James Appel - Related publications

University of South Carolina, Columbia, SC 
Behavioral Neuropharmacology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Li D, Park S, Lee K, Jang DS, Kim SK. 5-HT receptors mediate the analgesic effect of rosavin in a mouse model of oxaliplatin-induced peripheral neuropathic pain. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 25: 489-494. PMID 34448466 DOI: 10.4196/kjpp.2021.25.5.489   
2021 Zhao Y, Chen S, Huai X, Yu Z, Qi Y, Qing J, Yu W, Su D. Efficiency and Safety of the Selective Relaxant Binding Agent Adamgammadex Sodium for Reversing Rocuronium-Induced Deep Neuromuscular Block: A Single-Center, Open-Label, Dose-Finding, and Phase IIa Study. Frontiers in Medicine. 8: 697395. PMID 34513870 DOI: 10.3389/fmed.2021.697395   
2021 Varshneya NB, Walentiny DM, Moisa LT, Walker TD, Akinfiresoye LR, Beardsley PM. Fentanyl-related substances elicit antinociception and hyperlocomotion in mice via opioid receptors. Pharmacology, Biochemistry, and Behavior. 173242. PMID 34302853 DOI: 10.1016/j.pbb.2021.173242   
2021 Sabe M, Zhao N, Crippa A, Kaiser S. Antipsychotics for negative and positive symptoms of schizophrenia: dose-response meta-analysis of randomized controlled acute phase trials. Npj Schizophrenia. 7: 43. PMID 34518532 DOI: 10.1038/s41537-021-00171-2   
2021 Miller L, Hébert CD, Grimes SD, Toomey JS, Oh JY, Rose JJ, Patel RP. Safety and toxicology assessment of sodium nitrite administered by intramuscular injection. Toxicology and Applied Pharmacology. 115702. PMID 34464673 DOI: 10.1016/j.taap.2021.115702   
2021 Madden JT, Reyna NC, Goranson EV, Gonzalez TA, Zavala AR, Pentkowski NS. Blocking serotonin 2A (5-HT) receptors attenuates the acquisition of methamphetamine-induced conditioned place preference in adult female rats. Behavioural Brain Research. 415: 113521. PMID 34391796 DOI: 10.1016/j.bbr.2021.113521   
2021 Salemi LA, Sahlstrom AL, Lim SY, Johnson PN, Dannaway D, Miller JL. Evaluation of the Use of Caffeine Citrate Maintenance Doses >5 mg/kg/day in Preterm Neonates for Apnea of Prematurity. The Journal of Pediatric Pharmacology and Therapeutics : Jppt : the Official Journal of Ppag. 26: 608-614. PMID 34421411 DOI: 10.5863/1551-6776-26.6.608   
2021 Zhang Y, Zhang J, Shi B, Li B, Du Z, Wang J, Zhu L, Wang J. Effects of cloransulam-methyl and diclosulam on soil nitrogen and carbon cycle-related microorganisms. Journal of Hazardous Materials. 418: 126395. PMID 34329028 DOI: 10.1016/j.jhazmat.2021.126395   
2021 Sarturi V, Teixeira L, Coradini G, Milech V, Hartmann H, Linhares M, Martins L, de Oliveira J, Brun M. Total intravenous anesthesia with propofol associated or not with remifentanil, ketamine, or S-ketamine for laparoscopic ovariectomy in female dogs. Topics in Companion Animal Medicine. 100575. PMID 34400382 DOI: 10.1016/j.tcam.2021.100575   
2021 Won H, Jeong DH, Shin HS, Lee JH, Lee JP, Yang JY, Jung K, Jeong J, Oh JH. Toxicological Assessment of Bromochlorophene: Single and Repeated-Dose 28-Day Oral Toxicity, Genotoxicity, and Dermal Application in Sprague-Dawley Rats. Frontiers in Pharmacology. 12: 690141. PMID 34335256 DOI: 10.3389/fphar.2021.690141   
2021 Dehpour AR, Yousefi-Manesh H, Sheibani M, Sadeghi MA, Hemmati S, Noori T, Shirooie S. Evaluation of Anti-inflammatory and Antioxidant Effects of Sumatriptan on Carbon Tetrachloride-induced Hepatotoxicity in Rats. Drug Research. PMID 34500479 DOI: 10.1055/a-1589-5395   
