Eleftheria Maratos-Flier - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Hypothalamic regulation of central and systemic function related to energy balance

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Watanabe M, Singhal G, Fisher FM, Beck TC, Morgan DA, Socciarelli F, Mather ML, Risi R, Bourke J, Rahmouni K, McGuinness OP, Flier JS, Maratos-Flier E. Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis. Endocrine. PMID 31728756 DOI: 10.1007/S12020-019-02124-3  0.377
2019 Chee MJ, Hebert AJ, Briançon N, Flaherty SE, Pissios P, Maratos-Flier E. Conditional deletion of melanin-concentrating hormone receptor 1 from GABAergic neurons increases locomotor activity. Molecular Metabolism. 29: 114-123. PMID 31668382 DOI: 10.1016/J.Molmet.2019.08.018  0.332
2018 Singhal G, Kumar G, Chan S, Fisher FM, Ma Y, Vardeh HG, Nasser IA, Flier JS, Maratos-Flier E. Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet. Molecular Metabolism. PMID 29753678 DOI: 10.1016/J.Molmet.2018.03.002  0.355
2017 Ter Horst KW, Gilijamse PW, Demirkiran A, van Wagensveld BA, Ackermans MT, Verheij J, Romijn JA, Nieuwdorp M, Maratos-Flier E, Herman MA, Serlie MJ. The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans. Molecular Metabolism. 6: 1493-1502. PMID 29107295 DOI: 10.1016/J.Molmet.2017.08.014  0.403
2017 Desai BN, Singhal G, Watanabe M, Stevanovic D, Lundasen T, Fisher FM, Mather ML, Vardeh HG, Douris N, Adams AC, Nasser IA, FitzGerald GA, Flier JS, Skarke C, Maratos-Flier E. Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury. Molecular Metabolism. 6: 1395-1406. PMID 29107287 DOI: 10.1016/J.Molmet.2017.08.004  0.317
2017 Douris N, Desai BN, Fisher FM, Cisu T, Fowler AJ, Zarebidaki E, Nguyen NLT, Morgan DA, Bartness TJ, Rahmouni K, Flier JS, Maratos-Flier E. Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice. Molecular Metabolism. 6: 854-862. PMID 28752049 DOI: 10.1016/J.Molmet.2017.05.017  0.446
2017 Flier JS, Maratos-Flier E. Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes? Cell Metabolism. 26: 24-26. PMID 28648981 DOI: 10.1016/J.Cmet.2017.05.013  0.431
2017 Maratos-Flier E. Fatty liver and FGF21 physiology. Experimental Cell Research. 360: 2-5. PMID 28549912 DOI: 10.1016/J.Yexcr.2017.05.006  0.35
2017 Fisher FM, Kim M, Doridot L, Cunniff JC, Parker TS, Levine DM, Hellerstein MK, Hudgins LC, Maratos-Flier E, Herman MA. A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism. Molecular Metabolism. 6: 14-21. PMID 28123933 DOI: 10.1016/J.Molmet.2016.11.008  0.376
2016 Shenoy VK, Beaver KM, Fisher FM, Singhal G, Dushay JR, Maratos-Flier E, Flier SN. Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis. Plos One. 11: e0164351. PMID 27832059 DOI: 10.1371/Journal.Pone.0164351  0.329
2016 Singhal G, Douris N, Fish AJ, Zhang X, Adams AC, Flier JS, Pissios P, Maratos-Flier E. Fibroblast growth factor 21 has no direct role in regulating fertility in female mice. Molecular Metabolism. 5: 690-8. PMID 27656406 DOI: 10.1016/J.Molmet.2016.05.010  0.405
2016 Lynch L, Hogan AE, Duquette D, Lester C, Banks A, LeClair K, Cohen DE, Ghosh A, Lu B, Corrigan M, Stevanovic D, Maratos-Flier E, Drucker DJ, O'Shea D, Brenner M. iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy. Cell Metabolism. PMID 27593966 DOI: 10.1016/J.Cmet.2016.08.003  0.434
2016 Singhal G, Fisher FM, Chee MJ, Tan TG, El Ouaamari A, Adams AC, Najarian R, Kulkarni RN, Benoist C, Flier JS, Maratos-Flier E. Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas. Plos One. 11: e0148252. PMID 26872145 DOI: 10.1371/Journal.Pone.0148252  0.416
