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Richard Olsen - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
GABA-A receptor proteins
Website:
http://faculty.pharmacology.ucla.edu/institution/personnel?personnel_id=46764

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Belelli D, Hales TG, Lambert JJ, Luscher B, Olsen R, Peters JA, Rudolph U, Sieghart W. GABA receptors in GtoPdb v.2021.3. Iuphar/Bps Guide to Pharmacology Cite. 2021. PMID 35005623 DOI: 10.2218/gtopdb/F72/2021.3  0.359
2020 Liu Z, Silva J, Shao AS, Liang J, Wallner M, Shao XM, Li M, Olsen RW. Flavonoid compounds isolated from Tibetan herbs, binding to GABA receptor with anxiolytic property. Journal of Ethnopharmacology. 113630. PMID 33246118 DOI: 10.1016/j.jep.2020.113630  0.583
2019 Olsen RW, Lindemeyer AK, Wallner M, Li X, Huynh KW, Zhou ZH. Cryo-electron microscopy reveals informative details of GABA receptor structural pharmacology: implications for drug discovery. Annals of Translational Medicine. 7: S144. PMID 31576351 DOI: 10.21037/Atm.2019.06.23  0.483
2018 Liu Z, Lindemeyer AK, Liang J, Wallner M, Shao XM, Shao Y, Tao Y, Olsen RW. Flavonoids isolated from Tibetan medicines, binding to GABA receptor and the anticonvulsant activity. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 50: 1-7. PMID 30466968 DOI: 10.1016/J.Phymed.2018.09.198  0.567
2018 Tian J, Dang H, Wallner M, Olsen R, Kaufman DL. Homotaurine, a safe blood-brain barrier permeable GABA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis. Scientific Reports. 8: 16555. PMID 30410049 DOI: 10.1038/S41598-018-32733-3  0.535
2018 Chen J, He Y, Wu Y, Zhou H, Su LD, Li WN, Olsen RW, Liang J, Zhou YD, Shen Y. Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABA Receptors Via PKCδ Activation. Frontiers in Molecular Neuroscience. 11: 141. PMID 29755316 DOI: 10.3389/Fnmol.2018.00141  0.31
2017 Zhang N, Peng Z, Tong X, Kerstin Lindemeyer A, Cetina Y, Huang CS, Olsen RW, Otis TS, Houser CR. Decreased surface expression of the δ subunit of the GABAA receptor contributes to reduced tonic inhibition in dentate granule cells in a mouse model of fragile X syndrome. Experimental Neurology. PMID 28822839 DOI: 10.1016/J.Expneurol.2017.08.008  0.669
2017 Lindemeyer AK, Shen Y, Yazdani F, Shao XM, Spigelman I, Davies DL, Olsen RW, Liang J. Alpha 2 subunit-containing GABAA receptor subtypes are up-regulated and contribute to alcohol-induced functional plasticity in rat hippocampus. Molecular Pharmacology. PMID 28536106 DOI: 10.1124/Mol.116.107797  0.641
2014 Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ. International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands. Pharmacological Reviews. 66: 918-47. PMID 25026896 DOI: 10.1124/Pr.114.008862  0.446
2014 Liang J, Marty VN, Mulpuri Y, Olsen RW, Spigelman I. Selective modulation of GABAergic tonic current by dopamine in the nucleus accumbens of alcohol-dependent rats. Journal of Neurophysiology. 112: 51-60. PMID 24717351 DOI: 10.1152/Jn.00564.2013  0.631
2014 Lindemeyer AK, Liang J, Marty VN, Meyer EM, Suryanarayanan A, Olsen RW, Spigelman I. Ethanol-induced plasticity of GABAA receptors in the basolateral amygdala. Neurochemical Research. 39: 1162-70. PMID 24710789 DOI: 10.1007/S11064-014-1297-Z  0.638
2014 Liang J, Lindemeyer AK, Suryanarayanan A, Meyer EM, Marty VN, Ahmad SO, Shao XM, Olsen RW, Spigelman I. Plasticity of GABA(A) receptor-mediated neurotransmission in the nucleus accumbens of alcohol-dependent rats. Journal of Neurophysiology. 112: 39-50. PMID 24694935 DOI: 10.1152/Jn.00565.2013  0.67
2014 Liang J, Shen Y, Shao XM, Scott MB, Ly E, Wong S, Nguyen A, Tan K, Kwon B, Olsen RW, Spigelman I. Dihydromyricetin prevents fetal alcohol exposure-induced behavioral and physiological deficits: the roles of GABAA receptors in adolescence. Neurochemical Research. 39: 1147-61. PMID 24676702 DOI: 10.1007/S11064-014-1291-5  0.619
