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Jay Humphrey - Publications

Affiliations: 
Biomedical Engineering Yale University, New Haven, CT 
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ramachandra AB, Cavinato C, Humphrey JD. A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels. Annals of Biomedical Engineering. PMID 38227167 DOI: 10.1007/s10439-023-03432-6  0.304
2023 van Asten JGM, Latorre M, Karakaya C, Baaijens FPT, Sahlgren CM, Ristori T, Humphrey JD, Loerakker S. A multiscale computational model of arterial growth and remodeling including Notch signaling. Biomechanics and Modeling in Mechanobiology. PMID 37024602 DOI: 10.1007/s10237-023-01697-3  0.331
2023 Greaney AM, Ramachandra AB, Yuan Y, Korneva A, Humphrey JD, Niklason LE. Decellularization compromises mechanical and structural properties of the native trachea. Biomaterials and Biosystems. 9: 100074. PMID 36967724 DOI: 10.1016/j.bbiosy.2023.100074  0.301
2023 Breuer T, Jimenez M, Humphrey JD, Shinoka T, Breuer CK. Tissue Engineering of Vascular Grafts: A Case Report From Bench to Bedside and Back. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 36633008 DOI: 10.1161/ATVBAHA.122.318236  0.331
2022 Ramachandra AB, Wang H, Wnorowski A, Schwarz EL, Pickering J, Heiler JC, Lucian HJ, Hironaka CE, Tran NA, Liu Y, Khan MO, Obafemi O, Tada Y, Kahn AM, Sayed N, ... ... Humphrey JD, et al. Biodegradable external wrapping promotes favorable adaptation in an ovine vein graft model. Acta Biomaterialia. PMID 35995404 DOI: 10.1016/j.actbio.2022.08.029  0.313
2022 Loerakker S, Humphrey JD. Computer Model-Driven Design in Cardiovascular Regenerative Medicine. Annals of Biomedical Engineering. PMID 35974236 DOI: 10.1007/s10439-022-03037-5  0.318
2022 Latorre M, Szafron JM, Ramachandra AB, Humphrey JD. In vivo development of tissue engineered vascular grafts: a fluid-solid-growth model. Biomechanics and Modeling in Mechanobiology. PMID 35179675 DOI: 10.1007/s10237-022-01562-9  0.374
2022 Eberth JF, Humphrey JD. Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling. Journal of Biomechanical Engineering. 144. PMID 34729580 DOI: 10.1115/1.4052888  0.309
2021 Latorre M, Spronck B, Humphrey JD. Complementary roles of mechanotransduction and inflammation in vascular homeostasis. Proceedings. Mathematical, Physical, and Engineering Sciences. 477: 20200622. PMID 33642928 DOI: 10.1098/rspa.2020.0622  0.303
2020 Weiss D, Cavinato C, Gray A, Ramachandra AB, Avril S, Humphrey JD, Latorre M. Mechanics-driven mechanobiological mechanisms of arterial tortuosity. Science Advances. 6. PMID 33277255 DOI: 10.1126/sciadv.abd3574  0.304
2020 Zbinden JC, Blum KM, Berman AG, Ramachandra AB, Szafron JM, Kerr KE, Anderson JL, Sangha GS, Earl CC, Nigh NR, Mirhaidari GJM, Reinhardt JW, Chang YC, Yi T, Smalley R, ... ... Humphrey JD, et al. Effects of Braiding Parameters on Tissue Engineered Vascular Graft Development. Advanced Healthcare Materials. e2001093. PMID 33063452 DOI: 10.1002/adhm.202001093  0.34
2020 Wu YL, Szafron JM, Blum K, Zbinden JC, Khosravi R, Best CA, Reinhardt J, Zheng Q, Yi T, Shinoka T, Humphrey JD, Breuer CK, Wang Y. Electrospun tissue engineered arterial graft thickness affects long-term composition and mechanics. Tissue Engineering. Part A. PMID 32854586 DOI: 10.1089/Ten.Tea.2020.0166  0.351
2020 Irons L, Humphrey JD. Cell signaling model for arterial mechanobiology. Plos Computational Biology. 16: e1008161. PMID 32834001 DOI: 10.1371/journal.pcbi.1008161  0.309
2020 Drews JD, Pepper VK, Best CA, Szafron JM, Cheatham JP, Yates AR, Hor KN, Zbinden JC, Chang YC, Mirhaidari GJM, Ramachandra AB, Miyamoto S, Blum KM, Onwuka EA, Zakko J, ... ... Humphrey JD, et al. Spontaneous reversal of stenosis in tissue-engineered vascular grafts. Science Translational Medicine. 12. PMID 32238576 DOI: 10.1126/Scitranslmed.Aax6919  0.352
2020 Khosravi R, Ramachandra AB, Szafron JM, Schiavazzi DE, Breuer CK, Humphrey JD. A computational bio-chemo-mechanical model of in vivo tissue-engineered vascular graft development. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 32222759 DOI: 10.1093/Intbio/Zyaa004  0.356
