Nilabh Shastri - Publications

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Mechanisms of immunesurveillance

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Manoharan Valerio M, Arana K, Guan J, Chan SW, Yang X, Kurd N, Lee A, Shastri N, Coscoy L, Robey EA. The promiscuous development of an unconventional Qa1b-restricted T cell population. Frontiers in Immunology. 14: 1250316. PMID 38022509 DOI: 10.3389/fimmu.2023.1250316  0.403
2023 El Bissati K, Krishack PA, Zhou Y, Weber CR, Lykins J, Jankovic D, Edelblum KL, Fraczek L, Grover H, Chentoufi AA, Singh G, Reardon C, Dubey JP, Reed S, Alexander J, ... ... Shastri N, et al. CD4 T Cell Responses to Are a Double-Edged Sword. Vaccines. 11. PMID 37766162 DOI: 10.3390/vaccines11091485  0.335
2023 Geiger KM, Manoharan M, Coombs R, Arana K, Park CS, Lee AY, Shastri N, Robey EA, Coscoy L. Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self. Cell Reports. 42: 112317. PMID 36995940 DOI: 10.1016/j.celrep.2023.112317  0.462
2023 Guan J, Valerio MM, Peske JD, Park C, Robey EA, Sadegh-Nasseri S, Shastri N. Commensal Bacteria Maintain a Qa-1 -restricted Unconventional CD8 T Population in Gut Epithelium. Biorxiv : the Preprint Server For Biology. PMID 36909616 DOI: 10.1101/2023.03.01.530600  0.71
2022 Martín-Esteban A, Rodriguez JC, Peske D, Lopez de Castro JA, Shastri N, Sadegh-Nasseri S. The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities. Frontiers in Immunology. 13: 1066483. PMID 36569828 DOI: 10.3389/fimmu.2022.1066483  0.809
2021 Guan J, Peske JD, Taylor JA, Shastri N. The nonclassical immune surveillance for ERAAP function. Current Opinion in Immunology. 70: 105-111. PMID 34098489 DOI: 10.1016/j.coi.2021.05.008  0.702
2019 Kanaseki T, Shastri N. Biochemical Analysis of Naturally Processed Antigenic Peptides Presented by MHC Class I Molecules. Methods in Molecular Biology (Clifton, N.J.). 1988: 101-108. PMID 31147935 DOI: 10.1007/978-1-4939-9450-2_8  0.703
2019 D'Souza MP, Adams E, Altman JD, Birnbaum ME, Boggiano C, Casorati G, Chien YH, Conley A, Eckle SBG, Früh K, Gondré-Lewis T, Hassan N, Huang H, Jayashankar L, Kasmar AG, ... ... Shastri N, et al. Casting a wider net: Immunosurveillance by nonclassical MHC molecules. Plos Pathogens. 15: e1007567. PMID 30789961 DOI: 10.1371/Journal.Ppat.1007567  0.571
2018 Guan J, Shastri N. A peptide puzzle. Elife. 7. PMID 30526851 DOI: 10.7554/eLife.41524  0.454
2018 Zhang J, Yang SJ, Gonzalez F, Yang J, Zhang Y, He M, Shastri N, Murthy N. A peptide-based fluorescent probe images ERAAP activity in cells and in high throughput assays. Chemical Communications (Cambridge, England). PMID 29897370 DOI: 10.1039/C7Cc09598H  0.431
2018 Shastri N, Endert PV. Decision letter: TAPBPR mediates peptide dissociation from MHC class I using a leucine lever Elife. DOI: 10.7554/Elife.40126.038  0.623
2017 Sa Q, Ochiai E, Tiwari A, Mullins J, Shastri N, Mercier C, Cesbron-Delauw MF, Suzuki Y. Determination of a Key Antigen for Immunological Intervention To Target the Latent Stage of Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). PMID 28446567 DOI: 10.4049/Jimmunol.1700062  0.41
2017 Guan J, Yang SJ, Gonzalez F, Yin Y, Shastri N. Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant αβ TCRs Specific for a Conserved Peptide-Qa-1b MHC Class Ib Ligand. Journal of Immunology (Baltimore, Md. : 1950). PMID 28108559 DOI: 10.4049/Jimmunol.1600764  0.645
2016 Prasad S, Starck SR, Shastri N. Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli. Journal of Immunology (Baltimore, Md. : 1950). PMID 27647836 DOI: 10.4049/Jimmunol.1502045  0.684
