Chris Gaiteri - Publications

Sage Bionetworks 
dynamical systems, gene networks

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, ... ... Gaiteri C, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.307
2021 Ng B, Casazza W, Kim NH, Wang C, Farhadi F, Tasaki S, Bennett DA, De Jager PL, Gaiteri C, Mostafavi S. Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants. Plos Genetics. 17: e1009918. PMID 34807913 DOI: 10.1371/journal.pgen.1009918  0.32
2021 Lagomarsino VN, Pearse RV, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, et al. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. PMID 34473944 DOI: 10.1016/j.neuron.2021.08.003  0.301
2021 Patrick E, Olah M, Taga M, Klein HU, Xu J, White CC, Felsky D, Agrawal S, Gaiteri C, Chibnik LB, Mostafavi S, Schneider JA, Bennett DA, Bradshaw EM, De Jager PL. A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies. Translational Psychiatry. 11: 50. PMID 33446646 DOI: 10.1038/s41398-020-01175-9  0.33
2020 Heuer SE, Neuner SM, Hadad N, O'Connell KMS, Williams RW, Philip VM, Gaiteri C, Kaczorowski CC. Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice. Learning & Memory (Cold Spring Harbor, N.Y.). 27: 355-371. PMID 32817302 DOI: 10.1101/Lm.051839.120  0.434
2020 Patrick E, Taga M, Ergun A, Ng B, Casazza W, Cimpean M, Yung C, Schneider JA, Bennett DA, Gaiteri C, De Jager PL, Bradshaw EM, Mostafavi S. Deconvolving the contributions of cell-type heterogeneity on cortical gene expression. Plos Computational Biology. 16: e1008120. PMID 32804935 DOI: 10.1371/Journal.Pcbi.1008120  0.337
2020 Tasaki S, Gaiteri C, Mostafavi S, Wang Y. Deep learning decodes the principles of differential gene expression. Nature Machine Intelligence. 2: 376-386. PMID 32671330 DOI: 10.1038/S42256-020-0201-6  0.358
2020 Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908  0.429
2020 Yang HS, White CC, Klein HU, Yu L, Gaiteri C, Ma Y, Felsky D, Mostafavi S, Petyuk VA, Sperling RA, Ertekin-Taner N, Schneider JA, Bennett DA, De Jager PL. Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. Neuron. PMID 32526197 DOI: 10.1016/J.Neuron.2020.05.010  0.438
2019 Tasaki S, Gaiteri C, Petyuk VA, Blizinsky KD, De Jager PL, Buchman AS, Bennett DA. Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults. Translational Psychiatry. 9: 241. PMID 31582723 DOI: 10.1038/S41398-019-0577-4  0.348
2019 Kim N, Yu L, Dawe R, Petyuk VA, Gaiteri C, De Jager PL, Schneider JA, Arfanakis K, Bennett DA. Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline. Neurobiology of Aging. 84: 17-25. PMID 31479860 DOI: 10.1016/J.Neurobiolaging.2019.07.013  0.333
2019 Ng B, Casazza W, Patrick E, Tasaki S, Novakovsky G, Felsky D, Ma Y, Bennett DA, Gaiteri C, De Jager PL, Mostafavi S. Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain. American Journal of Human Genetics. PMID 31447098 DOI: 10.1016/J.Ajhg.2019.07.016  0.411
2019 Buchman AS, Yu L, Petyuk VA, Gaiteri C, Tasaki S, Blizinsky KD, Schneider JA, De Jager PL, Bennett DA. Cognition may link cortical IGFBP5 levels with motor function in older adults. Plos One. 14: e0220968. PMID 31404102 DOI: 10.1371/Journal.Pone.0220968  0.337
2019 Buchman AS, Yu L, Wilson RS, Lim A, Dawe RJ, Gaiteri C, Leurgans SE, Schneider JA, Bennett DA. Physical activity, common brain pathologies, and cognition in community-dwelling older adults. Neurology. PMID 30651386 DOI: 10.1212/Wnl.0000000000006954  0.339
2019 Kaczorowski C, Heuer S, Gaiteri C, Kaczorowski C. MULTI-OMICS ANALYSIS IDENTIFIES GENE NETWORKS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER’S DISEASE Innovation in Aging. 3: S587-S588. DOI: 10.1093/Geroni/Igz038.2179  0.433
2019 Heuer SE, Neuner SM, Gaiteri C, Kaczorowski CC. O4-10-05: MULTI-OMIC ANALYSIS IDENTIFIES TRANSCRIPTIONAL NETWORKS AND DRIVERS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1260-P1261. DOI: 10.1016/J.Jalz.2019.06.4798  0.401
2018 Tasaki S, Gaiteri C, Mostafavi S, De Jager PL, Bennett DA. The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia. Frontiers in Neuroscience. 12: 699. PMID 30349450 DOI: 10.3389/Fnins.2018.00699  0.365
2018 Lamar M, Yu L, Rubin LH, James BD, Barnes LL, Farfel JM, Gaiteri C, Buchman AS, Bennett DA, Schneider JA. APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321502 DOI: 10.1016/J.Jalz.2018.08.007  0.361
2018 Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, et al. Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts. Plos Medicine. 15: e1002647. PMID 30180184 DOI: 10.1371/Journal.Pmed.1002647  0.357
2018 Tasaki S, Gaiteri C, Mostafavi S, Yu L, Wang Y, De Jager PL, Bennett DA. Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline. Frontiers in Genetics. 9: 294. PMID 30140277 DOI: 10.3389/Fgene.2018.00294  0.492
2018 De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, et al. A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research. Scientific Data. 5: 180142. PMID 30084846 DOI: 10.1038/Sdata.2018.142  0.331
