Kay Elizabeth Davies - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Muscular Dystrophy, Ataxia

342 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Meijboom KE, Sutton ER, McCallion E, McFall E, Anthony D, Edwards B, Kubinski S, Tapken I, Bünermann I, Hazell G, Ahlskog N, Claus P, Davies KE, Kothary R, Wood MJA, et al. Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice. Skeletal Muscle. 12: 18. PMID 35902978 DOI: 10.1186/s13395-022-00301-z  0.459
2021 Ang G, Brown LA, Tam SKE, Davies KE, Foster RG, Harrison PJ, Sprengel R, Vyazovskiy VV, Oliver PL, Bannerman DM, Peirson SN. Deletion of AMPA receptor GluA1 subunit gene (Gria1) causes circadian rhythm disruption and aberrant responses to environmental cues. Translational Psychiatry. 11: 588. PMID 34782594 DOI: 10.1038/s41398-021-01690-3  0.723
2021 Vuorinen A, Wilkinson IVL, Chatzopoulou M, Edwards B, Squire SE, Fairclough RJ, Bazan NA, Milner JA, Conole D, Donald JR, Shah N, Willis NJ, Martínez RF, Wilson FX, Wynne GM, ... ... Davies KE, et al. Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. European Journal of Medicinal Chemistry. 220: 113431. PMID 33915371 DOI: 10.1016/j.ejmech.2021.113431  0.591
2020 Lovering RM, Iyer SR, Edwards B, Davies KE. Alterations of neuromuscular junctions in Duchenne muscular dystrophy. Neuroscience Letters. 135304. PMID 32818587 DOI: 10.1016/J.Neulet.2020.135304  0.509
2020 Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Figuccia ALA, Fletcher AM, Guiraud S, Harriman S, Moir L, Robinson N, Rowley JA, et al. Synthesis of SMT022357 enantiomers and evaluation in a Duchenne muscular dystrophy mouse model. Tetrahedron. 76: 130819. PMID 32713969 DOI: 10.1016/J.Tet.2019.130819  0.474
2020 Babbs A, Chatzopoulou M, Edwards B, Squire SE, Wilkinson IVL, Wynne GM, Russell AJ, Davies KE. From diagnosis to therapy in Duchenne muscular dystrophy. Biochemical Society Transactions. PMID 32597486 DOI: 10.1042/Bst20190282  0.356
2020 Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey D, Emer E, Guiraud S, Harriman S, Lecci C, Moir L, Peters D, Robinson N, Rowley J, et al. 2-Arylbenzo[d]oxazole phosphinate esters as second-generation modulators of utrophin for the treatment of Duchenne Muscular Dystrophy. Journal of Medicinal Chemistry. PMID 32551645 DOI: 10.1021/Acs.Jmedchem.0C00807  0.489
2019 Wilkinson IVL, Perkins KJ, Dugdale H, Moir L, Vuorinen A, Chatzopoulou M, Squire SE, Monecke S, Lomow A, Geese M, Charles PD, Burch P, Tinsley JM, Wynne GM, Davies SG, ... ... Davies KE, et al. Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid. Angewandte Chemie (International Ed. in English). PMID 31755636 DOI: 10.1002/Anie.201912392  0.342
2019 Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics. PMID 31642482 DOI: 10.1093/Hmg/Ddz190  0.805
2019 Davies KE, Chamberlain JS. Surrogate gene therapy for muscular dystrophy. Nature Medicine. PMID 31591598 DOI: 10.1038/s41591-019-0604-2  0.324
2019 Pomatto LCD, Sun PY, Yu K, Gullapalli S, Bwiza CP, Sisliyan C, Wong S, Zhang H, Forman HJ, Oliver PL, Davies KE, Davies KJA. Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing. Redox Biology. 24: 101194. PMID 31022673 DOI: 10.1016/J.Redox.2019.101194  0.729
2019 Guiraud S, Edwards B, Babbs A, Squire SE, Berg A, Moir L, Wood MJ, Davies KE. The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy. Human Molecular Genetics. PMID 30990876 DOI: 10.1093/Hmg/Ddz049  0.528
2019 Guiraud S, Davies KE. Regenerative biomarkers for Duchenne muscular dystrophy. Neural Regeneration Research. 14: 1317-1320. PMID 30964048 DOI: 10.4103/1673-5374.253534  0.322
2018 Kennedy TL, Guiraud S, Edwards B, Squire S, Moir L, Babbs A, Odom G, Golebiowski D, Schneider J, Chamberlain JS, Davies KE. Micro-utrophin Improves Cardiac and Skeletal Muscle Function of Severely Affected D2/ Mice. Molecular Therapy. Methods & Clinical Development. 11: 92-105. PMID 30417024 DOI: 10.1016/J.Omtm.2018.10.005  0.349