2014 Cushman JD, Moore MD, Olsen RW, Fanselow MS. The role of the δ GABA(A) receptor in ovarian cycle-linked changes in hippocampus-dependent learning and memory. Neurochemical Research. 39: 1140-6. PMID 24667980 DOI: 10.1007/S11064-014-1282-6  0.504
2014 Wallner M, Hanchar HJ, Olsen RW. Alcohol selectivity of β3-containing GABAA receptors: evidence for a unique extracellular alcohol/imidazobenzodiazepine Ro15-4513 binding site at the α+β- subunit interface in αβ3δ GABAA receptors. Neurochemical Research. 39: 1118-26. PMID 24500446 DOI: 10.1007/S11064-014-1243-0  0.483
2014 Olsen RW, Li GD, Wallner M, Trudell JR, Bertaccini EJ, Lindahl E, Miller KW, Alkana RL, Davies DL. Structural models of ligand-gated ion channels: sites of action for anesthetics and ethanol. Alcoholism, Clinical and Experimental Research. 38: 595-603. PMID 24164436 DOI: 10.1111/Acer.12283  0.55
2013 Spigelman I, Olsen RW, Liang J, Suryanarayanan A, Lindemeyer AK, Meyer EM, Shen Y, Bagnera R, Marty VN. Molecular and Functional Changes in Receptors: GABA and Chronic Alcohol Consumption Biological Research On Addiction. 219-230. DOI: 10.1016/B978-0-12-398335-0.00023-6  0.653
2012 Gonzalez C, Moss SJ, Olsen RW. Ethanol promotes clathrin adaptor-mediated endocytosis via the intracellular domain of δ-containing GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17874-81. PMID 23223306 DOI: 10.1523/JNEUROSCI.2535-12.2012  0.359
2012 Shen Y, Lindemeyer AK, Gonzalez C, Shao XM, Spigelman I, Olsen RW, Liang J. Dihydromyricetin as a novel anti-alcohol intoxication medication. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 390-401. PMID 22219299 DOI: 10.1523/JNEUROSCI.4639-11.2012  0.655
2011 Suryanarayanan A, Liang J, Meyer EM, Lindemeyer AK, Chandra D, Homanics GE, Sieghart W, Olsen RW, Spigelman I. Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in α4 Subunit Knockout Mice. Frontiers in Neuroscience. 5: 110. PMID 21977012 DOI: 10.3389/Fnins.2011.00110  0.679
2011 Cushman JD, Moore MD, Jacobs NS, Olsen RW, Fanselow MS. Behavioral pharmacogenetic analysis on the role of the α4 GABA(A) receptor subunit in the ethanol-mediated impairment of hippocampus-dependent contextual learning. Alcoholism, Clinical and Experimental Research. 35: 1948-59. PMID 21943327 DOI: 10.1111/J.1530-0277.2011.01546.X  0.554
2011 Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8306-19. PMID 21632951 DOI: 10.1523/Jneurosci.0567-11.2011  0.483
2011 Shen Y, Lindemeyer AK, Spigelman I, Sieghart W, Olsen RW, Liang J. Plasticity of GABAA receptors after ethanol pre-exposure in cultured hippocampal neurons. Molecular Pharmacology. 79: 432-42. PMID 21163967 DOI: 10.1124/Mol.110.068650  0.681
2010 Husain SS, Stewart D, Desai R, Hamouda AK, Li SG, Kelly E, Dostalova Z, Zhou X, Cotten JF, Raines DE, Olsen RW, Cohen JB, Forman SA, Miller KW. p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels. Journal of Medicinal Chemistry. 53: 6432-44. PMID 20704351 DOI: 10.1021/Jm100498U  0.476
2010 Meera P, Olsen RW, Otis TS, Wallner M. Alcohol- and alcohol antagonist-sensitive human GABAA receptors: tracking δ subunit incorporation into functional receptors. Molecular Pharmacology. 78: 918-24. PMID 20699325 DOI: 10.1124/Mol.109.062687  0.764
2010 Li GD, Chiara DC, Cohen JB, Olsen RW. Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors. The Journal of Biological Chemistry. 285: 8615-20. PMID 20083606 DOI: 10.1074/Jbc.M109.074708  0.515
2010 Moore MD, Cushman J, Chandra D, Homanics GE, Olsen RW, Fanselow MS. Trace and contextual fear conditioning is enhanced in mice lacking the alpha4 subunit of the GABA(A) receptor. Neurobiology of Learning and Memory. 93: 383-7. PMID 20018248 DOI: 10.1016/J.Nlm.2009.12.004  0.588