2015 Fisher FM, Maratos-Flier E. Understanding the Physiology of FGF21. Annual Review of Physiology. PMID 26654352 DOI: 10.1146/Annurev-Physiol-021115-105339  0.45
2015 Domouzoglou EM, Naka KK, Vlahos AP, Papafaklis MI, Michalis LK, Tsatsoulis A, Maratos-Flier E. Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1029-38. PMID 26232236 DOI: 10.1152/Ajpheart.00527.2015  0.321
2015 Douris N, Melman T, Pecherer JM, Pissios P, Flier JS, Cantley LC, Locasale JW, Maratos-Flier E. Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet. Biochimica Et Biophysica Acta. 1852: 2056-65. PMID 26170063 DOI: 10.1016/J.Bbadis.2015.07.009  0.444
2015 Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P. Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nature Medicine. PMID 26168293 DOI: 10.1038/Nm.3882  0.383
2015 Chee MJ, Douris N, Forrow AB, Monnard A, Lu S, Flaherty SE, Adams AC, Maratos-Flier E. Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 1808-16. PMID 26092201 DOI: 10.1016/J.Euroneuro.2015.05.010  0.38
2015 Carracedo A, Rousseau D, Douris N, Fernández-Ruiz S, Martín-Martín N, Weiss D, Webster K, Adams AC, Vazquez-Chantada M, Martinez-Chantar ML, Anty R, Tran A, Maratos-Flier E, Gual P, Pandolfi PP. The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis. International Journal of Biological Sciences. 11: 629-32. PMID 25999785 DOI: 10.7150/Ijbs.11615  0.432
2015 Douris N, Stevanovic DM, Fisher FM, Cisu TI, Chee MJ, Nguyen NL, Zarebidaki E, Adams AC, Kharitonenkov A, Flier JS, Bartness TJ, Maratos-Flier E. Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice. Endocrinology. 156: 2470-81. PMID 25924103 DOI: 10.1210/En.2014-2001  0.413
2015 Dushay JR, Toschi E, Mitten EK, Fisher FM, Herman MA, Maratos-Flier E. Fructose ingestion acutely stimulates circulating FGF21 levels in humans. Molecular Metabolism. 4: 51-7. PMID 25685689 DOI: 10.1016/J.Molmet.2014.09.008  0.358
2014 Fisher FM, Chui PC, Nasser IA, Popov Y, Cunniff JC, Lundasen T, Kharitonenkov A, Schuppan D, Flier JS, Maratos-Flier E. Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets. Gastroenterology. 147: 1073-83.e6. PMID 25083607 DOI: 10.1053/J.Gastro.2014.07.044  0.426
2014 Domouzoglou EM, Fisher FM, Astapova I, Fox EC, Kharitonenkov A, Flier JS, Hollenberg AN, Maratos-Flier E. Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo. Endocrinology. 155: 2031-40. PMID 24564398 DOI: 10.1210/En.2013-1902  0.418
2014 Chee MJ, Pissios P, Prasad D, Maratos-Flier E. Expression of melanin-concentrating hormone receptor 2 protects against diet-induced obesity in male mice. Endocrinology. 155: 81-8. PMID 24169555 DOI: 10.1210/En.2013-1738  0.476
2013 Pissios P, Hong S, Kennedy AR, Prasad D, Liu FF, Maratos-Flier E. Methionine and choline regulate the metabolic phenotype of a ketogenic diet. Molecular Metabolism. 2: 306-13. PMID 24049742 DOI: 10.1016/J.Molmet.2013.07.003  0.401
2013 Chee MJ, Pissios P, Maratos-Flier E. Neurochemical characterization of neurons expressing melanin-concentrating hormone receptor 1 in the mouse hypothalamus. The Journal of Comparative Neurology. 521: 2208-34. PMID 23605441 DOI: 10.1002/Cne.23273  0.385
2013 Suzuki R, Ferris HA, Chee MJ, Maratos-Flier E, Kahn CR. Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function. Plos Biology. 11: e1001532. PMID 23585733 DOI: 10.1371/Journal.Pbio.1001532  0.311
