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Joshua J. McElwee, Ph.D. - Publications

Affiliations: 
2004 University of Washington, Seattle, Seattle, WA 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Ma CA, Stinson JR, Zhang Y, Abbott JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa N, Arjunaraja S, Voss K, ... ... McElwee JJ, et al. Germline hypomorphic CARD11 mutations in severe atopic disease. Nature Genetics. PMID 28628108 DOI: 10.1038/Ng.3898  0.362
2017 Afzali B, Grönholm J, Vandrovcova J, O'Brien C, Sun HW, Vanderleyden I, Davis FP, Khoder A, Zhang Y, Hegazy AN, Villarino AV, Palmer IW, Kaufman J, Watts NR, Kazemian M, ... ... McElwee J, et al. BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency. Nature Immunology. PMID 28530713 DOI: 10.1038/Ni.3753  0.324
2015 Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y, Liu Z, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, ... ... McElwee J, et al. AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy. Science (New York, N.Y.). 349: 436-40. PMID 26206937 DOI: 10.1126/Science.Aaa1663  0.345
2015 Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson ED, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, ... ... McElwee J, et al. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood. 125: 591-9. PMID 25359994 DOI: 10.1182/Blood-2014-09-602763  0.362
2014 Lucas CL, Zhang Y, Venida A, Wang Y, Hughes J, McElwee J, Butrick M, Matthews H, Price S, Biancalana M, Wang X, Richards M, Pozos T, Barlan I, Ozen A, et al. Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K. The Journal of Experimental Medicine. 211: 2537-47. PMID 25488983 DOI: 10.1084/Jem.20141759  0.365
2014 Kuehn HS, Ouyang W, Lo B, Deenick EK, Niemela JE, Avery DT, Schickel JN, Tran DQ, Stoddard J, Zhang Y, Frucht DM, Dumitriu B, Scheinberg P, Folio LR, Frein CA, ... ... McElwee J, et al. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. Science (New York, N.Y.). 345: 1623-7. PMID 25213377 DOI: 10.1126/Science.1255904  0.309
2014 Liu Y, Jesus AA, Marrero B, Yang D, Ramsey SE, Montealegre Sanchez GA, Tenbrock K, Wittkowski H, Jones OY, Kuehn HS, Lee CC, DiMattia MA, Cowen EW, Gonzalez B, Palmer I, ... ... McElwee J, et al. Activated STING in a vascular and pulmonary syndrome. The New England Journal of Medicine. 371: 507-18. PMID 25029335 DOI: 10.1056/Nejmoa1312625  0.393
2014 Zhang Y, Yu X, Ichikawa M, Lyons JJ, Datta S, Lamborn IT, Jing H, Kim ES, Biancalana M, Wolfe LA, DiMaggio T, Matthews HF, Kranick SM, Stone KD, Holland SM, ... ... McElwee J, et al. Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment. The Journal of Allergy and Clinical Immunology. 133: 1400-9, 1409.e1-5. PMID 24589341 DOI: 10.1016/J.Jaci.2014.02.013  0.35
2011 Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 477: 482-5. PMID 21938067 DOI: 10.1038/Nature10296  0.366
2010 Schuster E, McElwee JJ, Tullet JM, Doonan R, Matthijssens F, Reece-Hoyes JS, Hope IA, Vanfleteren JR, Thornton JM, Gems D. DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO. Molecular Systems Biology. 6: 399. PMID 20706209 DOI: 10.1038/Msb.2010.54  0.467
2008 Doonan R, McElwee JJ, Matthijssens F, Walker GA, Houthoofd K, Back P, Matscheski A, Vanfleteren JR, Gems D. Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans. Genes & Development. 22: 3236-41. PMID 19056880 DOI: 10.1101/Gad.504808  0.365
2008 Patel DS, Garza-Garcia A, Nanji M, McElwee JJ, Ackerman D, Driscoll PC, Gems D. Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor. Genetics. 178: 931-46. PMID 18245374 DOI: 10.1534/Genetics.107.070813  0.398
2008 Piper MD, Selman C, McElwee JJ, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? Journal of Internal Medicine. 263: 179-91. PMID 18226095 DOI: 10.1111/J.1365-2796.2007.01906.X  0.42
2007 McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biology. 8: R132. PMID 17612391 DOI: 10.1186/Gb-2007-8-7-R132  0.547
2006 McElwee JJ, Schuster E, Blanc E, Thornton J, Gems D. Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472]. Mechanisms of Ageing and Development. 127: 922-36. PMID 17216712 DOI: 10.1016/J.Mad.2006.10.002  0.424
2006 McElwee JJ, Schuster E, Blanc E, Thornton J, Gems D. Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans. Mechanisms of Ageing and Development. 127: 458-72. PMID 16522328 DOI: 10.1016/J.Mad.2006.01.006  0.418
2005 Gems D, McElwee JJ. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling? Mechanisms of Ageing and Development. 126: 381-7. PMID 15664624 DOI: 10.1016/J.Mad.2004.09.001  0.425
2005 Piper MDW, Selman C, McElwee JJ, Partridge L. Models of insulin signalling and longevity Drug Discovery Today: Disease Models. 2: 249-256. DOI: 10.1016/J.Ddmod.2005.11.001  0.417
2004 McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D. Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. The Journal of Biological Chemistry. 279: 44533-43. PMID 15308663 DOI: 10.1074/Jbc.M406207200  0.55
2003 McElwee J, Bubb K, Thomas JH. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell. 2: 111-21. PMID 12882324 DOI: 10.1046/J.1474-9728.2003.00043.X  0.55
2003 Gems D, McElwee JJ. Ageing: Microarraying mortality. Nature. 424: 259-61. PMID 12867961 DOI: 10.1038/424259A  0.342
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