2016 Chu HH, Chan SW, Gosling JP, Blanchard N, Tsitsiklis A, Lythe G, Shastri N, Molina-París C, Robey EA. Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population. Immunity. 45: 159-171. PMID 27421704 DOI: 10.1016/J.Immuni.2016.06.013  0.403
2016 Sanecka A, Yoshida N, Dougan SK, Jackson J, Shastri N, Ploegh H, Blanchard N, Frickel EM. Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute phase Toxoplasma gondii burden. Immunology. PMID 27377596 DOI: 10.1111/Imm.12643  0.474
2016 Nagarajan NA, de Verteuil DA, Sriranganadane D, Yahyaoui W, Thibault P, Perreault C, Shastri N. ERAAP Shapes the Peptidome Associated with Classical and Nonclassical MHC Class I Molecules. Journal of Immunology (Baltimore, Md. : 1950). PMID 27371725 DOI: 10.4049/Jimmunol.1500654  0.728
2016 Starck SR, Shastri N. Nowhere to hide: unconventional translation yields cryptic peptides for immune surveillance. Immunological Reviews. 272: 8-16. PMID 27319338 DOI: 10.1111/Imr.12434  0.735
2016 Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P. Translation from the 5' untranslated region shapes the integrated stress response. Science (New York, N.Y.). 351: aad3867. PMID 26823435 DOI: 10.1126/Science.Aad3867  0.703
2015 Shastri N, Yewdell JW. Editorial overview: Antigen processing and presentation: Where cellular immunity begins. Current Opinion in Immunology. 34: v-vii. PMID 25964203 DOI: 10.1016/J.Coi.2015.04.004  0.358
2014 Grover HS, Chu HH, Kelly FD, Yang SJ, Reese ML, Blanchard N, Gonzalez F, Chan SW, Boothroyd JC, Shastri N, Robey EA. Impact of regulated secretion on antiparasitic CD8 T cell responses. Cell Reports. 7: 1716-28. PMID 24857659 DOI: 10.1016/J.Celrep.2014.04.031  0.414
2014 Shastri N, Nagarajan N, Lind KC, Kanaseki T. Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum. Current Opinion in Immunology. 26: 123-7. PMID 24556408 DOI: 10.1016/J.Coi.2013.11.006  0.844
2014 Chen L, Fischer R, Peng Y, Reeves E, McHugh K, Ternette N, Hanke T, Dong T, Elliott T, Shastri N, Kollnberger S, James E, Kessler B, Bowness P. Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27. Arthritis & Rheumatology (Hoboken, N.J.). 66: 284-94. PMID 24504800 DOI: 10.1002/Art.38249  0.615
2013 Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri N. ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides. Journal of Immunology (Baltimore, Md. : 1950). 191: 1547-55. PMID 23863903 DOI: 10.4049/Jimmunol.1301043  0.852
2013 Feliu V, Vasseur V, Grover HS, Chu HH, Brown MJ, Wang J, Boyle JP, Robey EA, Shastri N, Blanchard N. Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite. Plos Pathogens. 9: e1003449. PMID 23818852 DOI: 10.1371/Journal.Ppat.1003449  0.582
2013 Nagarajan NA, Shastri N. Immune surveillance for ERAAP dysfunction. Molecular Immunology. 55: 120-2. PMID 23433779 DOI: 10.1016/J.Molimm.2012.10.006  0.678
2013 Kanaseki T, Shastri N. Biochemical analysis of naturally processed antigenic peptides presented by MHC class I molecules. Methods in Molecular Biology (Clifton, N.J.). 960: 179-85. PMID 23329488 DOI: 10.1007/978-1-62703-218-6_15  0.698
2012 Grover HS, Blanchard N, Gonzalez F, Chan S, Robey EA, Shastri N. The Toxoplasma gondii peptide AS15 elicits CD4 T cells that can control parasite burden. Infection and Immunity. 80: 3279-88. PMID 22778097 DOI: 10.1128/Iai.00425-12  0.54
2012 Starck SR, Jiang V, Pavon-Eternod M, Prasad S, McCarthy B, Pan T, Shastri N. Leucine-tRNA initiates at CUG start codons for protein synthesis and presentation by MHC class I. Science (New York, N.Y.). 336: 1719-23. PMID 22745432 DOI: 10.1126/Science.1220270  0.547
