| Year |
Citation |
Score |
| 2022 |
Opie-Martin S, Iacoangeli A, Topp SD, Abel O, Mayl K, Mehta PR, Shatunov A, Fogh I, Bowles H, Limbachiya N, Spargo TP, Al-Khleifat A, Williams KL, Jockel-Balsarotti J, Bali T, ... ... Siddique T, et al. The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration. Nature Communications. 13: 6901. PMID 36371497 DOI: 10.1038/s41467-022-34620-y |
0.322 |
|
| 2020 |
Silani V, Corcia P, Harms MB, Rouleau G, Siddique T, Ticozzi N. Genetics of primary lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 21: 28-34. PMID 33602012 DOI: 10.1080/21678421.2020.1837177 |
0.427 |
|
| 2020 |
Lowry JL, Ryan ÉB, Esengul YT, Siddique N, Siddique T. Intricacies of aetiology in intrafamilial degenerative disease. Brain Communications. 2: fcaa120. PMID 33134917 DOI: 10.1093/braincomms/fcaa120 |
0.791 |
|
| 2020 |
Pytte J, Flynn LL, Anderton RS, Mastaglia FL, Theunissen F, James I, Pfaff A, Koks S, Saunders AM, Bedlack R, Burns DK, Lutz MW, Siddique N, Siddique T, Roses AD, et al. Disease-modifying effects of an structural variant in a predominantly ALS cohort. Neurology. Genetics. 6: e470. PMID 32754644 DOI: 10.1212/Nxg.0000000000000470 |
0.549 |
|
| 2020 |
Wu JJ, Cai A, Greenslade JE, Higgins NR, Fan C, Le NTT, Tatman M, Whiteley AM, Prado MA, Dieriks BV, Curtis MA, Shaw CE, Siddique T, Faull RLM, Scotter EL, et al. ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513711 DOI: 10.1073/pnas.1917371117 |
0.507 |
|
| 2020 |
Pytte J, Anderton RS, Flynn LL, Theunissen F, Jiang L, Pitout I, James I, Mastaglia FL, Saunders AM, Bedlack R, Siddique T, Siddique N, Akkari PA. Association of a structural variant within the gene with amyotrophic lateral sclerosis. Neurology. Genetics. 6: e406. PMID 32185242 DOI: 10.1212/Nxg.0000000000000406 |
0.375 |
|
| 2020 |
Ortega JA, Daley EL, Kour S, Samani M, Tellez L, Smith HS, Hall EA, Esengul YT, Tsai YH, Gendron TF, Donnelly CJ, Siddique T, Savas JN, Pandey UB, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. PMID 32059759 DOI: 10.1016/J.Neuron.2020.01.020 |
0.78 |
|
| 2019 |
Deng S, Feely SME, Shi Y, Zhai H, Zhan L, Siddique T, Deng HX, Shy ME. Incidence and Clinical Features of TRPV4-Linked Axonal Neuropathies in a USA Cohort of Charcot-Marie-Tooth Disease Type 2. Neuromolecular Medicine. PMID 31468327 DOI: 10.1007/s12017-019-08564-4 |
0.435 |
|
| 2019 |
Deng HX, Pericak-Vance MA, Siddique T. Reply to 'TMEM230 variants in Parkinson's disease' and 'Doubts about TMEM230 as a gene for parkinsonism'. Nature Genetics. PMID 30804556 DOI: 10.1038/S41588-019-0355-5 |
0.331 |
|
| 2017 |
Edens BM, Yan J, Deng HX, Siddique T, Ma YC. A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis. Elife. 6. PMID 28463112 DOI: 10.7554/eLife.25453 |
0.386 |
|
| 2017 |
Zhong Y, Wang J, Henderson MJ, Yang P, Hagen BM, Siddique T, Vogel BE, Deng HX, Fang S. Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus. Elife. 6. PMID 28463106 DOI: 10.7554/Elife.23759 |
0.409 |
|
| 2017 |
Kim MJ, Deng HX, Wong YC, Siddique T, Krainc D. The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking. Human Molecular Genetics. PMID 28115417 DOI: 10.1093/Hmg/Ddw413 |
0.302 |
|
| 2017 |
Edens BM, Yan J, Miller N, Deng H, Siddique T, Ma YC. Author response: A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis Elife. DOI: 10.7554/Elife.25453.012 |
0.329 |
|
| 2016 |
Radzicki D, Liu E, Deng HX, Siddique T, Martina M. Early Impairment of Synaptic and Intrinsic Excitability in Mice Expressing ALS/Dementia-Linked Mutant UBQLN2. Frontiers in Cellular Neuroscience. 10: 216. PMID 27703430 DOI: 10.3389/Fncel.2016.00216 |
0.36 |
|
| 2016 |
Simonett JM, Huang R, Siddique N, Farsiu S, Siddique T, Volpe NJ, Fawzi AA. Macular sub-layer thinning and association with pulmonary function tests in Amyotrophic Lateral Sclerosis. Scientific Reports. 6: 29187. PMID 27383525 DOI: 10.1038/Srep29187 |
0.311 |
|
| 2016 |
Lee S, Shang Y, Redmond SA, Urisman A, Tang AA, Li KH, Burlingame AL, Pak RA, Jovičić A, Gitler AD, Wang J, Gray NS, Seeley WW, Siddique T, Bigio EH, et al. Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. Neuron. PMID 27321923 DOI: 10.1016/J.Neuron.2016.05.021 |
0.379 |
|
| 2016 |
Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, ... ... Siddique T, et al. Identification of TMEM230 mutations in familial Parkinson's disease. Nature Genetics. PMID 27270108 DOI: 10.1038/Ng.3589 |
0.789 |
|
| 2016 |
Bali T, Self W, Liu J, Siddique T, Wang LH, Bird TD, Ratti E, Atassi N, Boylan KB, Glass JD, Maragakis NJ, Caress JB, McCluskey LF, Appel SH, Wymer JP, et al. Defining SOD1 ALS natural history to guide therapeutic clinical trial design. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27261500 DOI: 10.1136/Jnnp-2016-313521 |
0.448 |
|
| 2016 |
Yang Y, Zhang L, Lynch DR, Lukas T, Ahmeti K, Sleiman PM, Ryan E, Schadt KA, Newman JH, Deng HX, Siddique N, Siddique T. Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis. Neurology. Genetics. 2: e60. PMID 27123479 DOI: 10.1212/Nxg.0000000000000060 |