2018 Guiraud S, Edwards B, Squire SE, Moir L, Berg A, Babbs A, Ramadan N, Wood MJ, Davies KE. Embryonic myosin is a regeneration marker to monitor utrophin based therapies for DMD. Human Molecular Genetics. PMID 30304405 DOI: 10.1093/Hmg/Ddy353  0.529
2018 Ang G, McKillop LE, Purple R, Blanco-Duque C, Peirson SN, Foster RG, Harrison PJ, Sprengel R, Davies KE, Oliver PL, Bannerman DM, Vyazovskiy VV. Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders. Translational Psychiatry. 8: 154. PMID 30108203 DOI: 10.1038/S41398-018-0199-2  0.722
2018 Perkins KJ, Davies KE. Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy. Febs Letters. PMID 29772070 DOI: 10.1002/1873-3468.13099  0.347
2017 Kennedy TL, Moir L, Hemming S, Edwards B, Squire S, Davies K, Guiraud S. Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle. Skeletal Muscle. 7: 22. PMID 29065908 DOI: 10.1186/S13395-017-0139-5  0.306
2017 Guiraud S, Davies KE. Pharmacological advances for treatment in Duchenne muscular dystrophy. Current Opinion in Pharmacology. 34: 36-48. PMID 28486179 DOI: 10.1016/j.coph.2017.04.002  0.332
2017 Guiraud S, Edwards B, Squire SE, Babbs A, Shah N, Berg A, Chen H, Davies KE. Identification of serum protein biomarkers for utrophin based DMD therapy. Scientific Reports. 7: 43697. PMID 28252048 DOI: 10.1016/J.Nmd.2017.06.269  0.534
2016 Wu Y, Davies KE, Oliver PL. The antioxidant protein Oxr1 influences aspects of mitochondrial morphology. Free Radical Biology & Medicine. PMID 27036366 DOI: 10.1016/J.Freeradbiomed.2016.03.029  0.745
2015 Finelli MJ, Sanchez-Pulido L, Liu KX, Davies KE, Oliver PL. The evolutionarily conserved Tre2/Bub2/Cdc16 (TBC), Lysin motif (LysM), Domain catalytic (TLDc) domain is neuroprotective against oxidative stress. The Journal of Biological Chemistry. PMID 26668325 DOI: 10.1074/Jbc.M115.685222  0.784
2015 Pembroke WG, Babbs A, Davies K, Ponting CP, Oliver PL. Temporal transcriptomics suggest that twin-peaking genes reset the clock. Elife. 4. PMID 26523393 DOI: 10.7554/Elife.10518  0.744
2015 Richardson K, Livieratos A, Dumbill R, Hughes S, Ang G, Smith DA, Morris L, Brown LA, Peirson SN, Platt FM, Davies KE, Oliver PL. Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease. Behavioural Brain Research. 297: 213-223. PMID 26467605 DOI: 10.1016/J.Bbr.2015.10.021  0.759
2015 Guiraud S, Chen H, Burns DT, Davies KE. Advances in genetic therapeutic strategies for Duchenne muscular dystrophy. Experimental Physiology. PMID 26140505 DOI: 10.1113/EP085308  0.389
2015 Guiraud S, Aartsma-Rus A, Vieira NM, Davies KE, van Ommen GJ, Kunkel LM. The Pathogenesis and Therapy of Muscular Dystrophies. Annual Review of Genomics and Human Genetics. PMID 26048046 DOI: 10.1146/annurev-genom-090314-025003  0.403
2015 Guiraud S, Squire SE, Edwards B, Chen H, Burns DT, Shah N, Babbs A, Davies SG, Wynne GM, Russell AJ, Elsey D, Wilson FX, Tinsley JM, Davies KE. Second-generation compound for the modulation of utrophin in the therapy of DMD. Human Molecular Genetics. 24: 4212-24. PMID 25935002 DOI: 10.1093/Hmg/Ddv154  0.537
2015 Dulneva A, Lee S, Oliver PL, Di Gleria K, Kessler BM, Davies KE, Becker EB. The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum. Human Molecular Genetics. 24: 4114-25. PMID 25908616 DOI: 10.1093/Hmg/Ddv150  0.775
2015 Finelli MJ, Liu KX, Wu Y, Oliver PL, Davies KE. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations. Human Molecular Genetics. 24: 3529-44. PMID 25792726 DOI: 10.1093/Hmg/Ddv104  0.802
2015 Liu KX, Edwards B, Lee S, Finelli MJ, Davies B, Davies KE, Oliver PL. Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 138: 1167-81. PMID 25753484 DOI: 10.1093/Brain/Awv039  0.794
