Ellen Unterwald - Publications

Affiliations: 
Temple Univ Sch Med, Philadelphia, PA, United States 
Area:
neuropharmacology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rivera CC, Price R, Fortuna RP, Li C, Do C, Shinkle J, Ghilotti MG, Shi X, Kirby LG, Smith GM, Unterwald EM. The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. Biorxiv : the Preprint Server For Biology. PMID 38076811 DOI: 10.1101/2023.11.29.569314  0.303
2022 Shi X, von Weltin E, Fitzsimmons E, Do C, Caban Rivera C, Chen C, Liu-Chen LY, Unterwald EM. Reactivation of cocaine contextual memory engages mechanistic target of rapamycin/S6 kinase 1 signaling. Frontiers in Pharmacology. 13: 976932. PMID 36238569 DOI: 10.3389/fphar.2022.976932  0.36
2020 Connelly KL, Wolsh CC, Barr JL, Bauder M, Hausch F, Unterwald EM. Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration. Neurobiology of Stress. 13: 100232. PMID 33344688 DOI: 10.1016/j.ynstr.2020.100232  0.436
2020 Swinford-Jackson SE, O'Brien CP, Kenny PJ, Vanderschuren LJMJ, Unterwald EM, Pierce RC. The Persistent Challenge of Developing Addiction Pharmacotherapies. Cold Spring Harbor Perspectives in Medicine. PMID 32601131 DOI: 10.1101/cshperspect.a040311  0.352
2020 Connelly KL, Wolsh CC, Barr JL, Bauder M, Hausch F, Unterwald EM. Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration Neurobiology of Stress. 13: 100232. DOI: 10.1016/J.Ynstr.2020.100232  0.436
2019 Connelly KL, Unterwald EM. Regulation of CRF mRNA in the rat extended amygdala following chronic cocaine: sex differences and effect of delta opioid receptor agonism. The International Journal of Neuropsychopharmacology. PMID 31867624 DOI: 10.1093/ijnp/pyz067  0.516
2019 Barr JL, Brailoiu GC, Abood ME, Rawls SM, Unterwald EM, Brailoiu E. Acute cocaine administration alters permeability of blood-brain barrier in freely-moving rats- Evidence using miniaturized fluorescence microscopy. Drug and Alcohol Dependence. 107637. PMID 31734036 DOI: 10.1016/J.Drugalcdep.2019.107637  0.416
2019 Shi X, Barr JL, von Weltin E, Wolsh C, Unterwald EM. Role of accumbal GSK3β in drug reward, aversion, and place memory. The Journal of Pharmacology and Experimental Therapeutics. PMID 31420527 DOI: 10.1124/Jpet.119.259283  0.435
2019 Denny RR, Unterwald EM. Clonidine, an α2 adrenergic receptor agonist, disrupts reconsolidation of a cocaine-paired environmental memory. Behavioural Pharmacology. 30: 529-533. PMID 31386639 DOI: 10.1097/FBP.0000000000000473  0.442
2019 Shi X, von Weltin E, Barr JL, Unterwald EM. Activation of GSK3β induced by recall of cocaine reward memories is dependent on GluN2A/B NMDA receptor signaling. Journal of Neurochemistry. PMID 31361029 DOI: 10.1111/Jnc.14842  0.418
2019 Connelly KL, Unterwald EM. Chronic cocaine administration upregulates FKBP5 in the extended amygdala of male and female rats. Drug and Alcohol Dependence. 199: 101-105. PMID 31029877 DOI: 10.1016/j.drugalcdep.2019.02.019  0.423
2016 Kim J, Connelly KL, Unterwald EM, Rawls SM. Chemokines and cocaine: CXCR4 receptor antagonist AMD3100 attenuates cocaine place preference and locomotor stimulation in rats. Brain, Behavior, and Immunity. PMID 27575003 DOI: 10.1016/J.Bbi.2016.08.015  0.503
2015 Brailoiu GC, Deliu E, Console Bram LM, Soboloff J, Abood ME, Unterwald EM, Brailoiu E. Cocaine Inhibits Store-Operated Ca2+ Entry in Brain Microvascular Endothelial Cells: Critical Role for Sigma-1 Receptors. The Biochemical Journal. PMID 26467159 DOI: 10.1042/Bj20150934  0.32