0.795 |
|
| 2015 |
Arrat H, Lukas TJ, Siddique T. ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation. Plos One. 10: e0125638. PMID 25955410 DOI: 10.1371/journal.pone.0125638 |
0.415 |
|
| 2015 |
Hartzfeld DE, Siddique N, Victorson D, O'Neill S, Kinsley L, Siddique T. Reproductive decision-making among individuals at risk for familial amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 114-9. PMID 25204983 DOI: 10.3109/21678421.2014.951945 |
0.344 |
|
| 2015 |
Ajroud-Driss S, Fecto F, Ajroud K, Lalani I, Calvo SE, Mootha VK, Deng HX, Siddique N, Tahmoush AJ, Heiman-Patterson TD, Siddique T. Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy. Neurogenetics. 16: 1-9. PMID 25193783 DOI: 10.1007/S10048-014-0421-1 |
0.798 |
|
| 2015 |
Ajroud-Driss S, Siddique T. Sporadic and hereditary amyotrophic lateral sclerosis (ALS). Biochimica Et Biophysica Acta. 1852: 679-684. PMID 25193032 DOI: 10.1016/J.Bbadis.2014.08.010 |
0.49 |
|
| 2014 |
Gallardo G, Barowski J, Ravits J, Siddique T, Lingrel JB, Robertson J, Steen H, Bonni A. An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration. Nature Neuroscience. 17: 1710-9. PMID 25344630 DOI: 10.1038/Nn.3853 |
0.318 |
|
| 2014 |
Fawzi AA, Simonett JM, Purta P, Moss HE, Lowry JL, Deng HX, Siddique N, Sufit R, Bigio EH, Volpe NJ, Siddique T. Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 569-80. PMID 25319030 DOI: 10.3109/21678421.2014.951941 |
0.449 |
|
| 2014 |
Gorrie GH, Fecto F, Radzicki D, Weiss C, Shi Y, Dong H, Zhai H, Fu R, Liu E, Li S, Arrat H, Bigio EH, Disterhoft JF, Martina M, Mugnaini E, ... Siddique T, et al. Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2. Proceedings of the National Academy of Sciences of the United States of America. 111: 14524-9. PMID 25246588 DOI: 10.1073/Pnas.1405741111 |
0.811 |
|
| 2014 |
Fecto F, Esengul YT, Siddique T. Protein recycling pathways in neurodegenerative diseases. Alzheimer's Research & Therapy. 6: 13. PMID 25031631 DOI: 10.1186/alzrt243 |
0.748 |
|
| 2014 |
Koschnitzky JE, Quinlan KA, Lukas TJ, Kajtaz E, Kocevar EJ, Mayers WF, Siddique T, Heckman CJ. Effect of fluoxetine on disease progression in a mouse model of ALS. Journal of Neurophysiology. 111: 2164-76. PMID 24598527 DOI: 10.1152/Jn.00425.2013 |
0.347 |
|
| 2014 |
Lukas TJ, Schiltz GE, Arrat H, Scheidt K, Siddique T. Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression. Bioorganic & Medicinal Chemistry Letters. 24: 1532-7. PMID 24560539 DOI: 10.1016/J.Bmcl.2014.01.078 |
0.467 |
|
| 2014 |
Wang X, Blanchard J, Grundke-Iqbal I, Wegiel J, Deng HX, Siddique T, Iqbal K. Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection. Acta Neuropathologica. 127: 243-56. PMID 24136402 DOI: 10.1007/S00401-013-1175-9 |
0.386 |
|
| 2013 |
Al-Chalabi A, Kwak S, Mehler M, Rouleau G, Siddique T, Strong M, Leigh PN. Genetic and epigenetic studies of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 44-52. PMID 23678879 DOI: 10.3109/21678421.2013.778571 |
0.391 |
|
| 2013 |
Bigio EH, Wu JY, Deng HX, Bit-Ivan EN, Mao Q, Ganti R, Peterson M, Siddique N, Geula C, Siddique T, Mesulam M. Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid. Acta Neuropathologica. 125: 463-5. PMID 23378033 DOI: 10.1007/S00401-013-1089-6 |
0.376 |
|
| 2013 |
Allen JA, Chen R, Ajroud-Driss S, Sufit RL, Heller S, Siddique T, Wolfe L. Gastrostomy tube placement by endoscopy versus radiologic methods in patients with ALS: a retrospective study of complications and outcome. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 308-14. PMID 23286755 DOI: 10.3109/21678421.2012.751613 |
0.324 |
|
| 2013 |
Ahmeti KB, Ajroud-Driss S, Al-Chalabi A, Andersen PM, Armstrong J, Birve A, Blauw HM, Brown RH, Bruijn L, Chen W, Chio A, Comeau MC, Cronin S, Diekstra FP, Soraya Gkazi A, ... ... Siddique T, et al. Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Neurobiology of Aging. 34: 357.e7-19. PMID 22959728 DOI: 10.1016/j.neurobiolaging.2012.07.017 |
0.8 |
|
| 2012 |
Kwan JY, Jeong SY, Van Gelderen P, Deng HX, Quezado MM, Danielian LE, Butman JA, Chen L, Bayat E, Russell J, Siddique T, Duyn JH, Rouault TA, Floeter MK. Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology. Plos One. 7: e35241. PMID 22529995 DOI: 10.1371/Journal.Pone.0035241 |
0.327 |
|
| 2012 |
Fecto F, Siddique T. UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia. Muscle & Nerve. 45: 157-62. PMID 22246868 DOI: 10.1002/mus.23278 |
0.824 |
|
| 2012 |
Fecto F, Siddique T. What is repeated in ALS and FTLD. The Lancet. Neurology. 11: 25-7. PMID 22154784 DOI: 10.1016/S1474-4422(11)70275-7 |
0.8 |
|
| 2012 |
Fecto F, Deng H, Chen W, Hong S, Boycott K, Gorrie G, Siddique N, Yang Y, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen G, Donkervoort S, ... ... Siddique T, et al. UBQLN2 Mutations in ALS and ALS/Dementia: A Genetic, Functional and Histopathological Analysis (S05.006) Neurology. 78: S05.006-S05.006. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S05.006 |
