Richard Allen Cone - Publications

Biophysics Johns Hopkins University, Baltimore, MD 
photoreceptors, mucosal antibodies

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Anderson DJ, Politch JA, Cone RA, Zeitlin L, Lai SK, Santangelo PJ, Moench TR, Whaley KJ. Engineering monoclonal antibody-based contraception and multipurpose prevention technologies†. Biology of Reproduction. PMID 32607584 DOI: 10.1093/Biolre/Ioaa096  0.315
2020 Hoang T, Toler E, DeLong K, Mafunda NA, Bloom SM, Zierden HC, Moench TR, Coleman JS, Hanes J, Kwon DS, Lai SK, Cone RA, Ensign LM. The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis. Plos Pathogens. 16: e1008236. PMID 31971984 DOI: 10.1371/Journal.Ppat.1008236  0.302
2018 Ayehunie S, Wang YY, Landry T, Bogojevic S, Cone RA. Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model. Toxicology Reports. 5: 134-140. PMID 29854584 DOI: 10.1016/J.Toxrep.2017.12.011  0.335
2018 Hoang T, Date AA, Ortiz Ortiz J, Young TW, Bensouda S, Xiao P, Marzinke M, Rohan L, Fuchs EJ, Hendrix C, Gumber S, Villinger F, Cone RA, Hanes J, Ensign LM. Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29802984 DOI: 10.1016/J.Ejpb.2018.05.030  0.313
2017 Tachedjian G, Aldunate M, Bradshaw CS, Cone RA. The role of lactic acid production by probiotic Lactobacillus species in vaginal health. Research in Microbiology. PMID 28435139 DOI: 10.1016/j.resmic.2017.04.001  0.338
2017 Hearps AC, Tyssen D, Srbinovski D, Bayigga L, Diaz DJ, Aldunate M, Cone RA, Gugasyan R, Anderson DJ, Tachedjian G. Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition. Mucosal Immunology. PMID 28401934 DOI: 10.1038/mi.2017.27  0.309
2016 Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA. Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus. Plos One. 11: e0158338. PMID 27362256 DOI: 10.1371/Journal.Pone.0158338  0.313
2016 Wessler T, Chen A, McKinley SA, Cone R, Forest G, Lai SK. Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus. Acs Infectious Diseases. 2: 82-92. PMID 26771004 DOI: 10.1021/Acsinfecdis.5B00108  0.327
2015 Nunn KL, Wang YY, Harit D, Humphrys MS, Ma B, Cone R, Ravel J, Lai SK. Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota. Mbio. 6. PMID 26443453 DOI: 10.1128/Mbio.01084-15  0.341
2015 Aldunate M, Srbinovski D, Hearps AC, Latham CF, Ramsland PA, Gugasyan R, Cone RA, Tachedjian G. Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis. Frontiers in Physiology. 6: 164. PMID 26082720 DOI: 10.3389/fphys.2015.00164  0.374
2014 Cone RA. Vaginal microbiota and sexually transmitted infections that may influence transmission of cell-associated HIV. The Journal of Infectious Diseases. 210: S616-21. PMID 25414415 DOI: 10.1093/infdis/jiu459  0.331
2014 Wang YY, Kannan A, Nunn KL, Murphy MA, Subramani DB, Moench T, Cone R, Lai SK. IgG in cervicovaginal mucus traps HSV and prevents vaginal herpes infections. Mucosal Immunology. 7: 1036-44. PMID 24496316 DOI: 10.1038/Mi.2013.120  0.342
2013 Wang YY, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J. The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. Biomacromolecules. 14: 4429-35. PMID 24266646 DOI: 10.1021/Bm401356Q  0.345
2013 O'Hanlon DE, Moench TR, Cone RA. Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota. Plos One. 8: e80074. PMID 24223212 DOI: 10.1371/journal.pone.0080074  0.712
2013 Aldunate M, Tyssen D, Johnson A, Zakir T, Sonza S, Moench T, Cone R, Tachedjian G. Vaginal concentrations of lactic acid potently inactivate HIV. The Journal of Antimicrobial Chemotherapy. 68: 2015-25. PMID 23657804 DOI: 10.1093/jac/dkt156  0.339
2013 Ensign LM, Henning A, Schneider CS, Maisel K, Wang YY, Porosoff MD, Cone R, Hanes J. Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues. Molecular Pharmaceutics. 10: 2176-82. PMID 23617606 DOI: 10.1021/Mp400087Y  0.309
2012 Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Science Translational Medicine. 4: 138ra79. PMID 22700955 DOI: 10.1126/Scitranslmed.3003453  0.304
