Denis Vivien - Publications

Affiliations: 
INSERM U919, Cyceron, Caen, Caen, Normandie, France 
Area:
stroke, plasminogen activator, tgf-beta

207 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Prunotto P, Marie P, Lebouvier L, Hommet Y, Vivien D, Ali C. The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons. Cell Death & Disease. 15: 261. PMID 38609369 DOI: 10.1038/s41419-024-06655-0  0.31
2024 Villa-González M, Rubio M, Martín-López G, Mallavibarrena PR, Vallés-Saiz L, Vivien D, Wandosell F, Pérez-Álvarez MJ. Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity. Biology Direct. 19: 26. PMID 38582839 DOI: 10.1186/s13062-024-00470-5  0.348
2024 Furon J, Lebrun F, Yétim M, Levard D, Marie P, Orset C, Martinez de Lizarrondo S, Vivien D, Ali C. Parabiosis Discriminates the Circulating, Endothelial, and Parenchymal Contributions of Endogenous Tissue-Type Plasminogen Activator to Stroke. Stroke. PMID 38288607 DOI: 10.1161/STROKEAHA.123.045048  0.353
2023 Furon J, Yetim M, Pouettre E, Martinez de Lizarrondo S, Maubert E, Hommet Y, Lebouvier L, Zheng Z, Ali C, Vivien D. Blood tissue Plasminogen Activator (tPA) of liver origin contributes to neurovascular coupling involving brain endothelial N-Methyl-D-Aspartate (NMDA) receptors. Fluids and Barriers of the Cns. 20: 11. PMID 36737775 DOI: 10.1186/s12987-023-00411-w  0.305
2022 Zuba V, Furon J, Bellemain-Sagnard M, de Lazarrondo SM, Lebouvier L, Rubio M, Hommet Y, Gauberti M, Vivien D, Ali C. Correction to: The choroid plexus: A door between the blood and the brain for tissue-type plasminogen activator. Fluids and Barriers of the Cns. 19: 83. PMID 36320083 DOI: 10.1186/s12987-022-00383-3  0.648
2022 Zuba V, Furon J, Bellemain-Sagnard M, Martinez de Lizarrondo S, Lebouvier L, Rubio M, Hommet Y, Gauberti M, Vivien D, Ali C. The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator. Fluids and Barriers of the Cns. 19: 80. PMID 36243724 DOI: 10.1186/s12987-022-00378-0  0.67
2022 Lépine M, Douceau S, Devienne G, Prunotto P, Lenoir S, Regnauld C, Pouettre E, Piquet J, Lebouvier L, Hommet Y, Maubert E, Agin V, Lambolez B, Cauli B, Ali C, ... Vivien D, et al. Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure. Bmc Biology. 20: 218. PMID 36199089 DOI: 10.1186/s12915-022-01419-8  0.65
2022 Seillier C, Lesept F, Toutirais O, Potzeha F, Blanc M, Vivien D. Targeting NMDA Receptors at the Neurovascular Unit: Past and Future Treatments for Central Nervous System Diseases. International Journal of Molecular Sciences. 23. PMID 36142247 DOI: 10.3390/ijms231810336  0.301
2022 Drieu A, Lanquetin A, Prunotto P, Gulhan Z, Pédron S, Vegliante G, Tolomeo D, Serrière S, Vercouillie J, Galineau L, Tauber C, Kuhnast B, Rubio M, Zanier ER, Levard D, ... ... Vivien D, et al. Persistent neuroinflammation and behavioural deficits after single mild traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221119288. PMID 35945692 DOI: 10.1177/0271678X221119288  0.632
2022 Tomadesso C, de Lizarrondo SM, Ali C, Landeau B, Mézenge F, Perrotin A, de La Sayette V, Vivien D, Chételat G. Plasma Levels of Tissue-Type Plasminogen Activator (tPA) in Normal Aging and Alzheimer's Disease: Links With Cognition, Brain Structure, Brain Function and Amyloid Burden. Frontiers in Aging Neuroscience. 14: 871214. PMID 35747448 DOI: 10.3389/fnagi.2022.871214  0.623
2022 Metayer T, Orset C, Ali C, Furon J, Szabla N, Emery E, Vivien D, Gaberel T. Bumetanide lowers acute hydrocephalus in a rat model of subarachnoid hemorrhage. Acta Neurochirurgica. PMID 35094147 DOI: 10.1007/s00701-021-05088-4  0.618
2021 Hedou E, Douceau S, Chevilley A, Varangot A, Thiebaut AM, Triniac H, Bardou I, Ali C, Maillasson M, Crepaldi T, Comoglio P, Lemarchand E, Agin V, Roussel BD, Vivien D. Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival. International Journal of Molecular Sciences. 22. PMID 34948279 DOI: 10.3390/ijms222413483  0.682
2021 Goursaud S, Martinez de Lizarrondo S, Grolleau F, Chagnot A, Agin V, Maubert E, Gauberti M, Vivien D, Ali C, Gakuba C. Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: Is There a Relevant Experimental Model? A Systematic Review of Preclinical Literature. Frontiers in Cardiovascular Medicine. 8: 752769. PMID 34869659 DOI: 10.3389/fcvm.2021.752769  0.634
2021 Garnier E, Levard D, Ali C, Buendia I, Hommet Y, Gauberti M, Crepaldi T, Comoglio P, Rubio M, Vivien D, Docagne F, Martinez de Lizarrondo S. Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor-dependent mechanisms. Journal of Thrombosis and Haemostasis : Jth. PMID 34060720 DOI: 10.1111/jth.15414  0.671
2021 Salaün JP, Poirel N, Dahmani S, Chagnot A, Gakuba C, Ali C, Gérard JL, Hanouz JL, Orliaguet G, Vivien D. Preventing the long-term effects of general anesthesia on the developing brain: how translational research can contribute. Neuroscience. PMID 33675916 DOI: 10.1016/j.neuroscience.2021.02.029  0.603
2021 Boltze J, Aronowski JA, Badaut J, Buckwalter MS, Caleo M, Chopp M, Dave KR, Didwischus N, Dijkhuizen RM, Doeppner TR, Dreier JP, Fouad K, Gelderblom M, Gertz K, Golubczyk D, ... ... Vivien D, et al. New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases. Frontiers in Aging Neuroscience. 13: 623751. PMID 33584250 DOI: 10.3389/fnagi.2021.623751  0.713
2021 Anfray A, Brodin C, Drieu A, Potzeha F, Dalarun B, Agin V, Vivien D, Orset C. Single- and two- chain tissue type plasminogen activator treatments differentially influence cerebral recovery after stroke. Experimental Neurology. 338: 113606. PMID 33453214 DOI: 10.1016/j.expneurol.2021.113606  0.319
2020 Wagnon I, Hélie P, Bardou I, Regnauld C, Lesec L, Leprince J, Naveau M, Delaunay B, Toutirais O, Lemauff B, Etard O, Vivien D, Agin V, Macrez R, Maubert E, et al. Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor. Brain : a Journal of Neurology. PMID 32893288 DOI: 10.1093/Brain/Awaa250  0.32
2020 Arkelius K, Vivien D, Orset C, Ansar S. Validation of a stroke model in rat compatible with rt-PA-induced thrombolysis: new hope for successful translation to the clinic. Scientific Reports. 10: 12191. PMID 32699371 DOI: 10.1038/s41598-020-69081-0  0.409
2020 Hingot V, Brodin C, Lebrun F, Heiles B, Chagnot A, Yetim M, Gauberti M, Orset C, Tanter M, Couture O, Deffieux T, Vivien D. Early Ultrafast Ultrasound Imaging of Cerebral Perfusion correlates with Ischemic Stroke outcomes and responses to treatment in Mice. Theranostics. 10: 7480-7491. PMID 32685000 DOI: 10.7150/thno.44233  0.4
2020 Debatisse J, Wateau O, Cho TH, Costes N, Mérida I, Léon C, Langlois JB, Taborik F, Verset M, Portier K, Aggour M, Troalen T, Villien M, Makris N, Tourvieille C, ... ... Vivien D, et al. A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20921310. PMID 32428423 DOI: 10.1177/0271678X20921310  0.413
2020 Soize S, Pierot L, Mirza M, Gunning G, Gilvarry M, Gawlitza M, Vivien D, Zuber M, Touzé E. Fast Stent Retrieval Improves Recanalization Rates of Thrombectomy: Experimental Study on Different Thrombi. Ajnr. American Journal of Neuroradiology. 41: 1049-1053. PMID 32409312 DOI: 10.3174/ajnr.A6559  0.32
