Oscar Alzate - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Alzheimer's disease, Neuroproteomics

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hiller S, DeKroon R, Hamlett ED, Xu L, Osorio C, Robinette J, Winnik W, Simington S, Maeda N, Alzate O, Yi X. Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress. Biochimica Et Biophysica Acta. PMID 26344063 DOI: 10.1016/j.bbagen.2015.09.001  0.8
2015 Jamiolkowski RM, Kang SD, Rodriguez AK, Haseltine JM, Galinat LJ, Jantzen AE, Carlon TA, Darrabie MD, Arciniegas AJ, Mantilla JG, Haley NR, Noviani M, Allen JD, Stabler TV, Frederiksen JW, ... Alzate O, et al. Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. Regenerative Medicine. 10: 447-60. PMID 26022764 DOI: 10.2217/rme.15.2  0.8
2015 Kodavanti PR, Royland JE, Osorio C, Winnik WM, Ortiz P, Lei L, Ramabhadran R, Alzate O. Developmental exposure to a commercial PBDE mixture: effects on protein networks in the cerebellum and hippocampus of rats. Environmental Health Perspectives. 123: 428-36. PMID 25616259 DOI: 10.1289/ehp.1408504  0.8
2014 Alzate O, Osorio C, DeKroon RM, Corcimaru A, Gunawardena HP. Differentially charged isoforms of apolipoprotein E from human blood are potential biomarkers of Alzheimer's disease. Alzheimer's Research & Therapy. 6: 43. PMID 25478016 DOI: 10.1186/alzrt273  0.8
2014 Perez-Diaz S, Johnson LA, DeKroon RM, Moreno-Navarrete JM, Alzate O, Fernandez-Real JM, Maeda N, Arbones-Mainar JM. Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3769-79. PMID 24812087 DOI: 10.1096/fj.14-251165  0.8
2014 Hiller S, DeKroon R, Xu L, Robinette J, Winnik W, Alzate O, Simington S, Maeda N, Yi X. α-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice. Free Radical Biology & Medicine. 71: 362-7. PMID 24675228 DOI: 10.1016/j.freeradbiomed.2014.03.022  0.8
2014 Contreras MA, Alzate O, Singh AK, Singh I. PPARα activation induces N(ε)-Lys-acetylation of rat liver peroxisomal multifunctional enzyme type 1. Lipids. 49: 119-31. PMID 24092543 DOI: 10.1007/s11745-013-3843-x  0.8
2013 Rubel CE, Schisler JC, Hamlett ED, DeKroon RM, Gautel M, Alzate O, Patterson C. Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates. Cell Biochemistry and Biophysics. 67: 127-38. PMID 23695782 DOI: 10.1007/s12013-013-9624-6  0.8
2013 Klemcke HG, DeKroon RM, Mocanu M, Robinette JB, Alzate O. Cardiac mitochondrial proteomic expression in inbred rat strains divergent in survival time after hemorrhage. Physiological Genomics. 45: 243-55. PMID 23386204 DOI: 10.1152/physiolgenomics.00118.2012  0.8
2013 Florez AM, Osorio C, Alzate O. Protein Engineering of Bacillus thuringiensis δ-Endotoxins Bacillus Thuringiensis Biotechnology. 93-113. DOI: 10.1007/978-94-007-3021-2_5  0.8
2012 Londono C, Osorio C, Gama V, Alzate O. Mortalin, apoptosis, and neurodegeneration. Biomolecules. 2: 143-64. PMID 24970131 DOI: 10.3390/biom2010143  0.72
2012 Botero LE, Toro AE, Patiño AJ, Salazar G, Rodríguez JC, Suárez-Escudero JC, Alarcón GA, Corcimaru A, Osorio C, Jeong JS, Alzate O. Diabetes mellitus in patients with Alzheimer's disease: clinical description and correlation with the APOE genotype in a sample population from the province of Antioquia, Colombia. BioméDica : Revista Del Instituto Nacional De Salud. 32: 239-51. PMID 23242298 DOI: 10.1590/S0120-41572012000300012  0.8
2012 Londono C, DeKroon RM, Mocanu M, Booe J, Winnik WM, Swank A, Osorio C, Hamlett ED, Alzate O. Proteomic analysis of mice expressing human ApoE demonstrates no differences in global protein solubility between APOE 3 and APOE 4 young mice. Electrophoresis. 33: 3745-55. PMID 23161654 DOI: 10.1002/elps.201200219  0.8
2012 Haddad SE, Khoury M, Daoud M, Kantar R, Harati H, Mousallem T, Alzate O, Meyer B, Boustany RM. CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches. Electrophoresis. 33: 3798-809. PMID 23160995 DOI: 10.1002/elps.201200472  0.8