0.83 |
|
| 2012 |
Fecto F, Gorrie G, Zhai H, Radzicki D, Fu R, Liu E, Weiss C, Martina M, Disterhoft J, Mugnaini E, Siddique T, Deng H. Mutant UBQLN2 Transgenic Mice Recapitulate Behavioral, Pathological and Neurophysiological Characteristics of Human Ubiqulinopathy (P05.165) Neurology. 78: P05.165-P05.165. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.165 |
0.76 |
|
| 2012 |
Fecto F, Esengul YT, Deng H, Siddique T. Autophagy Is Impaired by UBQLN2 Mutations Linked to ALS/FTD (P05.164) Neurology. 78: P05.164-P05.164. DOI: 10.1212/wnl.78.1_meetingabstracts.p05.164 |
0.78 |
|
| 2012 |
Allen J, Hall M, Wallery S, Ajroud-Driss S, Armstrong J, McManus C, Cook T, Sufit R, Chrisman H, Wolfe L, Siddique T. Gastrostomy Tube Placement by Endoscopy Versus Radiologic Methods in Patients with ALS: A Retrospective Review of Complications and Outcome (P01.101) Neurology. 78: P01.101-P01.101. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P01.101 |
0.314 |
|
| 2012 |
Ajroud-Driss S, Fecto F, Ajroud K, Siddique T. Mutations in the Nuclear Encoded Novel Mitochondrial Protein CHCHD10 Cause an Autosomal Dominant Mitochondrial Myopathy (IN7-2.002) Neurology. 78: IN7-2.002-IN7-2.002. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In7-2.002 |
0.801 |
|
| 2011 |
Fecto F, Siddique T. SIGMAR1 mutations, genetic heterogeneity at the chromosome 9p locus, and the expanding etiological diversity of amyotrophic lateral sclerosis. Annals of Neurology. 70: 867-70. PMID 22190360 DOI: 10.1002/ana.22648 |
0.809 |
|
| 2011 |
Siddique T, Ajroud-Driss S. Familial amyotrophic lateral sclerosis, a historical perspective. Acta Myologica : Myopathies and Cardiomyopathies : Official Journal of the Mediterranean Society of Myology / Edited by the Gaetano Conte Academy For the Study of Striated Muscle Diseases. 30: 117-20. PMID 22106714 |
0.392 |
|
| 2011 |
Fecto F, Yan J, Vemula SP, Liu E, Yang Y, Chen W, Zheng JG, Shi Y, Siddique N, Arrat H, Donkervoort S, Ajroud-Driss S, Sufit RL, Heller SL, Deng HX, ... Siddique T, et al. SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis. Archives of Neurology. 68: 1440-6. PMID 22084127 DOI: 10.1001/Archneurol.2011.250 |
0.846 |
|
| 2011 |
Fecto F, Siddique T. Making connections: pathology and genetics link amyotrophic lateral sclerosis with frontotemporal lobe dementia. Journal of Molecular Neuroscience : Mn. 45: 663-75. PMID 21901496 DOI: 10.1007/s12031-011-9637-9 |
0.83 |
|
| 2011 |
Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, ... ... Siddique T, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 477: 211-5. PMID 21857683 DOI: 10.1038/Nature10353 |
0.841 |
|
| 2011 |
Deng HX, Bigio EH, Zhai H, Fecto F, Ajroud K, Shi Y, Yan J, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations. Archives of Neurology. 68: 1057-61. PMID 21825243 DOI: 10.1001/Archneurol.2011.178 |
0.834 |
|
| 2011 |
Subramony SH, Ashizawa T, Langford L, McKenna R, Avvaru B, Siddique T, Vedanarayanan V. Confirmation of the severe phenotypic effect of serine at codon 41 of the superoxide dismutase 1 gene. Muscle & Nerve. 44: 499-502. PMID 21755517 DOI: 10.1002/Mus.22117 |
0.51 |
|
| 2011 |
Quinlan KA, Schuster JE, Fu R, Siddique T, Heckman CJ. Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis. The Journal of Physiology. 589: 2245-60. PMID 21486770 DOI: 10.1113/Jphysiol.2010.200659 |
0.335 |
|
| 2011 |
Fecto F, Shi Y, Huda R, Martina M, Siddique T, Deng HX. Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies. The Journal of Biological Chemistry. 286: 17281-91. PMID 21454511 DOI: 10.1074/Jbc.M111.237685 |
0.764 |
|
| 2011 |
Ajroud-Driss S, Deng HX, Siddique T. Recent advances in the genetics of hereditary axonal sensory-motor neuropathies type 2. Current Neurology and Neuroscience Reports. 11: 262-73. PMID 21327736 DOI: 10.1007/S11910-011-0185-Z |
0.352 |
|
| 2011 |
Klein CJ, Shi Y, Fecto F, Donaghy M, Nicholson G, McEntagart ME, Crosby AH, Wu Y, Lou H, McEvoy KM, Siddique T, Deng HX, Dyck PJ. TRPV4 mutations and cytotoxic hypercalcemia in axonal Charcot-Marie-Tooth neuropathies. Neurology. 76: 887-94. PMID 21288981 DOI: 10.1212/Wnl.0B013E31820F2De3 |
0.805 |
|
| 2010 |
Yan J, Deng HX, Siddique N, Fecto F, Chen W, Yang Y, Liu E, Donkervoort S, Zheng JG, Shi Y, Ahmeti KB, Brooks B, Engel WK, Siddique T. Frameshift and novel mutations in FUS in familial amyotrophic lateral sclerosis and ALS/dementia. Neurology. 75: 807-14. PMID 20668259 DOI: 10.1212/Wnl.0B013E3181F07E0C |
0.805 |
|
| 2010 |
Yasser S, Fecto F, Siddique T, Sheikh KA, Athar P. An unusual case of familial ALS and cerebellar ataxia. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 568-70. PMID 20540686 DOI: 10.3109/17482961003636874 |
0.809 |
|
| 2010 |
Deng HX, Zhai H, Bigio EH, Yan J, Fecto F, Ajroud K, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Annals of Neurology. 67: 739-48. PMID 20517935 DOI: 10.1002/Ana.22051 |
0.83 |
|
| 2010 |
