Stanley Watson - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
molecular neruobiology

365 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Mamdani F, Weber MD, Bunney B, Burke K, Cartagena P, Walsh D, Lee FS, Barchas J, Schatzberg AF, Myers RM, Watson SJ, Akil H, Vawter MP, Bunney WE, Sequeira A. Identification of potential blood biomarkers associated with suicide in major depressive disorder. Translational Psychiatry. 12: 159. PMID 35422091 DOI: 10.1038/s41398-022-01918-w  0.511
2022 Singh T, Poterba T, Curtis D, Akil H, Al Eissa M, Barchas JD, Bass N, Bigdeli TB, Breen G, Bromet EJ, Buckley PF, Bunney WE, Bybjerg-Grauholm J, Byerley WF, Chapman SB, ... ... Watson SJ, et al. Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature. PMID 35396579 DOI: 10.1038/s41586-022-04556-w  0.502
2022 Maras PM, Hebda-Bauer EK, Hagenauer MH, Hilde KL, Blandino P, Watson SJ, Akil H. Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. Translational Psychiatry. 12: 105. PMID 35292624 DOI: 10.1038/s41398-022-01821-4  0.541
2022 Murra D, Hilde KL, Fitzpatrick A, Maras PM, Watson SJ, Akil H. Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress. Neurobiology of Stress. 17: 100437. PMID 35242893 DOI: 10.1016/j.ynstr.2022.100437  0.498
2021 Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, ... ... Watson S, et al. Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry. PMID 33674754 DOI: 10.1038/s41380-021-01063-8  0.482
2021 Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, ... ... Watson S, et al. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry. PMID 33483695 DOI: 10.1038/s41380-020-01006-9  0.498
2021 Kumar V, Krolewski DM, Hebda-Bauer EK, Parsegian A, Martin B, Foltz M, Akil H, Watson SJ. Optimization and evaluation of fluorescence in situ hybridization chain reaction in cleared fresh-frozen brain tissues. Brain Structure & Function. PMID 33386994 DOI: 10.1007/s00429-020-02194-4  0.529
2020 Birt IA, Hagenauer MH, Clinton SM, Aydin C, Blandino P, Stead JDH, Hilde KL, Meng F, Thompson RC, Khalil H, Stefanov A, Maras P, Zhou Z, Hebda-Bauer EK, Goldman D, ... Watson SJ, et al. Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model. Biological Psychiatry. PMID 32762937 DOI: 10.1016/J.Biopsych.2020.05.024  0.546
2020 Spencer-Segal JL, Singer BH, Laborc K, Somayaji K, Watson SJ, Standiford TJ, Akil H. Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction. Psychoneuroendocrinology. 117: 104679. PMID 32353815 DOI: 10.1016/j.psyneuen.2020.104679  0.542
2019 Ballaz SJ, Bourin M, Akil H, Watson SJ. Blockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109761. PMID 31526831 DOI: 10.1016/j.pnpbp.2019.109761  0.558
2019 Limon A, Delbruck E, Yassine A, Pandya D, Myers RM, Barchas JD, Lee F, Schatzberg, Watson SJ, Akil H, Bunney WE, Vawter MP, Sequeira A. Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA receptors. Translational Psychiatry. 9: 218. PMID 31488811 DOI: 10.1038/S41398-019-0551-1  0.63
2019 Hebda-Bauer EK, Dokas LA, Watson SJ, Akil H. Adaptation to single housing is dynamic: Changes in hormone levels, gene expression, signaling in the brain, and anxiety-like behavior in adult male C57Bl/6J mice. Hormones and Behavior. PMID 31220462 DOI: 10.1016/j.yhbeh.2019.06.005  0.558
2019 Zhou Z, Blandino P, Yuan Q, Shen PH, Hodgkinson CA, Virkkunen M, Watson SJ, Akil H, Goldman D. Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182603 DOI: 10.1073/Pnas.1820410116  0.548
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Watson SJ, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.614
2019 Langenecker SA, Mickey BJ, Eichhammer P, Sen S, Elverman KH, Kennedy SE, Heitzeg MM, Ribeiro SM, Love TM, Hsu DT, Koeppe RA, Watson SJ, Akil H, Goldman D, Burmeister M, et al. Cognitive Control as a 5-HT-Based Domain That Is Disrupted in Major Depressive Disorder. Frontiers in Psychology. 10: 691. PMID 30984083 DOI: 10.3389/Fpsyg.2019.00691  0.485
2019 Turner CA, Hagenauer MH, Aurbach EL, Maras PM, Fournier CL, Blandino P, Chauhan RB, Panksepp J, Watson SJ, Akil H. Effects of early-life FGF2 on ultrasonic vocalizations (USVs) and the mu-opioid receptor in male Sprague-Dawley rats selectively-bred for differences in their response to novelty. Brain Research. PMID 30880118 DOI: 10.1016/J.Brainres.2019.03.011  0.6
2019 Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, et al. Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders. Nucleic Acids Research. PMID 30869147 DOI: 10.1093/Nar/Gkz164  0.625
2018 Wei Q, Krolewski DM, Moore S, Kumar V, Li F, Martin B, Tomer R, Murphy GG, Deisseroth K, Watson SJ, Akil H. Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224492 DOI: 10.1073/Pnas.1802237115  0.524
2018 Hagenauer MH, Schulmann A, Li JZ, Vawter MP, Walsh DM, Thompson RC, Turner CA, Bunney WE, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H. Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis. Plos One. 13: e0200003. PMID 30016334 DOI: 10.1371/Journal.Pone.0200003  0.648
2018 Turner CA, Sharma V, Hagenauer MH, Chaudhury S, O'Connor AM, Hebda-Bauer EK, Thompson RC, Myers RM, Bunney WE, Barchas JD, Lee FS, Schatzberg AF, Watson SJ, Akil H. Connective Tissue Growth Factor Is a Novel Prodepressant. Biological Psychiatry. PMID 29861095 DOI: 10.1016/J.Biopsych.2018.04.013  0.613
2018 Turner CA, Lyons DM, Buckmaster CL, Aurbach EL, Watson SJ, Schatzberg AF, Akil H. Neural cell adhesion molecule peptide mimetics modulate emotionality: pharmacokinetic and behavioral studies in rats and non-human primates. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29703997 DOI: 10.1038/S41386-018-0052-6  0.575
2018 Rollins BL, Morgan L, Hjelm BE, Sequeira A, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP. Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence. Molecular Neuropsychiatry. 3: 157-169. PMID 29594135 DOI: 10.1159/000484348  0.61
2017 Krolewski DM, Kumar V, Martin B, Tomer R, Deisseroth K, Myers RM, Schatzberg AF, Lee FS, Barchas JD, Bunney WE, Akil H, Watson SJ. Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations. Brain Structure & Function. PMID 29243106 DOI: 10.1007/S00429-017-1583-Z  0.599
2017 Gupta S, M-Redmond T, Meng F, Tidball A, Akil H, Watson S, Parent JM, Uhler M. Fibroblast Growth Factor 2 Regulates Activity and Gene Expression of Human Postmitotic Excitatory Neurons. Journal of Neurochemistry. PMID 29168882 DOI: 10.1111/Jnc.14255  0.602
2017 Lee AG, Hagenauer M, Absher D, Morrison KE, Bale TL, Myers RM, Watson SJ, Akil H, Schatzberg AF, Lyons DM. Stress amplifies sex differences in primate prefrontal profiles of gene expression. Biology of Sex Differences. 8: 36. PMID 29096718 DOI: 10.1186/S13293-017-0157-3  0.531
2017 Turner CA, Flagel SB, Blandino P, Watson SJ, Akil H. Utilizing a unique animal model to better understand human temperament. Current Opinion in Behavioral Sciences. 14: 108-114. PMID 28966969 DOI: 10.1016/J.Cobeha.2017.02.002  0.524
2017 Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, et al. Post-mortem molecular profiling of three psychiatric disorders. Genome Medicine. 9: 72. PMID 28754123 DOI: 10.1186/S13073-017-0458-5  0.613
2017 García-Fuster MJ, Parsegian A, Watson SJ, Akil H, Flagel SB. Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats. Psychopharmacology. PMID 28210781 DOI: 10.1007/s00213-017-4566-0  0.534
2017 Prater KE, Aurbach EL, Larcinese HK, Smith TN, Turner CA, Blandino P, Watson SJ, Maren S, Akil H. Selectively Bred Rats Provide a Unique Model of Vulnerability to PTSD-Like Behavior and Respond Differentially to FGF2 Augmentation Early in Life. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28205604 DOI: 10.1038/Npp.2017.37  0.552
2017 Akil H, Maras P, Hagenauer M, Aydin C, Brit I, Turner C, Watson S. 23. A Genetic and Developmental Model of Temperament in the Rat: Role of Neuroplasticity and Relevance to Human Mood Disorders Biological Psychiatry. 81: S10. DOI: 10.1016/J.Biopsych.2017.02.034  0.569
2016 Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA. Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. Translational Psychiatry. 6: e969. PMID 27922633 DOI: 10.1038/tp.2015.164  0.639
2016 Litvin Y, Turner CA, Rios MB, Maras PM, Chaudhury S, Baker MR, Blandino P, Watson SJ, Akil H, McEwen B. Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups. Hormones and Behavior. 86: 64-70. PMID 27693608 DOI: 10.1016/J.Yhbeh.2016.09.009  0.56
2016 Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. Microarrays (Basel, Switzerland). 5. PMID 27600072 DOI: 10.3390/microarrays5010006  0.644
2016 Turner CA, Watson SJ, Akil H. Fibroblast Growth Factor 2 Sits at the Interface of Stress and Anxiety. Biological Psychiatry. 80: 419-21. PMID 27565541 DOI: 10.1016/J.Biopsych.2016.07.010  0.479
2016 Azevedo JA, Carter BS, Meng F, Turner DL, Dai M, Schatzberg AF, Barchas JD, Jones EG, Bunney WE, Myers RM, Akil H, Watson SJ, Thompson RC. The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression. Journal of Psychiatric Research. 82: 58-67. PMID 27468165 DOI: 10.1016/J.Jpsychires.2016.07.012  0.602
2016 Flagel SB, Chaudhury S, Waselus M, Kelly R, Sewani S, Clinton SM, Thompson RC, Watson SJ, Akil H. Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114539 DOI: 10.1073/Pnas.1520491113  0.794
2016 Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. Microarrays (Basel, Switzerland). 5. PMID 26998349 DOI: 10.3390/Microarrays5010006  0.644
2015 Medina A, Watson SJ, Bunney W, Myers RM, Schatzberg A, Barchas J, Akil H, Thompson RC. Evidence for alterations of the glial syncytial function in major depressive disorder. Journal of Psychiatric Research. 72: 15-21. PMID 26519765 DOI: 10.1016/J.Jpsychires.2015.10.010  0.618
2015 Rana S, Nam H, Glover ME, Akil H, Watson SJ, Clinton SM, Kerman IA. Protective Effects of Chronic Mild Stress during Adolescence in the Low Novelty Responder Rat. Stress (Amsterdam, Netherlands). 1-18. PMID 26473581 DOI: 10.3109/10253890.2015.1108304  0.736
2015 Turner CA, Eren-Koçak E, Inui EG, Watson SJ, Akil H. Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disorders. Seminars in Cell & Developmental Biology. PMID 26454097 DOI: 10.1016/J.Semcdb.2015.10.003  0.525
2015 Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA. Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder. Translational Psychiatry. 5: e636. PMID 26371764 DOI: 10.1038/Tp.2015.134  0.66
2015 Aurbach EL, Inui EG, Turner CA, Hagenauer MH, Prater KE, Li JZ, Absher D, Shah N, Blandino P, Bunney WE, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H. Fibroblast growth factor 9 is a novel modulator of negative affect. Proceedings of the National Academy of Sciences of the United States of America. 112: 11953-8. PMID 26351673 DOI: 10.1073/Pnas.1510456112  0.673
2015 Sequeira A, Rollins B, Magnan C, van Oven M, Baldi P, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Vawter MP. Mitochondrial mutations in subjects with psychiatric disorders. Plos One. 10: e0127280. PMID 26011537 DOI: 10.1371/Journal.Pone.0127280  0.626
2015 Robinson MJ, Burghardt PR, Patterson CM, Nobile CW, Akil H, Watson SJ, Berridge KC, Ferrario CR. Individual Differences in Cue-Induced Motivation and Striatal Systems in Rats Susceptible to Diet-Induced Obesity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2113-23. PMID 25761571 DOI: 10.1038/Npp.2015.71  0.495