2021 Marti M, Talani G, Miliano C, Bilel S, Biggio F, Bratzu J, Diana M, Fadda P, De Luca MA, Fattore L. New insights into methoxetamine mechanisms of action: Focus on serotonergic 5HT-2 receptors in pharmacological and behavioral effects in the rat. Experimental Neurology. 113836. PMID 34384790 DOI: 10.1016/j.expneurol.2021.113836   
2021 Adebayo AH, Ishola TA, Yakubu OF. Acute toxicity and antimalarial studies of extract of  in animals. Toxicological Research. 37: 345-354. PMID 34295798 DOI: 10.1007/s43188-020-00070-1   
2021 Chai LF, Hardaway JC, Heatherton KR, O'Connell KP, Lopes MC, Rabinowitz BA, Ghosh CC, Guha P, Jaroch D, Cox BF, Katz SC. Regional Delivery of Anti-PD-1 Agent for Colorectal Liver Metastases Improves Therapeutic Index and Anti-Tumor Activity. Vaccines. 9. PMID 34451932 DOI: 10.3390/vaccines9080807   
2021 Zhang Z, Du X, Bai H, Shen M, Ma X, Li R, Jin X, Gao L. Cardiopulmonary (No Ventilation) and Anesthetic Effects of Dexmedetomidine-Tiletamine in Dogs. Frontiers in Veterinary Science. 8: 674862. PMID 34336971 DOI: 10.3389/fvets.2021.674862   
2021 Santos MVD, Goes RHTB, Takiya CS, Cabral LDS, Mombach MA, Oliveira RT, Silva NGD, Anschau DG, Freitas Júnior JE, de Araújo MLGML, Gandra JR. Effect of increasing doses of chitosan to grazing beef steers on the relative population and transcript abundance of and cellulolytic and amylolytic bacterias. Animal Biotechnology. 1-7. PMID 34346295 DOI: 10.1080/10495398.2021.1954936   
2021 Maliyakkal N, Saleem U, Anwar F, Shah MA, Ahmad B, Umer F, Almoyad MAA, Parambi DGT, Beeran AA, Nath LR, Aleya L, Mathew B. Ameliorative effect of ethoxylated chalcone-based MAO-B inhibitor on behavioural predictors of haloperidol-induced Parkinsonism in mice: evidence of its antioxidative role against Parkinson's diseases. Environmental Science and Pollution Research International. PMID 34476688 DOI: 10.1007/s11356-021-15955-3   
2021 Cheng PNM, Liu AM, Bessudo A, Mussai F. Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors. Investigational New Drugs. PMID 34287772 DOI: 10.1007/s10637-021-01149-8   
2021 Oyewopo AO, Adeleke O, Johnson O, Akingbade A, Olaniyi KS, Areola ED, Tokunbo O. Regulatory effects of quercetin on testicular histopathology induced by cyanide in Wistar rats. Heliyon. 7: e07662. PMID 34401560 DOI: 10.1016/j.heliyon.2021.e07662   
2021 Ramos KA, James IE, Skobieranda F, Soergel DG, Ruff D, Fossler MJ. Two-Part Phase 1 Multiple-Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adults. Clinical Pharmacology in Drug Development. PMID 34480428 DOI: 10.1002/cpdd.1016   
2021 Yang Y, Liu Y, Song H, Li Y, Wang Q. Design, Synthesis, and Insecticidal Activity of Novel Triazone Derivatives Containing Sulfonamide or Sulfonimide Moieties. Journal of Agricultural and Food Chemistry. PMID 34375105 DOI: 10.1021/acs.jafc.1c01925   
2021 Ponnapakkam T, Bongay-Williams K, Beamon T, Hooks R, Cheatham D, Goyal N, Anbalagan M, Foroozesh M. Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer. Toxicology Reports. 8: 1521-1526. PMID 34401362 DOI: 10.1016/j.toxrep.2021.07.022   
2021 Garrido-Suárez BB, Garrido G, Bellma Menéndez A, Merino N, Valdés O, Delgado-Hernández R, Granados-Soto V. Synergistic interaction between amitriptyline and paracetamol in persistent and neuropathic pain models: An isobolografic analysis. Neurochemistry International. 150: 105160. PMID 34411687 DOI: 10.1016/j.neuint.2021.105160   
