| Year |
Citation |
Score |
| 2021 |
Pappolla MA, Perry G, Fang X, Zagorski M, Sambamurti K, Poeggeler B. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Neurobiology of Disease. 105403. PMID 34087380 DOI: 10.1016/j.nbd.2021.105403 |
0.67 |
|
| 2018 |
Pappolla MA, Matsubara E, Vidal R, Pacheco-Quinto J, Poeggeler B, Zagorski M, Sambamurti K. Melatonin treatment enhances Aβ lymphatic clearance in a transgenic mouse model of amyloidosis. Current Alzheimer Research. PMID 29637859 DOI: 10.2174/1567205015666180411092551 |
0.674 |
|
| 2015 |
Baranello RJ, Bharani KL, Padmaraju V, Chopra N, Lahiri DK, Greig NH, Pappolla MA, Sambamurti K. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. Current Alzheimer Research. 12: 32-46. PMID 25523424 DOI: 10.2174/1567205012666141218140953 |
0.694 |
|
| 2014 |
Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E. Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice. Neurobiology of Disease. 71: 215-9. PMID 25102344 DOI: 10.1016/J.Nbd.2014.07.012 |
0.64 |
|
| 2014 |
Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K. Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein. Plos One. 9: e91531. PMID 24658363 DOI: 10.1371/Journal.Pone.0091531 |
0.636 |
|
| 2014 |
Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E. Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice Neurobiology of Disease. 71: 215-219. DOI: 10.1016/j.nbd.2014.07.012 |
0.612 |
|
| 2013 |
Pinnix I, Ghiso JA, Pappolla MA, Sambamurti K. Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 474-83. PMID 23570890 DOI: 10.1016/J.Jagp.2013.02.009 |
0.643 |
|
| 2011 |
Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA. Targets for AD treatment: conflicting messages from γ-secretase inhibitors. Journal of Neurochemistry. 117: 359-74. PMID 21320126 DOI: 10.1111/J.1471-4159.2011.07213.X |
0.682 |
|
| 2010 |
Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. Plos One. 5: e10206. PMID 20421998 DOI: 10.1371/Journal.Pone.0010206 |
0.691 |
|
| 2010 |
Prakasam A, Muthuswamy A, Ablonczy Z, Greig NH, Fauq A, Rao KJ, Pappolla MA, Sambamurti K. Differential accumulation of secreted AbetaPP metabolites in ocular fluids. Journal of Alzheimer's Disease : Jad. 20: 1243-53. PMID 20413851 DOI: 10.3233/Jad-2010-100210 |
0.669 |
|
| 2010 |
Zambón D, Quintana M, Mata P, Alonso R, Benavent J, Cruz-Sánchez F, Gich J, Pocovà M, Civeira F, Capurro S, Bachman D, Sambamurti K, Nicholas J, Pappolla MA. Higher incidence of mild cognitive impairment in familial hypercholesterolemia. The American Journal of Medicine. 123: 267-74. PMID 20193836 DOI: 10.1016/J.Amjmed.2009.08.015 |
0.565 |
|
| 2009 |
Sambamurti K, Jagannatha Rao KS, Pappolla MA. Frontiers in the pathogenesis of Alzheimer's disease. Indian Journal of Psychiatry. 51: S56-60. PMID 21416019 |
0.639 |
|
| 2009 |
Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radical Research. 43: 156-64. PMID 19160110 DOI: 10.1080/10715760802644694 |
0.738 |
|
| 2008 |
Venugopal C, Demos CM, Rao KS, Pappolla MA, Sambamurti K. Beta-secretase: structure, function, and evolution. Cns & Neurological Disorders Drug Targets. 7: 278-94. PMID 18673212 DOI: 10.2174/187152708784936626 |