2015 Bunney BG, Li JZ, Walsh DM, Stein R, Vawter MP, Cartagena P, Barchas JD, Schatzberg AF, Myers RM, Watson SJ, Akil H, Bunney WE. Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder. Molecular Psychiatry. 20: 48-55. PMID 25349171 DOI: 10.1038/Mp.2014.138  0.657
2014 Chaudhury S, Aurbach EL, Sharma V, Blandino P, Turner CA, Watson SJ, Akil H. FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: partnership with H3K9me3. Proceedings of the National Academy of Sciences of the United States of America. 111: 11834-9. PMID 25071177 DOI: 10.1073/Pnas.1411618111  0.56
2014 Turner CA, Thompson RC, Bunney WE, Schatzberg AF, Barchas JD, Myers RM, Akil H, Watson SJ. Altered choroid plexus gene expression in major depressive disorder. Frontiers in Human Neuroscience. 8: 238. PMID 24795602 DOI: 10.3389/Fnhum.2014.00238  0.659
2014 Hamilton DE, Cooke CL, Carter BS, Akil H, Watson SJ, Thompson RC. Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype. Physiological Genomics. 46: 290-301. PMID 24569673 DOI: 10.1152/physiolgenomics.00152.2013  0.526
2014 Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ, Akil H, Bunney WE, Delisi LE, Byerley W, Vawter MP. Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex. Schizophrenia Research. 152: 111-6. PMID 24315717 DOI: 10.1016/J.Schres.2013.11.021  0.479
2014 Clinton SM, Watson SJ, Akil H. High novelty-seeking rats are resilient to negative physiological effects of the early life stress. Stress (Amsterdam, Netherlands). 17: 97-107. PMID 24090131 DOI: 10.3109/10253890.2013.850670  0.53
2014 Flagel SB, Waselus M, Clinton SM, Watson SJ, Akil H. Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty. Neuropharmacology. 76: 425-36. PMID 23639434 DOI: 10.1016/J.Neuropharm.2013.04.033  0.795
2013 Tomita H, Ziegler ME, Kim HB, Evans SJ, Choudary PV, Li JZ, Meng F, Dai M, Myers RM, Neal CR, Speed TP, Barchas JD, Schatzberg AF, Watson SJ, Akil H, et al. G protein-linked signaling pathways in bipolar and major depressive disorders. Frontiers in Genetics. 4: 297. PMID 24391664 DOI: 10.3389/Fgene.2013.00297  0.653
2013 Ballaz SJ, Perez J, Waselus M, Akil H, Watson SJ. Interaction between cholecystokinin and the fibroblast growth factor system in the ventral tegmental area of selectively bred high- and low-responder rats. Neuroscience. 255: 68-75. PMID 24121132 DOI: 10.1016/J.Neuroscience.2013.09.063  0.801
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Watson SJ, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.608
2013 Waselus M, Flagel SB, Jedynak JP, Akil H, Robinson TE, Watson SJ. Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats. Neuroscience. 248: 571-84. PMID 23811073 DOI: 10.1016/J.Neuroscience.2013.06.042  0.779
2013 Perez-Sepulveda JA, Flagel SB, Garcia-Fuster MJ, Slusky RJ, Aldridge JW, Watson S, Akil H. Differential impact of a complex environment on positive affect in an animal model of individual differences in emotionality. Neuroscience. 248: 436-47. PMID 23806722 DOI: 10.1016/j.neuroscience.2013.06.015  0.605
2013 Guella I, Sequeira A, Rollins B, Morgan L, Torri F, van Erp TG, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Potkin SG, Macciardi F, Vawter MP. Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. Journal of Psychiatric Research. 47: 1215-21. PMID 23786914 DOI: 10.1016/J.Jpsychires.2013.05.021  0.61
2013 Medina A, Burke S, Thompson RC, Bunney W, Myers RM, Schatzberg A, Akil H, Watson SJ. Glutamate transporters: a key piece in the glutamate puzzle of major depressive disorder. Journal of Psychiatric Research. 47: 1150-6. PMID 23706640 DOI: 10.1016/J.Jpsychires.2013.04.007  0.52
2013 Li JZ, Bunney BG, Meng F, Hagenauer MH, Walsh DM, Vawter MP, Evans SJ, Choudary PV, Cartagena P, Barchas JD, Schatzberg AF, Jones EG, Myers RM, Watson SJ, Akil H, et al. Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. Proceedings of the National Academy of Sciences of the United States of America. 110: 9950-5. PMID 23671070 DOI: 10.1073/Pnas.1305814110  0.663
2013 Medina A, Seasholtz AF, Sharma V, Burke S, Bunney W, Myers RM, Schatzberg A, Akil H, Watson SJ. Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder. Journal of Psychiatric Research. 47: 307-14. PMID 23219281 DOI: 10.1016/J.Jpsychires.2012.11.002  0.569
2013 Hebda-Bauer EK, Simmons TA, Sugg A, Ural E, Stewart JA, Beals JL, Wei Q, Watson SJ, Akil H. 3xTg-AD mice exhibit an activated central stress axis during early-stage pathology. Journal of Alzheimer's Disease : Jad. 33: 407-22. PMID 22976078 DOI: 10.3233/JAD-2012-121438  0.541
2012 Kerman IA, Bernard R, Bunney WE, Jones EG, Schatzberg AF, Myers RM, Barchas JD, Akil H, Watson SJ, Thompson RC. Evidence for transcriptional factor dysregulation in the dorsal raphe nucleus of patients with major depressive disorder. Frontiers in Neuroscience. 6: 135. PMID 23087602 DOI: 10.3389/Fnins.2012.00135  0.791
2012 Turner CA, Watson SJ, Akil H. The fibroblast growth factor family: neuromodulation of affective behavior. Neuron. 76: 160-74. PMID 23040813 DOI: 10.1016/J.Neuron.2012.08.037  0.539
2012 García-Fuster MJ, Flagel SB, Mahmood ST, Watson SJ, Akil H. Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus. Plos One. 7: e42092. PMID 22860061 DOI: 10.1371/journal.pone.0042092  0.561
2012 Turner CA, Watson SJ, Akil H. Fibroblast growth factor-2: an endogenous antidepressant and anxiolytic molecule? Biological Psychiatry. 72: 254-5. PMID 22840947 DOI: 10.1016/J.Biopsych.2012.05.025  0.573
2012 Clinton SM, Turner CA, Flagel SB, Simpson DN, Watson SJ, Akil H. Neonatal fibroblast growth factor treatment enhances cocaine sensitization. Pharmacology, Biochemistry, and Behavior. 103: 6-17. PMID 22819969 DOI: 10.1016/J.Pbb.2012.07.006  0.544
2012 Sequeira A, Morgan L, Walsh DM, Cartagena PM, Choudary P, Li J, Schatzberg AF, Watson SJ, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP. Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide. Plos One. 7: e35367. PMID 22558144 DOI: 10.1371/Journal.Pone.0035367  0.539
2012 García-Fuster MJ, Parks GS, Clinton SM, Watson SJ, Akil H, Civelli O. The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 607-13. PMID 22209364 DOI: 10.1016/J.Euroneuro.2011.12.001  0.565
2012 Capriles N, Watson S, Akil H. Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats. Psychopharmacology. 220: 731-40. PMID 21989806 DOI: 10.1007/s00213-011-2524-9  0.58
2012 Wei Q, Fentress HM, Hoversten MT, Zhang L, Hebda-Bauer EK, Watson SJ, Seasholtz AF, Akil H. Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization. Biological Psychiatry. 71: 224-31. PMID 21872848 DOI: 10.1016/J.Biopsych.2011.07.009  0.577
2012 Kerman IA, Clinton SM, Simpson DN, Bedrosian TA, Bernard R, Akil H, Watson SJ. Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms. Psychoneuroendocrinology. 37: 256-69. PMID 21775066 DOI: 10.1016/j.psyneuen.2011.06.010  0.761
2011 Clinton SM, Kerman IA, Orr HR, Bedrosian TA, Abraham AD, Simpson DN, Watson SJ, Akil H. Pattern of forebrain activation in high novelty-seeking rats following aggressive encounter. Brain Research. 1422: 20-31. PMID 21974861 DOI: 10.1016/j.brainres.2011.08.033  0.767
2011 Flagel SB, Cameron CM, Pickup KN, Watson SJ, Akil H, Robinson TE. A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions. Neuroscience. 196: 80-96. PMID 21945724 DOI: 10.1016/J.Neuroscience.2011.09.004  0.639
2011 Kerman IA, Clinton SM, Bedrosian TA, Abraham AD, Rosenthal DT, Akil H, Watson SJ. High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups. Brain Research. 1419: 34-45. PMID 21925645 DOI: 10.1016/J.Brainres.2011.08.038  0.762
2011 Clinton SM, Stead JD, Miller S, Watson SJ, Akil H. Developmental underpinnings of differences in rodent novelty-seeking and emotional reactivity. The European Journal of Neuroscience. 34: 994-1005. PMID 21864320 DOI: 10.1111/j.1460-9568.2011.07811.x  0.575
2011 García-Fuster MJ, Flagel SB, Mahmood ST, Mayo LM, Thompson RC, Watson SJ, Akil H. Decreased proliferation of adult hippocampal stem cells during cocaine withdrawal: possible role of the cell fate regulator FADD. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2303-17. PMID 21796105 DOI: 10.1038/npp.2011.119  0.525
2011 Moon E, Rollins B, Mesén A, Sequeira A, Myers RM, Akil H, Watson SJ, Barchas J, Jones EG, Schatzberg A, Bunney WE, DeLisi LE, Byerley W, Vawter MP. Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population. Schizophrenia Research. 131: 52-7. PMID 21745728 DOI: 10.1016/J.Schres.2011.06.024  0.623
2011 Turner CA, Clinton SM, Thompson RC, Watson SJ, Akil H. Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals. Proceedings of the National Academy of Sciences of the United States of America. 108: 8021-5. PMID 21518861 DOI: 10.1073/Pnas.1103732108  0.569
2011 Calvo N, Cecchi M, Kabbaj M, Watson SJ, Akil H. Differential effects of social defeat in rats with high and low locomotor response to novelty. Neuroscience. 183: 81-9. PMID 21453756 DOI: 10.1016/J.Neuroscience.2011.03.046  0.55
2011 Stedenfeld KA, Clinton SM, Kerman IA, Akil H, Watson SJ, Sved AF. Novelty-seeking behavior predicts vulnerability in a rodent model of depression. Physiology & Behavior. 103: 210-6. PMID 21303678 DOI: 10.1016/j.physbeh.2011.02.001  0.751
2011 Eren-Koçak E, Turner CA, Watson SJ, Akil H. Short-hairpin RNA silencing of endogenous fibroblast growth factor 2 in rat hippocampus increases anxiety behavior. Biological Psychiatry. 69: 534-40. PMID 21215386 DOI: 10.1016/J.Biopsych.2010.11.020  0.556
2011 Burghardt PR, Flagel SB, Burghardt KJ, Britton SL, Gerard-Koch L, Watson SJ, Akil H. Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 390-401. PMID 20927049 DOI: 10.1038/npp.2010.144  0.545
2011 Bernard R, Kerman IA, Thompson RC, Jones EG, Bunney WE, Barchas JD, Schatzberg AF, Myers RM, Akil H, Watson SJ. Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression. Molecular Psychiatry. 16: 634-46. PMID 20386568 DOI: 10.1038/Mp.2010.44  0.79
2011 García-Fuster M, Parks G, Clinton S, Watson S, Akil H, Civelli O. P.2.b.009 The melanin-concentrating hormone system and emotional-like behaviour European Neuropsychopharmacology. 21: S372-S373. DOI: 10.1016/S0924-977X(11)70597-1  0.462
2010 Krolewski DM, Medina A, Kerman IA, Bernard R, Burke S, Thompson RC, Bunney WE, Schatzberg AF, Myers RM, Akil H, Jones EG, Watson SJ. Expression patterns of corticotropin-releasing factor, arginine vasopressin, histidine decarboxylase, melanin-concentrating hormone, and orexin genes in the human hypothalamus. The Journal of Comparative Neurology. 518: 4591-611. PMID 20886624 DOI: 10.1002/Cne.22480  0.764
2010 Clinton SM, Bedrosian TA, Abraham AD, Watson SJ, Akil H. Neural and environmental factors impacting maternal behavior differences in high- versus low-novelty-seeking rats. Hormones and Behavior. 57: 463-73. PMID 20156440 DOI: 10.1016/j.yhbeh.2010.02.004  0.54
2010 García-Fuster MJ, Perez JA, Clinton SM, Watson SJ, Akil H. Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse. The European Journal of Neuroscience. 31: 79-89. PMID 20104651 DOI: 10.1111/j.1460-9568.2009.07045.x  0.522