2012 Nagarajan NA, Gonzalez F, Shastri N. Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum. Nature Immunology. 13: 579-86. PMID 22522492 DOI: 10.1038/Ni.2282  0.676
2012 Shastri N, Starck S, Jiang V, Pavon-Eternod M, Prasad S, McCarthy B, Pan T. A novel transfer RNA shapes the cryptic peptide repertoire presented by MHC class I molecules Molecular Immunology. 51: 30. DOI: 10.1016/J.Molimm.2012.02.082  0.588
2012 Nagarajan N, Gonzalez F, Shastri N. Cytotoxic T cells specific for the non-classical MHC class I molecule Qa-1 detect defects in ER antigen processing Molecular Immunology. 51: 26. DOI: 10.1016/J.Molimm.2012.02.070  0.514
2012 Grover H, Vasseur V, Féliu V, Wang J, Boyle J, Chu H, Chéneau C, Robey E, Shastri N, Blanchard N. Protein topology and epitope position play a critical role in shaping CD8 T cell immunodominance to the Toxoplasma gondii parasite Molecular Immunology. 51: 9. DOI: 10.1016/J.Molimm.2012.02.018  0.387
2011 Starck SR, Shastri N. Non-conventional sources of peptides presented by MHC class I. Cellular and Molecular Life Sciences : Cmls. 68: 1471-9. PMID 21390547 DOI: 10.1007/S00018-011-0655-0  0.663
2010 Blanchard N, Shastri N. Topological journey of parasite-derived antigens for presentation by MHC class I molecules. Trends in Immunology. 31: 414-21. PMID 20869317 DOI: 10.1016/J.It.2010.08.004  0.453
2010 Blanchard N, Kanaseki T, Escobar H, Delebecque F, Nagarajan NA, Reyes-Vargas E, Crockett DK, Raulet DH, Delgado JC, Shastri N. Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 3033-42. PMID 20173027 DOI: 10.4049/Jimmunol.0903712  0.734
2010 Blanchard N, Shastri N. Cross-presentation of peptides from intracellular pathogens by MHC class I molecules. Annals of the New York Academy of Sciences. 1183: 237-50. PMID 20146719 DOI: 10.1111/J.1749-6632.2009.05135.X  0.578
2010 Cardinaud S, Starck SR, Chandra P, Shastri N. The synthesis of truncated polypeptides for immune surveillance and viral evasion. Plos One. 5: e8692. PMID 20098683 DOI: 10.1371/Journal.Pone.0008692  0.613
2009 Homhuan A, Kogure K, Nakamura T, Shastri N, Harashima H. Enhanced antigen presentation and CTL activity by transduction of mature rather than immature dendritic cells with octaarginine-modified liposomes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 136: 79-85. PMID 19344678 DOI: 10.1016/J.Jconrel.2009.01.004  0.342
2008 Starck SR, Ow Y, Jiang V, Tokuyama M, Rivera M, Qi X, Roberts RW, Shastri N. A distinct translation initiation mechanism generates cryptic peptides for immune surveillance. Plos One. 3: e3460. PMID 18941630 DOI: 10.1371/Journal.Pone.0003460  0.844
2008 Kanaseki T, Shastri N. Endoplasmic reticulum aminopeptidase associated with antigen processing regulates quality of processed peptides presented by MHC class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 181: 6275-82. PMID 18941218 DOI: 10.4049/Jimmunol.181.9.6275  0.721
2008 Starck SR, Cardinaud S, Shastri N. Immune surveillance obstructed by viral mRNA. Proceedings of the National Academy of Sciences of the United States of America. 105: 9135-6. PMID 18599434 DOI: 10.1073/Pnas.0804456105  0.492
2008 Blanchard N, Gonzalez F, Schaeffer M, Joncker NT, Cheng T, Shastri AJ, Robey EA, Shastri N. Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nature Immunology. 9: 937-44. PMID 18587399 DOI: 10.1038/Ni.1629  0.447
2008 Nakamura T, Moriguchi R, Kogure K, Shastri N, Harashima H. Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1507-14. PMID 18560420 DOI: 10.1038/Mt.2008.122  0.453
2008 Fassò M, Waitz R, Hou Y, Rim T, Greenberg NM, Shastri N, Fong L, Allison JP. SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade. Proceedings of the National Academy of Sciences of the United States of America. 105: 3509-14. PMID 18303116 DOI: 10.1073/Pnas.0712269105  0.419
