Lorna Farrelly - Related publications

Affiliations: 
2015- Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai, New York, NY, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Martire S, Banaszynski LA. The roles of histone variants in fine-tuning chromatin organization and function. Nature Reviews. Molecular Cell Biology. PMID 32665685 DOI: 10.1038/s41580-020-0262-8   
2020 Brownell JE, Allis CD. HAT discovery: Heading toward an elusive goal with a key biological assist. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194605. PMID 32711094 DOI: 10.1016/j.bbagrm.2020.194605   
2020 Kassem S, Ferrari P, Hughes AL, Soudet J, Rando OJ, Strubin M. Histone exchange is associated with activator function at transcribed promoters and with repression at histone loci. Science Advances. 6. PMID 32917590 DOI: 10.1126/sciadv.abb0333   
2020 Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, et al. Histone H3.3 phosphorylation amplifies stimulation-induced transcription. Nature. PMID 32699416 DOI: 10.1038/s41586-020-2533-0   
2020 Francis M, Gopinathan G, Foyle D, Fallah P, Gonzalez M, Luan X, Diekwisch TGH. Histone Methylation: Achilles Heel and Powerful Mediator of Periodontal Homeostasis. Journal of Dental Research. 22034520932491. PMID 32762486 DOI: 10.1177/0022034520932491   
2020 Karthik N, Taneja R. Histone variants in skeletal myogenesis. Epigenetics. 1-20. PMID 32686575 DOI: 10.1080/15592294.2020.1795606   
2020 Lee MK, Kim T. Histone H4-Specific Deacetylation at Active Coding Regions by Hda1C. Molecules and Cells. PMID 32913143 DOI: 10.14348/molcells.2020.0141   
2020 Scott WA, Campos EI. Interactions With Histone H3 & Tools to Study Them. Frontiers in Cell and Developmental Biology. 8: 701. PMID 32850821 DOI: 10.3389/fcell.2020.00701   
2020 Demetriadou C, Koufaris C, Kirmizis A. Histone N-alpha terminal modifications: genome regulation at the tip of the tail. Epigenetics & Chromatin. 13: 29. PMID 32680559 DOI: 10.1186/s13072-020-00352-w   
2020 Jing Y, Ding D, Tian G, Kwan KCJ, Liu Z, Ishibashi T, Li XD. Semisynthesis of site-specifically succinylated histone reveals that succinylation regulates nucleosome unwrapping rate and DNA accessibility. Nucleic Acids Research. PMID 32766790 DOI: 10.1093/nar/gkaa663   
2020 Van Rechem C, Ji F, Mishra S, Chakraborty D, Murphy SE, Dillingham ME, Sadreyev RI, Whetstine JR. The lysine demethylase KDM4A controls the cell-cycle expression of replicative canonical histone genes. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194624. PMID 32798738 DOI: 10.1016/j.bbagrm.2020.194624   
2020 Nacev BA, Jones KB, Intlekofer AM, Yu JSE, Allis CD, Tap WD, Ladanyi M, Nielsen TO. The epigenomics of sarcoma. Nature Reviews. Cancer. PMID 32782366 DOI: 10.1038/s41568-020-0288-4   
2020 Neganova ME, Klochkov SG, Aleksandrova YR, Aliev G. Histone modifications in epigenetic regulation of cancer: perspectives and achieved progress. Seminars in Cancer Biology. PMID 32814115 DOI: 10.1016/j.semcancer.2020.07.015   
2020 Furukawa A, Wakamori M, Arimura Y, Ohtomo H, Tsunaka Y, Kurumizaka H, Umehara T, Nishimura Y. Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in the nucleosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747537 DOI: 10.1073/pnas.2010506117   
2020 Estève PO, Vishnu US, Chin HG, Pradhan S. Visualization and Sequencing of Accessible Chromatin Reveals Cell Cycle and Post Romidepsin Treatment Dynamics. Journal of Molecular Biology. PMID 32763232 DOI: 10.1016/j.jmb.2020.07.023   
2020 Separovich RJ, Pang CNI, Wilkins MR. Controlling the Controllers: Regulation of Histone Methylation by Phosphosignalling. Trends in Biochemical Sciences. PMID 32888772 DOI: 10.1016/j.tibs.2020.08.004   