2010 Tanaka M, Delorey TM, Delgado-Escueta AV, Olsen RW. GABRB3, epilepsy, and neurodevelopment Epilepsia. 51: 77. DOI: 10.1111/j.1528-1167.2010.02863.x  0.652
2010 Olsen RW, Spigelman I. GABAA receptor plasticity in alcohol withdrawal Epilepsia. 51: 50. DOI: 10.1111/J.1528-1167.2010.02836.X  0.558
2009 Liang J, Spigelman I, Olsen RW. Tolerance to sedative/hypnotic actions of GABAergic drugs correlates with tolerance to potentiation of extrasynaptic tonic currents of alcohol-dependent rats. Journal of Neurophysiology. 102: 224-33. PMID 19420124 DOI: 10.1152/Jn.90484.2008  0.632
2009 Li GD, Chiara DC, Cohen JB, Olsen RW. Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors. The Journal of Biological Chemistry. 284: 11771-5. PMID 19282280 DOI: 10.1074/Jbc.C900016200  0.523
2009 Meera P, Olsen RW, Otis TS, Wallner M. Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells. Neuropharmacology. 56: 155-60. PMID 18778723 DOI: 10.1016/J.Neuropharm.2008.08.011  0.776
2009 Olsen RW, Sieghart W. GABA A receptors: subtypes provide diversity of function and pharmacology. Neuropharmacology. 56: 141-8. PMID 18760291 DOI: 10.1016/j.neuropharm.2008.07.045  0.362
2009 Collingridge GL, Olsen RW, Peters J, Spedding M. A nomenclature for ligand-gated ion channels. Neuropharmacology. 56: 2-5. PMID 18655795 DOI: 10.1016/j.neuropharm.2008.06.063  0.309
2008 Olsen RW, Sieghart W. International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacological Reviews. 60: 243-60. PMID 18790874 DOI: 10.1124/pr.108.00505  0.375
2008 Wallner M, Olsen RW. Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors as an opportunity for drug development? British Journal of Pharmacology. 154: 288-98. PMID 18278063 DOI: 10.1038/Bjp.2008.32  0.483
2008 Chandra D, Werner DF, Liang J, Suryanarayanan A, Harrison NL, Spigelman I, Olsen RW, Homanics GE. Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice. Alcoholism, Clinical and Experimental Research. 32: 10-8. PMID 18076749 DOI: 10.1111/J.1530-0277.2007.00563.X  0.666
2008 Liang J, Suryanarayanan A, Chandra D, Homanics GE, Olsen RW, Spigelman I. Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells. Alcoholism, Clinical and Experimental Research. 32: 19-26. PMID 18070250 DOI: 10.1111/J.1530-0277.2007.00564.X  0.655
2007 Liang J, Suryanarayanan A, Abriam A, Snyder B, Olsen RW, Spigelman I. Mechanisms of reversible GABAA receptor plasticity after ethanol intoxication. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12367-77. PMID 17989301 DOI: 10.1523/Jneurosci.2786-07.2007  0.684
2007 Olsen RW, Hanchar HJ, Meera P, Wallner M. GABAA receptor subtypes: the "one glass of wine" receptors. Alcohol (Fayetteville, N.Y.). 41: 201-9. PMID 17591543 DOI: 10.1016/J.Alcohol.2007.04.006  0.483
2007 Chen ZW, Chang CS, Leil TA, Olsen RW. C-terminal modification is required for GABARAP-mediated GABA(A) receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6655-63. PMID 17581952 DOI: 10.1523/Jneurosci.0919-07.2007  0.751
2006 Li GD, Chiara DC, Sawyer GW, Husain SS, Olsen RW, Cohen JB. Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11599-605. PMID 17093081 DOI: 10.1523/Jneurosci.3467-06.2006  0.532
2006 Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE. GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol. Proceedings of the National Academy of Sciences of the United States of America. 103: 15230-5. PMID 17005728 DOI: 10.1073/Pnas.0604304103  0.668
2006 Raju R, Rakocevic G, Chen Z, Hoehn G, Semino-Mora C, Shi W, Olsen R, Dalakas MC. Autoimmunity to GABAA-receptor-associated protein in stiff-person syndrome. Brain : a Journal of Neurology. 129: 3270-6. PMID 16984900 DOI: 10.1093/brain/awl245  0.43