2008 Blanchard N, Shastri N. Coping with loss of perfection in the MHC class I peptide repertoire. Current Opinion in Immunology. 20: 82-8. PMID 18243675 DOI: 10.1016/J.Coi.2007.12.004  0.742
2007 Hammer GE, Shastri N. Construction and destruction of MHC class I in the peptide-loading complex. Nature Immunology. 8: 793-4. PMID 17641657 DOI: 10.1038/Ni0807-793  0.815
2007 Hammer GE, Kanaseki T, Shastri N. The final touches make perfect the peptide-MHC class I repertoire. Immunity. 26: 397-406. PMID 17459809 DOI: 10.1016/J.Immuni.2007.04.003  0.873
2007 Hammer GE, Gonzalez F, James E, Nolla H, Shastri N. In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nature Immunology. 8: 101-8. PMID 17128277 DOI: 10.1038/Ni1409  0.872
2006 Kanaseki T, Blanchard N, Hammer GE, Gonzalez F, Shastri N. ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. Immunity. 25: 795-806. PMID 17088086 DOI: 10.1016/J.Immuni.2006.09.012  0.875
2006 Shastri N. Cell biology. Peptides, scrambled and stitched. Science (New York, N.Y.). 313: 1398-9. PMID 16959995 DOI: 10.1126/Science.1132882  0.704
2006 Kunisawa J, Shastri N. Hsp90alpha chaperones large C-terminally extended proteolytic intermediates in the MHC class I antigen processing pathway. Immunity. 24: 523-34. PMID 16713971 DOI: 10.1016/J.Immuni.2006.03.015  0.606
2006 Hammer GE, Gonzalez F, Champsaur M, Cado D, Shastri N. The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nature Immunology. 7: 103-12. PMID 16299505 DOI: 10.1038/Ni1286  0.872
2005 Kwon YJ, James E, Shastri N, Fréchet JM. In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles. Proceedings of the National Academy of Sciences of the United States of America. 102: 18264-8. PMID 16344458 DOI: 10.1073/Pnas.0509541102  0.395
2005 Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunological Reviews. 207: 31-41. PMID 16181325 DOI: 10.1111/J.0105-2896.2005.00321.X  0.881
2005 Gubbels MJ, Striepen B, Shastri N, Turkoz M, Robey EA. Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii. Infection and Immunity. 73: 703-11. PMID 15664908 DOI: 10.1128/Iai.73.2.703-711.2005  0.523
2004 Standley SM, Kwon YJ, Murthy N, Kunisawa J, Shastri N, Guillaudeu SJ, Lau L, Fréchet JM. Acid-degradable particles for protein-based vaccines: enhanced survival rate for tumor-challenged mice using ovalbumin model. Bioconjugate Chemistry. 15: 1281-8. PMID 15546194 DOI: 10.1021/Bc049956F  0.328
2004 Schwab SR, Shugart JA, Horng T, Malarkannan S, Shastri N. Unanticipated antigens: translation initiation at CUG with leucine. Plos Biology. 2: e366. PMID 15510226 DOI: 10.1371/Journal.Pbio.0020366  0.829
2003 Kunisawa J, Shastri N. The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway. Molecular Cell. 12: 565-76. PMID 14527404 DOI: 10.1016/J.Molcel.2003.08.009  0.723
2003 Schwab SR, Li KC, Kang C, Shastri N. Constitutive display of cryptic translation products by MHC class I molecules. Science (New York, N.Y.). 301: 1367-71. PMID 12958358 DOI: 10.1126/Science.1085650  0.872
2003 Murthy N, Xu M, Schuck S, Kunisawa J, Shastri N, Fréchet JM. A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgels. Proceedings of the National Academy of Sciences of the United States of America. 100: 4995-5000. PMID 12704236 DOI: 10.1073/Pnas.0930644100  0.323
2003 Sahara H, Shastri N. Second class minors: molecular identification of the autosomal H46 histocompatibility locus as a peptide presented by major histocompatibility complex class II molecules. The Journal of Experimental Medicine. 197: 375-85. PMID 12566421 DOI: 10.1084/Jem.20021961  0.657
