| Year |
Citation |
Score |
| 2023 |
Condello C, Ayers JI, Dalgard CL, Garcia Garcia MM, Rivera BM, Seeley WW, Perl DP, Prusiner SB. Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220984120. PMID 36952379 DOI: 10.1073/pnas.2220984120 |
0.68 |
|
| 2022 |
Condello C, Merz GE, Aoyagi A, DeGrado WF, Prusiner SB. Aβ and Tau Prions Causing Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 2561: 293-337. PMID 36399277 DOI: 10.1007/978-1-0716-2655-9_16 |
0.668 |
|
| 2022 |
Condello C, Maxwell AM, Castillo E, Aoyagi A, Graff C, Ingelsson M, Lannfelt L, Bird TD, Keene CD, Seeley WW, Perl DP, Head E, Prusiner SB. Aβ and tau prions feature in the neuropathogenesis of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2212954119. PMID 36343257 DOI: 10.1073/pnas.2212954119 |
0.663 |
|
| 2022 |
Holec SAM, Lee J, Oehler A, Ooi FK, Mordes DA, Olson SH, Prusiner SB, Woerman AL. Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein. Acta Neuropathologica. PMID 36018376 DOI: 10.1007/s00401-022-02476-7 |
0.748 |
|
| 2022 |
Ayers JI, Lee J, Monteiro O, Woerman AL, Lazar AA, Condello C, Paras NA, Prusiner SB. Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35115402 DOI: 10.1073/pnas.2113489119 |
0.794 |
|
| 2021 |
Carlson GA, Prusiner SB. How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders. International Journal of Molecular Sciences. 22. PMID 34064393 DOI: 10.3390/ijms22094861 |
0.362 |
|
| 2021 |
Lester E, Ooi FK, Bakkar N, Ayers J, Woerman AL, Wheeler J, Bowser R, Carlson GA, Prusiner SB, Parker R. Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components. Neuron. PMID 33848474 DOI: 10.1016/j.neuron.2021.03.026 |
0.707 |
|
| 2020 |
Condello C, DeGrado WF, Prusiner SB. Prion biology: implications for Alzheimer's disease therapeutics. The Lancet. Neurology. 19: 802-803. PMID 32949533 DOI: 10.1016/S1474-4422(20)30274-X |
0.703 |
|
| 2020 |
Ayers JI, Paras NA, Prusiner SB. Expanding spectrum of prion diseases. Emerging Topics in Life Sciences. 4: 155-167. PMID 32803268 DOI: 10.1042/ETLS20200037 |
0.32 |
|
| 2020 |
Ayers JI, Prusiner SB. Prion protein - mediator of toxicity in multiple proteinopathies. Nature Reviews. Neurology. PMID 32123368 DOI: 10.1038/s41582-020-0332-8 |
0.424 |
|
| 2020 |
Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, ... ... Prusiner SB, et al. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. Acs Medicinal Chemistry Letters. 11: 127-132. PMID 32071678 DOI: 10.1021/Acsmedchemlett.9B00480 |
0.328 |
|
| 2020 |
Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. Plos Pathogens. 16: e1008222. PMID 32017806 DOI: 10.1371/Journal.Ppat.1008222 |
0.76 |
|
| 2019 |
Krejciova Z, Carlson GA, Giles K, Prusiner SB. Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta Neuropathologica Communications. 7: 81. PMID 31109379 DOI: 10.1186/s40478-019-0703-9 |
0.366 |
|
| 2019 |
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, ... ... Prusiner SB, et al. Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain. Science Translational Medicine. 11. PMID 31043574 DOI: 10.1126/Scitranslmed.Aat8462 |
0.793 |
|
| 2019 |
Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines. Acta Neuropathologica. PMID 30690664 DOI: 10.1007/S00401-019-01959-4 |
0.754 |
|
| 2018 |
Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. A long-lived aβ oligomer resistant to fibrillization. Biopolymers. PMID 29319162 DOI: 10.1002/Bip.23096 |
0.347 |
|
| 2018 |
Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, ... ... Prusiner SB, et al. Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311311 DOI: 10.1073/Pnas.1714966115 |
0.794 |
|
| 2017 |
Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279394 DOI: 10.1073/Pnas.1719369115 |
0.727 |
|
| 2017 |
Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29203673 DOI: 10.1073/Pnas.1717193114 |
0.738 |
|
| 2017 |
Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. A novel vector for transgenesis in the rat CNS. Acta Neuropathologica Communications. 5: 84. PMID 29157304 DOI: 10.1186/S40478-017-0484-Y |
0.68 |
|
| 2017 |
Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. Jama Neurology. PMID 29059326 DOI: 10.1001/Jamaneurol.2017.2822 |
0.753 |
|
| 2017 |
Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB. MSA prions exhibit remarkable stability and resistance to inactivation. Acta Neuropathologica. PMID 28849371 DOI: 10.1007/S00401-017-1762-2 |
0.773 |
|
| 2017 |
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, ... Prusiner SB, et al. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nature Chemistry. 9: 874-881. PMID 28837163 DOI: 10.1038/Nchem.2754 |
0.698 |
|
| 2017 |
Giles K, Woerman AL, Berry DB, Prusiner SB. Bioassays and Inactivation of Prions. Cold Spring Harbor Perspectives in Biology. PMID 28246183 DOI: 10.1101/Cshperspect.A023499 |
0.761 |
|
| 2017 |
Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB. α-Synuclein: Multiple System Atrophy Prions. Cold Spring Harbor Perspectives in Medicine. PMID 28213437 DOI: 10.1101/Cshperspect.A024588 |
0.811 |
|
| 2017 |
Watts JC, Prusiner SB. β-Amyloid Prions and the Pathobiology of Alzheimer's Disease. Cold Spring Harbor Perspectives in Medicine. PMID 28193770 DOI: 10.1101/Cshperspect.A023507 |
0.696 |
|
| 2017 |
Watts JC, Prusiner SB. Experimental Models of Inherited PrP Prion Diseases. Cold Spring Harbor Perspectives in Medicine. PMID 28096244 DOI: 10.1101/Cshperspect.A027151 |
0.723 |
|
| 2017 |
Giles K, Olson SH, Prusiner SB. Developing Therapeutics for PrP Prion Diseases. Cold Spring Harbor Perspectives in Medicine. PMID 28096242 DOI: 10.1101/cshperspect.a023747 |
0.427 |
|
| 2016 |
Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911827 DOI: 10.1073/Pnas.1616344113 |
0.728 |
|
| 2016 |
Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. Guinea pig prion protein supports rapid propagation of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease prions. Journal of Virology. PMID 27440899 DOI: 10.1128/Jvi.01106-16 |
0.729 |
|
| 2016 |
Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stoehr J, Hong M. Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. Journal of the American Chemical Society. PMID 27414264 DOI: 10.1021/Jacs.6B03715 |
0.356 |
|
| 2016 |
Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M. FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice. Proceedings of the National Academy of Sciences of the United States of America. 113: 8514-9. PMID 27402759 DOI: 10.1073/Pnas.1607079113 |
0.316 |
|
| 2016 |
Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathologica. PMID 27350609 DOI: 10.1007/S00401-016-1585-6 |
0.822 |
|
| 2016 |
Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Optimization of aryl amides that extend survival in prion-infected mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27317802 DOI: 10.1124/Jpet.116.235556 |
0.724 |
|
| 2016 |
Krejciova Z, Alibhai J, Zhao C, Krencik R, Rzechorzek NM, Ullian EM, Manson J, Ironside J, Giles K, Chandran S, Prusiner SB, Head M. Creutzfeldt-Jakob disease prion propagation in human iPS cells-derived astrocytes Prion. 10. PMID 27088809 DOI: 10.1080/19336896.2016.1163103 |
0.361 |
|
| 2015 |
Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, et al. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 112: E5308-17. PMID 26324905 DOI: 10.1073/Pnas.1514475112 |
0.814 |
|
| 2015 |
Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophysical Journal. 109: 793-805. PMID 26287631 DOI: 10.1016/J.Bpj.2015.06.065 |
0.44 |
|
| 2015 |
Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, ... ... Prusiner SB, et al. Propagation of prions causing synucleinopathies in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E4949-58. PMID 26286986 DOI: 10.1073/Pnas.1513426112 |
0.828 |
|
| 2015 |
Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. The Journal of Pharmacology and Experimental Therapeutics. 355: 2-12. PMID 26224882 DOI: 10.1124/Jpet.115.224659 |
0.751 |
|
| 2015 |
Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB. Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice. The Journal of Infectious Diseases. 212: S17-25. PMID 26116725 DOI: 10.1093/infdis/jiu656 |
0.411 |
|
| 2015 |
Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Annals of Neurology. 78: 540-53. PMID 26094969 DOI: 10.1002/Ana.24463 |
0.679 |
|
| 2015 |
Giles K, Berry D, Condello C, Bhardwaj S, Oehler A, Gallardo-Godoy A, DeArmond S, Renslo A, Prusiner S. Improving therapeutic efficacy of 2-aminothiazoles in PrP prion disease Prion. 9. PMID 25970046 DOI: 10.1080/19336896.2015.1033248 |
0.71 |
|
| 2015 |
Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G. Structural studies of truncated forms of the prion protein PrP. Biophysical Journal. 108: 1548-54. PMID 25809267 DOI: 10.1016/J.Bpj.2015.01.008 |
0.691 |
|
| 2015 |
Levine DJ, Stöhr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR. Mechanism of scrapie prion precipitation with phosphotungstate anions. Acs Chemical Biology. 10: 1269-77. PMID 25695325 DOI: 10.1021/Cb5006239 |
0.57 |
|
| 2015 |
Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. Correction for Watts et al., Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 112. PMID 25675539 DOI: 10.1073/Pnas.1502028112 |
0.633 |
|
| 2014 |
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 111: 10323-8. PMID 24982139 DOI: 10.1073/Pnas.1408900111 |
0.792 |
|
| 2014 |
Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 10329-34. PMID 24982137 DOI: 10.1073/Pnas.1408968111 |
0.815 |
|
| 2014 |
Watts JC, Prusiner SB. Mouse models for studying the formation and propagation of prions. The Journal of Biological Chemistry. 289: 19841-9. PMID 24860095 DOI: 10.1074/Jbc.R114.550707 |
0.72 |
|
| 2014 |
Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. Evidence that bank vole PrP is a universal acceptor for prions. Plos Pathogens. 10: e1003990. PMID 24699458 DOI: 10.1371/Journal.Ppat.1003990 |
0.714 |
|
| 2014 |
Silber BM, Gever JR, Rao S, Li Z, Renslo AR, Widjaja K, Wong C, Giles K, Freyman Y, Elepano M, Irwin JJ, Jacobson MP, Prusiner SB. Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells. Bioorganic & Medicinal Chemistry. 22: 1960-72. PMID 24530226 DOI: 10.1016/J.Bmc.2014.01.001 |
0.407 |
|
| 2014 |
Watts J, Giles K, Grillo S, Lemus A, DeArmond S, Prusiner S. Erratum: Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease (Proceedings of the National Academy of Sciences of the United States of America (2011) 108 (2528-2533) DOI: 10.1073/pnas. 1019034108) Proceedings of the National Academy of Sciences of the United States of America. 111: 3895. DOI: 10.1073/Pnas.1401579111 |
0.64 |
|
| 2014 |
Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in themouse brain (vol 107, pg 14508, 2010) Proceedings of the National Academy of Sciences of the United States of America. 111: 3645-3645. DOI: 10.1073/Pnas.1401576111 |
0.562 |
|
| 2013 |
Prusiner SB. Biology and genetics of prions causing neurodegeneration. Annual Review of Genetics. 47: 601-23. PMID 24274755 DOI: 10.1146/annurev-genet-110711-155524 |
0.473 |
|
| 2013 |
Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. Transmission of multiple system atrophy prions to transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 19555-60. PMID 24218576 DOI: 10.1073/Pnas.1318268110 |
0.712 |
|
| 2013 |
Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB. Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Bioorganic & Medicinal Chemistry. 21: 7999-8012. PMID 24183589 DOI: 10.1016/J.Bmc.2013.09.022 |
0.578 |
|
| 2013 |
Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. Drug resistance confounding prion therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 110: E4160-9. PMID 24128760 DOI: 10.1073/Pnas.1317164110 |
0.711 |
|
| 2013 |
Li Z, Rao S, Gever JR, Widjaja K, Prusiner SB, Silber BM. Optimization of Arylamides as Novel, Potent and Brain-penetrant Antiprion Lead Compounds. Acs Medicinal Chemistry Letters. 4: 647-650. PMID 23977416 DOI: 10.1021/ml300454k |
0.393 |
|
| 2013 |
Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. 347: 325-38. PMID 23965382 DOI: 10.1124/Jpet.113.205799 |
0.377 |
|
| 2013 |
Dehdashti SJ, Zheng W, Gever JR, Wilhelm R, Nguyen DT, Sittampalam G, McKew JC, Austin CP, Prusiner SB. A high-throughput screening assay for determining cellular levels of total tau protein. Current Alzheimer Research. 10: 679-87. PMID 23905996 DOI: 10.2174/15672050113109990143 |
0.354 |
|
| 2013 |
Li Z, Gever J, Rao S, Widjaja K, Prusiner SB, Silber BM. Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds. Acs Medicinal Chemistry Letters. 4: 397-401. PMID 23847718 DOI: 10.1021/ml300472n |
0.395 |
|
| 2013 |
Li Z, Silber BM, Rao S, Gever JR, Bryant C, Gallardo-Godoy A, Dolghih E, Widjaja K, Elepano M, Jacobson MP, Prusiner SB, Renslo AR. 2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease. Chemmedchem. 8: 847-57. PMID 23509039 DOI: 10.1002/Cmdc.201300007 |
0.362 |
|
| 2013 |
Godsave SF, Wille H, Pierson J, Prusiner SB, Peters PJ. Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo. Neurobiology of Aging. 34: 1621-31. PMID 23481568 DOI: 10.1016/j.neurobiolaging.2012.12.015 |
0.408 |
|
| 2013 |
Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. Convergent replication of mouse synthetic prion strains. The American Journal of Pathology. 182: 866-74. PMID 23438476 DOI: 10.1016/J.Ajpath.2012.11.038 |
0.675 |
|
| 2013 |
Silber BM, Rao S, Fife KL, Gallardo-Godoy A, Renslo AR, Dalvie DK, Giles K, Freyman Y, Elepano M, Gever JR, Li Z, Jacobson MP, Huang Y, Benet LZ, Prusiner SB. Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharmaceutical Research. 30: 932-50. PMID 23417511 DOI: 10.1007/S11095-012-0912-4 |
0.345 |
|
| 2013 |
Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. Chimeric elk/mouse prion proteins in transgenic mice. The Journal of General Virology. 94: 443-52. PMID 23100369 DOI: 10.1099/vir.0.045989-0 |
0.451 |
|
| 2013 |
Stoehr J, Watts J, Oehler A, DeArmond S, Giles K, Prusiner SB. P1-043: Synthetic beta-amyloid prions Alzheimer's & Dementia. 9: P168-P168. DOI: 10.1016/J.Jalz.2013.05.263 |
