Jørgen Kjems - Publications

Affiliations: 
2008-2013 Nanoscience Aarhus University, Aarhus, Denmark 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Thomsen RP, Sørensen RS, Kjems J. Parallel Functionalization of DNA Origami. Methods in Molecular Biology (Clifton, N.J.). 2639: 175-194. PMID 37166718 DOI: 10.1007/978-1-0716-3028-0_11  0.751
2023 Chen LL, Bindereif A, Bozzoni I, Chang HY, Matera AG, Gorospe M, Hansen TB, Kjems J, Ma XK, Pek JW, Rajewsky N, Salzman J, Wilusz JE, Yang L, Zhao F. A guide to naming eukaryotic circular RNAs. Nature Cell Biology. PMID 36658223 DOI: 10.1038/s41556-022-01066-9  0.638
2022 Khateb H, Sørensen RS, Cramer K, Eklund AS, Kjems J, Meyer RL, Jungmann R, Sutherland DS. The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Studied by Protein Patterning and DNA-PAINT. Acs Nano. PMID 35801826 DOI: 10.1021/acsnano.2c00630  0.739
2020 Kirkegaard K, Yan Y, Sørensen BS, Hardarson T, Hanson C, Ingerslev HJ, Knudsen UB, Kjems J, Lundin K, Ahlström A. Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid. Journal of Assisted Reproduction and Genetics. PMID 32681282 DOI: 10.1007/S10815-020-01891-7  0.306
2020 Nielsen BS, Møller T, Kjems J. Automated One-Double-Z Pair BaseScope™ for CircRNA In Situ Hybridization. Methods in Molecular Biology (Clifton, N.J.). 2148: 379-388. PMID 32394395 DOI: 10.1007/978-1-0716-0623-0_24  0.387
2020 Das Mahapatra K, Pasquali L, Søndergaard JN, Lapins J, Nemeth IB, Baltás E, Kemény L, Homey B, Moldovan LI, Kjems J, Kutter C, Sonkoly E, Kristensen LS, Pivarcsi A. A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma. Scientific Reports. 10: 3637. PMID 32108138 DOI: 10.1038/S41598-020-59660-6  0.302
2019 Thomsen RP, Malle MG, Okholm AH, Krishnan S, Bohr SS, Sørensen RS, Ries O, Vogel S, Simmel FC, Hatzakis NS, Kjems J. A large size-selective DNA nanopore with sensing applications. Nature Communications. 10: 5655. PMID 31827087 DOI: 10.1038/S41467-019-13284-1  0.76
2019 Moldovan LI, Hansen TB, Venø MT, Okholm TLH, Andersen TL, Hager H, Iversen L, Kjems J, Johansen C, Kristensen LS. High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome. Bmc Medical Genomics. 12: 174. PMID 31775754 DOI: 10.1186/S12920-019-0616-2  0.309
2019 Klein WP, Thomsen RP, Turner KB, Walper SA, Vranish J, Kjems J, Ancona MG, Medintz IL. Enhanced Catalysis from Multienzyme Cascades Assembled on a DNA Origami Triangle. Acs Nano. PMID 31751123 DOI: 10.1021/Acsnano.9B05746  0.346
2019 Jepsen MDE, Sørensen RS, Maffeo C, Aksimentiev A, Kjems J, Birkedal V. Single molecule analysis of structural fluctuations in DNA nanostructures. Nanoscale. 11: 18475-18482. PMID 31577314 DOI: 10.1039/C9Nr03826D  0.762
2019 Kristensen LS, Andersen MS, Stagsted LVW, Ebbesen KK, Hansen TB, Kjems J. The biogenesis, biology and characterization of circular RNAs. Nature Reviews. Genetics. PMID 31395983 DOI: 10.1038/S41576-019-0158-7  0.351
2019 Verboom K, Everaert C, Bolduc N, Livak KJ, Yigit N, Rombaut D, Anckaert J, Lee S, Venø MT, Kjems J, Speleman F, Mestdagh P, Vandesompele J. SMARTer single cell total RNA sequencing. Nucleic Acids Research. PMID 31216024 DOI: 10.1093/Nar/Gkz535  0.351
2019 Raniolo S, Croce S, Thomsen RP, Okholm AH, Unida V, Iacovelli F, Manetto A, Kjems J, Desideri A, Biocca S. Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries. Nanoscale. PMID 31134260 DOI: 10.1039/C9Nr02006C  0.381
2019 Andersen VL, Vinther M, Kumar R, Ries A, Wengel J, Nielsen JS, Kjems J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics. 9: 2662-2677. PMID 31131060 DOI: 10.7150/Thno.32060  0.313
2019 Nielsen TB, Thomsen RP, Mortensen MR, Kjems J, Nielsen PF, Nielsen TE, Kodal ALB, Clo E, Gothelf KV. Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM. Angewandte Chemie (International Ed. in English). PMID 30995340 DOI: 10.1002/Anie.201903134  0.375
2019 Krissanaprasit A, Key C, Fergione M, Froehlich K, Pontula S, Hart M, Carriel P, Kjems J, Andersen ES, LaBean TH. Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant. Advanced Materials (Deerfield Beach, Fla.). e1808262. PMID 30972819 DOI: 10.1002/Adma.201808262  0.415
2019 Yan Y, Chang CC, Venø MT, Mothershead CR, Su J, Kjems J. Isolating, Sequencing and Analyzing Extracellular MicroRNAs from Human Mesenchymal Stem Cells. Journal of Visualized Experiments : Jove. PMID 30907893 DOI: 10.3791/58655  0.327
2018 Gothelf KV, Liu T, Song P, Märcher A, Kjems J, Yang C. Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab-DNA conjugates. Chembiochem : a European Journal of Chemical Biology. PMID 30589193 DOI: 10.1002/Cbic.201800685  0.324