2015 Barr JL, Rasmussen BA, Tallarida CS, Scholl JL, Forster GL, Unterwald EM, Rawls SM. Ceftriaxone attenuates acute cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens of the rat. British Journal of Pharmacology. PMID 26375494 DOI: 10.1111/Bph.13330  0.423
2015 Enman NM, Arthur K, Ward SJ, Perrine SA, Unterwald EM. Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder. Biological Psychiatry. PMID 26115790 DOI: 10.1016/j.biopsych.2015.04.024  0.636
2015 Barr JL, Deliu E, Brailoiu GC, Zhao P, Yan G, Abood ME, Unterwald EM, Brailoiu E. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell Calcium. 58: 196-207. PMID 26077147 DOI: 10.1016/J.Ceca.2015.05.001  0.45
2015 Craige CP, Lewandowski S, Kirby LG, Unterwald EM. Dorsal raphe 5-HT(2C) receptor and GABA networks regulate anxiety produced by cocaine withdrawal. Neuropharmacology. 93: 41-51. PMID 25656481 DOI: 10.1016/J.Neuropharm.2015.01.021  0.436
2015 Barr JL, Unterwald EM. Activity-regulated gene expression in immature neurons in the dentate gyrus following re-exposure to a cocaine-paired environment. Hippocampus. 25: 354-62. PMID 25294309 DOI: 10.1002/Hipo.22377  0.352
2015 Barr JL, Rassmussen BA, Tallarida CS, Scholl JL, Forster GL, Unterwald E, Rawls S. Ceftriaxone attenuates acute cocaine evoked motor activity and dopaminergic neurotransmission in the dorsal and ventral striatum Drug and Alcohol Dependence. 156: e15. DOI: 10.1016/J.Drugalcdep.2015.07.960  0.467
2014 Parikh V, Naughton SX, Shi X, Kelley LK, Yegla B, Tallarida CS, Rawls SM, Unterwald EM. Cocaine-induced neuroadaptations in the dorsal striatum: glutamate dynamics and behavioral sensitization. Neurochemistry International. 75: 54-65. PMID 24911954 DOI: 10.1016/J.Neuint.2014.05.016  0.418
2014 Barr JL, Forster GL, Unterwald EM. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of Neurochemistry. 130: 583-90. PMID 24832868 DOI: 10.1111/Jnc.12764  0.47
2014 Shi X, Miller JS, Harper LJ, Poole RL, Gould TJ, Unterwald EM. Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition. Psychopharmacology. 231: 3109-18. PMID 24595501 DOI: 10.1007/s00213-014-3491-8  0.338
2014 Miller JS, Barr JL, Harper LJ, Poole RL, Gould TJ, Unterwald EM. The GSK3 signaling pathway is activated by cocaine and is critical for cocaine conditioned reward in mice. Plos One. 9: e88026. PMID 24505362 DOI: 10.1371/Journal.Pone.0088026  0.482
2014 Barr JL, Forster G, Unterwald E. Adaptation of the hippocampus-accumbens pathway following repeated cocaine Drug and Alcohol Dependence. 140: e11. DOI: 10.1016/J.Drugalcdep.2014.02.051  0.303
2013 Xu W, Wang Y, Ma Z, Chiu YT, Huang P, Rasakham K, Unterwald E, Lee DY, Liu-Chen LY. L-isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors. Drug and Alcohol Dependence. 133: 693-703. PMID 24080315 DOI: 10.1016/j.drugalcdep.2013.08.021  0.433
2013 Xu W, Chen C, Li JG, Dimattio K, Wang Y, Unterwald E, Liu-Chen LY. PKA and ERK1/2 are involved in dopamine D₁ receptor-induced heterologous desensitization of the δ opioid receptor. Life Sciences. 92: 1101-9. PMID 23624231 DOI: 10.1016/j.lfs.2013.04.006  0.485
2013 Craige CP, Unterwald EM. Serotonin (2C) receptor regulation of cocaine-induced conditioned place preference and locomotor sensitization. Behavioural Brain Research. 238: 206-10. PMID 23103406 DOI: 10.1016/J.Bbr.2012.10.034  0.446
2013 Craige CP, Enman NM, Unterwald EM. Stress, Anxiety, and Cocaine Abuse The Effects of Drug Abuse On the Human Nervous System. 135-167. DOI: 10.1016/B978-0-12-418679-8.00006-X  0.359
