Gerard Karsenty, Md - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Cellular/Molecular/Developmental Neuroscience

226 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Karsenty G. The facts of the matter: What is a hormone? Plos Genetics. 16: e1008938. PMID 32589668 DOI: 10.1371/Journal.Pgen.1008938  0.36
2020 Chowdhury S, Schulz LC, Palmisano B, Singh P, Berger JM, Yadav VK, Mera P, Ellingsgaard H, Hidalgo J, Brüning JC, Karsenty G. Muscle derived interleukin-6 increases exercise capacity by signaling in osteoblasts. The Journal of Clinical Investigation. PMID 32078586 DOI: 10.1172/Jci133572  0.92
2019 Berger JM, Singh P, Khrimian L, Morgan DA, Chowdhury S, Arteaga-Solis E, Horvath TL, Domingos AI, Marsland AL, Kumal Yadav V, Rahmouni K, Gao XB, Karsenty G. Mediation of the Acute Stress Response by the Skeleton. Cell Metabolism. PMID 31523009 DOI: 10.1016/J.Cmet.2019.08.012  0.72
2019 Jacome-Galarza CE, Percin GI, Muller JT, Mass E, Lazarov T, Eitler J, Rauner M, Yadav VK, Crozet L, Bohm M, Loyher PL, Karsenty G, Waskow C, Geissmann F. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. PMID 30971820 DOI: 10.1038/S41586-019-1105-7  0.92
2019 Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, et al. Publisher Correction: Serotonin signals through a gut-liver axis to regulate hepatic steatosis. Nature Communications. 10: 158. PMID 30622275 DOI: 10.1038/S41467-018-08085-X  0.92
2018 Kim H, Kim YG, Choi W, Moon JH, Hwang I, Kim K, Yadav VK, Karsenty G, Jeong JS, Kim H. Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Scientific Reports. 8: 17642. PMID 30518775 DOI: 10.1038/S41598-018-36097-6  0.92
2018 Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, et al. Serotonin signals through a gut-liver axis to regulate hepatic steatosis. Nature Communications. 9: 4824. PMID 30446669 DOI: 10.1038/S41467-018-07287-7  0.92
2018 Obri A, Khrimian L, Karsenty G, Oury F. Osteocalcin in the brain: from embryonic development to age-related decline in cognition. Nature Reviews. Endocrinology. PMID 29376523 DOI: 10.1038/Nrendo.2017.181  0.8
2018 Ducy PF, Karsenty G. Endocrine Bioenergetics of Bone Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 1012-1019. DOI: 10.1002/9781119266594.Ch130  1
2017 Mera P, Laue K, Wei J, Berger JM, Karsenty G. Corrigendum to "Osteocalcin is necessary and sufficient to maintain muscle mass in older mice" [Mol Metabol 5 (2017) 1042-1047]. Molecular Metabolism. 6: 941. PMID 29277340 DOI: 10.1016/J.Molmet.2017.06.006  0.6
2017 Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G. Gpr158 mediates osteocalcin's regulation of cognition. The Journal of Experimental Medicine. PMID 28851741 DOI: 10.1084/Jem.20171320  0.8
2016 Liu JM, Rosen CJ, Ducy P, Kousteni S, Karsenty G. Regulation of Glucose Handling by the Skeleton: Insights From Mouse and Human Studies. Diabetes. 65: 3225-3232. PMID 27959858 DOI: 10.2337/Db16-0053  1
2016 Mera P, Laue K, Wei J, Berger JM, Karsenty G. Osteocalcin is necessary and sufficient to maintain muscle mass in older mice. Molecular Metabolism. 5: 1042-7. PMID 27689017 DOI: 10.1016/J.Molmet.2016.07.002  0.6
2016 Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, ... Karsenty G, et al. Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. Cell. PMID 27133169 DOI: 10.1016/J.Cell.2016.03.033  0.56
2016 Shimazu J, Wei J, Karsenty G. Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148. Cell Reports. PMID 27052174 DOI: 10.1016/J.Celrep.2016.03.003  1
2016 Karsenty G, Olson EN. Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication. Cell. 164: 1248-56. PMID 26967290 DOI: 10.1016/J.Cell.2016.02.043  0.56
2016 Mera P, Laue K, Wei J, Berger JM, Karsenty G. Osteocalcin is necessary and sufficient to maintain muscle mass in older mice Molecular Metabolism. DOI: 10.1016/j.molmet.2016.07.002  0.56
2015 Wei J, Flaherty S, Karsenty G. Searching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics. Expert Review of Endocrinology & Metabolism. 10: 413-424. PMID 27588033 DOI: 10.1586/17446651.2015.1058152  0.6
2015 Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Lezaki T, Pessin JE, Hinoi E, Karsenty G. Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell. 161: 1576-91. PMID 26091038 DOI: 10.1016/J.Cell.2015.05.029  0.56
2015 Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, et al. Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nature Communications. 6: 6794. PMID 25864946 DOI: 10.1038/Ncomms7794  1
2015 Wei J, Karsenty G. An overview of the metabolic functions of osteocalcin. Current Osteoporosis Reports. 13: 180-5. PMID 25809656 DOI: 10.1007/S11914-015-0267-Y  1
2015 Ferron M, Lacombe J, Germain A, Oury F, Karsenty G. GGCX and VKORC1 inhibit osteocalcin endocrine functions. The Journal of Cell Biology. 208: 761-76. PMID 25753038 DOI: 10.1083/Jcb.201409111  1
2015 Makinistoglu MP, Karsenty G. The class II histone deacetylase HDAC4 regulates cognitive, metabolic and endocrine functions through its expression in osteoblasts. Molecular Metabolism. 4: 64-9. PMID 25685691 DOI: 10.1016/J.Molmet.2014.10.004  1
2015 Swanson CM, Shea SA, Stone KL, Cauley JA, Rosen CJ, Redline S, Karsenty G, Orwoll ES. Obstructive sleep apnea and metabolic bone disease: insights into the relationship between bone and sleep. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 199-211. PMID 25639209 DOI: 10.1002/Jbmr.2446  1
2015 Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, ... ... Karsenty G, et al. Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell. 160: 269-84. PMID 25594183 DOI: 10.1016/J.Cell.2014.11.042  1
2015 Zhang F, Xu L, Xu L, Xu Q, Li D, Yang Y, Karsenty G, Chen CD. JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice. Journal of Molecular Cell Biology. 7: 23-34. PMID 25587042 DOI: 10.1093/Jmcb/Mjv003  1