0.616 |
|
| 2012 |
Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Molecular Therapy. Nucleic Acids. 1: e9. PMID 23344724 DOI: 10.1038/Mtna.2011.6 |
0.683 |
|
| 2012 |
Stanker LH, Scotcher MC, Lin A, McGarvey J, Prusiner SB, Hnasko R. Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions. Hybridoma (2005). 31: 314-24. PMID 23098297 DOI: 10.1089/hyb.2012.0022 |
0.434 |
|
| 2012 |
Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. Plos One. 7: e39112. PMID 22768295 DOI: 10.1371/Journal.Pone.0039112 |
0.605 |
|
| 2012 |
Prusiner SB. Cell biology. A unifying role for prions in neurodegenerative diseases. Science (New York, N.Y.). 336: 1511-3. PMID 22723400 DOI: 10.1126/science.1222951 |
0.376 |
|
| 2012 |
Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proceedings of the National Academy of Sciences of the United States of America. 109: 11025-30. PMID 22711819 DOI: 10.1073/Pnas.1206555109 |
0.694 |
|
| 2012 |
Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G. Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold. Biophysical Journal. 102: 2339-44. PMID 22677387 DOI: 10.1016/j.bpj.2012.04.011 |
0.372 |
|
| 2012 |
Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB. Salivary prions in sheep and deer. Prion. 6: 52-61. PMID 22453179 DOI: 10.4161/Pri.6.1.16984 |
0.449 |
|
| 2012 |
Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL. Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling. Analytical Chemistry. 84: 4014-21. PMID 22444387 DOI: 10.1021/Ac203330Z |
0.588 |
|
| 2012 |
Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. Identification of I137M and other mutations that modulate incubation periods for two human prion strains. Journal of Virology. 86: 6033-41. PMID 22438549 DOI: 10.1128/Jvi.07027-11 |
0.458 |
|
| 2012 |
Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 3498-503. PMID 22331873 DOI: 10.1073/Pnas.1121556109 |
0.72 |
|
| 2012 |
Stoehr J, Watts J, Mensinger Z, Oehler A, Grillo S, DeArmond S, Prusiner S, Giles K. O3-04-01: Brain-derived and synthetic Aβ aggregates are prions Alzheimer's & Dementia. 8: P434-P434. DOI: 10.1016/J.Jalz.2012.05.1158 |
0.649 |
|
| 2011 |
Kujala P, Raymond CR, Romeijn M, Godsave SF, van Kasteren SI, Wille H, Prusiner SB, Mabbott NA, Peters PJ. Prion uptake in the gut: identification of the first uptake and replication sites. Plos Pathogens. 7: e1002449. PMID 22216002 DOI: 10.1371/journal.ppat.1002449 |
0.388 |
|
| 2011 |
Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. Protease-resistant prions selectively decrease Shadoo protein. Plos Pathogens. 7: e1002382. PMID 22163178 DOI: 10.1371/Journal.Ppat.1002382 |
0.732 |
|
| 2011 |
Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. Spontaneous generation of anchorless prions in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 21223-8. PMID 22160704 DOI: 10.1073/Pnas.1117827108 |
0.737 |
|
| 2011 |
Colby DW, Prusiner SB. De novo generation of prion strains. Nature Reviews. Microbiology. 9: 771-7. PMID 21947062 DOI: 10.1038/nrmicro2650 |
0.453 |
|
| 2011 |
Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL. A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Molecular & Cellular Proteomics : McP. 10: M111.010728. PMID 21937731 DOI: 10.1074/Mcp.M111.010728 |
0.596 |
|
| 2011 |
Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. Conformational transformation and selection of synthetic prion strains. Journal of Molecular Biology. 413: 527-42. PMID 21839745 DOI: 10.1016/J.Jmb.2011.07.021 |
0.75 |
|
| 2011 |
Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. Conserved properties of human and bovine prion strains on transmission to guinea pigs. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1326-36. PMID 21727894 DOI: 10.1038/Labinvest.2011.89 |
0.397 |
|
| 2011 |
Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S. A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets. The Journal of Biological Chemistry. 286: 27718-28. PMID 21610081 DOI: 10.1074/Jbc.M111.234393 |
0.646 |
|
| 2011 |
Colby DW, Prusiner SB. Prions. Cold Spring Harbor Perspectives in Biology. 3: a006833. PMID 21421910 DOI: 10.1101/cshperspect.a006833 |
0.35 |
|
| 2011 |
Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 2528-33. PMID 21262831 DOI: 10.1073/Pnas.1019034108 |
0.697 |
|
| 2011 |
Gallardo-Godoy A, Gever J, Fife KL, Silber BM, Prusiner SB, Renslo AR. 2-Aminothiazoles as therapeutic leads for prion diseases. Journal of Medicinal Chemistry. 54: 1010-21. PMID 21247166 DOI: 10.1021/Jm101250Y |
0.375 |
|
| 2010 |
Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. Analysis of proteome dynamics in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 14508-13. PMID 20699386 DOI: 10.1073/Pnas.1006551107 |
0.628 |
|
| 2010 |
Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. Human prion strain selection in transgenic mice. Annals of Neurology. 68: 151-61. PMID 20695008 DOI: 10.1002/Ana.22104 |
0.421 |
|
| 2010 |
Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH. Generation of antisera to purified prions in lipid rafts. Prion. 4: 94-104. PMID 20647769 DOI: 10.4161/pri.4.2.12622 |
0.491 |
|
| 2010 |
Stanker LH, Serban AV, Cleveland E, Hnasko R, Lemus A, Safar J, DeArmond SJ, Prusiner SB. Conformation-dependent high-affinity monoclonal antibodies to prion proteins. Journal of Immunology (Baltimore, Md. : 1950). 185: 729-37. PMID 20530267 DOI: 10.4049/jimmunol.0902930 |
0.41 |
|
| 2010 |
Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, Lemus A, Cohen FE, DeArmond SJ, Prusiner SB. Protease-sensitive synthetic prions. Plos Pathogens. 6: e1000736. PMID 20107515 DOI: 10.1371/Journal.Ppat.1000736 |
0.745 |
|
| 2010 |
Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. Discovery of 2-aminothiazoles as potent antiprion compounds. Journal of Virology. 84: 3408-12. PMID 20032192 DOI: 10.1128/Jvi.02145-09 |
0.633 |
|
| 2010 |
Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB. Chemical induction of misfolded prion protein conformers in cell culture. The Journal of Biological Chemistry. 285: 10415-23. PMID 19955177 DOI: 10.1074/Jbc.M109.045112 |
0.666 |
|
| 2010 |
Stoehr J, Colby D, Giles K, Prusiner SB, Wille H. Structural Characterization of Amyloids Comprised of Anchorless Prion Proteins Biophysical Journal. 98: 458a. DOI: 10.1016/J.BPJ.2009.12.2488 |
0.514 |
|
| 2010 |
Wille H, Bian W, McDonald MD, Kendall AK, Colby D, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G. X-Ray Fiber Diffraction Reveals Major Structural Differences Between Brain-Derived Prions and Recombinant Prion Protein Amyloid Biophysical Journal. 98: 457a. DOI: 10.1016/J.BPJ.2009.12.2482 |
0.565 |
|
| 2009 |
Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. Continuous quinacrine treatment results in the formation of drug-resistant prions. Plos Pathogens. 5: e1000673. PMID 19956709 DOI: 10.1371/Journal.Ppat.1000673 |
0.653 |
|
| 2009 |
Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB. Design and construction of diverse mammalian prion strains. Proceedings of the National Academy of Sciences of the United States of America. 106: 20417-22. PMID 19915150 DOI: 10.1073/Pnas.0910350106 |
0.661 |
|
| 2009 |
Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G. Natural and synthetic prion structure from X-ray fiber diffraction. Proceedings of the National Academy of Sciences of the United States of America. 106: 16990-5. PMID 19805070 DOI: 10.1073/pnas.0909006106 |
0.572 |
|
| 2009 |
Tamgüney G, Miller MW, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB. Asymptomatic deer excrete infectious prions in faeces. Nature. 461: 529-32. PMID 19741608 DOI: 10.1038/nature08289 |
0.436 |
|
| 2009 |
Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. Measuring prions by bioluminescence imaging. Proceedings of the National Academy of Sciences of the United States of America. 106: 15002-6. PMID 19706444 DOI: 10.1073/pnas.0907339106 |
0.455 |
|
| 2009 |
Bae SH, Legname G, Serban A, Prusiner SB, Wright PE, Dyson HJ. Prion proteins with pathogenic and protective mutations show similar structure and dynamics. Biochemistry. 48: 8120-8. PMID 19618915 DOI: 10.1021/Bi900923B |
0.409 |
|
| 2009 |
Choi EM, Geschwind MD, Deering C, Pomeroy K, Kuo A, Miller BL, Safar JG, Prusiner SB. Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 624-35. PMID 19434060 DOI: 10.1038/Labinvest.2009.30 |
0.328 |
|
| 2009 |
Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB. Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein. The Journal of General Virology. 90: 1035-47. PMID 19264659 DOI: 10.1099/vir.0.007500-0 |
0.463 |
|
| 2009 |
Wille H, Shanmugam M, Murugesu M, Ollesch J, Stubbs G, Long JR, Safar JG, Prusiner SB. Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein. Proceedings of the National Academy of Sciences of the United States of America. 106: 3740-5. PMID 19223590 DOI: 10.1073/Pnas.0812770106 |
0.765 |
|
| 2009 |
Campana V, Zentilin L, Mirabile I, Kranjc A, Casanova P, Giacca M, Prusiner SB, Legname G, Zurzolo C. Development of antibody fragments for immunotherapy of prion diseases. The Biochemical Journal. 418: 507-15. PMID 19000036 DOI: 10.1042/Bj20081541 |
0.466 |
|
| 2008 |
Godsave SF, Wille H, Kujala P, Latawiec D, DeArmond SJ, Serban A, Prusiner SB, Peters PJ. Cryo-immunogold electron microscopy for prions: toward identification of a conversion site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12489-99. PMID 19020041 DOI: 10.1523/JNEUROSCI.4474-08.2008 |
0.398 |
|
| 2008 |
Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB. Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. Plos Pathogens. 4: e1000206. PMID 19008948 DOI: 10.1371/journal.ppat.1000206 |
0.399 |
|
| 2008 |
Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proceedings of the National Academy of Sciences of the United States of America. 105: 10595-600. PMID 18647832 DOI: 10.1073/Pnas.0803671105 |
0.426 |
|
| 2008 |
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Prusiner SB, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/Vir.0.2008/001255-0 |
0.604 |
|
| 2008 |
Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, Dearmond SJ, Prusiner SB. Transmission and detection of prions in feces. The Journal of Infectious Diseases. 198: 81-9. PMID 18505383 DOI: 10.1086/588193 |
0.426 |
|
| 2008 |
Stöhr J, Weinmann N, Wille H, Kaimann T, Nagel-Steger L, Birkmann E, Panza G, Prusiner SB, Eigen M, Riesner D. Mechanisms of prion protein assembly into amyloid. Proceedings of the National Academy of Sciences of the United States of America. 105: 2409-14. PMID 18268326 DOI: 10.1073/Pnas.0712036105 |
0.406 |
|
| 2008 |
Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Small-molecule aggregates inhibit amyloid polymerization. Nature Chemical Biology. 4: 197-9. PMID 18223646 DOI: 10.1038/Nchembio.65 |
0.525 |
|
| 2008 |
Prusiner SB. Reflections on kuru Philosophical Transactions of the Royal Society B: Biological Sciences. 363: 3654-3656. DOI: 10.1098/rstb.2008.4024 |
0.313 |
|
| 2007 |
Colby DW, Zhang Q, Wang S, Groth D, Legname G, Riesner D, Prusiner SB. Prion detection by an amyloid seeding assay. Proceedings of the National Academy of Sciences of the United States of America. 104: 20914-9. PMID 18096717 DOI: 10.1073/Pnas.0710152105 |
0.657 |
|
| 2007 |
Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB. Cell division modulates prion accumulation in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 17971-6. PMID 17989223 DOI: 10.1073/Pnas.0708372104 |
0.672 |
|
| 2007 |
Wille H, Govaerts C, Borovinskiy A, Latawiec D, Downing KH, Cohen FE, Prusiner SB. Electron crystallography of the scrapie prion protein complexed with heavy metals. Archives of Biochemistry and Biophysics. 467: 239-48. PMID 17935686 DOI: 10.1016/J.Abb.2007.08.010 |
0.544 |
|
| 2007 |
Müller H, Stitz L, Wille H, Prusiner SB, Riesner D. Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation. The Journal of Biological Chemistry. 282: 35855-67. PMID 17878157 DOI: 10.1074/jbc.M706883200 |
0.359 |
|
| 2007 |
Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Molecular Medicine (Cambridge, Mass.). 13: 190-8. PMID 17592554 DOI: 10.2119/2006-00073.Karpuj |
0.336 |
|
| 2007 |
King DJ, Safar JG, Legname G, Prusiner SB. Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites. Journal of Molecular Biology. 369: 1001-14. PMID 17481659 DOI: 10.1016/j.jmb.2007.02.004 |
0.314 |
|
| 2007 |
Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BC. Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds. The Journal of General Virology. 88: 1392-401. PMID 17374787 DOI: 10.1099/Vir.0.82601-0 |
0.573 |
|
| 2007 |
Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M, Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB. Transgenic mouse brains for the evaluation and quality control of BSE tests. Biological Chemistry. 388: 349-54. PMID 17338644 DOI: 10.1515/BC.2007.040 |
0.374 |
|
| 2007 |
Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ. Developmental expression of PrP in the post-implantation embryo. Brain Research. 1139: 60-7. PMID 17292334 DOI: 10.1016/j.brainres.2006.12.055 |
0.312 |
|
| 2007 |
May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE. Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics. Journal of Medicinal Chemistry. 50: 65-73. PMID 17201410 DOI: 10.1021/Jm061045Z |
0.538 |
|
| 2007 |
Diez M, Groth D, DeArmond SJ, Prusiner SB, Hökfelt T. Changes in neuropeptide expression in mice infected with prions. Neurobiology of Aging. 28: 748-65. PMID 16621165 DOI: 10.1016/j.neurobiolaging.2006.02.017 |
0.429 |
|
| 2007 |
Giles K, Supattapone S, Peretz D, Glidden DV, Baron H, Prusiner SB. Disinfection of prions Acs Symposium Series. 967: 52-74. |
0.645 |
|
| 2006 |
Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 103: 19105-10. PMID 17142317 DOI: 10.1073/pnas.0608970103 |
0.594 |
|
| 2006 |
Prusiner SB, McCarty M. Discovering DNA encodes heredity and prions are infectious proteins. Annual Review of Genetics. 40: 25-45. PMID 17094736 DOI: 10.1146/annurev.genet.40.121505.133522 |
0.34 |
|
| 2006 |
