| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2019 | Liu Q, Johnson EM, Lam RK, Wang Q, Bo Ye H, Wilson EN, Minhas PS, Liu L, Swarovski MS, Tran S, Wang J, Mehta SS, Yang X, Rabinowitz JD, Yang SS, ... Shamloo M, et al. Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity. Nature Immunology. PMID 31263278 DOI: 10.1038/S41590-019-0421-2 | 0.353 | |||
| 2019 | Liu Q, Liang X, Wang Q, Wilson EN, Lam R, Wang J, Kong W, Tsai C, Pan T, Larkin PB, Shamloo M, Andreasson KI. PGE signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America. PMID 31036664 DOI: 10.1073/Pnas.1818544116 | 0.401 | |||
| 2018 | Ravina K, Briggs DI, Kislal S, Warraich Z, Nguyen T, Lam RK, Zarembinski TI, Shamloo M. Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke. International Journal of Molecular Sciences. 19. PMID 30486515 DOI: 10.3390/Ijms19123782 | 0.352 | |||
| 2018 | Huang WH, Wang DC, Allen WE, Klope M, Hu H, Shamloo M, Luo L. Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30275311 DOI: 10.1073/Pnas.1806796115 | 0.331 | |||
| 2018 | Djurisic M, Brott BK, Saw NL, Shamloo M, Shatz CJ. Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids. Molecular Psychiatry. PMID 29670176 DOI: 10.1038/S41380-018-0034-4 | 0.317 | |||
| 2018 | Joshi AU, Saw NL, Shamloo M, Mochly-Rosen D. Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease. Oncotarget. 9: 6128-6143. PMID 29464060 DOI: 10.18632/Oncotarget.23640 | 0.318 | |||
| 2018 | Joshi AU, Saw NL, Vogel H, Cunnigham AD, Shamloo M, Mochly-Rosen D. Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. Embo Molecular Medicine. PMID 29335339 DOI: 10.15252/Emmm.201708166 | 0.301 | |||
| 2017 | Yi B, Jahangir A, Evans AK, Briggs D, Ravina K, Ernest J, Farimani AB, Sun W, Rajadas J, Green M, Feinberg EN, Pande VS, Shamloo M. Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. Plos One. 12: e0180319. PMID 28746336 DOI: 10.1371/Journal.Pone.0180319 | 0.352 | |||
| 2017 | Ardestani PM, Evans AK, Yi B, Nguyen T, Coutellier L, Shamloo M. Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist. Neuropharmacology. PMID 28089846 DOI: 10.1016/J.Neuropharm.2017.01.010 | 0.353 | |||
| 2016 | Simmons DA, Belichenko NP, Ford EC, Semaan S, Monbureau M, Aiyaswamy S, Holman CM, Condon C, Shamloo M, Massa SM, Longo FM. A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 25: 4920-4938. PMID 28171570 DOI: 10.1093/Hmg/Ddw316 | 0.344 | |||
| 2016 | Yi B, Sahn JJ, Ardestani PM, Evans AK, Scott L, Chan JZ, Iyer S, Crisp A, Zuniga G, Pierce-Shimomura J, Martin SF, Shamloo M. Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuro-inflammation in experimental models of Alzheimer's disease. Journal of Neurochemistry. PMID 27926996 DOI: 10.1111/Jnc.13917 | 0.362 | |||
| 2016 | Disatnik MH, Joshi AU, Saw NL, Shamloo M, Leavitt BR, Qi X, Mochly-Rosen D. Potential biomarkers to follow the progression and treatment response of Huntington's disease. The Journal of Experimental Medicine. PMID 27821553 DOI: 10.1084/Jem.20160776 | 0.315 | |||
| 2016 | Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L. Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. PMID 27693255 DOI: 10.1016/J.Neuron.2016.09.019 | 0.314 | |||
| 2015 | Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, ... ... Shamloo M, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature Medicine. PMID 26390242 DOI: 10.1038/Nm.3951 | 0.33 | |||
| 2014 | Izzo NJ, Staniszewski A, To L, Fa M, Teich AF, Saeed F, Wostein H, Walko T, Vaswani A, Wardius M, Syed Z, Ravenscroft J, Mozzoni K, Silky C, Rehak C, ... ... Shamloo M, et al. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits. Plos One. 9: e111898. PMID 25390368 DOI: 10.1371/Journal.Pone.0111898 | 0.378 | |||
