Yi Liu - Publications

Affiliations: 
Johnson & Johnson Pharmaceutical Research and Development, Spring House, Pennsylvania, Saarbrücken, PA, United States 
Area:
ion channels, pain

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Parsons WH, Calvo RR, Cheung W, Lee YK, Patel S, Liu J, Youngman MA, Dax SL, Stone D, Qin N, Hutchinson T, Lubin ML, Zhang SP, Finley M, Liu Y, et al. Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep). Journal of Medicinal Chemistry. 58: 3859-74. PMID 25850459 DOI: 10.1021/acs.jmedchem.5b00132  0.32
2010 Finley MF, Lubin ML, Neeper MP, Beck E, Liu Y, Flores CM, Qin N. An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists. Assay and Drug Development Technologies. 8: 685-94. PMID 21050074 DOI: 10.1089/adt.2010.0311  0.32
2009 Parker MH, Smith-Swintosky VL, McComsey DF, Huang Y, Brenneman D, Klein B, Malatynska E, White HS, Milewski ME, Herb M, Finley MF, Liu Y, Lubin ML, Qin N, Iannucci R, et al. Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies. Journal of Medicinal Chemistry. 52: 7528-36. PMID 19388676 DOI: 10.1021/jm801432r  0.32
2009 Mathes C, Friis S, Finley M, Liu Y. QPatch: the missing link between HTS and ion channel drug discovery. Combinatorial Chemistry & High Throughput Screening. 12: 78-95. PMID 19149494 DOI: 10.2174/138620709787047948  0.32
2009 Liu Y, Yohrling GJ, Wang Y, Hutchinson TL, Brenneman DE, Flores CM, Zhao B. Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons. Epilepsy Research. 83: 66-72. PMID 19013768 DOI: 10.1016/j.eplepsyres.2008.09.006  0.32
2007 Neeper MP, Liu Y, Hutchinson TL, Wang Y, Flores CM, Qin N. Activation properties of heterologously expressed mammalian TRPV2: evidence for species dependence. The Journal of Biological Chemistry. 282: 15894-902. PMID 17395593 DOI: 10.1074/jbc.M608287200  0.32
2006 Liu Y, Qin N, Reitz T, Wang Y, Flores CM. Inhibition of the rat brain sodium channel Nav1.2 after prolonged exposure to gabapentin. Epilepsy Research. 70: 263-8. PMID 16621448 DOI: 10.1016/j.eplepsyres.2006.03.007  0.32
2006 Liu Y, Lubin ML, Reitz TL, Wang Y, Colburn RW, Flores CM, Qin N. Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine. European Journal of Pharmacology. 530: 23-32. PMID 16386244 DOI: 10.1016/j.ejphar.2005.11.033  0.32
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