2002 Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature. 419: 480-3. PMID 12368856 DOI: 10.1038/Nature01074  0.865
2002 Furukawa H, Iizuka K, Poursine-Laurent J, Shastri N, Yokoyama WM. A ligand for the murine NK activation receptor Ly-49D: activation of tolerized NK cells from beta 2-microglobulin-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 126-36. PMID 12077237 DOI: 10.4049/Jimmunol.169.1.126  0.336
2002 Shastri N, Schwab S, Serwold T. Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annual Review of Immunology. 20: 463-93. PMID 11861610 DOI: 10.1146/Annurev.Immunol.20.100301.064819  0.875
2002 Ostrov DA, Roden MM, Shi W, Palmieri E, Christianson GJ, Mendoza L, Villaflor G, Tilley D, Shastri N, Grey H, Almo SC, Roopenian D, Nathenson SG. How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. Journal of Immunology (Baltimore, Md. : 1950). 168: 283-9. PMID 11751972 DOI: 10.4049/Jimmunol.168.1.283  0.544
2001 Brouwenstijn N, Serwold T, Shastri N. MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum Immunity. 15: 95-104. PMID 11485741 DOI: 10.1016/S1074-7613(01)00174-1  0.854
2001 Frauwirth K, Shastri N. Mutation of the invariant chain transmembrane region inhibits Ii degradation, prolongs association with MHC class II, and selectively disrupts antigen presentation Cellular Immunology. 209: 97-108. PMID 11446742 DOI: 10.1006/Cimm.2001.1796  0.42
2001 Serwold T, Gaw S, Shastri N. ER aminopeptidases generate a unique pool of peptides for MHC class I molecules. Nature Immunology. 2: 644-51. PMID 11429550 DOI: 10.1038/89800  0.85
2001 Frauwirth K, Shastri N. Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains Immunology. 102: 405-415. PMID 11328374 DOI: 10.1046/J.1365-2567.2001.01208.X  0.463
2001 Mendoza LM, Villaflor G, Eden P, Roopenian D, Shastri N. Distinguishing self from nonself: Immunogenicity of the murine H47 locus is determined by a single amino acid substitution in an unusual peptide Journal of Immunology. 166: 4438-4445. PMID 11254699 DOI: 10.4049/Jimmunol.166.7.4438  0.481
2001 Eun Young Choi, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC. Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: The H60 histocompatibility antigen dominates over all others Journal of Immunology. 166: 4370-4379. PMID 11254691 DOI: 10.4049/Jimmunol.166.7.4370  0.365
2001 Malarkannan S, Mendoza LM, Shastri N. Generation of antigen-specific, lacZ-inducible T-cell hybrids Methods in Molecular Biology (Clifton, N.J.). 156: 265-272. PMID 11068767  0.329
2001 Mendoza LM, Malarkannan S, Shastri N. Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries Methods in Molecular Biology (Clifton, N.J.). 156: 255-263. PMID 11068766  0.303
2000 Diefenbach A, Jamieson AM, Liu SD, Shastri N, Raulet DH. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nature Immunology. 1: 119-26. PMID 11248803 DOI: 10.1038/77793  0.378
2000 Malarkannan S, Horng T, Eden P, Gonzalez F, Shih P, Brouwenstijn N, Klinge H, Christianson G, Roopenian D, Shastri N. Differences that matter: Major cytotoxic T cell-stimulating minor histocompatibility antigens Immunity. 13: 333-344. PMID 11021531 DOI: 10.1016/S1074-7613(00)00033-9  0.523
2000 Schwarz K, Van Den Broek M, De Giuli R, Seelentag WW, Shastri N, Groettrup M. The use of LCMV-specific T cell hybridomas for the quantitative analysis of MHC class I restricted antigen presentation [1] Journal of Immunological Methods. 237: 199-202. PMID 10725463 DOI: 10.1016/S0022-1759(99)00236-7  0.526