0.676 |
|
| 2008 |
Sambamurti K, Pappolla MA, Jagannatha Rao KS. Value in development of a TAPIR-like mouse monoclonal antibody to Abeta. Journal of Alzheimer's Disease : Jad. 14: 175-7. PMID 18663823 DOI: 10.3233/Jad-2008-14205 |
0.691 |
|
| 2008 |
Sambamurti K, Prakasam A, Jayachandran AD, Venugopal C, Rao JK, Lahiri DK, Greig NH, Pappolla MA, Zhou Y. P1-412: Isoprenoids phenocopy familial Alzheimer's disease mutations and regulate gamma-secretase Alzheimer's & Dementia. 4: T340-T340. DOI: 10.1016/J.Jalz.2008.05.994 |
0.61 |
|
| 2008 |
Pappolla MA, Ros E, Sambamurti K, Pocovi M, Nicholas J, Mata P, Alonso R, Bachman D, Cruz-Sanchez F, Benavent J, Capurro S, Zambon D. O1-01-08: Cognitive impairment in heterozygous familial hypercholesterolemia Alzheimer's & Dementia. 4: T108-T108. DOI: 10.1016/J.Jalz.2008.05.218 |
0.54 |
|
| 2008 |
Pacheco-Quinto J, Sambamurti K, Pappolla MA. P3-343: Homocysteine inhibits the enzymatic degradation of Aβ peptide Alzheimer's & Dementia. 4: T622-T622. DOI: 10.1016/J.Jalz.2008.05.1912 |
0.607 |
|
| 2007 |
Venugopal C, Pappolla MA, Sambamurti K. Insulysin cleaves the APP cytoplasmic fragment at multiple sites. Neurochemical Research. 32: 2225-34. PMID 17701350 DOI: 10.1007/S11064-007-9449-Z |
0.671 |
|
| 2006 |
Pacheco-Quinto J, Rodriguez de Turco EB, DeRosa S, Howard A, Cruz-Sanchez F, Sambamurti K, Refolo L, Petanceska S, Pappolla MA. Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels. Neurobiology of Disease. 22: 651-6. PMID 16516482 DOI: 10.1016/J.Nbd.2006.01.005 |
0.687 |
|
| 2006 |
Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA. Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochimica Et Biophysica Acta. 1762: 447-52. PMID 16503402 DOI: 10.1016/J.Bbadis.2006.01.008 |
0.743 |
|
| 2005 |
Poeggeler B, Durand G, Polidori A, Pappolla MA, Vega-Naredo I, Coto-Montes A, Böker J, Hardeland R, Pucci B. Mitochondrial medicine: neuroprotection and life extension by the new amphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent. Journal of Neurochemistry. 95: 962-73. PMID 16135084 DOI: 10.1111/j.1471-4159.2005.03425.x |
0.37 |
|
| 2005 |
Lukiw WJ, Pappolla M, Pelaez RP, Bazan NG. Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism. Cellular and Molecular Neurobiology. 25: 475-83. PMID 16075376 DOI: 10.1007/S10571-005-4010-6 |
0.382 |
|
| 2003 |
Marlow L, Cain M, Pappolla MA, Sambamurti K. Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP). Journal of Molecular Neuroscience : Mn. 20: 233-9. PMID 14501002 DOI: 10.1385/Jmn:20:3:233 |
0.674 |
|
| 2003 |
Wadghiri YZ, Sigurdsson EM, Sadowski M, Elliott JI, Li Y, Scholtzova H, Tang CY, Aguinaldo G, Pappolla M, Duff K, Wisniewski T, Turnbull DH. Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 50: 293-302. PMID 12876705 DOI: 10.1002/Mrm.10529 |
0.456 |
|
| 2003 |
Pappolla MA, Bryant-Thomas TK, Herbert D, Pacheco J, Fabra Garcia M, Manjon M, Girones X, Henry TL, Matsubara E, Zambon D, Wolozin B, Sano M, Cruz-Sanchez FF, Thal LJ, Petanceska SS, et al. Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology. Neurology. 61: 199-205. PMID 12874399 DOI: 10.1212/01.Wnl.0000070182.02537.84 |