2018 Hollensen AK, Andersen S, Hjorth K, Bak RO, Hansen TB, Kjems J, Aagaard L, Damgaard CK, Mikkelsen JG. Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs. Molecular Therapy. Nucleic Acids. 13: 365-375. PMID 30347350 DOI: 10.1016/J.Omtn.2018.09.009  0.305
2018 Mortensen MR, Skovsgaard M, Okholm AH, Scavenius C, Dupont DM, Rosen CB, Enghild JJ, Kjems J, Gothelf KV. Small-Molecule Probes for Affinity-Guided Introduction of Biocom-patible Handles on Metal-Binding Proteins. Bioconjugate Chemistry. PMID 30091905 DOI: 10.1021/Acs.Bioconjchem.8B00424  0.304
2018 Dahl M, Daugaard I, Andersen MS, Hansen TB, Grønbæk K, Kjems J, Kristensen LS. Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30087459 DOI: 10.1038/S41374-018-0108-6  0.336
2018 Højland Knudsen C, Ásgrímsdóttir ES, Rahimi K, Gill KP, Frandsen S, Hvolbøl Buchholdt S, Chen M, Kjems J, Febbraro F, Denham M. A Modified Monomeric Red Fluorescent Protein Reporter for Assessing CRISPR Activity. Frontiers in Cell and Developmental Biology. 6: 54. PMID 29868584 DOI: 10.3389/Fcell.2018.00054  0.3
2018 Høiberg HC, Sparvath SM, Andersen VL, Kjems J, Andersen ES. An RNA origami octahedron with intrinsic siRNAs for potent gene knockdown. Biotechnology Journal. e1700634. PMID 29802763 DOI: 10.1002/Biot.201700634  0.4
2018 Yang C, Gao S, Song P, Dagnaes-Hansen F, Jakobsen M, Kjems J. Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. Acs Applied Materials & Interfaces. PMID 29767944 DOI: 10.1021/Acsami.8B05513  0.333
2018 Stoll L, Sobel J, Rodriguez-Trejo A, Guay C, Lee K, Venø MT, Kjems J, Laybutt DR, Regazzi R. Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. Molecular Metabolism. PMID 29396373 DOI: 10.1016/J.Molmet.2018.01.010  0.324
2018 Kristensen LS, Dahl M, Andersen MS, Daugaard I, Hansen TB, Grønbæk K, Kjems J. Abstract LB-394: Profiling of endogenous circular RNA molecules in formalin-fixed paraffin-embedded tissues from patients with B-cell malignancies using an enzyme-free digital counting method Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-394  0.331
2017 Okholm TLH, Nielsen MM, Hamilton MP, Christensen LL, Vang S, Hedegaard J, Hansen TB, Kjems J, Dyrskjøt L, Pedersen JS. Circular RNA expression is abundant and correlated to aggressiveness in early-stage bladder cancer. Npj Genomic Medicine. 2: 36. PMID 29263845 DOI: 10.1038/S41525-017-0038-Z  0.306
2017 Grossi G, Dalgaard Ebbesen Jepsen M, Kjems J, Andersen ES. Control of enzyme reactions by a reconfigurable DNA nanovault. Nature Communications. 8: 992. PMID 29051565 DOI: 10.1038/S41467-017-01072-8  0.338
2017 Kristensen LS, Hansen TB, Venø MT, Kjems J. Circular RNAs in cancer: opportunities and challenges in the field. Oncogene. 37: 555-565. PMID 28991235 DOI: 10.1038/Onc.2017.361  0.319
2017 Manuguerra I, Grossi G, Thomsen RP, Lyngsø J, Pedersen JS, Kjems J, Andersen ES, Gothelf KV. Construction of a Polyhedral DNA 12-Arm Junction for Self-Assembly of Wireframe DNA Lattices. Acs Nano. PMID 28806061 DOI: 10.1021/Acsnano.7B03538  0.361
2017 Westergaard Mulberg M, Taskova M, Thomsen RP, Okholm AH, Kjems J, Astakhova K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem : a European Journal of Chemical Biology. PMID 28681411 DOI: 10.1002/Cbic.201700125  0.304
2017 Vogel S, Löffler PMG, Ries O, Rabe A, Okholm AH, Thomsen RP, Kjems J. A DNA-programmed liposome fusion cascade. Angewandte Chemie (International Ed. in English). PMID 28598002 DOI: 10.1002/Anie.201703243  0.338
2017 Domljanovic I, Carstens A, Okholm A, Kjems J, Nielsen CT, Heegaard NHH, Astakhova K. Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies. Scientific Reports. 7: 1925. PMID 28507286 DOI: 10.1038/S41598-017-02214-0  0.316
2017 Daugaard I, Venø MT, Yan Y, Kjeldsen TE, Lamy P, Hager H, Kjems J, Hansen LL. Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma. Oncotarget. 8: 27047-27061. PMID 28460486 DOI: 10.18632/Oncotarget.15968  0.304
2016 Ebbesen KK, Hansen TB, Kjems J. Insights into circular RNA biology. Rna Biology. 0. PMID 27982727 DOI: 10.1080/15476286.2016.1271524  0.351
2016 Okholm AH, Kjems J. The utility of DNA nanostructures for drug delivery in vivo. Expert Opinion On Drug Delivery. PMID 27892718 DOI: 10.1080/17425247.2017.1266335  0.319
2016 Qu S, Zhong Y, Shang R, Zhang X, Song W, Kjems J, Li H. The emerging landscape of circular RNA in life processes. Rna Biology. 1-8. PMID 27617908 DOI: 10.1080/15476286.2016.1220473  0.36
