Craig S. Atwood, PhD, University of Western Australia,1993 - Publications

Affiliations: 
Medicine University of Wisconsin, Madison, Madison, WI 
Area:
Alzheimer disease and Aging
Website:
http://agingresearch.wisc.edu/atwood.htm

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Geddes RI, Kapoor A, Hayashi K, Rauh R, Wehber M, Bongers Q, Jansen AD, Anderson IM, Farquhar G, Vadakkadath-Meethal S, Ziegler TE, Atwood CS. Hypogonadism induced by surgical stress and brain trauma is reversed by human chorionic gonadotropin in male rats: A potential therapy for surgical and TBI-induced hypogonadism? Endocrinology, Diabetes & Metabolism. 4: e00239. PMID 34277964 DOI: 10.1002/edm2.239  0.435
2021 Butler T, Goldberg JD, Galvin JE, Maloney T, Ravdin L, Glodzik L, de Leon MJ, Hochman T, Bowen RL, Atwood CS. Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus cholinesterase inhibition to reduce neurologic decline in Alzheimer's. Contemporary Clinical Trials. 106488. PMID 34166841 DOI: 10.1016/j.cct.2021.106488  0.516
2020 Hayashi K, Gonzales TK, Kapoor A, Ziegler TE, Meethal SV, Atwood CS. Development of Classification Models for the Prediction of Alzheimer's Disease Utilizing Circulating Sex Hormone Ratios. Journal of Alzheimer's Disease : Jad. PMID 32623397 DOI: 10.3233/Jad-200418  0.569
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Atwood CS, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.432
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Atwood CS, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.429
2019 Butler T, Bowen R, Atwood CS. Septal hypertrophy and cell cycle re-entry in AD. Aging. PMID 30668543 DOI: 10.18632/aging.101777  0.446
2018 Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. Journal of Alzheimer's Disease : Jad. PMID 29782310 DOI: 10.3233/Jad-170847  0.711
2017 Geddes RI, Hayashi K, Bongers Q, Wehber M, Anderson IM, Jansen AD, Nier C, Fares E, Farquhar G, Kapoor A, Ziegler TE, Vadakkadath Meethal S, Bird IM, Atwood CS. Correction: Conjugated Linoleic Acid Administration Induces Amnesia in Male Sprague Dawley Rats and Exacerbates Recovery from Functional Deficits Induced by a Controlled Cortical Impact Injury. Plos One. 12: e0188611. PMID 29161323 DOI: 10.1371/Journal.Pone.0188611  0.752
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Atwood CS, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.491
2017 Atwood CS, Hayashi K, Meethal SV, Gonzales T, Bowen RL. Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species. Geroscience. PMID 28271270 DOI: 10.1007/s11357-016-9955-5  0.597
2017 Geddes RI, Hayashi K, Bongers Q, Wehber M, Anderson IM, Jansen AD, Nier C, Fares E, Farquhar G, Kapoor A, Ziegler TE, VadakkadathMeethal S, Bird IM, Atwood CS. Conjugated Linoleic Acid Administration Induces Amnesia in Male Sprague Dawley Rats and Exacerbates Recovery from Functional Deficits Induced by a Controlled Cortical Impact Injury. Plos One. 12: e0169494. PMID 28125600 DOI: 10.1371/journal.pone.0169494  0.41
2016 Bowen RL, Butler T, Atwood CS. Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27298416 DOI: 10.1200/Jco.2015.66.3997  0.556
2016 Hoscheidt SM, Starks EJ, Oh JM, Zetterberg H, Blennow K, Krause RA, Gleason CE, Puglielli L, Atwood CS, Carlsson CM, Asthana S, Johnson SC, Bendlin BB. Insulin Resistance is Associated with Increased Alzheimer's Disease Pathology and Reduced Memory Function in At-Risk Healthy Middle-Aged Adults. Journal of Alzheimer's Disease : Jad. PMID 27079723 DOI: 10.3233/Jad-160110  0.362
2015 Atwood CS, Bowen RL. A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis. Journal of Alzheimer's Disease : Jad. 47: 33-47. PMID 26402752 DOI: 10.3233/Jad-143210  0.606
2015 Atwood CS, Bowen RL. The Endocrine Dyscrasia that Accompanies Menopause and Andropause Induces Aberrant Cell Cycle Signaling that Triggers Re-entry of Post-mitotic Neurons into the Cell Cycle, Neurodysfunction, Neurodegeneration and Cognitive Disease. Hormones and Behavior. PMID 26188949 DOI: 10.1016/J.Yhbeh.2015.06.021  0.607
2015 Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. Journal of Alzheimer's Disease : Jad. 44: 549-60. PMID 25310993 DOI: 10.3233/Jad-141626  0.675