2015 Karsenty G. Re-tuning bone formation. The Journal of Experimental Medicine. 212: 3. PMID 25582313 DOI: 10.1084/Jem.2121Insight2  1
2015 Wei J, Karsenty G. An overview of the metabolic functions of osteocalcin. Reviews in Endocrine & Metabolic Disorders. 16: 93-8. PMID 25577163 DOI: 10.1007/S11154-014-9307-7  1
2015 Kim K, Oh CM, Ohara-Imaizumi M, Park S, Namkung J, Yadav VK, Tamarina NA, Roe MW, Philipson LH, Karsenty G, Nagamatsu S, German MS, Kim H. Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology. 156: 444-52. PMID 25426873 DOI: 10.1210/En.2014-1687  1
2015 Wei J, Flaherty SE, Karsenty G. Searching for additional endocrine functions of the skeleton: Genetic approaches and implications for therapeutics Expert Review of Endocrinology and Metabolism. 10: 413-424. DOI: 10.1586/17446651.2015.1058152  0.56
2015 Zhang F, Xu L, Xu Q, Karsenty G, Chen CD. Histone demethylase JMJD3 is required for osteoblast differentiation in mice Scientific Reports. 5. DOI: 10.1038/srep13418  0.56
2014 Kode A, Obri A, Paone R, Kousteni S, Ducy P, Karsenty G. Lrp5 regulation of bone mass and serotonin synthesis in the gut. Nature Medicine. 20: 1228-9. PMID 25375916 DOI: 10.1038/Nm.3698  1
2014 Huesa C, Zhu D, Glover JD, Ferron M, Karsenty G, Milne EM, Millan JL, Ahmed SF, Farquharson C, Morton NM, MacRae VE. Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes. Disease Models & Mechanisms. 7: 1341-50. PMID 25368121 DOI: 10.1242/Dmm.017905  1
2014 Kajimura D, Paone R, Mann JJ, Karsenty G. Foxo1 regulates Dbh expression and the activity of the sympathetic nervous system in vivo. Molecular Metabolism. 3: 770-7. PMID 25353004 DOI: 10.1016/J.Molmet.2014.07.006  1
2014 Karsenty G. Broadening the role of osteocalcin in Leydig cells. Endocrinology. 155: 4115-6. PMID 25325424 DOI: 10.1210/En.2014-1703  1
2014 Obri A, Makinistoglu MP, Zhang H, Karsenty G. HDAC4 integrates PTH and sympathetic signaling in osteoblasts. The Journal of Cell Biology. 205: 771-80. PMID 24934156 DOI: 10.1083/Jcb.201403138  1
2014 Bornstein S, Brown SA, Le PT, Wang X, DeMambro V, Horowitz MC, MacDougald O, Baron R, Lotinun S, Karsenty G, Wei W, Ferron M, Kovacs CS, Clemmons D, Wan Y, et al. FGF-21 and skeletal remodeling during and after lactation in C57BL/6J mice. Endocrinology. 155: 3516-26. PMID 24914939 DOI: 10.1210/En.2014-1083  1
2014 Wei J, Ferron M, Clarke CJ, Hannun YA, Jiang H, Blaner WS, Karsenty G. Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation. The Journal of Clinical Investigation. 124: 1-13. PMID 24642469 DOI: 10.1172/Jci72323  1
2014 Riddle RC, Frey JL, Tomlinson RE, Ferron M, Li Y, DiGirolamo DJ, Faugere MC, Hussain MA, Karsenty G, Clemens TL. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. Molecular and Cellular Biology. 34: 1850-62. PMID 24591652 DOI: 10.1128/Mcb.00075-14  1
2014 Karsenty G, Oury F. Regulation of male fertility by the bone-derived hormone osteocalcin. Molecular and Cellular Endocrinology. 382: 521-6. PMID 24145129 DOI: 10.1016/J.Mce.2013.10.008  1
2014 Wei J, Hanna T, Suda N, Karsenty G, Ducy P. Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a. Diabetes. 63: 1021-31. PMID 24009262 DOI: 10.2337/Db13-0887  1
2014 Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Corrigendum: Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis Journal of Clinical Investigation. 124: 5522. DOI: 10.1172/JCI79293  1
2014 Karsenty G. Bone as an Endocrine Organ Cellular Endocrinology in Health and Disease. 193-205. DOI: 10.1016/B978-0-12-408134-5.00012-3  1
2013 Lacombe J, Karsenty G, Ferron M. In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice. Molecular Metabolism. 2: 498-504. PMID 24327965 DOI: 10.1016/J.Molmet.2013.08.004  1
2013 Nohara K, Liu S, Meyers MS, Waget A, Ferron M, Karsenty G, Burcelin R, Mauvais-Jarvis F. Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice. The Journal of Endocrinology. 219: 259-68. PMID 24084835 DOI: 10.1530/Joe-13-0230  1
2013 Oury F, Khrimian L, Denny CA, Gardin A, Chamouni A, Goeden N, Huang YY, Lee H, Srinivas P, Gao XB, Suyama S, Langer T, Mann JJ, Horvath TL, Bonnin A, ... Karsenty G, et al. Maternal and offspring pools of osteocalcin influence brain development and functions. Cell. 155: 228-41. PMID 24074871 DOI: 10.1016/J.Cell.2013.08.042  1
2013 Lacombe J, Karsenty G, Ferron M. Regulation of lysosome biogenesis and functions in osteoclasts. Cell Cycle (Georgetown, Tex.). 12: 2744-52. PMID 23966172 DOI: 10.4161/Cc.25825  1
2013 Gillespie JR, Bush JR, Bell GI, Aubrey LA, Dupuis H, Ferron M, Kream B, DiMattia G, Patel S, Woodgett JR, Karsenty G, Hess DA, Beier F. GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 154: 3702-18. PMID 23904355 DOI: 10.1210/En.2013-1155  1
2013 Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. The Journal of Clinical Investigation. 123: 2421-33. PMID 23728177 DOI: 10.1172/Jci65952  1
2013 Kajimura D, Lee HW, Riley KJ, Arteaga-Solis E, Ferron M, Zhou B, Clarke CJ, Hannun YA, DePinho RA, Guo XE, Guo EX, Mann JJ, Karsenty G. Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metabolism. 17: 901-15. PMID 23684624 DOI: 10.1016/J.Cmet.2013.04.009  1
2013 Nohara K, Waraich RS, Liu S, Ferron M, Waget A, Meyers MS, Karsenty G, Burcelin R, Mauvais-Jarvis F. Developmental androgen excess programs sympathetic tone and adipose tissue dysfunction and predisposes to a cardiometabolic syndrome in female mice. American Journal of Physiology. Endocrinology and Metabolism. 304: E1321-30. PMID 23612996 DOI: 10.1152/Ajpendo.00620.2012  1
2013 Ferron M, Settembre C, Shimazu J, Lacombe J, Kato S, Rawlings DJ, Ballabio A, Karsenty G. A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts. Genes & Development. 27: 955-69. PMID 23599343 DOI: 10.1101/Gad.213827.113  1
2013 Chen J, Magnusson J, Karsenty G, Cummings KJ. Time- and age-dependent effects of serotonin on gasping and autoresuscitation in neonatal mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 114: 1668-76. PMID 23558391 DOI: 10.1152/Japplphysiol.00003.2013  1