2000 Campbell DJ, Serwold T, Shastri N. Bacterial proteins can be processed by macrophages in a transporter associated with antigen processing-independent, cysteine protease-dependent manner for presentation by MHC class I molecules Journal of Immunology. 164: 168-175. PMID 10605008 DOI: 10.4049/Jimmunol.164.1.168  0.859
1999 Paz P, Brouwenstijn N, Perry R, Shastri N. Discrete proteolytic intermediates in the MHC Class I antigen processing pathway and MHC I-dependent peptide trimming in the ER Immunity. 11: 241-251. PMID 10485659 DOI: 10.1016/S1074-7613(00)80099-0  0.711
1999 Wong FS, Karttunen J, Dumont C, Wen L, Visintin I, Pilip IM, Shastri N, Pamer EG, Janeway CA. Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library Nature Medicine. 5: 1026-1031. PMID 10470079 DOI: 10.1038/12465  0.425
1999 Coppola MA, Flaño E, Nguyen P, Hardy CL, Cardin RD, Shastri N, Woodland DL, Blackman MA. Apparent MHC-independent stimulation of CD8+ T cells in vivo during latent murine gammaherpesvirus infection. Journal of Immunology (Baltimore, Md. : 1950). 163: 1481-9. PMID 10415050  0.358
1999 Malarkannan S, Horng T, Shih PP, Schwab S, Shastri N. Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism Immunity. 10: 681-690. PMID 10403643 DOI: 10.1016/S1074-7613(00)80067-9  0.861
1999 Serwold T, Shastri N. Specific proteolytic cleavages limit the diversity of the pool of peptides available to MHC class I molecules in living cells Journal of Immunology. 162: 4712-4719. PMID 10202012  0.679
1998 Zuberi AR, Christianson GJ, Mendoza LM, Shastri N, Roopenian DC. Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex Immunity. 9: 687-698. PMID 9846490 DOI: 10.1016/S1074-7613(00)80666-4  0.441
1998 Malarkannan S, Shih PP, Eden PA, Horng T, Zuberi AR, Christianson G, Roopenian D, Shastri N. The molecular and functional characterization of a dominant minor H antigen, H60 Journal of Immunology. 161: 3501-3509. PMID 9759870  0.413
1998 Campbell DJ, Shastri N. Bacterial surface proteins recognized by CD4+ T cells during murine infection with Listeria monocytogenes Journal of Immunology. 161: 2339-2347. PMID 9725229  0.532
1998 Shastri N, Serwold T, Paz P. Reading within the lines: Naturally processed peptides displayed by MHC class I molecules Current Opinion in Immunology. 10: 137-144. PMID 9602301 DOI: 10.1016/S0952-7915(98)80241-0  0.863
1998 Burns RP, Natarajan K, LoCascio NJH, O'Brien DP, Kobori JA, Shastri N, Barth RK. Molecular analysis of skewed Tcra-V gene use in T-cell receptor β-chain transgenic mice Immunogenetics. 47: 107-114. PMID 9396856 DOI: 10.1007/S002510050335  0.356
1997 Mendoza LM, Paz P, Zuberi A, Christianson G, Roopenian D, Shastri N. Minors held by majors: The H13 minor histocompatibility locus defined as a peptide/MHC class I complex Immunity. 7: 461-472. PMID 9354467 DOI: 10.1016/S1074-7613(00)80368-4  0.451
1997 O'Brien DP, Baecher-Allan CM, Burns RP, Shastri N, Barth RK. Elimination of T-cell-receptor/β-chain diversity in transgenic mice restricts antigen-specific but not alloreactive responses Immunology. 91: 375-382. PMID 9301526 DOI: 10.1046/J.1365-2567.1997.00281.X  0.508
1997 Shih PP, Subramaniam M, Shastri N. Biochemical characterization of a high molecular weight thymoma antigen presented by class II MHC on third party APCs Faseb Journal. 11: A1248.  0.392
1996 Malarkannan S, Serwold T, Nguyen V, Sherman LA, Shastri N. The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class i molecule in a murine thymoma Proceedings of the National Academy of Sciences of the United States of America. 93: 13991-13996. PMID 8943048 DOI: 10.1073/Pnas.93.24.13991  0.862
