. Long-term, targeted delivery of GDNF from encapsulated cells is neuroprotective and reduces seizures in the pilocarpine model of epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30665947 DOI: 10.1523/JNEUROSCI.0435-18.2018  0.332
2018 Orive G, Santos-Vizcaino E, Pedraz JL, Hernandez RM, Vela Ramirez JE, Dolatshahi-Pirouz A, Khademhosseini A, Peppas NA, Emerich DF. 3D cell-laden polymers to release bioactive products in the eye. Progress in Retinal and Eye Research. PMID 30342088 DOI: 10.1016/J.Preteyeres.2018.10.002  0.312
2018 Savolainen M, Emerich D, Kordower JH. Disease Modification Through Trophic Factor Delivery. Methods in Molecular Biology (Clifton, N.J.). 1780: 525-547. PMID 29856034 DOI: 10.1007/978-1-4939-7825-0_24  0.364
2018 Falcicchia C, Paolone G, Emerich DF, Lovisari F, Bell WJ, Fradet T, Wahlberg LU, Simonato M. Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy. Molecular Therapy. Methods & Clinical Development. 9: 211-224. PMID 29766029 DOI: 10.1016/j.omtm.2018.03.001  0.329
2018 Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P. Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes. Trends in Biotechnology. PMID 29455936 DOI: 10.1016/J.Tibtech.2018.01.007  0.335
2017 Sandrof MA, Emerich DF, Thanos CG. Primary Choroid Plexus Tissue for Use in Cellular Therapy. Methods in Molecular Biology (Clifton, N.J.). 1479: 237-249. PMID 27738941 DOI: 10.1007/978-1-4939-6364-5_19  0.345
2015 Orive G, Santos E, Poncelet D, Hernández RM, Pedraz JL, Wahlberg LU, De Vos P, Emerich D. Cell encapsulation: technical and clinical advances. Trends in Pharmacological Sciences. PMID 26067102 DOI: 10.1016/J.Tips.2015.05.003  0.333
2014 Emerich DF, Orive G, Thanos C, Tornoe J, Wahlberg LU. Encapsulated cell therapy for neurodegenerative diseases: from promise to product. Advanced Drug Delivery Reviews. 67: 131-41. PMID 23880505 DOI: 10.1016/J.Addr.2013.07.008  0.377
2012 Tornøe J, Torp M, Jørgensen JR, Emerich DF, Thanos C, Bintz B, Fjord-Larsen L, Wahlberg LU. Encapsulated cell-based biodelivery of meteorin is neuroprotective in the quinolinic acid rat model of neurodegenerative disease. Restorative Neurology and Neuroscience. 30: 225-36. PMID 22426041 DOI: 10.3233/RNN-2012-110199  0.416
2012 Zanin MP, Pettingill LN, Harvey AR, Emerich DF, Thanos CG, Shepherd RK. The development of encapsulated cell technologies as therapies for neurological and sensory diseases. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 3-13. PMID 22285549 DOI: 10.1016/J.Jconrel.2012.01.021  0.384
2012 Fjord-Larsen L, Kusk P, Emerich DF, Thanos C, Torp M, Bintz B, Tornøe J, Johnsen AH, Wahlberg LU. Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer. Gene Therapy. 19: 1010-7. PMID 22113314 DOI: 10.1038/gt.2011.178  0.369
2011 Ali OA, Doherty E, Bell WJ, Fradet T, Hudak J, Laliberte MT, Mooney DJ, Emerich DF. The efficacy of intracranial PLG-based vaccines is dependent on direct implantation into brain tissue. Journal of Controlled Release : Official Journal of the Controlled Release Society. 154: 249-57. PMID 21704093 DOI: 10.1016/J.Jconrel.2011.06.021  0.306
2011 Emerich DF, Orive G, Borlongan C. Tales of biomaterials, molecules, and cells for repairing and treating brain dysfunction. Current Stem Cell Research & Therapy. 6: 171-89. PMID 21476979 DOI: 10.2174/157488811796575350  0.364
2011 Thanos CG, Bintz BE, Goddard M, Boekelheide K, Hall S, Emerich DF. Functional modulation of choroid plexus epithelial clusters in vitro for tissue repair applications. Cell Transplantation. 20: 1659-72. PMID 21396169 DOI: 10.3727/096368911X564985  0.332
2011 Jørgensen JR, Emerich DF, Thanos C, Thompson LH, Torp M, Bintz B, Fjord-Larsen L, Johansen TE, Wahlberg LU. Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model. Neurobiology of Disease. 41: 160-8. PMID 20840868 DOI: 10.1016/j.nbd.2010.09.003  0.407
2010 Emerich DF, Silva E, Ali O, Mooney D, Bell W, Yu SJ, Kaneko Y, Borlongan C. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplantation. 19: 1063-71. PMID 20412616 DOI: 10.3727/096368910X498278  0.313
2010 Thanos CG, Bintz B, Emerich DF. Microencapsulated choroid plexus epithelial cell transplants for repair of the brain. Advances in Experimental Medicine and Biology. 670: 80-91. PMID 20384220 DOI: 10.1007/978-1-4419-5786-3_8  0.348
2010 Emerich DF, Mooney DJ, Storrie H, Babu RS, Kordower JH. Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease. Neurotoxicity Research. 17: 66-74. PMID 19588214 DOI: 10.1007/S12640-009-9079-0  0.374
2009 Thanos CG, Emerich DF, Bintz BE, Goddard M, Mills J, Jensen R, Lombardi M, Hall S, Boekelheide K. Secreted products from the porcine choroid plexus accelerate the healing of cutaneous wounds. Cell Transplantation. 18: 1395-409. PMID 19660181 DOI: 10.3727/096368909X12483162197402  0.326
2009 Emerich DF, Borlongan CV. Potential of choroid plexus epithelial cell grafts for neuroprotection in Huntington's disease: what remains before considering clinical trials. Neurotoxicity Research. 15: 205-11. PMID 19384593 DOI: 10.1007/s12640-009-9021-5  0.39
2008 Emerich DF, Thanos CG, Sanberg PR. Intraventricular implant of encapsulated CNTF-secreting fibroblasts ameliorates motor deficits in aged rats. Current Aging Science. 1: 105-11. PMID 20021379 DOI: 10.2174/1874609810801020105  0.323
2008 Thanos CG, Emerich DF. On the use of hydrogels in cell encapsulation and tissue engineering system. Recent Patents On Drug Delivery & Formulation. 2: 19-24. PMID 19075894 DOI: 10.2174/187221108783331384  0.315
2008 Borlongan CV, Thanos CG, Skinner SJ, Geaney M, Emerich DF. Transplants of encapsulated rat choroid plexus cells exert neuroprotection in a rodent model of Huntington's disease. Cell Transplantation. 16: 987-92. PMID 18351014 DOI: 10.3727/000000007783472426  0.307
2007 Borlongan CV, Thanos CG, Skinner SJM, Geaney M, Emerich DF. Transplants of Encapsulated Rat Choroid Plexus Cells Exert Neuroprotection in a Rodent Model of Huntington's Disease. Cell Transplantation. 16: 987-992. PMID 28866919 DOI: 10.3727/000000007783472426  0.417
2007 Borlongan CV, Masuda T, Walker TA, Maki M, Hara K, Yasuhara T, Matsukawa N, Emerich DF. Nanotechnology as an adjunct tool for transplanting engineered cells and tissues. Current Molecular Medicine. 7: 609-18. PMID 18045140 DOI: 10.2174/156652407782564381  0.381
2007 Emerich DF, Schneider P, Bintz B, Hudak J, Thanos CG. Aging reduces the neuroprotective capacity, VEGF secretion, and metabolic activity of rat choroid plexus epithelial cells. Cell Transplantation. 16: 697-705. PMID 18019359 DOI: 10.3727/000000007783465145  0.425
2007 Emerich DF, Schneider P, Bintz B, Hudak J, Thanos CG. In vitro exposure of cultured porcine choroid plexus epithelial cells to immunosuppressant, anti-inflammatory, and psychoactive drugs. Cell Transplantation. 16: 435-40. PMID 17658133 DOI: 10.3727/000000007783464867  0.395