2020 Drieu A, Lanquetin A, Levard D, Glavan M, Campos F, Quenault A, Lemarchand E, Naveau M, Pitel AL, Castillo J, Vivien D, Rubio M. Alcohol exposure-induced neurovascular inflammatory priming impacts ischemic stroke and is linked with brain perivascular macrophages. Jci Insight. PMID 31990687 DOI: 10.1172/Jci.Insight.129226  0.353
2020 Mehra A, Guérit S, Macrez R, Gosselet F, Sevin E, Lebas H, Maubert E, De Vries HE, Bardou I, Vivien D, Docagne F. Non-ionotropic action of endothelial NMDA receptors on blood-brain barrier permeability via Rho/ROCK mediated phosphorylation of myosin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31953371 DOI: 10.1523/JNEUROSCI.0969-19.2019  0.416
2019 Dupré N, Arabo A, Orset C, Maucotel J, Detroussel Y, Hauchecorne M, Gonzalez BJ, Marret S, Vivien D, Leroux P. Neonatal cerebral hypoxia-ischemia in mice triggers age-dependent vascular effects and disabilities in adults; implication of tissue plasminogen activator (tPA). Experimental Neurology. 113087. PMID 31697944 DOI: 10.1016/j.expneurol.2019.113087  0.346
2019 Anfray A, Drieu A, Hingot V, Hommet Y, Yetim M, Rubio M, Deffieux T, Tanter M, Orset C, Vivien D. Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19883599. PMID 31665952 DOI: 10.1177/0271678X19883599  0.399
2019 Drieu A, Buendia I, Levard D, Hélie P, Brodin C, Vivien D, Rubio M. Immune Responses and Anti-inflammatory Strategies in a Clinically Relevant Model of Thromboembolic Ischemic Stroke with Reperfusion. Translational Stroke Research. PMID 31522409 DOI: 10.1007/s12975-019-00733-8  0.372
2019 Léger C, Dupré N, Aligny C, Bénard M, Lebon A, Henry V, Hauchecorne M, Galas L, Frebourg T, Leroux P, Vivien D, Lecointre M, Marret S, Gonzalez BJ. Glutamate controls vessel-associated migration of GABA interneurons from the pial migratory route via NMDA receptors and endothelial protease activation. Cellular and Molecular Life Sciences : Cmls. PMID 31392351 DOI: 10.1007/s00018-019-03248-5  0.358
2019 Vegliante G, Tolomeo D, Drieu A, Rubio M, Micotti E, Moro F, Vivien D, Forloni G, Ali C, Zanier ER. Longitudinal Molecular Magnetic Resonance Imaging of Endothelial Activation after Severe Traumatic Brain Injury. Journal of Clinical Medicine. 8. PMID 31366109 DOI: 10.3390/jcm8081134  0.658
2019 Correa-Paz C, Navarro Poupard MF, Polo E, Rodríguez-Pérez M, Taboada P, Iglesias-Rey R, Hervella P, Sobrino T, Vivien D, Castillo J, Del Pino P, Campos F, Pelaz B. In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31310784 DOI: 10.1016/J.Jconrel.2019.07.017  0.344
2019 Thiebaut AM, Hedou E, Marciniak SJ, Vivien D, Roussel BD. Proteostasis During Cerebral Ischemia. Frontiers in Neuroscience. 13: 637. PMID 31275110 DOI: 10.3389/fnins.2019.00637  0.393
2019 Lenoir S, Varangot A, Lebouvier L, Galli T, Hommet Y, Vivien D. Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA). Frontiers in Cellular Neuroscience. 13: 164. PMID 31105531 DOI: 10.3389/fncel.2019.00164  0.333
2019 Bonnard T, Gauberti M, Martinez de Lizarrondo S, Campos F, Vivien D. Recent Advances in Nanomedicine for Ischemic and Hemorrhagic Stroke. Stroke. STROKEAHA118022744. PMID 30932782 DOI: 10.1161/STROKEAHA.118.022744  0.366
2018 Gauberti M, Lapergue B, Martinez de Lizarrondo S, Vivien D, Richard S, Bracard S, Piotin M, Gory B. Ischemia-Reperfusion Injury After Endovascular Thrombectomy for Ischemic Stroke. Stroke. 49: 3071-3074. PMID 30571423 DOI: 10.1161/STROKEAHA.118.022015  0.326
2018 Thiebaut AM, Gauberti M, Ali C, Martinez De Lizarrondo S, Vivien D, Yepes M, Roussel BD. The role of plasminogen activators in stroke treatment: fibrinolysis and beyond. The Lancet. Neurology. 17: 1121-1132. PMID 30507392 DOI: 10.1016/S1474-4422(18)30323-5  0.706
2018 Vezain M, Lecuyer M, Rubio M, Dupé V, Ratié L, David V, Pasquier L, Odent S, Coutant S, Tournier I, Trestard L, Adle-Biassette H, Vivien D, Frébourg T, Gonzalez BJ, et al. A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis. Acta Neuropathologica Communications. 6: 109. PMID 30340542 DOI: 10.1186/s40478-018-0610-5  0.309
2018 Drieu A, Levard D, Vivien D, Rubio M. Anti-inflammatory treatments for stroke: from bench to bedside. Therapeutic Advances in Neurological Disorders. 11: 1756286418789854. PMID 30083232 DOI: 10.1177/1756286418789854  0.398
2018 Gauberti M, Potzeha F, Vivien D, Martinez de Lizarrondo S. Impact of Bradykinin Generation During Thrombolysis in Ischemic Stroke. Frontiers in Medicine. 5: 195. PMID 30018956 DOI: 10.3389/fmed.2018.00195  0.437
2018 Pasquet N, Douceau S, Naveau M, Lesept F, Louessard M, Lebouvier L, Hommet Y, Vivien D, Bardou I. Tissue-Type Plasminogen Activator Controlled Corticogenesis Through a Mechanism Dependent of NMDA Receptors Expressed on Radial Glial Cells. Cerebral Cortex (New York, N.Y. : 1991). PMID 29878094 DOI: 10.1093/cercor/bhy119  0.371
2018 Gilliot S, Sibon I, Mas JL, Moulin T, Béjot Y, Cordonnier C, Giroud M, Odou P, Bordet R, Vivien D, Leys D. Influence of on-going treatment with angiotensin-converting enzyme inhibitor or angiotensin receptor blocker on the outcome of patients treated with intravenous rt-PA for ischemic stroke. Journal of Neurology. PMID 29549467 DOI: 10.1007/s00415-018-8827-6  0.393
2018 Roth S, Singh V, Tiedt S, Schindler L, Huber G, Geerlof A, Antoine DJ, Anfray A, Orset C, Gauberti M, Fournier A, Holdt LM, Harris HE, Engelhardt B, Bianchi ME, ... Vivien D, et al. Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke. Science Translational Medicine. 10. PMID 29540615 DOI: 10.1126/Scitranslmed.Aao1313  0.608
2018 Gauberti M, Fournier AP, Docagne F, Vivien D, Martinez de Lizarrondo S. Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System. Theranostics. 8: 1195-1212. PMID 29507614 DOI: 10.7150/thno.22662  0.338
2018 Gakuba C, Gaberel T, Goursaud S, Bourges J, Di Palma C, Quenault A, de Lizarrondo SM, Vivien D, Gauberti M. General Anesthesia Inhibits the Activity of the "Glymphatic System". Theranostics. 8: 710-722. PMID 29344300 DOI: 10.7150/thno.19154  0.307
2017 Iglesias-Rey R, Rodríguez-Yáñez M, Rodríguez-Castro E, Pumar JM, Arias S, Santamaría M, López-Dequidt I, Hervella P, Correa-Paz C, Sobrino T, Vivien D, Campos F, Castellanos M, Castillo J. Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors. Translational Stroke Research. PMID 29116527 DOI: 10.1007/S12975-017-0584-9  0.351
2017 Pruvost M, Lépine M, Leonetti C, Etard O, Naveau M, Agin V, Docagne F, Maubert E, Ali C, Emery E, Vivien D. ADAMTS-4 in oligodendrocytes contributes to myelination with an impact on motor function. Glia. PMID 28850711 DOI: 10.1002/Glia.23207  0.629
2017 Vaur P, Brugg B, Mericskay M, Li Z, Schmidt MS, Vivien D, Orset C, Jacotot E, Brenner C, Duplus E. Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842432 DOI: 10.1096/Fj.201700221Rr  0.353
2017 Lecuyer M, Rubio M, Chollat C, Lecointre M, Jégou S, Leroux P, Cleren C, Leroux-Nicollet I, Marpeau L, Vivien D, Marret S, Gonzalez BJ. Experimental and clinical evidence of differential effects of magnesium sulfate on neuroprotection and angiogenesis in the fetal brain. Pharmacology Research & Perspectives. 5. PMID 28805973 DOI: 10.1002/prp2.315  0.328
2017 Vivien D. Can the benefits of rtPA treatment for stroke be improved? Revue Neurologique. 173: 566-571. PMID 28797689 DOI: 10.1016/j.neurol.2017.07.003  0.424