2012 Reith ME, Ali S, Hashim A, Sheikh IS, Theddu N, Gaddiraju NV, Mehrotra S, Schmitt KC, Murray TF, Sershen H, Unterwald EM, Davis FA. Novel C-1 substituted cocaine analogs unlike cocaine or benztropine. The Journal of Pharmacology and Experimental Therapeutics. 343: 413-25. PMID 22895898 DOI: 10.1124/Jpet.112.193771  0.426
2012 Enman NM, Unterwald EM. Inhibition of GSK3 attenuates amphetamine-induced hyperactivity and sensitization in the mouse. Behavioural Brain Research. 231: 217-25. PMID 22649795 DOI: 10.1016/j.bbr.2012.03.027  0.329
2011 Rasmussen B, Unterwald EM, Rawls SM. Glutamate transporter subtype 1 (GLT-1) activator ceftriaxone attenuates amphetamine-induced hyperactivity and behavioral sensitization in rats. Drug and Alcohol Dependence. 118: 484-8. PMID 21524862 DOI: 10.1016/J.Drugalcdep.2011.03.022  0.401
2010 Nwaneshiudu CA, Unterwald EM. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of Neurochemistry. 115: 635-42. PMID 20807318 DOI: 10.1111/j.1471-4159.2010.06973.x  0.492
2010 Randall-Thompson JF, Pescatore KA, Unterwald EM. A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors. Psychopharmacology. 212: 585-95. PMID 20730419 DOI: 10.1007/s00213-010-1980-y  0.326
2010 Carvalho AF, Reyes AR, Sterling RC, Unterwald E, Van Bockstaele EJ. Contribution of limbic norepinephrine to cannabinoid-induced aversion. Psychopharmacology. 211: 479-91. PMID 20602088 DOI: 10.1007/S00213-010-1923-7  0.431
2010 Walsh SL, Unterwald EM, Izenwasser S. Introduction to the College on Problems of Drug Dependence special issue: contemporary advances in opioid neuropharmacology. Drug and Alcohol Dependence. 108: 153-5. PMID 20378280 DOI: 10.1016/J.Drugalcdep.2010.03.001  0.592
2010 Miller JS, Tallarida RJ, Unterwald EM. Inhibition of GSK3 attenuates dopamine D1 receptor agonist-induced hyperactivity in mice. Brain Research Bulletin. 82: 184-7. PMID 20347018 DOI: 10.1016/j.brainresbull.2010.03.005  0.308
2010 Trecki J, Brailoiu GC, Unterwald EM. Localization of CXCR4 in the forebrain of the adult rat. Brain Research. 1315: 53-62. PMID 20026091 DOI: 10.1016/j.brainres.2009.12.015  0.316
2009 Soderman AR, Unterwald EM. Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain Research. 1296: 63-71. PMID 19699185 DOI: 10.1016/j.brainres.2009.08.035  0.529
2009 Zakharova E, Miller J, Unterwald E, Wade D, Izenwasser S. Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats. Neuroscience. 163: 890-7. PMID 19580849 DOI: 10.1016/J.Neuroscience.2009.06.068  0.685
2009 Schroeder JA, McCafferty MR, Unterwald EM. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). 63: 863-70. PMID 19562697 DOI: 10.1002/syn.20669  0.501
2009 Nwaneshiudu CA, Unterwald EM. Blockade of neurokinin-3 receptors modulates dopamine-mediated behavioral hyperactivity. Neuropharmacology. 57: 295-301. PMID 19500601 DOI: 10.1016/j.neuropharm.2009.05.008  0.422
2009 Rasmussen BA, Kim E, Unterwald EM, Rawls SM. Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB1-dopamine D2 receptor mechanism. Brain Research. 1260: 7-14. PMID 19401177 DOI: 10.1016/J.Brainres.2008.12.078  0.465
2009 Miller JS, Tallarida RJ, Unterwald EM. Cocaine-induced hyperactivity and sensitization are dependent on GSK3. Neuropharmacology. 56: 1116-23. PMID 19328817 DOI: 10.1016/j.neuropharm.2009.03.006  0.459