2013 Dai Y, Kiselak T, Clark J, Clore E, Zheng K, Cheng A, Kujoth GC, Prolla TA, Maratos-Flier E, Simon DK. Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion. 13: 282-91. PMID 23542163 DOI: 10.1016/J.Mito.2013.03.006  0.303
2013 Fisher FM, Maratos-Flier E. Stress heats up the adipocyte. Nature Medicine. 19: 17-8. PMID 23296001 DOI: 10.1038/Nm.3058  0.309
2012 Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, Wu J, Kharitonenkov A, Flier JS, Maratos-Flier E, Spiegelman BM. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes & Development. 26: 271-81. PMID 22302939 DOI: 10.1101/Gad.177857.111  0.384
2012 Tschöp MH, Speakman JR, Arch JR, Auwerx J, Brüning JC, Chan L, Eckel RH, Farese RV, Galgani JE, Hambly C, Herman MA, Horvath TL, Kahn BB, Kozma SC, Maratos-Flier E, et al. A guide to analysis of mouse energy metabolism. Nature Methods. 9: 57-63. PMID 22205519 DOI: 10.1038/Nmeth.1806  0.316
2012 McNay DE, Briançon N, Kokoeva MV, Maratos-Flier E, Flier JS. Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice. The Journal of Clinical Investigation. 122: 142-52. PMID 22201680 DOI: 10.1172/Jci43134  0.407
2012 Dushay J, Gao C, Gopalakrishnan GS, Crawley M, Mitten EK, Wilker E, Mullington J, Maratos-Flier E. Short-term exenatide treatment leads to significant weight loss in a subset of obese women without diabetes. Diabetes Care. 35: 4-11. PMID 22040840 DOI: 10.2337/Dc11-0931  0.304
2011 Vella KR, Ramadoss P, Lam FS, Harris JC, Ye FD, Same PD, O'Neill NF, Maratos-Flier E, Hollenberg AN. NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways. Cell Metabolism. 14: 780-90. PMID 22100407 DOI: 10.1016/J.Cmet.2011.10.009  0.399
2011 Fisher FM, Estall JL, Adams AC, Antonellis PJ, Bina HA, Flier JS, Kharitonenkov A, Spiegelman BM, Maratos-Flier E. Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo. Endocrinology. 152: 2996-3004. PMID 21712364 DOI: 10.1210/En.2011-0281  0.433
2011 Krashes MJ, Koda S, Ye C, Rogan SC, Adams AC, Cusher DS, Maratos-Flier E, Roth BL, Lowell BB. Rapid, reversible activation of AgRP neurons drives feeding behavior in mice. The Journal of Clinical Investigation. 121: 1424-8. PMID 21364278 DOI: 10.1172/Jci46229  0.35
2011 Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED. Transcriptional control of adipose lipid handling by IRF4. Cell Metabolism. 13: 249-59. PMID 21356515 DOI: 10.1016/J.Cmet.2011.02.005  0.406
2011 Domouzoglou EM, Maratos-Flier E. Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis. The American Journal of Clinical Nutrition. 93: 901S-5. PMID 21346090 DOI: 10.3945/Ajcn.110.001941  0.457
2011 Aboulaich N, Chui PC, Asara JM, Flier JS, Maratos-Flier E. Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism. Diabetes. 60: 757-65. PMID 21282370 DOI: 10.2337/Db10-0744  0.391
2011 Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J, Horner JW, Maratos-Flier E, Depinho RA. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 469: 102-6. PMID 21113150 DOI: 10.1038/Nature09603  0.332
2010 Flier JS, Maratos-Flier E. Lasker lauds leptin. Cell Metabolism. 12: 317-20. PMID 20889124 DOI: 10.1016/J.Cmet.2010.09.008  0.351
2010 Flier JS, Maratos-Flier E. Lasker lauds leptin. Cell. 143: 9-12. PMID 20887884 DOI: 10.1016/J.Cell.2010.09.021  0.358
2010 Briancon N, McNay DE, Maratos-Flier E, Flier JS. Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance. Diabetes. 59: 3074-84. PMID 20876718 DOI: 10.2337/Db10-0481  0.424