| 2014 | Nguyen TV, Shen L, Vander Griend L, Quach LN, Belichenko NP, Saw N, Yang T, Shamloo M, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice. Journal of Alzheimer's Disease : Jad. 42: 459-83. PMID 24898660 DOI: 10.3233/Jad-140036 | 0.372 | |||
| 2014 | Coutellier L, Ardestani PM, Shamloo M. β1-adrenergic receptor activation enhances memory in Alzheimer's disease model. Annals of Clinical and Translational Neurology. 1: 348-360. PMID 24883337 DOI: 10.1002/Acn3.57 | 0.324 | |||
| 2014 | Kallop DY, Meilandt WJ, Gogineni A, Easley-Neal C, Wu T, Jubb AM, Yaylaoglu M, Shamloo M, Tessier-Lavigne M, Scearce-Levie K, Weimer RM. A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6425-37. PMID 24806669 DOI: 10.1523/Jneurosci.4963-13.2014 | 0.36 | |||
| 2014 | Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, ... ... Shamloo M, et al. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Reports. 7: 1077-92. PMID 24794428 DOI: 10.1016/J.Celrep.2014.03.036 | 0.331 | |||
| 2013 | Simmons DA, Belichenko NP, Yang T, Condon C, Monbureau M, Shamloo M, Jing D, Massa SM, Longo FM. A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18712-27. PMID 24285878 DOI: 10.1523/Jneurosci.1310-13.2013 | 0.385 | |||
| 2013 | Guo X, Disatnik MH, Monbureau M, Shamloo M, Mochly-Rosen D, Qi X. Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration. The Journal of Clinical Investigation. 123: 5371-88. PMID 24231356 DOI: 10.1172/Jci70911 | 0.313 | |||
| 2013 | Stephan AH, Madison DV, Mateos JM, Fraser DA, Lovelett EA, Coutellier L, Kim L, Tsai HH, Huang EJ, Rowitch DH, Berns DS, Tenner AJ, Shamloo M, Barres BA. A dramatic increase of C1q protein in the CNS during normal aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13460-74. PMID 23946404 DOI: 10.1523/Jneurosci.1333-13.2013 | 0.363 | |||
| 2013 | Beraki S, Litrus L, Soriano L, Monbureau M, To LK, Braithwaite SP, Nikolich K, Urfer R, Oksenberg D, Shamloo M. A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. Plos One. 8: e69233. PMID 23874920 DOI: 10.1371/Journal.Pone.0069233 | 0.349 | |||
| 2013 | Hanson JE, Weber M, Meilandt WJ, Wu T, Luu T, Deng L, Shamloo M, Sheng M, Scearce-Levie K, Zhou Q. GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1221-33. PMID 23340518 DOI: 10.1038/Npp.2013.19 | 0.382 | |||
| 2012 | Salih DA, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, et al. FoxO6 regulates memory consolidation and synaptic function. Genes & Development. 26: 2780-801. PMID 23222102 DOI: 10.1101/Gad.208926.112 | 0.337 | |||
| 2012 | Pollak J, Doyle KP, Mamer L, Shamloo M, Buckwalter MS. Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model. Brain and Behavior. 2: 698-706. PMID 23139913 DOI: 10.1002/Brb3.77 | 0.313 | |||
| 2012 | Coutellier L, Beraki S, Ardestani PM, Saw NL, Shamloo M. Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant to developmental disorders. Plos One. 7: e46604. PMID 23029555 DOI: 10.1371/Journal.Pone.0046604 | 0.344 | |||
| 2012 | Kleschevnikov AM, Belichenko PV, Faizi M, Jacobs LF, Htun K, Shamloo M, Mobley WC. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9217-27. PMID 22764230 DOI: 10.1523/Jneurosci.1673-12.2012 | 0.334 | |||
| 2012 | Faizi M, Bader PL, Saw N, Nguyen TV, Beraki S, Wyss-Coray T, Longo FM, Shamloo M. Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function. Brain and Behavior. 2: 142-54. PMID 22574282 DOI: 10.1002/Brb3.41 | 0.347 | |||