2010 Flagel SB, Robinson TE, Clark JJ, Clinton SM, Watson SJ, Seeman P, Phillips PE, Akil H. An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 388-400. PMID 19794408 DOI: 10.1038/npp.2009.142  0.65
2009 Akil H, Watson SJ, Dalack GW, Greden JF, Zubieta JK. In memory of Elizabeth Young. Biological Psychiatry. 66: e25-6. PMID 19900609 DOI: 10.1016/j.biopsych.2009.09.018  0.435
2009 Martin MV, Rollins B, Sequeira PA, Mesén A, Byerley W, Stein R, Moon EA, Akil H, Jones EG, Watson SJ, Barchas J, DeLisi LE, Myers RM, Schatzberg A, Bunney WE, et al. Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation. Bmc Medical Genomics. 2: 62. PMID 19772658 DOI: 10.1186/1755-8794-2-62  0.608
2009 Evans SJ, Akil H, Watson SJ. Analyzing gene expression in depression. The American Journal of Psychiatry. 166: 961-3. PMID 19723790 DOI: 10.1176/appi.ajp.2009.09060806  0.513
2009 Perez JA, Clinton SM, Turner CA, Watson SJ, Akil H. A new role for FGF2 as an endogenous inhibitor of anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6379-87. PMID 19439615 DOI: 10.1523/Jneurosci.4829-08.2009  0.554
2009 Scott LJ, Muglia P, Kong XQ, Guan W, Flickinger M, Upmanyu R, Tozzi F, Li JZ, Burmeister M, Absher D, Thompson RC, Francks C, Meng F, Antoniades A, Southwick AM, ... ... Watson SJ, et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America. 106: 7501-6. PMID 19416921 DOI: 10.1073/Pnas.0813386106  0.6
2009 Rollins B, Martin MV, Sequeira PA, Moon EA, Morgan LZ, Watson SJ, Schatzberg A, Akil H, Myers RM, Jones EG, Wallace DC, Bunney WE, Vawter MP. Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder. Plos One. 4: e4913. PMID 19290059 DOI: 10.1371/Journal.Pone.0004913  0.494
2009 Sonmez K, Zaveri NT, Kerman IA, Burke S, Neal CR, Xie X, Watson SJ, Toll L. Evolutionary sequence modeling for discovery of peptide hormones. Plos Computational Biology. 5: e1000258. PMID 19132080 DOI: 10.1371/Journal.Pcbi.1000258  0.637
2009 Bernard R, Kerman IA, Meng F, Evans SJ, Amrein I, Jones EG, Bunney WE, Akil H, Watson SJ, Thompson RC. Gene expression profiling of neurochemically defined regions of the human brain by in situ hybridization-guided laser capture microdissection. Journal of Neuroscience Methods. 178: 46-54. PMID 19070632 DOI: 10.1016/J.Jneumeth.2008.11.012  0.749
2009 Turner CA, Capriles N, Flagel SB, Perez JA, Clinton SM, Watson SJ, Akil H. Neonatal FGF2 alters cocaine self-administration in the adult rat. Pharmacology, Biochemistry, and Behavior. 92: 100-4. PMID 19014962 DOI: 10.1016/J.Pbb.2008.10.018  0.543
2009 García-Fuster MJ, Clinton SM, Watson SJ, Akil H. Effect of cocaine on Fas-associated protein with death domain in the rat brain: individual differences in a model of differential vulnerability to drug abuse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1123-34. PMID 18580876 DOI: 10.1038/npp.2008.88  0.538
2008 Turner CA, Flagel SB, Clinton SM, Akil H, Watson SJ. Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat. Neuroscience Letters. 446: 105-7. PMID 18824081 DOI: 10.1016/J.Neulet.2008.09.037  0.571
2008 Cecchi M, Capriles N, Watson SJ, Akil H. Differential responses to morphine-induced analgesia in the tail-flick test. Behavioural Brain Research. 194: 146-51. PMID 18656501 DOI: 10.1016/J.Bbr.2008.06.034  0.545
2008 Turner CA, Gula EL, Taylor LP, Watson SJ, Akil H. Antidepressant-like effects of intracerebroventricular FGF2 in rats. Brain Research. 1224: 63-8. PMID 18586016 DOI: 10.1016/J.Brainres.2008.05.088  0.784
2008 Day HE, Kryskow EM, Watson SJ, Akil H, Campeau S. Regulation of hippocampal alpha1d adrenergic receptor mRNA by corticosterone in adrenalectomized rats. Brain Research. 1218: 132-40. PMID 18534559 DOI: 10.1016/J.Brainres.2008.04.067  0.577
2008 Akil H, Evans SJ, Turner CA, Perez J, Myers RM, Bunney WE, Jones EG, Watson SJ. The fibroblast growth factor family and mood disorders. Novartis Foundation Symposium. 289: 94-6; discussion 97-. PMID 18497097 DOI: 10.1002/9780470751251.Ch8  0.496
2008 Jama A, Cecchi M, Calvo N, Watson SJ, Akil H. Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test. Psychopharmacology. 198: 333-40. PMID 18438645 DOI: 10.1007/s00213-008-1126-7  0.56
2008 Shao L, Martin MV, Watson SJ, Schatzberg A, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP. Mitochondrial involvement in psychiatric disorders. Annals of Medicine. 40: 281-95. PMID 18428021 DOI: 10.1080/07853890801923753  0.509
2008 Ballaz SJ, Akil H, Watson SJ. The CCK-system underpins novelty-seeking behavior in the rat: gene expression and pharmacological analyses. Neuropeptides. 42: 245-53. PMID 18410964 DOI: 10.1016/j.npep.2008.03.001  0.586
2008 Sequeira A, Meng F, Rollins B, Myers RM, Jones EG, Watson SJ, Akil H, Schatzberg AF, Barchas J, Bunney WE, Vawter MP. Coding SNPs included in exon arrays for the study of psychiatric disorders. Molecular Psychiatry. 13: 363-5. PMID 18347597 DOI: 10.1038/Sj.Mp.4002123  0.646
2008 Briand LA, Flagel SB, Garcia-Fuster MJ, Watson SJ, Akil H, Sarter M, Robinson TE. Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2969-80. PMID 18305460 DOI: 10.1038/npp.2008.18  0.633
2008 Clinton S, Miller S, Watson SJ, Akil H. Prenatal stress does not alter innate novelty-seeking behavioral traits, but differentially affects individual differences in neuroendocrine stress responsivity. Psychoneuroendocrinology. 33: 162-77. PMID 18077099 DOI: 10.1016/j.psyneuen.2007.10.012  0.536
2008 Turner CA, Calvo N, Frost DO, Akil H, Watson SJ. The fibroblast growth factor system is downregulated following social defeat. Neuroscience Letters. 430: 147-50. PMID 18061349 DOI: 10.1016/J.Neulet.2007.10.041  0.546
2008 Flagel SB, Watson SJ, Akil H, Robinson TE. Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization. Behavioural Brain Research. 186: 48-56. PMID 17719099 DOI: 10.1016/j.bbr.2007.07.022  0.625
2007 Hebda-Bauer EK, Luo J, Watson SJ, Akil H. Female CREBalphadelta- deficient mice show earlier age-related cognitive deficits than males. Neuroscience. 150: 260-72. PMID 18029102 DOI: 10.1016/j.neuroscience.2007.09.019  0.459
2007 Ballaz SJ, Akil H, Watson SJ. The CCK-system mediates adaptation to novelty-induced stress in the rat: a pharmacological evidence. Neuroscience Letters. 428: 27-32. PMID 17950531 DOI: 10.1016/j.neulet.2007.09.035  0.568
2007 Kerman IA, Bernard R, Rosenthal D, Beals J, Akil H, Watson SJ. Distinct populations of presympathetic-premotor neurons express orexin or melanin-concentrating hormone in the rat lateral hypothalamus. The Journal of Comparative Neurology. 505: 586-601. PMID 17924541 DOI: 10.1002/Cne.21511  0.758
2007 Ballaz SJ, Akil H, Watson SJ. Previous experience affects subsequent anxiety-like responses in rats bred for novelty seeking. Behavioral Neuroscience. 121: 1113-8. PMID 17907843 DOI: 10.1037/0735-7044.121.5.1113  0.542
2007 Karssen AM, Her S, Li JZ, Patel PD, Meng F, Bunney WE, Jones EG, Watson SJ, Akil H, Myers RM, Schatzberg AF, Lyons DM. Stress-induced changes in primate prefrontal profiles of gene expression. Molecular Psychiatry. 12: 1089-102. PMID 17893703 DOI: 10.1038/Sj.Mp.4002095  0.548
2007 Li JZ, Meng F, Tsavaler L, Evans SJ, Choudary PV, Tomita H, Vawter MP, Walsh D, Shokoohi V, Chung T, Bunney WE, Jones EG, Akil H, Watson SJ, Myers RM. Sample matching by inferred agonal stress in gene expression analyses of the brain. Bmc Genomics. 8: 336. PMID 17892578 DOI: 10.1186/1471-2164-8-336  0.534
2007 Ballaz SJ, Akil H, Watson SJ. The 5-HT7 receptor: role in novel object discrimination and relation to novelty-seeking behavior. Neuroscience. 149: 192-202. PMID 17869441 DOI: 10.1016/j.neuroscience.2007.07.043  0.516
2007 Wei Q, Hebda-Bauer EK, Pletsch A, Luo J, Hoversten MT, Osetek AJ, Evans SJ, Watson SJ, Seasholtz AF, Akil H. Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8836-44. PMID 17699665 DOI: 10.1523/Jneurosci.0910-07.2007  0.529
2007 Ballaz SJ, Akil H, Watson SJ. Analysis of 5-HT6 and 5-HT7 receptor gene expression in rats showing differences in novelty-seeking behavior. Neuroscience. 147: 428-38. PMID 17543469 DOI: 10.1016/j.neuroscience.2007.04.024  0.539
2007 Atz M, Walsh D, Cartagena P, Li J, Evans S, Choudary P, Overman K, Stein R, Tomita H, Potkin S, Myers R, Watson SJ, Jones EG, Akil H, Bunney WE, et al. Methodological considerations for gene expression profiling of human brain. Journal of Neuroscience Methods. 163: 295-309. PMID 17512057 DOI: 10.1016/J.Jneumeth.2007.03.022  0.528
2007 Buck BJ, Kerman IA, Burghardt PR, Koch LG, Britton SL, Akil H, Watson SJ. Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome. Neuroscience Letters. 419: 178-83. PMID 17490814 DOI: 10.1016/j.neulet.2007.04.042  0.747
2007 Clinton SM, Vázquez DM, Kabbaj M, Kabbaj MH, Watson SJ, Akil H. Individual differences in novelty-seeking and emotional reactivity correlate with variation in maternal behavior. Hormones and Behavior. 51: 655-64. PMID 17462647 DOI: 10.1016/J.Yhbeh.2007.03.009  0.526
2007 Flagel SB, Watson SJ, Robinson TE, Akil H. Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats. Psychopharmacology. 191: 599-607. PMID 16972103 DOI: 10.1007/s00213-006-0535-8  0.655
2007 Cecchi M, Capriles N, Watson SJ, Akil H. Beta1 adrenergic receptors in the bed nucleus of stria terminalis mediate differential responses to opiate withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 589-99. PMID 16823388 DOI: 10.1038/Sj.Npp.1301140  0.583
2007 Sliwerska E, Meng F, Speed TP, Jones EG, Bunney WE, Akil H, Watson SJ, Burmeister M. SNPs on chips: the hidden genetic code in expression arrays. Biological Psychiatry. 61: 13-6. PMID 16690034 DOI: 10.1016/J.Biopsych.2006.01.023  0.521
2006 Kerman IA, Shabrang C, Taylor L, Akil H, Watson SJ. Relationship of presympathetic-premotor neurons to the serotonergic transmitter system in the rat brainstem. The Journal of Comparative Neurology. 499: 882-96. PMID 17072838 DOI: 10.1002/cne.21129  0.75
2006 Vawter MP, Tomita H, Meng F, Bolstad B, Li J, Evans S, Choudary P, Atz M, Shao L, Neal C, Walsh DM, Burmeister M, Speed T, Myers R, Jones EG, ... Watson SJ, et al. Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders. Molecular Psychiatry. 11: 615, 663-79. PMID 16636682 DOI: 10.1038/Sj.Mp.4001830  0.518
2006 Turner CA, Akil H, Watson SJ, Evans SJ. The fibroblast growth factor system and mood disorders. Biological Psychiatry. 59: 1128-35. PMID 16631131 DOI: 10.1016/J.Biopsych.2006.02.026  0.548
2006 Kerman IA, Akil H, Watson SJ. Rostral elements of sympatho-motor circuitry: a virally mediated transsynaptic tracing study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3423-33. PMID 16571749 DOI: 10.1523/JNEUROSCI.5283-05.2006  0.737
2006 Zhang H, Torregrossa MM, Jutkiewicz EM, Shi YG, Rice KC, Woods JH, Watson SJ, Ko MC. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. The European Journal of Neuroscience. 23: 984-94. PMID 16519663 DOI: 10.1111/J.1460-9568.2006.04621.X  0.631
2006 Stead JD, Clinton S, Neal C, Schneider J, Jama A, Miller S, Vazquez DM, Watson SJ, Akil H. Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors. Behavior Genetics. 36: 697-712. PMID 16502134 DOI: 10.1007/S10519-006-9058-7  0.549