2013 Takarada T, Hinoi E, Nakazato R, Ochi H, Xu C, Tsuchikane A, Takeda S, Karsenty G, Abe T, Kiyonari H, Yoneda Y. An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2064-9. PMID 23553905 DOI: 10.1002/Jbmr.1945  1
2013 Zee T, Boller S, Györy I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G. The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. Febs Letters. 587: 711-6. PMID 23395800 DOI: 10.1016/J.Febslet.2013.01.049  1
2013 Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Nakamichi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, ... ... Karsenty G, et al. Vitamin D receptor in osteoblasts is a negative regulator of bone mass control. Endocrinology. 154: 1008-20. PMID 23389957 DOI: 10.1210/En.2012-1542  1
2013 Watanabe T, Oyama T, Asada M, Harada D, Ito Y, Inagawa M, Suzuki Y, Sugano S, Katsube K, Karsenty G, Komori T, Kitagawa M, Asahara H. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development. Plos Genetics. 9: e1003132. PMID 23326237 DOI: 10.1371/Journal.Pgen.1003132  1
2013 Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metabolism. 17: 35-48. PMID 23312282 DOI: 10.1016/J.Cmet.2012.12.004  1
2013 Plotton I, Oury F, Confavreux C, Morel Y, Lejeune H, Karsenty G. Et si l’ostéocalcine était aussi un régulateur de la biosynthèse de la testostérone chez l’homme Annales D Endocrinologie. 74: 265. DOI: 10.1016/J.Ando.2013.07.094  0.8
2013 Karsenty G. Introduction: The Rational of the Work or the Overarching Hypothesis Translational Endocrinology of Bone. 1-3. DOI: 10.1016/B978-0-12-415784-2.00001-4  1
2013 Ferron M, Oury F, Karsenty G. Energy Homeostasis and Neuronal Regulation of Bone Remodeling Genetics of Bone Biology and Skeletal Disease. 69-80. DOI: 10.1016/B978-0-12-387829-8.00005-6  1
2013 Karsenty G. Translational Endocrinology of Bone Translational Endocrinology of Bone 1
2012 Sumara G, Sumara O, Kim JK, Karsenty G. Gut-derived serotonin is a multifunctional determinant to fasting adaptation. Cell Metabolism. 16: 588-600. PMID 23085101 DOI: 10.1016/J.Cmet.2012.09.014  1
2012 Karsenty G. Tribute to L. J. Henderson, a remarkable physiologist, and the founder of the American School of Sociology (1878-1942). American Journal of Physiology. Cell Physiology. 303: C1001-3. PMID 22992676 DOI: 10.1152/Ajpcell.00299.2012  1
2012 Rizzoli R, Cooper C, Reginster JY, Abrahamsen B, Adachi JD, Brandi ML, Bruyère O, Compston J, Ducy P, Ferrari S, Harvey NC, Kanis JA, Karsenty G, Laslop A, Rabenda V, et al. Antidepressant medications and osteoporosis. Bone. 51: 606-13. PMID 22659406 DOI: 10.1016/J.Bone.2012.05.018  1
2012 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G. miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology. 197: 509-21. PMID 22564414 DOI: 10.1083/Jcb.201201057  1
2012 Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, ... Karsenty G, et al. Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 7433-8. PMID 22538810 DOI: 10.1073/Pnas.1109036109  1
2012 Karsenty G. The mutual dependence between bone and gonads. The Journal of Endocrinology. 213: 107-14. PMID 22407998 DOI: 10.1530/Joe-11-0452  1
2012 Arteaga-Solis E, Settembre C, Ballabio A, Karsenty G. Sulfatases are determinants of alveolar formation. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 253-60. PMID 22366163 DOI: 10.1016/J.Matbio.2012.02.001  1
2012 Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, Facchinetti V, Sabatini DM, Ballabio A. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. The Embo Journal. 31: 1095-108. PMID 22343943 DOI: 10.1038/Emboj.2012.32  1
2012 Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR. Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5). The Journal of Biological Chemistry. 287: 12016-26. PMID 22337886 DOI: 10.1074/Jbc.M111.337048  1
2012 Karsenty G, Ferron M. The contribution of bone to whole-organism physiology. Nature. 481: 314-20. PMID 22258610 DOI: 10.1038/Nature10763  1
2012 Zee T, Settembre C, Levine RL, Karsenty G. T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts. Molecular and Cellular Biology. 32: 1080-8. PMID 22252315 DOI: 10.1128/Mcb.06279-11  1
2012 Karsenty G, Oury F. Biology without walls: the novel endocrinology of bone. Annual Review of Physiology. 74: 87-105. PMID 22077214 DOI: 10.1146/Annurev-Physiol-020911-153233  1
2012 Rosen C, Karsenty G, MacDougald O. Foreword: interactions between bone and adipose tissue and metabolism. Bone. 50: 429. PMID 22015817 DOI: 10.1016/J.Bone.2011.10.006  1
2012 Confavreux CB, Borel O, Lee F, Vaz G, Guyard M, Fadat C, Carlier MC, Chapurlat R, Karsenty G. Osteoid osteoma is an osteocalcinoma affecting glucose metabolism. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 23: 1645-50. PMID 21681611 DOI: 10.1007/S00198-011-1684-0  1
2012 Ferron M, McKee MD, Levine RL, Ducy P, Karsenty G. Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice. Bone. 50: 568-75. PMID 21550430 DOI: 10.1016/J.Bone.2011.04.017  1
2012 Karsenty G. Update osteocalcin biology Bone. 51: S12-S13. DOI: 10.1016/J.Bone.2012.08.037  0.52
2011 Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, ... Karsenty G, et al. Sympathetic control of bone mass regulated by osteopontin. Proceedings of the National Academy of Sciences of the United States of America. 108: 17767-72. PMID 21990347 DOI: 10.1073/Pnas.1109402108  1
2011 Karsenty G. Bone endocrine regulation of energy metabolism and male reproduction. Comptes Rendus Biologies. 334: 720-4. PMID 21943521 DOI: 10.1016/J.Crvi.2011.07.007  1
2011 Karsenty G. Regulation of male fertility by bone Cold Spring Harbor Symposia On Quantitative Biology. 76: 279-283. PMID 21859673 DOI: 10.1101/sqb.2011.76.010934  1
2011 Karsenty G, Gershon MD. The importance of the gastrointestinal tract in the control of bone mass accrual. Gastroenterology. 141: 439-42. PMID 21699800 DOI: 10.1053/J.Gastro.2011.06.011  1
