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Stefan Siwko, Ph.D. - Publications

Affiliations: 
2005 Stanford University, Palo Alto, CA 
Area:
chemical and systems biology
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28/50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen R, Jing J, Siwko S, Huang Y, Zhou Y. Intelligent cell-based therapies for cancer and autoimmune disorders. Current Opinion in Biotechnology. 66: 207-216. PMID 32956902 DOI: 10.1016/J.Copbio.2020.08.012  0.321
2020 Zhang C, Qin J, Zhang S, Zhang N, Tan B, Siwko S, Zhang Y, Wang Q, Chen J, Qian M, Liu M, Du B. ADP/P2Y aggravates inflammatory bowel disease through ERK5-mediated NLRP3 inflammasome activation. Mucosal Immunology. PMID 32518369 DOI: 10.1038/S41385-020-0307-5  0.33
2020 Li L, Duan Q, Zeng Z, Zhao J, Lu J, Sun J, Zhang J, Siwko S, Wong J, Shi T, Zhang X, Liu M, Chen J, Li D. UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β-catenin signaling. International Journal of Cancer. PMID 32372448 DOI: 10.1002/Ijc.33036  0.361
2020 Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J. Regulation of body length and bone mass by Gpr126/Adgrg6. Science Advances. 6: eaaz0368. PMID 32219165 DOI: 10.1126/Sciadv.Aaz0368  0.333
2019 Luo J, Sun P, Siwko S, Liu M, Xiao J. The role of GPCRs in bone diseases and dysfunctions. Bone Research. 7: 19. PMID 31646011 DOI: 10.1038/S41413-019-0059-6  0.317
2018 Li Z, Huang J, Wang F, Li W, Wu X, Zhao C, Zhao J, Wei H, Wu Z, Qian M, Sun P, He L, Jin Y, Tang J, Qiu W, ... Siwko S, et al. Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30536462 DOI: 10.1002/Jbmr.3652  0.337
2018 Sun P, Jia K, Zheng C, Zhu X, Li J, He L, Siwko S, Xue F, Liu M, Luo J. Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells. Journal of Cellular Physiology. PMID 30536377 DOI: 10.1002/Jcp.27927  0.337
2018 Xiong Q, Huang H, Wang N, Chen R, Chen N, Han H, Wang Q, Siwko S, Liu M, Qian M, Du B. Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses. Frontiers in Immunology. 9: 2289. PMID 30333836 DOI: 10.3389/Fimmu.2018.02289  0.326
2018 Huang H, Xiong Q, Wang N, Chen R, Ren H, Siwko S, Han H, Liu M, Qian M, Du B. Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity. Science Advances. 4: eaas9784. PMID 30101190 DOI: 10.1126/Sciadv.Aas9784  0.369
2018 Tan B, Shi X, Zhang J, Qin J, Zhang N, Ren H, Qian M, Siwko S, Carmon K, Liu Q, Han H, Du B, Liu M. Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization. Cancer Research. PMID 29967265 DOI: 10.1158/0008-5472.Can-18-0152  0.352
2017 Yue Z, Yuan Z, Zeng L, Wang Y, Lai L, Li J, Sun P, Xue X, Qi J, Yang Z, Zheng Y, Fang Y, Li D, Siwko S, Li Y, et al. LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29269400 DOI: 10.1096/Fj.201700897R  0.385
2017 Luo W, Tan P, Rodriguez M, He L, Tan K, Zeng L, Siwko S, Liu M. Leucine-rich repeat-containing G protein coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition. The Journal of Biological Chemistry. PMID 28768769 DOI: 10.1074/Jbc.M116.771931  0.379
2017 Li J, Jing J, Bai Y, Li Z, Xing R, Tan B, Ma X, Qiu W, Du C, Du B, Yang F, Tang J, Siwko S, Liu M, Chen H, et al. SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the Th17/Treg Balance. Molecular Pharmacology. PMID 28213589 DOI: 10.1124/Mol.116.107136  0.337