2016 Okholm AH, Kjems J. DNA nanovehicles and the biological barriers. Advanced Drug Delivery Reviews. PMID 27276176 DOI: 10.1016/J.Addr.2016.05.024  0.362
2016 Hansen TB, Venø MT, Jensen TI, Schaefer A, Damgaard CK, Kjems J. Argonaute-associated short introns are a novel class of gene regulators. Nature Communications. 7: 11538. PMID 27173734 DOI: 10.1038/Ncomms11538  0.305
2016 Schaffert DH, Okholm AH, Sørensen RS, Nielsen JS, Tørring T, Rosen CB, Kodal AL, Mortensen MR, Gothelf KV, Kjems J. Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway. Small (Weinheim An Der Bergstrasse, Germany). PMID 27032044 DOI: 10.1002/Smll.201503934  0.77
2015 Martirosyan A, Olesen MJ, Fenton RA, Kjems J, Howard KA. Mucin-mediated nanocarrier disassembly for triggered uptake of oligonucleotides as a delivery strategy for the potential treatment of mucosal tumours. Nanoscale. PMID 26694897 DOI: 10.1039/C5Nr07206A  0.316
2015 Venø MT, Hansen TB, Venø ST, Clausen BH, Grebing M, Finsen B, Holm IE, Kjems J. Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development. Genome Biology. 16: 245. PMID 26541409 DOI: 10.1186/S13059-015-0801-3  0.304
2015 Sükösd Z, Andersen ES, Seemann SE, Jensen MK, Hansen M, Gorodkin J, Kjems J. Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain. Nucleic Acids Research. PMID 26476446 DOI: 10.1093/Nar/Gkv1039  0.309
2015 Opazo F, Eiden L, Hansen L, Rohrbach F, Wengel J, Kjems J, Mayer G. Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. Molecular Therapy. Nucleic Acids. 4: e251. PMID 26325628 DOI: 10.1038/Mtna.2015.25  0.339
2015 Ebbesen KK, Kjems J, Hansen TB. Circular RNAs: Identification, biogenesis and function. Biochimica Et Biophysica Acta. PMID 26171810 DOI: 10.1016/J.Bbagrm.2015.07.007  0.348
2015 Dupont DM, Larsen N, Jensen JK, Andreasen PA, Kjems J. Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools. Nucleic Acids Research. PMID 26163061 DOI: 10.1093/Nar/Gkv700  0.344
2015 Okholm AH, Aslan H, Besenbacher F, Dong M, Kjems J. Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level. Nanoscale. 7: 10970-3. PMID 26061114 DOI: 10.1039/C5Nr01945A  0.357
2015 Jarczewska M, Kékedy-Nagy L, Nielsen JS, Campos R, Kjems J, Malinowska E, Ferapontova EE. Electroanalysis of pM-levels of urokinase plasminogen activator in serum by phosphorothioated RNA aptamer. The Analyst. 140: 3794-802. PMID 25620243 DOI: 10.1039/C4An02354D  0.3
2015 Zadegan RM, Jepsen MD, Hildebrandt LL, Birkedal V, Kjems J. Construction of a fuzzy and Boolean logic gates based on DNA. Small (Weinheim An Der Bergstrasse, Germany). 11: 1811-7. PMID 25565140 DOI: 10.1002/Smll.201402755  0.323
2015 Jepsen M, Sørensen RS, Andersen ES, Kjems J, Birkedal V. Single Molecule FRET Analysis of the Closed and Open States of a DNA Origami Box Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.968  0.768
2015 Jiang Z, Zhang S, Yang C, Kjems J, Huang Y, Besenbacher F, Dong M. Serum-induced degradation of 3D DNA box origami observed with high-speed atomic force microscopy Nano Research. DOI: 10.1007/S12274-015-0724-Z  0.329
2014 Cunyat F, Beerens N, García E, Clotet B, Kjems J, Cabrera C. Functional analyses reveal extensive RRE plasticity in primary HIV-1 sequences selected under selective pressure. Plos One. 9: e106299. PMID 25170621 DOI: 10.1371/Journal.Pone.0106299  0.341
2014 Rosen CB, Kodal AL, Nielsen JS, Schaffert DH, Scavenius C, Okholm AH, Voigt NV, Enghild JJ, Kjems J, Tørring T, Gothelf KV. Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins. Nature Chemistry. 6: 804-9. PMID 25143216 DOI: 10.1038/Nchem.2003  0.358
2014 Nielsen C, Kjems J, Sørensen KR, Engelholm LH, Behrendt N. Advances in targeted delivery of small interfering RNA using simple bioconjugates. Expert Opinion On Drug Delivery. 11: 791-822. PMID 24669756 DOI: 10.1517/17425247.2014.896898  0.338
2014 Okholm AH, Nielsen JS, Vinther M, Sørensen RS, Schaffert D, Kjems J. Quantification of cellular uptake of DNA nanostructures by qPCR. Methods (San Diego, Calif.). 67: 193-7. PMID 24472874 DOI: 10.1016/J.Ymeth.2014.01.013  0.768
2014 Nawroth I, Mueller F, Basyuk E, Beerens N, Rahbek UL, Darzacq X, Bertrand E, Kjems J, Schmidt U. Stable assembly of HIV-1 export complexes occurs cotranscriptionally. Rna (New York, N.Y.). 20: 1-8. PMID 24255166 DOI: 10.1261/Rna.038182.113  0.337
2013 Fang X, Wang J, O'Carroll IP, Mitchell M, Zuo X, Wang Y, Yu P, Liu Y, Rausch JW, Dyba MA, Kjems J, Schwieters CD, Seifert S, Winans RE, Watts NR, et al. An unusual topological structure of the HIV-1 Rev response element. Cell. 155: 594-605. PMID 24243017 DOI: 10.1016/J.Cell.2013.10.008  0.341