2017 Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, et al. The choroid plexus is a key cerebral invasion route for T cells after stroke. Acta Neuropathologica. PMID 28762187 DOI: 10.1007/S00401-017-1758-Y  0.583
2017 Labeyrie PE, Goulay R, Martinez de Lizarrondo S, Hébert M, Gauberti M, Maubert E, Delaunay B, Gory B, Signorelli F, Turjman F, Touzé E, Courthéoux P, Vivien D, Orset C. Vascular Tissue-Type Plasminogen Activator Promotes Intracranial Aneurysm Formation. Stroke. PMID 28754830 DOI: 10.1161/STROKEAHA.117.017305  0.324
2017 Goulay R, Naveau M, Gaberel T, Vivien D, Parcq J. Optimized tPA: A non-neurotoxic fibrinolytic agent for the drainage of intracerebral hemorrhages. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17719180. PMID 28741405 DOI: 10.1177/0271678X17719180  0.438
2017 Louessard M, Bardou I, Lemarchand E, Thiebaut AM, Parcq J, Leprince J, Terrisse A, Carraro V, Fafournoux P, Bruhat A, Orset C, Vivien D, Ali C, Roussel BD. Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death. Cell Death and Differentiation. PMID 28644439 DOI: 10.1038/cdd.2017.35  0.686
2017 Goulay R, Flament J, Gauberti M, Naveau M, Pasquet N, Gakuba C, Emery E, Hantraye P, Vivien D, Aron-Badin R, Gaberel T. Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate. Stroke. PMID 28526764 DOI: 10.1161/STROKEAHA.117.017014  0.386
2017 Martinez de Lizarrondo S, Gakuba C, Herbig BA, Repessé Y, Ali C, Denis CV, Lenting P, Touzé E, Diamond SL, Vivien D, Gauberti M. Potent Thrombolytic Effect of N-Acetylcysteine on Arterial Thrombi. Circulation. PMID 28487393 DOI: 10.1161/Circulationaha.117.027290  0.683
2017 Briens A, Bardou I, Lebas H, Miles LA, Parmer RJ, Vivien D, Docagne F. Astrocytes regulate the balance between plasminogen activation and plasmin clearance via cell-surface actin. Cell Discovery. 3: 17001. PMID 28417010 DOI: 10.1038/Celldisc.2017.1  0.372
2017 Roncal C, Martinez de Lizarrondo S, Salicio A, Chevilley A, Rodriguez JA, Rosell A, Couraud PO, Weksler B, Montaner J, Vivien D, Páramo JA, Orbe J. New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tPA. Cardiovascular Research. PMID 28379489 DOI: 10.1093/cvr/cvx069  0.359
2017 Quattromani MJ, Pruvost M, Guerreiro C, Backlund F, Englund E, Aspberg A, Jaworski T, Hakon J, Ruscher K, Kaczmarek L, Vivien D, Wieloch T. Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery. Molecular Neurobiology. PMID 28290150 DOI: 10.1007/S12035-017-0461-2  0.429
2017 Leonetti C, Macrez R, Pruvost M, Hommet Y, Bronsard J, Fournier A, Perrigault M, Machin I, Vivien D, Clemente D, De Castro F, Maubert E, Docagne F. Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination. Molecular Neurodegeneration. 12: 20. PMID 28231842 DOI: 10.1186/s13024-017-0160-5  0.308
2017 Lemarchant S, Wojciechowski S, Vivien D, Koistinaho J. ADAMTS-4 in central nervous system pathologies. Journal of Neuroscience Research. PMID 28084617 DOI: 10.1002/Jnr.24021  0.343
2017 Dhungana H, Huuskonen MT, Pihlajaniemi T, Heljasvaara R, Vivien D, Kanninen KM, Malm T, Koistinaho J, Lemarchant S. Lack of collagen XV is protective after ischemic stroke in mice. Cell Death & Disease. 8: e2541. PMID 28079884 DOI: 10.1038/Cddis.2016.456  0.385
2017 Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, ... ... Vivien D, et al. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restorative Neurology and Neuroscience. PMID 28059802 DOI: 10.3233/Rnn-160690  0.344
2017 Quenault A, Martinez de Lizarrondo S, Etard O, Gauberti M, Orset C, Haelewyn B, Segal HC, Rothwell PM, Vivien D, Touzé E, Ali C. Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack. Brain : a Journal of Neurology. 140: 146-157. PMID 28031221 DOI: 10.1093/Brain/Aww260  0.667
2016 Macrez R, Vivien D, Docagne F. [Role of endothelial NMDA receptors in a mouse model of multiple sclerosis]. Medecine Sciences : M/S. 32: 1068-1071. PMID 28044968 DOI: 10.1051/medsci/20163212008  0.333
2016 Lesept F, Chevilley A, Jezequel J, Ladépêche L, Macrez R, Aimable M, Lenoir S, Bertrand T, Rubrecht L, Galea P, Lebouvier L, Petersen KU, Hommet Y, Maubert E, Ali C, ... ... Vivien D, et al. Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors. Cell Death & Disease. 7: e2466. PMID 27831563 DOI: 10.1038/cddis.2016.279  0.691
2016 Leys D, Hommet Y, Jacquet C, Moulin S, Sibon I, Mas JL, Moulin T, Giroud M, Sagnier S, Cordonnier C, Medeiros de Bustos E, Turc G, Ronzière T, Bejot Y, Detante O, ... ... Vivien D, et al. Proportion of single-chain recombinant tissue plasminogen activator and outcome after stroke. Neurology. PMID 27815401 DOI: 10.1212/WNL.0000000000003399  0.345
2016 Hébert M, Anfray A, Chevilley A, Martinez de Lizarrondo S, Quenault A, Louessard M, Roussel BD, Obiang P, Save E, Orset C, Maubert E, Vivien D, Agin V. Distant Space Processing is Controlled by tPA-dependent NMDA Receptor Signaling in the Entorhinal Cortex. Cerebral Cortex (New York, N.Y. : 1991). PMID 27613436 DOI: 10.1093/cercor/bhw275  0.379
2016 Macrez R, Stys PK, Vivien D, Lipton SA, Docagne F. Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities. The Lancet. Neurology. 15: 1089-1102. PMID 27571160 DOI: 10.1016/S1474-4422(16)30165-X  0.366
2016 Marcos-Contreras OA, Martinez de Lizarrondo S, Bardou I, Orset C, Pruvost M, Anfray A, Frigout Y, Hommet Y, Lebouvier L, Montaner J, Vivien D, Gauberti M. Hyperfibrinolysis increases blood brain barrier permeability by a plasmin and bradykinin-dependent mechanism. Blood. PMID 27531677 DOI: 10.1182/blood-2016-03-705384  0.421
2016 Macrez R, Ortega MC, Bardou I, Mehra A, Fournier A, Van der Pol SM, Haelewyn B, Maubert E, Lesept F, Chevilley A, de Castro F, De Vries HE, Vivien D, Clemente D, Docagne F. Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. PMID 27435092 DOI: 10.1093/brain/aww172  0.355
2016 Orset C, Haelewyn B, Allan SM, Ansar S, Campos F, Cho TH, Durand A, El Amki M, Fatar M, Garcia-Yébenes I, Gauberti M, Grudzenski S, Lizasoain I, Lo E, Macrez R, ... ... Vivien D, et al. Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis. Stroke; a Journal of Cerebral Circulation. PMID 27032444 DOI: 10.1161/Strokeaha.116.012238  0.388
2016 Briens A, Gauberti M, Parcq J, Montaner J, Vivien D, Martinez de Lizarrondo S. Nano-zymography Using Laser-Scanning Confocal Microscopy Unmasks Proteolytic Activity of Cell-Derived Microparticles. Theranostics. 6: 610-26. PMID 27022410 DOI: 10.7150/thno.13757  0.357
2016 Mollereau B, Rzechorzek NM, Roussel BD, Sedru M, Van den Brink D, Bailly-Maitre B, Palladino F, Medinas DB, Domingos PM, Hunot S, Chandran S, Birman S, Baron T, Vivien D, Duarte CB, et al. Adaptive Preconditioning in Neurological Diseases - Therapeutic Insights from Proteostatic Perturbations. Brain Research. PMID 26923166 DOI: 10.1016/J.Brainres.2016.02.033  0.313
2015 Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661169 DOI: 10.1177/0271678X15606714  0.402
2015 Hébert M, Lesept F, Vivien D, Macrez R. The story of an exceptional serine protease, tissue-type plasminogen activator (tPA). Revue Neurologique. PMID 26626577 DOI: 10.1016/j.neurol.2015.10.002  0.465