2020 Eichinger JF, Paukner D, Szafron JM, Aydin RC, Humphrey J, Cyron C. Computer-Controlled Biaxial Bioreactor for Investigating Cell-Mediated Homeostasis in Tissue Equivalents. Journal of Biomechanical Engineering. PMID 32005993 DOI: 10.1115/1.4046201  0.346
2019 Szafron JM, B Ramachandra A, Breuer CK, Marsden AL, Humphrey JD. Optimization of Tissue Engineered Vascular Graft Design Using Computational Modeling. Tissue Engineering. Part C, Methods. PMID 31218941 DOI: 10.1089/Ten.Tec.2019.0086  0.345
2019 Best CA, Szafron JM, Rocco KA, Zbinden J, Dean EW, Maxfield MW, Kurobe H, Tara S, Bagi PS, Udelsman BV, Khosravi R, Yi T, Shinoka T, Humphrey JD, Breuer CK. Differential outcomes of venous and arterial tissue engineered vascular grafts highlight the importance of coupling long-term implantation studies with computational modeling. Acta Biomaterialia. PMID 31200116 DOI: 10.1016/J.Actbio.2019.05.063  0.409
2019 Spronck B, Humphrey J. Arterial Stiffness: Different Metrics, Different Meanings. Journal of Biomechanical Engineering. PMID 30985880 DOI: 10.1115/1.4043486  0.385
2018 Latorre M, Humphrey JD. Critical roles of time-scales in soft tissue growth and remodeling. Apl Bioengineering. 2: 026108. PMID 31069305 DOI: 10.1063/1.5017842  0.303
2018 Szafron JM, Khosravi R, Reinhardt J, Best CA, Bersi MR, Yi T, Breuer CK, Humphrey JD. Immuno-driven and Mechano-mediated Neotissue Formation in Tissue Engineered Vascular Grafts. Annals of Biomedical Engineering. PMID 29987541 DOI: 10.1007/S10439-018-2086-7  0.335
2018 Best CA, Fukunishi T, Drews J, Khosravi R, Hor K, Mahler N, Yi T, Humphrey JD, Johnson J, Breuer CK, Hibino N. Oversized biodegradable arterial grafts promote enhanced neointimal tissue formation. Tissue Engineering. Part A. PMID 29431029 DOI: 10.1089/Ten.Tea.2017.0483  0.348
2018 Bersi MR, Khosravi R, Wujciak AJ, Harrison DG, Humphrey JD. Differential cell-matrix mechanoadaptations and inflammation drive regional propensities to aortic fibrosis, aneurysm or dissection in hypertension. Journal of the Royal Society, Interface. 14. PMID 29118111 DOI: 10.1098/Rsif.2017.0327  0.305
2017 Szafron JM, Breuer C, Wang Y, Humphrey J. Stress Analysis-Driven Design of Bilayered Scaffolds for Tissue Engineered Vascular Grafts. Journal of Biomechanical Engineering. PMID 28886204 DOI: 10.1115/1.4037856  0.362
2016 Khosravi R, Best CA, Allen RA, Stowell CE, Onwuka E, Zhuang JJ, Lee YU, Yi T, Bersi MR, Shinoka T, Humphrey JD, Wang Y, Breuer CK. Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice. Annals of Biomedical Engineering. PMID 26795977 DOI: 10.1007/S10439-015-1545-7  0.317
2015 Khosravi R, Miller KS, Best CA, Shih YC, Lee YU, Yi T, Shinoka T, Breuer CK, Humphrey JD. Biomechanical diversity despite mechanobiological stability in tissue engineered vascular grafts two years post-implantation. Tissue Engineering. Part A. 21: 1529-38. PMID 25710791 DOI: 10.1089/Ten.Tea.2014.0524  0.584
2015 Huang AH, Lee YU, Calle EA, Boyle M, Starcher BC, Humphrey JD, Niklason LE. Design and Use of a Novel Bioreactor for Regeneration of Biaxially Stretched Tissue-Engineered Vessels. Tissue Engineering. Part C, Methods. 21: 841-51. PMID 25669988 DOI: 10.1089/ten.TEC.2014.0287  0.355
2015 Sorrentino TA, Fourman L, Ferruzzi J, Miller KS, Humphrey JD, Roccabianca S. Local versus global mechanical effects of intramural swelling in carotid arteries. Journal of Biomechanical Engineering. 137: 041008. PMID 25474096 DOI: 10.1115/1.4029303  0.534
2015 Miller KS, Khosravi R, Breuer CK, Humphrey JD. A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation. Acta Biomaterialia. 11: 283-94. PMID 25288519 DOI: 10.1016/J.Actbio.2014.09.046  0.563
2014 Udelsman BV, Khosravi R, Miller KS, Dean EW, Bersi MR, Rocco K, Yi T, Humphrey JD, Breuer CK. Characterization of evolving biomechanical properties of tissue engineered vascular grafts in the arterial circulation. Journal of Biomechanics. 47: 2070-9. PMID 24702863 DOI: 10.1016/J.Jbiomech.2014.03.011  0.599