2006 Husain SS, Nirthanan S, Ruesch D, Solt K, Cheng Q, Li GD, Arevalo E, Olsen RW, Raines DE, Forman SA, Cohen JB, Miller KW. Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels. Journal of Medicinal Chemistry. 49: 4818-25. PMID 16884293 DOI: 10.1021/Jm051207B  0.473
2006 Wallner M, Hanchar HJ, Olsen RW. Low dose acute alcohol effects on GABA A receptor subtypes. Pharmacology & Therapeutics. 112: 513-28. PMID 16814864 DOI: 10.1016/J.Pharmthera.2006.05.004  0.483
2006 Wallner M, Hanchar HJ, Olsen RW. Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513. Proceedings of the National Academy of Sciences of the United States of America. 103: 8540-5. PMID 16698930 DOI: 10.1073/Pnas.0600194103  0.483
2006 Hanchar HJ, Chutsrinopkun P, Meera P, Supavilai P, Sieghart W, Wallner M, Olsen RW. Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 8546-51. PMID 16581914 DOI: 10.1073/Pnas.0509903103  0.606
2006 Breese GR, Criswell HE, Carta M, Dodson PD, Hanchar HJ, Khisti RT, Mameli M, Ming Z, Morrow AL, Olsen RW, Otis TS, Parsons LH, Penland SN, Roberto M, Siggins GR, et al. Basis of the gabamimetic profile of ethanol. Alcoholism, Clinical and Experimental Research. 30: 731-44. PMID 16573592 DOI: 10.1111/J.0145-6008.2006.00086.X  0.746
2006 Santhakumar V, Hanchar HJ, Wallner M, Olsen RW, Otis TS. Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3357-64. PMID 16554486 DOI: 10.1523/Jneurosci.4799-05.2006  0.77
2006 Elsen FP, Liljelund P, Werner DF, Olsen RW, Homanics GE, Harrison NL. GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice. Brain Research. 1078: 60-70. PMID 16490182 DOI: 10.1016/J.Brainres.2006.01.036  0.353
2006 Liang J, Zhang N, Cagetti E, Houser CR, Olsen RW, Spigelman I. Chronic intermittent ethanol-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1749-58. PMID 16467523 DOI: 10.1523/Jneurosci.4702-05.2006  0.645
2005 Handforth A, Delorey TM, Homanics GE, Olsen RW. Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome. Epilepsia. 46: 1860-70. PMID 16393151 DOI: 10.1111/J.1528-1167.2005.00287.X  0.652
2005 Olsen RW, Liang J, Cagetti E, Spigelman I. Plasticity of GABAA receptors in brains of rats treated with chronic intermittent ethanol. Neurochemical Research. 30: 1579-88. PMID 16362777 DOI: 10.1007/S11064-005-8836-6  0.638
2005 Chen ZW, Chang CS, Leil TA, Olcese R, Olsen RW. GABAA receptor-associated protein regulates GABAA receptor cell-surface number in Xenopus laevis oocytes. Molecular Pharmacology. 68: 152-9. PMID 15814572 DOI: 10.1124/Mol.104.009878  0.767
2005 Hanchar HJ, Dodson PD, Olsen RW, Otis TS, Wallner M. Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity. Nature Neuroscience. 8: 339-45. PMID 15696164 DOI: 10.1038/Nn1398  0.735
2004 Leil TA, Chen ZW, Chang CS, Olsen RW. GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11429-38. PMID 15601949 DOI: 10.1523/Jneurosci.3355-04.2004  0.766
2004 Hanchar HJ, Wallner M, Olsen RW. Alcohol effects on gamma-aminobutyric acid type A receptors: are extrasynaptic receptors the answer? Life Sciences. 76: 1-8. PMID 15501475 DOI: 10.1016/J.Lfs.2004.05.035  0.483
2004 Olsen RW, Chang CS, Li G, Hanchar HJ, Wallner M. Fishing for allosteric sites on GABA(A) receptors. Biochemical Pharmacology. 68: 1675-84. PMID 15451411 DOI: 10.1016/J.Bcp.2004.07.026  0.593
2004 Liang J, Cagetti E, Olsen RW, Spigelman I. Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence. The Journal of Pharmacology and Experimental Therapeutics. 310: 1234-45. PMID 15126642 DOI: 10.1124/Jpet.104.067983  0.655
2004 Everitt AB, Luu T, Cromer B, Tierney ML, Birnir B, Olsen RW, Gage PW. Conductance of recombinant GABA (A) channels is increased in cells co-expressing GABA(A) receptor-associated protein. The Journal of Biological Chemistry. 279: 21701-6. PMID 15007071 DOI: 10.1074/jbc.M312806200  0.309