2009 Trecki J, Unterwald EM. Modulation of cocaine-induced activity by intracerebral administration of CXCL12. Neuroscience. 161: 13-22. PMID 19303923 DOI: 10.1016/j.neuroscience.2009.03.027  0.509
2008 Perrine SA, Miller JS, Unterwald EM. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of Neurochemistry. 107: 570-7. PMID 18717814 DOI: 10.1111/j.1471-4159.2008.05632.x  0.7
2008 Soderman AR, Unterwald EM. Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience. 154: 1506-16. PMID 18550291 DOI: 10.1016/j.neuroscience.2008.04.063  0.556
2008 Ambrose-Lanci LM, Peiris NB, Unterwald EM, Van Bockstaele EJ. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain Research. 1210: 92-102. PMID 18417105 DOI: 10.1016/j.brainres.2008.02.105  0.514
2008 Tropea TF, Guerriero RM, Willuhn I, Unterwald EM, Ehrlich ME, Steiner H, Kosofsky BE. Augmented D1 dopamine receptor signaling and immediate-early gene induction in adult striatum after prenatal cocaine. Biological Psychiatry. 63: 1066-74. PMID 18275938 DOI: 10.1016/J.Biopsych.2007.12.002  0.459
2008 Niculescu M, Perrine SA, Miller JS, Ehrlich ME, Unterwald EM. Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1198-207. PMID 18234897 DOI: 10.1523/Jneurosci.0988-07.2008  0.702
2008 Perrine SA, Sheikh IS, Nwaneshiudu CA, Schroeder JA, Unterwald EM. Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat. Neuropharmacology. 54: 355-64. PMID 18045627 DOI: 10.1016/j.neuropharm.2007.10.007  0.721
2007 Schroeder JA, Hummel M, Simpson AD, Sheikh R, Soderman AR, Unterwald EM. A role for mu opioid receptors in cocaine-induced activity, sensitization, and reward in the rat. Psychopharmacology. 195: 265-72. PMID 17687547 DOI: 10.1007/s00213-007-0883-z  0.554
2006 Hummel M, Schroeder J, Liu-Chen LY, Cowan A, Unterwald EM. An antisense oligodeoxynucleotide to the mu opioid receptor attenuates cocaine-induced behavioral sensitization and reward in mice. Neuroscience. 142: 481-91. PMID 16893609 DOI: 10.1016/J.Neuroscience.2006.06.013  0.471
2006 Ambrose LM, Gallagher SM, Unterwald EM, Van Bockstaele EJ. Dopamine-D1 and delta-opioid receptors co-exist in rat striatal neurons. Neuroscience Letters. 399: 191-6. PMID 16517070 DOI: 10.1016/j.neulet.2006.02.027  0.435
2006 Perrine SA, Hoshaw BA, Unterwald EM. Delta opioid receptor ligands modulate anxiety-like behaviors in the rat. British Journal of Pharmacology. 147: 864-72. PMID 16491101 DOI: 10.1038/Sj.Bjp.0706686  0.682
2005 Muller DL, Unterwald EM. D1 dopamine receptors modulate deltaFosB induction in rat striatum after intermittent morphine administration. The Journal of Pharmacology and Experimental Therapeutics. 314: 148-54. PMID 15772255 DOI: 10.1124/jpet.105.083410  0.412
2005 Perrine SA, Schroeder JA, Unterwald EM. Behavioral sensitization to binge-pattern cocaine administration is not associated with changes in protein levels of four major G-proteins. Brain Research. Molecular Brain Research. 133: 224-32. PMID 15710239 DOI: 10.1016/j.molbrainres.2004.10.025  0.696
2004 McCarthy LE, Mannelli P, Niculescu M, Gingrich K, Unterwald EM, Ehrlich ME. The distribution of cocaine in mice differs by age and strain. Neurotoxicology and Teratology. 26: 839-48. PMID 15451047 DOI: 10.1016/J.Ntt.2004.07.004  0.392
2004 Schroeder JA, Hummel M, Unterwald EM. Disruption of G(i/o) protein signaling in the nucleus accumbens results in a D1 dopamine receptor-mediated hyperactivity. Pharmacology, Biochemistry, and Behavior. 79: 93-9. PMID 15388288 DOI: 10.1016/j.pbb.2004.06.004  0.411