Luginbühl B, Kanyo Z, Jones RM, Fletterick RJ, Prusiner SB, Cohen FE, Williamson RA, Burton DR, Plückthun A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. Journal of Molecular Biology. 363: 75-97. PMID 16962610 DOI: 10.1016/J.Jmb.2006.07.027 |
0.555 |
|
| 2006 |
Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB. Transmission of elk and deer prions to transgenic mice. Journal of Virology. 80: 9104-14. PMID 16940522 DOI: 10.1128/JVI.00098-06 |
0.447 |
|
| 2006 |
Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG. Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models. Neuroimage. 33: 449-62. PMID 16931059 DOI: 10.1016/J.Neuroimage.2006.05.055 |
0.358 |
|
| 2006 |
May BC, Witkop J, Sherrill J, Anderson MO, Madrid PB, Zorn JA, Prusiner SB, Cohen FE, Guy RK. Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells. Bioorganic & Medicinal Chemistry Letters. 16: 4913-6. PMID 16860557 DOI: 10.1016/J.Bmcl.2006.06.050 |
0.523 |
|
| 2006 |
Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB. Human prions and plasma lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 11312-7. PMID 16849426 DOI: 10.1073/Pnas.0604021103 |
0.376 |
|
| 2006 |
Leclerc E, Serban H, Prusiner SB, Burton DR, Williamson RA. Copper induces conformational changes in the N-terminal part of cell-surface PrPC. Archives of Virology. 151: 2103-9. PMID 16791441 DOI: 10.1007/s00705-006-0804-1 |
0.363 |
|
| 2006 |
Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET. Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1136-44. PMID 16581945 DOI: 10.1124/Dmd.105.008664 |
0.347 |
|
| 2006 |
Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson GA. Prion infection of mouse neurospheres. Proceedings of the National Academy of Sciences of the United States of America. 103: 3875-80. PMID 16495413 DOI: 10.1073/Pnas.0510902103 |
0.458 |
|
| 2006 |
Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB. Inactivation of prions by acidic sodium dodecyl sulfate. Journal of Virology. 80: 322-31. PMID 16352557 DOI: 10.1128/Jvi.80.1.322-331.2006 |
0.677 |
|
| 2006 |
Lim KH, Nguyen TN, Damo SM, Mazur T, Ball HL, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nuclear Magnetic Resonance. 29: 183-90. PMID 16256316 DOI: 10.1016/J.Ssnmr.2005.09.017 |
0.39 |
|
| 2006 |
Nuber S, Petrasch-Parwez E, Schmidt T, Habbes H, Löbbecke-Schumacher M, Teismann P, Schulz J, Neumann M, Fendt M, Pichler B, Nguyen H, Berg D, Holzmann C, Boy J, Kuhn M, ... ... Prusiner S, et al. Characterisation of a conditional mouse-model of Parkinson's disease Aktuelle Neurologie. 33. DOI: 10.1055/S-2006-953108 |
0.323 |
|
| 2006 |
Condello C, Aoyagi A, Stöhr J, Lee JC, Rivera BM, Woerman AL, Halliday GM, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Dirk Keene C, Seeley WW, DeGrado WF, ... Prusiner SB, et al. P4-233: AGED ALZHEIMER'S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS Alzheimer's & Dementia. 14: P1531-P1532. DOI: 10.1016/J.Jalz.2018.07.054 |
0.797 |
|
| 2006 |
Legname G, Nguyen HB, Baskakov IV, DeArmond SJ, Prusiner SB. S1-03-04: Transmission studies of mouse synthetic prions Alzheimer's & Dementia. 2: S5-S5. DOI: 10.1016/J.Jalz.2006.05.022 |
0.606 |
|
| 2005 |
Kanaani J, Prusiner SB, Diacovo J, Baekkeskov S, Legname G. Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro. Journal of Neurochemistry. 95: 1373-86. PMID 16313516 DOI: 10.1111/J.1471-4159.2005.03469.X |
0.31 |
|
| 2005 |
Lee IS, Long JR, Prusiner SB, Safar JG. Selective precipitation of prions by polyoxometalate complexes. Journal of the American Chemical Society. 127: 13802-3. PMID 16201796 DOI: 10.1021/Ja055219Y |
0.478 |
|
| 2005 |
Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P. Prion clearance in bigenic mice. The Journal of General Virology. 86: 2913-23. PMID 16186247 DOI: 10.1099/vir.0.80947-0 |
0.442 |
|
| 2005 |
Safar JG, Kellings K, Serban A, Groth D, Cleaver JE, Prusiner SB, Riesner D. Search for a prion-specific nucleic acid. Journal of Virology. 79: 10796-806. PMID 16051871 DOI: 10.1128/Jvi.79.16.10796-10806.2005 |
0.393 |
|
| 2005 |
Leffers KW, Wille H, Stöhr J, Junger E, Prusiner SB, Riesner D. Assembly of natural and recombinant prion protein into fibrils. Biological Chemistry. 386: 569-80. PMID 16006244 DOI: 10.1515/BC.2005.067 |
0.458 |
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| 2005 |
Scott MR, Peretz D, Nguyen HO, Dearmond SJ, Prusiner SB. Transmission barriers for bovine, ovine, and human prions in transgenic mice. Journal of Virology. 79: 5259-71. PMID 15827140 DOI: 10.1128/JVI.79.9.5259-5271.2005 |
0.453 |
|
| 2005 |
Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. Diagnosis of human prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 3501-6. PMID 15741275 DOI: 10.1073/Pnas.0409651102 |
0.405 |
|
| 2005 |
Legname G, Nguyen HO, Baskakov IV, Cohen FE, Dearmond SJ, Prusiner SB. Strain-specified characteristics of mouse synthetic prions. Proceedings of the National Academy of Sciences of the United States of America. 102: 2168-73. PMID 15671162 DOI: 10.1073/Pnas.0409079102 |
0.713 |
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| 2005 |
Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ. Notch-1 activation and dendritic atrophy in prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 886-91. PMID 15640354 DOI: 10.1073/Pnas.0408612101 |
0.374 |
|
| 2005 |
Nuber S, Schmidt T, Habbes H, Löbbecke-Schumacher M, Teismann P, Schulz J, Pichler B, Neumann M, Fendt M, Berg D, Holzmann C, Grasshoff U, Boy J, Schmitt I, Bornemann A, ... ... Prusiner S, et al. Conditional control of human wildtype and mutated [A30P] alpha-synuclein in a mouse model of Parkinson's disease Aktuelle Neurologie. 32. DOI: 10.1055/S-2005-919318 |
0.305 |
|
| 2004 |
Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ. Pharmacokinetics of quinacrine in the treatment of prion disease. Bmc Infectious Diseases. 4: 53. PMID 15569390 DOI: 10.1186/1471-2334-4-53 |
0.387 |
|
| 2004 |
Requena JR, Dimitrova MN, Legname G, Teijeira S, Prusiner SB, Levine RL. Oxidation of methionine residues in the prion protein by hydrogen peroxide. Archives of Biochemistry and Biophysics. 432: 188-95. PMID 15542057 DOI: 10.1016/j.abb.2004.09.012 |
0.339 |
|
| 2004 |
Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ, DeArmond SJ. The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system. Journal of Neuropathology and Experimental Neurology. 63: 882-99. PMID 15330342 DOI: 10.1093/Jnen/63.8.882 |
0.31 |
|
| 2004 |
Serban A, Legname G, Hansen K, Kovaleva N, Prusiner SB. Immunoglobulins in urine of hamsters with scrapie. The Journal of Biological Chemistry. 279: 48817-20. PMID 15310752 DOI: 10.1074/jbc.M409107200 |
0.333 |
|
| 2004 |
Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB. Synthetic mammalian prions. Science (New York, N.Y.). 305: 673-6. PMID 15286374 DOI: 10.1126/Science.1100195 |
0.748 |
|
| 2004 |
Govaerts C, Wille H, Prusiner SB, Cohen FE. Evidence for assembly of prions with left-handed beta-helices into trimers. Proceedings of the National Academy of Sciences of the United States of America. 101: 8342-7. PMID 15155909 DOI: 10.1073/pnas.0402254101 |
0.525 |
|
| 2004 |
Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nature Biotechnology. 22: 724-31. PMID 15146195 DOI: 10.1038/Nbt969 |
0.777 |
|
| 2004 |
May BC, Govaerts C, Prusiner SB, Cohen FE. Prions: so many fibers, so little infectivity. Trends in Biochemical Sciences. 29: 162-5. PMID 15124628 DOI: 10.1016/j.tibs.2004.02.008 |
0.56 |
|
| 2004 |
Prusiner SB. Early evidence that a protease-resistant protein is an active component of the infectious prion. Cell. 116: S109, 1 p following . PMID 15055596 DOI: 10.1016/S0092-8674(03)01032-8 |
0.327 |
|
| 2004 |
Goldman JS, Miller BL, Safar J, de Tourreil S, Martindale JL, Prusiner SB, Geschwind MD. When sporadic disease is not sporadic: the potential for genetic etiology. Archives of Neurology. 61: 213-6. PMID 14967768 DOI: 10.1001/Archneur.61.2.213 |
0.309 |
|
| 2004 |
Baskakov IV, Legname G, Gryczynski Z, Prusiner SB. The peculiar nature of unfolding of the human prion protein. Protein Science : a Publication of the Protein Society. 13: 586-95. PMID 14767078 DOI: 10.1110/Ps.03457204 |
0.642 |
|
| 2004 |
Tremblay P, Ball HL, Kaneko K, Groth D, Hegde RS, Cohen FE, DeArmond SJ, Prusiner SB, Safar JG. Mutant PrPSc conformers induced by a synthetic peptide and several prion strains. Journal of Virology. 78: 2088-99. PMID 14747574 DOI: 10.1128/Jvi.78.4.2088-2099.2004 |
0.62 |
|
| 2004 |
Prusiner SB, May BCH, Cohen FE. 18 Therapeutic Approaches to Prion Diseases Cold Spring Harbor Monograph Archive. 41: 961-1014. DOI: 10.1101/087969693.41.961 |
0.443 |
|
| 2004 |
Prusiner SB, Legname G, Dearmond SJ, Cohen FE, Safar J, Riesner D, Kaneko K. 16 Some Strategies and Methods for the Study of Prions Cold Spring Harbor Monograph Archive. 41: 857-920. DOI: 10.1101/087969693.41.857 |
0.414 |
|
| 2004 |
Prusiner SB, Williams E, Laplanche J, Shinagawa M. 11 Scrapie, Chronic Wasting Disease, and Transmissible Mink Encephalopathy Cold Spring Harbor Monograph Archive. 41: 545-594. DOI: 10.1101/087969693.41.545 |
0.362 |
|
| 2004 |
Scott M, Peretz D, Ridley RM, Baker HF, Dearmond SJ, Prusiner SB. 9 Transgenetic Investigations of the Species Barrier and Prion Strains Cold Spring Harbor Monograph Archive. 41: 435-482. DOI: 10.1101/087969693.41.435 |
0.347 |
|
| 2004 |
Westaway D, Hood LE, Prusiner SB. 6 Doppel, a New PrP-like Mammalian Protein Cold Spring Harbor Monograph Archive. 41: 283-304. DOI: 10.1101/087969693.41.283 |
0.37 |
|
| 2004 |
Prusiner SB. 1 An Introduction to Prion Biology and Diseases Cold Spring Harbor Monograph Archive. 41: 1-87. DOI: 10.1101/087969693.41.1 |
0.301 |
|
| 2004 |
Govaerts C, Wille H, Stanley B, Prusiner SB, Cohen FE. 5 Structural Studies of Prion Proteins Cold Spring Harbor Monograph Archive. 38: 191-228. DOI: 10.1101/087969547.38.191 |
0.419 |
|
| 2004 |
Boy J, Leergaard T, Schmidt T, Holzmann C, Niwar M, Nuber S, Haas S, Prusiner S, Wree A, Bjaalie J, Riess O. Analysis of expression patterns in the brains of tet-off promoter mice Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-833469 |
0.322 |
|
| 2004 |
Nuber S, Schmidt T, Berg D, Neumann M, Holzmann C, Fendt M, Grasshoff U, Schmitt I, Bornemann A, Zimmermann F, Kuhn W, Prusiner S, Bonin M, Servadio A, Riess O. Conditional control of human wild-type and Parkinson's disease-associated mutant alpha-synuclein in transgenic mouse brain Aktuelle Neurologie. 31. DOI: 10.1055/s-2004-833272 |
0.355 |
|
| 2004 |
Ryou C, Lessard P, Freyman Y, May BC, Guglielmo JB, Baldwin MA, Craig JC, Miller B, Geschwind M, Cohen F, DeArmond SJ, Prusiner SB, Legname G. P3-378 Evaluation of the efficacy of quinacrine in animal models of prion disease Neurobiology of Aging. 25: S463. DOI: 10.1016/S0197-4580(04)81527-6 |
0.303 |
|
| 2003 |
Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB. Trafficking of prion proteins through a caveolae-mediated endosomal pathway. The Journal of Cell Biology. 162: 703-17. PMID 12925711 DOI: 10.1083/jcb.200304140 |
0.337 |
|
| 2003 |
Mironov A, Latawiec D, Wille H, Bouzamondo-Bernstein E, Legname G, Williamson RA, Burton D, DeArmond SJ, Prusiner SB, Peters PJ. Cytosolic prion protein in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7183-93. PMID 12904479 DOI: 10.1523/Jneurosci.23-18-07183.2003 |
0.358 |
|
| 2003 |
Ryou C, Legname G, Peretz D, Craig JC, Baldwin MA, Prusiner SB. Differential inhibition of prion propagation by enantiomers of quinacrine. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 837-43. PMID 12808118 DOI: 10.1097/01.Lab.0000074919.08232.A2 |
0.446 |
|
| 2003 |
Burns CS, Aronoff-Spencer E, Legname G, Prusiner SB, Antholine WE, Gerfen GJ, Peisach J, Millhauser GL. Copper coordination in the full-length, recombinant prion protein. Biochemistry. 42: 6794-803. PMID 12779334 DOI: 10.1021/Bi027138+ |
0.309 |
|
| 2003 |
Ryou C, Prusiner SB, Legname G. Cooperative binding of dominant-negative prion protein to kringle domains. Journal of Molecular Biology. 329: 323-33. PMID 12758079 DOI: 10.1016/S0022-2836(03)00342-5 |
0.353 |
|
| 2003 |
DeArmond SJ, Prusiner SB. Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. Clinics in Laboratory Medicine. 23: 1-41. PMID 12733423 DOI: 10.1016/S0272-2712(02)00041-0 |
0.408 |
|
| 2003 |
Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proceedings of the National Academy of Sciences of the United States of America. 100: 4784-9. PMID 12684540 DOI: 10.1073/Pnas.2627989100 |
0.67 |
|
| 2003 |
May BC, Fafarman AT, Hong SB, Rogers M, Deady LW, Prusiner SB, Cohen FE. Potent inhibition of scrapie prion replication in cultured cells by bis-acridines. Proceedings of the National Academy of Sciences of the United States of America. 100: 3416-21. PMID 12626750 DOI: 10.1073/pnas.2627988100 |
0.556 |
|
| 2003 |
Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA. Conformation of PrP(C) on the cell surface as probed by antibodies. Journal of Molecular Biology. 326: 475-83. PMID 12559915 DOI: 10.1016/S0022-2836(02)01365-7 |
0.328 |
|
| 2003 |
Qin K, Coomaraswamy J, Mastrangelo P, Yang Y, Lugowski S, Petromilli C, Prusiner SB, Fraser PE, Goldberg JM, Chakrabartty A, Westaway D. The PrP-like protein Doppel binds copper. The Journal of Biological Chemistry. 278: 8888-96. PMID 12482851 DOI: 10.1074/Jbc.M210875200 |
0.327 |
|
| 2002 |
Legname G, Nelken P, Guan Z, Kanyo ZF, DeArmond SJ, Prusiner SB. Prion and doppel proteins bind to granule cells of the cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 99: 16285-90. PMID 12446843 DOI: 10.1073/pnas.242611999 |
0.386 |
|
| 2002 |
Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA. Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nature Biotechnology. 20: 1147-50. PMID 12389035 DOI: 10.1038/nbt748 |
0.475 |
|
| 2002 |
Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James TL. Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry. 41: 12277-83. PMID 12369815 DOI: 10.1021/bi026129y |
0.411 |
|
| 2002 |
Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. Dominant-negative inhibition of prion replication in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 13079-84. PMID 12271119 DOI: 10.1073/pnas.182425299 |
0.608 |
|
| 2002 |
Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR. A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron. 34: 921-32. PMID 12086640 DOI: 10.1016/S0896-6273(02)00726-2 |
0.409 |
|
| 2002 |
Baskakov IV, Legname G, Baldwin MA, Prusiner SB, Cohen FE. Pathway complexity of prion protein assembly into amyloid. The Journal of Biological Chemistry. 277: 21140-8. PMID 11912192 DOI: 10.1074/Jbc.M111402200 |
0.705 |
|
| 2002 |
Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. Prions in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 3812-7. PMID 11904434 DOI: 10.1073/Pnas.052707499 |
0.637 |
|
| 2002 |
Wille H, Michelitsch MD, Guenebaut V, Supattapone S, Serban A, Cohen FE, Agard DA, Prusiner SB. Structural studies of the scrapie prion protein by electron crystallography. Proceedings of the National Academy of Sciences of the United States of America. 99: 3563-8. PMID 11891310 DOI: 10.1073/Pnas.052703499 |
0.716 |
|
| 2002 |
Nicholson EM, Mo H, Prusiner SB, Cohen FE, Marqusee S. Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation. Journal of Molecular Biology. 316: 807-15. PMID 11866533 DOI: 10.1006/Jmbi.2001.5347 |
0.71 |
|
| 2001 |
Ball HL, King DS, Cohen FE, Prusiner SB, Baldwin MA. Engineering the prion protein using chemical synthesis. The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 357-74. PMID 11892845 DOI: 10.1034/j.1399-3011.2001.00943.x |
0.603 |
|
| 2001 |
Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, Prusiner SB, DeArmond SJ. Inherited prion disease caused by the V210I mutation: transmission to transgenic mice. Neurology. 57: 2198-205. PMID 11756597 DOI: 10.1212/Wnl.57.12.2198 |
0.685 |
|
| 2001 |
Schmitt-Ulms G, Legname G, Baldwin MA, Ball HL, Bradon N, Bosque PJ, Crossin KL, Edelman GM, DeArmond SJ, Cohen FE, Prusiner SB. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. Journal of Molecular Biology. 314: 1209-25. PMID 11743735 DOI: 10.1006/jmbi.2000.5183 |
0.788 |
|
| 2001 |
Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P. Doppel-induced cerebellar degeneration in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 15288-93. PMID 11734625 DOI: 10.1073/Pnas.251550798 |
0.418 |
|
| 2001 |
Moore RC, Xiang F, Monaghan J, Han D, Zhang Z, Edström L, Anvret M, Prusiner SB. Huntington disease phenocopy is a familial prion disease. American Journal of Human Genetics. 69: 1385-8. PMID 11593450 DOI: 10.1086/324414 |
0.392 |
|
| 2001 |
Schlumpberger M, Prusiner SB, Herskowitz I. Induction of distinct [URE3] yeast prion strains. Molecular and Cellular Biology. 21: 7035-46. PMID 11564886 DOI: 10.1128/Mcb.21.20.7035-7046.2001 |
0.343 |
|
| 2001 |
Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille H, Cohen FE, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 98: 11686-90. PMID 11562491 DOI: 10.1073/Pnas.201404298 |
0.572 |
|
| 2001 |
Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature. 412: 739-43. PMID 11507642 DOI: 10.1038/35089090 |
0.763 |
|
| 2001 |
Korth C, May BC, Cohen FE, Prusiner SB. Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 9836-41. PMID 11504948 DOI: 10.1073/pnas.161274798 |
0.601 |
|
| 2001 |
Diez M, DeArmond SJ, Groth D, Prusiner SB, Hökfelt T. Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice. Neurobiology of Disease. 8: 692-9. PMID 11493033 DOI: 10.1006/nbdi.2001.0404 |
0.322 |
|
| 2001 |
Jansen K, Schäfer O, Birkmann E, Post K, Serban H, Prusiner SB, Riesner D. Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form. Biological Chemistry. 382: 683-91. PMID 11405232 DOI: 10.1515/BC.2001.081 |
0.349 |
|
| 2001 |
Requena JR, Groth D, Legname G, Stadtman ER, Prusiner SB, Levine RL. Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 7170-5. PMID 11404462 DOI: 10.1073/pnas.121190898 |
0.539 |
|
| 2001 |
Matsunaga Y, Peretz D, Williamson A, Burton D, Mehlhorn I, Groth D, Cohen FE, Prusiner SB, Baldwin MA. Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH. Proteins. 44: 110-8. PMID 11391773 DOI: 10.1002/Prot.1077 |
0.509 |
|
| 2001 |
Prusiner SB. Shattuck lecture--neurodegenerative diseases and prions. The New England Journal of Medicine. 344: 1516-26. PMID 11357156 DOI: 10.1056/NEJM200105173442006 |
0.422 |
|
| 2001 |
Baskakov IV, Legname G, Prusiner SB, Cohen FE. Folding of prion protein to its native alpha-helical conformation is under kinetic control. The Journal of Biological Chemistry. 276: 19687-90. PMID 11306559 DOI: 10.1074/Jbc.C100180200 |
0.672 |
|
| 2001 |
Rudd PM, Wormald MR, Wing DR, Prusiner SB, Dwek RA. Prion glycoprotein: structure, dynamics, and roles for the sugars. Biochemistry. 40: 3759-66. PMID 11300755 DOI: 10.1021/Bi002625F |
0.431 |
|
| 2001 |
Leclerc E, Peretz D, Ball H, Sakurai H, Legname G, Serban A, Prusiner SB, Burton DR, Williamson RA. Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form. The Embo Journal. 20: 1547-54. PMID 11285219 DOI: 10.1093/emboj/20.7.1547 |
0.433 |
|
| 2001 |
Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB. Strain-specified relative conformational stability of the scrapie prion protein. Protein Science : a Publication of the Protein Society. 10: 854-63. PMID 11274476 DOI: 10.1110/ps.39201 |
0.546 |
|
| 2001 |
Harrison PM, Chan HS, Prusiner SB, Cohen FE. Conformational propagation with prion-like characteristics in a simple model of protein folding. Protein Science : a Publication of the Protein Society. 10: 819-35. PMID 11274473 DOI: 10.1110/ps.38701 |
0.543 |
|
| 2001 |
Supattapone S, Bouzamondo E, Ball HL, Wille H, Nguyen HO, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice. Molecular and Cellular Biology. 21: 2608-16. PMID 11259607 DOI: 10.1128/MCB.21.7.2608-2616.2001 |
0.739 |
|
| 2001 |
Viles JH, Donne D, Kroon G, Prusiner SB, Cohen FE, Dyson HJ, Wright PE. Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics. Biochemistry. 40: 2743-53. PMID 11258885 DOI: 10.1021/Bi002898A |
0.574 |
|
| 2001 |
Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. Branched polyamines cure prion-infected neuroblastoma cells. Journal of Virology. 75: 3453-61. PMID 11238871 DOI: 10.1128/Jvi.75.7.3453-3461.2001 |
0.747 |
|
| 2001 |
Mo H, Moore RC, Cohen FE, Westaway D, Prusiner SB, Wright PE, Dyson HJ. Two different neurodegenerative diseases caused by proteins with similar structures. Proceedings of the National Academy of Sciences of the United States of America. 98: 2352-7. PMID 11226243 DOI: 10.1073/Pnas.051627998 |
0.6 |
|
| 2001 |
Supattapone S, Muramoto T, Legname G, Mehlhorn I, Cohen FE, DeArmond SJ, Prusiner SB, Scott MR. Identification of two prion protein regions that modify scrapie incubation time. Journal of Virology. 75: 1408-13. PMID 11152514 DOI: 10.1128/JVI.75.3.1408-1413.2001 |
0.749 |
|
| 2000 |
Safar J, Cohen FE, Prusiner SB. Quantitative traits of prion strains are enciphered in the conformation of the prion protein. Archives of Virology. Supplementum. 227-35. PMID 11214926 DOI: 10.1007/978-3-7091-6308-5_22 |
0.558 |
|
| 2000 |
Scott MR, Supattapone S, Nguyen HO, DeArmond SJ, Prusiner SB. Transgenic models of prion disease. Archives of Virology. Supplementum. 113-24. PMID 11214913 DOI: 10.1007/978-3-7091-6308-5_10 |
0.708 |
|
| 2000 |
Supattapone S, Nguyen HO, Muramoto T, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations. Journal of Virology. 74: 11928-34. PMID 11090193 DOI: 10.1128/JVI.74.24.11928-11934.2000 |
0.749 |
|
| 2000 |
Aronoff-Spencer E, Burns CS, Avdievich NI, Gerfen GJ, Peisach J, Antholine WE, Ball HL, Cohen FE, Prusiner SB, Millhauser GL. Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy. Biochemistry. 39: 13760-71. PMID 11076515 DOI: 10.1021/Bi001472T |
0.471 |
|
| 2000 |
Stephenson DA, Chiotti K, Ebeling C, Groth D, DeArmond SJ, Prusiner SB, Carlson GA. Quantitative trait loci affecting prion incubation time in mice. Genomics. 69: 47-53. PMID 11013074 DOI: 10.1006/geno.2000.6320 |
0.432 |
|
| 2000 |
Korth C, Kaneko K, Prusiner SB. Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains. The Journal of General Virology. 81: 2555-63. PMID 10993946 DOI: 10.1099/0022-1317-81-10-2555 |
0.439 |
|
| 2000 |
Wille H, Prusiner SB, Cohen FE. Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein. Journal of Structural Biology. 130: 323-38. PMID 10940236 DOI: 10.1006/jsbi.2000.4242 |
0.586 |
|
| 2000 |
Inouye H, Bond J, Baldwin MA, Ball HL, Prusiner SB, Kirschner DA. Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions. Journal of Molecular Biology. 300: 1283-96. PMID 10903869 DOI: 10.1006/Jmbi.2000.3926 |
0.318 |
|
| 2000 |
Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D. Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss. The Journal of Biological Chemistry. 275: 26834-41. PMID 10842180 DOI: 10.1074/jbc.M003888200 |
0.602 |
|
| 2000 |
Perrier V, Wallace AC, Kaneko K, Safar J, Prusiner SB, Cohen FE. Mimicking dominant negative inhibition of prion replication through structure-based drug design. Proceedings of the National Academy of Sciences of the United States of America. 97: 6073-8. PMID 10823951 DOI: 10.1073/pnas.97.11.6073 |
0.553 |
|
| 2000 |
Bosque PJ, Prusiner SB. Cultured cell sublines highly susceptible to prion infection. Journal of Virology. 74: 4377-86. PMID 10756052 DOI: 10.1128/JVI.74.9.4377-4386.2000 |
0.35 |
|
| 2000 |
Zulianello L, Kaneko K, Scott M, Erpel S, Han D, Cohen FE, Prusiner SB. Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein. Journal of Virology. 74: 4351-60. PMID 10756050 DOI: 10.1128/JVI.74.9.4351-4360.2000 |
0.553 |
|
| 2000 |
Schlumpberger M, Wille H, Baldwin MA, Butler DA, Herskowitz I, Prusiner SB. The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein. Protein Science : a Publication of the Protein Society. 9: 440-51. PMID 10752606 DOI: 10.1110/Ps.9.3.440 |
0.399 |
|
| 2000 |
Whittal RM, Ball HL, Cohen FE, Burlingame AL, Prusiner SB, Baldwin MA. Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Science : a Publication of the Protein Society. 9: 332-43. PMID 10716185 DOI: 10.1110/Ps.9.2.332 |
0.47 |
|
| 2000 |
Baskakov IV, Aagaard C, Mehlhorn I, Wille H, Groth D, Baldwin MA, Prusiner SB, Cohen FE. Self-assembly of recombinant prion protein of 106 residues. Biochemistry. 39: 2792-804. PMID 10704232 DOI: 10.1021/Bi9923353 |
0.718 |
|
| 2000 |
Kaneko K, Ball HL, Wille H, Zhang H, Groth D, Torchia M, Tremblay P, Safar J, Prusiner SB, DeArmond SJ, Baldwin MA, Cohen FE. A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice. Journal of Molecular Biology. 295: 997-1007. PMID 10656806 DOI: 10.1006/jmbi.1999.3386 |
0.578 |
|
| 1999 |
Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR. Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature. 402: 822-6. PMID 10617204 DOI: 10.1038/45574 |
0.444 |
|
| 1999 |
Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proceedings of the National Academy of Sciences of the United States of America. 96: 15137-42. PMID 10611351 DOI: 10.1073/pnas.96.26.15137 |
0.465 |
|
| 1999 |
Tatzelt J, Groth DF, Torchia M, Prusiner SB, DeArmond SJ. Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie. Journal of Neuropathology and Experimental Neurology. 58: 1244-9. PMID 10604749 DOI: 10.1097/00005072-199912000-00005 |
0.409 |
|
| 1999 |
Supattapone S, Nguyen HO, Cohen FE, Prusiner SB, Scott MR. Elimination of prions by branched polyamines and implications for therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 96: 14529-34. PMID 10588739 DOI: 10.1073/pnas.96.25.14529 |
0.726 |
|
| 1999 |
Rudd PM, Endo T, Colominas C, Groth D, Wheeler SF, Harvey DJ, Wormald MR, Serban H, Prusiner SB, Kobata A, Dwek RA. Glycosylation differences between the normal and pathogenic prion protein isoforms. Proceedings of the National Academy of Sciences of the United States of America. 96: 13044-9. PMID 10557270 DOI: 10.1073/Pnas.96.23.13044 |
0.458 |
|
| 1999 |
Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE. Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. Journal of Molecular Biology. 293: 855-63. PMID 10543972 DOI: 10.1006/Jmbi.1999.3193 |
0.515 |
|
| 1999 |
Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, ... ... Prusiner SB, et al. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. Journal of Molecular Biology. 292: 797-817. PMID 10525406 DOI: 10.1006/jmbi.1999.3108 |
0.615 |
|
| 1999 |
Mastrianni JA, Nixon R, Layzer R, Telling GC, Han D, DeArmond SJ, Prusiner SB. Prion protein conformation in a patient with sporadic fatal insomnia. The New England Journal of Medicine. 340: 1630-8. PMID 10341275 DOI: 10.1056/Nejm199905273402104 |
0.676 |
|
| 1999 |
Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 38: 5362-77. PMID 10220323 DOI: 10.1021/Bi982878X |
0.741 |
|
| 1999 |
Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, Nguyen HO, Heinrich C, Torchia M, Safar J, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice. Cell. 96: 869-78. PMID 10102274 DOI: 10.1016/S0092-8674(00)80596-6 |
0.763 |
|
| 1999 |
Viles JH, Cohen FE, Prusiner SB, Goodin DB, Wright PE, Dyson HJ. Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proceedings of the National Academy of Sciences of the United States of America. 96: 2042-7. PMID 10051591 DOI: 10.1073/Pnas.96.5.2042 |
0.477 |
|
| 1999 |
Harrison PM, Chan HS, Prusiner SB, Cohen FE. Thermodynamics of model prions and its implications for the problem of prion protein folding. Journal of Molecular Biology. 286: 593-606. PMID 9973573 DOI: 10.1006/jmbi.1998.2497 |
0.576 |
|
| 1999 |
Wille H, Prusiner SB. Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions. Biophysical Journal. 76: 1048-62. PMID 9916037 DOI: 10.1016/S0006-3495(99)77270-X |
0.368 |
|
| 1999 |
Prusiner SB. Preface/Front Matter Cold Spring Harbor Monograph Archive. 38. DOI: 10.1101/087969547.38.I |
0.371 |
|
| 1999 |
Baron H, Safar J, Groth D, Dearmond SJ, Prusiner SB. 17 Biosafety Issues in Prion Diseases Cold Spring Harbor Monograph Archive. 38: 743-777. DOI: 10.1101/087969547.38.743 |
0.456 |
|
| 1999 |