2003 Wallner M, Hanchar HJ, Olsen RW. Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans. Proceedings of the National Academy of Sciences of the United States of America. 100: 15218-23. PMID 14625373 DOI: 10.1073/Pnas.2435171100  0.483
2003 Spigelman I, Li Z, Liang J, Cagetti E, Samzadeh S, Mihalek RM, Homanics GE, Olsen RW. Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit. Journal of Neurophysiology. 90: 903-10. PMID 12702713 DOI: 10.1152/Jn.01022.2002  0.683
2003 Husain SS, Ziebell MR, Ruesch D, Hong F, Arevalo E, Kosterlitz JA, Olsen RW, Forman SA, Cohen JB, Miller KW. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels. Journal of Medicinal Chemistry. 46: 1257-65. PMID 12646036 DOI: 10.1021/Jm020465V  0.463
2003 Cagetti E, Liang J, Spigelman I, Olsen RW. Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Molecular Pharmacology. 63: 53-64. PMID 12488536 DOI: 10.1124/Mol.63.1.53  0.648
2002 Nymann-Andersen J, Sawyer GW, Olsen RW. Interaction between GABAA receptor subunit intracellular loops: implications for higher order complex formation. Journal of Neurochemistry. 83: 1164-71. PMID 12437587 DOI: 10.1046/J.1471-4159.2002.01222.X  0.349
2002 Sawyer GW, Chiara DC, Olsen RW, Cohen JB. Identification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513. The Journal of Biological Chemistry. 277: 50036-45. PMID 12388542 DOI: 10.1074/Jbc.M209281200  0.491
2002 Nymann-Andersen J, Wang H, Olsen RW. Biochemical identification of the binding domain in the GABA(A) receptor-associated protein (GABARAP) mediating dimer formation. Neuropharmacology. 43: 476-81. PMID 12367594 DOI: 10.1016/S0028-3908(02)00165-X  0.59
2002 Spigelman I, Li Z, Banerjee PK, Mihalek RM, Homanics GE, Olsen RW. Behavior and physiology of mice lacking the GABAA-receptor delta subunit. Epilepsia. 43: 3-8. PMID 12121286 DOI: 10.1046/J.1528-1157.43.S.5.8.X  0.658
2002 Nymann-Andersen J, Wang H, Chen L, Kittler JT, Moss SJ, Olsen RW. Subunit specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors. Journal of Neurochemistry. 80: 815-23. PMID 11948245 DOI: 10.1046/J.0022-3042.2002.00762.X  0.606
2002 Peng Z, Hauer B, Mihalek RM, Homanics GE, Sieghart W, Olsen RW, Houser CR. GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain. The Journal of Comparative Neurology. 446: 179-97. PMID 11932935 DOI: 10.1002/Cne.10210  0.382
2002 Engblom AC, Carlson BX, Olsen RW, Schousboe A, Kristiansen U. Point mutation in the first transmembrane region of the beta 2 subunit of the gamma--aminobutyric acid type A receptor alters desensitization kinetics of gamma--aminobutyric acid- and anesthetic-induced channel gating. The Journal of Biological Chemistry. 277: 17438-47. PMID 11877425 DOI: 10.1074/jbc.M111215200  0.341
2001 Ali NJ, Olsen RW. Chronic benzodiazepine treatment of cells expressing recombinant GABA(A) receptors uncouples allosteric binding: studies on possible mechanisms. Journal of Neurochemistry. 79: 1100-8. PMID 11739624 DOI: 10.1046/J.1471-4159.2001.00664.X  0.754
2001 Kittler JT, Rostaing P, Schiavo G, Fritschy JM, Olsen R, Triller A, Moss SJ. The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors. Molecular and Cellular Neurosciences. 18: 13-25. PMID 11461150 DOI: 10.1006/Mcne.2001.1005  0.477
2001 Petrie J, Sapp DW, Tyndale RF, Park MK, Fanselow M, Olsen RW. Altered gabaa receptor subunit and splice variant expression in rats treated with chronic intermittent ethanol. Alcoholism, Clinical and Experimental Research. 25: 819-28. PMID 11410716 DOI: 10.1111/J.1530-0277.2001.Tb02285.X  0.771