2006 Karssen AM, Li JZ, Her S, Patel PD, Meng F, Evans SJ, Vawter MP, Tomita H, Choudary PV, Bunney WE, Jones EG, Watson SJ, Akil H, Myers RM, Schatzberg AF, et al. Application of microarray technology in primate behavioral neuroscience research. Methods (San Diego, Calif.). 38: 227-34. PMID 16469505 DOI: 10.1016/J.Ymeth.2005.09.017  0.541
2006 Jutkiewicz EM, Torregrossa MM, Sobczyk-Kojiro K, Mosberg HI, Folk JE, Rice KC, Watson SJ, Woods JH. Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects. European Journal of Pharmacology. 531: 151-9. PMID 16442521 DOI: 10.1016/J.Ejphar.2005.12.002  0.618
2006 Stead JD, Neal C, Meng F, Wang Y, Evans S, Vazquez DM, Watson SJ, Akil H. Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 345-53. PMID 16399705 DOI: 10.1523/Jneurosci.2755-05.2006  0.556
2006 Torregrossa MM, Jutkiewicz EM, Mosberg HI, Balboni G, Watson SJ, Woods JH. Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats. Brain Research. 1069: 172-81. PMID 16364263 DOI: 10.1016/J.Brainres.2005.11.005  0.628
2006 Kerman IA, Buck BJ, Evans SJ, Akil H, Watson SJ. Combining laser capture microdissection with quantitative real-time PCR: effects of tissue manipulation on RNA quality and gene expression. Journal of Neuroscience Methods. 153: 71-85. PMID 16337273 DOI: 10.1016/j.jneumeth.2005.10.010  0.74
2006 Vawter MP, Tomita H, Meng F, Bolstad B, Li J, Evans S, Choudary P, Atz M, Shao L, Neal C, Walsh DM, Burmeister M, Speed T, Myers R, Jones EG, ... Watson SJ, et al. Mitochondrial related gene expression changes are sensitive to agonal-pH state Molecular Psychiatry. 11: 615-615. DOI: 10.1038/Sj.Mp.4001850  0.48
2005 Dai M, Wang P, Boyd AD, Kostov G, Athey B, Jones EG, Bunney WE, Myers RM, Speed TP, Akil H, Watson SJ, Meng F. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Research. 33: e175. PMID 16284200 DOI: 10.1093/Nar/Gni179  0.5
2005 Choudary PV, Molnar M, Evans SJ, Tomita H, Li JZ, Vawter MP, Myers RM, Bunney WE, Akil H, Watson SJ, Jones EG. Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. Proceedings of the National Academy of Sciences of the United States of America. 102: 15653-8. PMID 16230605 DOI: 10.1073/Pnas.0507901102  0.512
2005 Torregrossa MM, Folk JE, Rice KC, Watson SJ, Woods JH. Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats. Psychopharmacology. 183: 31-40. PMID 16220339 DOI: 10.1007/S00213-005-0113-5  0.625
2005 Hebda-Bauer EK, Watson SJ, Akil H. Cognitive performance is highly sensitive to prior experience in mice with a learning and memory deficit: failure leads to more failure. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 461-71. PMID 16166394 DOI: 10.1101/lm.94105  0.466
2005 Helmreich DL, Parfitt DB, Lu XY, Akil H, Watson SJ. Relation between the hypothalamic-pituitary-thyroid (HPT) axis and the hypothalamic-pituitary-adrenal (HPA) axis during repeated stress. Neuroendocrinology. 81: 183-92. PMID 16020927 DOI: 10.1159/000087001  0.544
2005 Shieh KR, Yang SC, Lu XY, Akil H, Watson SJ. Diurnal rhythmic expression of the rhythm-related genes, rPeriod1, rPeriod2, and rClock, in the rat brain. Journal of Biomedical Science. 12: 209-17. PMID 15864751 DOI: 10.1007/s11373-004-8176-6  0.578
2004 Evans SJ, Choudary PV, Neal CR, Li JZ, Vawter MP, Tomita H, Lopez JF, Thompson RC, Meng F, Stead JD, Walsh DM, Myers RM, Bunney WE, Watson SJ, Jones EG, et al. Dysregulation of the fibroblast growth factor system in major depression. Proceedings of the National Academy of Sciences of the United States of America. 101: 15506-11. PMID 15483108 DOI: 10.1073/Pnas.0406788101  0.553
2004 Kabbaj M, Evans S, Watson SJ, Akil H. The search for the neurobiological basis of vulnerability to drug abuse: using microarrays to investigate the role of stress and individual differences. Neuropharmacology. 47: 111-22. PMID 15464130 DOI: 10.1016/J.Neuropharm.2004.07.021  0.514
2004 Isgor C, Kabbaj M, Akil H, Watson SJ. Delayed effects of chronic variable stress during peripubertal-juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats. Hippocampus. 14: 636-48. PMID 15301440 DOI: 10.1002/Hipo.10207  0.526
2004 Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H. Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proceedings of the National Academy of Sciences of the United States of America. 101: 11851-6. PMID 15280545 DOI: 10.1073/Pnas.0402208101  0.659
2004 Hebda-Bauer EK, Watson SJ, Akil H. CREB deficient mice show inhibition and low activity in novel environments without changes in stress reactivity. The European Journal of Neuroscience. 20: 503-13. PMID 15233759 DOI: 10.1111/j.1460-9568.2004.03487.x  0.499
2004 Tomita H, Vawter MP, Walsh DM, Evans SJ, Choudary PV, Li J, Overman KM, Atz ME, Myers RM, Jones EG, Watson SJ, Akil H, Bunney WE. Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biological Psychiatry. 55: 346-52. PMID 14960286 DOI: 10.1016/J.Biopsych.2003.10.013  0.528
2004 Erb S, Funk D, Borkowski S, Watson SJ, Akil H. Effects of chronic cocaine exposure on corticotropin-releasing hormone binding protein in the central nucleus of the amygdala and bed nucleus of the stria terminalis. Neuroscience. 123: 1003-9. PMID 14751291 DOI: 10.1016/j.neuroscience.2003.10.031  0.566
2004 López-Figueroa AL, Norton CS, López-Figueroa MO, Armellini-Dodel D, Burke S, Akil H, López JF, Watson SJ. Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia. Biological Psychiatry. 55: 225-33. PMID 14744462 DOI: 10.1016/J.Biopsych.2003.09.017  0.502
2004 Li JZ, Vawter MP, Walsh DM, Tomita H, Evans SJ, Choudary PV, Lopez JF, Avelar A, Shokoohi V, Chung T, Mesarwi O, Jones EG, Watson SJ, Akil H, Bunney WE, et al. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Human Molecular Genetics. 13: 609-16. PMID 14734628 DOI: 10.1093/Hmg/Ddh065  0.544
2004 Torregrossa MM, Isgor C, Folk JE, Rice KC, Watson SJ, Woods JH. The delta-opioid receptor agonist (+)BW373U86 regulates BDNF mRNA expression in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 649-59. PMID 14647482 DOI: 10.1038/Sj.Npp.1300345  0.634
2004 Vawter MP, Evans S, Choudary P, Tomita H, Meador-Woodruff J, Molnar M, Li J, Lopez JF, Myers R, Cox D, Watson SJ, Akil H, Jones EG, Bunney WE. Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 373-84. PMID 14583743 DOI: 10.1038/Sj.Npp.1300337  0.546
2003 Evans SJ, Watson SJ, Akil H. Evaluation of sensitivity, performance and reproducibility of microarray technology in neuronal tissue. Integrative and Comparative Biology. 43: 780-5. PMID 21680476 DOI: 10.1093/icb/43.6.780  0.495
2003 Isgor C, Cecchi M, Kabbaj M, Akil H, Watson SJ. Estrogen receptor beta in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone. Neuroscience. 121: 837-45. PMID 14580933 DOI: 10.1016/S0306-4522(03)00561-X  0.584
2003 Morgan C, Thompson RC, Watson SJ, Akil H. Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression. General and Comparative Endocrinology. 133: 353-7. PMID 12957479 DOI: 10.1016/S0016-6480(03)00189-8  0.527
2003 Lu XY, Barsh GS, Akil H, Watson SJ. Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7863-72. PMID 12944516 DOI: 10.1523/Jneurosci.23-21-07863.2003  0.55
2003 Neal CR, Owens CE, Taylor LP, Hoversten MT, Akil H, Watson SJ. Binding and GTPgammaS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors. Journal of Chemical Neuroanatomy. 25: 233-47. PMID 12842269 DOI: 10.1016/S0891-0618(03)00032-2  0.539
2003 Ferguson SM, Norton CS, Watson SJ, Akil H, Robinson TE. Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context. Journal of Neurochemistry. 86: 33-44. PMID 12807422 DOI: 10.1046/J.1471-4159.2003.01815.X  0.66
2003 Kerman IA, Enquist LW, Watson SJ, Yates BJ. Brainstem substrates of sympatho-motor circuitry identified using trans-synaptic tracing with pseudorabies virus recombinants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4657-66. PMID 12805305 DOI: 10.1523/Jneurosci.23-11-04657.2003  0.723
2003 Isgor C, Shieh KR, Akil H, Watson SJ. Colocalization of estrogen beta-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei. Anatomy and Embryology. 206: 461-9. PMID 12690447 DOI: 10.1007/s00429-003-0314-9  0.591
2003 Gordon NS, Burke S, Akil H, Watson SJ, Panksepp J. Socially-induced brain 'fertilization': play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats. Neuroscience Letters. 341: 17-20. PMID 12676333 DOI: 10.1016/S0304-3940(03)00158-7  0.566
2003 Bunney WE, Bunney BG, Vawter MP, Tomita H, Li J, Evans SJ, Choudary PV, Myers RM, Jones EG, Watson SJ, Akil H. Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. The American Journal of Psychiatry. 160: 657-66. PMID 12668351 DOI: 10.1176/Appi.Ajp.160.4.657  0.498
2003 Uslaner JM, Norton CS, Watson SJ, Akil H, Robinson TE. Amphetamine-induced c-fos mRNA expression in the caudate-putamen and subthalamic nucleus: interactions between dose, environment, and neuronal phenotype. Journal of Neurochemistry. 85: 105-14. PMID 12641732 DOI: 10.1046/J.1471-4159.2003.01646.X  0.642
2003 Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. Mineralocorticoid receptor function in major depression. Archives of General Psychiatry. 60: 24-8. PMID 12511169 DOI: 10.1001/Archpsyc.60.1.24  0.544
2002 Nicholson JR, Akil H, Watson SJ. Orphanin FQ-induced hyperphagia is mediated by corticosterone and central glucocorticoid receptors. Neuroscience. 115: 637-43. PMID 12421628 DOI: 10.1016/S0306-4522(02)00290-7  0.517
2002 Isgor C, Huang GC, Akil H, Watson SJ. Correlation of estrogen beta-receptor messenger RNA with endogenous levels of plasma estradiol and progesterone in the female rat hypothalamus, the bed nucleus of stria terminalis and the medial amygdala. Brain Research. Molecular Brain Research. 106: 30-41. PMID 12393262 DOI: 10.1016/S0169-328X(02)00407-2  0.587
2002 Lu XY, Shieh KR, Kabbaj M, Barsh GS, Akil H, Watson SJ. Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake. Endocrinology. 143: 3905-15. PMID 12239102 DOI: 10.1210/En.2002-220150  0.537
2002 Evans SJ, Datson NA, Kabbaj M, Thompson RC, Vreugdenhil E, De Kloet ER, Watson SJ, Akil H. Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis. Serial Analysis of Gene Expression. The European Journal of Neuroscience. 16: 409-13. PMID 12193183 DOI: 10.1046/J.1460-9568.2002.02097.X  0.539
2002 Campeau S, Dolan D, Akil H, Watson SJ. c-fos mRNA induction in acute and chronic audiogenic stress: possible role of the orbitofrontal cortex in habituation. Stress (Amsterdam, Netherlands). 5: 121-30. PMID 12186690 DOI: 10.1080/10253890290027895  0.551
2002 Kabbaj M, Isgor C, Watson SJ, Akil H. Stress during adolescence alters behavioral sensitization to amphetamine. Neuroscience. 113: 395-400. PMID 12127096 DOI: 10.1016/S0306-4522(02)00188-4  0.526
2002 Day HE, Vittoz NM, Oates MM, Badiani A, Watson SJ, Robinson TE, Akil H. A 6-hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis. Brain Research. 945: 151-9. PMID 12126877 DOI: 10.1016/S0006-8993(02)02747-6  0.664
2002 López-Figueroa MO, Caamaño CA, Morano MI, Akil H, Watson SJ. Fluorescent imaging of mitochondrial nitric oxide in living cells. Methods in Enzymology. 352: 296-303. PMID 12125355 DOI: 10.1016/S0076-6879(02)52027-9  0.463
2002 Norton CS, Neal CR, Kumar S, Akil H, Watson SJ. Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems. The Journal of Comparative Neurology. 444: 358-68. PMID 11891648 DOI: 10.1002/cne.10154  0.531