Prusiner SB. 2 Development of the Prion Concept Cold Spring Harbor Monograph Archive. 38: 67-112. DOI: 10.1101/087969547.38.67 |
0.303 |
|
| 1999 |
Prusiner SB, Kaneko K, Serban H, Cohen FE, Safar J, Riesner D. 15 Some Strategies and Methods for the Study of Prions Cold Spring Harbor Monograph Archive. 38: 653-715. DOI: 10.1101/087969547.38.653 |
0.471 |
|
| 1999 |
Prusiner SB, Peters P, Kaneko K, Taraboulos A, Lingappa V, Cohen FE, Dearmond SJ. 10 Cell Biology of Prions Cold Spring Harbor Monograph Archive. 38: 349-391. DOI: 10.1101/087969547.38.349 |
0.305 |
|
| 1999 |
Prusiner SB, Scott MR, Dearmond SJ, Carlson G. 4 Transmission and Replication of Prions Cold Spring Harbor Monograph Archive. 38: 147-190. DOI: 10.1101/087969547.38.147 |
0.36 |
|
| 1999 |
Prusiner SB, Tremblay P, Safar J, Torchia M, Dearmond SJ. 3 Bioassays of Prions Cold Spring Harbor Monograph Archive. 38: 113-145. DOI: 10.1101/087969547.38.113 |
0.334 |
|
| 1999 |
Scott M, Dearmond SJ, Prusiner SB, Ridley RM, Baker HF. 8 Transgenetic Investigations of the Species Barrier and Prion Strains Cold Spring Harbor Monograph Archive. 38: 307-347. DOI: 10.1101/0.307-347 |
0.348 |
|
| 1998 |
Safar J, Prusiner SB. Molecular studies of prion diseases. Progress in Brain Research. 117: 421-34. PMID 9932423 DOI: 10.1016/S0079-6123(08)64030-3 |
0.418 |
|
| 1998 |
Post K, Pitschke M, Schäfer O, Wille H, Appel TR, Kirsch D, Mehlhorn I, Serban H, Prusiner SB, Riesner D. Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation. Biological Chemistry. 379: 1307-17. PMID 9865603 DOI: 10.1515/Bchm.1998.379.11.1307 |
0.365 |
|
| 1998 |
Prusiner SB. Prions. Proceedings of the National Academy of Sciences of the United States of America. 95: 13363-83. PMID 9811807 DOI: 10.1073/PNAS.95.23.13363 |
0.434 |
|
| 1998 |
Lee IY, Westaway D, Smit AF, Wang K, Seto J, Chen L, Acharya C, Ankener M, Baskin D, Cooper C, Yao H, Prusiner SB, Hood LE. Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Research. 8: 1022-37. PMID 9799790 DOI: 10.1101/gr.8.10.1022 |
0.317 |
|
| 1998 |
Safar J, Wille H, Itri V, Groth D, Serban H, Torchia M, Cohen FE, Prusiner SB. Eight prion strains have PrP(Sc) molecules with different conformations. Nature Medicine. 4: 1157-65. PMID 9771749 DOI: 10.1038/2654 |
0.545 |
|
| 1998 |
Tremblay P, Meiner Z, Galou M, Heinrich C, Petromilli C, Lisse T, Cayetano J, Torchia M, Mobley W, Bujard H, DeArmond SJ, Prusiner SB. Doxycycline control of prion protein transgene expression modulates prion disease in mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 12580-5. PMID 9770528 DOI: 10.1073/Pnas.95.21.12580 |
0.425 |
|
| 1998 |
Baldwin MA, James TL, Cohen FE, Prusiner SB. The three-dimensional structure of prion protein: implications for prion disease. Biochemical Society Transactions. 26: 481-6. PMID 9765900 DOI: 10.1042/Bst0260481 |
0.581 |
|
| 1998 |
Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR. Mapping the prion protein using recombinant antibodies. Journal of Virology. 72: 9413-8. PMID 9765500 DOI: 10.1128/JVI.72.11.9413-9418.1998 |
0.42 |
|
| 1998 |
Cohen FE, Prusiner SB. Pathologic conformations of prion proteins. Annual Review of Biochemistry. 67: 793-819. PMID 9759504 DOI: 10.1146/annurev.biochem.67.1.793 |
0.599 |
|
| 1998 |
Prusiner SB. The prion diseases. Brain Pathology (Zurich, Switzerland). 8: 499-513. PMID 9669700 DOI: 10.1111/J.1750-3639.1998.Tb00171.X |
0.424 |
|
| 1998 |
Prusiner SB, Scott MR, DeArmond SJ, Cohen FE. Prion protein biology. Cell. 93: 337-48. PMID 9590169 DOI: 10.1016/S0092-8674(00)81163-0 |
0.465 |
|
| 1998 |
Stöckel J, Safar J, Wallace AC, Cohen FE, Prusiner SB. Prion protein selectively binds copper(II) ions. Biochemistry. 37: 7185-93. PMID 9585530 DOI: 10.1021/bi972827k |
0.497 |
|
| 1998 |
Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. A transmembrane form of the prion protein in neurodegenerative disease. Science (New York, N.Y.). 279: 827-34. PMID 9452375 DOI: 10.1126/Science.279.5352.827 |
0.508 |
|
| 1997 |
Blochberger TC, Cooper C, Peretz D, Tatzelt J, Griffith OH, Baldwin MA, Prusiner SB. Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system. Protein Engineering. 10: 1465-73. PMID 9543009 DOI: 10.1093/Protein/10.12.1465 |
0.39 |
|
| 1997 |
Prusiner SB, Scott MR. Genetics of prions. Annual Review of Genetics. 31: 139-75. PMID 9442893 DOI: 10.1146/annurev.genet.31.1.139 |
0.457 |
|
| 1997 |
DeArmond SJ, Sánchez H, Yehiely F, Qiu Y, Ninchak-Casey A, Daggett V, Camerino AP, Cayetano J, Rogers M, Groth D, Torchia M, Tremblay P, Scott MR, Cohen FE, Prusiner SB. Selective neuronal targeting in prion disease. Neuron. 19: 1337-48. PMID 9427256 DOI: 10.1016/S0896-6273(00)80424-9 |
0.592 |
|
| 1997 |
Scott MR, Safar J, Telling G, Nguyen O, Groth D, Torchia M, Koehler R, Tremblay P, Walther D, Cohen FE, DeArmond SJ, Prusiner SB. Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 14279-84. PMID 9405603 DOI: 10.1073/pnas.94.26.14279 |
0.604 |
|
| 1997 |
Donne DG, Viles JH, Groth D, Mehlhorn I, James TL, Cohen FE, Prusiner SB, Wright PE, Dyson HJ. Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible. Proceedings of the National Academy of Sciences of the United States of America. 94: 13452-7. PMID 9391046 DOI: 10.1073/pnas.94.25.13452 |
0.535 |
|
| 1997 |
Scott MR, Groth D, Tatzelt J, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Propagation of prion strains through specific conformers of the prion protein. Journal of Virology. 71: 9032-44. PMID 9371560 DOI: 10.1128/Jvi.71.12.9032-9044.1997 |
0.426 |
|
| 1997 |
Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James TL, Houghten RA, Cohen FE, Prusiner SB, Burton DR. A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. Journal of Molecular Biology. 273: 614-22. PMID 9356250 DOI: 10.1006/jmbi.1997.1328 |
0.558 |
|
| 1997 |
Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB. A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. Journal of Virology. 71: 8821-31. PMID 9343242 DOI: 10.1128/Jvi.71.11.8821-8831.1997 |
0.337 |
|
| 1997 |
Prusiner SB. Prion diseases and the BSE crisis. Science (New York, N.Y.). 278: 245-51. PMID 9323196 DOI: 10.1126/Science.278.5336.245 |
0.456 |
|
| 1997 |
James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 94: 10086-91. PMID 9294167 DOI: 10.1073/pnas.94.19.10086 |
0.578 |
|
| 1997 |
Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James TL, Cohen FE, Prusiner SB. Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proceedings of the National Academy of Sciences of the United States of America. 94: 10069-74. PMID 9294164 DOI: 10.1073/pnas.94.19.10069 |
0.597 |
|
| 1997 |
Meiner Z, Gabizon R, Prusiner SB. Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews. Medicine. 76: 227-37. PMID 9279329 DOI: 10.1097/00005792-199707000-00001 |
0.433 |
|
| 1997 |
Kaneko K, Wille H, Mehlhorn I, Zhang H, Ball H, Cohen FE, Baldwin MA, Prusiner SB. Molecular properties of complexes formed between the prion protein and synthetic peptides. Journal of Molecular Biology. 270: 574-86. PMID 9245588 DOI: 10.1006/jmbi.1997.1135 |
0.543 |
|
| 1997 |
Muramoto T, DeArmond SJ, Scott M, Telling GC, Cohen FE, Prusiner SB. Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix. Nature Medicine. 3: 750-5. PMID 9212101 DOI: 10.1038/nm0797-750 |
0.723 |
|
| 1997 |
Lundberg KM, Stenland CJ, Cohen FE, Prusiner SB, Millhauser GL. Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR. Chemistry & Biology. 4: 345-55. PMID 9195875 DOI: 10.1016/S1074-5521(97)90125-3 |
0.536 |
|
| 1997 |
Yehiely F, Bamborough P, Da Costa M, Perry BJ, Thinakaran G, Cohen FE, Carlson GA, Prusiner SB. Identification of candidate proteins binding to prion protein. Neurobiology of Disease. 3: 339-55. PMID 9173930 DOI: 10.1006/Nbdi.2002.0484 |
0.451 |
|
| 1997 |
Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James TL, Cohen FE. Physical studies of conformational plasticity in a recombinant prion protein. Biochemistry. 36: 3543-53. PMID 9132005 DOI: 10.1021/bi961965r |
0.533 |
|
| 1997 |
Kaneko K, Vey M, Scott M, Pilkuhn S, Cohen FE, Prusiner SB. COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 94: 2333-8. PMID 9122195 DOI: 10.1073/Pnas.94.6.2333 |
0.577 |
|
| 1997 |
Telling GC, Tremblay P, Torchia M, Dearmond SJ, Cohen FE, Prusiner SB. N-terminally tagged prion protein supports prion propagation in transgenic mice. Protein Science : a Publication of the Protein Society. 6: 825-33. PMID 9098892 DOI: 10.1002/pro.5560060409 |
0.735 |
|
| 1997 |
Carlson GA, Banks S, Lund D, Reichert C, Groth D, Torchia M, Dearmond SJ, Prusiner SB. Failure to transmit disease from gray tremor mutant mice. Journal of Virology. 71: 2342-5. PMID 9032370 DOI: 10.1128/Jvi.71.3.2342-2345.1997 |
0.39 |
|
| 1997 |
Harrison PM, Bamborough P, Daggett V, Prusiner SB, Cohen FE. The prion folding problem. Current Opinion in Structural Biology. 7: 53-9. PMID 9032055 DOI: 10.1016/S0959-440X(97)80007-3 |
0.555 |
|
| 1997 |
Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. Prion protein gene variation among primates. Journal of Molecular Biology. 265: 257. PMID 9020986 DOI: 10.1006/jmbi.1996.0791 |
0.45 |
|
| 1997 |
Meiner Z, Rosental Y, Vey M, Pilkuhn S, Prusiner S. Fusion of prion protein to green fluorescent protein facilitates subcellular localization Neuroscience Letters. 237: S35. DOI: 10.1016/S0304-3940(97)90144-0 |
0.314 |
|
| 1997 |
Prusiner S. Detecting prions in a sample and prion preparation and transgenic animal used for same Biofutur. 1997: 48. DOI: 10.1016/S0294-3506(99)80368-8 |
0.386 |
|
| 1996 |
DeArmond SJ, Qiu Y, Wong K, Nixon R, Hyun W, Prusiner SB, Mobley WC. Abnormal plasma membrane properties and functions in prion-infected cell lines. Cold Spring Harbor Symposia On Quantitative Biology. 61: 531-40. PMID 9246479 DOI: 10.1101/Sqb.1996.061.01.053 |
0.32 |
|
| 1996 |
Bamborough P, Wille H, Telling GC, Yehiely F, Prusiner SB, Cohen FE. Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations. Cold Spring Harbor Symposia On Quantitative Biology. 61: 495-509. PMID 9246476 DOI: 10.1101/Sqb.1996.061.01.050 |
0.676 |
|
| 1996 |
Prusiner SB. Molecular biology and genetics of prion diseases. Cold Spring Harbor Symposia On Quantitative Biology. 61: 473-93. PMID 9246475 DOI: 10.1101/Sqb.1996.061.01.049 |
0.314 |
|
| 1996 |
Huang Z, Prusiner SB, Cohen FE. Scrapie prions: a three-dimensional model of an infectious fragment. Folding & Design. 1: 13-9. PMID 9079359 DOI: 10.1016/S1359-0278(96)00007-7 |
0.383 |
|
| 1996 |
Prusiner SB. Molecular biology and pathogenesis of prion diseases. Trends in Biochemical Sciences. 21: 482-7. PMID 9009832 DOI: 10.1016/S0968-0004(96)10063-3 |
0.434 |
|
| 1996 |
Muramoto T, Scott M, Cohen FE, Prusiner SB. Recombinant scrapie-like prion protein of 106 amino acids is soluble. Proceedings of the National Academy of Sciences of the United States of America. 93: 15457-62. PMID 8986833 DOI: 10.1073/Pnas.93.26.15457 |
0.567 |
|
| 1996 |
Tatzelt J, Prusiner SB, Welch WJ. Chemical chaperones interfere with the formation of scrapie prion protein. The Embo Journal. 15: 6363-73. PMID 8978663 DOI: 10.1002/J.1460-2075.1996.Tb01027.X |
0.445 |
|
| 1996 |
Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A, Prusiner SB. Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proceedings of the National Academy of Sciences of the United States of America. 93: 14945-9. PMID 8962161 DOI: 10.1073/pnas.93.25.14945 |
0.366 |
|
| 1996 |
Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science (New York, N.Y.). 274: 2079-82. PMID 8953038 DOI: 10.1126/Science.274.5295.2079 |
0.707 |
|
| 1996 |
Wille H, Baldwin MA, Cohen FE, DeArmond SJ, Prusiner SB. Prion protein amyloid: separation of scrapie infectivity from PrP polymers. Ciba Foundation Symposium. 199: 181-99; discussion 1. PMID 8915611 |
0.531 |
|
| 1996 |
Mastrianni JA, Iannicola C, Myers RM, DeArmond S, Prusiner SB. Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease. Neurology. 47: 1305-12. PMID 8909447 DOI: 10.1212/Wnl.47.5.1305 |
0.369 |
|
| 1996 |
Diez M, Koistinaho J, DeArmond SJ, Camerino AP, Groth D, Caytano JC, Prusiner SB, Hökfelt T. Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice. Neuroreport. 7: 1887-92. PMID 8905686 DOI: 10.1097/00001756-199608120-00003 |
0.318 |
|
| 1996 |
Prusiner SB. Prion biology and diseases--laughing cannibals, mad cows, and scientific heresy. Medicinal Research Reviews. 16: 487-505. PMID 8865151 DOI: 10.1002/(SICI)1098-1128(199609)16:5<487::AID-MED4>3.0.CO;2-R |
0.37 |
|
| 1996 |
Heller J, Kolbert AC, Larsen R, Ernst M, Bekker T, Baldwin M, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR studies of the prion protein H1 fragment. Protein Science : a Publication of the Protein Society. 5: 1655-61. PMID 8844854 DOI: 10.1002/Pro.5560050819 |
0.346 |
|
| 1996 |
Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB. Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein. Neurology. 47: 449-53. PMID 8757019 DOI: 10.1212/WNL.47.2.449 |
0.419 |
|
| 1996 |
Telling GC, Haga T, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes & Development. 10: 1736-50. PMID 8698234 DOI: 10.1101/Gad.10.14.1736 |
0.668 |
|
| 1996 |
Williamson RA, Peretz D, Smorodinsky N, Bastidas R, Serban H, Mehlhorn I, DeArmond SJ, Prusiner SB, Burton DR. Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 7279-82. PMID 8692983 DOI: 10.1073/pnas.93.14.7279 |
0.393 |
|
| 1996 |
Wille H, Zhang GF, Baldwin MA, Cohen FE, Prusiner SB. Separation of scrapie prion infectivity from PrP amyloid polymers. Journal of Molecular Biology. 259: 608-21. PMID 8683568 DOI: 10.1006/jmbi.1996.0343 |
0.579 |
|
| 1996 |
Lledo PM, Tremblay P, DeArmond SJ, Prusiner SB, Nicoll RA. Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 93: 2403-7. PMID 8637886 DOI: 10.1073/pnas.93.6.2403 |
0.363 |
|
| 1996 |
Riesner D, Kellings K, Post K, Wille H, Serban H, Groth D, Baldwin MA, Prusiner SB. Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity. Journal of Virology. 70: 1714-22. PMID 8627692 DOI: 10.1128/Jvi.70.3.1714-1722.1996 |
0.35 |
|
| 1996 |