2020 Waddell AR, Liao D. Assays for Validating Histone Acetyltransferase Inhibitors. Journal of Visualized Experiments : Jove. PMID 32831305 DOI: 10.3791/61289   
2020 Feng Y, Endo M, Sugiyama H. Nucleosomes and epigenetics from a chemical perspective. Chembiochem : a European Journal of Chemical Biology. PMID 32864867 DOI: 10.1002/cbic.202000332   
2020 Kornberg RD, Lorch Y. Primary Role of the Nucleosome. Molecular Cell. 79: 371-375. PMID 32763226 DOI: 10.1016/j.molcel.2020.07.020   
2020 Henn L, Szabó A, Imre L, Román Á, Ábrahám A, Vedelek B, Nánási P, Boros IM. Alternative linker histone permits fast paced nuclear divisions in early Drosophila embryo. Nucleic Acids Research. PMID 32710625 DOI: 10.1093/nar/gkaa624   
2020 Yu J, Xiong C, Zhuo B, Wen Z, Shen J, Liu C, Chang L, Wang K, Wang M, Wu C, Wu X, Xu X, Ruan H, Li G. Analysis of Local Chromatin States Reveals Gene Transcription Potential during Mouse Neural Progenitor Cell Differentiation. Cell Reports. 32: 107953. PMID 32726618 DOI: 10.1016/j.celrep.2020.107953   
2020 Farooqi AA, Fayyaz S, Poltronieri P, Calin G, Mallardo M. Epigenetic deregulation in cancer: Enzyme players and non-coding RNAs. Seminars in Cancer Biology. PMID 32738290 DOI: 10.1016/j.semcancer.2020.07.013   
2020 Jiang D, Borg M, Lorković ZJ, Montgomery SA, Osakabe A, Yelagandula R, Axelsson E, Berger F. The evolution and functional divergence of the histone H2B family in plants. Plos Genetics. 16: e1008964. PMID 32716939 DOI: 10.1371/journal.pgen.1008964   
2020 Espinola Lopez JM, Tan S. The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194629. PMID 32890768 DOI: 10.1016/j.bbagrm.2020.194629   
2020 Li Y, Xia L, Tan K, Ye X, Zuo Z, Li M, Xiao R, Wang Z, Liu X, Deng M, Cui J, Yang M, Luo Q, Liu S, Cao X, et al. N-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2. Nature Genetics. PMID 32778823 DOI: 10.1038/s41588-020-0677-3   
2020 Zhou D, Liu J. Nucleosome movement analysis based on second-order information entropy and density functional theory. Biophysical Chemistry. 265: 106436. PMID 32731086 DOI: 10.1016/j.bpc.2020.106436   
2020 Ferrand J, Plessier A, Polo SE. Control of the chromatin response to DNA damage: Histone proteins pull the strings. Seminars in Cell & Developmental Biology. PMID 32690375 DOI: 10.1016/j.semcdb.2020.07.002   
2020 Agbleke AA, Amitai A, Buenrostro JD, Chakrabarti A, Chu L, Hansen AS, Koenig KM, Labade AS, Liu S, Nozaki T, Ovchinnikov S, Seeber A, Shaban HA, Spille JH, Stephens AD, et al. Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields. Molecular Cell. PMID 32768408 DOI: 10.1016/j.molcel.2020.07.003   
2020 Okuda M, Nishimura Y. The Eaf3 chromodomain acts as a pH sensor for gene expression by altering its binding affinity for histone methylated-lysine residues. Bioscience Reports. 40. PMID 32031206 DOI: 10.1042/BSR20191958   
2020 Sahu RK, Singh S, Tomar RS. The mechanisms of action of chromatin remodelers and implications in development and disease. Biochemical Pharmacology. 114200. PMID 32805211 DOI: 10.1016/j.bcp.2020.114200   
2020 Gorkin DU, Barozzi I, Zhao Y, Zhang Y, Huang H, Lee AY, Li B, Chiou J, Wildberg A, Ding B, Zhang B, Wang M, Strattan JS, Davidson JM, Qiu Y, et al. An atlas of dynamic chromatin landscapes in mouse fetal development. Nature. 583: 744-751. PMID 32728240 DOI: 10.1038/s41586-020-2093-3   
2020 Longbotham JE, Zhang MY, Fujimori DG. Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities. Current Opinion in Chemical Biology. 57: 105-113. PMID 32758979 DOI: 10.1016/j.cbpa.2020.06.001   
2020 McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, et al. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nature Structural & Molecular Biology. PMID 32747783 DOI: 10.1038/s41594-020-0466-9   