2001 Elster L, Kristiansen U, Pickering DS, Olsen RW, Schousboe A. Molecular determinants of desensitization and assembly of the chimeric GABAA receptor subunits (α1/γ2) and (γ2/α1) in combinations with β2 and γ2 Neurochemistry International. 38: 581-592. PMID 11290383 DOI: 10.1016/S0197-0186(00)00122-4  0.305
2000 Chen L, Wang H, Vicini S, Olsen RW. The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics. Proceedings of the National Academy of Sciences of the United States of America. 97: 11557-62. PMID 10984509 DOI: 10.1073/Pnas.190133497  0.594
2000 Kneussel M, Haverkamp S, Fuhrmann JC, Wang H, Wässle H, Olsen RW, Betz H. The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proceedings of the National Academy of Sciences of the United States of America. 97: 8594-9. PMID 10900017 DOI: 10.1073/Pnas.97.15.8594  0.699
2000 Wang H, Olsen RW. Binding of the GABA(A) receptor-associated protein (GABARAP) to microtubules and microfilaments suggests involvement of the cytoskeleton in GABARAPGABA(A) receptor interaction. Journal of Neurochemistry. 75: 644-55. PMID 10899939 DOI: 10.1046/J.1471-4159.2000.0750644.X  0.571
2000 Gordey M, DeLorey TM, Olsen RW. Differential sensitivity of recombinant GABA(A) receptors expressed in Xenopus oocytes to modulation by topiramate. Epilepsia. 41: S25-9. PMID 10768296  0.652
2000 Carlson BX, Engblom AC, Kristiansen U, Schousboe A, Olsen RW. A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics. Molecular Pharmacology. 57: 474-84. PMID 10692487 DOI: 10.1124/Mol.57.3.474  0.369
1999 Srinivasan S, Sapp DW, Tobin AJ, Olsen RW. Biphasic modulation of GABA(A) receptor binding by steroids suggests functional correlates. Neurochemical Research. 24: 1363-72. PMID 10555776 DOI: 10.1023/A:1022524421464  0.64
1999 Mihalek RM, Banerjee PK, Korpi ER, Quinlan JJ, Firestone LL, Mi ZP, Lagenaur C, Tretter V, Sieghart W, Anagnostaras SG, Sage JR, Fanselow MS, Guidotti A, Spigelman I, Li Z, ... ... Olsen RW, et al. Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 12905-10. PMID 10536021 DOI: 10.1073/Pnas.96.22.12905  0.813
1999 Brandon NJ, Uren JM, Kittler JT, Wang H, Olsen R, Parker PJ, Moss SJ. Subunit-specific association of protein kinase C and the receptor for activated C kinase with GABA type A receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9228-34. PMID 10531426 DOI: 10.1523/Jneurosci.19-21-09228.1999  0.639
1999 DeLorey TM, Olsen RW. GABA and epileptogenesis: comparing gabrb3 gene-deficient mice with Angelman syndrome in man. Epilepsy Research. 36: 123-32. PMID 10515160 DOI: 10.1016/S0920-1211(99)00046-7  0.652
1999 Olsen RW, DeLorey TM, Gordey M, Kang MH. GABA receptor function and epilepsy. Advances in Neurology. 79: 499-510. PMID 10514838  0.652
1999 Lalande M, Minassian BA, DeLorey TM, Olsen RW. Parental imprinting and Angelman syndrome. Advances in Neurology. 79: 421-9. PMID 10514831  0.652
1999 Srinivasan S, Nichols CJ, Lawless GM, Olsen RW, Tobin AJ. Two invariant tryptophans on the alpha1 subunit define domains necessary for GABA(A) receptor assembly. The Journal of Biological Chemistry. 274: 26633-8. PMID 10480864 DOI: 10.1074/Jbc.274.38.26633  0.629
1999 Husain SS, Forman SA, Kloczewiak MA, Addona GH, Olsen RW, Pratt MB, Cohen JB, Miller KW. Synthesis and properties of 3-(2-hydroxyethyl)-3-n-pentyldiazirine, a photoactivable general anesthetic. Journal of Medicinal Chemistry. 42: 3300-7. PMID 10464016 DOI: 10.1021/Jm9806300  0.497
1999 Wang H, Bedford FK, Brandon NJ, Moss SJ, Olsen RW. GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton. Nature. 397: 69-72. PMID 9892355 DOI: 10.1038/16264  0.607
1998 Olsen RW. The molecular mechanism of action of general anesthetics: Structural aspects of interactions with GABA(A) receptors Toxicology Letters. 100: 193-201. PMID 10049142 DOI: 10.1016/S0378-4274(98)00185-4  0.402