2013 Sørensen RS, Okholm AH, Schaffert D, Kodal AL, Gothelf KV, Kjems J. Enzymatic ligation of large biomolecules to DNA. Acs Nano. 7: 8098-104. PMID 23927463 DOI: 10.1021/Nn403386F  0.769
2013 Karlsen KK, Okholm A, Kjems J, Wengel J. A quencher-free molecular beacon design based on pyrene excimer fluorescence using pyrene-labeled UNA (unlocked nucleic acid). Bioorganic & Medicinal Chemistry. 21: 6186-90. PMID 23693070 DOI: 10.1016/J.Bmc.2013.04.062  0.326
2013 Iversen F, Yang C, Dagnæs-Hansen F, Schaffert DH, Kjems J, Gao S. Optimized siRNA-PEG conjugates for extended blood circulation and reduced urine excretion in mice. Theranostics. 3: 201-9. PMID 23471415 DOI: 10.7150/Thno.5743  0.308
2013 Ballarín-González B, Dagnaes-Hansen F, Fenton RA, Gao S, Hein S, Dong M, Kjems J, Howard KA. Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles. Molecular Therapy. Nucleic Acids. 2: e76. PMID 23462963 DOI: 10.1038/Mtna.2013.2  0.322
2013 Hansen TB, Jensen TI, Clausen BH, Bramsen JB, Finsen B, Damgaard CK, Kjems J. Natural RNA circles function as efficient microRNA sponges. Nature. 495: 384-8. PMID 23446346 DOI: 10.1038/Nature11993  0.307
2013 Beerens N, Jepsen MD, Nechyporuk-Zloy V, Krüger AC, Darlix JL, Kjems J, Birkedal V. Role of the primer activation signal in tRNA annealing onto the HIV-1 genome studied by single-molecule FRET microscopy. Rna (New York, N.Y.). 19: 517-26. PMID 23404895 DOI: 10.1261/Rna.035733.112  0.333
2013 Sükösd Z, Knudsen B, Anderson JW, Novák A, Kjems J, Pedersen CN. Characterising RNA secondary structure space using information entropy. Bmc Bioinformatics. 14: S22. PMID 23368905 DOI: 10.1186/1471-2105-14-S2-S22  0.317
2013 Bramsen JB, Kjems J. Engineering small interfering RNAs by strategic chemical modification. Methods in Molecular Biology (Clifton, N.J.). 942: 87-109. PMID 23027047 DOI: 10.1007/978-1-62703-119-6_5  0.339
2012 Kjems J, Howard KA. Oligonucleotide delivery to the lung: waiting to inhale. Molecular Therapy. Nucleic Acids. 1: e1. PMID 23344618 DOI: 10.1038/Mtna.2011.1  0.327
2012 Bramsen JB, Kjems J. Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering. Frontiers in Genetics. 3: 154. PMID 22934103 DOI: 10.3389/Fgene.2012.00154  0.343
2012 Jensen SM, Schmitz A, Pedersen FS, Kjems J, Bramsen JB. Functional selection of shRNA loops from randomized retroviral libraries. Plos One. 7: e43095. PMID 22912797 DOI: 10.1371/Journal.Pone.0043095  0.339
2012 Daniel C, Venø MT, Ekdahl Y, Kjems J, Öhman M. A distant cis acting intronic element induces site-selective RNA editing. Nucleic Acids Research. 40: 9876-86. PMID 22848101 DOI: 10.1093/Nar/Gks691  0.341
2012 Schyth BD, Bramsen JB, Pakula MM, Larashati S, Kjems J, Wengel J, Lorenzen N. In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important. Nucleic Acids Research. 40: 4653-65. PMID 22287630 DOI: 10.1093/Nar/Gks033  0.333
2012 Jepsen M, Beerens N, Krüger AC, Kjems J, Birkedal V. tRNA Annealing onto the HIV-1 Genome Studied by FRET Spectroscopy and Microscopy Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.1533  0.373
2011 Hansen TB, Wiklund ED, Bramsen JB, Villadsen SB, Statham AL, Clark SJ, Kjems J. miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. The Embo Journal. 30: 4414-22. PMID 21964070 DOI: 10.1038/Emboj.2011.359  0.323
2011 Birkedal V, Dong M, Golas MM, Sander B, Andersen ES, Gothelf KV, Besenbacher F, Kjems J. Single molecule microscopy methods for the study of DNA origami structures. Microscopy Research and Technique. 74: 688-98. PMID 21698717 DOI: 10.1002/Jemt.20962  0.355
2011 Sükösd Z, Knudsen B, Vaerum M, Kjems J, Andersen ES. Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars. Bmc Bioinformatics. 12: 103. PMID 21501497 DOI: 10.1186/1471-2105-12-103  0.306
2011 Bramsen JB, Kjems J. Chemical modification of small interfering RNA. Methods in Molecular Biology (Clifton, N.J.). 721: 77-103. PMID 21431680 DOI: 10.1007/978-1-61779-037-9_5  0.332
2011 Zhang Z, Olsen EM, Kryger M, Voigt NV, Tørring T, Gültekin E, Nielsen M, MohammadZadegan R, Andersen ES, Nielsen MM, Kjems J, Birkedal V, Gothelf KV. A DNA tile actuator with eleven discrete states. Angewandte Chemie (International Ed. in English). 50: 3983-7. PMID 21425422 DOI: 10.1002/Anie.201007642  0.302
2011 Jahn K, Tørring T, Voigt NV, Sørensen RS, Bank Kodal AL, Andersen ES, Gothelf KV, Kjems J. Functional patterning of DNA origami by parallel enzymatic modification. Bioconjugate Chemistry. 22: 819-23. PMID 21413714 DOI: 10.1021/Bc2000098  0.766