2013 Yonker JA, Chang V, Roetker NS, Hauser TS, Hauser RM, Atwood CS. Hypothalamic-pituitary-gonadal axis homeostasis predicts longevity. Age (Dordrecht, Netherlands). 35: 129-38. PMID 22139381 DOI: 10.1007/S11357-011-9342-1  0.32
2012 Clark I, Atwood C, Bowen R, Paz-Filho G, Vissel B. Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales. Pharmacological Reviews. 64: 1004-26. PMID 22966039 DOI: 10.1124/Pr.112.005850  0.559
2012 Vadakkadath Meethal S, Atwood CS. Lactate dyscrasia: a novel explanation for amyotrophic lateral sclerosis. Neurobiology of Aging. 33: 569-81. PMID 20541840 DOI: 10.1016/j.neurobiolaging.2010.04.012  0.768
2011 Clark IA, Atwood CS. Is TNF a link between aging-related reproductive endocrine dyscrasia and Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 27: 691-9. PMID 21891866 DOI: 10.3233/JAD-2011-110887  0.373
2011 Atwood CS, Bowen RL. The reproductive-cell cycle theory of aging: an update. Experimental Gerontology. 46: 100-7. PMID 20851172 DOI: 10.1016/J.Exger.2010.09.007  0.519
2011 Gleason C, Dowling NM, Setchell K, Carlsson C, Barnet J, Johnson S, Atwood C, Asthana S. Findings from a randomized, placebo-control, clinical trial examining the potential cognitive effects of soy isoflavones in patients with Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.112  0.301
2010 Gallego MJ, Porayette P, Kaltcheva MM, Bowen RL, Vadakkadath Meethal S, Atwood CS. The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes. Stem Cell Research & Therapy. 1: 28. PMID 20836886 DOI: 10.1186/Scrt28  0.765
2010 Miller LL, Barnet JH, Blazel HM, Gleason CE, Johnson SC, Marsh AJ, Zetterberg H, Blennow K, Hermann BP, Dowling NM, Puglielli L, Atwood CS, Sager MA, Asthana S, Carlsson CM. The Influence of Metabolic Syndrome on Simvastatin Therapy In Asymptomatic Adults at Risk for Alzheimer's Disease: The ESPRIT Study Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.072  0.302
2010 Carlsson CM, Gleason CE, Johnson SC, Xu G, Huang Y, Barnet J, Fain S, Blazel H, Zetterberg H, Blennow K, Hermann BP, Dowling NM, Newman GC, Puglielli L, Atwood CS, et al. O4-01-06: A randomized, double-blind placebo-controlled trial of simvastatin on CSF, MRI, and cognitive biomarkers in middle-aged adults at risk for Alzheimer's disease: The ESPRIT Study Alzheimer's & Dementia. 6: S151-S152. DOI: 10.1016/J.Jalz.2010.05.470  0.306
2010 Blazel HM, Barnet J, Gleason CE, Dowling NM, Hermann BP, Johnson SC, Zetterberg H, Blennow K, Marsh A, Puglielli L, Atwood C, Sager MA, Asthana S, Carlsson CM. Relationship between CSF biomarkers and language fluency in asymptomatic middle-aged adults at increased risk for Alzheimer's disease: The ESPRIT study Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1697  0.312
2010 Marsh AJ, Barnet JH, Blazel HM, Gleason CE, Johnson SC, Zetterberg H, Blennow K, Hermann BP, Dowling NM, Puglielli L, Atwood CS, Sager MA, Asthana S, Carlsson CM. Mid-life dementia risk scores as a predictor of CSF biomarker response to simvastatin therapy in asymptomatic adults at risk for Alzheimer's disease: The ESPRIT study Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1007  0.308
2009 Porayette P, Gallego MJ, Kaltcheva MM, Bowen RL, Vadakkadath Meethal S, Atwood CS. Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells. The Journal of Biological Chemistry. 284: 23806-17. PMID 19542221 DOI: 10.1074/Jbc.M109.026328  0.785
2009 Meethal SV, Liu T, Chan HW, Ginsburg E, Wilson AC, Gray DN, Bowen RL, Vonderhaar BK, Atwood CS. Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors. Journal of Neurochemistry. 110: 1014-27. PMID 19493163 DOI: 10.1111/J.1471-4159.2009.06192.X  0.657
2009 Atwood C, Bacskai B, Kuchibhotla K, Bezprozvanny I, Chakroborty S, Fagan T, Foskett K, Green K, Goussakov I, Moyer J, Michno K, Rybalchenko V, Stutzmann B, Villalobos C. Alzheimer research forum live discussion: Calcium in AD pathogenesis Journal of Alzheimer's Disease. 16: 909-917. PMID 19387122 DOI: 10.3233/Jad-2009-1026  0.313
2009 Simon DP, Vadakkadath Meethal S, Wilson AC, Gallego MJ, Weinecke SL, Bruce E, Lyons PF, Haasl RJ, Bowen RL, Atwood CS. Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. Neoplasia (New York, N.Y.). 11: 365-76. PMID 19308291 DOI: 10.1593/Neo.81544  0.767