2015 Chevilley A, Lesept F, Lenoir S, Ali C, Parcq J, Vivien D. Impacts of tissue-type plasminogen activator (tPA) on neuronal survival. Frontiers in Cellular Neuroscience. 9: 415. PMID 26528141 DOI: 10.3389/fncel.2015.00415  0.713
2015 Mehra A, Ali C, Parcq J, Vivien D, Docagne F. The plasminogen activation system in neuroinflammation. Biochimica Et Biophysica Acta. PMID 26493446 DOI: 10.1016/j.bbadis.2015.10.011  0.695
2015 Bertrand T, Lesept F, Chevilley A, Lenoir S, Aimable M, Briens A, Hommet Y, Bardou I, Parcq J, Vivien D. Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR. Cell Death & Disease. 6: e1924. PMID 26469972 DOI: 10.1038/cddis.2015.296  0.42
2015 Louessard M, Lacroix A, Martineau M, Mondielli G, Montagne A, Lesept F, Lambolez B, Cauli B, Mothet JP, Vivien D, Maubert E. Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons. Molecular Neurobiology. PMID 26377106 DOI: 10.1007/S12035-015-9432-7  0.408
2015 Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, ... ... Vivien D, et al. Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia. Science Translational Medicine. 7: 299ra121. PMID 26246166 DOI: 10.1126/Scitranslmed.Aaa9853  0.381
2015 Lemarchand E, Maubert E, Haelewyn B, Ali C, Rubio M, Vivien D. Stressed neurons protect themselves by a tissue-type plasminogen activator-mediated EGFR-dependent mechanism. Cell Death and Differentiation. PMID 26068590 DOI: 10.1038/cdd.2015.76  0.482
2015 Macrez R, Vivien D, Docagne F. Letter by Macrez et al. Regarding Article, "Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke". Stroke; a Journal of Cerebral Circulation. 46: e177. PMID 26022638 DOI: 10.1161/STROKEAHA.115.009670  0.388
2015 Lemarchand E, Gauberti M, Martinez de Lizarrondo S, Villain H, Repessé Y, Montagne A, Vivien D, Ali C, Rubio M. Impact of alcohol consumption on the outcome of ischemic stroke and thrombolysis: role of the hepatic clearance of tissue-type plasminogen activator. Stroke; a Journal of Cerebral Circulation. 46: 1641-50. PMID 25922513 DOI: 10.1161/STROKEAHA.114.007143  0.69
2015 Joshi AU, Orset C, Engelhardt B, Baumgart-Vogt E, Gerriets T, Vivien D, Kanse SM. Deficiency of Factor VII activating protease alters the outcome of ischemic stroke in mice. The European Journal of Neuroscience. 41: 965-75. PMID 25615590 DOI: 10.1111/Ejn.12830  0.771
2015 Gauberti M, Vivien D. Letter by Gauberti and Vivien regarding article, "amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice". Stroke; a Journal of Cerebral Circulation. 46: e50-1. PMID 25586834 DOI: 10.1161/STROKEAHA.114.008071  0.411
2015 Wyseure T, Rubio M, Denorme F, Martinez de Lizarrondo S, Peeters M, Gils A, De Meyer SF, Vivien D, Declerck PJ. Innovative thrombolytic strategy using a heterodimer diabody against TAFI and PAI-1 in mouse models of thrombosis and stroke. Blood. 125: 1325-32. PMID 25540192 DOI: 10.1182/blood-2014-07-588319  0.387
2015 Merino-Zamorano C, Hernández-Guillamon M, Jullienne A, Le Béhot A, Bardou I, Parés M, Fernández-Cadenas I, Giralt D, Carrera C, Ribó M, Vivien D, Ali C, Rosell A, Montaner J. NURR1 involvement in recombinant tissue-type plasminogen activator treatment complications after ischemic stroke. Stroke; a Journal of Cerebral Circulation. 46: 477-84. PMID 25503547 DOI: 10.1161/STROKEAHA.114.006826  0.81
2015 Docagne F, Parcq J, Lijnen R, Ali C, Vivien D. Understanding the functions of endogenous and exogenous tissue-type plasminogen activator during stroke. Stroke; a Journal of Cerebral Circulation. 46: 314-20. PMID 25395410 DOI: 10.1161/STROKEAHA.114.006698  0.736
2015 Balossier A, Orset C, Etard O, Gakuba C, Emery E, Vivien D. Effects of epidural cortical stimulation on motor recovery after a primary motor cortex ischemic stroke: preliminary results in a non-human primate model Brain Stimulation. 8: 430. DOI: 10.1016/J.Brs.2015.01.371  0.325
2014 Gauberti M, Montagne A, Quenault A, Vivien D. Molecular magnetic resonance imaging of brain-immune interactions. Frontiers in Cellular Neuroscience. 8: 389. PMID 25505871 DOI: 10.3389/fncel.2014.00389  0.329
2014 Gaberel T, Gakuba C, Goulay R, Martinez De Lizarrondo S, Hanouz JL, Emery E, Touze E, Vivien D, Gauberti M. Impaired glymphatic perfusion after strokes revealed by contrast-enhanced MRI: a new target for fibrinolysis? Stroke; a Journal of Cerebral Circulation. 45: 3092-6. PMID 25190438 DOI: 10.1161/STROKEAHA.114.006617  0.361
2014 Gaberel T, Montagne A, Lesept F, Gauberti M, Lemarchand E, Orset C, Goulay R, Bertrand T, Emery E, Vivien D. Urokinase versus Alteplase for intraventricular hemorrhage fibrinolysis. Neuropharmacology. 85: 158-65. PMID 24846802 DOI: 10.1016/j.neuropharm.2014.05.001  0.399
2014 Raoult E, Bénard M, Komuro H, Lebon A, Vivien D, Fournier A, Vaudry H, Vaudry D, Galas L. Cortical-layer-specific effects of PACAP and tPA on interneuron migration during post-natal development of the cerebellum. Journal of Neurochemistry. 130: 241-54. PMID 24646324 DOI: 10.1111/Jnc.12714  0.313
2014 Lemarchant S, Pruvost M, Hébert M, Gauberti M, Hommet Y, Briens A, Maubert E, Gueye Y, Féron F, Petite D, Mersel M, do Rego JC, Vaudry H, Koistinaho J, Ali C, ... ... Vivien D, et al. tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiology of Disease. 66: 28-42. PMID 24576594 DOI: 10.1016/J.Nbd.2014.02.005  0.658
2014 Le Behot A, Gauberti M, Martinez De Lizarrondo S, Montagne A, Lemarchand E, Repesse Y, Guillou S, Denis CV, Maubert E, Orset C, Vivien D. GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice. Blood. 123: 3354-63. PMID 24553181 DOI: 10.1182/blood-2013-12-543074  0.314
2014 Gauberti M, Martinez de Lizarrondo S, Orset C, Vivien D. Lack of secondary microthrombosis after thrombin-induced stroke in mice and non-human primates. Journal of Thrombosis and Haemostasis : Jth. 12: 409-14. PMID 24354644 DOI: 10.1111/jth.12487  0.42
2014 Orbe J, Roncal C, Rodriguez J, Salicio A, Montaner J, Rosell A, Martinez De Lizarrondo S, Vivien D, Paramo J. P218tPA in combination with MMP-10 a new effective strategy for thrombolysis in ischemic stroke with neuroprotective effect Cardiovascular Research. 103: S38.5-S39. DOI: 10.1093/CVR/CVU082.151  0.404
2013 Rosell A, Agin V, Rahman M, Morancho A, Ali C, Koistinaho J, Wang X, Vivien D, Schwaninger M, Montaner J. Distal occlusion of the middle cerebral artery in mice: are we ready to assess long-term functional outcome? Translational Stroke Research. 4: 297-307. PMID 24323300 DOI: 10.1007/S12975-012-0234-1  0.652
2013 Lemarchant S, Pruvost M, Montaner J, Emery E, Vivien D, Kanninen K, Koistinaho J. ADAMTS proteoglycanases in the physiological and pathological central nervous system. Journal of Neuroinflammation. 10: 133. PMID 24176075 DOI: 10.1186/1742-2094-10-133  0.336
2013 Gakuba C, Gauberti M, Vivien D. Endovascular treatment for acute ischemic stroke. The New England Journal of Medicine. 368: 2430-1. PMID 23782184 DOI: 10.1056/NEJMc1304759#SA2  0.357
2013 Gauberti M, Montagne A, Marcos-Contreras OA, Le Béhot A, Maubert E, Vivien D. Ultra-sensitive molecular MRI of vascular cell adhesion molecule-1 reveals a dynamic inflammatory penumbra after strokes. Stroke; a Journal of Cerebral Circulation. 44: 1988-96. PMID 23743972 DOI: 10.1161/STROKEAHA.111.000544  0.395