2012 Shannahan JH, Alzate O, Winnik WM, Andrews D, Schladweiler MC, Ghio AJ, Gavett SH, Kodavanti UP. Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure. Toxicology and Applied Pharmacology. 260: 105-14. PMID 22366155 DOI: 10.1016/j.taap.2012.02.006  0.8
2012 DeKroon RM, Robinette JB, Osorio C, Jeong JS, Hamlett E, Mocanu M, Alzate O. Analysis of protein posttranslational modifications using DIGE-based proteomics. Methods in Molecular Biology (Clifton, N.J.). 854: 129-43. PMID 22311757 DOI: 10.1007/978-1-61779-573-2_9  0.8
2012 Winnik WM, Dekroon RM, Jeong JS, Mocanu M, Robinette JB, Osorio C, Dicheva NN, Hamlett E, Alzate O. Analysis of proteins using DIGE and MALDI mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 854: 47-66. PMID 22311753 DOI: 10.1007/978-1-61779-573-2_5  0.8
2012 Onyenwoke RU, Forsberg LJ, Liu L, Williams T, Alzate O, Brenman JE. AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis. Molecular Biology of the Cell. 23: 381-9. PMID 22114351 DOI: 10.1091/mbc.E11-08-0699  0.8
2011 Kodavanti PR, Osorio C, Royland JE, Ramabhadran R, Alzate O. Aroclor 1254, a developmental neurotoxicant, alters energy metabolism- and intracellular signaling-associated protein networks in rat cerebellum and hippocampus. Toxicology and Applied Pharmacology. 256: 290-9. PMID 21791222 DOI: 10.1016/j.taap.2011.07.005  0.8
2011 DeKroon RM, Osorio C, Robinette JB, Mocanu M, Winnik WM, Alzate O. Simultaneous detection of changes in protein expression and oxidative modification as a function of age and APOE genotype. Journal of Proteome Research. 10: 1632-44. PMID 21210719 DOI: 10.1021/pr1009788  0.8
2010 Alzate O, Osorio C, Florez AM, Dean DH. Participation of valine 171 in alpha-Helix 5 of Bacillus thuringiensis Cry1Ab delta-endotoxin in translocation of toxin into Lymantria dispar midgut membranes. Applied and Environmental Microbiology. 76: 7878-80. PMID 20889788 DOI: 10.1128/AEM.01428-10  0.8
2009 Alzate O, Hemann CF, Osorio C, Hille R, Dean DH. Ser170 of Bacillus thuringiensis Cry1Ab delta-endotoxin becomes anchored in a hydrophobic moiety upon insertion of this protein into Manduca sexta brush border membranes. Bmc Biochemistry. 10: 25. PMID 19840388 DOI: 10.1186/1471-2091-10-25  0.8
2009 Sun B, Li S, Yang L, Damodaran T, Desai D, Diehl AM, Alzate O, Koeberl DD. Activation of glycolysis and apoptosis in glycogen storage disease type Ia. Molecular Genetics and Metabolism. 97: 267-71. PMID 19419892 DOI: 10.1016/j.ymgme.2009.04.003  0.8
2009 Sheikh AM, Barrett C, Villamizar N, Alzate O, Valente AM, Herlong JR, Craig D, Lodge A, Lawson J, Milano C, Jaggers J. Right ventricular hypertrophy with early dysfunction: A proteomics study in a neonatal model. The Journal of Thoracic and Cardiovascular Surgery. 137: 1146-53. PMID 19379982 DOI: 10.1016/j.jtcvs.2008.09.013  0.8
2009 Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD. Proteomic and immunologic analyses of brain tumor exosomes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1541-57. PMID 19109410 DOI: 10.1096/fj.08-122184  0.8
2008 Pinaud R, Osorio C, Alzate O, Jarvis ED. Profiling of experience-regulated proteins in the songbird auditory forebrain using quantitative proteomics. The European Journal of Neuroscience. 27: 1409-22. PMID 18364021 DOI: 10.1111/j.1460-9568.2008.06102.x  0.8
2008 You TH, Lee MK, Jenkins JL, Alzate O, Dean DH. Blocking binding of Bacillus thuringiensis Cry1Aa to Bombyx mori cadherin receptor results in only a minor reduction of toxicity. Bmc Biochemistry. 9: 3. PMID 18218126 DOI: 10.1186/1471-2091-9-3  0.8