Deng HX, Klein CJ, Yan J, Shi Y, Wu Y, Fecto F, Yau HJ, Yang Y, Zhai H, Siddique N, Hedley-Whyte ET, Delong R, Martina M, Dyck PJ, Siddique T. Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4. Nature Genetics. 42: 165-9. PMID 20037587 DOI: 10.1038/Ng.509 |
0.808 |
|
| 2010 |
Zhou J, Yi J, Fu R, Liu E, Siddique T, RÃos E, Deng HX. Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 285: 705-12. PMID 19889637 DOI: 10.1074/Jbc.M109.041319 |
0.341 |
|
| 2010 |
Schüle R, Siddique T, Deng HX, Yang Y, Donkervoort S, Hansson M, Madrid RE, Siddique N, Schöls L, Björkhem I. Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis. Journal of Lipid Research. 51: 819-23. PMID 19812052 DOI: 10.1194/jlr.M002543 |
0.321 |
|
| 2010 |
Fecto F, Deng HX, Siddique T. Discovering the connection between familial and sporadic amyotrophic lateral sclerosis: Pathology trumps genetics Future Neurology. 5: 625-628. DOI: 10.2217/fnl.10.47 |
0.8 |
|
| 2009 |
Jiang M, Schuster JE, Fu R, Siddique T, Heckman CJ. Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15031-8. PMID 19955354 DOI: 10.1523/Jneurosci.0574-09.2009 |
0.325 |
|
| 2009 |
Ajroud-Driss S, Fecto F, Ajroud K, Yang Y, Donkervoort S, Siddique N, Siddique T. A novel de novo MFN2 mutation causing CMT2A with upper motor neuron signs. Neurogenetics. 10: 359-61. PMID 19350291 DOI: 10.1007/S10048-009-0188-Y |
0.793 |
|
| 2009 |
Kwiatkowski TJ, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, ... ... Siddique T, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science (New York, N.Y.). 323: 1205-8. PMID 19251627 DOI: 10.1126/Science.1166066 |
0.516 |
|
| 2009 |
Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP. Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse. Human Molecular Genetics. 18: 1642-51. PMID 19233858 DOI: 10.1093/Hmg/Ddp085 |
0.621 |
|
| 2009 |
Saeed M, Yang Y, Deng HX, Hung WY, Siddique N, Dellefave L, Gellera C, Andersen PM, Siddique T. Age and founder effect of SOD1 A4V mutation causing ALS. Neurology. 72: 1634-9. PMID 19176896 DOI: 10.1212/01.wnl.0000343509.76828.2a |
0.448 |
|
| 2009 |
Lambrechts D, Poesen K, Fernández-Santiago R, Al-Chalabi A, Del Bo R, Van Vught PW, Khan S, Marklund SL, Brockington A, van Marion I, Anneser J, Shaw C, Ludolph AC, Leigh NP, Comi GP, ... ... Siddique T, et al. Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype. Journal of Medical Genetics. 46: 840-6. PMID 18413368 DOI: 10.1136/jmg.2008.058222 |
0.393 |
|
| 2008 |
Siddique N, Siddique T. Genetics of amyotrophic lateral sclerosis. Physical Medicine and Rehabilitation Clinics of North America. 19: 429-39, vii. PMID 18625408 DOI: 10.1016/j.pmr.2008.05.001 |
0.436 |
|
| 2008 |
Frutiger K, Lukas TJ, Gorrie G, Ajroud-Driss S, Siddique T. Gender difference in levels of Cu/Zn superoxide dismutase (SOD1) in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 184-7. PMID 18574763 DOI: 10.1080/17482960801984358 |
0.412 |
|
| 2008 |
Deng HX, Han-Xiang D, Jiang H, Hujun J, Fu R, Ronggen F, Zhai H, Hong Z, Shi Y, Yong S, Liu E, Erdong L, Hirano M, Makito H, Dal Canto MC, ... ... Siddique T, et al. Molecular dissection of ALS-associated toxicity of SOD1 in transgenic mice using an exon-fusion approach. Human Molecular Genetics. 17: 2310-9. PMID 18424447 DOI: 10.1093/HMG/DDN368 |
0.492 |
|
| 2008 |
Siddique T. What is missing in ALS. The Lancet. Neurology. 7: 289-90. PMID 18313987 DOI: 10.1016/S1474-4422(08)70049-8 |
0.391 |
|
| 2008 |
Tsaousidou MK, Ouahchi K, Warner TT, Yang Y, Simpson MA, Laing NG, Wilkinson PA, Madrid RE, Patel H, Hentati F, Patton MA, Hentati A, Lamont PJ, Siddique T, Crosby AH. Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration. American Journal of Human Genetics. 82: 510-5. PMID 18252231 DOI: 10.1016/J.Ajhg.2007.10.001 |
0.362 |
|
| 2008 |
Wang L, Sharma K, Deng HX, Siddique T, Grisotti G, Liu E, Roos RP. Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology. Neurobiology of Disease. 29: 400-8. PMID 18054242 DOI: 10.1016/J.Nbd.2007.10.004 |
0.637 |
|
| 2007 |
Deng HX, Zhai H, Fu R, Shi Y, Gorrie GH, Yang Y, Liu E, Dal Canto MC, Mugnaini E, Siddique T. Distal axonopathy in an alsin-deficient mouse model. Human Molecular Genetics. 16: 2911-20. PMID 17855450 DOI: 10.1093/Hmg/Ddm251 |
0.392 |
|
| 2007 |
Ajroud-Driss S, Saeed M, Khan H, Siddique N, Hung WY, Sufit R, Heller S, Armstrong J, Casey P, Siddique T, Lukas TJ. Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 8: 305-9. PMID 17852022 DOI: 10.1080/17482960701500650 |
0.316 |
|
| 2007 |
Mishra M, Paunesku T, Woloschak GE, Siddique T, Zhu LJ, Lin S, Greco K, Bigio EH. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathologica. 114: 81-94. PMID 17569064 DOI: 10.1007/S00401-007-0240-7 |
0.332 |
|
| 2007 |
Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, ... ... Siddique T, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/Ana.21147 |
0.528 |
|
| 2006 |