2013 Parcq J, Bertrand T, Baron AF, Hommet Y, Anglès-Cano E, Vivien D. Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain. Journal of Thrombosis and Haemostasis : Jth. 11: 539-46. PMID 23301636 DOI: 10.1111/jth.12128  0.323
2013 Gaberel T, Macrez R, Gauberti M, Montagne A, Hebert M, Petersen KU, Touze E, Agin V, Emery E, Ali C, Vivien D. Immunotherapy blocking the tissue plasminogen activator-dependent activation of N-methyl-D-aspartate glutamate receptors improves hemorrhagic stroke outcome. Neuropharmacology. 67: 267-71. PMID 23219658 DOI: 10.1016/j.neuropharm.2012.11.023  0.745
2013 Henry VJ, Lecointre M, Laudenbach V, Ali C, Macrez R, Jullienne A, Berezowski V, Carmeliet P, Vivien D, Marret S, Gonzalez BJ, Leroux P. High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate. Neurobiology of Disease. 50: 201-8. PMID 23103420 DOI: 10.1016/j.nbd.2012.10.020  0.809
2012 Kaindl AM, Degos V, Peineau S, Gouadon E, Chhor V, Loron G, Le Charpentier T, Josserand J, Ali C, Vivien D, Collingridge GL, Lombet A, Issa L, Rene F, Loeffler JP, et al. Activation of microglial N-methyl-D-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain. Annals of Neurology. 72: 536-49. PMID 23109148 DOI: 10.1002/ana.23626  0.725
2012 Obiang P, Macrez R, Jullienne A, Bertrand T, Lesept F, Ali C, Maubert E, Vivien D, Agin V. GluN2D subunit-containing NMDA receptors control tissue plasminogen activator-mediated spatial memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12726-34. PMID 22972996 DOI: 10.1523/JNEUROSCI.6202-11.2012  0.805
2012 Vivien D, Ali C. Traumatic brain injury: tissue-type plasminogen activator--harmful or beneficial? Nature Reviews. Neurology. 8: 538-9. PMID 22964508 DOI: 10.1038/nrneurol.2012.192  0.702
2012 El Amki M, Lerouet D, Coqueran B, Curis E, Orset C, Vivien D, Plotkine M, Marchand-Leroux C, Margaill I. Experimental modeling of recombinant tissue plasminogen activator effects after ischemic stroke. Experimental Neurology. 238: 138-44. PMID 22921458 DOI: 10.1016/j.expneurol.2012.08.005  0.368
2012 Montagne A, Hébert M, Jullienne A, Lesept F, Le Béhot A, Louessard M, Gauberti M, Orset C, Ali C, Agin V, Maubert E, Vivien D. Memantine improves safety of thrombolysis for stroke. Stroke; a Journal of Cerebral Circulation. 43: 2774-81. PMID 22879098 DOI: 10.1161/STROKEAHA.112.669374  0.821
2012 Montagne A, Gauberti M, Macrez R, Jullienne A, Briens A, Raynaud JS, Louin G, Buisson A, Haelewyn B, Docagne F, Defer G, Vivien D, Maubert E. Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders. Neuroimage. 63: 760-70. PMID 22813950 DOI: 10.1016/j.neuroimage.2012.07.018  0.783
2012 Parcq J, Bertrand T, Montagne A, Baron AF, Macrez R, Billard JM, Briens A, Hommet Y, Wu J, Yepes M, Lijnen HR, Dutar P, Anglés-Cano E, Vivien D. Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity. Cell Death and Differentiation. 19: 1983-91. PMID 22743997 DOI: 10.1038/cdd.2012.86  0.419
2012 Cassé F, Bardou I, Danglot L, Briens A, Montagne A, Parcq J, Alahari A, Galli T, Vivien D, Docagne F. Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5186-99. PMID 22496564 DOI: 10.1523/Jneurosci.5296-11.2012  0.417
2012 Gauberti M, Obiang P, Guedin P, Balossier A, Gakuba C, Diependaele AS, Chazalviel L, Vivien D, Young AR, Agin V, Orset C. Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study. Cerebrovascular Diseases (Basel, Switzerland). 33: 329-39. PMID 22343114 DOI: 10.1159/000335309  0.372
2012 Danglot L, Zylbersztejn K, Petkovic M, Gauberti M, Meziane H, Combe R, Champy MF, Birling MC, Pavlovic G, Bizot JC, Trovero F, Della Ragione F, Proux-Gillardeaux V, Sorg T, Vivien D, et al. Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1962-8. PMID 22323709 DOI: 10.1523/Jneurosci.4436-11.2012  0.342
2012 Lemarchant S, Docagne F, Emery E, Vivien D, Ali C, Rubio M. tPA in the injured central nervous system: different scenarios starring the same actor? Neuropharmacology. 62: 749-56. PMID 22079561 DOI: 10.1016/j.neuropharm.2011.10.020  0.712
2012 Macrez R, Defer G, Vivien D, Ali C. Immunotherapy for Stroke: A New Hope of Treatment (P07.004) Neurology. 78: P07.004-P07.004. DOI: 10.1212/WNL.78.1_MEETINGABSTRACTS.P07.004  0.492
2011 Orbe J, Barrenetxe J, Rodriguez JA, Vivien D, Orset C, Parks WC, Birkland TP, Serrano R, Purroy A, Martinez de Lizarrondo S, Angles-Cano E, Páramo JA. Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. Circulation. 124: 2909-19. PMID 22104553 DOI: 10.1161/CIRCULATIONAHA.111.047100  0.35
2011 Jullienne A, Montagne A, Orset C, Lesept F, Jane DE, Monaghan DT, Maubert E, Vivien D, Ali C. Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo. Molecular Neurodegeneration. 6: 68. PMID 21975018 DOI: 10.1186/1750-1326-6-68  0.824
2011 Raoult E, Roussel BD, Bénard M, Lefebvre T, Ravni A, Ali C, Vivien D, Komuro H, Fournier A, Vaudry H, Vaudry D, Galas L. Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the expression and the release of tissue plasminogen activator (tPA) in neuronal cells: involvement of tPA in the neuroprotective effect of PACAP. Journal of Neurochemistry. 119: 920-31. PMID 21919910 DOI: 10.1111/J.1471-4159.2011.07486.X  0.691
2011 Rubio M, Villain H, Docagne F, Roussel BD, Ramos JA, Vivien D, Fernandez-Ruiz J, Ali C. Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. Plos One. 6: e23690. PMID 21886913 DOI: 10.1371/journal.pone.0023690  0.678
2011 Vivien D, Gauberti M, Montagne A, Defer G, Touzé E. Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 2119-34. PMID 21878948 DOI: 10.1038/jcbfm.2011.127  0.383
2011 Gakuba C, Gauberti M, Mazighi M, Defer G, Hanouz JL, Vivien D. Preclinical evidence toward the use of ketamine for recombinant tissue-type plasminogen activator-mediated thrombolysis under anesthesia or sedation. Stroke; a Journal of Cerebral Circulation. 42: 2947-9. PMID 21817137 DOI: 10.1161/STROKEAHA.111.620468  0.43
2011 Meissirel C, Ruiz de Almodovar C, Knevels E, Coulon C, Chounlamountri N, Segura I, de Rossi P, Vinckier S, Anthonis K, Deléglise B, de Mol M, Ali C, Dassonville K, Loyens E, Honnorat J, ... ... Vivien D, et al. VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 13782-7. PMID 21804034 DOI: 10.1073/Pnas.1100341108  0.667
2011 Macrez R, Obiang P, Gauberti M, Roussel B, Baron A, Parcq J, Cassé F, Hommet Y, Orset C, Agin V, Bezin L, Berrocoso TG, Petersen KU, Montaner J, Maubert E, ... Vivien D, et al. Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis. Stroke; a Journal of Cerebral Circulation. 42: 2315-22. PMID 21680906 DOI: 10.1161/STROKEAHA.110.606293  0.733
2011 Roussel BD, Mysiorek C, Rouhiainen A, Jullienne A, Parcq J, Hommet Y, Culot M, Berezowski V, Cecchelli R, Rauvala H, Vivien D, Ali C. HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator. Journal of Cell Science. 124: 2070-6. PMID 21610098 DOI: 10.1242/jcs.084392  0.834
2011 Correa F, Gauberti M, Parcq J, Macrez R, Hommet Y, Obiang P, Hernangómez M, Montagne A, Liot G, Guaza C, Maubert E, Ali C, Vivien D, Docagne F. Tissue plasminogen activator prevents white matter damage following stroke. The Journal of Experimental Medicine. 208: 1229-42. PMID 21576385 DOI: 10.1084/jem.20101880  0.73