0.459 |
|
| 2003 |
Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, Herbert D, Cruz-Sanchez F, Chyan YJ, Smith MA, Perry G, Shoji M, Abe K, Leone A, Grundke-Ikbal I, Wilson GL, ... ... Pappolla MA, et al. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. Journal of Neurochemistry. 85: 1101-8. PMID 12753069 DOI: 10.1046/J.1471-4159.2003.01654.X |
0.706 |
|
| 2002 |
Bozner P, Wilson GL, Druzhyna NM, Bryant-Thomas TK, LeDoux SP, Wilson GL, Pappolla MA. Deficiency of chaperonin 60 in Down's syndrome. Journal of Alzheimer's Disease : Jad. 4: 479-86. PMID 12515899 DOI: 10.3233/Jad-2002-4604 |
0.374 |
|
| 2002 |
Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radical Biology & Medicine. 33: 173-81. PMID 12106813 DOI: 10.1016/S0891-5849(02)00841-9 |
0.681 |
|
| 2002 |
Pappolla MA, Simovich MJ, Bryant-Thomas T, Chyan YJ, Poeggeler B, Dubocovich M, Bick R, Perry G, Cruz-Sanchez F, Smith MA. The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors. Journal of Pineal Research. 32: 135-42. PMID 12074096 DOI: 10.1034/J.1600-079X.2002.1O838.X |
0.662 |
|
| 2001 |
Poeggeler B, Miravalle L, Zagorski MG, Wisniewski T, Chyan YJ, Zhang Y, Shao H, Bryant-Thomas T, Vidal R, Frangione B, Ghiso J, Pappolla MA. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry. 40: 14995-5001. PMID 11732920 DOI: 10.1021/Bi0114269 |
0.641 |
|
| 2001 |
Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". Journal of Neurochemistry. 78: 121-8. PMID 11432979 DOI: 10.1046/J.1471-4159.2001.00379.X |
0.697 |
|
| 2000 |
Nunomura A, Perry G, Pappolla MA, Friedland RP, Hirai K, Chiba S, Smith MA. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. Journal of Neuropathology and Experimental Neurology. 59: 1011-7. PMID 11089579 DOI: 10.1093/Jnen/59.11.1011 |
0.771 |
|
| 2000 |
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiology of Disease. 7: 321-31. PMID 10964604 DOI: 10.1006/Nbdi.2000.0304 |
0.682 |
|
| 2000 |
Pappolla MA, Chyan YJ, Poeggeler B, Frangione B, Wilson G, Ghiso J, Reiter RJ. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 203-31. PMID 10847561 DOI: 10.1007/S007020050018 |
0.595 |
|
| 1999 |
Omar RA, Chyan YJ, Andorn AC, Poeggeler B, Robakis NK, Pappolla MA. Increased Expression but Reduced Activity of Antioxidant Enzymes in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 1: 139-145. PMID 12213999 DOI: 10.3233/Jad-1999-1301 |
0.537 |
|
| 1999 |
Pappolla MA, Chyan YJ, Poeggeler B, Bozner P, Ghiso J, LeDoux SP, Wilson GL. Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin. Journal of Pineal Research. 27: 226-9. PMID 10551770 DOI: 10.1111/J.1600-079X.1999.Tb00619.X |
0.497 |
|
| 1999 |
Chyan YJ, Poeggeler B, Omar RA, Chain DG, Frangione B, Ghiso J, Pappolla MA. Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid. The Journal of Biological Chemistry. 274: 21937-42. PMID 10419516 DOI: 10.1074/Jbc.274.31.21937 |
0.617 |
|
| 1999 |
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1959-64. PMID 10066249 |
0.722 |
|
| 1999 |
