Lorna Farrelly - Publications

Affiliations: 
2015- Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai, New York, NY, United States 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Stewart AF, Fulton SL, Durand-de Cuttoli R, Thompson RE, Chen PJ, Brindley E, Cetin B, Farrelly LA, Futamura R, Claypool S, Bastle RM, Di Salvo G, Peralta C, Molina H, Baljinnyam E, et al. Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation. Biorxiv : the Preprint Server For Biology. PMID 39345578 DOI: 10.1101/2024.09.19.613951  0.634
2024 Al-Kachak A, Di Salvo G, Fulton SL, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE, et al. Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior. Nature Communications. 15: 5042. PMID 38871707 DOI: 10.1038/s41467-024-49336-4  0.726
2024 Geiger LT, Balouek JA, Farrelly LA, Chen AS, Tang M, Bennett SN, Nestler EJ, Garcia BA, Maze I, Peña CJ. Early-life stress alters chromatin modifications in VTA to prime stress sensitivity. Biorxiv : the Preprint Server For Biology. PMID 38559030 DOI: 10.1101/2024.03.14.584631  0.754
2023 Al-Kachak A, Fulton SL, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Chan JC, Safovich P, Lyu Y, Covington HE, Shen L, et al. Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. Biorxiv : the Preprint Server For Biology. PMID 37205414 DOI: 10.1101/2023.05.04.539464  0.734
2022 Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, et al. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384. PMID 36289231 DOI: 10.1038/s41467-022-34200-0  0.692
2022 Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, et al. Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature Communications. 13: 2195. PMID 35459277 DOI: 10.1038/s41467-022-29922-0  0.685
2021 Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, Liu X, Xu N, Xue Y, Roeder RG, Maze I, Muir TW, Li H. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526675 DOI: 10.1073/pnas.2016742118  0.692
2020 Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806  0.745
2020 Farrelly L, Zhang S, Flaherty E, Topol A, Schrode N, Bastle R, Bhanu N, Garcia B, Li H, Brennand K, Maze I. T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS Schizophrenia Bulletin. 46: S234-S234. DOI: 10.1093/Schbul/Sbaa029.569  0.724
2019 Farrelly LA, Maze I. An emerging perspective on 'histone code' mediated regulation of neural plasticity and disease. Current Opinion in Neurobiology. 59: 157-163. PMID 31382083 DOI: 10.1016/J.Conb.2019.07.001  0.7
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.794
2016 Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/Pnas.1608270113  0.795
2016 Farrelly LA, Dill BD, Molina H, Birtwistle MR, Maze I. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System. Methods in Enzymology. 574: 331-54. PMID 27423867 DOI: 10.1016/Bs.Mie.2016.01.013  0.713
2016 Farrelly LA, Dill BD, Molina H, Birtwistle MR, Maze I. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System Methods in Enzymology. DOI: 10.1016/bs.mie.2016.01.013  0.635
2015 Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/J.Neuron.2015.06.014  0.783
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