Mehlhorn I, Groth D, Stöckel J, Moffat B, Reilly D, Yansura D, Willett WS, Baldwin M, Fletterick R, Cohen FE, Vandlen R, Henner D, Prusiner SB. High-level expression and characterization of a purified 142-residue polypeptide of the prion protein. Biochemistry. 35: 5528-37. PMID 8611544 DOI: 10.1021/bi952965e |
0.524 |
|
| 1996 |
Prusiner SB. Transgenetics of prion diseases. Current Topics in Microbiology and Immunology. 206: 275-304. PMID 8608721 DOI: 10.1007/978-3-642-85208-4_14 |
0.365 |
|
| 1996 |
Scott MR, Telling GC, Prusiner SB. Transgenetics and gene targeting in studies of prion diseases. Current Topics in Microbiology and Immunology. 207: 95-123. PMID 8575209 DOI: 10.1007/978-3-642-60983-1_8 |
0.641 |
|
| 1996 |
Huang Z, Prusiner SB, Cohen FE. Structures of prion proteins and conformational models for prion diseases. Current Topics in Microbiology and Immunology. 207: 49-67. PMID 8575206 DOI: 10.1007/978-3-642-60983-1_5 |
0.523 |
|
| 1996 |
DeArmond SJ, Prusiner SB. Transgenetics and neuropathology of prion diseases. Current Topics in Microbiology and Immunology. 207: 125-46. PMID 8575201 DOI: 10.1007/978-3-642-60983-1_9 |
0.486 |
|
| 1996 |
Prusiner SB. Human prion diseases and neurodegeneration. Current Topics in Microbiology and Immunology. 207: 1-17. PMID 8575200 DOI: 10.1007/978-3-642-60983-1_1 |
0.339 |
|
| 1996 |
Gabizon R, Telling G, Meiner Z, Halimi M, Kahana I, Prusiner SB. Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease. Nature Medicine. 2: 59-64. PMID 8564843 DOI: 10.1038/nm0196-59 |
0.67 |
|
| 1996 |
Guan Z, Söderberg M, Sindelar P, Prusiner SB, Kristensson K, Dallner G. Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone. Journal of Neurochemistry. 66: 277-85. PMID 8522965 DOI: 10.1046/J.1471-4159.1996.66010277.X |
0.342 |
|
| 1996 |
Nixon R, Mastrianni J, Roberts J, Prusiner S, DeArmond S. SPORADIC OCCURRENCE OF FATAL THALAMIC INSOMNIA WITHOUT A PRION PROTEIN GENE MUTATION Journal of Neuropathology and Experimental Neurology. 55: 661. DOI: 10.1097/00005072-199605000-00232 |
0.316 |
|
| 1996 |
Kazmirski SL, Alonso DOV, Cohen FE, Prusiner SB, Daggett V. The conformational consequences of mutations to the H1 helix of the prion protein explored by molecular dynamics simulations Techniques in Protein Chemistry. 7: 469-477. DOI: 10.1016/S1080-8914(96)80051-2 |
0.385 |
|
| 1996 |
Prusiner SB, Telling G, Cohen FE, DeArmond SJ. Prion diseases of humans and animals Seminars in Virology. 7: 159-173. DOI: 10.1006/smvy.1996.0021 |
0.726 |
|
| 1996 |
Prusiner SB. Introduction: Prion diseases Seminars in Virology. 7: 157. DOI: 10.1006/SMVY.1996.0020 |
0.382 |
|
| 1995 |
Kazmirski SL, Alonso DO, Cohen FE, Prusiner SB, Daggett V. Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation. Chemistry & Biology. 2: 305-15. PMID 9383432 DOI: 10.1016/1074-5521(95)90049-7 |
0.549 |
|
| 1995 |
Spudich S, Mastrianni JA, Wrensch M, Gabizon R, Meiner Z, Kahana I, Rosenmann H, Kahana E, Prusiner SB. Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene. Molecular Medicine (Cambridge, Mass.). 1: 607-13. PMID 8529127 DOI: 10.1007/Bf03401601 |
0.407 |
|
| 1995 |
Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. Prion protein gene variation among primates. Journal of Molecular Biology. 245: 362-74. PMID 7837269 DOI: 10.1006/JMBI.1994.0030 |
0.567 |
|
| 1995 |
Prusiner SB. The prion diseases. Scientific American. 272: 48-51, 54-7. PMID 7824915 DOI: 10.1038/Scientificamerican0195-48 |
0.38 |
|
| 1995 |
DeArmond SJ, Prusiner SB. Prion protein transgenes and the neuropathology in prion diseases. Brain Pathology (Zurich, Switzerland). 5: 77-89. PMID 7767493 DOI: 10.1111/J.1750-3639.1995.Tb00579.X |
0.508 |
|
| 1995 |
Tatzelt J, Zuo J, Voellmy R, Scott M, Hartl U, Prusiner SB, Welch WJ. Scrapie prions selectively modify the stress response in neuroblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 2944-8. PMID 7708753 DOI: 10.1073/Pnas.92.7.2944 |
0.318 |
|
| 1995 |
Nguyen J, Baldwin MA, Cohen FE, Prusiner SB. Prion protein peptides induce alpha-helix to beta-sheet conformational transitions. Biochemistry. 34: 4186-92. PMID 7703230 DOI: 10.1021/Bi00013A006 |
0.493 |
|
| 1995 |
Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D. Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. The Journal of Cell Biology. 129: 121-32. PMID 7698979 DOI: 10.1083/JCB.129.1.121 |
0.34 |
|
| 1995 |
Baldwin MA, Cohen FE, Prusiner SB. Prion protein isoforms, a convergence of biological and structural investigations. The Journal of Biological Chemistry. 270: 19197-200. PMID 7642588 DOI: 10.1074/Jbc.270.33.19197 |
0.536 |
|
| 1995 |
Westaway D, Carlson GA, Prusiner SB. On safari with PrP: prion diseases of animals. Trends in Microbiology. 3: 141-7. PMID 7613755 DOI: 10.1016/S0966-842X(00)88903-9 |
0.449 |
|
| 1995 |
Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA. X-ray diffraction of scrapie prion rods and PrP peptides. Journal of Molecular Biology. 252: 412-22. PMID 7563061 DOI: 10.1006/Jmbi.1995.0507 |
0.546 |
|
| 1995 |
Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell. 83: 79-90. PMID 7553876 DOI: 10.1016/0092-8674(95)90236-8 |
0.742 |
|
| 1995 |
Raeber AJ, Muramoto T, Kornberg TB, Prusiner SB. Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster. Mechanisms of Development. 51: 317-27. PMID 7547477 DOI: 10.1016/0925-4773(95)00379-7 |
0.387 |
|
| 1995 |
Zhang H, Kaneko K, Nguyen JT, Livshits TL, Baldwin MA, Cohen FE, James TL, Prusiner SB. Conformational transitions in peptides containing two putative alpha-helices of the prion protein. Journal of Molecular Biology. 250: 514-26. PMID 7542350 DOI: 10.1006/jmbi.1995.0395 |
0.515 |
|
| 1995 |
Mastrianni JA, Curtis MT, Oberholtzer JC, Da Costa MM, DeArmond S, Prusiner SB, Garbern JY. Prion disease (PrP-A117V) presenting with ataxia instead of dementia. Neurology. 45: 2042-50. PMID 7501157 DOI: 10.1212/Wnl.45.11.2042 |
0.319 |
|
| 1995 |
Kaneko K, Peretz D, Pan KM, Blochberger TC, Wille H, Gabizon R, Griffith OH, Cohen FE, Baldwin MA, Prusiner SB. Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 92: 11160-4. PMID 7479957 DOI: 10.1073/pnas.92.24.11160 |
0.529 |
|
| 1995 |
Prusiner SB, Dearmond SJ. Prion protein amyloid and neurodegeneration Amyloid. 2: 39-65. DOI: 10.3109/13506129509031887 |
0.411 |
|
| 1994 |
Jefferys JG, Empson RM, Whittington MA, Prusiner SB. Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones. Neurobiology of Disease. 1: 25-30. PMID 9216983 DOI: 10.1006/Nbdi.1994.0004 |
0.412 |
|
| 1994 |
Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson GA, Prusiner SB. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell. 76: 117-29. PMID 8287472 DOI: 10.1016/0092-8674(94)90177-5 |
0.438 |
|
| 1994 |
Prusiner SB, DeArmond SJ. Prion diseases and neurodegeneration. Annual Review of Neuroscience. 17: 311-39. PMID 8210178 DOI: 10.1146/annurev.ne.17.030194.001523 |
0.448 |
|
| 1994 |
Prusiner SB. Inherited prion diseases. Proceedings of the National Academy of Sciences of the United States of America. 91: 4611-4. PMID 8197105 DOI: 10.1073/Pnas.91.11.4611 |
0.382 |
|
| 1994 |
Prusiner SB, Hsiao KK. Human prion diseases. Annals of Neurology. 35: 385-95. PMID 8154865 DOI: 10.1002/ana.410350404 |
0.443 |
|
| 1994 |
Prusiner SB. Transgenetics and cell biology of prion diseases: investigations of PrPSc synthesis and diversity. British Medical Bulletin. 49: 873-912. PMID 8137134 DOI: 10.1093/OXFORDJOURNALS.BMB.A072652 |
0.407 |
|
| 1994 |
Fink JK, Peacock ML, Warren JT, Roses AD, Prusiner SB. Detecting prion protein gene mutations by denaturing gradient gel electrophoresis. Human Mutation. 4: 42-50. PMID 7951257 DOI: 10.1002/Humu.1380040106 |
0.332 |
|
| 1994 |
Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB. Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 9936-40. PMID 7937921 DOI: 10.1073/Pnas.91.21.9936 |
0.689 |
|
| 1994 |
Westaway D, Zuliani V, Cooper CM, Da Costa M, Neuman S, Jenny AL, Detwiler L, Prusiner SB. Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie. Genes & Development. 8: 959-69. PMID 7926780 DOI: 10.1101/Gad.8.8.959 |
0.385 |
|
| 1994 |
Hsiao KK, Groth D, Scott M, Yang SL, Serban H, Rapp D, Foster D, Torchia M, Dearmond SJ, Prusiner SB. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 9126-30. PMID 7916462 DOI: 10.1073/Pnas.91.19.9126 |
0.425 |
|
| 1994 |
Prusiner SB. Molecular biology and genetics of prion diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 447-63. PMID 7913765 DOI: 10.1098/rstb.1994.0043 |
0.505 |
|
| 1994 |
DeArmond SJ, Yang SL, Cayetano-Canlas J, Groth D, Prusiner SB. The neuropathological phenotype in transgenic mice expressing different prion protein constructs. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 415-23. PMID 7913760 DOI: 10.1098/rstb.1994.0038 |
0.489 |
|
| 1994 |
Gabizon R, Rosenman H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB. Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 385-90. PMID 7913755 DOI: 10.1098/Rstb.1994.0033 |
0.323 |
|
| 1994 |
Carlson GA, DeArmond SJ, Torchia M, Westaway D, Prusiner SB. Genetics of prion diseases and prion diversity in mice. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 343: 363-9. PMID 7913753 DOI: 10.1098/rstb.1994.0030 |
0.482 |
|
| 1994 |
Huang Z, Gabriel JM, Baldwin MA, Fletterick RJ, Prusiner SB, Cohen FE. Proposed three-dimensional structure for the cellular prion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 7139-43. PMID 7913747 DOI: 10.1073/Pnas.91.15.7139 |
0.547 |
|
| 1994 |
Westaway D, Cooper C, Turner S, Da Costa M, Carlson GA, Prusiner SB. Structure and polymorphism of the mouse prion protein gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 6418-22. PMID 7912827 DOI: 10.1073/Pnas.91.14.6418 |
0.364 |
|
| 1994 |
Carlson GA, Ebeling C, Yang SL, Telling G, Torchia M, Groth D, Westaway D, DeArmond SJ, Prusiner SB. Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 5690-4. PMID 7911243 DOI: 10.1073/Pnas.91.12.5690 |
0.652 |
|
| 1994 |
Gomi H, Ikeda T, Kunieda T, Itohara S, Prusiner SB, Yamanouchi K. Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats. Neuroscience Letters. 166: 171-4. PMID 7909925 DOI: 10.1016/0304-3940(94)90478-2 |
0.321 |
|
| 1994 |
Cohen FE, Pan KM, Huang Z, Baldwin M, Fletterick RJ, Prusiner SB. Structural clues to prion replication. Science (New York, N.Y.). 264: 530-1. PMID 7909169 DOI: 10.1126/Science.7909169 |
0.488 |
|
| 1994 |
Prusiner SB. Biology and genetics of prion diseases. Annual Review of Microbiology. 48: 655-86. PMID 7826022 DOI: 10.1146/annurev.mi.48.100194.003255 |
0.494 |
|
| 1994 |
Prusiner SB, DeArmond SJ. Molecular biology and pathology of scrapie and the prion diseases of humans. Brain Pathology (Zurich, Switzerland). 1: 297-310. PMID 1669719 DOI: 10.1111/j.1750-3639.1991.tb00673.x |
0.475 |
|
| 1994 |
DeArmond S, Yang S, Carlson G, Prusiner S. The neuropathology of transgenic mice expressing prion protein constructs Journal of the Neurological Sciences. 127: 4. DOI: 10.1016/0022-510X(94)90113-9 |
0.405 |
|
| 1993 |
Rogers M, Yehiely F, Scott M, Prusiner SB. Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 3182-6. PMID 8475059 DOI: 10.1073/PNAS.90.8.3182 |
0.424 |
|
| 1993 |
Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R. Attempts to restore scrapie prion infectivity after exposure to protein denaturants Proceedings of the National Academy of Sciences of the United States of America. 90: 2793-2797. PMID 8464892 DOI: 10.1073/Pnas.90.7.2793 |
0.657 |
|
| 1993 |
Stahl N, Baldwin MA, Teplow DB, Hood L, Gibson BW, Burlingame AL, Prusiner SB. Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry. 32: 1991-2002. PMID 8448158 DOI: 10.1021/Bi00059A016 |
0.652 |
|
| 1993 |
Prusiner SB, Füzi M, Scott M, Serban D, Serban H, Taraboulos A, Gabriel JM, Wells GAH, Wilesmith JW, Bradley R, DeArmond SJ, Kristensson K. Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy Journal of Infectious Diseases. 167: 602-613. PMID 8440932 DOI: 10.1093/Infdis/167.3.602 |
0.437 |
|
| 1993 |
Gasset M, Baldwin MA, Fletterick RJ, Prusiner SB. Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity Proceedings of the National Academy of Sciences of the United States of America. 90: 1-5. PMID 8419912 DOI: 10.1073/Pnas.90.1.1 |
0.366 |
|
| 1993 |
Prusiner SB. Genetic and infectious prion diseases. Archives of Neurology. 50: 1129-53. PMID 8105771 DOI: 10.1001/ARCHNEUR.1993.00540110011002 |
0.524 |
|
| 1993 |
DeArmond SJ, Yang SL, Lee A, Bowler R, Taraboulos A, Groth D, Prusiner SB. Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 90: 6449-53. PMID 8101989 DOI: 10.1073/PNAS.90.14.6449 |
0.399 |
|
| 1993 |
Scott M, Groth D, Foster D, Torchia M, Yang SL, DeArmond SJ, Prusiner SB. Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes. Cell. 73: 979-88. PMID 8098995 DOI: 10.1016/0092-8674(93)90275-U |
0.434 |
|
| 1993 |
Prusiner SB. Transgenetic investigations of prion diseases of humans and animals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 339: 239-54. PMID 8097053 DOI: 10.1098/RSTB.1993.0022 |
0.457 |
|
| 1993 |
Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proceedings of the National Academy of Sciences of the United States of America. 90: 10608-12. PMID 7902565 DOI: 10.1073/Pnas.90.22.10608 |
0.407 |
|
| 1993 |
DeArmond SJ, Prusiner SB. The neurochemistry of prion diseases. Journal of Neurochemistry. 61: 1589-601. PMID 7901326 DOI: 10.1111/j.1471-4159.1993.tb09792.x |
0.38 |
|
| 1993 |
Borchelt DR, Rogers M, Stahl N, Telling G, Prusiner SB. Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology. 3: 319-29. PMID 7691278 DOI: 10.1093/Glycob/3.4.319 |
0.775 |
|
| 1993 |
Prusiner SB. Chemistry and biology of prions. Biochemistry. 31: 12277-88. PMID 1463717 DOI: 10.1021/BI00164A001 |
0.335 |
|
| 1993 |
Pan KM, Stahl N, Prusiner SB. Purification and properties of the cellular prion protein from Syrian hamster brain. Protein Science : a Publication of the Protein Society. 1: 1343-52. PMID 1363897 DOI: 10.1002/PRO.5560011014 |
0.363 |
|
| 1993 |
Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Corrections: Prion Protein Preamyloid and Amyloid Deposits in Gerstmann- Straussler-Scheinker Disease, Indiana Kindred Proceedings of the National Academy of Sciences of the United States of America. 90: 362. DOI: 10.1073/Pnas.90.1.362B |