2008 Osorno JB, Alzate O. Cardioproteomics: Perspectives and challenges | Cardioproteómica: Perspectivas y retos Revista Colombiana De Cardiologia. 15: 1-4.  0.8
2007 Osorio C, Sullivan PM, He DN, Mace BE, Ervin JF, Strittmatter WJ, Alzate O. Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. Neurobiology of Aging. 28: 1853-62. PMID 17050040 DOI: 10.1016/j.neurobiolaging.2006.08.011  0.8
2006 Alzate O, You T, Claybon M, Osorio C, Curtiss A, Dean DH. Effects of disulfide bridges in domain I of Bacillus thuringiensis Cry1Aa delta-endotoxin on ion-channel formation in biological membranes. Biochemistry. 45: 13597-605. PMID 17087513 DOI: 10.1021/bi061474z  0.8
2006 Sheikh AM, Barrett C, Villamizar N, Alzate O, Miller S, Shelburne J, Lodge A, Lawson J, Jaggers J. Proteomics of cerebral injury in a neonatal model of cardiopulmonary bypass with deep hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery. 132: 820-8. PMID 17000293 DOI: 10.1016/j.jtcvs.2006.07.002  0.8
2006 Padilla C, Pardo-López L, de la Riva G, Gómez I, Sánchez J, Hernandez G, Nuñez ME, Carey MP, Dean DH, Alzate O, Soberón M, Bravo A. Role of tryptophan residues in toxicity of Cry1Ab toxin from Bacillus thuringiensis. Applied and Environmental Microbiology. 72: 901-7. PMID 16391132 DOI: 10.1128/AEM.72.1.901-907.2006  0.8
2004 Alzate O, Hussain SR, Goettl VM, Tewari AK, Madiai F, Stephens RL, Hackshaw KV. Proteomic identification of brainstem cytosolic proteins in a neuropathic pain model. Brain Research. Molecular Brain Research. 128: 193-200. PMID 15363894 DOI: 10.1016/j.molbrainres.2004.06.037  0.8
2004 Goettl VM, Hussain SR, Alzate O, Wirtz DJ, Stephens RL, Hackshaw KV. Differential change in mRNA expression of p75 and Trk neurotrophin receptors in nucleus gracilis after spinal nerve ligation in the rat. Experimental Neurology. 187: 533-6. PMID 15144880 DOI: 10.1016/j.expneurol.2004.03.011  0.8
2004 Babu GJ, Wheeler D, Alzate O, Periasamy M. Solubilization of membrane proteins for two-dimensional gel electrophoresis: identification of sarcoplasmic reticulum membrane proteins. Analytical Biochemistry. 325: 121-5. PMID 14715292 DOI: 10.1016/j.ab.2003.10.024  0.8
2003 Abdullah MA, Alzate O, Mohammad M, McNall RJ, Adang MJ, Dean DH. Introduction of Culex toxicity into Bacillus thuringiensis Cry4Ba by protein engineering. Applied and Environmental Microbiology. 69: 5343-53. PMID 12957922 DOI: 10.1128/AEM.69.9.5343-5353.2003  0.8
2001 Alcantara EP, Alzate O, Lee MK, Curtiss A, Dean DH. Role of alpha-helix seven of Bacillus thuringiensis Cry1Ab delta-endotoxin in membrane insertion, structural stability, and ion channel activity. Biochemistry. 40: 2540-7. PMID 11327876 DOI: 10.1021/bi0022240  0.8
2001 Gutierrez P, Alzate O, Orduz S. A theoretical model of the tridimensional structure of Bacillus thuringiensis subsp. medellin Cry 11Bb toxin deduced by homology modelling. MemóRias Do Instituto Oswaldo Cruz. 96: 357-64. PMID 11313644  0.8
2001 Arnold S, Curtiss A, Dean DH, Alzate O. The role of a proline-induced broken-helix motif in alpha-helix 2 of Bacillus thuringiensis delta-endotoxins. Febs Letters. 490: 70-4. PMID 11172813 DOI: 10.1016/S0014-5793(01)02139-1  0.8
1999 Audtho M, Valaitis AP, Alzate O, Dean DH. Production of chymotrypsin-resistant Bacillus thuringiensis Cry2Aa1 delta-endotoxin by protein engineering. Applied and Environmental Microbiology. 65: 4601-5. PMID 10508095  0.8
1996 Rajamohan F, Alzate O, Cotrill JA, Curtiss A, Dean DH. Protein engineering of Bacillus thuringiensis delta-endotoxin: mutations at domain II of CryIAb enhance receptor affinity and toxicity toward gypsy moth larvae. Proceedings of the National Academy of Sciences of the United States of America. 93: 14338-43. PMID 8962052 DOI: 10.1073/pnas.93.25.14338  0.8
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