2011 Jahn K, Olsen EM, Nielsen MM, Tørring T, MohammadZadegan R, Andersen ES, Gothelf KV, Kjems J. Site-specific chemical labeling of long RNA molecules. Bioconjugate Chemistry. 22: 95-100. PMID 21138255 DOI: 10.1021/Bc100422K  0.372
2011 Lützelberger M, Kjems J. S1 nuclease analysis of alternatively spliced mRNA. Methods in Molecular Biology (Clifton, N.J.). 703: 161-71. PMID 21125489 DOI: 10.1007/978-1-59745-248-9_11  0.353
2010 Helmig S, Rotaru A, Arian D, Kovbasyuk L, Arnbjerg J, Ogilby PR, Kjems J, Mokhir A, Besenbacher F, Gothelf KV. Single molecule atomic force microscopy studies of photosensitized singlet oxygen behavior on a DNA origami template. Acs Nano. 4: 7475-80. PMID 21090671 DOI: 10.1021/Nn102701F  0.38
2010 Xu W, Wang JG, Jacobsen MF, Mura M, Yu M, Kelly RE, Meng QQ, Laegsgaard E, Stensgaard I, Linderoth TR, Kjems J, Kantorovich LN, Gothelf KV, Besenbacher F. Supramolecular porous network formed by molecular recognition between chemically modified nucleobases guanine and cytosine. Angewandte Chemie (International Ed. in English). 49: 9373-7. PMID 21064057 DOI: 10.1002/Anie.201003390  0.348
2010 Dupont DM, Madsen JB, Hartmann RK, Tavitian B, Ducongé F, Kjems J, Andreasen PA. Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding. Rna (New York, N.Y.). 16: 2360-9. PMID 20962041 DOI: 10.1261/Rna.2338210  0.35
2010 Laursen MB, Pakula MM, Gao S, Fluiter K, Mook OR, Baas F, Langklaer N, Wengel SL, Wengel J, Kjems J, Bramsen JB. Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo. Molecular Biosystems. 6: 862-70. PMID 20567772 DOI: 10.1039/B918869J  0.389
2010 Bramsen JB, Pakula MM, Hansen TB, Bus C, Langkjær N, Odadzic D, Smicius R, Wengel SL, Chattopadhyaya J, Engels JW, Herdewijn P, Wengel J, Kjems J. A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects. Nucleic Acids Research. 38: 5761-73. PMID 20453030 DOI: 10.1093/Nar/Gkq341  0.328
2010 Beerens N, Kjems J. Circularization of the HIV-1 genome facilitates strand transfer during reverse transcription. Rna (New York, N.Y.). 16: 1226-35. PMID 20430859 DOI: 10.1261/Rna.2039610  0.315
2010 Madsen JB, Dupont DM, Andersen TB, Nielsen AF, Sang L, Brix DM, Jensen JK, Broos T, Hendrickx ML, Christensen A, Kjems J, Andreasen PA. RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1. Biochemistry. 49: 4103-15. PMID 20387790 DOI: 10.1021/Bi100066J  0.31
2010 Krüger AC, Raarup MK, Nielsen MM, Kristensen M, Besenbacher F, Kjems J, Birkedal V. Interaction of hnRNP A1 with telomere DNA G-quadruplex structures studied at the single molecule level. European Biophysics Journal : Ebj. 39: 1343-50. PMID 20213319 DOI: 10.1007/S00249-010-0587-X  0.333
2010 Voigt NV, Tørring T, Rotaru A, Jacobsen MF, Ravnsbaek JB, Subramani R, Mamdouh W, Kjems J, Mokhir A, Besenbacher F, Gothelf KV. Single-molecule chemical reactions on DNA origami. Nature Nanotechnology. 5: 200-3. PMID 20190747 DOI: 10.1038/Nnano.2010.5  0.375
2009 Pallesen J, Dong M, Besenbacher F, Kjems J. Structure of the HIV-1 Rev response element alone and in complex with regulator of virion (Rev) studied by atomic force microscopy. The Febs Journal. 276: 4223-32. PMID 19583776 DOI: 10.1111/J.1742-4658.2009.07130.X  0.331
2009 Molle D, Segura-Morales C, Camus G, Berlioz-Torrent C, Kjems J, Basyuk E, Bertrand E. Endosomal Trafficking of HIV-1 Gag and Genomic RNAs Regulates Viral Egress Journal of Biological Chemistry. 284: 19727-19743. PMID 19451649 DOI: 10.1074/Jbc.M109.019844  0.303
2009 Glud SZ, Bramsen JB, Dagnaes-Hansen F, Wengel J, Howard KA, Nyengaard JR, Kjems J. Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. Oligonucleotides. 19: 163-8. PMID 19441893 DOI: 10.1089/Oli.2008.0175  0.301
2009 Andersen ES, Dong M, Nielsen MM, Jahn K, Subramani R, Mamdouh W, Golas MM, Sander B, Stark H, Oliveira CL, Pedersen JS, Birkedal V, Besenbacher F, Gothelf KV, Kjems J. Self-assembly of a nanoscale DNA box with a controllable lid. Nature. 459: 73-6. PMID 19424153 DOI: 10.1038/Nature07971  0.371
2009 Gao S, Dagnaes-Hansen F, Nielsen EJ, Wengel J, Besenbacher F, Howard KA, Kjems J. The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1225-33. PMID 19401674 DOI: 10.1038/Mt.2009.91  0.335
2009 Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjoør N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, ... ... Kjems J, et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity Nucleic Acids Research. 37: 2867-2881. PMID 19282453 DOI: 10.1093/Nar/Gkp106  0.344