2014 Miller KS, Lee YU, Naito Y, Breuer CK, Humphrey JD. Computational model of the in vivo development of a tissue engineered vein from an implanted polymeric construct. Journal of Biomechanics. 47: 2080-7. PMID 24210474 DOI: 10.1016/J.Jbiomech.2013.10.009  0.58
2014 Bellini C, Ferruzzi J, Roccabianca S, Di Martino ES, Humphrey JD. A microstructurally motivated model of arterial wall mechanics with mechanobiological implications. Annals of Biomedical Engineering. 42: 488-502. PMID 24197802 DOI: 10.1007/S10439-013-0928-X  0.314
2014 Naito Y, Lee YU, Yi T, Church SN, Solomon D, Humphrey JD, Shin'oka T, Breuer CK. Beyond burst pressure: initial evaluation of the natural history of the biaxial mechanical properties of tissue-engineered vascular grafts in the venous circulation using a murine model. Tissue Engineering. Part A. 20: 346-55. PMID 23957852 DOI: 10.1089/Ten.Tea.2012.0613  0.381
2013 Lee YU, Naito Y, Kurobe H, Breuer CK, Humphrey JD. Biaxial mechanical properties of the inferior vena cava in C57BL/6 and CB-17 SCID/bg mice. Journal of Biomechanics. 46: 2277-82. PMID 23859752 DOI: 10.1016/J.Jbiomech.2013.06.013  0.36
2013 Ferruzzi J, Bersi MR, Humphrey JD. Biomechanical phenotyping of central arteries in health and disease: advantages of and methods for murine models. Annals of Biomedical Engineering. 41: 1311-30. PMID 23549898 DOI: 10.1007/s10439-013-0799-1  0.306
2013 Miller KS, Udelsman BV, Lee YU, Naito Y, Breuer CK, Humphrey JD. Computational growth and remodeling model for evolving tissue engineered vascular grafts in the venous circulation Asme 2013 Conference On Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, Fmd 2013. DOI: 10.1115/FMD2013-16168  0.573
2010 Baek S, Humphrey JD. Computational modeling of growth and remodeling in biological soft tissues: Application to arterial mechanics Computational Modeling in Biomechanics. 253-274. DOI: 10.1007/978-90-481-3575-2_8  0.351
2009 Valentín A, Humphrey JD. Parameter sensitivity study of a constrained mixture model of arterial growth and remodeling. Journal of Biomechanical Engineering. 131: 101006. PMID 19831476 DOI: 10.1115/1.3192144  0.303
2009 Valentín A, Humphrey JD. Evaluation of fundamental hypotheses underlying constrained mixture models of arterial growth and remodelling. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 3585-606. PMID 19657012 DOI: 10.1098/rsta.2009.0113  0.313
2009 Valentín A, Humphrey JD. Modeling effects of axial extension on arterial growth and remodeling. Medical & Biological Engineering & Computing. 47: 979-87. PMID 19649667 DOI: 10.1007/s11517-009-0513-5  0.331
2008 Dahl SL, Vaughn ME, Hu JJ, Driessen NJ, Baaijens FP, Humphrey JD, Niklason LE. A microstructurally motivated model of the mechanical behavior of tissue engineered blood vessels. Annals of Biomedical Engineering. 36: 1782-92. PMID 18720007 DOI: 10.1007/S10439-008-9554-4  0.336
2008 Alford PW, Humphrey JD, Taber LA. Growth and remodeling in a thick-walled artery model: effects of spatial variations in wall constituents. Biomechanics and Modeling in Mechanobiology. 7: 245-62. PMID 17786493 DOI: 10.1007/S10237-007-0101-2  0.325
2004 Gleason RL, Humphrey JD. A mixture model of arterial growth and remodeling in hypertension: altered muscle tone and tissue turnover. Journal of Vascular Research. 41: 352-63. PMID 15353893 DOI: 10.1159/000080699  0.308
2004 Gleason RL, Hu JJ, Humphrey JD. Building a functional artery: issues from the perspective of mechanics. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2045-55. PMID 15353269  0.365
2002 Humphrey J, Epstein M. Cardiovascular Solid Mechanics: Cells, Tissues, and Organs Applied Mechanics Reviews. 55: B103-B104. DOI: 10.1115/1.1497492  0.354
2000 Humphrey JD. Remodeling of a collagenous tissue at fixed lengths. Journal of Biomechanical Engineering. 121: 591-7. PMID 10633258 DOI: 10.1115/1.2800858  0.3
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