2010 Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, Maratos-Flier E. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes. 59: 2781-9. PMID 20682689 DOI: 10.2337/Db10-0193  0.452
2010 Shapiro NI, Khankin EV, Van Meurs M, Shih SC, Lu S, Yano M, Castro PR, Maratos-Flier E, Parikh SM, Karumanchi SA, Yano K. Leptin exacerbates sepsis-mediated morbidity and mortality. Journal of Immunology (Baltimore, Md. : 1950). 185: 517-24. PMID 20519646 DOI: 10.4049/Jimmunol.0903975  0.388
2010 Dushay J, Chui PC, Gopalakrishnan GS, Varela-Rey M, Crawley M, Fisher FM, Badman MK, Martinez-Chantar ML, Maratos-Flier E. Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology. 139: 456-63. PMID 20451522 DOI: 10.1053/J.Gastro.2010.04.054  0.411
2010 Adams AC, Astapova I, Fisher FM, Badman MK, Kurgansky KE, Flier JS, Hollenberg AN, Maratos-Flier E. Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner. The Journal of Biological Chemistry. 285: 14078-82. PMID 20236931 DOI: 10.1074/Jbc.C110.107375  0.397
2010 Glier MB, Pissios P, Babich SL, Macdonald ML, Hayden MR, Maratos-Flier E, Gibson WT. The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone. Peptides. 31: 123-9. PMID 19883709 DOI: 10.1016/J.Peptides.2009.10.018  0.413
2009 Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proceedings of the National Academy of Sciences of the United States of America. 106: 22510-5. PMID 20018698 DOI: 10.1073/Pnas.0912533106  0.357
2009 Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology. 150: 4931-40. PMID 19819944 DOI: 10.1210/En.2009-0532  0.459
2009 Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E. A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss. American Journal of Physiology. Endocrinology and Metabolism. 297: E1197-204. PMID 19738035 DOI: 10.1152/Ajpendo.00357.2009  0.477
2009 Patti ME, Houten SM, Bianco AC, Bernier R, Larsen PR, Holst JJ, Badman MK, Maratos-Flier E, Mun EC, Pihlajamaki J, Auwerx J, Goldfine AB. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring, Md.). 17: 1671-7. PMID 19360006 DOI: 10.1038/Oby.2009.102  0.319
2009 Zhang R, Maratos-Flier E, Flier JS. Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B. Endocrinology. 150: 3076-82. PMID 19359377 DOI: 10.1210/En.2009-0108  0.444
2009 Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. A high-fat, ketogenic diet induces a unique metabolic state in mice (American Journal of Physiology - Endocrinology and Metabolism (2007) 292, 55, (E1724-E1739)) American Journal of Physiology - Endocrinology and Metabolism. 296: E1179. DOI: 10.1152/Ajpendo.Zh1-05678-Corr-2009  0.351
2008 Willie JT, Sinton CM, Maratos-Flier E, Yanagisawa M. Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression. Neuroscience. 156: 819-29. PMID 18809470 DOI: 10.1016/J.Neuroscience.2008.08.048  0.329
2008 Zhang R, Dhillon H, Yin H, Yoshimura A, Lowell BB, Maratos-Flier E, Flier JS. Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight. Endocrinology. 149: 5654-61. PMID 18669597 DOI: 10.1210/En.2008-0805  0.445
2008 Kokkotou E, Moss AC, Torres D, Karagiannides I, Cheifetz A, Liu S, O'Brien M, Maratos-Flier E, Pothoulakis C. Melanin-concentrating hormone as a mediator of intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America. 105: 10613-8. PMID 18650383 DOI: 10.1073/Pnas.0804536105  0.368
2008 Bradley RL, Jeon JY, Liu FF, Maratos-Flier E. Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice. American Journal of Physiology. Endocrinology and Metabolism. 295: E586-94. PMID 18577694 DOI: 10.1152/Ajpendo.00309.2007  0.364