2004 Ambrose LM, Unterwald EM, Van Bockstaele EJ. Ultrastructural evidence for co-localization of dopamine D2 and micro-opioid receptors in the rat dorsolateral striatum. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 279: 583-91. PMID 15224400 DOI: 10.1002/ar.a.20054  0.487
2004 Schroeder JA, Hummel M, Unterwald EM. Repeated intracerebroventricular forskolin administration enhances behavioral sensitization to cocaine. Behavioural Brain Research. 153: 255-60. PMID 15219727 DOI: 10.1016/j.bbr.2003.12.005  0.482
2004 Muller DL, Unterwald EM. In vivo regulation of extracellular signal-regulated protein kinase (ERK) and protein kinase B (Akt) phosphorylation by acute and chronic morphine. The Journal of Pharmacology and Experimental Therapeutics. 310: 774-82. PMID 15056728 DOI: 10.1124/jpet.104.066548  0.312
2004 Hummel M, Ansonoff MA, Pintar JE, Unterwald EM. Genetic and pharmacological manipulation of mu opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine. Neuroscience. 125: 211-20. PMID 15051160 DOI: 10.1016/J.Neuroscience.2004.01.025  0.435
2003 Unterwald EM, Ivkovic S, Cuntapay M, Stroppolo A, Guinea B, Ehrlich ME. Prenatal exposure to cocaine decreases adenylyl cyclase activity in embryonic mouse striatum. Brain Research. Developmental Brain Research. 147: 67-75. PMID 14741752 DOI: 10.1016/S0165-3806(03)00058-0  0.443
2003 Hummel M, Unterwald EM. Intra-accumbens pertussis toxin sensitizes rats to the locomotor activating effects of a single cocaine challenge. Brain Research. 965: 100-7. PMID 12591125 DOI: 10.1016/S0006-8993(02)04142-2  0.483
2003 Kruzich PJ, Chen AC, Unterwald EM, Kreek MJ. Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding. Synapse (New York, N.Y.). 47: 243-9. PMID 12539196 DOI: 10.1002/Syn.10173  0.307
2003 Schroeder JA, Niculescu M, Unterwald EM. Cocaine alters mu but not delta or kappa opioid receptor-stimulated in situ [35S]GTPgammaS binding in rat brain. Synapse (New York, N.Y.). 47: 26-32. PMID 12422370 DOI: 10.1002/syn.10148  0.55
2002 Ehrlich ME, Sommer J, Canas E, Unterwald EM. Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9155-9. PMID 12417638  0.354
2002 Hummel M, Unterwald EM. D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action. Journal of Cellular Physiology. 191: 17-27. PMID 11920678 DOI: 10.1002/jcp.10078  0.462
2001 Kushner SA, Unterwald EM. Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding. Life Sciences. 69: 1093-102. PMID 11508652 DOI: 10.1016/S0024-3205(01)01203-6  0.443
2001 Unterwald EM. Regulation of opioid receptors by cocaine. Annals of the New York Academy of Sciences. 937: 74-92. PMID 11458541  0.519
2001 Unterwald EM, Kreek MJ, Cuntapay M. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain Research. 900: 103-9. PMID 11325352 DOI: 10.1016/S0006-8993(01)02269-7  0.516
2000 Unterwald EM, Cuntapay M. Dopamine-opioid interactions in the rat striatum: a modulatory role for dopamine D1 receptors in delta opioid receptor-mediated signal transduction. Neuropharmacology. 39: 372-81. PMID 10698003 DOI: 10.1016/S0028-3908(99)00154-9  0.366
1999 Zhu Y, King MA, Schuller AG, Nitsche JF, Reidl M, Elde RP, Unterwald E, Pasternak GW, Pintar JE. Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice. Neuron. 24: 243-52. PMID 10677041 DOI: 10.1016/S0896-6273(00)80836-3  0.364
1998 Perret G, Schluger JH, Unterwald EM, Kreuter J, Ho A, Kreek MJ. Downregulation of 5-HT1A receptors in rat hypothalamus and dentate gyrus after "binge" pattern cocaine administration. Synapse (New York, N.Y.). 30: 166-71. PMID 9723786 DOI: 10.1002/(Sici)1098-2396(199810)30:2<166::Aid-Syn6>3.0.Co;2-A  0.483