2011 Inose H, Zhou B, Yadav VK, Guo XE, Karsenty G, Ducy P. Efficacy of serotonin inhibition in mouse models of bone loss. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2002-11. PMID 21608033 DOI: 10.1002/Jbmr.439  1
2011 Oury F, Karsenty G. Towards a serotonin-dependent leptin roadmap in the brain. Trends in Endocrinology and Metabolism: Tem. 22: 382-7. PMID 21602053 DOI: 10.1016/J.Tem.2011.04.006  1
2011 Kajimura D, Hinoi E, Ferron M, Kode A, Riley KJ, Zhou B, Guo XE, Karsenty G. Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual. The Journal of Experimental Medicine. 208: 841-51. PMID 21444660 DOI: 10.1084/Jem.20102608  1
2011 Clemens TL, Karsenty G. The osteoblast: an insulin target cell controlling glucose homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 677-80. PMID 21433069 DOI: 10.1002/Jbmr.321  1
2011 Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G. Endocrine regulation of male fertility by the skeleton. Cell. 144: 796-809. PMID 21333348 DOI: 10.1016/J.Cell.2011.02.004  1
2011 Yadav VK, Oury F, Tanaka KF, Tanaka K, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. The Journal of Experimental Medicine. 208: 41-52. PMID 21187319 DOI: 10.1084/Jem.20101940  0.92
2011 Karsenty G, Yadav VK. Regulation of bone mass by serotonin: molecular biology and therapeutic implications. Annual Review of Medicine. 62: 323-31. PMID 21073335 DOI: 10.1146/Annurev-Med-090710-133426  1
2011 Yadav VK, Oury F, Tanaka KF, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: Temporal specificity, transcriptional regulation, and therapeutic implications (The Journal of Experimental Medicine (2011) 208, 1, (41-52)) Journal of Experimental Medicine. 208: 413. DOI: 10.1084/Jem.201019402082C  1
2011 Karsenty G. What makes an osteoclast special? Developmental Cell. 20: e2. DOI: 10.1016/J.Devcel.2011.05.005  1
2010 Karsenty G, Oury F. The central regulation of bone mass, the first link between bone remodeling and energy metabolism. The Journal of Clinical Endocrinology and Metabolism. 95: 4795-801. PMID 21051575 DOI: 10.1210/Jc.2010-1030  1
2010 Oury F, Yadav VK, Wang Y, Zhou B, Liu XS, Guo XE, Tecott LH, Schutz G, Means AR, Karsenty G. CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons. Genes & Development. 24: 2330-42. PMID 20952540 DOI: 10.1101/Gad.1977210  1
2010 Ducy P, Karsenty G. The two faces of serotonin in bone biology. The Journal of Cell Biology. 191: 7-13. PMID 20921133 DOI: 10.1083/Jcb.201006123  1
2010 Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Carta L, Ono RN, Sengle G, Arteaga-Solis E, Levasseur R, Ducy P, Sakai LY, Karsenty G, Ramirez F. Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation. The Journal of Cell Biology. 190: 1107-21. PMID 20855508 DOI: 10.1083/Jcb.201003089  1
2010 Oury F, Karsenty G. [Serotonin, two faces of a unique molecule in the regulation of bone mass]. MéDecine Sciences : M/S. 26: 713-8. PMID 20819707 DOI: 10.1051/Medsci/2010268-9713  1
2010 Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G. Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell. 142: 296-308. PMID 20655470 DOI: 10.1016/J.Cell.2010.06.003  1
2010 Ferron M, Wei J, Yoshizawa T, Ducy P, Karsenty G. An ELISA-based method to quantify osteocalcin carboxylation in mice. Biochemical and Biophysical Research Communications. 397: 691-6. PMID 20570657 DOI: 10.1016/J.Bbrc.2010.06.008  1
2010 Frost M, Andersen TE, Yadav V, Brixen K, Karsenty G, Kassem M. Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 673-5. PMID 20200960 DOI: 10.1002/Jbmr.44  1
2010 Shi Y, Oury F, Yadav VK, Wess J, Liu XS, Guo XE, Murshed M, Karsenty G. Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity. Cell Metabolism. 11: 231-8. PMID 20197056 DOI: 10.1016/J.Cmet.2010.01.005  1
2010 Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R, Vidal M, Karsenty G, Ducy P. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nature Medicine. 16: 308-12. PMID 20139991 DOI: 10.1038/Nm.2098  1
2010 Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice. The Journal of Clinical Investigation. 120: 357-68. PMID 20038793 DOI: 10.1172/Jci39901  1
2010 Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS. Parathyroid hormone regulates fetal-placental mineral homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 594-605. PMID 19968565 DOI: 10.1359/Jbmr.090825  1
2010 Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice (Journal of Clinical Investigation (2010) 120, 1 (357-368) (DOI:10.1172/JCI39901)) Journal of Clinical Investigation. 120: 932. DOI: 10.1172/Jci37672E1  1
2010 Karsenty G. Preface to skeletal biology and medicine Annals of the New York Academy of Sciences. 1192: xi. DOI: 10.1111/J.1749-6632.2009.05311.X  1
2009 Yadav VK, Karsenty G. Leptin-dependent co-regulation of bone and energy metabolism. Aging. 1: 954-6. PMID 20157577  1
2009 Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG, Chua SC, Wang Q, Kim JK, Kaestner KH, Karsenty G. An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion. Annals of the New York Academy of Sciences. 1173: E20-30. PMID 19751411 DOI: 10.1111/J.1749-6632.2009.05061.X  1
2009 Karsenty G. Integrative physiology. Preface. Annals of the New York Academy of Sciences. 1173: E1. PMID 19751408 DOI: 10.1111/J.1749-6632.2009.05065.X  1
2009 Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 138: 976-89. PMID 19737523 DOI: 10.1016/J.Cell.2009.06.051  0.92
2009 Yoshizawa T, Hinoi E, Jung DY, Kajimura D, Ferron M, Seo J, Graff JM, Kim JK, Karsenty G. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. The Journal of Clinical Investigation. 119: 2807-17. PMID 19726872 DOI: 10.1172/Jci39366  1
2009 Ferron M, Karsenty G. The gutsy side of bone. Cell Metabolism. 10: 7-8. PMID 19583948 DOI: 10.1016/J.Cmet.2009.06.004  1