2008 Maratos-Flier E. The long reach of leptin. Nature Medicine. 14: 604-6. PMID 18535571 DOI: 10.1038/Nm0608-604  0.32
2008 Bradley RL, Fisher FF, Maratos-Flier E. Dietary fatty acids differentially regulate production of TNF-alpha and IL-10 by murine 3T3-L1 adipocytes. Obesity (Silver Spring, Md.). 16: 938-44. PMID 18356844 DOI: 10.1038/Oby.2008.39  0.3
2008 Pissios P, Frank L, Kennedy AR, Porter DR, Marino FE, Liu FF, Pothos EN, Maratos-Flier E. Dysregulation of the mesolimbic dopamine system and reward in MCH-/- mice. Biological Psychiatry. 64: 184-91. PMID 18281019 DOI: 10.1016/J.Biopsych.2007.12.011  0.356
2007 Katic M, Kennedy AR, Leykin I, Norris A, McGettrick A, Gesta S, Russell SJ, Bluher M, Maratos-Flier E, Kahn CR. Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice. Aging Cell. 6: 827-39. PMID 18001293 DOI: 10.1111/J.1474-9726.2007.00346.X  0.421
2007 Pissios P, Maratos-Flier E. More than satiety: central serotonin signaling and glucose homeostasis. Cell Metabolism. 6: 345-7. PMID 17983579 DOI: 10.1016/J.Cmet.2007.10.009  0.312
2007 Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metabolism. 5: 426-37. PMID 17550778 DOI: 10.1016/J.Cmet.2007.05.002  0.391
2007 Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. A high-fat, ketogenic diet induces a unique metabolic state in mice. American Journal of Physiology. Endocrinology and Metabolism. 292: E1724-39. PMID 17299079 DOI: 10.1152/Ajpendo.00717.2006  0.429
2007 Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN. Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes. 56: 311-9. PMID 17259374 DOI: 10.2337/Db06-0708  0.411
2007 Kennedy AR, Pissios P, Otu HH, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. Erratum: A high-fat, ketogenic diet induces a unique metabolic state in mice (American Journal of Physiology - Endocrinology and Metabolism doi 10.1152/ajpendo.00717.2006) American Journal of Physiology-Endocrinology and Metabolism. 293. DOI: 10.1152/Ajpendo.Zh1-5191-Corr.2007  0.371
2006 Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron. 51: 811-22. PMID 16982425 DOI: 10.1016/J.Neuron.2006.09.006  0.382
2006 Pissios P, Bradley RL, Maratos-Flier E. Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions. Endocrine Reviews. 27: 606-20. PMID 16788162 DOI: 10.1210/Er.2006-0021  0.324
2006 Jeon JY, Bradley RL, Kokkotou EG, Marino FE, Wang X, Pissios P, Maratos-Flier E. MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance. Diabetes. 55: 428-34. PMID 16443777 DOI: 10.2337/Diabetes.55.02.06.Db05-0203  0.361
2005 Georgescu D, Sears RM, Hommel JD, Barrot M, Bolaños CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2933-40. PMID 15772353 DOI: 10.1523/Jneurosci.1714-04.2005  0.355
2005 Kokkotou E, Jeon JY, Wang X, Marino FE, Carlson M, Trombly DJ, Maratos-Flier E. Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R117-24. PMID 15731402 DOI: 10.1152/Ajpregu.00861.2004  0.42
2004 Bates SH, Dundon TA, Seifert M, Carlson M, Maratos-Flier E, Myers MG. LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin. Diabetes. 53: 3067-73. PMID 15561935 DOI: 10.2337/Diabetes.53.12.3067  0.428
2004 Blüher S, Moschos S, Bullen J, Kokkotou E, Maratos-Flier E, Wiegand SJ, Sleeman MW, Sleemann MW, Mantzoros CS. Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice. Diabetes. 53: 2787-96. PMID 15504958 DOI: 10.2337/Diabetes.53.11.2787  0.455