2016 Chen S, Bai Y, Li Z, Jia K, Jin Y, He B, Qiu WW, Du C, Siwko S, Chen H, Liu M, Luo J. A Betulinic Acid Derivative SH479 Inhibits Collagen-induced Arthritis by Modulating T Cell Differentiation and Cytokine Balance. Biochemical Pharmacology. PMID 27965071 DOI: 10.1016/J.Bcp.2016.12.006  0.3
2016 Rodriguez M, Siwko S, Liu M. Prostate-Specific G-protein coupled receptor, an emerging biomarker regulating inflammation and prostate cancer invasion. Current Molecular Medicine. PMID 27280498 DOI: 10.2174/1566524016666160607091333  0.328
2016 Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, et al. LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption. Nature Medicine. PMID 27064449 DOI: 10.1038/Nm.4076  0.375
2015 Rodriguez M, Siwko S, Zeng L, Li J, Yi Z, Liu M. Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression. Oncogene. PMID 26028029 DOI: 10.1038/Onc.2015.170  0.351
2015 Guan Y, Zhang L, Li X, Zhang X, Liu S, Gao N, Li L, Gao G, Wei G, Chen Z, Zheng Y, Ma X, Siwko S, Chen JL, Liu M, et al. Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models. Journal of Immunology (Baltimore, Md. : 1950). 195: 339-46. PMID 26026060 DOI: 10.4049/Jimmunol.1303356  0.374
2014 Tan K, Cho SG, Luo W, Yi T, Wu X, Siwko S, Liu M, Yuan W. KiSS1-induced GPR54 signaling inhibits breast cancer cell migration and epithelial-mesenchymal transition via protein kinase D1. Current Molecular Medicine. 14: 652-62. PMID 24894166 DOI: 10.2174/1566524014666140603115314  0.396
2014 Wang Y, Cho SG, Wu X, Siwko S, Liu M. G-protein coupled receptor 124 (GPR124) in endothelial cells regulates vascular endothelial growth factor (VEGF)-induced tumor angiogenesis Current Molecular Medicine. 14: 543-554. PMID 24730523 DOI: 10.2174/1566524014666140414205943  0.302
2014 Peng G, Chun-Jen Lin C, Mo W, Dai H, Park YY, Kim SM, Peng Y, Mo Q, Siwko S, Hu R, Lee JS, Hennessy B, Hanash S, Mills GB, Lin SY. Genome-wide transcriptome profiling of homologous recombination DNA repair. Nature Communications. 5: 3361. PMID 24553445 DOI: 10.1038/Ncomms4361  0.306
2013 Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, Zhao C, Siwko S, Shi T, Wang P, Xiao J, Liu M, Luo J. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway. Cancer Research. 73: 6206-18. PMID 24008316 DOI: 10.1158/0008-5472.Can-13-1049  0.381
2013 Luo W, Rodriguez M, Valdez JM, Zhu X, Tan K, Li D, Siwko S, Xin L, Liu M. Lgr4 is a key regulator of prostate development and prostate stem cell differentiation. Stem Cells (Dayton, Ohio). 31: 2492-505. PMID 23897697 DOI: 10.1002/Stem.1484  0.336
2013 Siwko S, Lai L, Weng J, Liu M. Lgr4 in ocular development and glaucoma. Journal of Ophthalmology. 2013: 987494. PMID 23840940 DOI: 10.1155/2013/987494  0.33
2013 Wang Y, Dong J, Li D, Lai L, Siwko S, Li Y, Liu M. Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2. Stem Cells (Dayton, Ohio). 31: 1921-31. PMID 23712846 DOI: 10.1002/Stem.1438  0.363