2018 Felsky D, Patrick E, Schneider JA, Mostafavi S, Gaiteri C, Patsopoulos N, Bennett DA, De Jager PL. Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain. Molecular Neurodegeneration. 13: 38. PMID 30041668 DOI: 10.1186/S13024-018-0272-6  0.363
2018 Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics. Brain Imaging and Behavior. PMID 29934819 DOI: 10.1007/S11682-018-9910-4  0.441
2018 Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA. Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia. Annals of Neurology. PMID 29908079 DOI: 10.1002/Ana.25266  0.471
2018 Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, et al. A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease. Nature Neuroscience. 21: 811-819. PMID 29802388 DOI: 10.1038/S41593-018-0154-9  0.467
2018 Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA. ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. PMID 29752306 DOI: 10.1212/Wnl.0000000000005677  0.318
2018 Yang H, White CC, Klein H, Gaiteri C, Mostafavi S, Felsky D, Yu L, Sperling RA, Schneider JA, Bennett DA, Jager PLD. P3-136: Module Quantitative Trait Loci Analysis Implicates Tmem106B And Rbfox1 As Key Brain Transcriptome Regulators In Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1493  0.309
2017 Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. Jama Neurology. PMID 29084334 DOI: 10.1001/Jamaneurol.2017.2807  0.312
2017 Ng B, White CC, Klein HU, Sieberts SK, McCabe C, Patrick E, Xu J, Yu L, Gaiteri C, Bennett DA, Mostafavi S, De Jager PL. An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome. Nature Neuroscience. PMID 28869584 DOI: 10.1038/Nn.4632  0.342
2017 Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA. TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype. Neurology. PMID 28108637 DOI: 10.1212/Wnl.0000000000003614  0.375
2016 Gaiteri C, Mostafavi S, Honey CJ, De Jager PL, Bennett DA. Genetic variants in Alzheimer disease - molecular and brain network approaches. Nature Reviews. Neurology. PMID 27282653 DOI: 10.1038/Nrneurol.2016.84  0.366
2015 Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA. Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies. The International Journal of Biochemistry & Cell Biology. PMID 26003740 DOI: 10.1016/J.Biocel.2015.05.009  0.326
2015 Tasaki S, Sauerwine B, Hoff B, Toyoshiba H, Gaiteri C, Chaibub Neto E. Bayesian network reconstruction using systems genetics data: comparison of MCMC methods. Genetics. 199: 973-89. PMID 25631319 DOI: 10.1534/genetics.114.172619  0.411
2014 Nichols TW, Gaiteri C. Morton's foot and pyridoxal 5'-phosphate deficiency: genetically linked traits. Medical Hypotheses. 83: 644-8. PMID 25441836 DOI: 10.1016/j.mehy.2014.09.003  0.31
2014 Gaiteri C, Ding Y, French B, Tseng GC, Sibille E. Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders. Genes, Brain, and Behavior. 13: 13-24. PMID 24320616 DOI: 10.1111/Gbb.12106  0.631
2013 Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, et al. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell. 153: 707-20. PMID 23622250 DOI: 10.1016/J.Cell.2013.03.030  0.455
2013 Giraldo M, Lopera F, Siniard AL, Corneveaux JJ, Schrauwen I, Carvajal J, Muñoz C, Ramirez-Restrepo M, Gaiteri C, Myers AJ, Caselli RJ, Kosik KS, Reiman EM, Huentelman MJ. Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiology of Aging. 34: 2077.e11-8. PMID 23582655 DOI: 10.1016/J.Neurobiolaging.2013.02.016  0.366
2011 Gaiteri C, Sibille E. Differentially expressed genes in major depression reside on the periphery of resilient gene coexpression networks. Frontiers in Neuroscience. 5: 95. PMID 21922000 DOI: 10.3389/fnins.2011.00095  0.626
2011 Gaiteri C, Rubin JE. The interaction of intrinsic dynamics and network topology in determining network burst synchrony. Frontiers in Computational Neuroscience. 5: 10. PMID 21373358 DOI: 10.3389/Fncom.2011.00010  0.335
2010 Gaiteri C, Guilloux JP, Lewis DA, Sibille E. Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression. Plos One. 5: e9970. PMID 20376317 DOI: 10.1371/Journal.Pone.0009970  0.671
2010 Guilloux JP, Gaiteri C, Sibille E. Network analysis of positional candidate genes of schizophrenia highlights...more than... myelin-related pathways. Molecular Psychiatry. 15: 786-8. PMID 20351722 DOI: 10.1038/mp.2009.68  0.637
2009 Sibille E, Wang Y, Joeyen-Waldorf J, Gaiteri C, Surget A, Oh S, Belzung C, Tseng GC, Lewis DA. A molecular signature of depression in the amygdala. The American Journal of Psychiatry. 166: 1011-24. PMID 19605536 DOI: 10.1176/Appi.Ajp.2009.08121760  0.493
2007 Gaiteri C, Rubin J. How intrinsic dynamics and coupling architecture interact to generate bursting dynamics in a model network of respiratory conditional pacemakers Bmc Neuroscience. 8: 184. DOI: 10.1186/1471-2202-8-S2-P184  0.303
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