2011 Macrez R, Ali C, Toutirais O, Le Mauff B, Defer G, Dirnagl U, Vivien D. Stroke and the immune system: from pathophysiology to new therapeutic strategies. The Lancet. Neurology. 10: 471-80. PMID 21511199 DOI: 10.1016/S1474-4422(11)70066-7  0.685
2011 Obiang P, Maubert E, Bardou I, Nicole O, Launay S, Bezin L, Vivien D, Agin V. Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF. Neurobiology of Learning and Memory. 96: 121-9. PMID 21440650 DOI: 10.1016/j.nlm.2011.03.004  0.305
2010 Macrez R, Bezin L, Le Mauff B, Ali C, Vivien D. Functional occurrence of the interaction of tissue plasminogen activator with the NR1 Subunit of N-methyl-D-aspartate receptors during stroke. Stroke; a Journal of Cerebral Circulation. 41: 2950-5. PMID 20966414 DOI: 10.1161/STROKEAHA.110.592360  0.736
2010 Baron A, Hommet Y, Cassé F, Vivien D. Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 102: 539-47. PMID 20636282 DOI: 10.1042/BC20100072  0.43
2010 Reijerkerk A, Kooij G, van der Pol SM, Leyen T, Lakeman K, van Het Hof B, Vivien D, de Vries HE. The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. Journal of Neurochemistry. 113: 447-53. PMID 20085611 DOI: 10.1111/j.1471-4159.2010.06598.x  0.414
2010 Baron A, Montagne A, Cassé F, Launay S, Maubert E, Ali C, Vivien D. NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Cell Death and Differentiation. 17: 860-71. PMID 19911010 DOI: 10.1038/cdd.2009.172  0.449
2010 Macrez R, Obiang P, Gauberti M, Baron A, Roussel B, Parcq J, Orset C, Hommet Y, Bezin L, Berrocoso TG, Montaner J, Agin V, Maubert E, Vivien D, Ali C. An immunotherapeutic strategy targeting neurotoxicity of tPA: A new hope for the treatment of stroke F1000research. 1. DOI: 10.7490/F1000Research.570.1  0.346
2009 Vivien D, Gauberti M, Guedin P, Anglés-Cano E. [Cerebral ischemia (2), How to neutralize the neurotoxic effects of tPA]. Mã©Decine Sciences : M/S. 25: 855-7. PMID 19849989 DOI: 10.1051/medsci/20092510855  0.343
2009 Anglés-Cano E, Vivien D. [Cellular microparticles, potential useful biomarkers in the identification of cerebrovascular accidents]. Mã©Decine Sciences : M/S. 25: 843-6. PMID 19849987 DOI: 10.1051/medsci/20092510843  0.397
2009 Roussel BD, Hommet Y, Macrez R, Schulz T, Petersen KU, Berezowski V, Cecchelli R, Ali C, Vivien D. PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAalpha1) prevents the passage of tissue-type plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity. Thrombosis and Haemostasis. 102: 606-8. PMID 19718485 DOI: 10.1160/TH09-02-0114  0.689
2009 Culot M, Mysiorek C, Renftel M, Roussel BD, Hommet Y, Vivien D, Cecchelli R, Fenart L, Berezowski V, Dehouck MP, Lundquist S. Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Research. 1294: 144-52. PMID 19631615 DOI: 10.1016/j.brainres.2009.07.035  0.404
2009 Roussel BD, Macrez R, Jullienne A, Agin V, Maubert E, Dauphinot L, Potier MC, Plawinski L, Castel H, Hommet Y, Munuera J, Montaner J, Yepes M, Ali C, Vivien D. Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Brain : a Journal of Neurology. 132: 2219-30. PMID 19574439 DOI: 10.1093/brain/awp162  0.817
2009 Legros H, Launay S, Roussel BD, Marcou-Labarre A, Calbo S, Catteau J, Leroux P, Boyer O, Ali C, Marret S, Vivien D, Laudenbach V. Newborn- and adult-derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1146-58. PMID 19367295 DOI: 10.1038/Jcbfm.2009.39  0.679
2009 Yepes M, Roussel BD, Ali C, Vivien D. Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Trends in Neurosciences. 32: 48-55. PMID 18963068 DOI: 10.1016/j.tins.2008.09.006  0.723
2008 Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D. Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. Journal of Cell Science. 121: 3357-65. PMID 18796535 DOI: 10.1242/Jcs.031872  0.722
2008 Reijerkerk A, Kooij G, van der Pol SM, Leyen T, van Het Hof B, Couraud PO, Vivien D, Dijkstra CD, de Vries HE. Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. Journal of Immunology (Baltimore, Md. : 1950). 181: 3567-74. PMID 18714030 DOI: 10.4049/Jimmunol.181.5.3567  0.372
2008 Launay S, Maubert E, Lebeurrier N, Tennstaedt A, Campioni M, Docagne F, Gabriel C, Dauphinot L, Potier MC, Ehrmann M, Baldi A, Vivien D. HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival. Cell Death and Differentiation. 15: 1408-16. PMID 18551132 DOI: 10.1038/cdd.2008.82  0.367
2008 Lopez-Atalaya JP, Roussel BD, Levrat D, Parcq J, Nicole O, Hommet Y, Benchenane K, Castel H, Leprince J, To Van D, Bureau R, Rault S, Vaudry H, Petersen KU, Santos JS, ... ... Vivien D, et al. Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1212-21. PMID 18334994 DOI: 10.1038/jcbfm.2008.14  0.81
2008 Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular Diseases (Basel, Switzerland). 25: 268-78. PMID 18292653 DOI: 10.1159/000118039  0.595
2008 Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U, Keezer MR, Yu AYX, et al. EUSI-ESO News Cerebrovascular Diseases. 25: 288-288. DOI: 10.1159/000122836  0.445
2007 Young AR, Ali C, Duretête A, Vivien D. Neuroprotection and stroke: time for a compromise. Journal of Neurochemistry. 103: 1302-9. PMID 17727635 DOI: 10.1111/j.1471-4159.2007.04866.x  0.676
2007 Orset C, Macrez R, Young AR, Panthou D, Angles-Cano E, Maubert E, Agin V, Vivien D. Mouse model of in situ thromboembolic stroke and reperfusion. Stroke; a Journal of Cerebral Circulation. 38: 2771-8. PMID 17702959 DOI: 10.1161/STROKEAHA.107.487520  0.463
2007 Cacquevel M, Launay S, Castel H, Benchenane K, Chéenne S, Buée L, Moons L, Delacourte A, Carmeliet P, Vivien D. Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms. Neurobiology of Disease. 27: 164-73. PMID 17566751 DOI: 10.1016/J.Nbd.2007.04.004  0.709
2007 López-Atalaya JP, Roussel BD, Ali C, Maubert E, Petersen KU, Berezowski V, Cecchelli R, Orset C, Vivien D. Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects. Stroke; a Journal of Cerebral Circulation. 38: 1036-43. PMID 17325305 DOI: 10.1161/01.STR.0000258100.04923.84  0.729
2007 Benchenane K, Castel H, Boulouard M, Bluthé R, Fernandez-Monreal M, Roussel BD, Lopez-Atalaya JP, Butt-Gueulle S, Agin V, Maubert E, Dantzer R, Touzani O, Dauphin F, Vivien D, Ali C. Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory. Journal of Cell Science. 120: 578-85. PMID 17244650 DOI: 10.1242/Jcs.03354  0.812
2007 Docagne F, Muñetón V, Clemente D, Ali C, Loría F, Correa F, Hernangómez M, Mestre L, Vivien D, Guaza C. Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation. Molecular and Cellular Neurosciences. 34: 551-61. PMID 17229577 DOI: 10.1016/j.mcn.2006.12.005  0.638
2006 Liot G, Roussel BD, Lebeurrier N, Benchenane K, López-Atalaya JP, Vivien D, Ali C. Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity. Journal of Neurochemistry. 98: 1458-64. PMID 16800849 DOI: 10.1111/j.1471-4159.2006.03982.x  0.818
2006 Meairs S, Wahlgren N, Dirnagl U, Lindvall O, Rothwell P, Baron JC, Hossmann K, Engelhardt B, Ferro J, McCulloch J, Kaste M, Endres M, Koistinaho J, Planas A, Vivien D, et al. Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovascular Diseases (Basel, Switzerland). 22: 75-82. PMID 16790993 DOI: 10.1159/000093098  0.562
