| Year |
Citation |
Score |
| 2024 |
Xu M, Neelands T, Powers AS, Liu Y, Miller SD, Pintilie GD, Bois JD, Dror RO, Chiu W, Maduke M. CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife. 12. PMID 38345841 DOI: 10.7554/eLife.90648 |
0.461 |
|
| 2023 |
Xu M, Neelands T, Powers AS, Liu Y, Miller SD, Pintilie G, Du Bois J, Dror RO, Chiu W, Maduke M. CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism. Biorxiv : the Preprint Server For Biology. PMID 37645939 DOI: 10.1101/2023.08.13.553136 |
0.468 |
|
| 2020 |
Koster AK, Reese AL, Kuryshev Y, Wen X, McKiernan KA, Gray EE, Wu C, Huguenard JR, Maduke M, Du Bois J. Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 33277431 DOI: 10.1073/pnas.2009977117 |
0.398 |
|
| 2020 |
Lahey LJ, Mardjuki RE, Wen X, Hess GT, Ritchie C, Carozza JA, Böhnert V, Maduke M, Bassik MC, Li L. LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP. Molecular Cell. PMID 33171122 DOI: 10.1016/j.molcel.2020.10.021 |
0.393 |
|
| 2020 |
Cheng RC, Maduke M. Expanding the membrane-protein NMR toolkit. Nature Chemical Biology. PMID 32665639 DOI: 10.1038/S41589-020-0597-7 |
0.334 |
|
| 2020 |
McKiernan KA, Koster AK, Maduke M, Pande VS. Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating. Plos Computational Biology. 16: e1007530. PMID 32226009 DOI: 10.1371/Journal.Pcbi.1007530 |
0.517 |
|
| 2020 |
Chavan TS, Cheng RC, Jiang T, Mathews II, Stein RA, Koehl A, Mchaourab HS, Tajkhorshid E, Maduke M. Author response: A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle Elife. DOI: 10.7554/Elife.53479.Sa2 |
0.314 |
|
| 2020 |
Chavan T, Cheng R, Jiang T, Mathews II, Stein RA, Koehl A, Krishnamoorti A, Durham RJ, Berka V, Mchaourab H, Tajkhorshid E, Jayaraman V, Maduke M. Investigating Conformational Changes to Understand the Transport Mechanism of CLC Chloride/Proton Antiporters Biophysical Journal. 118: 443a. DOI: 10.1016/J.Bpj.2019.11.2481 |
0.348 |
|
| 2019 |
Maduke M, Delemotte L. Decision letter: Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state Elife. DOI: 10.7554/Elife.53901.Sa1 |
0.416 |
|
| 2019 |
Islas LD, Pusch M, Maduke M. Decision letter: Divergent Cl- and H+ pathways underlie transport coupling and gating in CLC exchangers and channels Elife. DOI: 10.7554/Elife.51224.Sa1 |
0.436 |
|
| 2018 |
Koster AK, Wood CAP, Thomas-Tran R, Chavan TS, Almqvist J, Choi KH, Du Bois J, Maduke M. A selective class of inhibitors for the CLC-Ka chloride ion channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 29669921 DOI: 10.1073/Pnas.1720584115 |
0.489 |
|
| 2018 |
Prieto ML, Firouzi K, Khuri-Yakub BT, Maduke M. Activation of Piezo1 but Not Na1.2 Channels by Ultrasound at 43 MHz. Ultrasound in Medicine & Biology. PMID 29525457 DOI: 10.1016/J.Ultrasmedbio.2017.12.020 |
0.496 |
|
| 2018 |
Prieto ML, Madison DV, Khuri-Yakub BT, Maduke M. Focused Ultrasound Activates Task Potassium Channels, Increases Membrane Capacitance, and Modulates Action Potential Waveform and Firing Properties in Hippocampal Brain Slices Biophysical Journal. 114: 669a. DOI: 10.1016/J.Bpj.2017.11.3609 |
0.384 |
|
| 2017 |
Chavan T, Maduke M, Swartz K. Protein ligands for studying ion channel proteins. The Journal of General Physiology. PMID 28270405 DOI: 10.1085/Jgp.201711776 |
0.457 |
|
| 2017 |