1996 Malarkannan S, Gonzalez F, Nguyen V, Adair G, Shastri N. Alloreactive CD8+ T Cells Can Recognize Unusual, Rare, and Unique Processed Peptide/MHC Complexes Journal of Immunology. 157: 4464-4473. PMID 8906823  0.662
1996 Goth S, Nguyen V, Shastri N. Generation of Naturally Processed Peptide/MHC Class I Complexes Is Independent of the Stability of Endogenously Synthesized Precursors Journal of Immunology. 157: 1894-1904. PMID 8757307  0.671
1996 Shastri N. Needles in haystacks: Identifying specific peptide antigens for T cells Current Opinion in Immunology. 8: 271-277. PMID 8725951 DOI: 10.1016/S0952-7915(96)80067-7  0.758
1996 Pulaski BA, Yeh KY, Shastri N, Maltby KM, Penney DP, Lord EM, Frelinger JG. Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells Proceedings of the National Academy of Sciences of the United States of America. 93: 3669-3674. PMID 8622994 DOI: 10.1073/Pnas.93.8.3669  0.361
1995 Norbury CC, Hewlett LJ, Prescott AR, Shastri N, Watts C. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages Immunity. 3: 783-791. PMID 8777723 DOI: 10.1016/1074-7613(95)90067-5  0.575
1995 Buchholz D, Scott P, Shastri N. Presentation without proteolytic cleavage of endogenous precursors in the MHC class I antigen processing pathway Journal of Biological Chemistry. 270: 6515-6522. PMID 7896786 DOI: 10.1074/Jbc.270.12.6515  0.747
1995 Shastri N, Nguyen V, Gonzalez F. Major histocompatibility class I molecules can present cryptic translation products to T-cells Journal of Biological Chemistry. 270: 1088-1091. PMID 7836364 DOI: 10.1074/Jbc.270.3.1088  0.704
1995 Malarkannan S, Goth S, Buchholz DR, Shastri N. The role of MHC class I molecules in the generation of endogenous peptide/MHC complexes Journal of Immunology. 154: 585-598. PMID 7814870  0.695
1995 Sanderson S, Frauwirth K, Shastri N. Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins Proceedings of the National Academy of Sciences of the United States of America. 92: 7217-7221. PMID 7638170 DOI: 10.1073/Pnas.92.16.7217  0.569
1995 Shastri N, Serwold T, Gonzalez F. Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues Journal of Immunology. 155: 4339-4346. PMID 7594593  0.606
1995 Shastri N. Single T cell probes for antigen/MHC expression Current Opinion in Immunology. 7: 258-262. PMID 7546386 DOI: 10.1016/0952-7915(95)80012-3  0.469
1995 Sanderson S, Campbell DJ, Shastri N. Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning Journal of Experimental Medicine. 182: 1751-1757. PMID 7500019 DOI: 10.1084/Jem.182.6.1751  0.652
1995 Malarkannan S, Afkarian M, Shastri N. A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells Journal of Experimental Medicine. 182: 1739-1750. PMID 7500018 DOI: 10.1084/Jem.182.6.1739  0.725
1994 Sanderson S, Shastri N. LacZ inducible, antigen/MHC-specific T cell hybrids International Immunology. 6: 369-376. PMID 8186188 DOI: 10.1093/Intimm/6.3.369  0.48
1994 Negulescu PA, Shastri N, Cahalan MD. Intracellular calcium dependence of gene expression in single T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 91: 2873-7. PMID 8146203 DOI: 10.1073/Pnas.91.7.2873  0.319
1994 Manca F, Dessi V, Shastri N, Oki A, Kaplan M, Clarke J, Miller A, Sercarz EE. Isolation of lysozyme-specific T cell clones that discriminate between native and denatured antigen Cellular Immunology. 154: 420-429. PMID 8131210 DOI: 10.1006/Cimm.1994.1088  0.443
1993 Shastri N, Gonzalez F. Endogenous Generation and Presentation of the Ovalbumin Peptide/Kb Complex to T Cells1 Journal of Immunology. 150: 2724-2736. PMID 8454852  0.685