2006 Emerich DF, Thanos CG. In vitro culture duration does not impact the ability of encapsulated choroid plexus transplants to prevent neurological deficits in an excitotoxin-lesioned rat model of Huntington's disease. Cell Transplantation. 15: 595-602. PMID 17176611 DOI: 10.3727/000000006783981657  0.437
2006 Halberstadt C, Emerich DF, Gonsalves K. Combining cell therapy and nanotechnology. Expert Opinion On Biological Therapy. 6: 971-81. PMID 16989579 DOI: 10.1517/14712598.6.10.971  0.379
2006 Emerich DF, Thanos CG, Goddard M, Skinner SJ, Geany MS, Bell WJ, Bintz B, Schneider P, Chu Y, Babu RS, Borlongan CV, Boekelheide K, Hall S, Bryant B, Kordower JH. Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys. Neurobiology of Disease. 23: 471-80. PMID 16777422 DOI: 10.1016/J.Nbd.2006.04.014  0.393
2006 Skinner SJ, Geaney MS, Rush R, Rogers ML, Emerich DF, Thanos CG, Vasconcellos AV, Tan PL, Elliott RB. Choroid plexus transplants in the treatment of brain diseases. Xenotransplantation. 13: 284-8. PMID 16768721 DOI: 10.1111/J.1399-3089.2006.00310.X  0.396
2006 Emerich DF, Thanos CG. Intracompartmental delivery of CNTF as therapy for Huntington's disease and retinitis pigmentosa. Current Gene Therapy. 6: 147-59. PMID 16475952 DOI: 10.2174/156652306775515547  0.391
2005 Emerich DF, Skinner SJ, Borlongan CV, Thanos CG. A role of the choroid plexus in transplantation therapy. Cell Transplantation. 14: 715-25. PMID 16454346 DOI: 10.3727/000000005783982576  0.347
2005 Halberstadt CR, Williams D, Emerich D, Goddard M, Vasconcellos AV, Curry W, Bhatia A, Gores PF. Subcutaneous transplantation of islets into streptozocin-induced diabetic rats. Cell Transplantation. 14: 595-605. PMID 16355568 DOI: 10.3727/000000005783982792  0.335
2005 Thanos C, Emerich D. Delivery of neurotrophic factors and therapeutic proteins for retinal diseases Expert Opinion On Biological Therapy. 5: 1443-1452. PMID 16255648 DOI: 10.1517/14712598.5.11.1443  0.352
2005 Hemendinger R, Wang J, Malik S, Persinski R, Copeland J, Emerich D, Gores P, Halberstadt C, Rosenfeld J. Sertoli cells improve survival of motor neurons in SOD1 transgenic mice, a model of amyotrophic lateral sclerosis. Experimental Neurology. 196: 235-43. PMID 16242126 DOI: 10.1016/J.Expneurol.2005.07.025  0.368
2005 Emerich DF, Skinner SJ, Borlongan CV, Vasconcellos AV, Thanos CG. The choroid plexus in the rise, fall and repair of the brain. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 27: 262-74. PMID 15714561 DOI: 10.1002/bies.20193  0.33
2004 Newman MB, Emerich DF, Borlongan CV, Sanberg CD, Sanberg PR. Use of human umbilical cord blood (HUCB) cells to repair the damaged brain. Current Neurovascular Research. 1: 269-81. PMID 16181077 DOI: 10.2174/1567202043362261  0.35
2004 Emerich DF. Dose-dependent neurochemical and functional protection afforded by encapsulated CNTF-producing cells. Cell Transplantation. 13: 839-44. PMID 15690987 DOI: 10.3727/000000004783983404  0.333
2004 Emerich DF. The convergence of cell transplantation and nanoengineering. Cell Transplantation. 13: 477-9. PMID 15565859 DOI: 10.3727/000000004783983657  0.329
2004 Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. Neuroprotection by encapsulated choroid plexus in a rodent model of Huntington's disease. Neuroreport. 15: 2521-5. PMID 15538187 DOI: 10.1097/00001756-200411150-00018  0.411
2004 Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke. Stroke; a Journal of Cerebral Circulation. 35: 2206-10. PMID 15284450 DOI: 10.1161/01.STR.0000138954.25825.0b  0.376
2004 Borlongan CV, Emerich DF. Eleventh Annual Conference of the American Society for Neural Transplantation and Repair. Expert Opinion On Biological Therapy. 4: 1351-5. PMID 15268668 DOI: 10.1517/14712598.4.8.1351  0.331
2004 Emerich DF, Vasconcellos AV, Elliott RB, Skinner SJ, Borlongan CV. The choroid plexus: function, pathology and therapeutic potential of its transplantation. Expert Opinion On Biological Therapy. 4: 1191-201. PMID 15268655 DOI: 10.1517/14712598.4.8.1191  0.358
2004 Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. CNS grafts of rat choroid plexus protect against cerebral ischemia in adult rats. Neuroreport. 15: 1543-7. PMID 15232280 DOI: 10.1097/01.wnr.0000133298.84901.cf  0.367
2004 Emerich DF, Winn SR. Neuroprotective effects of encapsulated CNTF-producing cells in a rodent model of Huntington's disease are dependent on the proximity of the implant to the lesioned striatum. Cell Transplantation. 13: 253-9. PMID 15191163 DOI: 10.3727/000000004783983981  0.415
2004 Halberstadt C, Emerich DF, Gores P. Use of Sertoli cell transplants to provide local immunoprotection for tissue grafts. Expert Opinion On Biological Therapy. 4: 813-25. PMID 15174964 DOI: 10.1517/14712598.4.6.813  0.382
2004 Emerich DF. Sertoli cell grafts for Huntington's disease. An opinion. Neurotoxicity Research. 5: 567. PMID 15111233 DOI: 10.1007/BF03033176  0.363
2004 Dufour JM, Gores P, Hemendinger R, Emerich DF, Halberstadt CR. Transgenic Sertoli cells as a vehicle for gene therapy. Cell Transplantation. 13: 1-6. PMID 15040599 DOI: 10.3727/000000004772664833  0.314
2004 Newman MB, Davis CD, Borlongan CV, Emerich D, Sanberg PR. Transplantation of human umbilical cord blood cells in the repair of CNS diseases. Expert Opinion On Biological Therapy. 4: 121-30. PMID 14998772 DOI: 10.1517/14712598.4.2.121  0.389
2004 Dufour JM, Hemendinger R, Halberstadt CR, Gores P, Emerich DF, Korbutt GS, Rajotte RV. Genetically engineered Sertoli cells are able to survive allogeneic transplantation. Gene Therapy. 11: 694-700. PMID 14724669 DOI: 10.1038/sj.gt.3302218  0.326
2003 Emerich DF, Hemendinger R, Halberstadt CR. The testicular-derived Sertoli cell: cellular immunoscience to enable transplantation. Cell Transplantation. 12: 335-49. PMID 12911122 DOI: 10.3727/000000003108746894  0.384
2003 Blanchet PJ, Konitsiotis S, Mochizuki H, Pluta R, Emerich DF, Chase TN, Mouradian MM. Complications of a trophic xenotransplant approach in parkinsonian monkeys. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 607-12. PMID 12787846 DOI: 10.1016/S0278-5846(03)00048-4  0.423
2003 Borlongan CV, Emerich DF. Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport. Brain Research Bulletin. 60: 297-306. PMID 12754091 DOI: 10.1016/S0361-9230(03)00043-1  0.323
2003 Salzberg-Brenhouse HC, Chen EY, Emerich DF, Baldwin S, Hogeland K, Ranelli S, Lafreniere D, Perdomo B, Novak L, Kladis T, Fu K, Basile AS, Kordower JH, Bartus RT. Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. The Journal of Pharmacology and Experimental Therapeutics. 306: 218-28. PMID 12676885 DOI: 10.1124/Jpet.103.049700  0.308