2008 Andersen ES, Dong M, Nielsen MM, Jahn K, Lind-Thomsen A, Mamdouh W, Gothelf KV, Besenbacher F, Kjems J. DNA origami design of dolphin-shaped structures with flexible tails. Acs Nano. 2: 1213-8. PMID 19206339 DOI: 10.1021/Nn800215J  0.362
2008 Otero R, Xu W, Lukas M, Kelly RE, Laegsgaard E, Stensgaard I, Kjems J, Kantorovich LN, Besenbacher F. Specificity of watson-crick base pairing on a solid surface studied at the atomic scale. Angewandte Chemie (International Ed. in English). 47: 9673-6. PMID 19003837 DOI: 10.1002/Anie.200803333  0.342
2008 Astakhova IV, Korshun VA, Jahn K, Kjems J, Wengel J. Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture. Bioconjugate Chemistry. 19: 1995-2007. PMID 18771303 DOI: 10.1021/Bc800202V  0.344
2008 Torarinsson E, Yao Z, Wiklund ED, Bramsen JB, Hansen C, Kjems J, Tommerup N, Ruzzo WL, Gorodkin J. Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions. Genome Research. 18: 242-51. PMID 18096747 DOI: 10.1101/Gr.6887408  0.341
2008 Rahbek UL, Howard KA, Oupicky D, Manickam DS, Dong M, Nielsen AF, Hansen TB, Besenbacher F, Kjems J. Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides. The Journal of Gene Medicine. 10: 81-93. PMID 18000993 DOI: 10.1002/Jgm.1120  0.331
2008 Andersen MØ, Howard KA, Paludan SR, Besenbacher F, Kjems J. Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials. 29: 506-12. PMID 17950838 DOI: 10.1016/J.Biomaterials.2007.10.003  0.315
2008 Odadzic D, Bramsen JB, Smicius R, Bus C, Kjems J, Engels JW. Synthesis of 2'-O-modified adenosine building blocks and application for RNA interference. Bioorganic & Medicinal Chemistry. 16: 518-529. PMID 17904849 DOI: 10.1016/J.Bmc.2007.09.019  0.343
2007 Howard KA, Kjems J. Polycation-based nanoparticle delivery for improved RNA interference therapeutics. Expert Opinion On Biological Therapy. 7: 1811-22. PMID 18034647 DOI: 10.1517/14712598.7.12.1811  0.352
2007 Andersen ES, Lind-Thomsen A, Knudsen B, Kristensen SE, Havgaard JH, Torarinsson E, Larsen N, Zwieb C, Sestoft P, Kjems J, Gorodkin J. Semiautomated improvement of RNA alignments. Rna (New York, N.Y.). 13: 1850-9. PMID 17804647 DOI: 10.1261/Rna.215407  0.34
2007 Bramsen JB, Laursen MB, Damgaard CK, Lena SW, Babu BR, Wengel J, Kjems J. Improved silencing properties using small internally segmented interfering RNAs Nucleic Acids Research. 35: 5886-5897. PMID 17726057 DOI: 10.1093/Nar/Gkm548  0.367
2007 Lykke-Andersen S, Piñol-Roma S, Kjems J. Alternative splicing of the ADAR1 transcript in a region that functions either as a 5'-UTR or an ORF. Rna (New York, N.Y.). 13: 1732-44. PMID 17698644 DOI: 10.1261/Rna.567807  0.302
2006 Howard KA, Rahbek UL, Liu X, Damgaard CK, Glud SZ, Andersen MØ, Hovgaard MB, Schmitz A, Nyengaard JR, Besenbacher F, Kjems J. RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 476-84. PMID 16829204 DOI: 10.1016/J.Ymthe.2006.04.010  0.342
2006 Lützelberger M, Reinert LS, Das AT, Berkhout B, Kjems J. A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability Journal of Biological Chemistry. 281: 18644-18651. PMID 16675444 DOI: 10.1074/Jbc.M513698200  0.336
2006 Lützelberger M, Kjems J. Strategies to identify potential therapeutic target sites in RNA. Handbook of Experimental Pharmacology. 173: 243-259. PMID 16594619 DOI: 10.1007/3-540-27262-3_12  0.396
2005 Mukhopadhyay R, Lorentzen M, Kjems J, Besenbacher F. Nanomechanical sensing of DNA sequences using piezoresistive cantilevers. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 8400-8. PMID 16114949 DOI: 10.1021/La0511687  0.376
2005 Nielsen M, Dauksaite V, Kjems J, Gothelf KV. DNA-directed coupling of organic modules by multiple parallel reductive aminations and subsequent cleavage of selected DNA sequences Bioconjugate Chemistry. 16: 981-985. PMID 16029040 DOI: 10.1021/Bc0500793  0.347
2005 Furnes C, Arnesen T, Askjaer P, Kjems J, Szilvay AM. HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain. Retrovirology. 2: 39. PMID 15949040 DOI: 10.1186/1742-4690-2-39  0.331
2004 Knudsen B, Andersen ES, Damgaard C, Kjems J, Gorodkin J. Evolutionary rate variation and RNA secondary structure prediction. Computational Biology and Chemistry. 28: 219-26. PMID 15261152 DOI: 10.1016/J.Compbiolchem.2004.04.001  0.312
2004 Jakobsen MR, Damgaard CK, Andersen ES, Podhajska A, Kjems J. A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA. Nucleic Acids Research. 32: e67. PMID 15107482 DOI: 10.1093/Nar/Gnh064  0.372