2002 Klebaur JE, Ostrander MM, Norton CS, Watson SJ, Akil H, Robinson TE. The ability of amphetamine to evoke arc (Arg 3.1) mRNA expression in the caudate, nucleus accumbens and neocortex is modulated by environmental context. Brain Research. 930: 30-6. PMID 11879792 DOI: 10.1016/S0006-8993(01)03400-X  0.684
2002 Neal CR, Akil H, Watson SJ. Chapter III Neuroanatomical studies of the opioid receptor-like-1 receptor and its endogenous neuropeptide orphanin FQ (nociceptin) Handbook of Chemical Neuroanatomy. 20: 103-193. DOI: 10.1016/S0924-8196(02)80005-7  0.522
2001 Neal CR, Akil H, Watson SJ. Expression of orphanin FQ and the opioid receptor-like (ORL1) receptor in the developing human and rat brain. Journal of Chemical Neuroanatomy. 22: 219-49. PMID 11719021 DOI: 10.1016/S0891-0618(01)00135-1  0.594
2001 Uslaner J, Badiani A, Day HE, Watson SJ, Akil H, Robinson TE. Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens. Brain Research. 920: 106-16. PMID 11716816 DOI: 10.1016/S0006-8993(01)03040-2  0.67
2001 López-Figueroa MO, Caamaño C, Marin R, Guerra B, Alonso R, Morano MI, Akil H, Watson SJ. Characterization of basal nitric oxide production in living cells. Biochimica Et Biophysica Acta. 1540: 253-64. PMID 11583820 DOI: 10.1016/S0167-4889(01)00138-0  0.492
2001 Uslaner J, Badiani A, Norton CS, Day HE, Watson SJ, Akil H, Robinson TE. Amphetamine and cocaine induce different patterns of c-fos mRNA expression in the striatum and subthalamic nucleus depending on environmental context. The European Journal of Neuroscience. 13: 1977-83. PMID 11403691 DOI: 10.1046/J.0953-816X.2001.01574.X  0.659
2001 Lu XY, Nicholson JR, Akil H, Watson SJ. Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132). Neuroreport. 12: 1281-4. PMID 11338207 DOI: 10.1097/00001756-200105080-00045  0.495
2001 Helmreich DL, Itoi K, Lopez-Figueroa MO, Akil H, Watson SJ. Norepinephrine-induced CRH and AVP gene transcription within the hypothalamus: differential regulation by corticosterone. Brain Research. Molecular Brain Research. 88: 62-73. PMID 11295232 DOI: 10.1016/S0169-328X(01)00018-3  0.556
2001 Devine DP, Watson SJ, Akil H. Nociceptin/orphanin FQ regulates neuroendocrine function of the limbic-hypothalamic-pituitary-adrenal axis. Neuroscience. 102: 541-53. PMID 11226692 DOI: 10.1016/S0306-4522(00)00517-0  0.542
2001 Day HE, Badiani A, Uslaner JM, Oates MM, Vittoz NM, Robinson TE, Watson SJ, Akil H. Environmental novelty differentially affects c-fos mRNA expression induced by amphetamine or cocaine in subregions of the bed nucleus of the stria terminalis and amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 732-40. PMID 11160452 DOI: 10.1523/Jneurosci.21-02-00732.2001  0.666
2000 Watson SJ, Meng F, Thompson RC, Akil H. The "chip" as a specific genetic tool. Biological Psychiatry. 48: 1147-56. PMID 11137056 DOI: 10.1016/S0006-3223(00)01080-5  0.512
2000 Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. Hormonal evidence for altered responsiveness to social stress in major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 411-8. PMID 10989268 DOI: 10.1016/S0893-133X(00)00129-9  0.521
2000 López-Figueroa MO, Caamaño C, Morano MI, Rønn LC, Akil H, Watson SJ. Direct evidence of nitric oxide presence within mitochondria. Biochemical and Biophysical Research Communications. 272: 129-33. PMID 10872815 DOI: 10.1006/bbrc.2000.2748  0.463
2000 Lu XY, Bagnol D, Burke S, Akil H, Watson SJ. Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting. Hormones and Behavior. 37: 335-44. PMID 10860677 DOI: 10.1006/hbeh.2000.1584  0.569
2000 López-Figueroa MO, Day HE, Lee S, Rivier C, Akil H, Watson SJ. Temporal and anatomical distribution of nitric oxide synthase mRNA expression and nitric oxide production during central nervous system inflammation. Brain Research. 852: 239-46. PMID 10661521 DOI: 10.1016/S0006-8993(99)02241-6  0.529
2000 Akil H, Watson SJ. Science and the future of psychiatry. Archives of General Psychiatry. 57: 86-7. PMID 10632238 DOI: 10.1001/Archpsyc.57.1.86  0.5
2000 Bishop GB, Curran EJ, Watson SJ, Akil H, Gutstein HB. Room D, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Chronic Administration of Opioids and Psychostimulants Alter RGS4 mRNA Levels in Rat Brain Anesthesiology. 93: A-779. DOI: 10.1097/00000542-200009001-00779  0.549
2000 Bishop G, Curran E, Watson S, Akil H, Gutstein, M.D., Anesthesiology H. Room 302, 10/17/2000 9: 00 AM - 10: 30 AM (PD) Acute Treatment with Opioids and Stimulants Alter RGS4 mRNA Levels in Rat Brain  Anesthesiology. 93: A-127. DOI: 10.1097/00000542-200009001-00127  0.536
2000 Young E, López J, Weinberg V, Watson S, Akil H. 215. Altered hormonal response to a social stressor in major depression Biological Psychiatry. 47: S65-S66. DOI: 10.1016/S0006-3223(00)00479-0  0.498
2000 Watson S, Thompson R, Meng F, Akil H. 191. Gene expression arrays: their power and their limits Biological Psychiatry. 47: S58. DOI: 10.1016/S0006-3223(00)00455-8  0.487
1999 Herman JP, Watson SJ, Spencer RL. Defense of Adrenocorticosteroid Receptor Expression in Rat Hippocampus: Effects of Stress and Strain1. Endocrinology. 140: 3981-3991. PMID 28200831 DOI: 10.1210/endo.140.9.6962  0.458
1999 López JF, Akil H, Watson SJ. Neural circuits mediating stress. Biological Psychiatry. 46: 1461-71. PMID 10599476 DOI: 10.1016/S0006-3223(99)00266-8  0.514
1999 Lu Xy, Gunn TM, Shieh Kr, Barsh GS, Akil H, Watson SJ. Distribution of Mahogany/Attractin mRNA in the rat central nervous system. Febs Letters. 462: 101-7. PMID 10580100 DOI: 10.1016/S0014-5793(99)01494-5  0.552
1999 Day HE, Campeau S, Watson SJ, Akil H. Expression of alpha(1b) adrenoceptor mRNA in corticotropin-releasing hormone-containing cells of the rat hypothalamus and its regulation by corticosterone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10098-106. PMID 10559417  0.55
1999 Badiani A, Oates MM, Day HE, Watson SJ, Akil H, Robinson TE. Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons. Behavioural Brain Research. 103: 203-9. PMID 10513588 DOI: 10.1016/S0166-4328(99)00041-8  0.655
1999 Bagnol D, Lu XY, Kaelin CB, Day HE, Ollmann M, Gantz I, Akil H, Barsh GS, Watson SJ. Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC26. PMID 10479719 DOI: 10.1523/Jneurosci.19-18-J0004.1999  0.558
1999 Herman JP, Watson SJ, Spencer RL. Defense of adrenocorticosteroid receptor expression in rat hippocampus: effects of stress and strain. Endocrinology. 140: 3981-91. PMID 10465267 DOI: 10.1210/Endo.140.9.6962  0.477
1999 Day HE, Curran EJ, Watson SJ, Akil H. Distinct neurochemical populations in the rat central nucleus of the amygdala and bed nucleus of the stria terminalis: evidence for their selective activation by interleukin-1beta. The Journal of Comparative Neurology. 413: 113-28. PMID 10464374 DOI: 10.1002/(SICI)1096-9861(19991011)413:1<113::AID-CNE8>3.0.CO;2-B  0.569
1999 Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Akil H, Watson SJ. Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding. The Journal of Comparative Neurology. 412: 563-605. PMID 10464356 DOI: 10.1002/(Sici)1096-9861(19991004)412:4<563::Aid-Cne2>3.0.Co;2-Z  0.581
1999 Watson SJ, Akil H. Gene chips and arrays revealed: a primer on their power and their uses. Biological Psychiatry. 45: 533-43. PMID 10088043 DOI: 10.1016/S0006-3223(98)00339-4  0.521
1999 Neal CR, Akil H, Watson SJ. The Orphanin FQ (ORL1) Receptor: Expression of a Novel Opioid-Like Receptor in the Central Nervous System of the Developing Rat and Human Brain Pediatric Research. 45: 345A-345A. DOI: 10.1203/00006450-199904020-02050  0.569
1998 Va Zquez DM, Lo Pez JF, Morano MA, Kwak SP, Watson SJ, Akil H. α, β, and γ Mineralocorticoid Receptor Messenger Ribonucleic Acid Splice Variants: Differential Expression and Rapid Regulation in the Developing Hippocampus. Endocrinology. 139: 3165-3177. PMID 28200470 DOI: 10.1210/endo.139.7.6095  0.506
1998 López-Figueroa MO, Day HE, Akil H, Watson SJ. Nitric oxide in the stress axis. Histology and Histopathology. 13: 1243-52. PMID 9810515  0.52
1998 Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans. The Journal of Clinical Endocrinology and Metabolism. 83: 3339-45. PMID 9745451 DOI: 10.1210/jcem.83.9.5077  0.535
1998 Akil H, Owens C, Gutstein H, Taylor L, Curran E, Watson S. Endogenous opioids: overview and current issues. Drug and Alcohol Dependence. 51: 127-40. PMID 9716935 DOI: 10.1016/S0376-8716(98)00071-4  0.575
1998 Gutstein HB, Thome JL, Fine JL, Watson SJ, Akil H. Pattern of c-fos mRNA induction in rat brain by acute morphine. Canadian Journal of Physiology and Pharmacology. 76: 294-303. PMID 9673793 DOI: 10.1139/cjpp-76-3-294  0.579
1998 Gutstein HB, Mansour A, Watson SJ, Akil H, Fields HL. Mu and kappa opioid receptors in periaqueductal gray and rostral ventromedial medulla. Neuroreport. 9: 1777-81. PMID 9665599 DOI: 10.1097/00001756-199806010-00019  0.532
1998 Vázquez DM, López JF, Morano MI, Kwak SP, Watson SJ, Akil H. Alpha, beta, and gamma mineralocorticoid receptor messenger ribonucleic acid splice variants: differential expression and rapid regulation in the developing hippocampus. Endocrinology. 139: 3165-77. PMID 9645690 DOI: 10.1210/Endo.139.7.6095  0.586
1998 Meng F, Ueda Y, Hoversten MT, Taylor LP, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H. Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis. Molecular Pharmacology. 53: 772-7. PMID 9547370 DOI: 10.1124/Mol.53.4.772  0.521
1998 Badiani A, Oates MM, Day HEW, Watson SJ, Akil H, Robinson TE. Amphetamine-Induced Behavior, Dopamine Release, and c-fosmRNA Expression: Modulation by Environmental Novelty The Journal of Neuroscience. 18: 10579-10593. DOI: 10.1523/JNEUROSCI.18-24-10579.1998  0.624
1998 Gutstein H, Cullinan W, Thome J, Watson S, Akil H. DOES THE INTENSITY OF NOXIOUS STIMULATION INFLUENCE C-FOS ACTIVATION PATTERNS IN RAT BRAIN? Anesthesia & Analgesia. 86: 273S. DOI: 10.1097/00000539-199802001-00271  0.521
1997 Bagnol D, Mansour A, Akil H, Watson SJ. Cellular localization and distribution of the cloned mu and kappa opioid receptors in rat gastrointestinal tract. Neuroscience. 81: 579-91. PMID 9300443 DOI: 10.1016/S0306-4522(97)00227-3  0.545
1997 Day HE, Campeau S, Watson SJ, Akil H. Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord. Journal of Chemical Neuroanatomy. 13: 115-39. PMID 9285356 DOI: 10.1016/S0891-0618(97)00042-2  0.537
1997 Campeau S, Akil H, Watson SJ. Lesions of the medial geniculate nuclei specifically block corticosterone release and induction of c-fos mRNA in the forebrain associated with audiogenic stress in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5979-92. PMID 9221794 DOI: 10.1523/Jneurosci.17-15-05979.1997  0.561
1997 Fickel J, Bagnol D, Watson SJ, Akil H. Opioid receptor expression in the rat gastrointestinal tract: a quantitative study with comparison to the brain. Brain Research. Molecular Brain Research. 46: 1-8. PMID 9191072 DOI: 10.1016/S0169-328X(96)00266-5  0.578
1997 Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. Normal pituitary response to metyrapone in the morning in depressed patients: implications for circadian regulation of corticotropin-releasing hormone secretion. Biological Psychiatry. 41: 1149-55. PMID 9171905 DOI: 10.1016/S0006-3223(96)00291-0  0.521