2009 Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radical Research. 43: 156-64. PMID 19160110 DOI: 10.1080/10715760802644694  0.613
2009 Xu G, McLaren DG, Ries ML, Fitzgerald ME, Bendlin BB, Rowley HA, Sager MA, Atwood C, Asthana S, Johnson SC. The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory. Brain : a Journal of Neurology. 132: 383-91. PMID 18829694 DOI: 10.1093/Brain/Awn254  0.318
2009 Gallego MJ, Porayette P, Kaltcheva MM, Meethal SV, Atwood CS. Opioid and progesterone signaling is obligatory for early human embryogenesis. Stem Cells and Development. 18: 737-40. PMID 18803462 DOI: 10.1089/Scd.2008.0190  0.767
2008 Chan HW, Liu T, Verdile G, Bishop G, Haasl RJ, Smith MA, Perry G, Martins RN, Atwood CS. Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity. International Journal of Clinical and Experimental Medicine. 1: 76-88. PMID 19079689  0.777
2008 Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. The Journal of Biological Chemistry. 283: 22550-6. PMID 18505725 DOI: 10.1074/Jbc.M802088200  0.69
2008 Haasl RJ, Ahmadi MR, Meethal SV, Gleason CE, Johnson SC, Asthana S, Bowen RL, Atwood CS. A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele. Bmc Medical Genetics. 9: 37. PMID 18439297 DOI: 10.1186/1471-2350-9-37  0.567
2008 Rodrigues MA, Verdile G, Foster JK, Hogervorst E, Joesbury K, Dhaliwal S, Corder EH, Laws SM, Hone E, Prince R, Devine A, Mehta P, Beilby J, Atwood CS, Martins RN. Gonadotropins and cognition in older women. Journal of Alzheimer's Disease : Jad. 13: 267-74. PMID 18430994 DOI: 10.3233/Jad-2008-13304  0.602
2008 Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Advances in Clinical Chemistry. 45: 139-53. PMID 18429496 DOI: 10.1016/S0065-2423(07)00006-6  0.724
2008 Wilson AC, Clemente L, Liu T, Bowen RL, Meethal SV, Atwood CS. Reproductive hormones regulate the selective permeability of the blood-brain barrier. Biochimica Et Biophysica Acta. 1782: 401-7. PMID 18381207 DOI: 10.1016/J.Bbadis.2008.02.011  0.662
2008 Carlsson CM, Gleason CE, Hess TM, Moreland KA, Blazel HM, Koscik RL, Schreiber NT, Johnson SC, Atwood CS, Puglielli L, Hermann BP, McBride PE, Stein JH, Sager MA, Asthana S. Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 13: 187-97. PMID 18376061 DOI: 10.3233/Jad-2008-13209  0.374
2008 Atwood CS, Bowen RL. A multi-hit endocrine model of intrinsic adult-onset asthma. Ageing Research Reviews. 7: 114-25. PMID 18373959 DOI: 10.1016/J.Arr.2007.12.002  0.498
2008 Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 28: 466-71. PMID 18282164 DOI: 10.1111/J.1440-1789.2008.00901.X  0.568
2008 Trivedi MA, Schmitz TW, Ries ML, Hess TM, Fitzgerald ME, Atwood CS, Rowley HA, Asthana S, Sager MA, Johnson SC. fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's disease. Neuropsychologia. 46: 1667-78. PMID 18241895 DOI: 10.1016/J.Neuropsychologia.2007.11.035  0.322
2008 Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Fujioka H, Shimohama S, Atwood CS, Petersen RB, Perry G, Smith MA. Oral Presentations OP01: Neurodegenerative Diseases Journal of Neurochemistry. 81: 76-76. DOI: 10.1046/J.1471-4159.81.S1.44_1.X  0.64
2008 Gallego MJ, Porayette P, Kaltcheva MM, Bowen RL, Meethal SV, Atwood CS. Trophoblastic hormones direct early human embryogenesis Nature Precedings. DOI: 10.1038/Npre.2008.2671.1  0.766
2008 Meethal SV, Chan H, Ginsburg E, Wilson AC, Bowen RL, Vonderhaar BK, Atwood CS. P4-220: Identification of a negative feedback loop in the brain for the regulation of neurosteroid synthesis: Implications for Alzheimer's disease Alzheimer's & Dementia. 4: T735-T736. DOI: 10.1016/J.Jalz.2008.05.2288  0.62
2008 Meethal SV, Ockuly JC, Porayette P, Gallego MJ, Haworth RA, Bowen RL, Atwood CS. P3-390: Gonadotropin-releasing hormone signaling in the aging brain: A recapitulation of its role in embryogenesis and its implications for Alzheimer's disease Alzheimer's & Dementia. 4: T635-T636. DOI: 10.1016/J.Jalz.2008.05.1960  0.764
2008 Porayette P, Gallego MJ, Kaltcheva MM, Bowen RL, Meethal SV, Atwood CS. P3-388: Differential processing of amyloid-β precursor protein directs the proliferation and neuronal differentiation of human embryonic stem cells Alzheimer's & Dementia. 4: T635-T635. DOI: 10.1016/J.Jalz.2008.05.1958  0.764