2004 Andersen ES, Contera SA, Knudsen B, Damgaard CK, Besenbacher F, Kjems J. Role of the trans-activation response element in dimerization of HIV-1 RNA. The Journal of Biological Chemistry. 279: 22243-9. PMID 15014074 DOI: 10.1074/Jbc.M314326200  0.349
2004 Damgaard CK, Andersen ES, Knudsen B, Gorodkin J, Kjems J. RNA interactions in the 5' region of the HIV-1 genome. Journal of Molecular Biology. 336: 369-79. PMID 14757051 DOI: 10.1016/J.Jmb.2003.12.010  0.33
2003 Freund M, Asang C, Kammler S, Konermann C, Krummheuer J, Hipp M, Meyer I, Gierling W, Theiss S, Preuss T, Schindler D, Kjems J, Schaal H. A novel approach to describe a U1 snRNA binding site. Nucleic Acids Research. 31: 6963-75. PMID 14627829 DOI: 10.1093/Nar/Gkg901  0.3
2003 Andersen ES, Jeeninga RE, Damgaard CK, Berkhout B, Kjems J. Dimerization and template switching in the 5' untranslated region between various subtypes of human immunodeficiency virus type 1. Journal of Virology. 77: 3020-30. PMID 12584327 DOI: 10.1128/Jvi.77.5.3020-3030.2003  0.354
2002 Damgaard CK, Tange TØ, Kjems J. hnRNP A1 controls HIV-1 mRNA splicing through cooperative binding to intron and exon splicing silencers in the context of a conserved secondary structure. Rna. 8: 1401-1415. PMID 12458794 DOI: 10.1017/S1355838202023075  0.304
2002 Andersen FF, Tange TØ, Sinnathamby T, Olesen JR, Andersen KE, Westergaard O, Kjems J, Knudsen BR. The RNA splicing factor ASF/SF2 inhibits human topoisomerase I mediated DNA relaxation Journal of Molecular Biology. 322: 677-686. PMID 12270705 DOI: 10.1016/S0022-2836(02)00815-X  0.363
2002 Dirac AM, Huthoff H, Kjems J, Berkhout B. Regulated HIV-2 RNA dimerization by means of alternative RNA conformations. Nucleic Acids Research. 30: 2647-55. PMID 12060681 DOI: 10.1093/Nar/Gkf381  0.322
2002 Lindtner S, Felber BK, Kjems J. An element in the 3' untranslated region of human LINE-1 retrotransposon mRNA binds NXF1(TAP) and can function as a nuclear export element. Rna. 8: 345-356. PMID 12003494 DOI: 10.1017/S1355838202027759  0.348
2001 Poulsen H, Nilsson J, Damgaard CK, Egebjerg J, Kjems J. CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain. Molecular and Cellular Biology. 21: 7862-7871. PMID 11604520 DOI: 10.1128/Mcb.21.22.7862-7871.2001  0.38
2001 Tange TØ, Kjems J. SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain. Journal of Molecular Biology. 312: 649-62. PMID 11575921 DOI: 10.1006/Jmbi.2001.4971  0.302
2001 Dirac AMG, Kjems J. Mapping DNA-binding sites of HIV-1 integrase by protein footprinting. Febs Journal. 268: 743-751. PMID 11168414 DOI: 10.1046/J.1432-1327.2001.01932.X  0.338
2000 Askjaer P, Rosendahl R, Kjems J. Nuclear Export of the DEAD Box An3 Protein by CRM1 Is Coupled to An3 Helicase Activity Journal of Biological Chemistry. 275: 11561-11568. PMID 10766770 DOI: 10.1074/Jbc.275.16.11561  0.352
1999 Askjaer P, Bachi A, Wilm M, Bischoff FR, Weeks DL, Ogniewski V, Ohno M, Niehrs C, Kjems J, Mattaj IW, Fornerod M. RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Molecular and Cellular Biology. 19: 6276-85. PMID 10454574 DOI: 10.1128/Mcb.19.9.6276  0.309
1998 Askjaer P, Jensen TH, Nilsson J, Englmeier L, Kjems J. The Specificity of the CRM1-Rev Nuclear Export Signal Interaction Is Mediated by RanGTP* Journal of Biological Chemistry. 273: 33414-33422. PMID 9837918 DOI: 10.1074/Jbc.273.50.33414  0.323
1998 Jensen A, Jensen TH, Kjems J. HIV-1 rev nuclear export signal binding peptides isolated by phage display. Journal of Molecular Biology. 283: 245-54. PMID 9761687 DOI: 10.1006/Jmbi.1998.2085  0.324
1998 Damgaard CK, Dyhr-Mikkelsen H, Kjems J. Mapping the RNA binding sites for human immunodeficiency virus type-1 gag and NC proteins within the complete HIV-1 and -2 untranslated leader regions. Nucleic Acids Research. 26: 3667-76. PMID 9685481 DOI: 10.1093/Nar/26.16.3667  0.319
1998 Askjaer P, Kjems J. Mapping of multiple RNA binding sites of human T-cell lymphotropic virus type I rex protein within 5'- and 3'-Rex response elements. Journal of Biological Chemistry. 273: 11463-11471. PMID 9565558 DOI: 10.1074/Jbc.273.19.11463  0.333
1998 Kjems J, Egebjerg J. Modern methods for probing RNA structure. Current Opinion in Biotechnology. 9: 59-65. PMID 9503589 DOI: 10.1016/S0958-1669(98)80085-2  0.337
1996 Lykke-Andersen J, Garrett RA, Kjems J. Protein Footprinting Approach to Mapping DNA Binding Sites of Two Archaeal Homing Enzymes: Evidence for a Two-Domain Protein Structure Nucleic Acids Research. 24: 3982-3989. PMID 8918801 DOI: 10.1093/Nar/24.20.3982  0.343