Chen W, Saeed M, Mao H, Siddique N, Dellefave L, Hung WY, Deng HX, Sufit RL, Heller SL, Haines JL, Pericak-Vance M, Siddique T. Lack of association of VEGF promoter polymorphisms with sporadic ALS. Neurology. 67: 508-10. PMID 16894118 DOI: 10.1212/01.Wnl.0000227926.42370.04 |
0.337 |
|
| 2006 |
Saeed M, Siddique N, Hung WY, Usacheva E, Liu E, Sufit RL, Heller SL, Haines JL, Pericak-Vance M, Siddique T. Paraoxonase cluster polymorphisms are associated with sporadic ALS. Neurology. 67: 771-6. PMID 16822964 DOI: 10.1212/01.Wnl.0000227187.52002.88 |
0.38 |
|
| 2006 |
Gul A, Hassan MJ, Mahmood S, Chen W, Rahmani S, Naseer MI, Dellefave L, Muhammad N, Rafiq MA, Ansar M, Chishti MS, Ali G, Siddique T, Ahmad W. Genetic studies of autosomal recessive primary microcephaly in 33 Pakistani families: Novel sequence variants in ASPM gene. Neurogenetics. 7: 105-10. PMID 16673149 DOI: 10.1007/s10048-006-0042-4 |
0.392 |
|
| 2006 |
Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 103: 7142-7. PMID 16636275 DOI: 10.1073/Pnas.0602046103 |
0.468 |
|
| 2006 |
Furukawa Y, Fu R, Deng HX, Siddique T, O'Halloran TV. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 7148-53. PMID 16636274 DOI: 10.1073/Pnas.0602048103 |
0.43 |
|
| 2006 |
Lukas TJ, Luo WW, Mao H, Cole N, Siddique T. Informatics-assisted protein profiling in a transgenic mouse model of amyotrophic lateral sclerosis. Molecular & Cellular Proteomics : McP. 5: 1233-44. PMID 16571896 DOI: 10.1074/mcp.M500431-MCP200 |
0.382 |
|
| 2006 |
Vance C, Al-Chalabi A, Ruddy D, Smith BN, Hu X, Sreedharan J, Siddique T, Schelhaas HJ, Kusters B, Troost D, Baas F, de Jong V, Shaw CE. Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. Brain : a Journal of Neurology. 129: 868-76. PMID 16495328 DOI: 10.1093/Brain/Awl030 |
0.497 |
|
| 2006 |
Yan J, Siddique N, Slifer S, Bigio E, Mao H, Chen W, Liu E, Shi Y, Khan S, Haines J, Pericak-Vance M, Siddique T. A Major Novel Locus for ALS/FTD on Chromosome 9p21 and its Pathological Correlates: S61.006 Neurology. 67: 186-186. DOI: 10.1212/01.Wnl.0000234887.27166.69 |
0.547 |
|
| 2005 |
Li X, Rowland LP, Mitsumoto H, Przedborski S, Bird TD, Schellenberg GD, Peskind E, Johnson N, Siddique T, Mesulam MM, Weintraub S, Mastrianni JA. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Annals of Neurology. 58: 858-64. PMID 16315279 DOI: 10.1002/Ana.20646 |
0.428 |
|
| 2005 |
Kuo JJ, Siddique T, Fu R, Heckman CJ. Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice. The Journal of Physiology. 563: 843-54. PMID 15649979 DOI: 10.1113/Jphysiol.2004.074138 |
0.431 |
|
| 2005 |
Faiyaz-Ul-Haque M, Zaidi SH, King LM, Haque S, Patel M, Ahmad M, Siddique T, Ahmad W, Tsui LC, Cohn DH. Fine mapping of the X-linked split-hand/split-foot malformation (SHFM2) locus to a 5.1-Mb region on Xq26.3 and analysis of candidate genes. Clinical Genetics. 67: 93-7. PMID 15617554 DOI: 10.1111/j.1399-0004.2004.00369.x |
0.386 |
|
| 2004 |
Li YJ, Pericak-Vance MA, Haines JL, Siddique N, McKenna-Yasek D, Hung WY, Sapp P, Allen CI, Chen W, Hosler B, Saunders AM, Dellefave LM, Brown RH, Siddique T. Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis. Neurogenetics. 5: 209-13. PMID 15657798 DOI: 10.1007/S10048-004-0193-0 |
0.416 |
|
| 2004 |
Morris HR, Steele JC, Crook R, Wavrant-De Vrièze F, Onstead-Cardinale L, Gwinn-Hardy K, Wood NW, Farrer M, Lees AJ, McGeer PL, Siddique T, Hardy J, Perez-Tur J. Genome-wide analysis of the parkinsonism-dementia complex of Guam. Archives of Neurology. 61: 1889-97. PMID 15596609 DOI: 10.1001/Archneur.61.12.1889 |
0.356 |
|
| 2004 |
Bigio EH, Johnson NA, Rademaker AW, Fung BB, Mesulam MM, Siddique N, Dellefave L, Caliendo J, Freeman S, Siddique T. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 63: 801-11. PMID 15330335 DOI: 10.1093/Jnen/63.8.801 |
0.409 |
|
| 2004 |
Henkel JS, Engelhardt JI, Siklós L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Annals of Neurology. 55: 221-35. PMID 14755726 DOI: 10.1002/Ana.10805 |
0.353 |
|
| 2004 |
Kuo JJ, Schonewille M, Siddique T, Schults AN, Fu R, Bär PR, Anelli R, Heckman CJ, Kroese AB. Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. Journal of Neurophysiology. 91: 571-5. PMID 14523070 DOI: 10.1152/Jn.00665.2003 |
0.39 |
|
| 2003 |
Rezania K, Yan J, Dellefave L, Deng HX, Siddique N, Pascuzzi RT, Siddique T, Roos RP. A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 4: 162-6. PMID 13129803 DOI: 10.1080/Aml.4.3.162.166 |
0.668 |
|
| 2003 |
El Euch-Fayache G, Lalani I, Amouri R, Turki I, Ouahchi K, Hung WY, Belal S, Siddique T, Hentati F. Phenotypic features and genetic findings in sacsin-related autosomal recessive ataxia in Tunisia. Archives of Neurology. 60: 982-8. PMID 12873855 DOI: 10.1001/Archneur.60.7.982 |
0.417 |
|
| 2003 |
Sapp PC, Hosler BA, McKenna-Yasek D, Chin W, Gann A, Genise H, Gorenstein J, Huang M, Sailer W, Scheffler M, Valesky M, Haines JL, Pericak-Vance M, Siddique T, Horvitz HR, et al. Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. American Journal of Human Genetics. 73: 397-403. PMID 12858291 DOI: 10.1086/377158 |
0.538 |
|
| 2003 |