Koster AK, Wood C, Thomas-Tran R, Chavan TS, Almqvist J, Choi K, Du Bois J, Maduke M. Developing a Novel Class of CLC Chloride-Channel Inhibitors Biophysical Journal. 112: 339a. DOI: 10.1016/J.Bpj.2016.11.1836 |
0.439 |
|
| 2017 |
Maduke M. CLC Chloride/Proton Transporters Biophysical Journal. 112: 308a. DOI: 10.1016/J.Bpj.2016.11.1666 |
0.334 |
|
| 2016 |
Jiang T, Han W, Maduke M, Tajkhorshid E. Molecular Basis for Differential Anion Binding and Proton Coupling in the Cl(-)/H(+) Exchanger ClC-ec1. Journal of the American Chemical Society. PMID 26880377 DOI: 10.1021/Jacs.5B12062 |
0.352 |
|
| 2016 |
Khantwal CM, Abraham SJ, Han W, Jiang T, Chavan TS, Cheng RC, Elvington SM, Liu CW, Mathews II, Stein RA, Mchaourab HS, Tajkhorshid E, Maduke M. Revealing an outward-facing open conformational state in a CLC Cl(-)/H(+) exchange transporter. Elife. 5. PMID 26799336 DOI: 10.7554/Elife.11189 |
0.409 |
|
| 2016 |
Khantwal CM, Abraham SJ, Han W, Jiang T, Chavan TS, Cheng RC, Elvington SM, Liu CW, Mathews II, Stein RA, Mchaourab HS, Tajkhorshid E, Maduke M. Author response: Revealing an outward-facing open conformational state in a CLC Cl–/H+ exchange transporter Elife. DOI: 10.7554/Elife.11189.031 |
0.322 |
|
| 2016 |
Abraham SJ, Chavan T, Cheng RC, Fenollar-Ferrer C, Han W, Islam SM, Jiang T, Khantwal CM, Mathews II, Stein RA, Roux B, Forrest LR, Mchaourab HS, Tajkhorshid E, Maduke M. An Outward-Facing Open Conformational State in a CLC Transporter Biophysical Journal. 110: 178a. DOI: 10.1016/J.Bpj.2015.11.994 |
0.403 |
|
| 2015 |
Abraham SJ, Cheng RC, Chew TA, Khantwal CM, Liu CW, Gong S, Nakamoto RK, Maduke M. 13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1. Journal of Biomolecular Nmr. 61: 209-26. PMID 25631353 DOI: 10.1007/S10858-015-9898-7 |
0.387 |
|
| 2013 |
Denton JS, Pao AC, Maduke M. Novel diuretic targets. American Journal of Physiology. Renal Physiology. 305: F931-42. PMID 23863472 DOI: 10.1152/Ajprenal.00230.2013 |
0.426 |
|
| 2012 |
Howery AE, Elvington S, Abraham SJ, Choi KH, Dworschak-Simpson S, Phillips S, Ryan CM, Sanford RL, Almqvist J, Tran K, Chew TA, Zachariae U, Andersen OS, Whitelegge J, Matulef K, ... ... Maduke MC, et al. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chemistry & Biology. 19: 1460-70. PMID 23177200 DOI: 10.1016/J.Chembiol.2012.09.017 |
0.438 |
|
| 2012 |
Matulef KI, Howery A, Sanford RL, Phillips S, Simpson S, Abraham S, Whitelegge J, Du Bois J, Andersen OS, Maduke M. Characterization of a Novel CLC-ec1 Inhibitor Biophysical Journal. 102: 520a. DOI: 10.1016/J.Bpj.2011.11.2845 |
0.398 |
|
| 2012 |
Maduke M. CLC Transporters: The Search for Conformational Change Biophysical Journal. 102: 407a. DOI: 10.1016/J.Bpj.2011.11.2226 |
0.359 |
|
| 2010 |
Howery AE, Almqvist J, Du Bois J, Maduke M. Towards Identifying the Structural Basis For Inhibition By a Newly Discovered Class of CLC Chloride-Channel Inhibitors Biophysical Journal. 98: 35a. DOI: 10.1016/J.Bpj.2009.12.206 |
0.461 |
|
| 2009 |
Lísal J, Maduke M. Review. Proton-coupled gating in chloride channels. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 181-7. PMID 18957380 DOI: 10.1098/Rstb.2008.0123 |
0.537 |
|
| 2009 |
Elvington S, Liu C, Maduke M. Fluorine-NMR Reveals Conformational Differences Between ClC-ec1 Operating In Transporter And “Channel-like” Modes Biophysical Journal. 96: 471a. DOI: 10.1016/J.Bpj.2008.12.2424 |