2002 Emerich DF. Islet transplantation for diabetes: current status and future prospects. Expert Opinion On Biological Therapy. 2: 793-803. PMID 12517259 DOI: 10.1517/14712598.2.8.793  0.34
2002 Borlongan CV, Emerich DF, Hoffer BJ, Bartus RT. Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6-hydroxydopamine neurotoxicity. Brain Research. 956: 211-20. PMID 12445688 DOI: 10.1016/S0006-8993(02)03474-1  0.328
2002 Emerich DF, Sanberg PR. Novel means to selectively identify Sertoli cell transplants. Cell Transplantation. 11: 495-7. PMID 12428737 DOI: 10.3727/000000002783985594  0.326
2002 Emerich DF, Winn SR, Bartus RT. Injection of chemotherapeutic microspheres and glioma. IV: Eradicating tumors in rats. Cell Transplantation. 11: 47-54. PMID 12095219 DOI: 10.3727/096020198389771  0.346
2002 Emerich DF, Winn SR, Bartus RT. Injection of chemotherapeutic microspheres and glioma. III: Parameters to optimize efficacy. Cell Transplantation. 11: 35-45. PMID 12095218 DOI: 10.3727/096020198389762  0.317
2002 Emerich DF, Dean RL, Bartus RT. The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct? Experimental Neurology. 173: 168-81. PMID 11771949 DOI: 10.1006/exnr.2001.7835  0.317
2001 Emerich DF. Neuroprotective possibilities for Huntington's disease. Expert Opinion On Biological Therapy. 1: 467-79. PMID 11727519 DOI: 10.1517/14712598.1.3.467  0.307
2001 Emerich DF, Winn SR. Immunoisolation cell therapy for CNS diseases. Critical Reviews in Therapeutic Drug Carrier Systems. 18: 265-98. PMID 11442201 DOI: 10.1615/Critrevtherdrugcarriersyst.V18.I3.10  0.359
2001 Emerich DF, Salzberg HC. Update on immunoisolation cell therapy for CNS diseases. Cell Transplantation. 10: 3-24. PMID 11294469 DOI: 10.3727/000000001783986981  0.374
2001 Emerich DF, Dean RL, Osborn C, Bartus RT. The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation. Clinical Pharmacokinetics. 40: 105-23. PMID 11286321 DOI: 10.2165/00003088-200140020-00003  0.318
2000 Emerich DF, Dean RL, Marsh J, Pink M, Lafreniere D, Snodgrass P, Bartus RT. Intravenous cereport (RMP-7) enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain. Pharmaceutical Research. 17: 1212-9. PMID 11145226 DOI: 10.1023/A:1026462629438  0.318
2000 Lindner MD, Francis JM, Plone MA, McDermott PE, Frydel BR, Emerich DF, Saydoff JA. The analgesic potential of intraventricular polymer-encapsulated adrenal chromaffin cells in a rodent model of chronic neuropathic pain. Experimental and Clinical Psychopharmacology. 8: 524-38. PMID 11127424 DOI: 10.1037//1064-1297.8.4.524  0.31
2000 Emerich DF, Winn SR, Snodgrass P, LaFreniere D, Agostino M, Wiens T, Xiong H, Bartus RT. Injectable chemotherapeutic microspheres and glioma II: enhanced survival following implantation into deep inoperable tumors. Pharmaceutical Research. 17: 776-81. PMID 10990194 DOI: 10.1023/A:1007591721877  0.301
2000 Emerich DF, Winn SR, Hu Y, Marsh J, Snodgrass P, LaFreniere D, Wiens T, Hasler BP, Bartus RT. Injectable chemotherapeutic microspheres and glioma I: enhanced survival following implantation into the cavity wall of debulked tumors. Pharmaceutical Research. 17: 767-75. PMID 10990193 DOI: 10.1023/A:1007576405039  0.339
1999 Dean RL, Emerich DF, Hasler BP, Bartus RT. Cereport (RMP-7) increases carboplatin levels in brain tumors after pretreatment with dexamethasone. Neuro-Oncology. 1: 268-74. PMID 11550318 DOI: 10.1093/Neuonc/1.4.268  0.303
1999 Emerich DF. Encapsulated CNTF-producing cells for Huntington's disease. Cell Transplantation. 8: 581-2. PMID 10701486 DOI: 10.1177/096368979900800603  0.317
1999 Kordower JH, Isacson O, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Experimental Neurology. 159: 4-20. PMID 10486171 DOI: 10.1006/Exnr.1999.7156  0.358
1999 Lindner MD, Cain CK, Plone MA, Frydel BR, Blaney TJ, Emerich DF, Hoane MR. Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats. Behavioural Brain Research. 102: 1-16. PMID 10403011 DOI: 10.1016/S0166-4328(98)00160-0  0.339
1999 Emerich DF, Snodgrass P, Dean R, Agostino M, Hasler B, Pink M, Xiong H, Kim BS, Bartus RT. Enhanced delivery of carboplatin into brain tumours with intravenous Cereport (RMP-7): dramatic differences and insight gained from dosing parameters. British Journal of Cancer. 80: 964-70. PMID 10362103 DOI: 10.1038/Sj.Bjc.6690450  0.308
1999 Emerich DF, Tracy MA, Ward KL, Figueiredo M, Qian R, Henschel C, Bartus RT. Biocompatibility of poly (DL-lactide-co-glycolide) microspheres implanted into the brain. Cell Transplantation. 8: 47-58. PMID 10338275 DOI: 10.1177/096368979900800114  0.333
1998 Emerich DF, Snodgrass P, Pink M, Bloom F, Bartus RT. Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport (RMP-7). Brain Research. 801: 259-66. PMID 9729419 DOI: 10.1016/S0006-8993(98)00571-X  0.325
1998 Emerich DF, Bruhn S, Chu Y, Kordower JH. Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease. Cell Transplantation. 7: 213-25. PMID 9588602 DOI: 10.1016/S0963-6897(97)00163-2  0.416
1998 Lindner MD, Emerich DF. Therapeutic potential of a polymer-encapsulated L-DOPA and dopamine-producing cell line in rodent and primate models of Parkinson's disease. Cell Transplantation. 7: 165-74. PMID 9588598 DOI: 10.1016/S0963-6897(97)00169-3  0.373
1998 Lindner MD, Plone MA, Cain CK, Frydel B, Francis JM, Emerich DF, Sutton RL. Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions. Journal of Neurotrauma. 15: 199-216. PMID 9528920 DOI: 10.1089/Neu.1998.15.199  0.305
1997 Lindner MD, Plone MA, Frydel B, Kaplan FA, Krueger PM, Bell WJ, Blaney TJ, Winn SR, Sherman SS, Doherty EJ, Emerich DF. Intraventricular encapsulated calf adrenal chromaffin cells: viable for at least 500 days in vivo without detectable adverse effects on behavioral/cognitive function or host immune sensitization in rats. Restorative Neurology and Neuroscience. 11: 21-35. PMID 21551525 DOI: 10.3233/RNN-1997-111203  0.405
1997 Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP. Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice. Experimental Neurology. 148: 187-204. PMID 9398461 DOI: 10.1006/Exnr.1997.6657  0.395
1997 Subramanian T, Emerich DF, Bakay RA, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates. Cell Transplantation. 6: 469-77. PMID 9331498 DOI: 10.1016/S0963-6897(97)00049-3  0.326
1997 Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK. Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease. The Journal of Comparative Neurology. 387: 96-113. PMID 9331174 DOI: 10.1002/(Sici)1096-9861(19971013)387:1<96::Aid-Cne8>3.0.Co;2-I  0.414
1997 Date I, Shingo T, Ohmoto T, Emerich DF. Long-term enhanced chromaffin cell survival and behavioral recovery in hemiparkinsonian rats with co-grafted polymer-encapsulated human NGF-secreting cells. Experimental Neurology. 147: 10-7. PMID 9294398 DOI: 10.1006/exnr.1997.6579  0.414