Ruddy DM, Parton MJ, Al-Chalabi A, Lewis CM, Vance C, Smith BN, Leigh PN, Powell JF, Siddique T, Meyjes EP, Baas F, de Jong V, Shaw CE. Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q. American Journal of Human Genetics. 73: 390-6. PMID 12840784 DOI: 10.1086/377157 |
0.458 |
|
| 2003 |
Aksoy H, Dean G, Elian M, Deng HX, Deng G, Juneja T, Storey E, McKinlay Gardner RJ, Jacob RL, Laing NG, Siddique T. A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis. Neuroepidemiology. 22: 235-8. PMID 12792143 DOI: 10.1159/000070564 |
0.448 |
|
| 2002 |
Jonsson PA, Bäckstrand A, Andersen PM, Jacobsson J, Parton M, Shaw C, Swingler R, Shaw PJ, Robberecht W, Ludolph AC, Siddique T, Skvortsova VI, Marklund SL. CuZn-superoxide dismutase in D90A heterozygotes from recessive and dominant ALS pedigrees. Neurobiology of Disease. 10: 327-33. PMID 12270693 DOI: 10.1006/nbdi.2002.0508 |
0.487 |
|
| 2002 |
Faiyaz-Ul-Haque M, Ahmad W, Wahab A, Haque S, Azim AC, Zaidi SH, Teebi AS, Ahmad M, Cohn DH, Siddique T, Tsui LC. Frameshift mutation in the cartilage-derived morphogenetic protein 1 (CDMP1) gene and severe acromesomelic chondrodysplasia resembling Grebe-type chondrodysplasia. American Journal of Medical Genetics. 111: 31-7. PMID 12124730 DOI: 10.1002/ajmg.10501 |
0.392 |
|
| 2001 |
Cox PR, Siddique T, Zoghbi HY. Genomic organization of Tropomodulins 2 and 4 and unusual intergenic and intraexonic splicing of YL-1 and Tropomodulin 4. Bmc Genomics. 2: 7. PMID 11716785 DOI: 10.1186/1471-2164-2-7 |
0.375 |
|
| 2001 |
Yang Y, Hentati A, Deng HX, Dabbagh O, Sasaki T, Hirano M, Hung WY, Ouahchi K, Yan J, Azim AC, Cole N, Gascon G, Yagmour A, Ben-Hamida M, Pericak-Vance M, ... ... Siddique T, et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nature Genetics. 29: 160-5. PMID 11586297 DOI: 10.1038/Ng1001-160 |
0.482 |
|
| 2000 |
Gaudette M, Hirano M, Siddique T. Current status of SOD1 mutations in familial amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 83-9. PMID 11467054 DOI: 10.1080/14660820050515377 |
0.487 |
|
| 2000 |
Deng HX, Siddique T. Transgenic mouse models and human neurodegenerative disorders. Archives of Neurology. 57: 1695-702. PMID 11115235 DOI: 10.1001/Archneur.57.12.1695 |
0.327 |
|
| 2000 |
Hentati A, Deng HX, Zhai H, Chen W, Yang Y, Hung WY, Azim AC, Bohlega S, Tandan R, Warner C, Laing NG, Cambi F, Mitsumoto H, Roos RP, Boustany RM, ... ... Siddique T, et al. Novel mutations in spastin gene and absence of correlation with age at onset of symptoms. Neurology. 55: 1388-90. PMID 11087788 DOI: 10.1212/Wnl.55.9.1388 |
0.656 |
|
| 2000 |
Hosler BA, Siddique T, Sapp PC, Sailor W, Huang MC, Hossain A, Daube JR, Nance M, Fan C, Kaplan J, Hung WY, McKenna-Yasek D, Haines JL, Pericak-Vance MA, Horvitz HR, et al. Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22. Jama. 284: 1664-9. PMID 11015796 DOI: 10.1001/Jama.284.13.1664 |
0.459 |
|
| 2000 |
Hirano M, Hung WY, Cole N, Azim AC, Deng HX, Siddique T. Multiple transcripts of the human Cu,Zn superoxide dismutase gene. Biochemical and Biophysical Research Communications. 276: 52-6. PMID 11006081 DOI: 10.1006/bbrc.2000.3427 |
0.434 |
|
| 2000 |
Said Ahmed M, Hung WY, Zu JS, Hockberger P, Siddique T. Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. Journal of the Neurological Sciences. 176: 88-94. PMID 10930589 DOI: 10.1016/S0022-510X(00)00317-8 |
0.457 |
|
| 1999 |
Cole N, Siddique T. Genetic disorders of motor neurons. Seminars in Neurology. 19: 407-18. PMID 10716663 DOI: 10.1055/s-2008-1040855 |
0.372 |
|
| 1999 |
Pérez-Tur J, Buée L, Morris HR, Waring SC, Onstead L, Wavrant-De Vrièze F, Crook R, Buée-Scherrer V, Hof PR, Petersen RC, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, et al. Neurodegenerative diseases of Guam: analysis of TAU. Neurology. 53: 411-3. PMID 10430438 DOI: 10.1212/Wnl.53.2.411 |
0.403 |
|
| 1998 |
Siddique T, Pericak-Vance MA, Caliendo J, Hong ST, Hung WY, Kaplan J, McKenna-Yasek D, Rimmler JB, Sapp P, Saunders AM, Scott WK, Siddique N, Haines JL, Brown RH. Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. Neurogenetics. 1: 213-6. PMID 10737125 DOI: 10.1007/S100480050031 |
0.431 |
|
| 1998 |
Hentati A, Ouahchi K, Pericak-Vance MA, Nijhawan D, Ahmad A, Yang Y, Rimmler J, Hung W, Schlotter B, Ahmed A, Ben Hamida M, Hentati F, Siddique T. Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers. Neurogenetics. 2: 55-60. PMID 9933301 DOI: 10.1007/S100480050052 |
0.364 |
|
| 1998 |
Al-Chalabi A, Andersen PM, Chioza B, Shaw C, Sham PC, Robberecht W, Matthijs G, Camu W, Marklund SL, Forsgren L, Rouleau G, Laing NG, Hurse PV, Siddique T, Leigh PN, et al. Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: evidence for a linked protective factor. Human Molecular Genetics. 7: 2045-50. PMID 9817920 DOI: 10.1093/Hmg/7.13.2045 |
0.494 |
|
| 1997 |
Zu JS, Deng HX, Lo TP, Mitsumoto H, Ahmed MS, Hung WY, Cai ZJ, Tainer JA, Siddique T. Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis. Neurogenetics. 1: 65-71. PMID 10735277 DOI: 10.1007/S100480050010 |