2004 Bullen JW, Ziotopoulou M, Ungsunan L, Misra J, Alevizos I, Kokkotou E, Maratos-Flier E, Stephanopoulos G, Mantzoros CS. Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides. American Journal of Physiology. Endocrinology and Metabolism. 287: E662-70. PMID 15361355 DOI: 10.1152/Ajpendo.00114.2004  0.443
2004 Gibson WT, Pissios P, Trombly DJ, Luan J, Keogh J, Wareham NJ, Maratos-Flier E, O'Rahilly S, Farooqi IS. Melanin-concentrating hormone receptor mutations and human obesity: functional analysis. Obesity Research. 12: 743-9. PMID 15166293 DOI: 10.1038/Oby.2004.89  0.392
2004 Tritos NA, Segal-Lieberman G, Vezeridis PS, Maratos-Flier E. Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone. Obesity Research. 12: 716-24. PMID 15090642 DOI: 10.1038/Oby.2004.84  0.386
2004 Blüher S, Ziotopoulou M, Bullen JW, Moschos SJ, Ungsunan L, Kokkotou E, Maratos-Flier E, Mantzoros CS. Responsiveness to peripherally administered melanocortins in lean and obese mice. Diabetes. 53: 82-90. PMID 14693701 DOI: 10.2337/Diabetes.53.1.82  0.461
2003 Tritos NA, Mun E, Bertkau A, Grayson R, Maratos-Flier E, Goldfine A. Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery. Obesity Research. 11: 919-24. PMID 12917494 DOI: 10.1038/Oby.2003.126  0.328
2003 Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG, Flier JS, Maratos-Flier E. Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype. Proceedings of the National Academy of Sciences of the United States of America. 100: 10085-90. PMID 12897241 DOI: 10.1073/Pnas.1633636100  0.469
2003 Pissios P, Maratos-Flier E. Melanin-concentrating hormone: from fish skin to skinny mammals. Trends in Endocrinology and Metabolism: Tem. 14: 243-8. PMID 12826331 DOI: 10.1016/S1043-2760(03)00079-1  0.444
2003 Tritos NA, Kokkinos A, Lampadariou E, Alexiou E, Katsilambros N, Maratos-Flier E. Cerebrospinal fluid ghrelin is negatively associated with body mass index. The Journal of Clinical Endocrinology and Metabolism. 88: 2943-6. PMID 12788909 DOI: 10.1210/Jc.2003-030300  0.358
2003 Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature. 421: 856-9. PMID 12594516 DOI: 10.1038/Nature01388  0.431
2003 Segal-Lieberman G, Trombly DJ, Juthani V, Wang X, Maratos-Flier E. NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting. American Journal of Physiology. Endocrinology and Metabolism. 284: E1131-9. PMID 12582011 DOI: 10.1152/Ajpendo.00491.2002  0.45
2003 Tritos NA, Mastaitis JW, Kokkotou EG, Puigserver P, Spiegelman BM, Maratos-Flier E. Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain. Brain Research. 961: 255-60. PMID 12531492 DOI: 10.1016/S0006-8993(02)03961-6  0.336
2002 Bradley RL, Mansfield JP, Maratos-Flier E, Cheatham B. Melanin-concentrating hormone activates signaling pathways in 3T3-L1 adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 283: E584-92. PMID 12169453 DOI: 10.1152/Ajpendo.00161.2002  0.32
2002 Flier JS, Maratos-Flier E. The stomach speaks--ghrelin and weight regulation. The New England Journal of Medicine. 346: 1662-3. PMID 12024001 DOI: 10.1056/Nejm200205233462112  0.352
2001 Tritos NA, Mastaitis JW, Kokkotou E, Maratos-Flier E. Characterization of melanin concentrating hormone and preproorexin expression in the murine hypothalamus. Brain Research. 895: 160-6. PMID 11259773 DOI: 10.1016/S0006-8993(01)02066-2  0.459
2001 Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. The Journal of Clinical Investigation. 107: 379-86. PMID 11160162 DOI: 10.1172/Jci10660  0.454