2012 Moench TR, O'Hanlon DE, Cone RA. Evaluation of microbicide gel adherence monitoring methods. Sexually Transmitted Diseases. 39: 335-40. PMID 22504592 DOI: 10.1097/Olq.0B013E31824790Bb  0.663
2011 O'Hanlon DE, Moench TR, Cone RA. In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide. Bmc Infectious Diseases. 11: 200. PMID 21771337 DOI: 10.1186/1471-2334-11-200  0.701
2010 O'Hanlon DE, Lanier BR, Moench TR, Cone RA. Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli. Bmc Infectious Diseases. 10: 120. PMID 20482854 DOI: 10.1186/1471-2334-10-120  0.679
2009 Lai SK, Hida K, Shukair S, Wang YY, Figueiredo A, Cone R, Hope TJ, Hanes J. Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus. Journal of Virology. 83: 11196-200. PMID 19692470 DOI: 10.1128/Jvi.01899-08  0.371
2009 Mumper RJ, Bell MA, Worthen DR, Cone RA, Lewis GR, Paull JR, Moench TR. Formulating a sulfonated antiviral dendrimer in a vaginal microbicidal gel having dual mechanisms of action. Drug Development and Industrial Pharmacy. 35: 515-24. PMID 19040181 DOI: 10.1080/03639040802488097  0.33
2007 Lai SK, O'Hanlon DE, Harrold S, Man ST, Wang YY, Cone R, Hanes J. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus. Proceedings of the National Academy of Sciences of the United States of America. 104: 1482-7. PMID 17244708 DOI: 10.1073/Pnas.0608611104  0.669
2006 Cone RA, Hoen T, Wong X, Abusuwwa R, Anderson DJ, Moench TR. Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission. Bmc Infectious Diseases. 6: 90. PMID 16740164 DOI: 10.1186/1471-2334-6-90  0.339
2005 Olmsted SS, Khanna KV, Ng EM, Whitten ST, Johnson ON, Markham RB, Cone RA, Moench TR. Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model. Bmc Infectious Diseases. 5: 79. PMID 16194280 DOI: 10.1186/1471-2334-5-79  0.752
2003 Boskey ER, Moench TR, Hees PS, Cone RA. A self-sampling method to obtain large volumes of undiluted cervicovaginal secretions. Sexually Transmitted Diseases. 30: 107-9. PMID 12567165 DOI: 10.1097/00007435-200302000-00002  0.603
2002 Achilles SL, Shete PB, Whaley KJ, Moench TR, Cone RA. Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis. Sexually Transmitted Diseases. 29: 655-64. PMID 12438901 DOI: 10.1097/00007435-200211000-00007  0.643
2002 Castle PE, Karp DA, Zeitlin L, García-Moreno E B, Moench TR, Whaley KJ, Cone RA. Human monoclonal antibody stability and activity at vaginal pH. Journal of Reproductive Immunology. 56: 61-76. PMID 12106884 DOI: 10.1016/S0165-0378(02)00013-X  0.377
2002 Khanna KV, Whaley KJ, Zeitlin L, Moench TR, Mehrazar K, Cone RA, Liao Z, Hildreth JE, Hoen TE, Shultz L, Markham RB. Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent. The Journal of Clinical Investigation. 109: 205-11. PMID 11805132 DOI: 10.1172/JCI13236  0.303
2001 Olmsted SS, Padgett JL, Yudin AI, Whaley KJ, Moench TR, Cone RA. Diffusion of macromolecules and virus-like particles in human cervical mucus. Biophysical Journal. 81: 1930-7. PMID 11566767 DOI: 10.1016/S0006-3495(01)75844-4  0.731
2001 Boskey ER, Cone RA, Whaley KJ, Moench TR. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. Human Reproduction (Oxford, England). 16: 1809-13. PMID 11527880 DOI: 10.1093/Humrep/16.9.1809  0.625
2001 Zeitlin L, Hoen TE, Achilles SL, Hegarty TA, Jerse AE, Kreider JW, Olmsted SS, Whaley KJ, Cone RA, Moench TR. Tests of Buffergel for contraception and prevention of sexually transmitted diseases in animal models. Sexually Transmitted Diseases. 28: 417-23. PMID 11460027 DOI: 10.1097/00007435-200107000-00010  0.741
2000 Olmsted SS, Dubin NH, Cone RA, Moench TR. The rate at which human sperm are immobilized and killed by mild acidity. Fertility and Sterility. 73: 687-93. PMID 10731526 DOI: 10.1016/S0015-0282(99)00640-8  0.749
1999 Boskey ER, Telsch KM, Whaley KJ, Moench TR, Cone RA. Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification. Infection and Immunity. 67: 5170-5. PMID 10496892 DOI: 10.1128/Iai.67.10.5170-5175.1999  0.649