2020 Andrés M, García-Gomis D, Ponte I, Suau P, Roque A. Histone H1 Post-Translational Modifications: Update and Future Perspectives. International Journal of Molecular Sciences. 21. PMID 32824860 DOI: 10.3390/ijms21165941   
2020 Downey M. Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194608. PMID 32711095 DOI: 10.1016/j.bbagrm.2020.194608   
2020 Loppin B, Berger F. Histone Variants: The Nexus of Developmental Decisions and Epigenetic Memory. Annual Review of Genetics. PMID 32857637 DOI: 10.1146/annurev-genet-022620-100039   
2020 Wang XF, Xie SM, Guo SM, Su P, Zhou LQ. Dynamic pattern of histone H3 core acetylation in human early embryos. Cell Cycle (Georgetown, Tex.). 1-9. PMID 32794422 DOI: 10.1080/15384101.2020.1806433   
2020 Wijenayake S, Storey KB. Dynamic regulation of histone H3 lysine (K) acetylation and deacetylation during prolonged oxygen deprivation in a champion anaerobe. Molecular and Cellular Biochemistry. PMID 32729004 DOI: 10.1007/s11010-020-03848-x   
2020 Mastoraki A, Schizas D, Vlachou P, Melissaridou NM, Charalampakis N, Fioretzaki R, Kole C, Savvidou O, Vassiliu P, Pikoulis E. Assessment of Synergistic Contribution of Histone Deacetylases in Prognosis and Therapeutic Management of Sarcoma. Molecular Diagnosis & Therapy. PMID 32696211 DOI: 10.1007/s40291-020-00487-2   
2020 Sandholtz SH, MacPherson Q, Spakowitz AJ. Physical modeling of the heritability and maintenance of epigenetic modifications. Proceedings of the National Academy of Sciences of the United States of America. PMID 32778583 DOI: 10.1073/pnas.1920499117   
2020 Millán J, Lesarri A, Fernández JA, Martínez Ruiz R. Exploring epigenetic marks by analysis of non-covalent interactions. Chembiochem : a European Journal of Chemical Biology. PMID 32815664 DOI: 10.1002/cbic.202000380   
2020 Maleszewska M, Steranka A, Smiech M, Kaza B, Pilanc P, Dabrowski M, Kaminska B. Sequential changes in histone modifications shape transcriptional responses underlying microglia polarization by glioma. Glia. PMID 32710676 DOI: 10.1002/glia.23887   
2020 Hildreth AE, Ellison MA, Francette AM, Seraly JM, Lotka LM, Arndt KM. The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription. Elife. 9. PMID 32845241 DOI: 10.7554/eLife.57757   
2020 Markert J, Luger K. Nucleosomes Meet Their Remodeler Match. Trends in Biochemical Sciences. PMID 32917506 DOI: 10.1016/j.tibs.2020.08.010   
2020 Chen D, Chen QY, Wang Z, Zhu Y, Kluz T, Tan W, Li J, Wu F, Fang L, Zhang X, He R, Shen S, Sun H, Zang C, Jin C, et al. Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements. Iscience. 23: 101518. PMID 32920490 DOI: 10.1016/j.isci.2020.101518   
2020 Blessing C, Knobloch G, Ladurner AG. Restraining and unleashing chromatin remodelers - structural information guides chromatin plasticity. Current Opinion in Structural Biology. 65: 130-138. PMID 32693313 DOI: 10.1016/j.sbi.2020.06.008   
2020 Wang JS, Yoon SH, Wein MN. Role of histone deacetylases in bone development and skeletal disorders. Bone. 115606. PMID 32829038 DOI: 10.1016/j.bone.2020.115606   
2020 Huang Y, Dai Y, Zhou Z. Mechanistic and structural insights into histone H2A-H2B chaperone in chromatin regulation. The Biochemical Journal. 477: 3367-3386. PMID 32941645 DOI: 10.1042/BCJ20190852   
2020 Nishio H, Nagano AJ, Ito T, Suzuki Y, Kudoh H. Seasonal plasticity and diel stability of H3K27me3 in natural fluctuating environments. Nature Plants. PMID 32868888 DOI: 10.1038/s41477-020-00757-1   
2020 de Rooij PGH, Perrella G, Kaiserli E, van Zanten M. The diverse and unanticipated roles of Histone deacetylase 9 in coordinating plant development and environmental acclimation. Journal of Experimental Botany. PMID 32687569 DOI: 10.1093/jxb/eraa335