| 2011 | Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, Larsen DM, Crish JF, Bebek G, Ritter SY, Lindstrom TM, Hwang I, Wong HH, Punzi L, Encarnacion A, Shamloo M, et al. Identification of a central role for complement in osteoarthritis. Nature Medicine. 17: 1674-9. PMID 22057346 DOI: 10.1038/Nm.2543 | 0.302 | |||
| 2011 | Bader PL, Faizi M, Kim LH, Owen SF, Tadross MR, Alfa RW, Bett GC, Tsien RW, Rasmusson RL, Shamloo M. Mouse model of Timothy syndrome recapitulates triad of autistic traits. Proceedings of the National Academy of Sciences of the United States of America. 108: 15432-7. PMID 21878566 DOI: 10.1073/Pnas.1112667108 | 0.304 | |||
| 2011 | Etherton M, Földy C, Sharma M, Tabuchi K, Liu X, Shamloo M, Malenka RC, Südhof TC. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proceedings of the National Academy of Sciences of the United States of America. 108: 13764-9. PMID 21808020 DOI: 10.1073/Pnas.1111093108 | 0.338 | |||
| 2011 | Horie N, Pereira MP, Niizuma K, Sun G, Keren-Gill H, Encarnacion A, Shamloo M, Hamilton SA, Jiang K, Huhn S, Palmer TD, Bliss TM, Steinberg GK. Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair. Stem Cells (Dayton, Ohio). 29: 274-85. PMID 21732485 DOI: 10.1002/Stem.584 | 0.306 | |||
| 2011 | Faizi M, Bader PL, Tun C, Encarnacion A, Kleschevnikov A, Belichenko P, Saw N, Priestley M, Tsien RW, Mobley WC, Shamloo M. Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer. Neurobiology of Disease. 43: 397-413. PMID 21527343 DOI: 10.1016/J.Nbd.2011.04.011 | 0.355 | |||
| 2011 | Lan WC, Priestley M, Mayoral SR, Tian L, Shamloo M, Penn AA. Sex-specific cognitive deficits and regional brain volume loss in mice exposed to chronic, sublethal hypoxia. Pediatric Research. 70: 15-20. PMID 21436761 DOI: 10.1203/Pdr.0B013E31821B98A3 | 0.333 | |||
| 2011 | Ruscher K, Shamloo M, Rickhag M, Ladunga I, Soriano L, Gisselsson L, Toresson H, Ruslim-Litrus L, Oksenberg D, Urfer R, Johansson BB, Nikolich K, Wieloch T. The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Brain : a Journal of Neurology. 134: 732-46. PMID 21278085 DOI: 10.1093/Brain/Awq367 | 0.398 | |||
| 2011 | Encarnacion A, Horie N, Keren-Gill H, Bliss TM, Steinberg GK, Shamloo M. Long-term behavioral assessment of function in an experimental model for ischemic stroke. Journal of Neuroscience Methods. 196: 247-57. PMID 21256866 DOI: 10.1016/J.Jneumeth.2011.01.010 | 0.347 | |||
| 2010 | Ishizaki T, Erickson A, Kuric E, Shamloo M, Hara-Nishimura I, Inácio AR, Wieloch T, Ruscher K. The asparaginyl endopeptidase legumain after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1756-66. PMID 20234379 DOI: 10.1038/Jcbfm.2010.39 | 0.391 | |||
| 2009 | Salehi A, Faizi M, Colas D, Valletta J, Laguna J, Takimoto-Kimura R, Kleschevnikov A, Wagner SL, Aisen P, Shamloo M, Mobley WC. Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome. Science Translational Medicine. 1: 7ra17. PMID 20368182 DOI: 10.1126/Scitranslmed.3000258 | 0.319 | |||
| 2008 | Braithwaite SP, Xu J, Leung J, Urfer R, Nikolich K, Oksenberg D, Lombroso PJ, Shamloo M. Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. The European Journal of Neuroscience. 27: 2444-52. PMID 18445231 DOI: 10.1111/J.1460-9568.2008.06209.X | 0.389 | |||
| 2006 | Shamloo M, Soriano L, von Schack D, Rickhag M, Chin DJ, Gonzalez-Zulueta M, Gido G, Urfer R, Wieloch T, Nikolich K. Npas4, a novel helix-loop-helix PAS domain protein, is regulated in response to cerebral ischemia. The European Journal of Neuroscience. 24: 2705-20. PMID 17156197 DOI: 10.1111/J.1460-9568.2006.05172.X | 0.361 | |||