2008 Basson JJ, Wilson AC, Haasl RJ, Atwood CS. P3-199: Multi locus interactions in steroidogenic pathway genes predict Alzheimer's disease Alzheimer's & Dementia. 4: T579-T579. DOI: 10.1016/J.Jalz.2008.05.1765  0.528
2008 Carlsson CM, Barnet J, Blazel HM, Puglielli L, Atwood CS, Gleason CE, Johnson SC, Sager MA, Asthana S. P3-062: Relationship of atherogenic lipid profiles and gender with CSF biomarkers in middle-aged adults at risk for Alzheimer's disease Alzheimer's & Dementia. 4: T535-T535. DOI: 10.1016/J.Jalz.2008.05.1626  0.32
2007 Wilson AC, Meethal SV, Bowen RL, Atwood CS. Leuprolide acetate: a drug of diverse clinical applications. Expert Opinion On Investigational Drugs. 16: 1851-63. PMID 17970643 DOI: 10.1517/13543784.16.11.1851  0.668
2007 Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Report : Communications in Free Radical Research. 12: 257-66. PMID 17961297 DOI: 10.1179/135100007X239270  0.766
2007 Porayette P, Gallego MJ, Kaltcheva MM, Meethal SV, Atwood CS. Amyloid-beta precursor protein expression and modulation in human embryonic stem cells: a novel role for human chorionic gonadotropin. Biochemical and Biophysical Research Communications. 364: 522-7. PMID 17959150 DOI: 10.1016/J.Bbrc.2007.10.021  0.767
2007 Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Current Alzheimer Research. 4: 67-72. PMID 17316167 DOI: 10.2174/156720507779939869  0.79
2007 Liu T, Wimalasena J, Bowen RL, Atwood CS. Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression. Journal of Neurochemistry. 100: 1329-39. PMID 17241129 DOI: 10.1111/J.1471-4159.2006.04307.X  0.563
2007 Atwood CS, Bowen RL. Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes. Medical Hypotheses. 68: 735-49. PMID 17095167 DOI: 10.1016/J.Mehy.2006.08.037  0.518
2007 Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Molecular and Cellular Endocrinology. 260: 271-5. PMID 17052835 DOI: 10.1016/J.Mce.2006.01.018  0.725
2006 Wilson AC, Salamat MS, Haasl RJ, Roche KM, Karande A, Meethal SV, Terasawa E, Bowen RL, Atwood CS. Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression. The Journal of Endocrinology. 191: 651-63. PMID 17170222 DOI: 10.1677/Joe.1.07047  0.662
2006 Vadakkadath Meethal S, Gallego MJ, Haasl RJ, Petras SJ, Sgro JY, Atwood CS. Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditis elegans. Bmc Evolutionary Biology. 6: 103. PMID 17134503 DOI: 10.1186/1471-2148-6-103  0.768
2006 Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. Journal of Biomedicine & Biotechnology. 2006: 39508. PMID 17047306 DOI: 10.1155/Jbb/2006/39508  0.719
2006 Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Molecular Neurodegeneration. 1: 14. PMID 17018137 DOI: 10.1186/1750-1326-1-14  0.728
2006 Strobel G, Smith M, Gandy S, Breitner J, Wise P, Toran-Allerand D, Atwood C, Gregory C, Li R, McAsey M, Brinton R, Barbee J, Struble R, Zandi P, Zhao L, et al. Alzheimer research forum live discussion: Not dead yet: Estrogen deserves another chance Journal of Alzheimer's Disease. 10: 121-130. PMID 16988489 DOI: 10.3233/jad-2006-10116  0.47
2006 Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs in R&D. 7: 187-93. PMID 16752944 DOI: 10.2165/00126839-200607030-00004  0.73
2006 Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA. Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochimica Et Biophysica Acta. 1762: 447-52. PMID 16503402 DOI: 10.1016/J.Bbadis.2006.01.008  0.735
2006 Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Current Pharmaceutical Design. 12: 691-7. PMID 16472159 DOI: 10.2174/138161206775474305  0.731
2006 Gregory CW, Atwood CS, Smith MA, Bowen RL. Antigonadotropins: a novel strategy to halt Alzheimer's disease progression. Current Pharmaceutical Design. 12: 685-90. PMID 16472158 DOI: 10.2174/138161206775474288  0.69
2006 Wilson AC, Salamat MS, Meethal SV, Smith MA, Terasawa E, Bowen RL, Atwood CS. Extrapituitary expression of luteinizing hormone by human neurons possessing GnRH receptor 1 Frontiers in Neuroendocrinology. 27: 87-88. DOI: 10.1016/J.Yfrne.2006.03.190  0.708
2006 Haasl RJ, Marvitz JM, Meethal SV, Gallego MJ, Atwood CS. Endoreduplication in Caenorhabditis elegans: A positive or negative age-related event regulated by hormones? Frontiers in Neuroendocrinology. 27: 74-75. DOI: 10.1016/J.Yfrne.2006.03.155  0.488