2009 Karsenty G, Kronenberg HM, Settembre C. Genetic control of bone formation. Annual Review of Cell and Developmental Biology. 25: 629-48. PMID 19575648 DOI: 10.1146/Annurev.Cellbio.042308.113308  1
2009 Oury F, Karsenty G. [Intestinal serotonin and regulation of bone mass]. MéDecine Sciences : M/S. 25: 445-6. PMID 19480820 DOI: 10.1051/Medsci/2009255445  1
2009 Confavreux CB, Levine RL, Karsenty G. A paradigm of integrative physiology, the crosstalk between bone and energy metabolisms. Molecular and Cellular Endocrinology. 310: 21-9. PMID 19376193 DOI: 10.1016/J.Mce.2009.04.004  1
2009 Kang S, Elf S, Dong S, Hitosugi T, Lythgoe K, Guo A, Ruan H, Lonial S, Khoury HJ, Williams IR, Lee BH, Roesel JL, Karsenty G, Hanauer A, Taunton J, et al. Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation. Molecular and Cellular Biology. 29: 2105-17. PMID 19223461 DOI: 10.1128/Mcb.00998-08  1
2009 Settembre C, Arteaga-Solis E, Ballabio A, Karsenty G. Self-eating in skeletal development: implications for lysosomal storage disorders. Autophagy. 5: 228-9. PMID 19029806 DOI: 10.4161/Auto.5.2.7390  1
2009 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, John Mann J, Hen R, Ducy P, Karsenty G. LDL-receptor related protein five controls bone formation by inhibiting serotonin synthesis in the duodenum Obstetrical and Gynecological Survey. 64: 240-242. DOI: 10.1097/01.Ogx.0000345723.85624.24  1
2009 Karsenty G. Cell Differentiation in the Skeleton Essentials of Stem Cell Biology. 223-226. DOI: 10.1016/B978-0-12-374729-7.00026-3  1
2009 Karsenty G, Elefteriou F. Neuronal Regulation of Bone Remodeling Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition. 56-60. DOI: 10.1002/9780470623992.Ch10  1
2008 Shi Y, Yadav VK, Suda N, Liu XS, Guo XE, Myers MG, Karsenty G. Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 20529-33. PMID 19074282 DOI: 10.1073/Pnas.0808701106  0.92
2008 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell. 135: 825-37. PMID 19041748 DOI: 10.1016/J.Cell.2008.09.059  1
2008 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G. Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes & Development. 22: 2645-50. PMID 18832069 DOI: 10.1101/Gad.1711308  1
2008 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, et al. The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease. Arthritis and Rheumatism. 58: 2764-75. PMID 18759297 DOI: 10.1002/Art.23805  1
2008 Singh MK, Elefteriou F, Karsenty G. Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule. Endocrinology. 149: 3933-41. PMID 18450969 DOI: 10.1210/En.2008-0109  0.92
2008 Lee NK, Karsenty G. Reciprocal regulation of bone and energy metabolism. Trends in Endocrinology and Metabolism: Tem. 19: 161-6. PMID 18407515 DOI: 10.1016/J.Tem.2008.02.006  1
2008 Ferron M, Hinoi E, Karsenty G, Ducy P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5266-70. PMID 18362359 DOI: 10.1073/Pnas.0711119105  1
2007 Galler KM, Yasue A, Cavender AC, Bialek P, Karsenty G, D'Souza RN. A novel role for Twist-1 in pulp homeostasis. Journal of Dental Research. 86: 951-5. PMID 17890670 DOI: 10.1177/154405910708601007  1
2007 Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G. Endocrine regulation of energy metabolism by the skeleton. Cell. 130: 456-69. PMID 17693256 DOI: 10.1016/J.Cell.2007.05.047  1
2007 Glass DA, Karsenty G. In vivo analysis of Wnt signaling in bone. Endocrinology. 148: 2630-4. PMID 17395705 DOI: 10.1210/En.2006-1372  1
2007 Kaartinen MT, Murshed M, Karsenty G, McKee MD. Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 375-86. PMID 17189522 DOI: 10.1369/Jhc.6A7087.2006  0.8
2007 Karsenty G. Update on the transcriptional control of osteoblast differentiation Bonekey-Osteovision. 4: 164-170. DOI: 10.1138/20070262  0.48
2007 Karsenty G. Genetic study of children's bone health and its therapeutic application Bone. 40: S14. DOI: 10.1016/J.Bone.2007.04.149  0.52
2006 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metabolism. 4: 441-51. PMID 17141628 DOI: 10.1016/J.Cmet.2006.10.010  1
2006 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G. Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes & Development. 20: 2937-42. PMID 17050674 DOI: 10.1101/Gad.1482906  1
2006 Glass DA, Karsenty G. Canonical Wnt signaling in osteoblasts is required for osteoclast differentiation. Annals of the New York Academy of Sciences. 1068: 117-30. PMID 16831912 DOI: 10.1196/Annals.1346.015  1
2006 Glass DA, Karsenty G. Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway. Current Topics in Developmental Biology. 73: 43-84. PMID 16782455 DOI: 10.1016/S0070-2153(05)73002-7  1
2006 Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Fariñas I, Karsenty G, Grosschedl R. SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 125: 971-86. PMID 16751105 DOI: 10.1016/J.Cell.2006.05.012  1
2006 Winslow MM, Pan M, Starbuck M, Gallo EM, Deng L, Karsenty G, Crabtree GR. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Developmental Cell. 10: 771-82. PMID 16740479 DOI: 10.1016/J.Devcel.2006.04.006  1
2006 Ahn JD, Dubern B, Lubrano-Berthelier C, Clement K, Karsenty G. Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency. Endocrinology. 147: 3196-202. PMID 16614075 DOI: 10.1210/En.2006-0281  0.4
2006 Zaheer A, Murshed M, De Grand AM, Morgan TG, Karsenty G, Frangioni JV. Optical imaging of hydroxyapatite in the calcified vasculature of transgenic animals. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1132-6. PMID 16484598 DOI: 10.1161/01.Atv.0000210016.89991.2A  1
2006 Guo J, Chung UI, Yang D, Karsenty G, Bringhurst FR, Kronenberg HM. PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Developmental Biology. 292: 116-28. PMID 16476422 DOI: 10.1016/J.Ydbio.2005.12.044  0.56