0.415 |
|
| 1993 |
Baldwin MA, Pan K, Hecker R, Stahl N, Prusiner SB, Wang R, Chait BT. Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry of Membrane Proteins: The Scrapie Prion Protein Techniques in Protein Chemistry. 41-45. DOI: 10.1016/B978-0-12-058757-5.50009-3 |
0.627 |
|
| 1993 |
Baldwin MA, Burlingame AL, Prusiner SB. Mass spectrometric analysis of a GPI-anchored protein: The scrapie prion protein Trac Trends in Analytical Chemistry. 12: 239-248. DOI: 10.1016/0165-9936(93)87063-4 |
0.334 |
|
| 1992 |
Rogers M, Taraboulos A, Scott M, Groth D, Prusiner SB. Intracellular accumulation of the cellular prion protein after mutagenesis of its Asn-linked glycosylation sites. Glycobiology. 1: 101-9. PMID 1983782 DOI: 10.1093/GLYCOB/1.1.101 |
0.379 |
|
| 1992 |
Prusiner SB. Novel properties and biology of scrapie prions. Current Topics in Microbiology and Immunology. 172: 233-57. PMID 1687382 DOI: 10.1007/978-3-642-76540-7_14 |
0.303 |
|
| 1992 |
Stahl N, Baldwin MA, Prusiner SB. Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein. Cell Biology International Reports. 15: 853-62. PMID 1686992 DOI: 10.1016/0309-1651(91)90037-J |
0.613 |
|
| 1992 |
Hsiao K, Scott M, Foster D, DeArmond SJ, Groth D, Serban H, Prusiner SB. Spontaneous neurodegeneration in transgenic mice with prion protein codon 101 proline----leucine substitution. Annals of the New York Academy of Sciences. 640: 166-70. PMID 1685642 DOI: 10.1111/j.1749-6632.1991.tb00210.x |
0.456 |
|
| 1992 |
Prusiner SB. Molecular biology and transgenetics of prion diseases. Critical Reviews in Biochemistry and Molecular Biology. 26: 397-438. PMID 1684745 DOI: 10.3109/10409239109086789 |
0.371 |
|
| 1992 |
Hecker R, Taraboulos A, Scott M, Pan KM, Yang SL, Torchia M, Jendroska K, DeArmond SJ, Prusiner SB. Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters. Genes & Development. 6: 1213-28. PMID 1628828 DOI: 10.1101/GAD.6.7.1213 |
0.425 |
|
| 1992 |
Prusiner SB. Molecular biology and genetics of neurodegenerative diseases caused by prions. Advances in Virus Research. 41: 241-80. PMID 1575084 DOI: 10.1016/S0065-3527(08)60038-X |
0.386 |
|
| 1992 |
Gasset M, Baldwin MA, Lloyd DH, Gabriel JM, Holtzman DM, Cohen F, Fletterick R, Prusiner SB. Predicted α-helical regions of the prion protein when synthesized as peptides form amyloid Proceedings of the National Academy of Sciences of the United States of America. 89: 10940-10944. PMID 1438300 DOI: 10.1073/Pnas.89.22.10940 |
0.365 |
|
| 1992 |
Prusiner SB. Natural and experimental prion diseases of humans and animals. Current Opinion in Neurobiology. 2: 638-47. PMID 1422120 DOI: 10.1016/0959-4388(92)90032-G |
0.448 |
|
| 1992 |
Gabriel JM, Oesch B, Kretzschmar H, Scott M, Prusiner SB. Molecular cloning of a candidate chicken prion protein Proceedings of the National Academy of Sciences of the United States of America. 89: 9097-9101. PMID 1409608 DOI: 10.1073/PNAS.89.19.9097 |
0.563 |
|
| 1992 |
Kretzschmar HA, Neumann M, Riethmüller G, Prusiner SB. Molecular cloning of a mink prion protein gene. The Journal of General Virology. 2757-61. PMID 1383401 DOI: 10.1099/0022-1317-73-10-2757 |
0.6 |
|
| 1992 |
Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 356: 577-82. PMID 1373228 DOI: 10.1038/356577A0 |
0.409 |
|
| 1992 |
Hsiao K, Dlouhy SR, Farlow MR, Cass C, Da Costa M, Conneally PM, Hodes ME, Ghetti B, Prusiner SB. Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Nature Genetics. 1: 68-71. PMID 1363810 DOI: 10.1038/Ng0492-68 |
0.433 |
|
| 1992 |
Dlouhy SR, Hsiao K, Farlow MR, Foroud T, Conneally PM, Johnson P, Prusiner SB, Hodes ME, Ghetti B. Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene. Nature Genetics. 1: 64-7. PMID 1363809 DOI: 10.1038/Ng0492-64 |
0.407 |
|
| 1992 |
Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Proceedings of the National Academy of Sciences of the United States of America. 89: 9349-53. PMID 1357663 DOI: 10.1073/Pnas.89.19.9349 |
0.417 |
|
| 1992 |
Taraboulos A, Raeber AJ, Borchelt DR, Serban D, Prusiner SB. Synthesis and trafficking of prion proteins in cultured cells. Molecular Biology of the Cell. 3: 851-63. PMID 1356522 DOI: 10.1091/Mbc.3.8.851 |
0.583 |
|
| 1992 |
Raeber AJ, Borchelt DR, Scott M, Prusiner SB. Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems. Journal of Virology. 66: 6155-63. PMID 1356161 DOI: 10.1128/Jvi.66.10.6155-6163.1992 |
0.619 |
|
| 1992 |
Taraboulos A, Jendroska K, Serban D, Yang SL, DeArmond SJ, Prusiner SB. Regional mapping of prion proteins in brain. Proceedings of the National Academy of Sciences of the United States of America. 89: 7620-4. PMID 1354357 DOI: 10.1073/PNAS.89.16.7620 |
0.436 |
|
| 1992 |
Borchelt DR, Taraboulos A, Prusiner SB. Evidence for synthesis of scrapie prion proteins in the endocytic pathway. The Journal of Biological Chemistry. 267: 16188-99. PMID 1353761 |
0.551 |
|
| 1992 |
Meiner Z, Halimi M, Polakiewicz RD, Prusiner SB, Gabizon R. Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease. Neurology. 42: 1355-60. PMID 1352391 DOI: 10.1212/WNL.42.7.1355 |
0.429 |
|
| 1992 |
Stahl N, Baldwin MA, Hecker R, Pan KM, Burlingame AL, Prusiner SB. Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid. Biochemistry. 31: 5043-53. PMID 1350920 DOI: 10.1021/Bi00136A600 |
0.65 |
|
| 1992 |
Kretzschmar HA, Kufer P, Riethmüller G, DeArmond S, Prusiner SB, Schiffer D. Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome. Neurology. 42: 809-10. PMID 1348851 DOI: 10.1212/WNL.42.4.809 |
0.463 |
|
| 1992 |
Scott MR, Köhler R, Foster D, Prusiner SB. Chimeric prion protein expression in cultured cells and transgenic mice. Protein Science : a Publication of the Protein Society. 1: 986-97. PMID 1338978 DOI: 10.1002/pro.5560010804 |
0.404 |
|
| 1992 |
Dlouhy SR, Farlow M, Hsiao K, Foroud T, Johnson P, Conneally PM, Prusiner SB, Hodes ME, Ghetti B. Linkage of the indiana kindred variant of Gerstmann-Sträussler-Scheinker disease to a mutation in the prion protein gene (PRNP)☆ Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90402-J |
0.368 |
|
| 1992 |
Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Pathology, structural and biochemicalPrion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred☆ Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90282-3 |
0.399 |
|
| 1991 |
Hsiao K, Meiner Z, Kahana E, Cass C, Kahana I, Avrahami D, Scarlato G, Abramsky O, Prusiner SB, Gabizon R. Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease New England Journal of Medicine. 324: 1091-1097. PMID 2008182 DOI: 10.1056/NEJM199104183241604 |
0.377 |
|
| 1991 |
Epstein CJ, Foster DB, DeArmond SJ, Prusiner SB. Acceleration of scrapie in trisomy 16----diploid aggregation chimeras. Annals of Neurology. 29: 95-7. PMID 1996884 DOI: 10.1002/Ana.410290117 |
0.304 |
|
| 1991 |
Baldwin MA, Stahl N, Reinders LG, Gibson BW, Prusiner SB, Burlingame AL. Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein. Analytical Biochemistry. 191: 174-82. PMID 1981823 DOI: 10.1016/0003-2697(90)90405-X |
0.608 |
|
| 1991 |
Hsiao KK, Scott M, Foster D, Groth DF, DeArmond SJ, Prusiner SB. Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science (New York, N.Y.). 250: 1587-90. PMID 1980379 DOI: 10.1126/science.1980379 |
0.455 |
|
| 1991 |
Stahl N, Baldwin MA, Burlingame AL, Prusiner SB. Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein. Biochemistry. 29: 8879-84. PMID 1980209 DOI: 10.1021/Bi00490A001 |
0.631 |
|
| 1991 |
Stahl N, Prusiner SB. Prions and prion proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2799-807. PMID 1916104 DOI: 10.1096/Fasebj.5.13.1916104 |
0.676 |
|
| 1991 |
Carlson GA, Hsiao K, Oesch B, Westaway D, Prusiner SB. Genetics of prion infections. Trends in Genetics : Tig. 7: 61-5. PMID 1903568 DOI: 10.1016/0168-9525(91)90233-G |
0.405 |
|
| 1991 |
McKinley MP, Meyer RK, Kenaga L, Rahbar F, Cotter R, Serban A, Prusiner SB. Scrapie prion rod formation in vitro requires both detergent extraction and limited protenlysis Journal of Virology. 65: 1340-1351. PMID 1704926 DOI: 10.1128/JVI.65.3.1340-1351.1991 |
0.406 |
|
| 1991 |
Hsiao K, Prusiner SB. Molecular genetics and transgenic model of Gertsmann-Straussler-Scheinker disease Alzheimer Disease and Associated Disorders. 5: 155-162. PMID 1685324 DOI: 10.1097/00002093-199100530-00001 |
0.442 |
|
| 1991 |
Jendroska K, Heinzel FP, Torchia M, Stowring L, Kretzschmar HA, Kon A, Stern A, Prusiner SB, DeArmond SJ. Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity. Neurology. 41: 1482-90. PMID 1679911 DOI: 10.1212/WNL.41.9.1482 |
0.54 |
|
| 1991 |
Westaway D, Mirenda CA, Foster D, Zebarjadian Y, Scott M, Torchia M, Yang S, Serban H, DeArmond SJ, Ebeling C, Prusiner SB, Carlson GA. Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice Neuron. 7: 59-68. PMID 1676894 DOI: 10.1016/0896-6273(91)90074-A |
0.346 |
|
| 1991 |
Prusiner SB. Molecular biology of prion diseases. Science (New York, N.Y.). 252: 1515-22. PMID 1675487 DOI: 10.1126/science.1675487 |
0.474 |
|
| 1991 |
Hsiao KK, Cass C, Schellenberg GD, Bird T, Devine-Gage E, Wisniewski H, Prusiner SB. A prion protein variant in a family with the telencephalic form of Gerstmann-Sträussler-Scheinker syndrome. Neurology. 41: 681-4. PMID 1674116 DOI: 10.1212/Wnl.41.5.681 |
0.32 |
|
| 1991 |
Tagliavini F, Prelli F, Ghiso J, Bugiani O, Serban D, Prusiner SB, Farlow MR, Ghetti B, Frangione B. Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. The Embo Journal. 10: 513-9. PMID 1672107 DOI: 10.1002/J.1460-2075.1991.Tb07977.X |
0.468 |
|
| 1990 |
Scott M, Foster D, Mirenda C, Serban D, Coufal F, Wälchli M, Torchia M, Groth D, Carlson G, DeArmond SJ, Westaway D, Prusiner SB. Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell. 59: 847-57. PMID 2574076 DOI: 10.1016/0092-8674(89)90608-9 |
0.444 |
|
| 1990 |
Lowenstein DH, Butler DA, Westaway D, McKinley MP, DeArmond SJ, Prusiner SB. Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins. Molecular and Cellular Biology. 10: 1153-63. PMID 2406562 DOI: 10.1128/Mcb.10.3.1153 |
0.404 |
|
| 1990 |
Hsiao K, Prusiner SB. Inherited human prion diseases Neurology. 40: 1820-1827. PMID 2247227 DOI: 10.1212/WNL.40.12.1820 |
0.358 |
|
| 1990 |
McKinley MP, Longo FM, Valletta JS, Rahbar F, Neve RL, Prusiner SB, Mobley WC. Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system. Progress in Brain Research. 86: 227-38. PMID 1982367 DOI: 10.1016/S0079-6123(08)63180-5 |
0.343 |
|
| 1990 |
Taraboulos A, Rogers M, Borchelt DR, McKinley MP, Scott M, Serban D, Prusiner SB. Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 87: 8262-6. PMID 1978322 DOI: 10.1073/Pnas.87.21.8262 |
0.58 |
|
| 1990 |
Prusiner SB, Scott M, Foster D, Pan KM, Groth D, Mirenda C, Torchia M, Yang SL, Serban D, Carlson GA. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell. 63: 673-86. PMID 1977523 DOI: 10.1016/0092-8674(90)90134-Z |
0.452 |
|
| 1990 |
Oesch B, Teplow DB, Stahl N, Serban D, Hood LE, Prusiner SB. Identification of cellular proteins binding to the scrapie prion protein. Biochemistry. 29: 5848-55. PMID 1974464 DOI: 10.1021/Bi00476A029 |
0.693 |
|
| 1990 |
Stahl N, Borchelt DR, Prusiner SB. Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. Biochemistry. 29: 5405-12. PMID 1974460 DOI: 10.1021/Bi00474A028 |
0.728 |
|
| 1990 |
Lopez CD, Yost CS, Prusiner SB, Myers RM, Lingappa VR. Unusual topogenic sequence directs prion protein biogenesis. Science (New York, N.Y.). 248: 226-9. PMID 1970195 DOI: 10.1126/Science.1970195 |
0.337 |
|
| 1990 |
Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB. Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. The Journal of Cell Biology. 110: 743-52. PMID 1968466 DOI: 10.1083/Jcb.110.3.743 |
0.598 |
|
| 1990 |
Yost CS, Lopez CD, Prusiner SB, Myers RM, Lingappa VR. Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein. Nature. 343: 669-72. PMID 1968226 DOI: 10.1038/343669A0 |
0.321 |
|
| 1990 |
Serban D, Taraboulos A, DeArmond SJ, Prusiner SB. Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins. Neurology. 40: 110-7. PMID 1967489 DOI: 10.1212/WNL.40.1.110 |
0.457 |
|
| 1990 |
Taraboulos A, Serban D, Prusiner SB. Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells. The Journal of Cell Biology. 110: 2117-32. PMID 1693623 DOI: 10.1083/JCB.110.6.2117 |
0.383 |
|
| 1990 |
Scott M, Foster D, Mirenda C, Serban D, Coufal F, Wälchli M, Torchia M, Groth D, Carlson G, DeArmond SJ, Westaway D, Prusiner SB. TRANSGENIC MICE EXPRESSING HAMSTER PRION PROTEIN PRODUCE SPECIES -SPECIFIC SCRAPIE INFECTIVITY AND AMYLOID PLAQUES Journal of Neuropathology and Experimental Neurology. 49: 311. DOI: 10.1097/00005072-199005000-00158 |
0.417 |
|
| 1990 |
Taraboulos A, Serban D, Prusiner SB. IN SITU IDENTIFICATION OF SCRAPIE PRION PROTEINS IN THE CYTOPLASM OF PERSISTENTLY-INFECTED CULTURED CELLS Journal of Neuropathology and Experimental Neurology. 49: 311. DOI: 10.1097/00005072-199005000-00157 |
0.348 |
|
| 1990 |
Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB. Scrapie And Cellular Prion Proteins Differ In Their Kinetics Of Synthesis And Topology In Cultured Cells: 150 Journal of Neuropathology and Experimental Neurology. 49: 311. DOI: 10.1097/00005072-199005000-00156 |
0.56 |
|
| 1990 |
Serban D, Taraboulos A, DeArmond SJ, Prusiner SB. RAPID DETECTION OF CREUTZFELDT-JAKOB DISEASE AND SCRAPIE PRION PROTEINS Journal of Neuropathology and Experimental Neurology. 49: 290. DOI: 10.1097/00005072-199005000-00094 |
0.401 |
|
| 1990 |
BALDWIN M, STAHL N, BURLINGAME A, PRUSINER S. Structure determination of glycoinositol phospholipid anchors by permethylation and tandem mass spectrometry Methods. 1: 306-314. DOI: 10.1016/S1046-2023(05)80332-9 |
0.585 |
|
| 1990 |
Baldwin MA, Falick AM, Gibson BW, Prusiner SB, Stahl N, Burlingame AL. Tandem mass spectrometry of peptides with N-terminal glutamine studies on a prion protein peptide Journal of the American Society For Mass Spectrometry. 1: 258-264. DOI: 10.1016/1044-0305(90)85043-L |
0.597 |
|
| 1989 |