1995 Jensen TH, Leffers H, Kjems J. Intermolecular Binding Sites of Human Immunodeficiency Virus Type 1 Rev Protein Determined by Protein Footprinting Journal of Biological Chemistry. 270: 13777-13784. PMID 7539792 DOI: 10.1074/Jbc.270.23.13777  0.312
1993 Kjems J, Sharp PA. The basic domain of Rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6.U5 small nuclear ribonucleoprotein in spliceosome assembly. Journal of Virology. 67: 4769-76. PMID 8331728 DOI: 10.1128/Jvi.67.8.4769-4776.1993  0.505
1992 Kjems J, Calnan BJ, Frankel AD, Sharp PA. Specific binding of a basic peptide from HIV-1 Rev. The Embo Journal. 11: 1119-29. PMID 1547776 DOI: 10.1002/J.1460-2075.1992.Tb05152.X  0.516
1991 Kjems J, Brown M, Chang DD, Sharp PA. Structural analysis of the interaction between the human immunodeficiency virus Rev protein and the Rev response element. Proceedings of the National Academy of Sciences of the United States of America. 88: 683-7. PMID 1992459 DOI: 10.1073/Pnas.88.3.683  0.603
1991 Kjems J, Frankel AD, Sharp PA. Specific regulation of mRNA splicing in vitro by a peptide from HIV-1 Rev. Cell. 67: 169-78. PMID 1913815 DOI: 10.1016/0092-8674(91)90580-R  0.494
1991 Kjems J, Garrett RA. Ribosomal RNA introns in archaea and evidence for RNA conformational changes associated with splicing. Proceedings of the National Academy of Sciences of the United States of America. 88: 439-43. PMID 1899138 DOI: 10.1073/Pnas.88.2.439  0.353
1990 Kjems J, Garrett RA. Secondary structural elements exclusive to the sequences flanking ribosomal RNAs lend support to the monophyletic nature of the archaebacteria. Journal of Molecular Evolution. 31: 25-32. PMID 1696321 DOI: 10.1007/Bf02101789  0.353
1990 Kjems J, Leffers H, Olesen T, Holz I, Garrett RA. Sequence, Organization and Transcription of the Ribosomal RNA Operon and the Downstream tRNA and Protein Genes in the Archaebacterium Thermofilum pendents Systematic and Applied Microbiology. 13: 117-127. DOI: 10.1016/S0723-2020(11)80157-8  0.358
1989 Kjems J, Jensen J, Olesen T, Garrett RA. Comparison of transfer RNA and ribosomal RNA intron splicing in the extreme thermophile and archaebacterium Desulfurococcus mobilis. Canadian Journal of Microbiology. 35: 210-4. PMID 2470485 DOI: 10.1139/M89-033  0.332
1988 Kjems J, Garrett RA. Novel splicing mechanism for the ribosomal RNA intron in the archaebacterium Desulfurococcus mobilis. Cell. 54: 693-703. PMID 3136929 DOI: 10.1016/S0092-8674(88)80014-X  0.352
1987 Leffers H, Kjems J, Ostergaard L, Larsen N, Garrett RA. Evolutionary relationships amongst archaebacteria. A comparative study of 23 S ribosomal RNAs of a sulphur-dependent extreme thermophile, an extreme halophile and a thermophilic methanogen. Journal of Molecular Biology. 195: 43-61. PMID 3116261 DOI: 10.1016/0022-2836(87)90326-3  0.347
1987 Kjems J, Leffers H, Garrett RA, Wich G, Leinfelder W, Böck A. Gene organization, transcription signals and processing of the single ribosomal RNA operon of the archaebacterium Thermoproteus tenax. Nucleic Acids Research. 15: 4821-35. PMID 2439991 DOI: 10.1093/Nar/15.12.4821  0.338
1987 Kjems J, Garrett RA, Ansorge W. The sequence of the 16S RNA gene and its flanking region from the archaebacterium Desulfurococcus mobilis Systematic and Applied Microbiology. 9: 22-28. DOI: 10.1016/S0723-2020(87)80051-6  0.344
1987 Østergaard L, Larsen N, Leffers H, Kjems J, Garrett R. A Ribosomal RNA Operon and its Flanking Region from the Archaebacterium Methanobacterium thermoautotrophicum, Marburg Strain: Transcription Signals, RNA Structure and Evolutionary Implications Systematic and Applied Microbiology. 9: 199-209. DOI: 10.1016/S0723-2020(87)80022-X  0.341
1987 Kjems J, Garrett RA. Novel expression of the ribosomal RNA genes in the extreme thermophile and archaebacterium Desulfurococcus mobilis The Embo Journal. 6: 3521-3530. DOI: 10.1002/J.1460-2075.1987.Tb02678.X  0.339
1986 Larsen N, Leffers H, Kjems J, Garrett RA. Evolutionary divergence between the ribosomal RNA operons of Halococcus morrhuae and Desulfurococcus mobilis Systematic and Applied Microbiology. 7: 49-57. DOI: 10.1016/S0723-2020(86)80123-0  0.344
1985 Kjems J, Garrett RA. An intron in the 23S ribosomal RNA gene of the archaebacterium Desulfurococcus mobilis Nature. 318: 675-677. PMID 23991468 DOI: 10.1038/318675A0  0.339
1985 Kjems J, Olesen SO, Garrett RA. Comparison of eubacterial and eukaryotic 5S RNA structures: a chemical modification study. Biochemistry. 24: 241-250. PMID 3884039 DOI: 10.1021/Bi00323A002  0.348
Show low-probability matches.