2011 Graff JR, Konicek B, Dumstorf C, Siwko S, Colligan B, Deddens JA, Douglass L, Carter JH. Abstract LB-384: Elevated eIF4E phosphorylation is associated with advanced malignancy and decreased patient survival and can be therapeutically inhibited by a novel, orally bio-available Mnk inhibitor Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-384  0.383
2009 Yim EK, Siwko S, Lin SY. Exploring Rak tyrosine kinase function in breast cancer. Cell Cycle (Georgetown, Tex.). 8: 2360-4. PMID 19597351 DOI: 10.4161/Cc.8.15.9264  0.412
2007 Siwko S, Mochly-Rosen D. Use of a novel method to find substrates of protein kinase C delta identifies M2 pyruvate kinase. The International Journal of Biochemistry & Cell Biology. 39: 978-87. PMID 17337233 DOI: 10.1016/J.Biocel.2007.01.018  0.45
Low-probability matches (unlikely to be authored by this person)
2020 Lu W, Yu W, He J, Liu W, Yang J, Lin X, Zhang Y, Wang X, Jiang W, Luo J, Zhang Q, Yang H, Peng S, Yi Z, Ren S, ... ... Siwko S, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. Embo Molecular Medicine. e12798. PMID 33283987 DOI: 10.15252/emmm.202012798  0.293
2014 Yi T, Weng J, Siwko S, Luo J, Li D, Liu M. LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects. The Journal of Biological Chemistry. 289: 8767-80. PMID 24519938 DOI: 10.1074/Jbc.M113.530816  0.28
2017 Zhang N, Huang H, Tan B, Wei Y, Xiong Q, Yan Y, Hou L, Wu N, Siwko S, Cimarelli A, Xu J, Han H, Qian M, Liu M, Du B. Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein. The Journal of Biological Chemistry. PMID 28842478 DOI: 10.1074/Jbc.M117.802090  0.275
2008 Siwko SK, Bu W, Gutierrez C, Lewis B, Jechlinger M, Schaffhausen B, Li Y. Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors. Neoplasia (New York, N.Y.). 10: 653-62, 1 p followin. PMID 18592025 DOI: 10.1593/Neo.08266  0.273
2014 Rodriguez M, Luo W, Weng J, Zeng L, Yi Z, Siwko S, Liu M. PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB. Oncogenesis. 3: e114. PMID 25111863 DOI: 10.1038/oncsis.2014.29  0.261
2020 Zhang X, Zhu B, Chen L, Xie L, Yu W, Wang Y, Li L, Yin S, Yang L, Hu H, Han H, Li Y, Wang L, Chen G, Ma X, ... ... Siwko S, et al. Dual base editor catalyzes both cytosine and adenine base conversions in human cells. Nature Biotechnology. PMID 32483363 DOI: 10.1038/S41587-020-0527-Y  0.259
2022 Li R, Guan Z, Bi S, Wang F, He L, Niu X, You Y, Liu Y, Ding Y, Siwko S, Wang N, Zhang Z, Jin Y, Luo J. The proton-activated G protein-coupled receptor GPR4 regulates the development of osteoarthritis via modulating CXCL12/CXCR7 signaling. Cell Death & Disease. 13: 152. PMID 35165253 DOI: 10.1038/s41419-021-04455-4  0.253
2024 Li Z, Yang X, Fu R, Wu Z, Xu S, Jiao J, Qian M, Zhang L, Wu C, Xie T, Yao J, Wu Z, Li W, Ma G, You Y, ... ... Siwko S, et al. Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src. Nature Communications. 15: 1300. PMID 38346942 DOI: 10.1038/s41467-024-44852-9  0.251
2012 Cho SG, Li D, Tan K, Siwko SK, Liu M. KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis. Cancer Metastasis Reviews. 31: 585-91. PMID 22692479 DOI: 10.1007/S10555-012-9367-7  0.251
2021 Yue Z, Niu X, Yuan Z, Qin Q, Jiang W, He L, Gao J, Ding Y, Liu Y, Xu Z, Li Z, Yang Z, Li R, Xue X, Gao Y, ... ... Siwko S, et al. RSPO2/RANKL-LGR4 signaling regulates osteoclastic pre-metastatic niche formation and bone metastasis. The Journal of Clinical Investigation. PMID 34847079 DOI: 10.1172/JCI144579  0.242