1997 Lindner MD, Plone MA, Mullins TD, Winn SR, Chandonait SE, Stott JA, Blaney TJ, Sherman SS, Emerich DF. Somatic delivery of catecholamines in the striatum attenuate parkinsonian symptoms and widen the therapeutic window of oral sinemet in rats. Experimental Neurology. 145: 130-40. PMID 9184116 DOI: 10.1006/exnr.1997.6456  0.356
1997 Emerich DF, Cain CK, Greco C, Saydoff JA, Hu ZY, Liu H, Lindner MD. Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease. Cell Transplantation. 6: 249-66. PMID 9171158 DOI: 10.1016/S0963-6897(97)00035-3  0.438
1997 Emerich DF, Winn SR, Hantraye PM, Peschanski M, Chen EY, Chu Y, McDermott P, Baetge EE, Kordower JH. Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature. 386: 395-9. PMID 9121555 DOI: 10.1038/386395A0  0.367
1997 Lindner MD, Plone MA, Francis JM, Blaney TJ, Salamone JD, Emerich DF. Rats with partial striatal dopamine depletions exhibit robust and long-lasting behavioral deficits in a simple fixed-ratio bar-pressing task. Behavioural Brain Research. 86: 25-40. PMID 9105579 DOI: 10.1016/S0166-4328(96)02240-1  0.321
1996 Lindner MD, Plone MA, Francis JM, Emerich DF. Validation of a rodent model of Parkinson's Disease: evidence of a therapeutic window for oral Sinemet. Brain Research Bulletin. 39: 367-72. PMID 9138746 DOI: 10.1016/0361-9230(96)00027-5  0.334
1996 Date I, Ohmoto T, Imaoka T, Shingo T, Emerich DF. Chromaffin cell survival from both young and old donors is enhanced by co-grafts of polymer-encapsulated human NGF-secreting cells. Neuroreport. 7: 1813-8. PMID 8905671 DOI: 10.1097/00001756-199607290-00025  0.404
1996 Emerich DF, Winn SR, Lindner MD. Continued presence of intrastriatal but not intraventricular polymer-encapsulated PC12 cells is required for alleviation of behavioral deficits in Parkinsonian rodents. Cell Transplantation. 5: 589-96. PMID 8889217 DOI: 10.1016/0963-6897(96)00086-3  0.369
1996 Date I, Ohmoto T, Imaoka T, Ono T, Hammang JP, Francis J, Greco C, Emerich DF. Cografting with polymer-encapsulated human nerve growth factor-secreting cells and chromaffin cell survival and behavioral recovery in hemiparkinsonian rats. Journal of Neurosurgery. 84: 1006-12. PMID 8847564 DOI: 10.3171/jns.1996.84.6.1006  0.428
1996 Emerich DF, Lindner MD, Winn SR, Chen EY, Frydel BR, Kordower JH. Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5168-81. PMID 8756445 DOI: 10.1523/Jneurosci.16-16-05168.1996  0.452
1996 Winn SR, Lindner MD, Lee A, Haggett G, Francis JM, Emerich DF. Polymer-encapsulated genetically modified cells continue to secrete human nerve growth factor for over one year in rat ventricles: behavioral and anatomical consequences. Experimental Neurology. 140: 126-38. PMID 8690056 DOI: 10.1006/exnr.1996.0123  0.417
1996 Lindner MD, Kearns CE, Winn SR, Frydel B, Emerich DF. Effects of intraventricular encapsulated hNGF-secreting fibroblasts in aged rats. Cell Transplantation. 5: 205-23. PMID 8689032 DOI: 10.1016/0963-6897(95)02029-2  0.355
1995 Emerich DF. CELL TRANSPLANTATION FOR HUNTINGTON'S DISEASE. Cell Transplantation. 4: 348-349. PMID 28148361 DOI: 10.1177/096368979500400315  0.347
1995 Hammang JP, Emerich DF, Winn SR, Lee A, Lindner MD, Gentile FT, Doherty EJ, Kordower JH, Baetge EE. Delivery of neurotrophic factors to the CNS using encapsulated cells: developing treatments for neurodegenerative diseases. Cell Transplantation. 4: S27-8. PMID 7795899 DOI: 10.1016/0963-6897(94)00069-V  0.338
1995 Kordower JH, Liu YT, Winn S, Emerich DF. Encapsulated PC12 cell transplants into hemiparkinsonian monkeys: a behavioral, neuroanatomical, and neurochemical analysis. Cell Transplantation. 4: 155-71. PMID 7773555 DOI: 10.1016/0963-6897(95)90031-4  0.381
1995 Schinstine M, Fiore DM, Winn SR, Emerich DF. Polymer-encapsulated Schwannoma cells expressing human nerve growth factor promote the survival of cholinergic neurons after a fimbria-fornix transection. Cell Transplantation. 4: 93-102. PMID 7728338 DOI: 10.1016/0963-6897(94)00047-N  0.385
1994 Winn SR, Hammang JP, Emerich DF, Lee A, Palmiter RD, Baetge EE. Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 2324-8. PMID 8134395 DOI: 10.1073/Pnas.91.6.2324  0.397
1994 Emerich DF, McDermott PE, Krueger PM, Winn SR. Intrastriatal implants of polymer-encapsulated PC12 cells: effects on motor function in aged rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 18: 935-46. PMID 7972863 DOI: 10.1016/0278-5846(94)90109-0  0.358
1994 Kordower JH, Winn SR, Liu YT, Mufson EJ, Sladek JR, Hammang JP, Baetge EE, Emerich DF. The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor. Proceedings of the National Academy of Sciences of the United States of America. 91: 10898-902. PMID 7971980 DOI: 10.1073/Pnas.91.23.10898  0.401
1994 Emerich DF, Winn SR, Harper J, Hammang JP, Baetge EE, Kordower JH. Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons. The Journal of Comparative Neurology. 349: 148-64. PMID 7852623 DOI: 10.1002/Cne.903490110  0.404
1994 Lysaght MJ, Frydel B, Gentile F, Emerich D, Winn S. Recent progress in immunoisolated cell therapy Journal of Cellular Biochemistry. 56: 196-203. PMID 7829581 DOI: 10.1002/Jcb.240560214  0.336
1994 Emerich DF, Hammang JP, Baetge EE, Winn SR. Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum. Experimental Neurology. 130: 141-50. PMID 7821389 DOI: 10.1006/exnr.1994.1193  0.432
1994 Flanagan TR, Frydel B, Tente B, Lavoie M, Doherty E, Rein D, Emerich DF, Winn SR. 24 – Tests for Validating the Safety of Encapsulated Xenografts Methods in Neurosciences. 21: 403-423. DOI: 10.1016/B978-0-12-185291-7.50030-8  0.346
1993 Emerich DF, Frydel BR, Flanagan TR, Palmatier M, Winn SR, Christenson L. TRANSPLANTATION OF POLYMER ENCAPSULATED PC12 CELLS: USE OF CHITOSAN AS AN IMMOBILIZATION MATRIX. Cell Transplantation. 2: 241-249. PMID 28148369 DOI: 10.1177/096368979300200308  0.367
1993 Walsh TJ, Stackman RW, Emerich DF, Taylor LA. Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus. Brain Research Bulletin. 31: 267-71. PMID 8387864 DOI: 10.1016/0361-9230(93)90216-X  0.404
1993 Emerich DF, McDermott PE, Krueger PM, Frydel B, Sanberg PR, Winn SR. Polymer-encapsulated PC12 cells promote recovery of motor function in aged rats. Experimental Neurology. 122: 37-47. PMID 8339788 DOI: 10.1006/Exnr.1993.1105  0.37
1993 Emerich DF, McDermott P, Krueger P, Banks M, Zhao J, Marszalkowski J, Frydel B, Winn SR, Sanberg PR. Locomotion of aged rats: relationship to neurochemical but not morphological changes in nigrostriatal dopaminergic neurons. Brain Research Bulletin. 32: 477-86. PMID 8221140 DOI: 10.1016/0361-9230(93)90294-L  0.316
1993 Lu SY, Pixley SK, Emerich DF, Lehman MN, Norman AB. Effect of fetal striatal and astrocyte transplants into unilateral excitotoxin-lesioned striatum. Journal of Neural Transplantation & Plasticity. 4: 279-87. PMID 7524691 DOI: 10.1155/NP.1993.279  0.359