1998 Unterwald EM, Anton B, To T, Lam H, Evans CJ. Quantitative immunolocalization of mu opioid receptors: regulation by naltrexone. Neuroscience. 85: 897-905. PMID 9639282 DOI: 10.1016/S0306-4522(97)00659-3  0.359
1998 Maggos CE, Tsukada H, Kakiuchi T, Nishiyama S, Myers JE, Kreuter J, Schlussman SD, Unterwald EM, Ho A, Kreek MJ. Sustained withdrawal allows normalization of in vivo [11C]N-methylspiperone dopamine D2 receptor binding after chronic binge cocaine: a positron emission tomography study in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 146-53. PMID 9629568 DOI: 10.1016/S0893-133X(98)00009-8  0.385
1996 Unterwald EM, Fillmore J, Kreek MJ. Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction. European Journal of Pharmacology. 318: 31-5. PMID 9007509 DOI: 10.1016/S0014-2999(96)00841-2  0.476
1996 Tsukada H, Kreuter J, Maggos CE, Unterwald EM, Kakiuchi T, Nishiyama S, Futatsubashi M, Kreek MJ. Effects of binge pattern cocaine administration on dopamine D1 and D2 receptors in the rat brain: an in vivo study using positron emission tomography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7670-7. PMID 8922423 DOI: 10.1523/Jneurosci.16-23-07670.1996  0.413
1996 Donovan DM, Miner LL, Sharpe L, Cho HJ, Takemura M, Unterwald E, Nyberg F, Kreek MJ, Uhl GR. Transgenic mice: preproenkephalin and the mu opiate receptor. Annals of the New York Academy of Sciences. 780: 19-28. PMID 8602733 DOI: 10.1111/J.1749-6632.1996.Tb15108.X  0.313
1995 Unterwald EM, Rubenfeld JM, Imai Y, Wang JB, Uhl GR, Kreek MJ. Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels. Brain Research. Molecular Brain Research. 33: 351-5. PMID 8750897 DOI: 10.1016/0169-328X(95)00143-G  0.37
1995 Unterwald EM, Rubenfeld JM, Kreuter J, Kreek MJ. MU OPIOID RECEPTOR mRNA LEVELS FOLLOWING CHRONIC ADMINISTRATION OF OPIOID LIGANDS Analgesia. 1: 805-808. DOI: 10.3727/107156995819563663  0.313
1994 Unterwald EM. Anatomy of addiction. Science (New York, N.Y.). 263: 1456-7. PMID 17776516 DOI: 10.1126/science.263.5152.1456  0.303
1994 Unterwald EM, Ho A, Rubenfeld JM, Kreek MJ. Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration. The Journal of Pharmacology and Experimental Therapeutics. 270: 1387-96. PMID 7932193  0.498
1994 Unterwald EM, Rubenfeld JM, Kreek MJ. Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors. Neuroreport. 5: 1613-6. PMID 7819531 DOI: 10.1097/00001756-199408150-00018  0.541
1994 Unterwald EM, Rubenfeld JM, Spangler R, Imai Y, Wang JB, Uhl GR, Kreek MJ. Mu opioid receptor mRNA levels following chronic naltrexone administration Regulatory Peptides. 54: 307-308. DOI: 10.1016/0167-0115(94)90512-6  0.318
1994 Spangler R, Zhou Y, Unterwald E, Yuferov V, Ho A, Kreek MJ. Kappa opioid receptor mRNA levels in the rat brain: Effects of dopamine antagonists and cocaine Regulatory Peptides. 54: 283-284. DOI: 10.1016/0167-0115(94)90500-2  0.59
1994 Unterwald E, Kreek MJ. Kappa and delta opioid receptor densities following chronic repeated cocaine administration Regulatory Peptides. 53: S225-S226. DOI: 10.1016/0167-0115(94)90322-0  0.571
1994 Adams JU, Izenwasser S, Kramer TH, Stevens CW, Tiseo PJ, Unterwald EM. Tolerance and sensitization to opioids and cocaine Nida Research Monograph Series. 69-73.  0.675