2020 Wang F, Ma L, Ding Y, He L, Chang M, Shan Y, Siwko S, Chen G, Liu Y, Jin Y, Peng X, Luo J. Fatty acid sensing GPCR (GPR84) signaling safeguards cartilage homeostasis and protects against osteoarthritis. Pharmacological Research. 105406. PMID 33359913 DOI: 10.1016/j.phrs.2020.105406  0.228
2022 Xie J, Ma G, Zhou L, He L, Zhang Z, Tan P, Huang Z, Fang S, Wang T, Lee YT, Wen S, Siwko S, Wang L, Liu J, Du Y, et al. Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2103940. PMID 35076181 DOI: 10.1002/advs.202103940  0.228
2008 Siwko SK, Dong J, Lewis MT, Liu H, Hilsenbeck SG, Li Y. Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer. Stem Cells (Dayton, Ohio). 26: 3205-9. PMID 18787212 DOI: 10.1634/Stemcells.2008-0103  0.223
2019 Yang L, Zhang X, Wang L, Yin S, Zhu B, Xie L, Duan Q, Hu H, Zheng R, Wei Y, Peng L, Han H, Zhang J, Qiu W, Geng H, ... Siwko S, et al. Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants. Protein & Cell. PMID 31087276 DOI: 10.1007/S13238-019-0631-2  0.204
2021 He L, Huang Z, Huang K, Chen R, Nguyen NT, Wang R, Cai X, Huang Z, Siwko S, Walker JR, Han G, Zhou Y, Jing J. Optogenetic Control of Non-Apoptotic Cell Death. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2100424. PMID 34540558 DOI: 10.1002/advs.202100424  0.203
2022 Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D, Luan C, Zhang S, Wu H, Gao H, Bai S, Li C, Ding R, Xue N, ... ... Siwko S, et al. Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing. Nature Biotechnology. PMID 36357717 DOI: 10.1038/s41587-022-01532-7  0.155
2022 Li J, Hong T, Wei Y, Guo L, Lee M, Yang H, Class C, Yang Y, Wang X, He H, Siwko S, You MJ, Zhou Y, Garcia-Manero G, Huang Y. Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms. Clinical Epigenetics. 14: 81. PMID 35765052 DOI: 10.1186/s13148-022-01297-5  0.123
2018 Yang L, Zhang X, Wang L, Yin S, Zhu B, Xie L, Duan Q, Hu H, Zheng R, Wei Y, Peng L, Han H, Zhang J, Qiu W, Geng H, ... Siwko S, et al. Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants. Protein & Cell. PMID 30066232 DOI: 10.1007/s13238-018-0568-x  0.092
2021 He L, Wang L, Zeng H, Tan P, Ma G, Zheng S, Li Y, Sun L, Dou F, Siwko S, Huang Y, Wang Y, Zhou Y. Engineering of a bona fide light-operated calcium channel. Nature Communications. 12: 164. PMID 33431868 DOI: 10.1038/s41467-020-20425-4  0.081
2021 Ye W, Siwko S, Tsai RYL. Sex and Race-Related DNA Methylation Changes in Hepatocellular Carcinoma. International Journal of Molecular Sciences. 22. PMID 33917049 DOI: 10.3390/ijms22083820  0.073
2021 Peng H, Xu H, Wu J, Li J, Zhou Y, Ding Z, Siwko SK, Yuan X, Schalinske KL, Alpini G, Zhang KK, Xie L. Maternal High-Fat Diet Disrupted One-Carbon Metabolism in Offspring, contributing to Nonalcoholic Fatty Liver Disease. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 33529448 DOI: 10.1111/liv.14811  0.057
2009 Siwko SK, Dong J, Lewis MT, Liu H, Hilsenbeck SG, Li Y. Response to the letter by Smith et al Stem Cells. 27: 1224-1225. DOI: 10.1002/Stem.20  0.01
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