1993 Sanberg PR, Emerich DF, Aebischer P, Amisetti SM, Ouellette W, Koutouzis TK, Cahill DW, Norman AB. Substance P containing polymer implants protect against striatal excitotoxicity. Brain Research. 628: 327-9. PMID 7508810 DOI: 10.1016/0006-8993(93)90974-R  0.304
1992 Emerich DF, Black BA, Kesslak JP, Cotman CW, Walsh TJ. Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A. Brain Research Bulletin. 28: 219-26. PMID 1596741 DOI: 10.1016/0361-9230(92)90182-W  0.513
1992 Christenson L, Emerich DF, Sanberg PR. Encapsulated cell implantation for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 7: 185-6. PMID 1584240 DOI: 10.1002/Mds.870070215  0.32
1992 Emerich DF. Behavioral effects of gangliosides: anatomical considerations. Journal of Neural Transplantation & Plasticity. 3: 1-19. PMID 1571395 DOI: 10.1155/NP.1992.1  0.323
1992 Emerich DF, Winn SR, Christenson L, Palmatier MA, Gentile FT, Sanberg PR. A novel approach to neural transplantation in Parkinson's disease: use of polymer-encapsulated cell therapy. Neuroscience and Biobehavioral Reviews. 16: 437-47. PMID 1480340 DOI: 10.1016/S0149-7634(05)80185-X  0.386
1992 Emerich DF, Ragozzino M, Lehman MN, Sanberg PR. Behavioral effects of neural transplantation. Cell Transplantation. 1: 401-27. PMID 1344313 DOI: 10.1177/096368979200100604  0.348
1992 Emerich DF, Flanagan TR, Frydel BR, Gentile FT, Palmatier MA, Winn SR. Transplantation of encapsulated dopamine-secreting cells as a treatment for Parkinson's disease Journal of Neural Transplantation and Plasticity. 3: 267-268. DOI: 10.1155/Np.1992.267  0.348
1991 Emerich DF, Walsh TJ. Ganglioside AGF2 prevents the cognitive impairments and cholinergic cell loss following intraventricular colchicine. Experimental Neurology. 112: 328-37. PMID 2029933 DOI: 10.1016/0014-4886(91)90135-Y  0.483
1991 Emerich DF, Zubricki EM, Shipley MT, Norman AB, Sanberg PR. Female rats are more sensitive to the locomotor alterations following quinolinic acid-induced striatal lesions: effects of striatal transplants. Experimental Neurology. 111: 369-78. PMID 1847880 DOI: 10.1016/0014-4886(91)90105-L  0.348
1990 Emerich DF, Walsh TJ. Cholinergic cell loss and cognitive impairments following intraventricular or intradentate injection of colchicine. Brain Research. 517: 157-67. PMID 2375986 DOI: 10.1016/0006-8993(90)91021-8  0.488
1990 Sanberg PR, Emerich DF. Neural basis of behavior: animal models of human conditions. Brain Research Bulletin. 25: 447-51. PMID 2292044 DOI: 10.1016/0361-9230(90)90237-T  0.32
1990 Emerich DF, Walsh TJ. Ganglioside AGF2 promotes task-specific recovery and attenuates the cholinergic hypofunction induced by AF64A. Brain Research. 527: 299-307. PMID 2253037 DOI: 10.1016/0006-8993(90)91150-F  0.465
1990 Emerich DF, Walsh TJ. Hyperactivity following intradentate injection of colchicine: a role for dopamine systems in the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 37: 149-54. PMID 2124711 DOI: 10.1016/0091-3057(90)90055-M  0.478
1990 Walsh TJ, Emerich DF. Cholinotoxic effects of intraventricular colchicine: A new model of cholinergic hypofunction European Journal of Pharmacology. 183: 1928. DOI: 10.1016/0014-2999(90)92274-M  0.321
1989 Walsh TJ, Emerich DF, Schmechel DE. GM1 ganglioside attenuates the behavioral deficits but not the granule cell damage produced by intradentate colchicine. Brain Research. 478: 24-33. PMID 2924118 DOI: 10.1016/0006-8993(89)91473-X  0.503
1989 Walsh TJ, Emerich DF, Bondy SC. Destruction of specific hippocampal cell fields increases ornithine decarboxylase activity: modulation of the biochemical but not the histological changes by ganglioside GM1. Experimental Neurology. 105: 54-61. PMID 2744127 DOI: 10.1016/0014-4886(89)90171-4  0.467
1989 Emerich DF, Walsh TJ. Selective working memory impairments following intradentate injection of colchicine: attenuation of the behavioral but not the neuropathological effects by gangliosides GM1 and AGF2. Physiology & Behavior. 45: 93-101. PMID 2727146 DOI: 10.1016/0031-9384(89)90170-4  0.471
1989 Flaherty CF, Rowan GA, Emerich DF, Walsh TJ. Effects of intrahippocampal administration of colchicine on incentive contrast and on radial maze performance. Behavioral Neuroscience. 103: 319-28. PMID 2706077 DOI: 10.1037/0735-7044.103.2.319  0.456
1988 Walsh TJ, Emerich DF. The hippocampus as a common target of neurotoxic agents. Toxicology. 49: 137-40. PMID 3287689 DOI: 10.1016/0300-483X(88)90185-0  0.438
1986 Tilson HA, Emerich D, Bondy SC. Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen Brain Research. 379: 147-150. PMID 2427159 DOI: 10.1016/0006-8993(86)90267-2  0.314
Low-probability matches (unlikely to be authored by this person)
2011 Ali OA, Doherty E, Bell WJ, Fradet T, Hudak J, Laliberte MT, Mooney DJ, Emerich DF. Biomaterial-based vaccine induces regression of established intracranial glioma in rats. Pharmaceutical Research. 28: 1074-80. PMID 21225320 DOI: 10.1007/S11095-010-0361-X  0.3
2007 Thanos CG, Schneider PA, Bintz BE, Jensen R, Bryant B, Bell WJ, Hudak J, Emerich DF. The in vitro expression and secretion of vascular endothelial growth factor from free and alginate-polyornithine encapsulated choroid plexus epithelium. Tissue Engineering. 13: 747-56. PMID 17432950 DOI: 10.1089/ten.2006.0294  0.299
2000 Bartus RT, Snodgrass P, Dean RL, Kordower JH, Emerich DF. Evidence that Cereport's ability to increase permeability of rat gliomas is dependent upon extent of tumor growth: implications for treating newly emerging tumor colonies. Experimental Neurology. 161: 234-44. PMID 10683290 DOI: 10.1006/Exnr.1999.7247  0.295
2016 Mahady L, Perez SE, Emerich DF, Wahlberg LU, Mufson EJ. Cholinergic Profiles in the Goettingen miniature pig (Sus scrofa domesticus) brain. The Journal of Comparative Neurology. PMID 27490949 DOI: 10.1002/cne.24087  0.294
2003 Bartus RT, Emerich DF, Hotz J, Blaustein M, Dean RL, Perdomo B, Basile AS. Vivitrex, an injectable, extended-release formulation of naltrexone, provides pharmacokinetic and pharmacodynamic evidence of efficacy for 1 month in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1973-82. PMID 12931140 DOI: 10.1038/Sj.Npp.1300274  0.294
1999 Bartus RT, Snodgrass P, Dean RL, Kim BS, Black K, Emerich DF. Use of Cereport(TM) (RMP-7) to increase delivery of carboplatin to gliomas: Insight and parameters for intracarotid infusion via a single-lumen cannula Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 6: 15-21. DOI: 10.1080/107175499267110  0.294
2000 Kordower JH, Isacson O, Leventhal L, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Progress in Brain Research. 127: 414-30. PMID 11142039 DOI: 10.1016/S0079-6123(00)27020-9  0.293