1993 Unterwald EM, Cox BM, Kreek MJ, Cote TE, Izenwasser S. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). 15: 33-8. PMID 8310423 DOI: 10.1002/Syn.890150104  0.725
1993 Spangler R, Unterwald EM, Kreek MJ. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Brain Research. Molecular Brain Research. 19: 323-7. PMID 7694032 DOI: 10.1016/0169-328X(93)90133-A  0.443
1993 Izenwasser S, Unterwald EM, Cote TE, Cox BM, Kreek MJ. Repeated, daily cocaine administration produces changes in basal and opioid-regulated adenylyl cyclase activity in rat caudate-putamen and nucleus accubens Nida Research Monograph Series. 392.  0.702
1993 Spangler R, Unterwald EM, Branch AD, Ho A, Kreek MJ. Chronic cocaine administration increases mRNA levels for dynorphin in the caudate putamen of rats Nida Research Monograph Series. 142.  0.416
1992 Unterwald EM, Horne-King J, Kreek MJ. Chronic cocaine alters brain mu opioid receptors. Brain Research. 584: 314-8. PMID 1325249 DOI: 10.1016/0006-8993(92)90912-S  0.529
1992 Branch AD, Unterwald EM, Lee SE, Kreek MJ. Quantitation of preproenkephalin mRNA levels in brain regions from male Fischer rats following chronic cocaine treatment using a recently developed solution hybridization assay. Brain Research. Molecular Brain Research. 14: 231-8. PMID 1279343 DOI: 10.1016/0169-328X(92)90178-E  0.34
1991 Unterwald EM, Knapp C, Zukin RS. Neuroanatomical localization of kappa 1 and kappa 2 opioid receptors in rat and guinea pig brain. Brain Research. 562: 57-65. PMID 1666016 DOI: 10.1016/0006-8993(91)91186-5  0.572
1990 Unterwald EM, Kreek MJ. Alterations in the expression of brain opioid receptors during senescence New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 200.  0.317
1989 Unterwald EM, Tempel A, Koob GF, Zukin RS. Characterization of opioid receptors in rat nucleus accumbens following mesolimbic dopaminergic lesions. Brain Research. 505: 111-8. PMID 2558779 DOI: 10.1016/0006-8993(89)90120-0  0.604
1988 Kornetsky C, Bain GT, Unterwald EM, Lewis MJ. Brain stimulation reward: effects of ethanol. Alcoholism, Clinical and Experimental Research. 12: 609-16. PMID 2852475 DOI: 10.1111/J.1530-0277.1988.Tb00250.X  0.559
1988 Zukin RS, Eghbali M, Olive D, Unterwald EM, Tempel A. Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors. Proceedings of the National Academy of Sciences of the United States of America. 85: 4061-5. PMID 2836869  0.577
1987 Unterwald E, Sasson S, Kornetsky C. Evaluation of the supraspinal analgesic activity and abuse liability of ethylketocyclazocine. European Journal of Pharmacology. 133: 275-81. PMID 3030776 DOI: 10.1016/0014-2999(87)90023-9  0.636
1986 Unterwald EM, Kornetsky C. Effects of nalbuphine alone and in combination with tripelennamine on rewarding brain stimulation thresholds in the rat. Pharmacology, Biochemistry, and Behavior. 25: 629-32. PMID 3774829 DOI: 10.1016/0091-3057(86)90152-8  0.633
1986 Sasson S, Unterwald EM, Kornetsky C. Potentiation of morphine analgesia by d-amphetamine. Psychopharmacology. 90: 163-5. PMID 3097695 DOI: 10.1007/Bf00181233  0.578
1984 Unterwald EM, Kucharski LT, Williams JE, Kornetsky C. Tripelennamine: enhancement of brain-stimulation reward. Life Sciences. 34: 149-53. PMID 6607395 DOI: 10.1016/0024-3205(84)90585-X  0.66
1984 Unterwald EM, Kornetsky C. Effects of concomitant pentazocine and tripelennamine on brain-stimulation reward. Pharmacology, Biochemistry, and Behavior. 21: 961-4. PMID 6335254 DOI: 10.1016/S0091-3057(84)80080-5  0.608
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