1998 Kang MH, Spigelman I, Olsen RW. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. Alcoholism, Clinical and Experimental Research. 22: 2165-73. PMID 9884165 DOI: 10.1111/J.1530-0277.1998.Tb05930.X  0.558
1998 DeLorey TM, Handforth A, Anagnostaras SG, Homanics GE, Minassian BA, Asatourian A, Fanselow MS, Delgado-Escueta A, Ellison GD, Olsen RW. Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8505-14. PMID 9763493 DOI: 10.1523/Jneurosci.18-20-08505.1998  0.775
1998 Minassian BA, DeLorey TM, Olsen RW, Philippart M, Bronstein Y, Zhang Q, Guerrini R, Van Ness P, Livet MO, Delgado-Escueta AV. Angelman syndrome: correlations between epilepsy phenotypes and genotypes. Annals of Neurology. 43: 485-93. PMID 9546330 DOI: 10.1002/ana.410430412  0.644
1998 Miller KW, Addona GH, Cohen JB, Forman SA, Husain SS, Kloczewiak MA, Olsen RW. PROBING ANESTHETIC SITES OF ACTION WITH A NOVEL GENERAL ANESTHETIC; 3,3-AZI-OCTAN-1-OL Anesthesiology. 89: 732A. DOI: 10.1097/00000542-199809130-00038  0.336
1997 Tyndale RF, Bhave SV, Hoffmann E, Hoffmann PL, Tabakoff B, Tobin AJ, Olsen RW. Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation. The Journal of Pharmacology and Experimental Therapeutics. 283: 350-7. PMID 9336343  0.712
1997 Mahmoudi M, Kang MH, Tillakaratne N, Tobin AJ, Olsen RW. Chronic intermittent ethanol treatment in rats increases GABA(A) receptor alpha4-subunit expression: possible relevance to alcohol dependence. Journal of Neurochemistry. 68: 2485-92. PMID 9166743 DOI: 10.1046/j.1471-4159.1997.68062485.x  0.499
1997 Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proceedings of the National Academy of Sciences of the United States of America. 94: 4143-8. PMID 9108119 DOI: 10.1073/Pnas.94.8.4143  0.715
1996 Kang M, Spigelman I, Sapp DW, Olsen RW. Persistent reduction of GABA(A) receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment. Brain Research. 709: 221-8. PMID 8833758 DOI: 10.1016/0006-8993(95)01274-5  0.558
1995 Gordey M, Kang M, Olsen RW, Spigelman I. Zinc modulation of GABAA receptor-mediated chloride flux in rat hippocampal slices. Brain Research. 691: 125-32. PMID 8590044 DOI: 10.1016/0006-8993(95)00653-8  0.558
1995 Greger V, Knoll JH, Woolf E, Glatt K, Tyndale RF, DeLorey TM, Olsen RW, Tobin AJ, Sikela JM, Nakatsu Y. The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3) is tightly linked to the alpha 5 subunit gene (GABRA5) on human chromosome 15q11-q13 and is transcribed in the same orientation. Genomics. 26: 258-64. PMID 7601451 DOI: 10.1016/0888-7543(95)80209-5  0.795
1995 Huh KH, Delorey TM, Endo S, Olsen RW. Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies. Molecular Pharmacology. 48: 666-75. PMID 7476892  0.652
1994 Tyndale RF, Hales TG, Olsen RW, Tobin AJ. Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5417-28. PMID 8083745 DOI: 10.1523/Jneurosci.14-09-05417.1994  0.675
1994 Macdonald RL, Olsen RW. GABAA receptor channels. Annual Review of Neuroscience. 17: 569-602. PMID 7516126 DOI: 10.1146/ANNUREV.NE.17.030194.003033  0.368
1994 Tyndale R, Hales T, Olsen R, Tobin A. Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines The Journal of Neuroscience. 14: 5417-5428. DOI: 10.1523/JNEUROSCI.14-09-05417.1994  0.647
1993 Kim HY, Sapp DW, Olsen RW, Tobin AJ. GABA alters GABAA receptor mRNAs and increases ligand binding. Journal of Neurochemistry. 61: 2334-7. PMID 8245988 DOI: 10.1111/j.1471-4159.1993.tb07481.x  0.499
1992 DeLorey TM, Olsen RW. Gamma-aminobutyric acidA receptor structure and function. The Journal of Biological Chemistry. 267: 16747-50. PMID 1380954  0.652
1991 Endo S, Olsen RW. Subunit and subtype-specific antibodies to the GABA-A/benzodiazepine receptor complex Advances in Experimental Medicine and Biology. 287: 375-380. PMID 1662010 DOI: 10.1007/978-1-4684-5907-4_32  0.344