2006 Gallego MJ, Meethal SV, Haasl RJ, Sgro JY, Atwood CS. Genomic elements of the hypothalamic-pituitary-gonadal axis in Caenorhabditis elegans Frontiers in Neuroendocrinology. 27: 71-72. DOI: 10.1016/J.Yfrne.2006.03.150  0.465
2006 Meethal SV, Gallego MJ, Haasl RJ, Petras SJ, Sgro JY, Bowen RL, Atwood CS. Identification of a gonadotropin-releasing hormone receptor homologue in Caenorhabditis elegans Frontiers in Neuroendocrinology. 27: 71. DOI: 10.1016/J.Yfrne.2006.03.149  0.515
2006 Webber KM, Casadesus G, Previll LA, Zhu X, Gregory C, Bowen R, Atwood CS, Perry G, Stocco DM, Smith MA. P1-369: Evidence of gonadotropin-induced steroidogenesis in Alzheimer's disease Alzheimer's & Dementia. 2: S206-S206. DOI: 10.1016/J.Jalz.2006.05.747  0.706
2006 Casadesus G, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. P3-296: Luteinizing hormone mediates Alzheimer-type changes in neurons Alzheimer's & Dementia. 2: S462-S462. DOI: 10.1016/J.Jalz.2006.05.1565  0.696
2005 Meethal SV, Smith MA, Bowen RL, Atwood CS. The gonadotropin connection in Alzheimer's disease. Endocrine. 26: 317-26. PMID 16034187 DOI: 10.1385/Endo:26:3:317  0.716
2005 Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Annals of the New York Academy of Sciences. 1052: 201-9. PMID 16024763 DOI: 10.1196/Annals.1347.020  0.719
2005 Gleason CE, Carlsson CM, Johnson S, Atwood C, Asthana S. Clinical pharmacology and differential cognitive efficacy of estrogen preparations Annals of the New York Academy of Sciences. 1052: 93-115. PMID 16024754 DOI: 10.1196/annals.1347.007  0.309
2005 Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? Journal of Alzheimer's Disease : Jad. 7: 247-53; discussion 2. PMID 16006669 DOI: 10.3233/Jad-2005-7308  0.603
2005 Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Disease and Associated Disorders. 19: 95-9. PMID 15942328 DOI: 10.1097/01.Wad.0000165512.90864.3F  0.719
2005 Atwood CS, Meethal SV, Liu T, Wilson AC, Gallego M, Smith MA, Bowen RL. Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence. Journal of Neuropathology and Experimental Neurology. 64: 93-103. PMID 15751223 DOI: 10.1093/Jnen/64.2.93  0.786
2005 Atwood CS, Smith MA, Bowen RL. Feedback on a feedback loop: the hypothalamic-pituitary-gonadal axis. Journal of Alzheimer's Disease : Jad. 7: 1-2. PMID 15750209 DOI: 10.3233/Jad-2005-7101  0.69
2005 Casadesus G, Atwood CS, Zhu X, Hartzler AW, Webber KM, Perry G, Bowen RL, Smith MA. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cellular and Molecular Life Sciences : Cmls. 62: 293-8. PMID 15723165 DOI: 10.1007/S00018-004-4384-0  0.737
2005 Vadakkadath Meethal S, Atwood CS. The role of hypothalamic-pituitary-gonadal hormones in the normal structure and functioning of the brain. Cellular and Molecular Life Sciences : Cmls. 62: 257-70. PMID 15723162 DOI: 10.1007/s00018-004-4381-3  0.768
2005 Bowen RL, Martins RN, Gregory CW, Smith MA, Atwood CS. Dementia and testosterone levels in men. Jama. 293: 551; author reply 55. PMID 15687304 DOI: 10.1001/Jama.293.5.551-B  0.623
2005 Cui Z, Lockman PR, Atwood CS, Hsu CH, Gupte A, Allen DD, Mumper RJ. Novel D-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 59: 263-72. PMID 15661498 DOI: 10.1016/J.Ejpb.2004.07.009  0.341
2004 Huang X, Atwood CS, Moir RD, Hartshorn MA, Tanzi RE, Bush AI. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 954-60. PMID 15578276 DOI: 10.1007/S00775-004-0602-8  0.62
2004 Casadesus G, Zhu X, Atwood CS, Webber KM, Perry G, Bowen RL, Smith MA. Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. Current Drug Targets. Cns and Neurological Disorders. 3: 281-5. PMID 15379604 DOI: 10.2174/1568007043337265  0.741
2004 Bowen RL, Atwood CS. Living and dying for sex. A theory of aging based on the modulation of cell cycle signaling by reproductive hormones. Gerontology. 50: 265-90. PMID 15331856 DOI: 10.1159/000079125  0.535
2004 Verdile G, Fuller S, Atwood CS, Laws SM, Gandy SE, Martins RN. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 50: 397-409. PMID 15304237 DOI: 10.1016/J.Phrs.2003.12.028  0.647
2004 Zhu X, Webber KM, Casadesus G, Raina AK, Lee HG, Marlatt M, Hartzler A, Atwood CS, Perry G, Smith MA. Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities. Current Drug Targets. 5: 559-63. PMID 15270202 DOI: 10.2174/1389450043345317  0.645