Poeggeler B, Pappolla MA, Hardeland R, Rassoulpour A, Hodgkins PS, Guidetti P, Schwarcz R. Indole-3-propionate: a potent hydroxyl radical scavenger in rat brain. Brain Research. 815: 382-8. PMID 9878843 DOI: 10.1016/S0006-8993(98)01027-0 |
0.309 |
|
| 1999 |
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease The Journal of Neuroscience. 19: 1959-1964. DOI: 10.1523/JNEUROSCI.19-06-01959.1999 |
0.708 |
|
| 1999 |
Pappolla MA, Chvan Y, Bozner P, Poeggeler B, Frangione B, Hsiao K, Omai RA, Perry G, Smith MA, Ghiso J. INDUCTION OF NAPH CYTOCHROME P450 REDUCTASE BY AMYLOID β PROTEIN Journal of Neuropathology and Experimental Neurology. 58: 531. DOI: 10.1097/00005072-199905000-00099 |
0.332 |
|
| 1998 |
Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PL, Siedlak SL, Tabaton M, Perry G. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. Journal of Neurochemistry. 70: 2212-5. PMID 9572310 DOI: 10.1046/J.1471-4159.1998.70052212.X |
0.779 |
|
| 1998 |
Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA, Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. The American Journal of Pathology. 152: 871-7. PMID 9546346 |
0.588 |
|
| 1998 |
Pappolla M, Bozner P, Soto C, Shao H, Robakis NK, Zagorski M, Frangione B, Ghiso J. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. The Journal of Biological Chemistry. 273: 7185-8. PMID 9516407 DOI: 10.1074/Jbc.273.13.7185 |
0.73 |
|
| 1997 |
Bozner P, Grishko V, LeDoux SP, Wilson GL, Chyan YC, Pappolla MA. The amyloid beta protein induces oxidative damage of mitochondrial DNA. Journal of Neuropathology and Experimental Neurology. 56: 1356-62. PMID 9413284 DOI: 10.1097/00005072-199712000-00010 |
0.425 |
|
| 1997 |
Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DL, Reiter RJ, Efthimiopoulos S, Robakis NK. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1683-90. PMID 9030627 DOI: 10.1523/Jneurosci.17-05-01683.1997 |
0.701 |
|
| 1997 |
Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DLM, Reiter RJ, Efthimiopoulos S, Robakis NK. Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide The Journal of Neuroscience. 17: 1683-1690. DOI: 10.1523/JNEUROSCI.17-05-01683.1997 |
0.584 |
|
| 1997 |
Pappolla MA, Solo C, Bozner P, Franuione B, Ghiso J. MELATONIN PREVENTS FORMATION OF β-SHEETS AND FIBRILS OF P-AMYLOID. A NEW THERAPY FOR AD? Journal of Neuropathology and Experimental Neurology. 56: 575. DOI: 10.1097/00005072-199705000-00028 |
0.384 |
|
| 1997 |
Bozner L, Wilson G, Ledoux S, Chvan J, Pappolla MA. OXIDATIVE DAMAGE OF MITOCHODRIAL DNA IN PC 12 CELLS FOLLOWING EXPOSURE TO AN AMYLOID (3-PROTEIN Journal of Neuropathology and Experimental Neurology. 56: 574. DOI: 10.1097/00005072-199705000-00027 |
0.357 |
|
| 1996 |
Pappolla MA, Sos M, Omar RA, Sambamurti K. The heat shock/oxidative stress connection. Relevance to Alzheimer disease. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 28: 21-34. PMID 8871938 DOI: 10.1007/BF02815201 |
0.663 |
|
| 1996 |
Omar R, Smith M, Perry G, Pappolla M. IMUNOHISTOCHEMICAL EVIDENCE OF OXIDATIVE STRESS IN PARKINSONʼS DISEASE (PD) Journal of Neuropathology and Experimental Neurology. 55: 634. DOI: 10.1097/00005072-199605000-00127 |