0.474 |
|
| 2008 |
Elvington SM, Maduke M. Thinking outside the crystal: complementary approaches for examining transporter conformational change. Channels (Austin, Tex.). 2: 373-9. PMID 18989097 DOI: 10.4161/Chan.2.5.6903 |
0.378 |
|
| 2008 |
Holmqvist M, Maduke M. Ion channel targets - select biosciences' fourth annual conference. Idrugs : the Investigational Drugs Journal. 11: 795-8. PMID 18988121 |
0.308 |
|
| 2008 |
Martinez GQ, Maduke M. A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane. Plos One. 3: e2746. PMID 18648499 DOI: 10.1371/journal.pone.0002746 |
0.719 |
|
| 2008 |
Matulef K, Howery AE, Tan L, Kobertz WR, Du Bois J, Maduke M. Discovery of potent CLC chloride channel inhibitors. Acs Chemical Biology. 3: 419-28. PMID 18642799 DOI: 10.1021/Cb800083A |
0.67 |
|
| 2008 |
Lísal J, Maduke M. The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter. Nature Structural & Molecular Biology. 15: 805-10. PMID 18641661 DOI: 10.1038/Nsmb.1466 |
0.529 |
|
| 2007 |
Engh AM, Faraldo-Gómez JD, Maduke M. The role of a conserved lysine in chloride- and voltage-dependent ClC-0 fast gating. The Journal of General Physiology. 130: 351-63. PMID 17846165 DOI: 10.1085/Jgp.200709760 |
0.728 |
|
| 2007 |
Engh AM, Faraldo-Gómez JD, Maduke M. The mechanism of fast-gate opening in ClC-0. The Journal of General Physiology. 130: 335-49. PMID 17846164 DOI: 10.1085/Jgp.200709759 |
0.734 |
|
| 2007 |
Matulef K, Maduke M. The CLC 'chloride channel' family: revelations from prokaryotes. Molecular Membrane Biology. 24: 342-50. PMID 17710638 DOI: 10.1080/09687680701413874 |
0.536 |
|
| 2005 |
Matulef K, Maduke M. Side-dependent inhibition of a prokaryotic ClC by DIDS. Biophysical Journal. 89: 1721-30. PMID 15994902 DOI: 10.1529/Biophysj.105.066522 |
0.428 |
|
| 2005 |
Engh AM, Maduke M. Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule. The Journal of General Physiology. 125: 601-17. PMID 15897295 DOI: 10.1085/Jgp.200509258 |
0.746 |
|
| 2003 |
Maduke M, Mindell JA. The poststructural festivities begin. Neuron. 38: 1-3. PMID 12691656 DOI: 10.1016/S0896-6273(03)00204-6 |
0.603 |
|
| 2001 |
Mindell JA, Maduke M, Miller C, Grigorieff N. Projection structure of a ClC-type chloride channel at 6.5 A resolution. Nature. 409: 219-23. PMID 11196649 DOI: 10.1038/35051631 |
0.702 |
|
| 2001 |
Mindell JA, Maduke M. ClC chloride channels. Genome Biology. 2: REVIEWS3003. PMID 11182894 DOI: 10.1186/Gb-2001-2-2-Reviews3003 |
0.672 |
|
| 2000 |
Maduke M, Miller C, Mindell JA. A decade of CLC chloride channels: structure, mechanism, and many unsettled questions. Annual Review of Biophysics and Biomolecular Structure. 29: 411-38. PMID 10940254 DOI: 10.1146/Annurev.Biophys.29.1.411 |
0.695 |
|
| 1999 |
Maduke M, Pheasant DJ, Miller C. High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. The Journal of General Physiology. 114: 713-22. PMID 10539975 DOI: 10.1085/Jgp.114.5.713 |
0.586 |
|
| 1998 |
Maduke M, Williams C, Miller C. Formation of CLC-0 chloride channels from separated transmembrane and cytoplasmic domains. Biochemistry. 37: 1315-21. PMID 9477958 DOI: 10.1021/Bi972418O |
0.553 |
|
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