1991 Tobin AJ, Khrestchatisky M, MacLennan AJ, Chiang MY, Tillakaratne NJ, Xu WT, Jackson MB, Brecha N, Sternini C, Olsen RW. Structural, developmental and functional heterogeneity of rat GABAA receptors. Advances in Experimental Medicine and Biology. 287: 365-74. PMID 1662009 DOI: 10.1007/978-1-4684-5907-4_31  0.504
1991 Olsen RW, Bureau M, Endo S, Smith G, Deng L, Sapp D, Tobin AJ. GABAA-benzodiazepine receptors: demonstration of pharmacological subtypes in the brain. Advances in Experimental Medicine and Biology. 287: 355-64. PMID 1662008 DOI: 10.1007/978-1-4684-5907-4_30  0.499
1990 Olsen RW, Tobin AJ. Molecular biology of GABAA receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 1469-80. PMID 2155149 DOI: 10.1096/fasebj.4.5.2155149  0.499
1988 Olsen RW, Bureau M, Ransom RW, Deng L, Dilber A, Smith G, Krestchatisky M, Tobin AJ. The GABA receptor-chloride ion channel protein complex. Advances in Experimental Medicine and Biology. 236: 1-14. PMID 2467531 DOI: 10.1007/978-1-4757-5971-6_1  0.499
1984 Wong EHF, Snowman AM, Fredrik Leeb-Lundberg LM, Olsen RW. Barbiturates allosterically inhibit GABA antagonist and benzodiazepine inverse agonist binding European Journal of Pharmacology. 102: 205-212. PMID 6090160 DOI: 10.1016/0014-2999(84)90252-8  0.336
1982 Olsen RW. Drug interactions at the GABA receptor-ionophore complex Annual Review of Pharmacology and Toxicology. 22: 245-277. PMID 6282187 DOI: 10.1146/ANNUREV.PA.22.040182.001333  0.311
1981 Leeb-Lundberg F, Snowman A, Olsen RW. Interaction of anticonvulsants with the barbiturate-benzodiazepine-GABA receptor complex. European Journal of Pharmacology. 72: 125-9. PMID 6266847 DOI: 10.1016/0014-2999(81)90309-5  0.346
1981 Leeb-Lundberg F, Snowman A, Olsen RW. Barbiturate receptor sites are coupled to benzodiazepine receptors. Proceedings of the National Academy of Sciences of the United States of America. 77: 7468-72. PMID 6261261 DOI: 10.1073/PNAS.77.12.7468  0.3
1980 Napias C, Bergman MO, Van Ness PC, Greenlee DV, Olsen RW. GABA binding in mammalian brain: inhibition by endogenous GABA. Life Sciences. 27: 1001-11. PMID 7432094 DOI: 10.1016/0024-3205(80)90111-3  0.308
1974 Meunier JC, Sealock R, Olsen R, Changeux JP. Purification and properties of the cholinergic receptor protein from Electrophorus electricus electric tissue. European Journal of Biochemistry / Febs. 45: 371-94. PMID 4853969  0.409
1972 Meunier JC, Olsen RW, Changeux JP. Studies on the cholinergic receptor protein from Electrophorus electricus. Effect of detergents on some hydrodynamic properties of the receptor protein in solution. Febs Letters. 24: 63-8. PMID 5086619  0.443
1972 Meunier JC, Olsen RW, Menez A, Fromageot P, Boquet P, Changeux JP. Some physical properties of the cholinergic receptor protein from Electrophorus electricus revealed by a tritiated alpha-toxin from Naja nigricollis venom. Biochemistry. 11: 1200-10. PMID 5012974 DOI: 10.1021/Bi00757A014  0.449
1972 Olsen RW, Meunier JC, Changeux JP. Progress in the purification of the cholinergic receptor protein from Electrophorus electricus by affinity chromatography. Febs Letters. 28: 96-100. PMID 4646881 DOI: 10.1016/0014-5793(72)80686-0  0.453
1971 Meunier JC, Olsen R, Menez A, Morgat JL, Fromageot P, Ronseray AM, Boquet P, Changeux JP. [Some physical properties of the acetylcholine protein receptor studied with a radioactive neurotoxin]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 273: 595-8. PMID 5001139  0.436
1971 Olsen RW, Ballou CE. Acyl phosphatidylglycerol. A new phospholipid from Salmonella typhimurium. The Journal of Biological Chemistry. 246: 3305-13. PMID 4930058  0.475
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