2006 Wang X, Kua HY, Hu Y, Guo K, Zeng Q, Wu Q, Ng HH, Karsenty G, de Crombrugghe B, Yeh J, Li B. p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. The Journal of Cell Biology. 172: 115-25. PMID 16380437 DOI: 10.1083/Jcb.200507106  0.68
2005 Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 437: 417-21. PMID 16163358 DOI: 10.1038/Nature03928  1
2005 Fu L, Patel MS, Bradley A, Wagner EF, Karsenty G. The molecular clock mediates leptin-regulated bone formation. Cell. 122: 803-15. PMID 16143109 DOI: 10.1016/J.Cell.2005.06.028  1
2005 Li L, Zhu J, Tu Q, Yamauchi M, Sodek J, Karsenty G, Tang J, Chen J. An in vivo model to study osteogenic gene regulation: targeting an avian retroviral receptor (TVA) to bone with the bone sialoprotein (BSP) promoter. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1403-13. PMID 16007338 DOI: 10.1359/Jbmr.050316  0.36
2005 Xiao G, Jiang D, Ge C, Zhao Z, Lai Y, Boules H, Phimphilai M, Yang X, Karsenty G, Franceschi RT. Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. The Journal of Biological Chemistry. 280: 30689-96. PMID 16000305 DOI: 10.1074/Jbc.M500750200  1
2005 Dabovic B, Levasseur R, Zambuto L, Chen Y, Karsenty G, Rifkin DB. Osteopetrosis-like phenotype in latent TGF-β binding protein 3 deficient mice Bone. 37: 25-31. PMID 15878314 DOI: 10.1016/J.Bone.2005.02.021  1
2005 Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Developmental Cell. 8: 751-64. PMID 15866165 DOI: 10.1016/J.Devcel.2005.02.017  1
2005 Murshed M, Harmey D, Millán JL, McKee MD, Karsenty G. Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes & Development. 19: 1093-104. PMID 15833911 DOI: 10.1101/Gad.1276205  0.8
2005 Sakamoto A, Chen M, Nakamura T, Xie T, Karsenty G, Weinstein LS. Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone. The Journal of Biological Chemistry. 280: 21369-75. PMID 15797856 DOI: 10.1074/Jbc.M500346200  0.4
2005 Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 434: 514-20. PMID 15724149 DOI: 10.1038/Nature03398  1
2005 Karsenty G. New examples of a central control of bone mass Bonekey-Osteovision. 2: 34-35. DOI: 10.1138/20050185  0.36
2004 Chen YT, Levasseur R, Vaishnav S, Karsenty G, Bradley A. Bigenic Cre/loxP, puDeltatk conditional genetic ablation. Nucleic Acids Research. 32: e161. PMID 15561996 DOI: 10.1093/Nar/Gnh158  0.56
2004 Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell. 119: 555-66. PMID 15537544 DOI: 10.1016/J.Cell.2004.10.024  1
2004 Yang X, Karsenty G. ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. The Journal of Biological Chemistry. 279: 47109-14. PMID 15377660 DOI: 10.1074/Jbc.M410010200  1
2004 Cock TA, Back J, Elefteriou F, Karsenty G, Kastner P, Chan S, Auwerx J. Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen. Embo Reports. 5: 1007-12. PMID 15359271 DOI: 10.1038/Sj.Embor.7400254  0.92
2004 Gordon CM, Bachrach LK, Carpenter TO, Karsenty G, Rauch F. Bone health in children and adolescents: A Symposium at the Annual Meeting of the Pediatric Academic Societies/Lawson Wilkins Pediatric Endocrine Society, May 2003 Current Problems in Pediatric and Adolescent Health Care. 34: 226-242. PMID 15232554 DOI: 10.1016/J.Cppeds.2004.03.001  1
2004 Murshed M, Schinke T, McKee MD, Karsenty G. Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins. The Journal of Cell Biology. 165: 625-30. PMID 15184399 DOI: 10.1083/Jcb.200402046  1
2004 Wang W, Wang YG, Reginato AM, Glotzer DJ, Fukai N, Plotkina S, Karsenty G, Olsen BR. Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice. Developmental Biology. 270: 364-81. PMID 15183720 DOI: 10.1016/J.Ydbio.2004.03.003  1
2004 Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 117: 387-98. PMID 15109498 DOI: 10.1016/S0092-8674(04)00344-7  1
2004 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A. Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 229: 826-34. PMID 15042706 DOI: 10.1002/Dvdy.20003  1
2004 Bialek P, Kern B, Yang X, Schrock M, Sosic D, Hong N, Wu H, Yu K, Ornitz DM, Olson EN, Justice MJ, Karsenty G. A twist code determines the onset of osteoblast differentiation. Developmental Cell. 6: 423-35. PMID 15030764 DOI: 10.1016/S1534-5807(04)00058-9  1
2004 Dacquin R, Davey RA, Laplace C, Levasseur R, Morris HA, Goldring SR, Gebre-Medhin S, Galson DL, Zajac JD, Karsenty G. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. The Journal of Cell Biology. 164: 509-14. PMID 14970190 DOI: 10.1083/Jcb.200312135  1
2004 Cui Y, Huang L, Elefteriou F, Yang G, Shelton JM, Giles JE, Oz OK, Pourbahrami T, Lu CY, Richardson JA, Karsenty G, Li C. Essential role of STAT3 in body weight and glucose homeostasis. Molecular and Cellular Biology. 24: 258-69. PMID 14673160 DOI: 10.1128/Mcb.24.1.258-269.2004  0.92
2003 Glass DA, Patel MS, Karsenty G. A new insight into the formation of osteolytic lesions in multiple myeloma. The New England Journal of Medicine. 349: 2479-80. PMID 14695406 DOI: 10.1056/Nejmp038176  1
2003 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R. Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. The Journal of Cell Biology. 162: 139-48. PMID 12835312 DOI: 10.1083/Jcb.200302066  1
2003 Levasseur R, Barrios R, Elefteriou F, Glass DA, Lieberman MW, Karsenty G. Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice. Endocrinology. 144: 2761-4. PMID 12810527 DOI: 10.1210/En.2002-0071  1
2003 Tu Q, Pi M, Karsenty G, Simpson L, Liu S, Quarles LD. Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background. The Journal of Clinical Investigation. 111: 1029-37. PMID 12671052 DOI: 10.1172/Jci200317054  0.36
2003 Cui CB, Cooper LF, Yang X, Karsenty G, Aukhil I. Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ. Molecular and Cellular Biology. 23: 1004-13. PMID 12529404 DOI: 10.1128/Mcb.23.3.1004-1013.2003  1
2002 Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell. 111: 305-17. PMID 12419242 DOI: 10.1016/S0092-8674(02)01049-8  1