0.424 |
|
| 1997 |
Siddique T, Nijhawan D, Hentati A. Familial amyotrophic lateral sclerosis. Journal of Neural Transmission. Supplementum. 49: 219-33. PMID 9266431 DOI: 10.1007/978-3-7091-6844-8_23 |
0.527 |
|
| 1997 |
Isozumi K, DeLong R, Kaplan J, Hung WY, Siddique T. Exclusion of the expansion of CAG/CTG repeats at thirteen loci on chromosome 12 as a candidate genetic mutation in scapuloperoneal spinal muscular atrophy with anticipation. Human Genetics. 99: 701-3. PMID 9187660 DOI: 10.1007/s004390050435 |
0.421 |
|
| 1997 |
Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ, Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology. 41: 497-504. PMID 9124807 DOI: 10.1002/Ana.410410413 |
0.394 |
|
| 1997 |
Ahmed MS, Afsar S, Hentati A, Ahmad A, Pasha J, Juneja T, Hung WY, Ahmad A, Choudhri A, Saya S, Siddique T. A novel mutation in the sterol 27-hydroxylase gene of a Pakistani family with autosomal recessive cerebrotendinous xanthomatosis. Neurology. 48: 258-60. PMID 9008528 DOI: 10.1212/Wnl.48.1.258 |
0.44 |
|
| 1997 |
Juneja T, Pericak-Vance MA, Laing NG, Dave S, Siddique T. Prognosis in familial amyotrophic lateral sclerosis: progression and survival in patients with glu100gly and ala4val mutations in Cu,Zn superoxide dismutase. Neurology. 48: 55-7. PMID 9008494 DOI: 10.1212/Wnl.48.1.55 |
0.487 |
|
| 1996 |
Siddique T. ALS: molecular clues to the jigsaw puzzle of neuronal degeneration. Cold Spring Harbor Symposia On Quantitative Biology. 61: 699-708. PMID 9246496 DOI: 10.1101/Sqb.1996.061.01.070 |
0.367 |
|
| 1996 |
Siddique T, Deng HX. Genetics of amyotrophic lateral sclerosis. Human Molecular Genetics. 5: 1465-70. PMID 8875253 DOI: 10.1093/Hmg/5.Supplement_1.1465 |
0.503 |
|
| 1996 |
Isozumi K, DeLong R, Kaplan J, Deng HX, Iqbal Z, Hung WY, Wilhelmsen KC, Hentati A, Pericak-Vance MA, Siddique T. Linkage of scapuloperoneal spinal muscular atrophy to chromosome 12q24.1-q24.31. Human Molecular Genetics. 5: 1377-82. PMID 8872481 DOI: 10.1093/Hmg/5.9.1377 |
0.323 |
|
| 1996 |
Siddique T, Nijhawan D, Hentati A. Molecular genetic basis of familial ALS. Neurology. 47: S27-34; discussion S. PMID 8858048 DOI: 10.1212/Wnl.47.4_Suppl_2.27S |
0.535 |
|
| 1996 |
Shibata N, Hirano A, Kobayashi M, Siddique T, Deng HX, Hung WY, Kato T, Asayama K. Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. Journal of Neuropathology and Experimental Neurology. 55: 481-90. PMID 8786408 DOI: 10.1097/00005072-199604000-00011 |
0.412 |
|
| 1996 |
Fink JK, Heiman-Patterson T, Bird T, Cambi F, Dubé MP, Figlewicz DA, Fink JK, Haines JL, Heiman-Patterson T, Hentati A, Pericak-Vance MA, Raskind W, Rouleau GA, Siddique T. Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group. Neurology. 46: 1507-14. PMID 8649538 DOI: 10.1212/Wnl.46.6.1507 |
0.378 |
|
| 1996 |
Hentati A, Deng HX, Hung WY, Nayer M, Ahmed MS, He X, Tim R, Stumpf DA, Siddique T, Ahmed. Human alpha-tocopherol transfer protein: gene structure and mutations in familial vitamin E deficiency. Annals of Neurology. 39: 295-300. PMID 8602747 DOI: 10.1002/Ana.410390305 |
0.421 |
|
| 1995 |
Siddique T, Hentati A. Familial amyotrophic lateral sclerosis. Clinical Neuroscience (New York, N.Y.). 3: 338-47. PMID 9021255 |
0.437 |
|
| 1995 |
Gascon GG, Chavis P, Yaghmour A, Stigsby B, Shums A, Ozand P, Siddique T. Familial childhood primary lateral sclerosis with associated gaze paresis. Neuropediatrics. 26: 313-9. PMID 8719747 DOI: 10.1055/s-2007-979781 |
0.319 |
|
| 1995 |
Deng HX, Tainer JA, Mitsumoto H, Ohnishi A, He X, Hung WY, Zhao Y, Juneja T, Hentati A, Siddique T. Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis. Human Molecular Genetics. 4: 1113-6. PMID 7655471 DOI: 10.1093/Hmg/4.6.1113 |
0.46 |
|
| 1995 |
Själander A, Beckman G, Deng HX, Iqbal Z, Tainer JA, Siddique T. The D90A mutation results in a polymorphism of Cu,Zn superoxide dismutase that is prevalent in northern Sweden and Finland. Human Molecular Genetics. 4: 1105-8. PMID 7655469 DOI: 10.1093/Hmg/4.6.1105 |
0.311 |
|
| 1995 |
Roos RR, Siddique T, Tainer JA. Summary of `Superoxide Dismutase (SOD) and Free Radicals in Amyotrophic Lateral Sclerosis and Neurodegeneration' conference Neurology. 45: 1779-1780. DOI: 10.1212/WNL.45.9.1779 |
0.472 |
|
| 1994 |
Mérette C, Brzustowicz LM, Daniels RJ, Davies KE, Gilliam TC, Melki J, Munnich A, Pericak-Vance MA, Siddique T, Voosen B. An investigation of genetic heterogeneity and linkage disequilibrium in 161 families with spinal muscular atrophy. Genomics. 21: 27-33. PMID 8088801 DOI: 10.1006/Geno.1994.1220 |
0.353 |
|
| 1993 |
Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 362: 59-62. PMID 8446170 DOI: 10.1038/362059a0 |
0.394 |
|
| 1993 |
Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP, Warner C, Deng G, Soriano E, Smyth C, Parge HE, ... ... Siddique T, et al. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase Science. 261: 1047-1051. PMID 8351519 DOI: 10.1126/Science.8351519 |