2001 Kokkotou EG, Tritos NA, Mastaitis JW, Slieker L, Maratos-Flier E. Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain. Endocrinology. 142: 680-6. PMID 11159839 DOI: 10.1210/Endo.142.2.7981  0.328
2000 Bradley RL, Kokkotou EG, Maratos-Flier E, Cheatham B. Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes. Diabetes. 49: 1073-7. PMID 10909960 DOI: 10.2337/Diabetes.49.7.1073  0.418
2000 Vicent D, Maratos-Flier E, Kahn CR. The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis. Molecular and Cellular Biology. 20: 2158-66. PMID 10688662 DOI: 10.1128/Mcb.20.6.2158-2166.2000  0.383
1999 Tritos NA, Maratos-Flier E. Two important systems in energy homeostasis: melanocortins and melanin-concentrating hormone. Neuropeptides. 33: 339-49. PMID 10657511 DOI: 10.1054/Npep.1999.0055  0.364
1998 Elmquist JK, Maratos-Flier E, Saper CB, Flier JS. Unraveling the central nervous system pathways underlying responses to leptin. Nature Neuroscience. 1: 445-50. PMID 10196541 DOI: 10.1038/2164  0.431
1998 Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. 396: 670-4. PMID 9872314 DOI: 10.1038/25341  0.466
1998 Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. The Journal of Comparative Neurology. 402: 442-59. PMID 9862320 DOI: 10.1002/(Sici)1096-9861(19981228)402:4<442::Aid-Cne2>3.0.Co;2-R  0.345
1998 Tritos NA, Elmquist JK, Mastaitis JW, Flier JS, Maratos-Flier E. Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice. Endocrinology. 139: 4634-41. PMID 9794475 DOI: 10.1210/Endo.139.11.6308  0.452
1998 Tritos NA, Vicent D, Gillette J, Ludwig DS, Flier ES, Maratos-Flier E. Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus. Diabetes. 47: 1687-92. PMID 9792536 DOI: 10.2337/Diabetes.47.11.1687  0.307
1998 Vicent D, Piper M, Gammeltoft S, Maratos-Flier E, Kahn CR. Alterations in skeletal muscle gene expression of ob/ob mice by mRNA differential display. Diabetes. 47: 1451-8. PMID 9726234 DOI: 10.2337/Diabetes.47.9.1451  0.335
1998 Maratos-Flier E. Reovirus and endocrine cells. Current Topics in Microbiology and Immunology. 233: 85-91. PMID 9599933 DOI: 10.1007/978-3-642-72095-6_5  0.301
1998 Mantzoros CS, Frederich RC, Qu D, Lowell BB, Maratos-Flier E, Flier JS. Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations Diabetes. 47: 230-238. PMID 9519718 DOI: 10.2337/Diab.47.2.230  0.459
1998 Flier JS, Maratos-Flier E. Obesity and the hypothalamus: Novel peptides for new pathways Cell. 92: 437-440. PMID 9491885 DOI: 10.1016/S0092-8674(00)80937-X  0.357
1997 Maratos-Flier E, Qu D, Gammeltoft S. Analysis of gene expression in hypothalamus in obese and normal mice using differential display Methods in Molecular Biology (Clifton, N.J.). 85: 297-304. PMID 9276333 DOI: 10.1385/0-89603-489-5:297  0.398
1997 Elmquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB. Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology. 138: 839-42. PMID 9003024 DOI: 10.1210/Endo.138.2.5033  0.348
1996 Ahlma RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS. Role of leptin in the neuroendocrine response to fasting Nature. 382: 250-252. PMID 8717038 DOI: 10.1038/382250A0  0.475
1996 Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, Cullen MJ, Mathes WF, Przypek R, Kanarek R, Maratos-Flier E. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature. 380: 243-7. PMID 8637571 DOI: 10.1016/0167-0115(96)88033-5  0.453
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