2021 Port A, Shaw JV, Klopp-Schulze L, Bytyqi A, Vetter C, Hussey E, Mammasse N, Ona V, Bachmann A, Strugala D, Reh C, Goteti K. Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll-like receptors 7 and 8. Pharmacology Research & Perspectives. 9: e00842. PMID 34414672 DOI: 10.1002/prp2.842   
2021 Techera Antunes FT, de Souza AH, Caminski ES, Greggio S, Venturin GT, da Costa JC, Taffarel M, Rebelo IN, Gomez MV, Correa DS, Vilanova FN, Regner AP, Dallegrave E. Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats. Neurotoxicology. PMID 34478769 DOI: 10.1016/j.neuro.2021.08.016   
2021 Fukaya Y, Kimura T, Yoshimura K, Umemura K, Kawamoto H. A Dose-Confirmation Phase 1 Study to Evaluate the Safety and Pharmacology of Glucarpidase in Healthy Volunteers. Clinical Pharmacology in Drug Development. PMID 34435467 DOI: 10.1002/cpdd.1010   
2021 López-Sanromán FJ, Freilich GM, Gomez-Cisneros D, Varela M, Santiago I, Manso-Díaz G. Accelerometric Evaluation of the Locomotor Pattern After Administration of Morphine in Conscious Healthy Horses. Journal of Equine Veterinary Science. 104: 103701. PMID 34416984 DOI: 10.1016/j.jevs.2021.103701   
2021 Sartini I, Łebkowska-Wieruszewska B, Lisowski A, Poapolathep A, Sitovs A, Giorgi M. Doxycycline pharmacokinetics in geese. Journal of Veterinary Pharmacology and Therapeutics. PMID 34318509 DOI: 10.1111/jvp.13002   
2021 Talley AK, Thurston A, Moore G, Gupta VK, Satterfield M, Manyak E, Stokes S, Dane A, Melnick D. First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections. Antimicrobial Agents and Chemotherapy. AAC0120821. PMID 34491803 DOI: 10.1128/AAC.01208-21   
2021 Takeuchi K, Kuroda Y, Numano T, Kimura M, Hayashi S, Furukawa S. Comparison of acute inhalation toxicity of sulfuric acid by the inhalation and intratracheal instillation methods. Journal of Toxicologic Pathology. 34: 269-273. PMID 34290483 DOI: 10.1293/tox.2020-0086   
2021 Cunneen A, Pratt S, Perkins N, McEwen M, Truchetti G, Rainger J, Farry T, Kidd L, Goodwin W. Total Intravenous Anaesthesia with Ketamine, Medetomidine and Midazolam as Part of a Balanced Anaesthesia Technique in Horses Undergoing Castration. Veterinary Sciences. 8. PMID 34437464 DOI: 10.3390/vetsci8080142   
2021 Li X, Gao L, Liu J, Zhang H, Chen H, Yang L, Wu M, Li C, Zhu X, Ding Y, Sun L. Safety, Tolerability and Pharmacokinetics of the Serotonin 5-HT6 Receptor Antagonist, HEC30654, in Healthy Chinese Subjects. Frontiers in Pharmacology. 12: 726536. PMID 34489712 DOI: 10.3389/fphar.2021.726536   
2021 Yan L, Gao F, Shi W, Geng B, Zhang J, Mao J, Tian Y, Ren L, Dai X, Chen J, Zhu J, Zhang X. A Two-Generation Reproductive Toxicity Study of Lanthanum Nitrate in SD Rats. Biological Trace Element Research. PMID 34347232 DOI: 10.1007/s12011-021-02841-9   
2021 Bruss J, Lister T, Gupta VK, Stone E, Morelli L, Lei Y, Melnick D. Single- and Multiple-Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative, SPR206. Antimicrobial Agents and Chemotherapy. AAC0073921. PMID 34339267 DOI: 10.1128/AAC.00739-21   
2021 Matthews RP, Ankrom W, Friedman E, Jackson Rudd D, Liu Y, Mogg R, Panebianco D, De Lepeleire I, Petkova M, Grobler JA, Stoch SA, Iwamoto M. Safety, tolerability, and pharmacokinetics of single- and multiple-dose administration of islatravir (MK-8591) in adults without HIV. Clinical and Translational Science. PMID 34463432 DOI: 10.1111/cts.13048   
2021 Tournade CM, Fink DM, Williams SR, Mans C. Effects of Tinidazole on Food Intake in Chinchillas (Chinchilla lanigera). Journal of the American Association For Laboratory Animal Science : Jaalas. PMID 34325772 DOI: 10.30802/AALAS-JAALAS-20-000141   
