Ashley Lepack - Publications

Affiliations: 
2015- Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai, New York, NY, United States 

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fulton SL, Mitra S, Lepack AE, Martin JA, Stewart AF, Converse J, Hochstetler M, Dietz DM, Maze I. Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35094023 DOI: 10.1038/s41386-022-01279-4  0.665
2020 Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806  0.722
2019 Werner CT, Mitra S, Martin JA, Stewart AF, Lepack AE, Ramakrishnan A, Gobira PH, Wang ZJ, Neve RL, Gancarz AM, Shen L, Maze I, Dietz DM. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science Advances. 5: eaay0351. PMID 31633032 DOI: 10.1126/Sciadv.Aay0351  0.629
2019 Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, et al. Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nature Neuroscience. PMID 31427770 DOI: 10.1038/S41593-019-0462-8  0.673
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.713
2018 Heshmati M, Aleyasin H, Menard C, Christoffel DJ, Flanigan ME, Pfau ML, Hodes GE, Lepack AE, Bicks LK, Takahashi A, Chandra R, Turecki G, Lobo MK, Maze I, Golden SA, et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339486 DOI: 10.1073/Pnas.1719014115  0.642
2018 Lorsch Z, Hamilton P, Lepack A, Mews P, Parise E, Alcantara L, Issler O, Ramakrishnan A, Purushothaman I, Loh YE, McKenzie A, Wang M, Maze I, Zhang B, Shen L, et al. O41. CREB-Zfp189 Interactions Regulate a Resilient-Specific Transcriptional Network in Animal Models of Depression Biological Psychiatry. 83: S125. DOI: 10.1016/J.Biopsych.2018.02.328  0.622
2016 Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/Pnas.1608270113  0.731
2015 Dwyer JM, Maldonado-Avilés JG, Lepack AE, DiLeone RJ, Duman RS. Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 112: 6188-93. PMID 25918363 DOI: 10.1073/Pnas.1505289112  0.319
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