2006 Vivien D, Ali C. Transforming growth factor-beta signalling in brain disorders. Cytokine & Growth Factor Reviews. 17: 121-8. PMID 16271500 DOI: 10.1016/j.cytogfr.2005.09.011  0.691
2006 López-Atalaya J, Roussel B, Levrat D, Nicole O, Benchenane K, Rault S, Vaudry H, Petersen K, Ali C, Vivien D. ID: 96 Molecular requirements for modulation of NMDA receptor signaling by tissue-type plasminogen activator Journal of Thrombosis and Haemostasis. 4: 185-185. DOI: 10.1111/J.1538-7836.2006.00096.X  0.722
2006 ORSET C, HAELEWYN B, YOUNG A, ALI C, VIVIEN D. ID: 66 In situ clot formation: an original model for pre-clinical evaluation of stroke therapy Journal of Thrombosis and Haemostasis. 4: 216-216. DOI: 10.1111/j.1538-7836.2006.00066.x  0.322
2005 Lesné S, Ali C, Gabriel C, Croci N, MacKenzie ET, Glabe CG, Plotkine M, Marchand-Verrecchia C, Vivien D, Buisson A. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9367-77. PMID 16221845 DOI: 10.1523/Jneurosci.0849-05.2005  0.803
2005 Lebeurrier N, Liot G, Lopez-Atalaya JP, Orset C, Fernandez-Monreal M, Sonderegger P, Ali C, Vivien D. The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo. Molecular and Cellular Neurosciences. 30: 552-8. PMID 16209928 DOI: 10.1016/J.Mcn.2005.09.005  0.753
2005 Lin AH, Luo J, Mondshein LH, ten Dijke P, Vivien D, Contag CH, Wyss-Coray T. Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. Journal of Immunology (Baltimore, Md. : 1950). 175: 547-54. PMID 15972691 DOI: 10.4049/Jimmunol.175.1.547  0.362
2005 Benchenane K, Berezowski V, Ali C, Fernández-Monreal M, López-Atalaya JP, Brillault J, Chuquet J, Nouvelot A, MacKenzie ET, Bu G, Cecchelli R, Touzani O, Vivien D. Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis. Circulation. 111: 2241-9. PMID 15851587 DOI: 10.1161/01.CIR.0000163542.48611.A2  0.813
2005 Gaertner RF, Wyss-Coray T, Von Euw D, Lesné S, Vivien D, Lacombe P. Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities. Neurobiology of Disease. 19: 38-46. PMID 15837559 DOI: 10.1016/J.Nbd.2004.11.008  0.325
2005 Benchenane K, Berezowski V, Fernández-Monreal M, Brillault J, Valable S, Dehouck MP, Cecchelli R, Vivien D, Touzani O, Ali C. Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process. Stroke; a Journal of Cerebral Circulation. 36: 1065-70. PMID 15817895 DOI: 10.1161/01.STR.0000163050.39122.4f  0.809
2005 Lesné S, Gabriel C, Nelson DA, White E, Mackenzie ET, Vivien D, Buisson A. Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. The Journal of Biological Chemistry. 280: 24941-7. PMID 15797869 DOI: 10.1074/Jbc.M413495200  0.794
2005 Vivien D. tPA as an ‘interface’ between blood and brain Journal of Cerebral Blood Flow & Metabolism. 25: S687-S687. DOI: 10.1038/SJ.JCBFM.9591524.0687  0.478
2005 Castel H, Benchenane K, Fernandez-Monreal M, Lopez-Atalaya J, Bluthé R, Boulouard M, Dauphin F, MacKenzie ET, Dantzer R, Touzani O, Ali C, Vivien D. Physiological and pathological implications of the tPA/NR1 interaction: An immunization-based investigation Journal of Cerebral Blood Flow & Metabolism. 25: S579-S579. DOI: 10.1038/Sj.Jcbfm.9591524.0579  0.81
2005 Atalaya JL, Benchenane K, Castel H, Ali C, Petersen K, Vivien D. Desmoteplase (DSPA) does not interact with or cleave the NMDA receptor NR1 subunit: Possible molecular basis for improved tolerability in treatment of acute ischemic stroke Journal of Cerebral Blood Flow & Metabolism. 25: S578-S578. DOI: 10.1038/SJ.JCBFM.9591524.0578  0.784
2005 Lebeurrier N, Liot G, Lopez-Atalaya J, Fernandez-Monreal M, Sonderegger P, Vivien D, Ali C. Neuroprotective activity of neuroserpin against NMDA receptor-mediated excitotoxicity Journal of Cerebral Blood Flow & Metabolism. 25: S455-S455. DOI: 10.1038/Sj.Jcbfm.9591524.0455  0.501
2005 Benchenane K, Ali C, Brillault J, Berezowski V, Fernandez-Monreal M, Lopez-Attalaya JP, Chuquet J, Nouvelot A, MacKenzie ET, Dehouck M, Cecchelli R, Vivien D, Touzani O. Tissue-type plasminogen activator crosses the intact blood-brain barrier by LRP-mediated transcytosis: A phenomenon that is switched during oxygen glucose deprivation to an increased and LRP-independent process Journal of Cerebral Blood Flow & Metabolism. 25: S140-S140. DOI: 10.1038/sj.jcbfm.9591524.0140  0.831
2005 Debroas E, Ali C, Lebeurrier N, Vivien D, Duval D. Neuroprotective activity of glucocorticoids against NMDA toxicity in mouse cortical neuron-astrocyte cultures: Potential role of the tPA-PAI-1 axis Journal of Cerebral Blood Flow & Metabolism. 25: S22-S22. DOI: 10.1038/sj.jcbfm.9591524.0022  0.457
2004 Liot G, Benchenane K, Léveillé F, López-Atalaya JP, Fernández-Monreal M, Ruocco A, Mackenzie ET, Buisson A, Ali C, Vivien D. 2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 1153-9. PMID 15529015 DOI: 10.1097/01.WCB.0000134476.93809.75  0.828
2004 Fernández-Monreal M, López-Atalaya JP, Benchenane K, Cacquevel M, Dulin F, Le Caer JP, Rossier J, Jarrige AC, Mackenzie ET, Colloc'h N, Ali C, Vivien D. Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. The Journal of Biological Chemistry. 279: 50850-6. PMID 15448144 DOI: 10.1074/jbc.M407069200  0.813
2004 Lebeurrier N, Vivien D, Ali C. The complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management? Expert Opinion On Therapeutic Targets. 8: 309-20. PMID 15268626 DOI: 10.1517/14728222.8.4.309  0.713
2004 Docagne F, Gabriel C, Lebeurrier N, Lesné S, Hommet Y, Plawinski L, Mackenzie ET, Vivien D. Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription. The Biochemical Journal. 383: 393-9. PMID 15242331 DOI: 10.1042/Bj20040682  0.316
2004 Liot G, Gabriel C, Cacquevel M, Ali C, MacKenzie ET, Buisson A, Vivien D. Neurotrophin-3-induced PI-3 kinase/Akt signaling rescues cortical neurons from apoptosis. Experimental Neurology. 187: 38-46. PMID 15081586 DOI: 10.1016/j.expneurol.2004.01.002  0.785
2004 Fernández-Monreal M, López-Atalaya JP, Benchenane K, Léveillé F, Cacquevel M, Plawinski L, MacKenzie ET, Bu G, Buisson A, Vivien D. Is tissue-type plasminogen activator a neuromodulator? Molecular and Cellular Neurosciences. 25: 594-601. PMID 15080889 DOI: 10.1016/j.mcn.2003.11.002  0.801
2004 Benchenane K, López-Atalaya JP, Fernández-Monreal M, Touzani O, Vivien D. Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. Trends in Neurosciences. 27: 155-60. PMID 15036881 DOI: 10.1016/j.tins.2003.12.011  0.822
2004 Cacquevel M, Chéenne S, Castel H, Benavides J, Pradier L, Vivien D. P1-160 The role of the tissue-type plasminogen activator in the course of amyloid accumulation Neurobiology of Aging. 25: S141. DOI: 10.1016/S0197-4580(04)80473-1  0.312
2003 Buisson A, Lesne S, Docagne F, Ali C, Nicole O, MacKenzie ET, Vivien D. Transforming growth factor-beta and ischemic brain injury. Cellular and Molecular Neurobiology. 23: 539-50. PMID 14514014 DOI: 10.1023/A:1025072013107  0.818
2003 Docagne F, Ali C, Lesne S, Nicole O, MacKenzie ET, Buisson A, Vivien D. [Does transforming growth factor-beta (TGF-beta) act as a neuroprotective agent in cerebral ischemia?]. Journal De La Sociã©Tã© De Biologie. 197: 145-50. PMID 12910629  0.814