2002 Byers BA, Pavlath GK, Murphy TJ, Karsenty G, García AJ. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1931-44. PMID 12412799 DOI: 10.1359/Jbmr.2002.17.11.1931  1
2002 Speer MY, McKee MD, Guldberg RE, Liaw L, Yang HY, Tung E, Karsenty G, Giachelli CM. Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo. The Journal of Experimental Medicine. 196: 1047-55. PMID 12391016 DOI: 10.1084/Jem.20020911  1
2002 Yang X, Karsenty G. Transcription factors in bone: developmental and pathological aspects. Trends in Molecular Medicine. 8: 340-5. PMID 12114114 DOI: 10.1016/S1471-4914(02)02340-7  1
2002 Dacquin R, Starbuck M, Schinke T, Karsenty G. Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 224: 245-51. PMID 12112477 DOI: 10.1002/Dvdy.10100  1
2002 Kobayashi T, Chung UI, Schipani E, Starbuck M, Karsenty G, Katagiri T, Goad DL, Lanske B, Kronenberg HM. PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development (Cambridge, England). 129: 2977-86. PMID 12050144  0.72
2002 Kato M, Patel MS, Levasseur R, Lobov I, Chang BH, Glass DA, Hartmann C, Li L, Hwang TH, Brayton CF, Lang RA, Karsenty G, Chan L. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. The Journal of Cell Biology. 157: 303-14. PMID 11956231 DOI: 10.1083/Jcb.200201089  1
2002 O’Brien CA, Kern B, Gubrij I, Karsenty G, Manolagas SC. Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells. Bone. 30: 453-462. PMID 11882458 DOI: 10.1016/S8756-3282(01)00692-5  0.36
2001 Amling M, Pogoda P, Beil FT, Schilling AF, Holzmann T, Priemel M, Blicharski D, Català-Lehnen P, Rueger JM, Ducy P, Karsenty G. Central control of bone mass: brainstorming of the skeleton. Advances in Experimental Medicine and Biology. 496: 85-94. PMID 11783628 DOI: 10.1007/978-1-4615-0651-5_9  1
2001 Steitz SA, Speer MY, Curinga G, Yang HY, Haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM. Smooth muscle cell phenotypic transition associated with calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers Circulation Research. 89: 1147-1154. PMID 11739279 DOI: 10.1161/Hh2401.101070  1
2001 Takeda S, Karsenty G. Central control of bone formation. Journal of Bone and Mineral Metabolism. 19: 195-8. PMID 11368306 DOI: 10.1007/S007740170042  0.44
2001 Karsenty G. The not-so-odd couple--the clinician and the experimentalist. The Journal of Clinical Endocrinology and Metabolism. 86: 1882-3. PMID 11344176 DOI: 10.1210/Jcem.86.5.7561  0.36
2001 Alliston T, Choy L, Ducy P, Karsenty G, Derynck R. TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. The Embo Journal. 20: 2254-72. PMID 11331591 DOI: 10.1093/Emboj/20.9.2254  1
2001 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes & Development. 15: 467-81. PMID 11230154 DOI: 10.1101/Gad.845101  0.68
2001 Kern B, Shen J, Starbuck M, Karsenty G. Cbfa1 Contributes to the Osteoblast-specific Expression of type I collagen Genes Journal of Biological Chemistry. 276: 7101-7107. PMID 11106645 DOI: 10.1074/Jbc.M006215200  0.72
2001 Karsenty G. The central regulation of bone remodeling. Trends in Endocrinology and Metabolism: Tem. 11: 437-9. PMID 11091123 DOI: 10.1016/S1043-2760(00)00322-2  0.52
2001 Amling M, Takeda S, Karsenty G. A neuro (endo)crine regulation of bone remodeling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 970-5. PMID 11056473 DOI: 10.1002/1521-1878(200011)22:11<970::Aid-Bies3>3.0.Co;2-L  0.68
2001 Karsenty G. Contrôle central de la formation osseuse MéDecine/Sciences. 17: 1270-1275. DOI: 10.1051/Medsci/200117121270  0.32
2000 Schinke T, Karsenty G. Vascular calcification—a passive process in need of inhibitors Nephrology Dialysis Transplantation. 15: 1272-1274. PMID 10978374 DOI: 10.1093/Ndt/15.9.1272  1
2000 Ducy P, Schinke T, Karsenty G. The Osteoblast: A Sophisticated Fibroblast under Central Surveillance Science. 289: 1501-1504. PMID 10968779 DOI: 10.1126/Science.289.5484.1501  1
2000 Günther T, Chen ZF, Kim J, Priemel M, Rueger JM, Amling M, Moseley JM, Martin TJ, Anderson DJ, Karsenty G. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature. 406: 199-203. PMID 10910362 DOI: 10.1038/35018111  1
2000 Ducy P, Karsenty G. The family of bone morphogenetic proteins Kidney International. 57: 2207-2214. PMID 10844590 DOI: 10.1046/J.1523-1755.2000.00081.X  1
2000 Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell. 100: 197-207. PMID 10660043 DOI: 10.1016/S0092-8674(00)81558-5  1
2000 McLarren KW, Lo R, Grbavec D, Thirunavukkarasu K, Karsenty G, Stifani S. The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1. The Journal of Biological Chemistry. 275: 530-8. PMID 10617648 DOI: 10.1074/Jbc.275.1.530  1
1999 Zhou G, Chen Y, Zhou L, Thirunavukkarasu K, Hecht J, Chitayat D, Gelb BD, Pirinen S, Berry SA, Greenberg CR, Karsenty G, Lee B. CBFA1 mutation analysis and functional correlation with phenotypic variability in cleidocranial dysplasia. Human Molecular Genetics. 8: 2311-6. PMID 10545612 DOI: 10.1093/Hmg/8.12.2311  0.36
1999 Schinke T, Karsenty G. Characterization of Osf1, an Osteoblast-specific Transcription Factor Binding to a Critical cis-acting Element in the MouseOsteocalcin Promoters Journal of Biological Chemistry. 274: 30182-30189. PMID 10514508 DOI: 10.1074/Jbc.274.42.30182  1
1999 Karsenty G, Ducy P, Starbuck M, Priemel M, Shen J, Geoffroy V, Amling M. Cbfa1 as a regulator of osteoblast differentiation and function. Bone. 25: 107-108. PMID 10423032 DOI: 10.1016/S8756-3282(99)00111-8  1
1999 Ducy P, Starbuck M, Priemel M, Shen J, Pinero G, Geoffroy V, Amling M, Karsenty G. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. Genes & Development. 13: 1025-36. PMID 10215629 DOI: 10.1101/Gad.13.8.1025  0.6
1999 Schinke T, McKee MD, Karsenty G. Extracellular matrix calcification: where is the action? Nature Genetics. 21: 150-1. PMID 9988260 DOI: 10.1038/5928  0.36
1999 Ducy P, Karsenty G. Transcriptional Control of Osteoblast Differentiation The Endocrinologist. 9: 32-35. DOI: 10.1097/00019616-199901000-00007  0.36