1997 Mansour A, Taylor LP, Fine JL, Thompson RC, Hoversten MT, Mosberg HI, Watson SJ, Akil H. Key residues defining the mu-opioid receptor binding pocket: a site-directed mutagenesis study. Journal of Neurochemistry. 68: 344-53. PMID 8978745 DOI: 10.1046/J.1471-4159.1997.68010344.X  0.517
1997 Watson S, Akil H. Molecular and circuit targets for drug development in the brain's stress systems Biological Psychiatry. 42: 274S. DOI: 10.1016/S0006-3223(97)88054-7  0.493
1997 Watson S, Akil H. How does the brain regulate the stress response: Anatomical and biochemical perspectives Biological Psychiatry. 42: 150S. DOI: 10.1016/S0006-3223(97)87504-X  0.516
1997 Akil H, Meng F, Devine DP, Watson SJ. Molecular and neuroanatomical properties of the endogenous opioid system: Implications for treatment of opiate addiction Seminars in the Neurosciences. 9: 70-83. DOI: 10.1006/smns.1997.0108  0.531
1996 Curran EJ, Akil H, Watson SJ. Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: comparisons between acute drug treatment and a drug challenge in sensitized animals. Neurochemical Research. 21: 1425-35. PMID 8947933 DOI: 10.1007/BF02532384  0.548
1996 Meng F, Taylor LP, Hoversten MT, Ueda Y, Ardati A, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H. Moving from the orphanin FQ receptor to an opioid receptor using four point mutations. The Journal of Biological Chemistry. 271: 32016-20. PMID 8943250 DOI: 10.1074/Jbc.271.50.32016  0.524
1996 Meng F, Ueda Y, Hoversten MT, Thompson RC, Taylor L, Watson SJ, Akil H. Mapping the receptor domains critical for the binding selectivity of delta-opioid receptor ligands. European Journal of Pharmacology. 311: 285-92. PMID 8891611 DOI: 10.1016/0014-2999(96)00431-1  0.524
1996 Mansour A, Burke S, Pavlic RJ, Akil H, Watson SJ. Immunohistochemical localization of the cloned kappa 1 receptor in the rat CNS and pituitary. Neuroscience. 71: 671-90. PMID 8867040 DOI: 10.1016/0306-4522(95)00464-5  0.576
1996 Akil H, Meng F, Mansour A, Thompson R, Xie GX, Watson S. Cloning and characterization of multiple opioid receptors. Nida Research Monograph. 161: 127-40. PMID 8784848  0.513
1996 Ruzicka BB, Thompson RC, Watson SJ, Akil H. Interleukin-1 beta-mediated regulation of mu-opioid receptor mRNA in primary astrocyte-enriched cultures. Journal of Neurochemistry. 66: 425-8. PMID 8522984 DOI: 10.1046/j.1471-4159.1996.66010425.x  0.555
1996 Vázquez D, Kwak S, López J, Watson S, Akil H. Mineralocorticoid receptor mRNA variants in the developing hippocampus: Distribution and regulation European Neuropsychopharmacology. 6: 84. DOI: 10.1016/0924-977X(96)87688-7  0.537
1995 Ruzicka BB, Fox CA, Thompson RC, Meng F, Watson SJ, Akil H. Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA. Brain Research. Molecular Brain Research. 34: 209-20. PMID 8750824 DOI: 10.1016/0169-328X(95)00165-O  0.566
1995 Mansour A, Hoversten MT, Taylor LP, Watson SJ, Akil H. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Research. 700: 89-98. PMID 8624732 DOI: 10.1016/0006-8993(95)00928-J  0.528
1995 Young EA, Akil H, Haskett RF, Watson SJ. Evidence against changes in corticotroph CRF receptors in depressed patients. Biological Psychiatry. 37: 355-63. PMID 7772643 DOI: 10.1016/0006-3223(94)00153-T  0.526
1995 Meng F, Hoversten MT, Thompson RC, Taylor L, Watson SJ, Akil H. A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains. The Journal of Biological Chemistry. 270: 12730-6. PMID 7759527 DOI: 10.1074/JBC.270.21.12730  0.52
1995 Cullinan WE, Herman JP, Battaglia DF, Akil H, Watson SJ. Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience. 64: 477-505. PMID 7700534 DOI: 10.1016/0306-4522(94)00355-9  0.655
1995 Mansour A, Fox CA, Burke S, Akil H, Watson SJ. Immunohistochemical localization of the cloned mu opioid receptor in the rat CNS. Journal of Chemical Neuroanatomy. 8: 283-305. PMID 7669273 DOI: 10.1016/0891-0618(95)00055-C  0.565
1995 Caamaño CA, Morano MI, Dalman FC, Hoversten MT, Watson SJ, Pratt WB, Akil H. Point mutations in the 90-kDa heat shock protein binding region of the glucocorticoid receptor affect the functional characteristics of the receptor. Annals of the New York Academy of Sciences. 761: 403-4. PMID 7625747 DOI: 10.1111/J.1749-6632.1995.Tb31403.X  0.503
1995 Herman JP, Watson SJ. Stress regulation of mineralocorticoid receptor heteronuclear RNA in rat hippocampus. Brain Research. 677: 243-9. PMID 7552249 DOI: 10.1016/0006-8993(95)00152-G  0.492
1995 Herman JP, Cullinan WE, Morano MI, Akil H, Watson SJ. Contribution of the ventral subiculum to inhibitory regulation of the hypothalamo-pituitary-adrenocortical axis. Journal of Neuroendocrinology. 7: 475-82. PMID 7550295 DOI: 10.1111/J.1365-2826.1995.Tb00784.X  0.657
1995 Mansour A, Watson SJ, Akil H. Opioid receptors: past, present and future. Trends in Neurosciences. 18: 69-70. PMID 7537414 DOI: 10.1016/0166-2236(95)80024-V  0.511
1995 Mansour A, Fox CA, Akil H, Watson SJ. Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends in Neurosciences. 18: 22-9. PMID 7535487 DOI: 10.1016/0166-2236(95)93946-U  0.555
1995 Bagnol D, Mansour A, Akil H, Watson S. LOCALIZATION OF MU AND KAPPA OPIOID RECEPTORS IN RAT COLON BY ANTIBODIES TO THE CLONED OPIOID RECEPTORS. Analgesia. 1: 264-267. DOI: 10.3727/107156995819563267  0.525
1995 Bagnol D, Mansour A, Akil H, Watson S. DISTRIBUTION OF PROENKEPHALIN mRNA IN THE RAT DISTAL COLON: AN IN SITU HYBRIDIZATION STUDY. Analgesia. 1: 260-263. DOI: 10.3727/107156995819563159  0.528
1995 Mansour A, Hoversten MT, Mansson E, Bare L, Watson SJ, Akil H. APPARENT EVIDENCE OF RECEPTOR SUBTYPES: RECEPTOR BINDING STUDIES WITH THE CLONED RAT AND HUMAN KAPPA RECEPTORS Analgesia. 1: 553-556. DOI: 10.3727/107156995819563096  0.528
1994 López JF, Chalmers DT, Vázquez DM, Watson SJ, Akil H. Serotonin transporter mRNA in rat brain is regulated by classical antidepressants. Biological Psychiatry. 35: 287-90. PMID 8186335 DOI: 10.1016/0006-3223(94)91262-9  0.57
1994 Xie GX, Meng F, Mansour A, Thompson RC, Hoversten MT, Goldstein A, Watson SJ, Akil H. Primary structure and functional expression of a guinea pig kappa opioid (dynorphin) receptor. Proceedings of the National Academy of Sciences of the United States of America. 91: 3779-83. PMID 8170987 DOI: 10.1073/Pnas.91.9.3779  0.562
1994 Young EA, Haskett RF, Grunhaus L, Pande A, Weinberg VM, Watson SJ, Akil H. Increased evening activation of the hypothalamic-pituitary-adrenal axis in depressed patients. Archives of General Psychiatry. 51: 701-7. PMID 8080346 DOI: 10.1001/Archpsyc.1994.03950090033005  0.516
1994 Meng F, Xie GX, Chalmers D, Morgan C, Watson SJ, Akil H. Cloning and expression of the A2a adenosine receptor from guinea pig brain. Neurochemical Research. 19: 613-21. PMID 8065518 DOI: 10.1007/Bf00971338  0.54
1994 Mansour A, Fox CA, Thompson RC, Akil H, Watson SJ. mu-Opioid receptor mRNA expression in the rat CNS: comparison to mu-receptor binding. Brain Research. 643: 245-65. PMID 8032920 DOI: 10.1016/0006-8993(94)90031-0  0.564
1994 Mansour A, Fox CA, Meng F, Akil H, Watson SJ. Kappa 1 receptor mRNA distribution in the rat CNS: comparison to kappa receptor binding and prodynorphin mRNA. Molecular and Cellular Neurosciences. 5: 124-44. PMID 8032682 DOI: 10.1006/mcne.1994.1015  0.572
1994 Herman JP, Cullinan WE, Watson SJ. Involvement of the bed nucleus of the stria terminalis in tonic regulation of paraventricular hypothalamic CRH and AVP mRNA expression. Journal of Neuroendocrinology. 6: 433-42. PMID 7987374 DOI: 10.1111/J.1365-2826.1994.Tb00604.X  0.473
1994 Akil H, Watson SJ. Cloning of kappa opioid receptors: functional significance and future directions. Progress in Brain Research. 100: 81-6. PMID 7938538 DOI: 10.1016/S0079-6123(08)60772-4  0.526
1994 Mansour A, Fox CA, Burke S, Meng F, Thompson RC, Akil H, Watson SJ. Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study. The Journal of Comparative Neurology. 350: 412-38. PMID 7884049 DOI: 10.1002/cne.903500307  0.572
1994 Meng F, Xie GX, Chalmers D, Morgan C, Watson SJ, Akil H. Cloning and characterization of a pharmacologically distinct A1 adenosine receptor from guinea pig brain. Brain Research. Molecular Brain Research. 26: 143-55. PMID 7854041 DOI: 10.1016/0169-328X(94)90085-X  0.519
1994 Caamaño CA, Morano MI, Watson SJ, Dalman FC, Pratt WB, Akil H. The functional relevance of the heteromeric structure of corticosteroid receptors. Annals of the New York Academy of Sciences. 746: 68-77; discussion 77. PMID 7825922 DOI: 10.1111/J.1749-6632.1994.Tb39213.X  0.492
1994 Herman JP, Watson SJ. Glucocorticoid regulation of stress-induced mineralocorticoid receptor gene transcription in vivo. Annals of the New York Academy of Sciences. 746: 485-8. PMID 7825921 DOI: 10.1111/J.1749-6632.1994.Tb39292.X  0.49
1994 Ruzicka BB, Fox CA, Thompson RC, Akil H, Watson SJ. Opioid receptor mRNA expression in primary cultures of glial cells derived from different rat brain regions Regulatory Peptides. 54: 251-252. DOI: 10.1016/0167-0115(94)90484-7  0.578
1994 Mansour A, Fox C, Burke S, Watson S. Immunohistochemical localization of the kappa1 opioid receptors Regulatory Peptides. 54: 177-178. DOI: 10.1016/0167-0115(94)90448-0  0.371
1994 Fox CA, Mansour A, Ruzicka BB, Akil H, Watson SJ. The effects of haloperidol on μ, δ and κ opioid receptor mRNA expression in the striatum Regulatory Peptides. 54: 95-96. DOI: 10.1016/0167-0115(94)90406-5  0.555
1994 Fickel J, Xie G, Thompson R, Watson S, Akil H. Cloning of potential candidates for guinea pig opioid receptors Regulatory Peptides. 54: 93-94. DOI: 10.1016/0167-0115(94)90405-7  0.547
1994 Akil H, Meng F, Thompson R, Mansour A, Xie G, Watson S. Molecular studies of multiple opioid receptors: Cloning, anatomical distribution, pharmacological profile Regulatory Peptides. 53: S9-S10. DOI: 10.1016/0167-0115(94)90215-1  0.538
1994 Young E, Murphy-Weinberg V, Lopez J, Watson S, Akil H. Normal response to AM metyrapone administration in depressed patients Biological Psychiatry. 35: 711. DOI: 10.1016/0006-3223(94)91002-2  0.496
1993 Vázquez DM, Morano MI, López JF, Watson SJ, Akil H. Short-term adrenalectomy increases glucocorticoid and mineralocorticoid receptor mRNA in selective areas of the developing hippocampus. Molecular and Cellular Neurosciences. 4: 455-71. PMID 19912953 DOI: 10.1006/Mcne.1993.1057  0.532
1993 Herman JP, Watson SJ, Chao HM, Coirini H, McEwen BS. Diurnal Regulation of Glucocorticoid Receptor and Mineralocorticoid Receptor mRNAs in Rat Hippocampus. Molecular and Cellular Neurosciences. 4: 181-90. PMID 19912921 DOI: 10.1006/Mcne.1993.1022  0.48
1993 Young EA, Kotun J, Haskett RF, Grunhaus L, Greden JF, Watson SJ, Akil H. Dissociation between pituitary and adrenal suppression to dexamethasone in depression. Archives of General Psychiatry. 50: 395-403. PMID 8489328 DOI: 10.1001/Archpsyc.1993.01820170073010  0.509
1993 Young EA, Przewlocki R, Patel P, Watson SJ, Akil H. Altered ratios of beta-endorphin: beta-lipotropin released from anterior lobe corticotropes with increased secretory drive. I. Effects of diminished glucocorticoid secretion. Journal of Neuroendocrinology. 5: 115-20. PMID 8485540 DOI: 10.1111/J.1365-2826.1993.Tb00370.X  0.503