| 2006 | Rickhag M, Wieloch T, Gidö G, Elmér E, Krogh M, Murray J, Lohr S, Bitter H, Chin DJ, von Schack D, Shamloo M, Nikolich K. Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue. Journal of Neurochemistry. 96: 14-29. PMID 16300643 DOI: 10.1111/J.1471-4159.2005.03508.X | 0.364 | |||
| 2005 | Shamloo M, Soriano L, Wieloch T, Nikolich K, Urfer R, Oksenberg D. Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemia. The Journal of Biological Chemistry. 280: 42290-9. PMID 16204252 DOI: 10.1074/Jbc.M505804200 | 0.401 | |||
| 2004 | Matsumoto S, Shamloo M, Matsumoto E, Isshiki A, Wieloch T. Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 54-61. PMID 14688616 DOI: 10.1097/01.Wcb.0000095920.70924.F5 | 0.354 | |||
| 2003 | Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K, Wieloch T. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nature Medicine. 9: 1062-8. PMID 12858170 DOI: 10.1038/Nm903 | 0.395 | |||
| 2002 | Matsumoto S, Shamloo M, Isshiki A, Wieloch T. Persistent phosphorylation of synaptic proteins following middle cerebral artery occlusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1107-13. PMID 12218416 DOI: 10.1097/00004647-200209000-00008 | 0.4 | |||
| 2000 | Shamloo M, Kamme F, Wieloch T. Subcellular distribution and autophosphorylation of calcium/calmodulin- dependent protein kinase II-α in rat hippocampus in a model of ischemic tolerance Neuroscience. 96: 665-674. PMID 10727785 DOI: 10.1016/S0306-4522(99)00586-2 | 0.351 | |||
| 1999 | Shamloo M, Rytter A, Wieloch T. Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning. Neuroscience. 93: 81-88. PMID 10430472 DOI: 10.1016/S0306-4522(99)00137-2 | 0.341 | |||
| 1999 | Tomasevic G, Shamloo M, Israeli D, Wieloch T. Activation of p53 and its target genes p21WAF1/Cip1 and PAG608/Wig-1 in ischemic preconditioning Molecular Brain Research. 70: 304-313. PMID 10407180 DOI: 10.1016/S0169-328X(99)00146-1 | 0.385 | |||
| 1999 | Shamloo M, Wieloch T. Rapid decline in protein kinase Cγ levels in the synaptosomal fraction of rat hippocampus after ischemic preconditioning Neuroreport. 10: 931-935. PMID 10321462 DOI: 10.1097/00001756-199904060-00007 | 0.406 | |||
| 1999 | Shamloo M, Wieloch T. Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance. Journal of Cerebral Blood Flow and Metabolism. 19: 173-183. PMID 10027773 DOI: 10.1097/00004647-199902000-00009 | 0.415 | |||
| 1998 | Khaspekov L, Shamloo M, Victorov I, Wieloch T. Sublethal in vitro glucose-oxygen deprivation protects cultured hippocampal neurons against a subsequent severe insult Neuroreport. 9: 1273-1276. PMID 9631411 DOI: 10.1097/00001756-199805110-00003 | 0.327 | |||
| 1998 | Rundén E, Seglen PO, Haug FM, Ottersen OP, Wieloch T, Shamloo M, Laake JH. Regional Selective Neuronal Degeneration after Protein Phosphatase Inhibition in Hippocampal Slice Cultures: Evidence for a MAP Kinase-Dependent Mechanism The Journal of Neuroscience. 18: 7296-7305. DOI: 10.1523/Jneurosci.18-18-07296.1998 | 0.321 | |||
| 1997 | Wieloch T, Hu B, Shamloo M. Aberrant Cell Signaling in the Postischemic Brain: An Integrated View Primer On Cerebrovascular Diseases. 227-230. DOI: 10.1016/B978-012743170-3.50066-2 | 0.356 | |||
| 1996 | Li P, Kristián T, Shamloo M, Siesjö BK. Effects of Preischemic Hyperglycemia on Brain Damage Incurred by Rats Subjected to 2.5 or5 Minutes of Forebrain Ischemia Stroke. 27: 1592-1602. PMID 8784135 DOI: 10.1161/01.Str.27.9.1592 | 0.338 | |||
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