2000 Chen EY, Emerich DF, Bartus RT, Kordower JH. B2 bradykinin receptor immunoreactivity in rat brain. The Journal of Comparative Neurology. 427: 1-18. PMID 11042588 DOI: 10.1002/1096-9861(20001106)427:1<1::Aid-Cne1>3.0.Co;2-0  0.292
2002 Emerich DF. Article Commentary: Cell Transplantation for Parkinson's Disease. Cell Transplantation. 11: 1-3. PMID 28866913 DOI: 10.3727/096020198389726  0.289
1993 Sanberg PR, Emerich DF, el-Etri MM, Shipley MT, Zanol MD, Cahill DW, Norman AB. Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms. Pharmacology, Biochemistry, and Behavior. 46: 303-7. PMID 8265684 DOI: 10.1016/0091-3057(93)90357-Y  0.289
2010 Emerich DF, Orive G. Innovations In The Use Of Biomaterials For Treating Brain Disease Technology and Innovation. 12: 29-53. DOI: 10.3727/194982410X12741230805182  0.287
2009 Emerich DF, Vasconcellos A. Cellular transplants, 20 years later: the pharma initiative. Regenerative Medicine. 4: 485-7. PMID 19580397 DOI: 10.2217/rme.09.24  0.287
2004 Bartus RT, Emerich D, Snodgrass-Belt P, Fu K, Salzberg-Brenhouse H, Lafreniere D, Novak L, Lo ES, Cooper T, Basile AS. A pulmonary formulation of L-dopa enhances its effectiveness in a rat model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 310: 828-35. PMID 15039453 DOI: 10.1124/Jpet.103.064121  0.284
2009 Vasconcellos A, Ali OA, Emerich DF. Elevator Pitch: InCytu, Inc. Regenerative Medicine. 4: 357-8. PMID 19438308 DOI: 10.2217/rme.09.10  0.284
2002 Emerich DF, Snodgrass P, Lafreniere D, Dean RL, Salzberg H, Marsh J, Perdomo B, Arastu M, Winn SR, Bartus RT. Sustained release chemotherapeutic microspheres provide superior efficacy over systemic therapy and local bolus infusions. Pharmaceutical Research. 19: 1052-60. PMID 12180539 DOI: 10.1023/A:1016434926649  0.283
1990 Zubrycki EM, Emerich DF, Sanberg PR. Sex differences in regulatory changes following quinolinic acid-induced striatal lesions. Brain Research Bulletin. 25: 633-7. PMID 2148708 DOI: 10.1016/0361-9230(90)90125-J  0.283
2006 Thanos CG, Bintz BE, Bell WJ, Qian H, Schneider PA, MacArthur DH, Emerich DF. Intraperitoneal stability of alginate-polyornithine microcapsules in rats: an FTIR and SEM analysis. Biomaterials. 27: 3570-9. PMID 16497374 DOI: 10.1016/J.Biomaterials.2006.01.042  0.28
1998 Emerich DF, Granholm L. RECENT ADVANCES IN NEURAL TRANSPLANT RESEARCH. Cell Transplantation. 7: 83-85. PMID 28234070 DOI: 10.1177/096368979800700203  0.278
1997 Kordower JH, Mufson EJ, Fox N, Martel L, Emerich DF. Cellular delivery of NGF does not alter the expression of beta-amyloid immunoreactivity in young or aged nonhuman primates. Experimental Neurology. 145: 586-91. PMID 9217095 DOI: 10.1006/Exnr.1997.6492  0.276
1997 Cain CK, Francis JM, Plone MA, Emerich DF, Lindner MD. Pain-related disability and effects of chronic morphine in the adjuvant-induced arthritis model of chronic pain. Physiology & Behavior. 62: 199-205. PMID 9226363 DOI: 10.1016/S0031-9384(97)00158-3  0.274
2019 Nanobashvili A, Melin E, Emerich D, Tornøe J, Simonato M, Wahlberg L, Kokaia M. Unilateral ex vivo gene therapy by GDNF in epileptic rats. Gene Therapy. 26: 65-74. PMID 30464254 DOI: 10.1038/S41434-018-0050-7  0.271
1997 Lindner MD, Plone MA, Schallert T, Emerich DF. Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task. Brain Research. Cognitive Brain Research. 5: 329-33. PMID 9197520 DOI: 10.1016/S0926-6410(97)00006-2  0.27
1991 Joyce JN, Emerich DF, Norman AB, Sanberg PR. 30 – Regulation and Assessment of Receptors following Transplants Methods in Neurosciences. 7: 456-477. DOI: 10.1016/B978-0-12-185263-4.50035-2  0.27
2004 Emerich DF. Toward cell replacement therapy. Experimental Neurology. 187: 537; author reply 53. PMID 15144881 DOI: 10.1016/j.expneurol.2004.02.019  0.27
2000 Emerich DF. Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing? Trends in Neurosciences. 23: 245-6. PMID 10838591 DOI: 10.1016/S0166-2236(00)01573-3  0.268
2003 Emerich DF, Thanos CG. Nanotechnology and medicine. Expert Opinion On Biological Therapy. 3: 655-63. PMID 12831370 DOI: 10.1517/14712598.3.4.655  0.265
1994 Koutouzis TK, Emerich DF, Borlongan CV, Freeman TB, Cahill DW, Sanberg PR. Cell transplantation for central nervous system disorders. Critical Reviews in Neurobiology. 8: 125-62. PMID 7923393  0.264
2020 Izeia L, Eufrasio-da-Silva T, Dolatshahi-Pirouz A, Ostrovidov S, Paolone G, Peppas NA, De Vos P, Emerich D, Orive G. Cell-laden alginate hydrogels for the treatment of diabetes. Expert Opinion On Drug Delivery. PMID 32515621 DOI: 10.1080/17425247.2020.1778667  0.264
1999 Granholm AC, Emerich D. Fifth Annual Meeting of the American Society for Neural Transplantation and Repair. Cell Transplantation. 8: 7-9. PMID 28153075 DOI: 10.1177/096368979900800110  0.261
1996 Emerich DF, Plone M, Francis J, Frydel BR, Winn SR, Lindner MD. Alleviation of behavioral deficits in aged rodents following implantation of encapsulated GDNF-producing fibroblasts. Brain Research. 736: 99-110. PMID 8930314 DOI: 10.1016/S0006-8993(96)00683-X  0.261
1991 Emerich DF, Zanol MD, Norman AB, McConville BJ, Sanberg PR. Nicotine potentiates haloperidol-induced catalepsy and locomotor hypoactivity. Pharmacology, Biochemistry, and Behavior. 38: 875-80. PMID 1871200 DOI: 10.1016/0091-3057(91)90256-2  0.26
2006 Emerich DF, Thanos CG. The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis. Biomolecular Engineering. 23: 171-84. PMID 16843058 DOI: 10.1016/J.Bioeng.2006.05.026  0.256
2007 Emerich DF, Thanos CG. Targeted nanoparticle-based drug delivery and diagnosis. Journal of Drug Targeting. 15: 163-83. PMID 17454354 DOI: 10.1080/10611860701231810  0.254
1996 Plone MA, Emerich DF, Lindner MD. Individual differences in the hotplate test and effects of habituation on sensitivity to morphine. Pain. 66: 265-70. PMID 8880849 DOI: 10.1016/0304-3959(96)03048-5  0.254
2009 Ali OA, Emerich D, Dranoff G, Mooney DJ. In situ regulation of DC subsets and T cells mediates tumor regression in mice. Science Translational Medicine. 1: 8ra19. PMID 20368186 DOI: 10.1126/Scitranslmed.3000359  0.249
2005 Emerich DF. Nanomedicine--prospective therapeutic and diagnostic applications. Expert Opinion On Biological Therapy. 5: 1-5. PMID 15709905 DOI: 10.1517/14712598.5.1.1  0.248
2009 Orive G, Anitua E, Pedraz JL, Emerich DF. Biomaterials for promoting brain protection, repair and regeneration. Nature Reviews. Neuroscience. 10: 682-92. PMID 19654582 DOI: 10.1038/nrn2685  0.248
1999 Bartus RT, Emerich DF. Cholinergic markers in Alzheimer disease. Jama. 282: 2208-9. PMID 10605966 DOI: 10.1001/Jama.282.23.2208  0.245
2013 Borlongan CV, Burns J, Tajiri N, Stahl CE, Weinbren NL, Shojo H, Sanberg PR, Emerich DF, Kaneko Y, van Loveren HR. Epidemiological survey-based formulae to approximate incidence and prevalence of neurological disorders in the United States: a meta-analysis. Plos One. 8: e78490. PMID 24205243 DOI: 10.1371/Journal.Pone.0078490  0.245