1993 Chalmers DT, Kwak SP, Mansour A, Akil H, Watson SJ. Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 914-23. PMID 8441016 DOI: 10.1523/Jneurosci.13-03-00914.1993  0.604
1993 Kwak SP, Patel PD, Thompson RC, Akil H, Watson SJ. 5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus. Endocrinology. 133: 2344-50. PMID 8404687 DOI: 10.1210/endo.133.5.8404687  0.553
1993 Caamaño CA, Morano MI, Patel PD, Watson SJ, Akil H. A bacterially expressed mineralocorticoid receptor is associated in vitro with the 90-kilodalton heat shock protein and shows typical hormone- and DNA-binding characteristics. Biochemistry. 32: 8589-95. PMID 8395210  0.504
1993 Young EA, Watson SJ, Haskett RF, Akil H. β-Endorphin Responsiveness in Depression-Reply Archives of General Psychiatry. 50: 406-407. PMID 8387766 DOI: 10.1001/archpsyc.1993.01820170092012  0.476
1993 Young EA, Day R, Schafer M, Watson SJ, Akil H. Altered ratios of beta-endorphin:beta-lipotropin released from anterior lobe corticotropes with increased secretory drive. II. Repeated stress. Journal of Neuroendocrinology. 5: 121-6. PMID 8387374 DOI: 10.1111/j.1365-2826.1993.tb00371.x  0.515
1993 Kwak SP, Morano MI, Young EA, Watson SJ, Akil H. Diurnal CRH mRNA rhythm in the hypothalamus: decreased expression in the evening is not dependent on endogenous glucocorticoids. Neuroendocrinology. 57: 96-105. PMID 8386819 DOI: 10.1159/000126347  0.546
1993 Akil H, Haskett RF, Young EA, Grunhaus L, Kotun J, Weinberg V, Greden J, Watson SJ. Multiple HPA profiles in endogenous depression: effect of age and sex on cortisol and beta-endorphin. Biological Psychiatry. 33: 73-85. PMID 8382535 DOI: 10.1016/0006-3223(93)90305-W  0.491
1993 Thompson RC, Mansour A, Akil H, Watson SJ. Cloning and pharmacological characterization of a rat mu opioid receptor. Neuron. 11: 903-13. PMID 8240812 DOI: 10.1016/0896-6273(93)90120-G  0.567
1993 Meng F, Xie GX, Thompson RC, Mansour A, Goldstein A, Watson SJ, Akil H. Cloning and pharmacological characterization of a rat kappa opioid receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 9954-8. PMID 8234341 DOI: 10.1073/Pnas.90.21.9954  0.558
1993 Mansour A, Thompson RC, Akil H, Watson SJ. Delta opioid receptor mRNA distribution in the brain: comparison to delta receptor binding and proenkephalin mRNA. Journal of Chemical Neuroanatomy. 6: 351-62. PMID 8142072 DOI: 10.1016/0891-0618(93)90010-2  0.555
1993 Cullinan WE, Herman JP, Watson SJ. Ventral subicular interaction with the hypothalamic paraventricular nucleus: evidence for a relay in the bed nucleus of the stria terminalis. The Journal of Comparative Neurology. 332: 1-20. PMID 7685778 DOI: 10.1002/Cne.903320102  0.441
1993 López JF, Palkovits M, Arató M, Mansour A, Akil H, Watson SJ. Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims. Neuroendocrinology. 56: 491-501. PMID 1335553 DOI: 10.1159/000126266  0.552
1992 Kwak SP, Young EA, Akil H, Watson SJ. Changes in proopiomelanocortin primary transcript levels in the anterior pituitary accompany increased adrenocorticotropin secretion during the diurnal surge. Journal of Neuroendocrinology. 4: 21-8. PMID 21554572 DOI: 10.1111/j.1365-2826.1992.tb00340.x  0.531
1992 Mansour A, Meador-Woodruff JH, Zhou Q, Civelli O, Akil H, Watson SJ. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 46: 959-71. PMID 1531866 DOI: 10.1016/0306-4522(92)90197-A  0.549
1992 Bronstein DM, Schafer MKH, Watson SJ, Akil H. Evidence that β-endorphin is synthesized in cells in the nucleus tractus solitarius: detection of POMC mRNA Brain Research. 587: 269-275. PMID 1525660 DOI: 10.1016/0006-8993(92)91007-2  0.556
1992 Herman JP, Cullinan WE, Young EA, Akil H, Watson SJ. Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression. Brain Research. 592: 228-38. PMID 1333341 DOI: 10.1016/0006-8993(92)91680-D  0.639
1992 Herman JP, Schafer MK, Thompson RC, Watson SJ. Rapid regulation of corticotropin-releasing hormone gene transcription in vivo. Molecular Endocrinology (Baltimore, Md.). 6: 1061-9. PMID 1324419 DOI: 10.1210/Mend.6.7.1324419  0.488
1992 Kwak SP, Young EA, Morano I, Watson SJ, Akil H. Diurnal corticotropin-releasing hormone mRNA variation in the hypothalamus exhibits a rhythm distinct from that of plasma corticosterone. Neuroendocrinology. 55: 74-83. PMID 1319007 DOI: 10.1159/000126099  0.554
1991 Young EA, Grunhaus L, Haskett RF, Pande AC, Murphy-Weinberg V, Akil H, Watson SJ. Heterogeneity in the beta-endorphin immunoreactivity response to electroconvulsive therapy. Archives of General Psychiatry. 48: 534-9. PMID 2039337 DOI: 10.1001/ARCHPSYC.1991.01810300046006  0.496
1991 Day R, Schafer MK, Collard MW, Watson SJ, Akil H. Atypical prodynorphin gene expression in corticosteroid-producing cells of the rat adrenal gland. Proceedings of the National Academy of Sciences of the United States of America. 88: 1320-4. PMID 1996333 DOI: 10.1073/PNAS.88.4.1320  0.577
1991 Ford-Holevinski TS, Castle MR, Herman JP, Watson SJ. Microcomputer-based three-dimensional reconstruction of in situ hybridization autoradiographs. Journal of Chemical Neuroanatomy. 4: 373-85. PMID 1958322 DOI: 10.1016/0891-0618(91)90044-D  0.41
1991 Cullinan WE, Day NC, Schäfer MK, Day R, Seidah NG, Chrétien M, Akil H, Watson SJ. Neuroanatomical and functional studies of peptide precursor-processing enzymes. Enzyme. 45: 285-300. PMID 1843282 DOI: 10.1159/000468902  0.541
1991 Herman JP, Schäfer MK, Watson SJ, Sherman TG. In situ hybridization analysis of arginine vasopressin gene transcription using intron-specific probes. Molecular Endocrinology (Baltimore, Md.). 5: 1447-56. PMID 1775130 DOI: 10.1210/Mend-5-10-1447  0.476
1991 Mansour A, Meador-Woodruff JH, Zhou QY, Civelli O, Akil H, Watson SJ. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 45: 359-71. PMID 1762683 DOI: 10.1016/0306-4522(91)90233-E  0.539
1991 Young EA, Haskett RF, Murphy-Weinberg V, Watson SJ, Akil H. Loss of glucocorticoid fast feedback in depression. Archives of General Psychiatry. 48: 693-9. PMID 1652926 DOI: 10.1001/ARCHPSYC.1991.01810320017003  0.516
1990 Herman JP, Wiegand SJ, Watson SJ. Regulation of basal corticotropin-releasing hormone and arginine vasopressin messenger ribonucleic acid expression in the paraventricular nucleus: effects of selective hypothalamic deafferentations. Endocrinology. 127: 2408-17. PMID 2171915 DOI: 10.1210/Endo-127-5-2408  0.49
1990 Mansour A, Meador-Woodruff JH, Bunzow JR, Civelli O, Akil H, Watson SJ. Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2587-600. PMID 2143777 DOI: 10.1523/Jneurosci.10-08-02587.1990  0.545
1990 Young EA, Watson SJ, Kotun J, Haskett RF, Grunhaus L, Murphy-Weinberg V, Vale W, Rivier J, Akil H. Beta-lipotropin-beta-endorphin response to low-dose ovine corticotropin releasing factor in endogenous depression. Preliminary studies. Archives of General Psychiatry. 47: 449-57. PMID 2139563 DOI: 10.1001/ARCHPSYC.1990.01810170049008  0.512
1990 Schäfer MK, Day R, Ortega MR, Akil H, Watson SJ. Proenkephalin messenger RNA is expressed both in the rat anterior and posterior pituitary. Neuroendocrinology. 51: 444-8. PMID 1693179 DOI: 10.1159/000125372  0.562
1989 Herman JP, Schäfer KH, Sladek CD, Day R, Young EA, Akil H, Watson SJ. Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP mRNA in select populations of neuroendocrine neurons. Brain Research. 501: 235-46. PMID 2819439 DOI: 10.1016/0006-8993(89)90641-0  0.66
1989 Herman JP, Patel PD, Akil H, Watson SJ. Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Molecular Endocrinology (Baltimore, Md.). 3: 1886-94. PMID 2558306 DOI: 10.1210/Mend-3-11-1886  0.632
1989 Meador-Woodruff JH, Silk KR, Kronfol Z, Watson SJ, Akil H. Gamma-melanotropin and beta-endorphin after dexamethasone. Biological Psychiatry. 25: 975-6. PMID 2541805 DOI: 10.1016/0006-3223(89)90278-3  0.467
1989 Minth CD, Qiu H, Akil H, Watson SJ, Dixon JE. Two precursors of melanin-concentrating hormone: DNA sequence analysis and in situ immunochemical localization. Proceedings of the National Academy of Sciences of the United States of America. 86: 4292-6. PMID 2471200 DOI: 10.1073/Pnas.86.11.4292  0.508
1988 Sherman TG, Day R, Civelli O, Douglass J, Herbert E, Akil H, Watson SJ. Regulation of hypothalamic magnocellular neuropeptides and their mRNAs in the Brattleboro rat: coordinate responses to further osmotic challenge. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3785-96. PMID 2903913 DOI: 10.1523/Jneurosci.08-10-03785.1988  0.612
1988 Watson SJ, Lopez JF, Young EA, Vale W, Rivier J, Akil H. Effects of low dose ovine corticotropin-releasing hormone in humans: endocrine relationships and beta-endorphin/beta-lipotropin responses. The Journal of Clinical Endocrinology and Metabolism. 66: 10-5. PMID 2826522 DOI: 10.1210/jcem-66-1-10  0.492
1988 Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ. Anatomy of CNS opioid receptors. Trends in Neurosciences. 11: 308-14. PMID 2465635 DOI: 10.1016/0166-2236(88)90093-8  0.547
1987 Meador-Woodruff JH, Watson SJ, Murphy-Weinberg V, Jegou S, Vaudry H, Seidah NG, Rivier J, Vale W, Akil H. Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans. Neuropeptides. 9: 269-82. PMID 3497356 DOI: 10.1016/0143-4179(87)90002-3  0.498
1987 Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ. Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 2445-64. PMID 3039080 DOI: 10.1016/0304-3959(88)90103-0  0.561
1987 Lewis J, Mansour A, Khachaturian H, Watson SJ, Akil H. Opioids and pain regulation. Pain and Headache. 9: 129-59. PMID 2825156  0.476
1987 Herman JP, Watson SJ. The rat brain in stereotaxic coordinates (2nd edn) Trends in Neurosciences. 10: 439. DOI: 10.1016/0166-2236(87)90017-8  0.434
1986 Khachaturian H, Akil H, Brownstein MJ, Olney JW, Voigt KH, Watson SJ. Further characterization of the extra-arcuate alpha-melanocyte stimulating hormone-like material in hypothalamus: biochemical and anatomical studies. Neuropeptides. 7: 291-313. PMID 3713997 DOI: 10.1016/0143-4179(86)90023-5  0.513
1986 Lewis ME, Sherman TG, Burke S, Akil H, Davis LG, Arentzen R, Watson SJ. Detection of proopiomelanocortin mRNA by in situ hybridization with an oligonucleotide probe. Proceedings of the National Academy of Sciences of the United States of America. 83: 5419-23. PMID 3461440 DOI: 10.1073/PNAS.83.15.5419  0.521
1986 Khachaturian H, Sherman TG, Lloyd RV, Civelli O, Douglass J, Herbert E, Akil H, Watson SJ. Pro-dynorphin is endogenous to the anterior pituitary and is co-localized with LH and FSH in the gonadotrophs. Endocrinology. 119: 1409-11. PMID 3089769 DOI: 10.1210/Endo-119-3-1409  0.529
1986 Mansour A, Lewis ME, Khachaturian H, Akil H, Watson SJ. Pharmacological and anatomical evidence of selective mu, delta, and kappa opioid receptor binding in rat brain. Brain Research. 399: 69-79. PMID 3026574 DOI: 10.1016/0006-8993(86)90601-3  0.535
1986 Young EA, Watson SJ, Akil H. Pituitary regulation in endogenous depression. Progress in Brain Research. 65: 153-66. PMID 3024222 DOI: 10.1016/S0079-6123(08)60648-2  0.527
1986 Shiomi H, Watson SJ, Kelsey JE, Akil H. Pretranslational and posttranslational mechanisms for regulating beta-endorphin-adrenocorticotropin of the anterior pituitary lobe. Endocrinology. 119: 1793-9. PMID 3019643 DOI: 10.1210/endo-119-4-1793  0.52