2004 Webber KM, Bowen R, Casadesus G, Perry G, Atwood CS, Smith MA. Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection. Acta Neurobiologiae Experimentalis. 64: 113-8. PMID 15190686  0.703
2004 Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. Journal of Neurochemistry. 89: 1233-40. PMID 15147516 DOI: 10.1111/J.1471-4159.2004.02416.X  0.642
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. Journal of Neuroscience Research. 75: 698-703. PMID 14991845 DOI: 10.1002/Jnr.20028  0.709
2004 Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. The Journal of Biological Chemistry. 279: 20539-45. PMID 14871891 DOI: 10.1074/Jbc.M311993200  0.798
2004 Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. Journal of Neurochemistry. 88: 554-63. PMID 14720205 DOI: 10.1046/J.1471-4159.2003.02196.X  0.732
2004 Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 43: 560-8. PMID 14717612 DOI: 10.1021/Bi0358824  0.671
2004 Casadesus G, Webber KM, Ogawa O, Bowen RL, Atwood CS, Perry G, Smith MA. P1-369 Modulation of cognition and amyloid load in the aged SWAβPP transgenic mouse by luprolide acetate, a GNRH agonist: targeting luteinizing hormone as a novel treatment for AD Neurobiology of Aging. 25: S203. DOI: 10.1016/S0197-4580(04)80681-X  0.704
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk J, Shah S, Atwood CS, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80133-7  0.688
2004 Atwood CS, Liu T, Smith MA, Martins RN, Bowen RL, Verdile G. O2-04-06 17β-Estradiol and luteinizing hormone modulate the expression of luteinizing hormone receptors in neuroblastoma cells Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80132-5  0.733
2004 Bowen R, Atwood CS, Perry G, Smith MA. Mechanisms Involved in Gender Differences in Alzheimer's Disease: The Role of Leuteinizing and Follicle Stimulating Hormones Principles of Gender-Specific Medicine. 2: 1234-1237. DOI: 10.1016/B978-012440905-7/50388-1  0.707
2003 Atwood CS, Barzilai N, Bowen RL, Brown-Borg HM, Jarrard DF, Fu VX, Heilbronn LK, Ingram DK, Ravussin E, Schwartz RS, Weindruch R. Pennington scientific symposium on mechanisms and retardation of aging. Experimental Gerontology. 38: 1217-26. PMID 14580876 DOI: 10.1016/J.Exger.2003.08.005  0.505
2003 Atwood CS, Bowen RL, Smith MA, Perry G. Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply. Brain Research. Brain Research Reviews. 43: 164-78. PMID 14499467 DOI: 10.1016/S0165-0173(03)00206-6  0.693
2003 Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN. Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Research. Brain Research Reviews. 43: 1-16. PMID 14499458 DOI: 10.1016/S0165-0173(03)00174-7  0.634
2003 Veurink G, Liu D, Taddei K, Perry G, Smith MA, Robertson TA, Hone E, Groth DM, Atwood CS, Martins RN. Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants. Free Radical Biology & Medicine. 34: 1070-7. PMID 12684092 DOI: 10.1016/S0891-5849(03)00042-X  0.59
2003 Dong J, Atwood CS, Anderson VE, Siedlak SL, Smith MA, Perry G, Carey PR. Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry. 42: 2768-73. PMID 12627941 DOI: 10.1021/Bi0272151  0.633
2003 Smith MA, Perry G, Atwood CS, Bowen RL. Estrogen replacement and risk of Alzheimer disease. Jama. 289: 1100; author reply 1. PMID 12622570 DOI: 10.1001/Jama.289.9.1100-A  0.697
2003 Atwood CS, Perry G, Smith MA. Cerebral hemorrhage and amyloid-beta. Science (New York, N.Y.). 299: 1014; author reply 1. PMID 12586924 DOI: 10.1126/science.299.5609.1014a  0.61
2003 Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 77-81. PMID 12572666 DOI: 10.1023/A:1020731021276  0.626
2002 Reddy VP, Obrenovich ME, Atwood CS, Perry G, Smith MA. Involvement of Maillard reactions in Alzheimer disease. Neurotoxicity Research. 4: 191-209. PMID 12829400 DOI: 10.1080/1029840290007321  0.636
2002 Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiology of Aging. 23: 1097-9. PMID 12470809 DOI: 10.1016/S0197-4580(02)00038-6  0.597
2002 Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. Journal of Neural Transmission. Supplementum. 69-75. PMID 12456052 DOI: 10.1007/978-3-7091-6139-5_7  0.603
