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Eric Batchelor, Ph.D. - Publications

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 So WY, Wong CS, Azubuike UF, Paul CD, Sangsari PR, Gordon PB, Gong H, Maity TK, Lim P, Yang Z, Haryanto CA, Batchelor E, Jenkins LM, Morgan NY, Tanner K. YAP localization mediates mechanical adaptation of human cancer cells during extravasation . Biorxiv : the Preprint Server For Biology. PMID 38076880 DOI: 10.1101/2023.11.14.567015  0.562
2023 Venkatachalapathy H, Yang Z, Azarin SM, Sarkar CA, Batchelor E. Pulsed stimuli entrain p53 to synchronize single cells and modulate cell-fate determination. Biorxiv : the Preprint Server For Biology. PMID 37961090 DOI: 10.1101/2023.10.24.563786  0.665
2023 Venkatachalapathy H, Brzakala C, Batchelor E, Azarin SM, Sarkar CA. Inertial effect of cell state velocity on the quiescence-proliferation fate decision in breast cancer. Biorxiv : the Preprint Server For Biology. PMID 37292599 DOI: 10.1101/2023.05.22.541793  0.339
2022 Hanson RL, Batchelor E. Coordination of MAPK and p53 dynamics in the cellular responses to DNA damage and oxidative stress. Molecular Systems Biology. 18: e11401. PMID 36472304 DOI: 10.15252/msb.202211401  0.453
2021 Yang Z, Hanson RL, Batchelor E. Progress and challenges in understanding the regulation and function of p53 dynamics. Biochemical Society Transactions. PMID 34495325 DOI: 10.1042/BST20210148  0.66
2020 Hanson RL, Batchelor E. Rucaparib Treatment Alters p53 Oscillations in Single Cells to Enhance DNA-Double-Strand-Break-Induced Cell Cycle Arrest. Cell Reports. 33: 108240. PMID 33053351 DOI: 10.1016/j.celrep.2020.108240  0.429
2019 Harton MD, Koh WS, Bunker AD, Singh A, Batchelor E. p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions. Molecular Systems Biology. 15: e8685. PMID 31556489 DOI: 10.15252/Msb.20188685  0.541
2019 Koh WS, Porter JR, Batchelor E. Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations. Scientific Reports. 9: 5976. PMID 30979970 DOI: 10.1038/S41598-019-42509-Y  0.447
2019 Hanson RL, Porter JR, Batchelor E. Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing. The Journal of Cell Biology. PMID 30745421 DOI: 10.1083/Jcb.201803063  0.463
2018 Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Abstract B097: Dysregulated mevalonate and cholesterol synthesis is a therapeutic vulnerability in glioblastoma Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B097  0.354
2017 House CD, Jordan E, Hernandez L, Ozaki M, James JM, Kim M, Kruhlak MJ, Batchelor E, Elloumi F, Cam MC, Annunziata CM. NF-kB promotes ovarian tumorigenesis via classical pathways supporting proliferative cancer cells and alternative pathways supporting ALDH+ cancer stem-like cells. Cancer Research. PMID 29074539 DOI: 10.1158/0008-5472.Can-17-0366  0.342
2017 Batchelor E, Loewer A. Recent progress and open challenges in modeling p53 dynamics in single cells. Current Opinion in Systems Biology. 3: 54-59. PMID 29062976 DOI: 10.1016/J.Coisb.2017.04.007  0.533
2017 Yuen G, Khan FJ, Gao S, Stommel JM, Batchelor E, Wu X, Luo J. CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level. Nucleic Acids Research. PMID 29036671 DOI: 10.1093/Nar/Gkx843  0.316
2017 Porter JR, Fisher BE, Baranello L, Liu JC, Kambach DM, Nie Z, Koh WS, Luo J, Stommel JM, Levens D, Batchelor E. Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response. Molecular Cell. PMID 28867293 DOI: 10.1016/J.Molcel.2017.07.028  0.468
2017 Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Ardori FT, ... ... Batchelor E, et al. Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation. Molecular Cell. PMID 28803781 DOI: 10.1016/J.Molcel.2017.07.013  0.341
2017 Harton MD, Batchelor E. Determining the limitations and benefits of noise in gene regulation and signal transduction through single cell, microscopy-based analysis. Journal of Molecular Biology. PMID 28288800 DOI: 10.1016/J.Jmb.2017.03.007  0.352