1993 Falk K, Rötzschke O, Faath S, Goth S, Graef I, Shastri N, Rammensee HG. Both Human and Mouse Cells Expressing H-2Kb and Ovalbumin Process the Same Peptide, SIINFEKL Cellular Immunology. 150: 447-452. PMID 8370082 DOI: 10.1006/Cimm.1993.1212  0.503
1992 Karttunen J, Sanderson S, Shastri N. Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens Proceedings of the National Academy of Sciences of the United States of America. 89: 6020-6024. PMID 1378619 DOI: 10.1073/Pnas.89.13.6020  0.548
1992 Kobori JA, Hood L, Shastri N. Structure-function relationship among T-cell receptors specific for lysozyme peptides bound to Ab or Abm-12 molecules Proceedings of the National Academy of Sciences of the United States of America. 89: 2940-2944. PMID 1313573 DOI: 10.1073/Pnas.89.7.2940  0.625
1992 Ettehadieh E, Sanghera JS, Pelech SL, Hess-Bienz D, Watts J, Shastri N, Aebersold R. Tyrosyl phosphorylation and activation of MAP kinases by p56lck Science. 255: 853-855. PMID 1311128 DOI: 10.1126/Science.1311128  0.348
1992 Shastri N. Antigen processing and recognition Cell. 71: 5-7. DOI: 10.1016/0092-8674(92)90260-J  0.352
1991 Karttunen J, Shastri N. Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene Proceedings of the National Academy of Sciences of the United States of America. 88: 3972-3976. PMID 1902576 DOI: 10.1073/Pnas.88.9.3972  0.461
1991 Glaichenhaus N, Shastri N, Littman DR, Turner JM. Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells Cell. 64: 511-520. PMID 1671341 DOI: 10.1016/0092-8674(91)90235-Q  0.483
1987 Gammon G, Shastri N, Cogswell J, Wilbur S, Sadegh-Nasseri S, Krzych U, Miller A, Sercarz E. The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site Immunological Reviews. 98: 53-73. PMID 2443442 DOI: 10.1111/J.1600-065X.1987.Tb00519.X  0.668
1986 Kronenberg M, Siu G, Hood LE, Shastri N. The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition Annual Review of Immunology. 4: 529-591. PMID 3518750 DOI: 10.1146/annurev.iy.04.040186.002525  0.346
1986 Malissen B, Shastri N, Pierres M, Hood L. Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule. Proceedings of the National Academy of Sciences of the United States of America. 83: 3958-62. PMID 3086873 DOI: 10.1073/Pnas.83.11.3958  0.336
1986 Shastri N, Gammon G, Miller A, Sercarz EE. Ia molecule-associated selectivity in T cell recognition of a 23-amino-acid peptide of lysozyme. The Journal of Experimental Medicine. 164: 882-96. PMID 2427637 DOI: 10.1084/Jem.164.3.882  0.721
1986 Gammon GM, Oki A, Shastri N, Sercarz EE. Induction of tolerance to one determinant on a synthetic peptide does not affect the response to a second linked determinant. Implications for the mechanism of neonatal tolerance induction. The Journal of Experimental Medicine. 164: 667-72. PMID 2425038 DOI: 10.1084/Jem.164.2.667  0.574
1986 Gammon G, Dunn K, Shastri N, Oki A, Wilbur S, Sercarz EE. Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation. Nature. 319: 413-5. PMID 2418364 DOI: 10.1038/319413A0  0.565
1985 Shastri N, Malissen B, Hood L. Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 5885-9. PMID 3875853 DOI: 10.1073/pnas.82.17.5885  0.475
1985 Shastri N, Oki A, Miller A, Sercarz EE. Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune response gene defects. The Journal of Experimental Medicine. 162: 332-45. PMID 2409209 DOI: 10.1084/Jem.162.1.332  0.615
1981 SHASTRI N, MANHAR SK, TALWAR GP. Important Role of the Carrier in the Induction of Antibody Response Without Freund's Complete Adjuvant Against a “Self” Peptide Luteinizing Hormone-Releasing Hormone (LHRH)* American Journal of Reproductive Immunology. 1: 262-265. DOI: 10.1111/j.1600-0897.1981.tb00051.x  0.329
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