1998 Zeitlin L, Castle PE, Whaley KJ, Moench TR, Cone RA. Comparison of an anti-HSV-2 monoclonal IgG and its IgA switch variant for topical immunoprotection of the mouse vagina. Journal of Reproductive Immunology. 40: 93-101. PMID 9862259 DOI: 10.1016/S0165-0378(98)00041-2  0.306
1998 Zeitlin L, Olmsted SS, Moench TR, Co MS, Martinell BJ, Paradkar VM, Russell DR, Queen C, Cone RA, Whaley KJ. A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes. Nature Biotechnology. 16: 1361-4. PMID 9853620 DOI: 10.1038/4344  0.735
1997 Zeitlin L, Whaley KJ, Hegarty TA, Moench TR, Cone RA. Tests of vaginal microbicides in the mouse genital herpes model. Contraception. 56: 329-35. PMID 9437563 DOI: 10.1016/S0010-7824(97)00154-6  0.346
1997 Castle PE, Whaley KJ, Hoen TE, Moench TR, Cone RA. Contraceptive effect of sperm-agglutinating monoclonal antibodies in rabbits. Biology of Reproduction. 56: 153-9. PMID 9002644 DOI: 10.1095/biolreprod56.1.153  0.31
1997 Olmsted SS, Dubin NH, Cone RA, Moench TR. O-168 How rapidly can vaginal acidity (pH 4) stop sperm? Fertility and Sterility. 68. DOI: 10.1016/S0015-0282(97)90800-1  0.735
1996 Sherwood JK, Zeitlin L, Whaley KJ, Cone RA, Saltzman M. Controlled release of antibodies for long-term topical passive immunoprotection of female mice against genital herpes. Nature Biotechnology. 14: 468-71. PMID 9630921 DOI: 10.1038/nbt0496-468  0.322
1996 Zeitlin L, Whaley KJ, Sanna PP, Moench TR, Bastidas R, De Logu A, Williamson RA, Burton DR, Cone RA. Topically applied human recombinant monoclonal IgG1 antibody and its Fab and F(ab')2 fragments protect mice from vaginal transmission of HSV-2. Virology. 225: 213-5. PMID 8918548 DOI: 10.1006/viro.1996.0589  0.338
1994 Saltzman WM, Radomsky ML, Whaley KJ, Cone RA. Antibody diffusion in human cervical mucus. Biophysical Journal. 66: 508-15. PMID 8161703 DOI: 10.1016/S0006-3495(94)80802-1  0.318
1994 Whaley KJ, Zeitlin L, Barratt RA, Hoen TE, Cone RA. Passive immunization of the vagina protects mice against vaginal transmission of genital herpes infections. The Journal of Infectious Diseases. 169: 647-9. PMID 8158042 DOI: 10.1093/Infdis/169.3.647  0.32
1993 Whaley KJ, Barratt RA, Zeitlin L, Hoen TE, Cone RA. Nonoxynol-9 protects mice against vaginal transmission of genital herpes infections. The Journal of Infectious Diseases. 168: 1009-11. PMID 8397261 DOI: 10.1093/Infdis/168.4.1009  0.305
1993 Moench TR, Whaley KJ, Mandrell TD, Bishop BD, Witt CJ, Cone RA. The cat/feline immunodeficiency virus model for transmucosal transmission of AIDS: nonoxynol-9 contraceptive jelly blocks transmission by an infected cell inoculum. Aids (London, England). 7: 797-802. PMID 8395855 DOI: 10.1097/00002030-199306000-00006  0.332
1986 Cardullo RA, Cone RA. Mechanical immobilization of rat sperm does not change their oxygen consumption rate. Biology of Reproduction. 34: 820-30. PMID 3730479 DOI: 10.1095/Biolreprod34.5.820  0.628
1974 Poo M, Cone RA. Lateral diffusion of rhodopsin in the photoreceptor membrane. Nature. 247: 438-41. PMID 4818543 DOI: 10.1038/247438a0  0.474
1973 Poo MM, Cone RA. Lateral diffusion of phodopsin in Necturus rods. Experimental Eye Research. 17: 503-10. PMID 4782837 DOI: 10.1016/0014-4835(73)90079-1  0.474
1973 Poo M, Cone RA. Lateral diffusion of rhodopsin in the visual receptor membrane. Journal of Supramolecular Structure. 1: 354. PMID 4543718 DOI: 10.1002/jss.400010411  0.477
1967 Ebrey TG, Cone RA. Melanin, a possible pigment for the photostable electrical responses of the eye. Nature. 213: 360-2. PMID 6029517 DOI: 10.1038/213360A0  0.43
1965 Cone RA, Ebrey TG. Functional independence of the two major components of the rod electroretinogram. Nature. 206: 913-5. PMID 5839845 DOI: 10.1038/206913A0  0.424
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