2021 , Bampidis V, Azimonti G, Bastos ML, Christensen H, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, et al. Safety and efficacy of a feed additive consisting of a flavonoid-rich dried extract of  ×  L. fruit (bitter orange extract) for use in all animal species (FEFANA asbl). Efsa Journal. European Food Safety Authority. 19: e06709. PMID 34335921 DOI: 10.2903/j.efsa.2021.6709   
2021 McDonough JH, McMonagle JD, Capacio BR. Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys. Drug and Chemical Toxicology. 1-8. PMID 34251950 DOI: 10.1080/01480545.2021.1916171   
2021 Zhang J, Ma L, Wan X, Shan J, Qu Y, Hashimoto K. (R)-Ketamine attenuates LPS-induced endotoxin-derived delirium through inhibition of neuroinflammation. Psychopharmacology. PMID 34313805 DOI: 10.1007/s00213-021-05889-6   
2021 Janikova M, Mainerova K, Vojtechova I, Petrasek T, Svoboda J, Stuchlik A. Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task. Biomolecules. 11. PMID 34356631 DOI: 10.3390/biom11071007   
2021 Boness HVM, de Oliveira MS, Batista CSC, Almeida LS, Boffo EF, Villarreal CF, Cruz FG. Anti-Inflammatory and Antinociceptive Properties of Kielmeyerone A, a Chromenone Isolated from the Roots of . Journal of Natural Products. PMID 34283606 DOI: 10.1021/acs.jnatprod.1c00157   
2021 Huang YY, Deng J, Tian YJ, Liang J, Xie X, Huang Y, Zhu J, Zhu Z, Zhou Q, He X, Luo HB. Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. Journal of Medicinal Chemistry. PMID 34520193 DOI: 10.1021/acs.jmedchem.1c01085   
2021 Mahmoud YK, Ali AA, Abdelrazek HMA, Aldayel TS, Abdel-Daim MM, El-Menyawy MAI. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology. 10. PMID 34356537 DOI: 10.3390/biology10070682   
2021 Galluppi GR, Polhamus DG, Fisher JM, Hopkins SC, Koblan KS. Population Pharmacokinetic Analysis of Ulotaront in Subjects with Schizophrenia. Cpt: Pharmacometrics & Systems Pharmacology. PMID 34292664 DOI: 10.1002/psp4.12692   
2021 Galluppi GR, Polhamus DG, Fisher JM, Hopkins SC, Koblan KS. Population Pharmacokinetic Analysis of Ulotaront in Subjects with Schizophrenia. Cpt: Pharmacometrics & Systems Pharmacology. PMID 34292664 DOI: 10.1002/psp4.12692   
2021 Park SH, Lim JO, Kim WI, Park SW, Lee SJ, Shin IS, Moon C, Kim JH, Heo JD, Kim JC. Subchronic Toxicity Evaluation of Aluminum Oxide Nanoparticles in Rats Following 28-Day Repeated Oral Administration. Biological Trace Element Research. PMID 34535882 DOI: 10.1007/s12011-021-02926-5   
2021 Chesler KC, Motz CT, Bales KL, Allen RA, Vo HK, Pardue MT. Voluntary oral dosing for precise experimental compound delivery in adult rats. Laboratory Animals. 236772211016926. PMID 34392713 DOI: 10.1177/00236772211016926   
2021 Troni E, Beccari G, D'Amato R, Tini F, Baldo D, Senatore MT, Beone GM, Fontanella MC, Prodi A, Businelli D, Covarelli L. In Vitro Evaluation of the Inhibitory Activity of Different Selenium Chemical Forms on the Growth of a Strain Isolated from Rice Seedlings. Plants (Basel, Switzerland). 10. PMID 34451770 DOI: 10.3390/plants10081725   
2021 Bello IJ, Oyebode OT, Olanlokun JO, Omodara TO, Olorunsogo OO. Plumbagin induces testicular damage via mitochondrial-dependent cell death. Chemico-Biological Interactions. 109582. PMID 34302802 DOI: 10.1016/j.cbi.2021.109582   
2021 Salman T, Afroz R, Nawaz S, Mahmood K, Haleem DJ, Zarina S. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie. 191: 51-61. PMID 34454977 DOI: 10.1016/j.biochi.2021.08.009