2017 Porter JR, Telford WG, Batchelor E. Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards. Journal of Visualized Experiments : Jove. PMID 28287544 DOI: 10.3791/55219  0.354
2017 Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Celiku O, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma. Oncotarget. PMID 28118603 DOI: 10.18632/Oncotarget.14740  0.356
2016 Porter JR, Fisher BE, Batchelor E. p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks. Cell Systems. 2: 272-82. PMID 27135539 DOI: 10.1016/J.Cels.2016.03.006  0.484
2016 Zhou W, Chung YJ, Parrilla Castellar ER, Zheng Y, Chung HJ, Bandle R, Liu J, Tessarollo L, Batchelor E, Aplan PD, Levens D. Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing MYC Expression Levels. The American Journal of Pathology. PMID 26774856 DOI: 10.1016/J.Ajpath.2015.10.028  0.321
2015 Porter JR, Batchelor E. Using computational modeling and experimental synthetic perturbations to probe biological circuits. Methods in Molecular Biology (Clifton, N.J.). 1244: 259-76. PMID 25487101 DOI: 10.1007/978-1-4939-1878-2_12  0.343
2015 Porter JR, Fisher BE, Batchelor E. P53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks Cell Systems. DOI: 10.1016/j.cels.2016.03.006  0.401
2013 Moody AD, Batchelor E. Promoter decoding of transcription factor dynamics. Molecular Systems Biology. 9: 703. PMID 24189398 DOI: 10.1038/Msb.2013.63  0.401
2013 Batchelor E, Kann MG, Przytycka TM, Raphael BJ, Wojtowicz D. Modeling cell heterogeneity: from single-cell variations to mixed cells. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 445-50. PMID 23424148  0.334
2012 Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate. Science (New York, N.Y.). 336: 1440-4. PMID 22700930 DOI: 10.1126/Science.1218351  0.735
2011 Batchelor E, Lahav G. Suppressing variation in synthetic circuits. Molecular Systems Biology. 7: 520. PMID 21811231 DOI: 10.1038/Msb.2011.53  0.647
2011 Batchelor E, Loewer A, Mock C, Lahav G. Stimulus-dependent dynamics of p53 in single cells. Molecular Systems Biology. 7: 488. PMID 21556066 DOI: 10.1038/Msb.2011.20  0.714
2010 Toettcher JE, Mock C, Batchelor E, Loewer A, Lahav G. A synthetic-natural hybrid oscillator in human cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 17047-52. PMID 20837528 DOI: 10.1073/Pnas.1005615107  0.704
2010 Geva-Zatorsky N, Dekel E, Batchelor E, Lahav G, Alon U. Fourier analysis and systems identification of the p53 feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 107: 13550-5. PMID 20622152 DOI: 10.1073/Pnas.1001107107  0.715
2010 Loewer A, Batchelor E, Gaglia G, Lahav G. Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. Cell. 142: 89-100. PMID 20598361 DOI: 10.1016/J.Cell.2010.05.031  0.72
2009 Batchelor E, Loewer A, Lahav G. The ups and downs of p53: understanding protein dynamics in single cells. Nature Reviews. Cancer. 9: 371-7. PMID 19360021 DOI: 10.1038/Nrc2604  0.691
2008 Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. Molecular Cell. 30: 277-89. PMID 18471974 DOI: 10.1016/J.Molcel.2008.03.016  0.686
2006 Batchelor E, Goulian M. Imaging OmpR localization in Escherichia coli Molecular Microbiology. 59: 1767-1778. PMID 16553882 DOI: 10.1111/J.1365-2958.2006.05048.X  0.573
2005 Batchelor E, Walthers D, Kenney LJ, Goulian M. The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins OmpF and OmpC Journal of Bacteriology. 187: 5723-5731. PMID 16077119 DOI: 10.1128/Jb.187.16.5723-5731.2005  0.578
2004 Batchelor E, Silhavy TJ, Goulian M. Continuous control in bacterial regulatory circuits Journal of Bacteriology. 186: 7618-7625. PMID 15516575 DOI: 10.1128/Jb.186.22.7618-7625.2004  0.581
2003 Batchelor E, Goulian M. Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system Proceedings of the National Academy of Sciences of the United States of America. 100: 691-696. PMID 12522261 DOI: 10.1073/Pnas.0234782100  0.579
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