1998 Ducy P, Karsenty G. Genetic control of cell differentiation in the skeleton. Current Opinion in Cell Biology. 10: 614-619. PMID 9818172 DOI: 10.1016/S0955-0674(98)80037-9  1
1998 Corral DA, Amling M, Priemel M, Loyer E, Fuchs S, Ducy P, Baron R, Karsenty G. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 13835-40. PMID 9811887 DOI: 10.1073/Pnas.95.23.13835  0.72
1998 Frendo JL, Xiao G, Fuchs S, Franceschi RT, Karsenty G, Ducy P. Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo. The Journal of Biological Chemistry. 273: 30509-16. PMID 9804819 DOI: 10.1074/Jbc.273.46.30509  0.4
1998 Boskey AL, Gadaleta S, Gundberg C, Doty SB, Ducy P, Karsenty G. Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Bone. 23: 187-96. PMID 9737340 DOI: 10.1016/S8756-3282(98)00092-1  1
1998 Thirunavukkarasu K, Mahajan M, McLarren KW, Stifani S, Karsenty G. Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta. Molecular and Cellular Biology. 18: 4197-208. PMID 9632804 DOI: 10.1128/Mcb.18.7.4197  1
1998 Geoffroy V, Corral DA, Zhou L, Lee B, Karsenty G. Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function Mammalian Genome. 9: 54-57. PMID 9434946 DOI: 10.1007/S003359900679  0.72
1998 Schinke T, McKee MD, Kiviranta R, Karsenty G. Trends in Molecular Medicine: Molecular determinants of arterial calcification Annals of Medicine. 30: 538-541. DOI: 10.3109/07853899709002601  1
1997 Lee B, Thirunavukkarasu K, Zhou L, Pastore L, Baldini A, Hecht J, Geoffroy V, Ducy P, Karsenty G. Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nature Genetics. 16: 307-10. PMID 9207800 DOI: 10.1038/Ng0797-307  0.52
1997 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89: 747-54. PMID 9182762 DOI: 10.1016/S0092-8674(00)80257-3  0.4
1997 Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 386: 78-81. PMID 9052783 DOI: 10.1038/386078A0  0.36
1997 Zhang R, Ducy P, Karsenty G. 1,25-Dihydroxyvitamin D3 Inhibits Osteocalcin Expression in Mouse through an Indirect Mechanism Journal of Biological Chemistry. 272: 110-116. PMID 8995235 DOI: 10.1074/Jbc.272.1.110  1
1996 Ducy P, Geoffroy V, Karsenty G. Study of Osteoblast-Specific Expression of One Mouse Osteocalcin Gene: Characterization of the Factor Binding to OSE2 Connective Tissue Research. 35: 7-14. PMID 9084638 DOI: 10.3109/03008209609029169  1
1996 Bronckers AL, Goei W, Luo G, Karsenty G, D'Souza RN, Lyaruu DM, Burger EH. DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end labeling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 1281-91. PMID 8864903 DOI: 10.1002/Jbmr.5650110913  0.52
1996 Bronckers AL, Lyaruu DM, Goei W, Litz M, Luo G, Karsenty G, Wöltgens JH, D'Souza RN. Nuclear DNA fragmentation during postnatal tooth development of mouse and hamster and during dentin repair in the rat. European Journal of Oral Sciences. 104: 102-11. PMID 8804897 DOI: 10.1111/J.1600-0722.1996.Tb00053.X  0.64
1996 Galéra P, Park R, Ducy P, Mattéi M, Karsenty G. c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis. Journal of Biological Chemistry. 271: 21331-21339. PMID 8702912 DOI: 10.1074/Jbc.271.35.21331  1
1996 Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G. Increased bone formation in osteocalcin-deficient mice. Nature. 382: 448-52. PMID 8684484 DOI: 10.1038/382448A0  1
1995 Geoffroy V, Ducy P, Karsenty G. A PEBP2/AML-1-related Factor Increases Osteocalcin Promoter Activity through Its Binding to an Osteoblast-specific cis-Acting Element Journal of Biological Chemistry. 270: 30973-30979. PMID 8537354 DOI: 10.1074/Jbc.270.52.30973  1
1995 Ducy P, Karsenty G. Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene. Molecular and Cellular Biology. 15: 1858-1869. PMID 7891679 DOI: 10.1128/Mcb.15.4.1858  1
1995 Luo G, D'Souza R, Hogue D, Karsenty G. The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development Journal of Bone and Mineral Research. 10: 325-334. PMID 7754814 DOI: 10.1002/Jbmr.5650100221  1
1995 Luo G, Hofmann C, Bronckers AL, Sohocki M, Bradley A, Karsenty G. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes & Development. 9: 2808-20. PMID 7590255 DOI: 10.1101/Gad.9.22.2808  0.44
1994 Galéra P, Musso M, Ducy P, Karsenty G. c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin. Proceedings of the National Academy of Sciences of the United States of America. 91: 9372-9376. PMID 7937772 DOI: 10.1073/Pnas.91.20.9372  1
1993 Mattei MG, Bruce B, Karsenty G. Mouse α1 Type V Collagen Gene Maps to the [A2-B] Region of Chromosome 2 Genomics. 16: 786-788. PMID 8325657 DOI: 10.1006/Geno.1993.1270  1
1991 Karsenty G, de Crombrugghe B. Conservation of binding sites for regulatory factors in the coordinately expressed alpha 1 (I) and alpha 2 (I) collagen promoters. Biochemical and Biophysical Research Communications. 177: 538-44. PMID 2043139 DOI: 10.1016/0006-291X(91)92017-E  0.92
1991 Crombrugghe Bd, Vuorio T, Karsenty G, Maity S, Rutheshouser EC, Goldberg H. Transcriptional control mechanisms for the expression of type I collagen genes. Annals of the Rheumatic Diseases. 50: 872-876. PMID 1750800 DOI: 10.1136/Ard.50.Suppl_4.872  0.4
1990 De Crombrugghe B, Karsenty G, Maity S, Vuorio T, Rossi P, Ruteshouser EC, McKinney SH, Lozano G. Transcriptional mechanisms controlling types I and III collagen genes. Annals of the New York Academy of Sciences. 580: 88-96. PMID 2337308 DOI: 10.1111/J.1749-6632.1990.Tb17921.X  0.4
1988 Maity SN, Golumbek PT, Karsenty G, de Crombrugghe B. Selective activation of transcription by a novel CCAAT binding factor. Science (New York, N.Y.). 241: 582-5. PMID 3399893 DOI: 10.1126/Science.3399893  0.48
1988 Rossi P, Karsenty G, Roberts AB, Roche NS, Sporn MB, de Crombrugghe B. A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta. Cell. 52: 405-14. PMID 2830985 DOI: 10.1016/S0092-8674(88)80033-3  0.36
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