2002 Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radical Biology & Medicine. 33: 1475-9. PMID 12446204 DOI: 10.1016/S0891-5849(02)01113-9  0.631
2002 Bishop GM, Robinson SR, Liu Q, Perry G, Atwood CS, Smith MA. Iron: a pathological mediator of Alzheimer disease? Developmental Neuroscience. 24: 184-7. PMID 12401957 DOI: 10.1159/000065696  0.795
2002 Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. Journal of Neuroscience Research. 70: 514-8. PMID 12391612 DOI: 10.1002/Jnr.10452  0.729
2002 Atwood CS, Bishop GM, Perry G, Smith MA. Amyloid-beta: a vascular sealant that protects against hemorrhage? Journal of Neuroscience Research. 70: 356. PMID 12391596 DOI: 10.1002/Jnr.10388  0.756
2002 Atwood CS, Robinson SR, Smith MA. Amyloid-beta: redox-metal chelator and antioxidant. Journal of Alzheimer's Disease : Jad. 4: 203-14. PMID 12226539 DOI: 10.3233/Jad-2002-4310  0.632
2002 Atwood CS, Martins RN, Smith MA, Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides. 23: 1343-50. PMID 12128091 DOI: 10.1016/S0196-9781(02)00070-0  0.624
2002 Rottkamp CA, Atwood CS, Joseph JA, Nunomura A, Perry G, Smith MA. The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides. 23: 1333-41. PMID 12128090 DOI: 10.1016/S0196-9781(02)00069-4  0.629
2002 Smith MA, Atwood CS, Joseph JA, Perry G. Ill-fated amyloid-beta vaccine. Journal of Neuroscience Research. 69: 285. PMID 12125069 DOI: 10.1002/jnr.10316  0.58
2002 Smith MA, Joseph JA, Atwood CS, Perry G. Dangers of the amyloid-beta vaccination. Acta Neuropathologica. 104: 110. PMID 12070672 DOI: 10.1007/s00401-002-0572-2  0.58
2002 Smith MA, Atwood CS, Joseph JA, Perry G. Predicting the failure of amyloid-beta vaccine. Lancet. 359: 1864-5. PMID 12044411 DOI: 10.1016/S0140-6736(02)08695-6  0.611
2002 Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. Cns Drugs. 16: 339-52. PMID 11994023 DOI: 10.2165/00023210-200216050-00006  0.6
2002 Bishop GM, Robinson SR, Smith MA, Perry G, Atwood CS. Call for Elan to publish Alzheimer's trial details. Nature. 416: 677. PMID 11961526 DOI: 10.1038/416677D  0.78
2002 Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochemistry International. 40: 527-31. PMID 11850109 DOI: 10.1016/S0197-0186(01)00123-1  0.632
2001 Fonte J, Miklossy J, Atwood C, Martins R. The severity of cortical Alzheimer's type changes is positively correlated with increased amyloid-beta Levels: Resolubilization of amyloid-beta with transition metal ion chelators. Journal of Alzheimer's Disease : Jad. 3: 209-219. PMID 12214062 DOI: 10.3233/Jad-2001-3206  0.401
2001 Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mechanisms of Ageing and Development. 123: 39-46. PMID 11640950 DOI: 10.1016/S0047-6374(01)00342-6  0.47
2001 Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 759-67. PMID 11487050 DOI: 10.1093/Jnen/60.8.759  0.64
2001 Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radical Biology & Medicine. 31: 175-80. PMID 11440829 DOI: 10.1016/S0891-5849(01)00570-6  0.637
2001 Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 30: 665-76. PMID 11430801 DOI: 10.1016/S0896-6273(01)00317-8  0.675
2001 Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, et al. Mitochondrial abnormalities in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3017-23. PMID 11312286  0.497
2001 Perry G, Avila J, Espey MG, Wink DA, Atwood CS, Smith MA. Biochemistry of neurodegeneration. Science (New York, N.Y.). 291: 595-7. PMID 11229401 DOI: 10.1126/Science.291.5504.595C  0.6
2001 Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA. Redox-active iron mediates amyloid-beta toxicity. Free Radical Biology & Medicine. 30: 447-50. PMID 11182300 DOI: 10.1016/S0891-5849(00)00494-9  0.675
2001 Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PLR, Jones PK, et al. Mitochondrial Abnormalities in Alzheimer's Disease The Journal of Neuroscience. 21: 3017-3023. DOI: 10.1523/Jneurosci.21-09-03017.2001  0.471
2000 Bush AI, Atwood CS, Goldstein LE, Huang X, Rogers J. Could Abeta and AbetaPP be Antioxidants? Journal of Alzheimer's Disease : Jad. 2: 83-84. PMID 12214093 DOI: 10.3233/Jad-2000-2203  0.475
2000 Atwood CS, Scarpa RC, Huang X, Moir RD, Jones WD, Fairlie DP, Tanzi RE, Bush AI. Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. Journal of Neurochemistry. 75: 1219-33. PMID 10936205 DOI: 10.1046/J.1471-4159.2000.0751219.X  0.593