0.57 |
|
| 1996 |
Pappolla M, Sos M, Reiter R, Sambamurti K, Omar R, Robakis N, Efthimiopoulos S. 589 Melatonin prevents oxidative damage and heat-shock protein induction in cultured cells exposed to the Alzheimer's amyloid beta protein (Aβ) Neurobiology of Aging. 17: S146-S147. DOI: 10.1016/S0197-4580(96)80591-4 |
0.802 |
|
| 1995 |
Pappolla MA, Sambamurti K, Efthimiopoulos S, Refolo L, Omar RA, Robakis NK. Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins. Neuroscience Letters. 192: 105-8. PMID 7675314 DOI: 10.1016/0304-3940(95)11627-9 |
0.78 |
|
| 1995 |
Refolo LM, Sambamurti K, Efthimiopoulos S, Pappolla MA, Robakis NK. Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization. Journal of Neuroscience Research. 40: 694-706. PMID 7602619 DOI: 10.1002/Jnr.490400515 |
0.774 |
|
| 1995 |
Ogburn J, Sambamurti K, Wisniewski T, Franuione B, Dudley A, Pappolla M. COLLOID INCLUSIONS OF PARKINSONʼS DISEASE Journal of Neuropathology and Experimental Neurology. 54: 445. DOI: 10.1097/00005072-199505000-00152 |
0.571 |
|
| 1994 |
Robakis NK, Pappolla MA. Oxygen-free radicals and amyloidosis in Alzheimer's disease: is there a connection? Neurobiology of Aging. 15: 457-9; discussion 47. PMID 7969722 DOI: 10.1016/0197-4580(94)90077-9 |
0.537 |
|
| 1992 |
Sambamurti K, Shioi J, Anderson JP, Pappolla MA, Robakis NK. Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells. Journal of Neuroscience Research. 33: 319-29. PMID 1453494 DOI: 10.1002/jnr.490330216 |
0.725 |
|
| 1992 |
Pappolla MA, Omar RA, Sambamurti K, Anderson JP, Robakis NK. The genesis of the senile plaque. Further evidence in support of its neuronal origin. The American Journal of Pathology. 141: 1151-9. PMID 1443049 |
0.485 |
|
| 1992 |
Pappolla MA, Omar RA, Kim KS, Robakis NK. Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. The American Journal of Pathology. 140: 621-8. PMID 1372157 |
0.485 |
|
| 1992 |
Sambamurti K, Refolo LM, Shioi J, Pappolla MA, Robakis NK. The Alzheimer's amyloid precursor is cleaved intracellularly in the trans-Golgi network or in a post-Golgi compartment. Annals of the New York Academy of Sciences. 674: 118-28. PMID 1283818 DOI: 10.1111/j.1749-6632.1992.tb27481.x |
0.728 |
|
| 1987 |
Pappolla M, Penton R, Weiss HS, Miller CH, Sahenk Z, Autilio-Gambetti L, Gambetti P. Carbon disulfide axonopathy. Another experimental model characterized by acceleration of neurofilament transport and distinct changes of axonal size. Brain Research. 424: 272-80. PMID 2445451 DOI: 10.1016/0006-8993(87)91471-5 |
0.506 |
|
| 1986 |
Pappolla MA, Chou SM. UNILATERAL RHIZOTOMY PREVENTS AXONAL BALLOONING OF MOTONEURONS IN IDPN INTOXICATION Journal of Neuropathology and Experimental Neurology. 45: 352. DOI: 10.1097/00005072-198605000-00113 |
0.485 |
|
| 1984 |
Pappolla M, Monaco S, Weiss H, Miller C, Sahenk Z, Autillo-Gambetti L, Gambetti P. 38 Slow Axonal Transport In Carbon Disulfide (Cs2) Giant Axonopathy Journal of Neuropathology and Experimental Neurology. 43: 305. DOI: 10.1097/00005072-198405000-00047 |
0.506 |
|
| Show low-probability matches. |