Bazan JF, Fletterick RJ, McKinley MP, Prusiner SB. Predicted secondary structure and membrane topology of the scrapie prion protein. Protein Engineering. 1: 125-35. PMID 2907134 DOI: 10.1093/Protein/1.2.125 |
0.431 |
|
| 1989 |
Prusiner SB. Molecular structure, biology, and genetics of prions. Advances in Virus Research. 35: 83-136. PMID 2906782 DOI: 10.1016/S0065-3527(08)60709-5 |
0.383 |
|
| 1989 |
Carlson GA, Westaway D, DeArmond SJ, Peterson-Torchia M, Prusiner SB. Primary structure of prion protein may modify scrapie isolate properties. Proceedings of the National Academy of Sciences of the United States of America. 86: 7475-9. PMID 2798418 DOI: 10.1073/PNAS.86.19.7475 |
0.404 |
|
| 1989 |
Prusiner SB. Scrapie prions. Annual Review of Microbiology. 43: 345-74. PMID 2572197 DOI: 10.1146/annurev.mi.43.100189.002021 |
0.329 |
|
| 1989 |
Prusiner SB. Creutzfeldt-Jakob disease and scrapie prions. Alzheimer Disease and Associated Disorders. 3: 52-78. PMID 2568118 DOI: 10.1097/00002093-198903010-00007 |
0.476 |
|
| 1989 |
Hsiao K, Baker HF, Crow TJ, Poulter M, Owen F, Terwilliger JD, Westaway D, Ott J, Prusiner SB. Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature. 338: 342-5. PMID 2564168 DOI: 10.1038/338342A0 |
0.393 |
|
| 1989 |
Owen F, Poulter M, Lofthouse R, Collinge J, Crow TJ, Risby D, Baker HF, Ridley RM, Hsiao K, Prusiner SB. Insertion in prion protein gene in familial Creutzfeldt-Jakob disease. Lancet. 1: 51-2. PMID 2563037 DOI: 10.1016/S0140-6736(89)91713-3 |
0.359 |
|
| 1989 |
Snow AD, Kisilevsky R, Willmer J, Prusiner SB, DeArmond SJ. Sulfated glycosaminoglycans in amyloid plaques of prion diseases. Acta Neuropathologica. 77: 337-42. PMID 2523631 DOI: 10.1007/BF00687367 |
0.376 |
|
| 1989 |
McKinley MP, DeArmond SJ, Torchia M, Mobley WC, Prusiner SB. Acceleration of scrapie in neonatal Syrian hamsters. Neurology. 39: 1319-24. PMID 2507957 DOI: 10.1212/Wnl.39.10.1319 |
0.349 |
|
| 1989 |
Westaway D, Carlson GA, Prusiner SB. Unraveling prion diseases through molecular genetics Trends in Neurosciences. 12: 221-227. PMID 2473558 DOI: 10.1016/0166-2236(89)90126-4 |
0.43 |
|
| 1988 |
Prusiner SB. Prions and neurodegenerative diseases. The New England Journal of Medicine. 317: 1571-81. PMID 3317055 DOI: 10.1056/NEJM198712173172505 |
0.361 |
|
| 1988 |
Butler DA, Scott MR, Bockman JM, Borchelt DR, Taraboulos A, Hsiao KK, Kingsbury DT, Prusiner SB. Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. Journal of Virology. 62: 1558-64. PMID 3282080 DOI: 10.1128/Jvi.62.5.1558-1564.1988 |
0.634 |
|
| 1988 |
Carlson GA, Goodman PA, Lovett M, Taylor BA, Marshall ST, Peterson-Torchia M, Westaway D, Prusiner SB. Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time. Molecular and Cellular Biology. 8: 5528-40. PMID 3149717 DOI: 10.1128/MCB.8.12.5528 |
0.335 |
|
| 1988 |
Turk E, Teplow DB, Hood LE, Prusiner SB. Purification and properties of the cellular and scrapie hamster prion proteins. European Journal of Biochemistry / Febs. 176: 21-30. PMID 3138115 DOI: 10.1111/J.1432-1033.1988.Tb14246.X |
0.394 |
|
| 1988 |
Gabizon R, McKinley MP, Groth D, Prusiner SB. Immunoaffinity purification and neutralization of scrapie prion infectivity. Proceedings of the National Academy of Sciences of the United States of America. 85: 6617-21. PMID 3137571 DOI: 10.1073/PNAS.85.18.6617 |
0.416 |
|
| 1988 |
Bellinger-Kawahara CG, Kempner E, Groth D, Gabizon R, Prusiner SB. Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da. Virology. 164: 537-41. PMID 3130718 DOI: 10.1016/0042-6822(88)90569-7 |
0.399 |
|
| 1988 |
Scott MR, Butler DA, Bredesen DE, Wälchli M, Hsiao KK, Prusiner SB. Prion protein gene expression in cultured cells. Protein Engineering. 2: 69-76. PMID 2908139 DOI: 10.1093/PROTEIN/2.1.69 |
0.395 |
|
| 1988 |
Mobley WC, Neve RL, Prusiner SB, McKinley MP. Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain. Proceedings of the National Academy of Sciences of the United States of America. 85: 9811-5. PMID 2904679 DOI: 10.1073/Pnas.85.24.9811 |
0.344 |
|
| 1988 |
Roberts GW, Lofthouse R, Allsop D, Landon M, Kidd M, Prusiner SB, Crow TJ. CNS amyloid proteins in neurodegenerative diseases. Neurology. 38: 1534-40. PMID 2901696 DOI: 10.1212/WNL.38.10.1534 |
0.414 |
|
| 1988 |
Prusiner SB, Stahl N, DeArmond SJ. Novel mechanisms of degeneration of the central nervous system--prion structure and biology. Ciba Foundation Symposium. 135: 239-60. PMID 2900720 DOI: 10.1002/9780470513613.CH16 |
0.382 |
|
| 1988 |
Gabizon R, McKinley MP, Prusiner SB. Properties of scrapie prion proteins in liposomes and amyloid rods. Ciba Foundation Symposium. 135: 182-96. PMID 2900719 DOI: 10.1002/9780470513613.CH12 |
0.318 |
|
| 1988 |
CARLSON GA, WESTAWAY D, PRUSINER SB. THE MOUSE PRION GENE COMPLEX AND SUSCEPTIBILITY TO TRANSMISSIBLE NEURODEGENERATIVE DISEASES Alzheimer Disease & Associated Disorders. 2: 302. DOI: 10.1097/00002093-198802030-00151 |
0.36 |
|
| 1988 |
PRUSINER SB, GABIZON R, GROTH DF, McKINLEY MP. IMMUNOAFFINITY PURIFICATION AND NEUTRALIZATION OF SCRAPIE PRIONS Alzheimer Disease & Associated Disorders. 2: 300. DOI: 10.1097/00002093-198802030-00149 |
0.375 |
|
| 1988 |
Westaway D, Goodman PA, Mirenda CA, McKinley MP, Carlson GA, Prusiner SB. Distinct prion proteins in short and long scrapie incubation period mice Cell. 53: 651-662. DOI: 10.1016/0092-8674(87)90134-6 |
0.383 |
|
| 1987 |
Hogan RN, Baringer JR, Prusiner SB. Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis. Journal of Neuropathology and Experimental Neurology. 46: 461-73. PMID 3598605 DOI: 10.1097/00005072-198707000-00005 |
0.313 |
|
| 1987 |
McKinley MP, Hay B, Lingappa VR, Lieberburg I, Prusiner SB. Developmental expression of prion protein gene in brain. Developmental Biology. 121: 105-10. PMID 3569656 DOI: 10.1016/0012-1606(87)90143-6 |
0.325 |
|
| 1987 |
Prusiner SB. Prions causing degenerative neurological diseases. Annual Review of Medicine. 38: 381-98. PMID 3555303 DOI: 10.1146/ANNUREV.ME.38.020187.002121 |
0.392 |
|
| 1987 |
Prusiner SB, Gabizon R, McKinley MP. On the biology of prions. Acta Neuropathologica. 72: 299-314. PMID 3554880 DOI: 10.1007/BF00687261 |
0.482 |
|
| 1987 |
Prusiner SB. Prions are novel infectious pathogens causing scrapie and Creutzfeldt-Jakob disease. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 5: 281-6. PMID 3551942 DOI: 10.1002/BIES.950050612 |
0.473 |
|
| 1987 |
Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR. Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]. Molecular and Cellular Biology. 7: 914-20. PMID 3547085 DOI: 10.1128/Mcb.7.2.914 |
0.4 |
|
| 1987 |
Bockman JM, Prusiner SB, Tateishi J, Kingsbury DT. Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes. Annals of Neurology. 21: 589-95. PMID 3300520 DOI: 10.1002/ANA.410210611 |
0.449 |
|
| 1987 |
Hay B, Prusiner SB, Lingappa VR. Evidence for a secretory form of the cellular prion protein. Biochemistry. 26: 8110-5. PMID 3126796 DOI: 10.1021/Bi00399A014 |
0.395 |
|
| 1987 |
Bellinger-Kawahara C, Diener TO, McKinley MP, Groth DF, Smith DR, Prusiner SB. Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids. Virology. 160: 271-4. PMID 3114950 DOI: 10.1016/0042-6822(87)90072-9 |
0.311 |
|
| 1987 |
DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB. Changes in the localization of brain prion proteins during scrapie infection. Neurology. 37: 1271-80. PMID 3112607 DOI: 10.1212/Wnl.37.8.1271 |
0.41 |
|
| 1987 |
Gabizon R, McKinley MP, Prusiner SB. Purified prion proteins and scrapie infectivity copartition into liposomes. Proceedings of the National Academy of Sciences of the United States of America. 84: 4017-21. PMID 3108886 DOI: 10.1073/PNAS.84.12.4017 |
0.424 |
|
| 1987 |
Stahl N, Borchelt DR, Hsiao K, Prusiner SB. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell. 51: 229-40. PMID 2444340 DOI: 10.1016/0092-8674(87)90150-4 |
0.733 |
|
| 1986 |
Kretzschmar HA, Stowring LE, Westaway D, Stubblebine WH, Prusiner SB, Dearmond SJ. Molecular cloning of a human prion protein cDNA. Dna (Mary Ann Liebert, Inc.). 5: 315-24. PMID 3755672 DOI: 10.1089/DNA.1986.5.315 |
0.497 |
|
| 1986 |
McKinley MP, Prusiner SB. Biology and structure of scrapie prions International Review of Neurobiology. 28: 1-57. PMID 3100471 DOI: 10.1016/S0074-7742(08)60105-1 |
0.372 |
|
| 1986 |
Kitamoto T, Tateishi J, Tashima T, Takeshita I, Barry RA, DeArmond SJ, Prusiner SB. Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies. Annals of Neurology. 20: 204-8. PMID 3092727 DOI: 10.1002/ana.410200205 |
0.431 |
|
| 1986 |
Barry RA, Prusiner SB. Monoclonal antibodies to the cellular and scrapie prion proteins. The Journal of Infectious Diseases. 154: 518-21. PMID 3090160 DOI: 10.1093/infdis/154.3.518 |
0.415 |
|
| 1986 |
Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA, Prusiner SB. Separation and properties of cellular and scrapie prion proteins. Proceedings of the National Academy of Sciences of the United States of America. 83: 2310-4. PMID 3085093 DOI: 10.1073/PNAS.83.8.2310 |
0.413 |
|
| 1986 |
Carlson GA, Kingsbury DT, Goodman PA, Coleman S, Marshall ST, DeArmond S, Westaway D, Prusiner SB. Linkage of prion protein and scrapie incubation time genes Cell. 46: 503-511. PMID 3015416 DOI: 10.1016/0092-8674(86)90875-5 |
0.358 |
|
| 1986 |
Prusiner SB. Scrapie prions, brain amyloid, and senile dementia. Current Topics in Cellular Regulation. 26: 79-95. PMID 2934227 DOI: 10.1016/B978-0-12-152826-3.50014-0 |
0.33 |
|
| 1986 |
Basler K, Oesch B, Scott M, Westaway D, Wälchli M, Groth DF, McKinley MP, Prusiner SB, Weissmann C. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell. 46: 417-28. PMID 2873895 DOI: 10.1016/0092-8674(86)90662-8 |
0.358 |
|
| 1986 |
McKinley MP, Braunfeld MB, Bellinger CG, Prusiner SB. Molecular characteristics of prion rods purified from scrapie-infected hamster brains. The Journal of Infectious Diseases. 154: 110-20. PMID 2872252 DOI: 10.1093/INFDIS/154.1.110 |
0.353 |
|
| 1986 |
Westaway D, Prusiner SB. Conservation of the cellular gene encoding the scrapie prion protein. Nucleic Acids Research. 14: 2035-44. PMID 2870469 DOI: 10.1093/NAR/14.5.2035 |
0.339 |
|
| 1986 |
Barry RA, Kent SB, McKinley MP, Meyer RK, DeArmond SJ, Hood LE, Prusiner SB. Scrapie and cellular prion proteins share polypeptide epitopes. The Journal of Infectious Diseases. 153: 848-54. PMID 2422294 DOI: 10.1093/Infdis/153.5.848 |
0.44 |
|
| 1986 |
Wiley CA, Burrola PG, Buchmeier MJ, Wooddell MK, Barry RA, Prusiner SB, Lampert PW. IMMUNO-GOLD LABELING OF FILAMENTOUS STRUCTURES ANTIGENICALLY RELATED TO THE PRION PROTEIN WITH SCRAPIE INFECTED HAMSTER BRAINS Journal of Neuropathology and Experimental Neurology. 45: 336. DOI: 10.1097/00005072-198605000-00068 |
0.363 |
|
| 1986 |
DeArmond S, Kretzschmar H, McKinley M, Barry R, Meyer R, Westaway D, Prusiner S. CHEMICAL AND BIOLOGICAL PROPERTIES OF THE PRION PROTEIN AND ITS CELLULAR ISOFORM Journal of Neuropathology and Experimental Neurology. 45: 329. DOI: 10.1097/00005072-198605000-00048 |
0.516 |
|
| 1985 |
Bolton DC, McKinley MP, Prusiner SB. Molecular characteristics of the major scrapie prion protein. Biochemistry. 23: 5898-906. PMID 6395885 DOI: 10.1021/BI00320A002 |
0.435 |
|
| 1985 |
Prusiner SB. Prions: novel infectious pathogens. Advances in Virus Research. 29: 1-56. PMID 6241423 DOI: 10.1016/S0065-3527(08)60404-2 |
0.378 |
|
| 1985 |
Prusiner SB, Cochran SP, Alpers MP. Transmission of scrapie in hamsters. The Journal of Infectious Diseases. 152: 971-8. PMID 3930630 DOI: 10.1093/INFDIS/152.5.971 |
0.333 |
|
| 1985 |
Bolton DC, Meyer RK, Prusiner SB. Scrapie PrP 27-30 is a sialoglycoprotein Journal of Virology. 53: 596-606. PMID 3918176 DOI: 10.1128/JVI.53.2.596-606.1985 |
0.376 |
|
| 1985 |
Bockman JM, Kingsbury DT, McKinley MP, Bendheim PE, Prusiner SB. Creutzfeldt-Jakob disease prion proteins in human brains. The New England Journal of Medicine. 312: 73-8. PMID 3917302 DOI: 10.1056/NEJM198501103120202 |
0.444 |
|
| 1985 |
Bendheim PE, Bockman JM, McKinley MP, Kingsbury DT, Prusiner SB. Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants. Proceedings of the National Academy of Sciences of the United States of America. 82: 997-1001. PMID 2579394 DOI: 10.1073/PNAS.82.4.997 |
0.42 |
|
| 1985 |
DeArmond SJ, Kretzschtnar HA, McKinley MP, Barry RA, Braunfeld HB, Prusiner SB. IDENTIFICATION OF PRION AMYLOID FILAMENTS IN SCRAPIE-INFECTED BRAIN Journal of Neuropathology and Experimental Neurology. 44: 364. DOI: 10.1097/00005072-198505000-00179 |
0.352 |
|
| 1985 |
Prusiner S, Barry R, Bellinger C, Bendheim P, Bolton D, Bowman K, Braunfeld M, Cochran P, DeArmand S, Espanol E, Groth D, Hennessey E, May T, Meyer R, McKinley M. Abstract 2. Prion diseases Progress in Neuro-Psychopharmacology & Biological Psychiatry. 9: 295. DOI: 10.1016/0278-5846(85)90097-1 |
0.379 |
|
| 1984 |
Prusiner SB, Groth DF, Bolton DC, Kent SB, Hood LE. Purification and structural studies of a major scrapie prion protein Cell. 38: 127-134. PMID 6432339 DOI: 10.1016/0092-8674(84)90533-6 |
0.361 |
|
| 1984 |
Bendheim PE, Barry RA, DeArmond SJ, Stites DP, Prusiner SB. Antibodies to a scrapie prion protein. Nature. 310: 418-21. PMID 6431296 DOI: 10.1038/310418a0 |
0.431 |
|
| 1984 |
Prusiner SB. Some speculations about prions, amyloid, and Alzheimer's disease. The New England Journal of Medicine. 310: 661-3. PMID 6363926 DOI: 10.1056/NEJM198403083101021 |
0.376 |
|
| 1983 |
Bolton DC, McKinley MP, Prusiner SB. Identification of a protein that purifies with the scrapie prion. Science (New York, N.Y.). 218: 1309-11. PMID 6815801 DOI: 10.1126/SCIENCE.6815801 |
0.378 |
|
| 1983 |
Prusiner SB, McKinley MP, Bowman KA, Bolton DC, Bendheim PE, Groth DF, Glenner GG. Scrapie prions aggregate to form amyloid-like birefringent rods. Cell. 35: 349-58. PMID 6418385 DOI: 10.1016/0092-8674(83)90168-X |
0.418 |
|
| 1983 |
McKinley MP, Bolton DC, Prusiner SB. A protease-resistant protein is a structural component of the scrapie prion. Cell. 35: 57-62. PMID 6414721 DOI: 10.1016/0092-8674(83)90207-6 |
0.456 |
|
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