1986 Tsou K, Khachaturian H, Akil H, Watson SJ. Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord. Brain Research. 378: 28-35. PMID 3017502 DOI: 10.1016/0006-8993(86)90283-0  0.496
1986 Akil H, Young E, Walker JM, Watson SJ. The many possible roles of opioids and related peptides in stress-induced analgesia. Annals of the New York Academy of Sciences. 467: 140-53. PMID 2942087 DOI: 10.1111/J.1749-6632.1986.Tb14625.X  0.507
1986 Matthews J, Akil H, Greden J, Charney D, Weinberg V, Rosenbaum A, Watson SJ. beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone. Archives of General Psychiatry. 43: 374-81. PMID 2937385 DOI: 10.1001/Archpsyc.1986.01800040084012  0.514
1986 Saper CB, Akil H, Watson SJ. Lateral hypothalamic innervation of the cerebral cortex: immunoreactive staining for a peptide resembling but immunochemically distinct from pituitary/arcuate alpha-melanocyte stimulating hormone. Brain Research Bulletin. 16: 107-20. PMID 2420417 DOI: 10.1016/0361-9230(86)90018-3  0.512
1986 Kelsey J, Watson S, Burke S, Akil H, Roberts J. Characterization of proopiomelanocortin mRNA detected by in situ hybridization The Journal of Neuroscience. 6: 38-42. DOI: 10.1523/JNEUROSCI.06-01-00038.1986  0.53
1985 Khachaturian H, Lewis ME, Haber SN, Houghten RA, Akil H, Watson SJ. Prodynorphin peptide immunocytochemistry in rhesus monkey brain. Peptides. 6: 155-66. PMID 3909123 DOI: 10.1016/0196-9781(85)90149-4  0.546
1985 Dores RM, Lewis ME, Khachaturian H, Watson SJ, Akil H. Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat. Neuropeptides. 5: 501-4. PMID 2860608 DOI: 10.1016/0143-4179(85)90064-2  0.532
1984 Akil H, Lin HL, Ueda Y, Knobloch M, Watson SJ, Coy D. Some of the alpha-NH2-acetylated beta-endorphin-like material in rat and monkey pituitary and brain is acetylated alpha- and beta-endorphin. Life Sciences. 9-12. PMID 6664257 DOI: 10.1016/0024-3205(83)90431-9  0.491
1984 Lewis ME, Khachaturian H, Akil H, Watson SJ. Anatomical relationship between opioid peptides and receptors in rhesus monkey brain. Brain Research Bulletin. 13: 801-12. PMID 6152404 DOI: 10.1016/0361-9230(84)90238-7  0.54
1984 Lewis ME, Young EA, Houghten RA, Akil H, Watson SJ. Binding of [3H]dynorphin A to apparent kappa opioid receptors in deep layers of guinea pig cerebral cortex. European Journal of Pharmacology. 98: 149-50. PMID 6143673 DOI: 10.1016/0014-2999(84)90124-9  0.501
1984 Khachaturian H, Lewis ME, Haber SN, Akil H, Watson SJ. Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain. Brain Research Bulletin. 13: 785-800. PMID 6099745 DOI: 10.1016/0361-9230(84)90237-5  0.531
1984 Dores RM, Khachaturian H, Watson SJ, Akil H. Localization of neurons containing pro-opiomelanocortin-related peptides in the hypothalamus and midbrain of the lizard, Anolis carolinensis: evidence for region-specific processing of beta-endorphin. Brain Research. 324: 384-9. PMID 6099207 DOI: 10.1016/0006-8993(84)90055-6  0.533
1984 Khachaturian H, Dores RM, Watson SJ, Akil H. Beta-endorphin/ACTH immunocytochemistry in the CNS of the lizard Anolis carolinensis: evidence for a major mesencephalic cell group. The Journal of Comparative Neurology. 229: 576-84. PMID 6094619 DOI: 10.1002/cne.902290410  0.533
1984 Dores RM, Akil H, Watson SJ. Strategies for studying opioid peptide regulation at the gene, message and protein levels Peptides. 5: 9-17. PMID 6091069 DOI: 10.1016/0196-9781(84)90260-2  0.53
1983 Khachaturian H, Lewis ME, Hollt V, Watson SJ. Telencephalic enkephalinergic systems in the rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 844-55. PMID 6834107 DOI: 10.1523/Jneurosci.03-04-00844.1983  0.341
1983 Cahill C, Watson SJ, Knobloch M, Akil H. POMC in rhesus anterior pituitary and plasma: evidence of N-acetylated beta-endorphin and alpha-MSH. Life Sciences. 33: 53-5. PMID 6664235 DOI: 10.1016/0024-3205(83)90442-3  0.518
1983 Alessi NE, Khachaturian H, Watson S, Akil H. Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary. Life Sciences. 33: 57-60. PMID 6319911 DOI: 10.1016/0024-3205(83)90443-5  0.475
1983 Matthews J, Akil H, Greden J, Watson S. Plasma measures of B-endorphin-like immunoreactivity in depressives and other psychiatric subjects. Life Sciences. 31: 1867-70. PMID 6296577 DOI: 10.1016/0024-3205(82)90230-2  0.495
1983 Watson SJ, Khachaturian H, Taylor L, Fischli W, Goldstein A, Akil H. Pro-dynorphin peptides are found in the same neurons throughout rat brain: immunocytochemical study. Proceedings of the National Academy of Sciences of the United States of America. 80: 891-4. PMID 6131416 DOI: 10.1073/Pnas.80.3.891  0.546
1983 Shiomi H, Akil H, Watson SJ. Relationship between stress-induced analgesia and the POMC/β-endorphin system in the pituitary: Changes in β-endor-phin biosynthesis in acutely and chronically stressed rats Japanese Journal of Pharmacology. 33: 296. DOI: 10.1016/s0021-5198(19)60545-7  0.501
1982 Berger PA, Akil H, Watson SJ, Barchas JD. Behavioral pharmacology of the endorphins. Annual Review of Medicine. 33: 397-415. PMID 6282180 DOI: 10.1146/annurev.me.33.020182.002145  0.605
1982 Akil H, Young E, Watson SJ, Coy DH. Opiate binding properties of naturally occurring N- and C-terminus modified beta-endorphins. Peptides. 2: 289-92. PMID 6272244 DOI: 10.1016/S0196-9781(81)80121-0  0.523
1982 Khachaturian H, Watson SJ, Lewis ME, Coy D, Goldstein A, Akil H. Dynorphin immunocytochemistry in the rat central nervous system. Peptides. 3: 941-54. PMID 6132365 DOI: 10.1016/0196-9781(82)90063-8  0.543
1982 Watson SJ, Khachaturian H, Coy D, Taylor L, Akil H. Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin. Life Sciences. 31: 1773-6. PMID 6130437 DOI: 10.1016/0024-3205(82)90207-7  0.501
1982 Watson SJ, Khachaturian H, Akil H, Coy DH, Goldstein A. Comparison of the distribution of dynorphin systems and enkephalin systems in brain. Science (New York, N.Y.). 218: 1134-6. PMID 6128790 DOI: 10.1126/Science.6128790  0.535
1982 Watson SJ, Akil H, Fischli W, Goldstein A, Zimmerman E, Nilaver G, Van Wimersma Greidanus TB. Dynorphin and vasopressin: Common localization in magnocellular neurons Science. 216: 85-87. PMID 6121376 DOI: 10.1126/SCIENCE.6121376  0.599
1981 Berger PA, Watson SJ, Akil H, Barchas JD. Clinical studies on the role of endorphins in schizophrenia. Modern Problems of Pharmacopsychiatry. 17: 226-35. PMID 6276727 DOI: 10.1159/000402418  0.583
1981 Berger PA, Watson SJ, Akil H, Barchas JD. The effects of naloxone in chronic schizophrenia. The American Journal of Psychiatry. 138: 913-8. PMID 6266259 DOI: 10.1176/AJP.138.7.913  0.636
1981 Watson SJ, Akil H, Ghazarossian VE, Goldstein A. Dynorphin immunocytochemical localization in brain and peripheral nervous system: Preliminary studies Proceedings of the National Academy of Sciences of the United States of America. 78: 1260-1263. PMID 6112743 DOI: 10.1073/PNAS.78.2.1260  0.541
1981 Walker JM, Akil H, Watson SJ. γ-Msh potentiates acth analgesia Pain. 11: S266. DOI: 10.1016/0304-3959(81)90531-5  0.473
1981 Akil H, Ueda Y, Lin H, Watson S. A sensitive coupled technique for separation of endorphins: Multiple forms of B-endorphin in rat pituitary intermediate vs. anterior lobe Neuropeptides. 1: 429-446. DOI: 10.1016/0143-4179(81)90041-X  0.527
1980 Berger PA, Watson SJ, Akil H, Elliott GR, Rubin RT, Pfefferbaum A, Davis KL, Barchas JD, Li CH. beta-Endorphin and schizophrenia. Archives of General Psychiatry. 37: 635-40. PMID 7387335 DOI: 10.1001/Archpsyc.1980.01780190033003  0.609
1980 Watson SJ, Richard CW, Ciaranello RD, Barchas JD. Interaction of opiate peptide and noradrenalin systems: light microscopic studies. Peptides. 1: 23-30. PMID 7017618 DOI: 10.1016/0196-9781(80)90031-5  0.441
1980 Watson SJ, Akil H. alpha-MSH in rat brain: occurrence within and outside of beta-endorphin neurons. Brain Research. 182: 217-23. PMID 6985811 DOI: 10.1016/0006-8993(80)90849-5  0.525
1980 Walker JM, Akil H, Watson SJ. Evidence for homologous actions of pro-opiocortin products. Science (New York, N.Y.). 210: 1247-9. PMID 6254152 DOI: 10.1126/Science.6254152  0.556
1980 Watson SJ, Akil H. The presence of two alpha-MSH positive cell groups in rat hypothalamus. European Journal of Pharmacology. 58: 101-3. PMID 387425 DOI: 10.1016/0014-2999(79)90351-0  0.497
1980 Watson SJ, Akil H, Michael Walker J. Anatomical and biochemical studies of the opioid peptides and related substances in the brain Peptides. 1: 11-20. DOI: 10.1016/0196-9781(80)90099-6  0.53
1979 Akil H, Watson SJ, Barchas JD, Li CH. B-ETA-Endorphin immunoreactivity in rat and human blood: radioimmunoassay, comparative levels and physiological alterations. Life Sciences. 24: 1659-65. PMID 225617 DOI: 10.1016/0024-3205(79)90250-9  0.617
1979 Watson SJ, Akil H, Berger PA, Barchas JD. Some observations on the opiate peptides and schizophrenia. Archives of General Psychiatry. 36: 35-41. PMID 216330 DOI: 10.1001/archpsyc.1979.01780010041004  0.614
1979 Watson SJ, Akil H. "Endorphins, Dopamine, and Schizophrenia": Two Discussions Schizophrenia Bulletin. 5: 240-242. DOI: 10.1093/SCHBUL/5.2.240  0.464
1979 Akil H, Watson SJ, Sullivan S, Barchas JD. Enkephalin-like material in normal human CSF: measurement and levels Pain. 6: 386-387. DOI: 10.1016/0304-3959(79)90063-0  0.599
1978 Watson SJ, Berger PA, Akil H, Mills MJ, Barchas JD. Effects of naloxone on schizophrenia: reduction in hallucinations in a subpopulation of subjects. Science (New York, N.Y.). 201: 73-6. PMID 351804 DOI: 10.1126/SCIENCE.351804  0.628
1978 Akil H, Watson SJ, Sullivan S, Barchas JD. Enkephalin-like material in normal human CSF: measurement and levels. Life Sciences. 23: 121-5. PMID 210344 DOI: 10.1016/0024-3205(78)90259-X  0.617
1978 Watson SJ, Richard CW, Barchas JD. Adrenocorticotropin in rat brain: immunocytochemical localization in cells and axons. Science (New York, N.Y.). 200: 1180-2. PMID 206967  0.452
1978 Barchas JD, Akil H, Elliott GR, Holman RB, Watson SJ. Behavioral neurochemistry: neuroregulators and behavioral states. Science (New York, N.Y.). 200: 964-73. PMID 25486 DOI: 10.1126/Science.25486  0.613
1977 Berger PA, Elliott GR, Erdelyi E, Watson SJ, Wyatt RJ, Barchas JD. Platelet methylene reductase activity in schizophrenia. Archives of General Psychiatry. 34: 808-9. PMID 879976 DOI: 10.1001/archpsyc.1977.01770190070006  0.397
1977 Watson SJ, Barchas JD. Catecholamine histofluorescence using cryostat sectioning and glyoxylic acid in unperfused frozen brain: a detailed description of the technique. The Histochemical Journal. 9: 183-95. PMID 838603  0.42
1977 Watson SJ, Barchas JD, Li CH. beta-Lipotropin: localization of cells and axons in rat brain by immunocytochemistry. Proceedings of the National Academy of Sciences of the United States of America. 74: 5155-8. PMID 337312  0.452
1977 Watson SJ, Akil H, Sullivan S, Barchas JD. Immunocytochemical localization of methionine enkephalin: preliminary observations. Life Sciences. 21: 733-8. PMID 333216 DOI: 10.1016/0024-3205(77)90083-2  0.625
1977 Watson SJ, Akil H, Barchas JD. A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study. Brain Research. 130: 335-42. PMID 195673 DOI: 10.1016/0006-8993(77)90279-7  0.62
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