1998 Bartus RT, Tracy MA, Emerich DF, Zale SE. Sustained delivery of proteins for novel therapeutic agents. Science (New York, N.Y.). 281: 1161-2. PMID 9735031 DOI: 10.1126/Science.281.5380.1161  0.244
1993 Johnson TW, Polger S, Emerich DF, Freeman TB, Cahill DW, Sanberg PR. Neuroleptic dysphoria: in search of an animal model. The International Journal of Neuroscience. 70: 271-5. PMID 8063545 DOI: 10.3109/00207459309000581  0.244
2009 Emerich DF. Discontinued biological drugs in 2008. Expert Opinion On Biological Therapy. 9: 1453-61. PMID 19916730 DOI: 10.1517/14712590903307396  0.229
1994 Mufson EJ, Benzing WC, Cole GM, Wang H, Emerich DF, Sladek JR, Morrison JH, Kordower JH. Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques. Neurobiology of Aging. 15: 621-7. PMID 7824054 DOI: 10.1016/0197-4580(94)00064-6  0.225
2002 Emerich DF. Cell transplantation for Parkinson's disease. Cell Transplantation. 11: 1-3. PMID 12095215  0.223
1992 Sanberg PR, Koutouzis TK, Freeman TB, Emerich DF, Bertino AM, Cahill DW. Cell transplantation for Huntington's disease. Transplantation Proceedings. 24: 3015-6. PMID 1361271  0.222
2002 Emerich DF, Winn SR, Bartus RT. Injection of Chemotherapeutic Microspheres and Glioma IV: Eradicating Tumors in Rats. Cell Transplantation. 11: 47-54. PMID 28866915 DOI: 10.3727/096020198389771  0.222
2003 Dufour JM, Rajotte RV, Korbutt GS, Emerich DF. Harnessing the immunomodulatory properties of Sertoli cells to enable xenotransplantation in type I diabetes. Immunological Investigations. 32: 275-97. PMID 14603995  0.215
1995 Kordower JH, Liu Y, Winn S, Emerich DF. Encapsulated PC 12 Cell Transplants into Hemiparkinsonian Monkeys: A Behavioral, Neuroanatomical, and Neurochemical Analysis Cell Transplantation. 4: 155-171. DOI: 10.1177/096368979500400203  0.214
2007 Thanos CG, Emerich DF. Choroid Plexus Epithelial Cell Transplants for Repair of the Brain Cellular Transplantation. 399-416. DOI: 10.1016/B978-012369415-7/50024-7  0.214
1995 Hammang JP, Emerich DF, Winn SR, Lee A, Lindner MD, Gentile FT, Doherty EJ, Kordower JH, Baetge EE. DELIVERY OF NEUROTROPHIC FACTORS TO THE CNS USING ENCAPSULATED CELLS: DEVELOPING TREATMENTS FOR NEURODEGENERATIVE DISEASES. Cell Transplantation. 4: 27-28. PMID 28173905  0.212
2014 Orive G, Emerich D, De Vos P. Encapsulate this: The do's and don'ts Nature Medicine. 20: 233. PMID 24603789 DOI: 10.1038/nm.3486  0.211
1992 Sanberg PR, Emerich DF, McConville BJ, Cahill DW, Norman AB. NICOTINE IMPROVES NEUROLEPTIC RESPONSE IN TOURETTE SYNDROME: PRECLINICAL AND CLINICAL EVIDENCE Clinical Neuropharmacology. 15: 271B. DOI: 10.1097/00002826-199202001-00524  0.211
2005 Winn SR, Emerich DF. Managing chronic pain with encapsulated cell implants releasing catecholamines and endogenous opiods. Frontiers in Bioscience : a Journal and Virtual Library. 10: 367-78. PMID 15574375  0.209
2007 Thanos CG, Bintz BE, Emerich DF. Stability of alginate-polyornithine microcapsules is profoundly dependent on the site of transplantation. Journal of Biomedical Materials Research. Part A. 81: 1-11. PMID 17089418 DOI: 10.1002/Jbm.A.31033  0.207
2021 Amalric M, Pattij T, Sotiropoulos I, Silva JM, Sousa N, Ztaou S, Chiamulera C, Wahlberg LU, Emerich DF, Paolone G. Where Dopaminergic and Cholinergic Systems Interact: A Gateway for Tuning Neurodegenerative Disorders. Frontiers in Behavioral Neuroscience. 15: 661973. PMID 34366802 DOI: 10.3389/fnbeh.2021.661973  0.207
2007 Emerich DF, Halberstadt C. Nanotechnology's Impact on Cell Transplantation Cellular Transplantation. 611-627. DOI: 10.1016/B978-012369415-7/50033-8  0.204
2006 Halberstadt C, Emerich DF, Gonsalves K. Nano to the meso scale: influence on cell transplantation. Discovery Medicine. 6: 234-8. PMID 17250789  0.204
2004 Emerich DF. BRIEF COMMUNICATION Dose-Dependent Neurochemical and Functional Protection Afforded by Encapsulated CNTF-Producing Cells. Cell Transplantation. 13: 839-844. PMID 28281990 DOI: 10.3727/000000004783983404  0.204
2007 Dalgleish A, Emerich D, Glassy M, Kreitman RJ, Mironov V, Morse M, Santini D. Editorial Board Focus – February 2007 Expert Opinion On Biological Therapy. 7: 157-160. DOI: 10.1517/14712598.7.2.157  0.198
2004 Emerich DF. Article Commentary: The Convergence of Cell Transplantation and Nanoengineering. Cell Transplantation. 13: 477-480. PMID 28858581 DOI: 10.3727/000000004783983657  0.193
2002 Emerich DF, Sanberg PR. Article Commentary: Novel Means to Selectively Identify Sertoli Cell Transplants. Cell Transplantation. 11: 495-497. PMID 28866937 DOI: 10.3727/000000002783985594  0.19
2005 Garkavenko O, Emerich DF, Muzina M, Muzina Z, Vasconcellos AV, Ferguson AB, Cooper IJ, Elliott RB. Xenotransplantation of neonatal porcine liver cells. Transplantation Proceedings. 37: 477-80. PMID 15808681 DOI: 10.1016/j.transproceed.2004.12.183  0.189
1996 Emerich DF, Lindner MD, Winn SR, Chen E, Frydel BR, Kordower JH. Implants of Encapsulated Human CNTF-Producing Fibroblasts Prevent Behavioral Deficits and Striatal Degeneration in a Rodent Model of Huntington’s Disease The Journal of Neuroscience. 16: 5168-5181. DOI: 10.1523/JNEUROSCI.16-16-05168.1996  0.188
2021 Paez-Mayorga J, Lukin I, Emerich D, de Vos P, Orive G, Grattoni A. Emerging strategies for beta cell transplantation to treat diabetes. Trends in Pharmacological Sciences. 43: 221-233. PMID 34887129 DOI: 10.1016/j.tips.2021.11.007  0.188
1996 Kordower JH, Chen EY, Mufson EJ, Winn SR, Emerich DF. Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons. Neuroscience. 72: 63-77. PMID 8730706 DOI: 10.1016/0306-4522(95)00543-9  0.187
2002 Emerich DF, Winn SR, Bartus RT. Injection of Chemotherapeutic Microspheres and Glioma III: Parameters to Optimize Efficacy. Cell Transplantation. 11: 35-45. PMID 28866916 DOI: 10.3727/096020198389762  0.186
1985 Emerich DF, Scalzo FM, Enters EK, Spear NE, Spear LP. Effects of 6-hydroxydopamine-induced catecholamine depletion on shock-precipitated wall climbing of infant rat pups. Developmental Psychobiology. 18: 215-27. PMID 3921418 DOI: 10.1002/dev.420180303  0.185
2020 Wahlberg LU, Emerich DF, Kordower JH, Bell W, Fradet T, Paolone G. Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain Current Research in Pharmacology and Drug Discovery. 1: 19-29. DOI: 10.1016/j.crphar.2020.04.001  0.183
2007 Thanos C, Emerich DF. Neurotrophic Cell Transplants for Degenerative Diseases of the Eye Cellular Transplantation. 327-343. DOI: 10.1016/B978-012369415-7/50019-3  0.183
2011 Chilkoti A, Mohapatra S, Cameron DF, Haynie D, Larson D, Lal R, Busnaina A, Clark H, Leong KW, Borenstein J, Webster TJ, Gallant N, Seal S, Sladek J, Mohapatra SS, ... ... Emerich DF, et al. ABSTRACTS FROM THE 2010 NANOBIO COLLABORATIVE (NBC) CONFERENCE Technology & Innovation. 13: 83-92. DOI: 10.3727/194982411X13003853540153  0.18