2000 Atwood CS, Huang X, Khatri A, Scarpa RC, Kim YS, Moir RD, Tanzi RE, Roher AE, Bush AI. Copper catalyzed oxidation of Alzheimer Abeta. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 777-83. PMID 10875439  0.574
2000 Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT, Bowden EF, Tanzi RE, Bush AI. 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. Biochemistry. 39: 7266-75. PMID 10852726 DOI: 10.1021/Bi992997S  0.55
2000 Huang X, Cuajungco MP, Atwood CS, Moir RD, Tanzi RE, Bush AI. Alzheimer's disease, beta-amyloid protein and zinc. The Journal of Nutrition. 130: 1488S-92S. PMID 10801964 DOI: 10.1093/Jn/130.5.1488S  0.562
2000 Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. The Journal of Biological Chemistry. 275: 19439-42. PMID 10801774 DOI: 10.1074/jbc.C000165200  0.603
2000 Cuajungco MP, Atwood CS, Huang X, Lynch T, Cherny RA, Perry G, Bush AI. Competitive regulation of aβredox activity by copper and zinc: Parallels in the pathogenetic mechanisms of Alzheimer's disease and familial amyotrophic lateral sclerosis Neurobiology of Aging. 21: 62. DOI: 10.1016/S0197-4580(00)82501-4  0.578
2000 Huang X, Moir RD, Atwood CS, Goldstein LE, Tanzi RE, Bush AI. Enhanced redox interaction of copper-Aβ by homocysteine Neurobiology of Aging. 21: 62. DOI: 10.1016/S0197-4580(00)82500-2  0.579
2000 Atwood CS, Moir RD, Jones WD, Huang X, Perry G, Tanzi RE, Roher AE, Bush AI. Human amyloid-derived aßcontains tyrosine cross-linked oligomers Neurobiology of Aging. 21: 199. DOI: 10.1016/S0197-4580(00)82237-X  0.634
1999 Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, Scarpa RC, Saunders AJ, Lim J, Moir RD, Glabe C, et al. Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. The Journal of Biological Chemistry. 274: 37111-6. PMID 10601271 DOI: 10.1074/Jbc.274.52.37111  0.662
1999 Cherny RA, Legg JT, McLean CA, Fairlie DP, Huang X, Atwood CS, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion. The Journal of Biological Chemistry. 274: 23223-8. PMID 10438495 DOI: 10.1074/Jbc.274.33.23223  0.638
1999 Moir RD, Atwood CS, Huang X, Tanzi RE, Bush AI. Mounting evidence for the involvement of zinc and copper in Alzheimer's disease. European Journal of Clinical Investigation. 29: 569-70. PMID 10411660 DOI: 10.1046/j.1365-2362.1999.00472.x  0.515
1999 Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry. 38: 7609-16. PMID 10386999 DOI: 10.1021/Bi990438F  0.604
1999 Moir RD, Atwood CS, Romano DM, Laurans MH, Huang X, Bush AI, Smith JD, Tanzi RE. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. Biochemistry. 38: 4595-603. PMID 10194381 DOI: 10.1021/Bi982437D  0.562
1999 Atwood CS, Huang X, Moir RD, Tanzi RE, Bush AI. Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease. Metal Ions in Biological Systems. 36: 309-64. PMID 10093929 DOI: 10.1201/9780203747605-10  0.562
1999 Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI. The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction Biochemistry. 38: X-7616.  0.378
1998 Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI. Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. The Journal of Biological Chemistry. 273: 12817-26. PMID 9582309 DOI: 10.1074/Jbc.273.21.12817  0.601
1997 Huang X, Atwood CS, Moir RD, Hartshorn MA, Vonsattel JP, Tanzi RE, Bush AI. Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors. The Journal of Biological Chemistry. 272: 26464-70. PMID 9334223 DOI: 10.1074/Jbc.272.42.26464  0.562
1996 Atwood C, Moir R, Huang X, Bacarra N, Margo L, Glabe C, Tanzi R, Bush A. 527 Modulation of Aβ and mutant aggregation in vitro by zinc and pH Neurobiology of Aging. 17: S131. DOI: 10.1016/S0197-4580(96)80529-X  0.562
1996 Bush A, Atwood C, Huang X, Moir R, Glabe C, Tanzi R. Abnormal homeostasis of pH and Zinc: The prelude for cerebral Aβ amyloid formation? European Neuropsychopharmacology. 6: 20. DOI: 10.1016/S0197-4580(96)80524-0  0.562
1996 Bush A, Atwood C, Huang X, Moir R, Glabe C, Tanzi R. 522 Abnormal homeostasis of pH and zinc: The prelude for cerebral Aβ amyloid formation? Neurobiology of Aging. 17: S130. DOI: 10.1016/S0197-4580(96)80524-0  0.374
Show low-probability matches.