0.684 |
|
| 1992 |
Appelbaum JS, Roos RP, Salazar-Grueso EF, Buchman A, Iannaccone S, Glantz R, Siddique T, Maselli R. Intrafamilial heterogeneity in hereditary motor neuron disease. Neurology. 42: 1488-92. PMID 1641141 DOI: 10.1212/Wnl.42.8.1488 |
0.637 |
|
| 1992 |
DeLong R, Siddique T. A large New England kindred with autosomal dominant neurogenic scapuloperoneal amyotrophy with unique features. Archives of Neurology. 49: 905-8. PMID 1520078 DOI: 10.1001/Archneur.1992.00530330027010 |
0.337 |
|
| 1991 |
Siddique T, Figlewicz DA, Pericak-Vance MA, Haines JL, Rouleau G, Jeffers AJ, Sapp P, Hung WY, Bebout J, McKenna-Yasek D. Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity. The New England Journal of Medicine. 324: 1381-4. PMID 2020294 DOI: 10.1056/Nejm199105163242001 |
0.437 |
|
| 1991 |
Eldridge R, Alberstone C, Meyer MA, Siddique T, Brown RH. Genetic basis of familial amyotrophic lateral sclerosis The New England Journal of Medicine. 325: 1382-1383. PMID 1922244 DOI: 10.1056/Nejm199111073251915 |
0.383 |
|
| 1991 |
Alberts MJ, Kandt RS, Pericak-Vance MA, Bebout J, Speer MC, Siddique TS, Yamaoka L, Hung WY, Gaskell PC, Roses AD. MspI RFLP for microtubule associated protein-2 (MAP2). Nucleic Acids Research. 19: 960. PMID 1708129 DOI: 10.1093/Nar/19.4.960 |
0.357 |
|
| 1989 |
Sarfarazi M, Upadhyaya M, Padberg G, Pericak-Vance M, Siddique T, Lucotte G, Lunt P. An exclusion map for facioscapulohumeral (Landouzy-Déjérine) disease. Journal of Medical Genetics. 26: 481-4. PMID 2769720 DOI: 10.1136/Jmg.26.8.481 |
0.309 |
|
| 1989 |
Siddique T, Pericak-Vance MA, Brooks BR, Roos RP, Hung WY, Antel JP, Munsat TL, Phillips K, Warner K, Speer M. Linkage analysis in familial amyotrophic lateral sclerosis. Neurology. 39: 919-25. PMID 2739919 DOI: 10.1212/Wnl.39.7.919 |
0.62 |
|
| 1989 |
Laing NG, Siddique T, Bartlett R, Yamaoka LH, Hung WY, Pericak-Vance MA, Roses AD. Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry. Clinical Genetics. 35: 393-8. PMID 2736788 DOI: 10.1111/J.1399-0004.1989.Tb02963.X |
0.513 |
|
| 1989 |
Siddique T, Roper H, Pericak-Vance MA, Shaw J, Warner KL, Hung WY, Phillips KL, Lunt P, Cumming WJ, Roses AD. Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease. Journal of Medical Genetics. 26: 487-9. PMID 2570155 DOI: 10.1136/Jmg.26.8.487 |
0.535 |
|
| 1989 |
Siddique T, Phillips K, Betz H, Grenningloh G, Warner K, Hung WY, Laing N, Roses AD. RFLPs of the gene for the human glycine receptor on the X-chromosome. Nucleic Acids Research. 17: 1785. PMID 2564191 DOI: 10.1093/Nar/17.4.1785 |
0.432 |
|
| 1988 |
Bartlett RJ, Pericak-Vance MA, Koh J, Yamaoka LH, Chen JC, Hung WY, Speer MC, Wapenaar MC, Van Ommen GJB, Bakker E, Pearson PL, Kandt RS, Siddique T, Gilbert JR, Lee JE, et al. Duchenne muscular dystrophy: High frequency of deletions Neurology. 38: 1-4. PMID 3275902 DOI: 10.1212/Wnl.38.1.1 |
0.493 |
|
| 1988 |
Siddique T, Bartlett R, Pericak-Vance M, Yamaoka L, Koh J, Chen J, Hung WY, Kandt R, Roses AD. Update on the molecular genetics of Duchenne muscular dystrophy. Australian Paediatric Journal. 24: 9-14. PMID 3060079 |
0.438 |
|
| 1988 |
Walker AP, Bartlett RJ, Laing NG, Siddique T, Yamaoka LH, Chen JC, Hung WY, Roses AD. RFLP for Duchenne muscular dystrophy cDNA clone 30-2. Nucleic Acids Research. 16: 9072. PMID 2902573 DOI: 10.1093/Nar/16.18.9072 |
0.437 |
|
| 1988 |
Laing NG, Siddique T, Bartlett RJ, Yamaoka LH, Chen JC, Walker AP, Hung WY, Roses AD. RFLP for Duchenne muscular dystrophy cDNA clone 44-1. Nucleic Acids Research. 16: 7209. PMID 2900496 DOI: 10.1093/Nar/16.14.7209 |
0.437 |
|
| 1988 |
Siddique T, McKinney R, Hung WY, Bartlett RJ, Bruns G, Mohandas TK, Ropers HH, Wilfert C, Roses AD. The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2. Genomics. 3: 156-60. PMID 2852161 DOI: 10.1016/0888-7543(88)90147-4 |
0.48 |
|
| 1987 |
Vance JM, Pericak-Vance MA, Bowman MH, Payne CS, Fredane L, Siddique T, Roses AD, Massey EW. Chorea-acanthocytosis: a report of three new families and implications for genetic counselling. American Journal of Medical Genetics. 28: 403-10. PMID 3322006 DOI: 10.1002/Ajmg.1320280219 |
0.52 |
|
| 1986 |
Roses AD, Pericak-Vance MA, Yamaoka LH, Herbstreith MH, Bartlett RJ, Siddique T, Hung WY, Ross DA, Mohandas TK, Bruns G. A new tightly linked DNA probe for myotonic dystrophy. Neurology. 36: 1146. PMID 3736889 DOI: 10.1212/Wnl.36.8.1146 |
0.417 |
|
| 1985 |
Askanas V, Engel WK, Kwan HH, Reddy NB, Husainy T, Carlo J, Siddique T, Schwartzman RJ, Hanna CJ. Autosomal dominant syndrome of lipid neuromyopathy with normal carnitine: successful treatment with long-chain fatty-acid-free diet. Neurology. 35: 66-72. PMID 3966003 DOI: 10.1212/WNL.35.1.66 |
0.471 |
|
| 1983 |
Engel WK, Siddique T, Nicoloff JT. Effect on weakness and spasticity in amyotrophic lateral sclerosis of thyrotropin-releasing hormone. Lancet. 2: 73-5. PMID 6134961 DOI: 10.1016/S0140-6736(83)90060-0 |
0.55 |
|
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