2004 Emerich DF. The emerging technologies of neural xenografting and stem cell transplantation for treating neurodegenerative disorders. Drugs of Today (Barcelona, Spain : 1998). 40: 271. PMID 15148535  0.178
1997 Lindner MD, Plone MA, Frydel B, Kaplan FA, Krueger PM, Bell WJ, Blaney TJ, Winn SR, Sherman SS, Doherty EJ, Emerich DF. Intraventricular encapsulated calf adrenal chromaffin cells: Viable for at least 500 days in vivo without detectable adverse effects on behavioral/cognitive function or host immune sensitization in rats Restorative Neurology and Neuroscience. 11: 21-35.  0.178
2001 Emerich DF, Salzberg HC. Tribute to Dr. Thomas J. Walsh. Cell Transplantation. 10: 1-2. PMID 28880669 DOI: 10.3727/000000001783987052  0.176
2000 Bartus RT, Snodgrass P, Marsh J, Agostino M, Perkins A, Emerich DF. Intravenous cereport (RMP-7) modifies topographic uptake profile of carboplatin within rat glioma and brain surrounding tumor, elevates platinum levels, and enhances survival. The Journal of Pharmacology and Experimental Therapeutics. 293: 903-11. PMID 10869391  0.172
2010 Orive G, Ali OA, Anitua E, Pedraz JL, Emerich DF. Biomaterial-based technologies for brain anti-cancer therapeutics and imaging. Biochimica Et Biophysica Acta. 1806: 96-107. PMID 20406668 DOI: 10.1016/j.bbcan.2010.04.001  0.169
1993 Emerich DF, Frydel BR, Flanagan TR, Palmatier M, Winn SR, Christenson L. Transplantation of polymer encapsulated PC12 cells: Use of chitosan as an immobilization matrix Cell Transplantation. 2: 241-249.  0.166
2005 Elliott RB, Escobar L, Tan PL, Garkavenko O, Calafiore R, Basta P, Vasconcellos AV, Emerich DF, Thanos C, Bambra C. Intraperitoneal alginate-encapsulated neonatal porcine islets in a placebo-controlled study with 16 diabetic cynomolgus primates. Transplantation Proceedings. 37: 3505-8. PMID 16298643 DOI: 10.1016/j.transproceed.2005.09.038  0.166
2003 Bartus RT, Emerich DF, Hotz J, Blaustein M, Dean RL, Perdomo B, Basile AS. Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for I Month in Rats Neuropsychopharmacology. 28: 1973-1982.  0.165
2010 Emerich DF, Orive G. Nanoparticle-Based Technologies for Treating and Imaging Brain Tumors. Current Cancer Drug Targets. PMID 21158722  0.159
2007 Thanos CG, Calafiore R, Basta G, Bintz BE, Bell WJ, Hudak J, Vasconcellos A, Schneider P, Skinner SJ, Geaney M, Tan P, Elliot RB, Tatnell M, Escobar L, Qian H, ... ... Emerich DF, et al. Formulating the alginate-polyornithine biocapsule for prolonged stability: evaluation of composition and manufacturing technique. Journal of Biomedical Materials Research. Part A. 83: 216-24. PMID 17607741 DOI: 10.1002/Jbm.A.31472  0.157
1997 Subramanian T, Emerich DF, Bakay RAE, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Polymer-Encapsulated PC-12 Cells Demonstrate High-Affinity Uptake of Dopamine in Vitro and18F-DOPA Uptake and Metabolism after Intracerebral Implantation in Nonhuman Primates Cell Transplantation. 6: 469-477. DOI: 10.1177/096368979700600506  0.153
2007 Halberstadt C, Emerich D. Cellular Transplantation Cellular Transplantation 0.153
2005 Emerich DF, Skinner SJM, Borlongan CV, Thanos CG. A Role of the Choroid Plexus in Transplantation Therapy. Cell Transplantation. 14: 715-725. PMID 28849978 DOI: 10.3727/000000005783982576  0.152
2008 Emerich DF, Thanos CG. NT-501: an ophthalmic implant of polymer-encapsulated ciliary neurotrophic factor-producing cells. Current Opinion in Molecular Therapeutics. 10: 506-15. PMID 18830926  0.151
2011 Ali OA, Doherty E, Mooney DJ, Emerich D. Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines. Biomatter. 1: 66-75. PMID 23507728 DOI: 10.4161/biom.1.1.16277  0.151
1998 Emerich DF, Granholm L. Recent advances in neural transplant research Cell Transplantation. 7: 83-85. DOI: 10.1016/S0963-6897(98)00014-1  0.14
2007 Emerich DF, Halberstadt C, Thanos C. Role of nanobiotechnology in cell-based nanomedicine: A concise review Journal of Biomedical Nanotechnology. 3: 235-244. DOI: 10.1166/Jbn.2007.036  0.128
2001 Emerich DF, Dean RL, Snodgrass P, Lafreniere D, Agostino M, Wiens T, Xiong H, Hasler B, Marsh J, Pink M, Kim BS, Perdomo B, Bartus RT. Bradykinin modulation of tumor vasculature: II. activation of nitric oxide and phospholipase A2/prostaglandin signaling pathways synergistically modifies vascular physiology and morphology to enhance delivery of chemotherapeutic agents to tumors. The Journal of Pharmacology and Experimental Therapeutics. 296: 632-41. PMID 11160652  0.127
2001 Emerich DF, Snodgrass P, Dean RL, Lafreniere D, Agostino M, Wiens T, Xiong H, Hasler B, Marsh J, Pink M, Kim BS, Bartus RT. Bradykinin modulation of tumor vasculature: I. Activation of B2 receptors increases delivery of chemotherapeutic agents into solid peripheral tumors, enhancing their efficacy. The Journal of Pharmacology and Experimental Therapeutics. 296: 623-31. PMID 11160651  0.125
1991 Emerich DF, Norman AB, Sanberg PR. Nicotine potentiates the behavioral effects of haloperidol. Psychopharmacology Bulletin. 27: 385-90. PMID 1775613  0.121
2000 Emerich DF. Recent efforts to overcome the blood-brain barrier for drug delivery Expert Opinion On Therapeutic Patents. 10: 279-287.  0.12
2008 Emerich DF, Thanos CG. Multifunctional peptide-based nanosystems for improving delivery and molecular imaging. Current Opinion in Molecular Therapeutics. 10: 132-9. PMID 18386225  0.118
2020 Policastro G, Brunelli M, Tinazzi M, Chiamulera C, Emerich DF, Paolone G. Cytokine-, Neurotrophin-, and Motor Rehabilitation-Induced Plasticity in Parkinson's Disease. Neural Plasticity. 2020: 8814028. PMID 33293946 DOI: 10.1155/2020/8814028  0.11
2010 Borlongan CV, Emerich DF. Choroid Plexus and Immune Response of the Brain New Insights to Neuroimmune Biology. 75-91. DOI: 10.1016/B978-0-12-384691-4.00004-3  0.091
1992 SANBERG PR, EMERICH DF. HUNTINGTONS CHOREA AND COGNITIVE DISORDERS Behavioural Pharmacology. 3: 27. DOI: 10.1097/00008877-199204001-00077  0.046
1991 Emerich DF, Sanberg PR. Neuroleptic dysphoria. Biological Psychiatry. 29: 201-3. PMID 1673062 DOI: 10.1016/0006-3223(91)91281-U  0.036
1994 Babensee J, Bäckman C, Baker BJ, Banks W, Barker R, Berry M, Biddle PT, Brem H, Bridges RJ, Broadwell RD, Camarata PJ, Carmichael SW, Carvey PM, Chalmers GR, Boni UD, ... ... Emerich DF, et al. Contributors to Volume 21 Methods in Neurosciences. 21. DOI: 10.1016/B978-0-12-185291-7.50004-7  0.027
1991 Emerich DF, Sanberg PR. Response Biological Psychiatry. 30: 847-848. DOI: 10.1016/0006-3223(91)90243-F  0.011
2007 Halberstadt CR, Emerich DF. Preface Cellular Transplantation. xiii-xiv. DOI: 10.1016/B978-012369415-7/50001-6  0.01
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