2003 Maillet M, Robert SJ, Cacquevel M, Gastineau M, Vivien D, Bertoglio J, Zugaza JL, Fischmeister R, Lezoualc'h F. Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha. Nature Cell Biology. 5: 633-9. PMID 12819788 DOI: 10.1038/ncb1007  0.305
2003 Lesné S, Docagne F, Gabriel C, Liot G, Lahiri DK, Buée L, Plawinski L, Delacourte A, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice. The Journal of Biological Chemistry. 278: 18408-18. PMID 12626500 DOI: 10.1074/Jbc.M300819200  0.685
2003 Valable S, Bellail A, Lesné S, Liot G, Mackenzie ET, Vivien D, Bernaudin M, Petit E. Angiopoietin-1-induced PI3-kinase activation prevents neuronal apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 443-5. PMID 12514118 DOI: 10.1096/Fj.02-0372Fje  0.385
2003 Gabriel C, Ali C, Lesné S, Fernández-Monreal M, Docagne F, Plawinski L, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 277-9. PMID 12490542 DOI: 10.1096/Fj.02-0403Fje  0.811
2003 Docagne F, Ali C, Lesne S, Nicole O, MacKenzie ET, Buisson A, Vivien D. Le tranforming growth factor-β (TGF-p) a t-il un rôle neuroprotecteur dans l’ischémie cérébrale ? Journal De La SociéTé De Biologie. 197: 145-150. DOI: 10.1051/Jbio/2003197020145  0.758
2003 Vivien D, Fernández-Monreal M, Nicole O, Buisson A. Erratum: Reply to “Tissue plasminogen activator and NMDA receptor cleavage” Nature Medicine. 9: 975-975. DOI: 10.1038/NM0703-975B  0.698
2003 Vivien D, Monréal MF, Nicole O, Buisson A. Reply to "Tissue plasminogen activator and NMDA receptor cleavage" Nature Medicine. 9: 372-373. DOI: 10.1038/nm0403-372  0.69
2002 Docagne F, Nicole O, Gabriel C, Fernández-Monreal M, Lesné S, Ali C, Plawinski L, Carmeliet P, MacKenzie ET, Buisson A, Vivien D. Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis. Molecular and Cellular Neurosciences. 21: 634-44. PMID 12504596 DOI: 10.1006/Mcne.2002.1206  0.828
2002 Chuquet J, Benchenane K, Liot G, Fernández-Monreal M, Toutain J, Blanchet S, Eveno E, Auffray C, Piétu G, Buisson A, Touzani O, MacKenzie ET, Vivien D. Matching gene expression with hypometabolism after cerebral ischemia in the nonhuman primate. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1165-9. PMID 12368653 DOI: 10.1097/00004647-200210000-00002  0.772
2002 Lesné S, Blanchet S, Docagne F, Liot G, Plawinski L, MacKenzie ET, Auffray C, Buisson A, Piétu G, Vivien D. Transforming growth factor-beta1-modulated cerebral gene expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1114-23. PMID 12218417 DOI: 10.1097/00004647-200209000-00009  0.706
2001 Docagne F, Colloc'h N, Bougueret V, Page M, Paput J, Tripier M, Dutartre P, MacKenzie ET, Buisson A, Komesli S, Vivien D. A soluble transforming growth factor-beta (TGF-beta ) type I receptor mimics TGF-beta responses. The Journal of Biological Chemistry. 276: 46243-50. PMID 11544249 DOI: 10.1074/jbc.M010915200  0.68
2001 Ali C, Docagne F, Nicole O, Lesné S, Toutain J, Young A, Chazalviel L, Divoux D, Caly M, Cabal P, Derlon JM, MacKenzie ET, Buisson A, Vivien D. Increased expression of transforming growth factor-beta after cerebral ischemia in the baboon: an endogenous marker of neuronal stress? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 820-7. PMID 11435794 DOI: 10.1097/00004647-200107000-00007  0.725
2001 Nicole O, Ali C, Docagne F, Plawinski L, MacKenzie ET, Vivien D, Buisson A. Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3024-33. PMID 11312287 DOI: 10.1523/Jneurosci.21-09-03024.2001  0.74
2001 Nicole O, Docagne F, Ali C, Margaill I, Carmeliet P, MacKenzie ET, Vivien D, Buisson A. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nature Medicine. 7: 59-64. PMID 11135617 DOI: 10.1038/83358  0.739
2000 Ali C, Nicole O, Docagne F, Lesne S, MacKenzie ET, Nouvelot A, Buisson A, Vivien D. Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitotoxicity in the brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 956-66. PMID 10894179 DOI: 10.1097/00004647-200006000-00008  0.793
2000 Vivien D, Buisson A. Serine protease inhibitors: novel therapeutic targets for stroke? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 755-64. PMID 10826525 DOI: 10.1097/00004647-200005000-00001  0.752
2000 Bernaudin M, Bellail A, Marti HH, Yvon A, Vivien D, Duchatelle I, Mackenzie ET, Petit E. Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain. Glia. 30: 271-8. PMID 10756076 DOI: 10.1002/(SICI)1098-1136(200005)30:3<271::AID-GLIA6>3.0.CO;2-H  0.388
1999 Ruocco A, Nicole O, Docagne F, Ali C, Chazalviel L, Komesli S, Yablonsky F, Roussel S, MacKenzie ET, Vivien D, Buisson A. A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1345-53. PMID 10598939 DOI: 10.1097/00004647-199912000-00008  0.707
1999 Docagne F, Nicole O, Marti HH, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1315-24. PMID 10428756 DOI: 10.1096/fasebj.13.11.1315  0.734
1998 Buisson A, Nicole O, Docagne F, Sartelet H, Mackenzie ET, Vivien D. Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1683-91. PMID 9837858 DOI: 10.1096/Fasebj.12.15.1683  0.734
1998 Komesli S, Vivien D, Dutartre P. Chimeric extracellular domain type II transforming growth factor (TGF)-beta receptor fused to the Fc region of human immunoglobulin as a TGF-beta antagonist. European Journal of Biochemistry / Febs. 254: 505-13. PMID 9688260 DOI: 10.1046/J.1432-1327.1998.2540505.X  0.323
1998 Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. The Embo Journal. 17: 3091-100. PMID 9606191 DOI: 10.1093/emboj/17.11.3091  0.315
1998 Vivien D, Bernaudin M, Buisson A, Divoux D, MacKenzie ET, Nouvelot A. Evidence of type I and type II transforming growth factor-beta receptors in central nervous tissues: changes induced by focal cerebral ischemia. Journal of Neurochemistry. 70: 2296-304. PMID 9603194 DOI: 10.1046/J.1471-4159.1998.70062296.X  0.714
1995 Vivien D, Attisano L, Wrana JL, Massagué J. Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes. The Journal of Biological Chemistry. 270: 7134-41. PMID 7706250 DOI: 10.1074/Jbc.270.13.7134  0.68
1995 Vivien D, Wrana JL. Ligand-induced recruitment and phosphorylation of reduced TGF-beta type I receptor. Experimental Cell Research. 221: 60-5. PMID 7589256 DOI: 10.1006/excr.1995.1352  0.528
1994 Vivien D, Bogdanowicz P, Boumediene K, Martiny L, Haye B, Pujol JP. Different phosphorylated forms of inositolphosphate glycan could be involved in the transforming growth factor-beta 1 (TGF-beta 1) signalling pathway. Cellular Signalling. 6: 173-80. PMID 8086280 DOI: 10.1016/0898-6568(94)90074-4  0.309
1993 Vivien D, Petitfrère E, Martiny L, Sartelet H, Galéra P, Haye B, Pujol JP. IPG (inositolphosphate glycan) as a cellular signal for TGF-beta 1 modulation of chondrocyte cell cycle. Journal of Cellular Physiology. 155: 437-44. PMID 8388000 DOI: 10.1002/Jcp.1041550302  0.314
1992 Vivien D, Galéra P, Lebrun E, Daireaux M, Loyau G, Pujol JP. TGF-beta-induced G2/M delay in proliferating rabbit articular chondrocytes is associated with an enhancement of replication rate and a cAMP decrease: possible involvement of pertussis toxin-sensitive pathway. Journal of Cellular Physiology. 150: 291-8. PMID 1346400 DOI: 10.1002/jcp.1041500211  0.304
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