2015 Goyenvalle A, Griffith G, Babbs A, El Andaloussi S, Ezzat K, Avril A, Dugovic B, Chaussenot R, Ferry A, Voit T, Amthor H, Bühr C, Schürch S, Wood MJ, Davies KE, et al. Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers. Nature Medicine. 21: 270-5. PMID 25642938 DOI: 10.1038/Nm.3765  0.37
2015 Pembroke WG, Babbs A, Davies KE, Ponting CP, Oliver PL. Author response: Temporal transcriptomics suggest that twin-peaking genes reset the clock Elife. DOI: 10.7554/Elife.10518.033  0.728
2015 Araujo N, Vuorinen A, Fairclough R, Guiraud S, Donald J, Cairnduff C, Hewings D, Martinez F, Csatayova K, Willis N, Squire S, Babbs A, Edwards B, Shah N, Tinsley J, ... ... Davies K, et al. Discovery of small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 25: S260. DOI: 10.1016/J.Nmd.2015.06.272  0.579
2015 Tinsley J, Janghra N, Morgan J, Sewry C, Muntoni F, Elsey D, Wilson F, Davies K. Biomarker development to support the clinical development of utrophin modulators for Duchenne muscular dystrophy therapy Neuromuscular Disorders. 25: 826. DOI: 10.1016/J.Nmd.2015.06.241  0.309
2014 Moore JM, Oliver PL, Finelli MJ, Lee S, Lickiss T, Molnár Z, Davies KE. Laf4/Aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex. Plos One. 9: e105933. PMID 25162227 DOI: 10.1371/Journal.Pone.0105933  0.8
2014 Paton L, Bitoun E, Kenyon J, Priestman DA, Oliver PL, Edwards B, Platt FM, Davies KE. A novel mouse model of a patient mucolipidosis II mutation recapitulates disease pathology. The Journal of Biological Chemistry. 289: 26709-21. PMID 25107912 DOI: 10.1074/Jbc.M114.586156  0.81
2014 Turner BJ, Alfazema N, Sheean RK, Sleigh JN, Davies KE, Horne MK, Talbot K. Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice. Neurobiology of Aging. 35: 906-15. PMID 24210254 DOI: 10.1016/J.Neurobiolaging.2013.09.030  0.797
2014 Taylor TN, Potgieter D, Anwar S, Senior SL, Janezic S, Threlfell S, Ryan B, Parkkinen L, Deltheil T, Cioroch M, Livieratos A, Oliver PL, Jennings KA, Davies KE, Ansorge O, et al. Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse. Neurobiology of Disease. 62: 193-207. PMID 24121116 DOI: 10.1016/J.Nbd.2013.10.005  0.746
2014 Sleigh JN, Barreiro-Iglesias A, Oliver PL, Biba A, Becker T, Davies KE, Becker CG, Talbot K. Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. Human Molecular Genetics. 23: 855-69. PMID 24067532 DOI: 10.1093/Hmg/Ddt477  0.796
2014 Van Rossen E, Liu Z, Blijweert D, Eysackers N, Mannaerts I, Schroyen B, El Taghdouini A, Edwards B, Davies KE, Sokal E, Najimi M, Reynaert H, van Grunsven LA. Syncoilin is an intermediate filament protein in activated hepatic stellate cells. Histochemistry and Cell Biology. 141: 85-99. PMID 24043511 DOI: 10.1007/s00418-013-1142-5  0.513
2014 Fairclough R, Squire S, Araujo N, Vuorinen A, Davies S, Wynne G, Russell A, Davies K. P13 New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 24: S10. DOI: 10.1016/S0960-8966(14)70029-X  0.637
2014 Tinsley J, Bracchi A, Wilson F, Horne G, Robinson N, Fairclough R, Davies K. P10 Utrophin modulators to treat Duchenne Muscular Dystrophy (DMD): Future clinical trial plans for SMT C1100 and biomarker development programme Neuromuscular Disorders. 24: S9. DOI: 10.1016/S0960-8966(14)70026-4  0.575
2014 Fairclough R, Guiraud S, Squire S, Babbs A, Edward B, Shah N, Bracchi A, Wilson F, Horne G, Robinson N, Araujo N, Hewings D, Vuorinen A, Davies S, Wynne G, ... ... Davies K, et al. G.P.89 Neuromuscular Disorders. 24: 821. DOI: 10.1016/J.Nmd.2014.06.103  0.638
2013 Ravenscroft G, McNamara E, Griffiths LM, Papadimitriou JM, Hardeman EC, Bakker AJ, Davies KE, Laing NG, Nowak KJ. Cardiac α-actin over-expression therapy in dominant ACTA1 disease. Human Molecular Genetics. 22: 3987-97. PMID 23736297 DOI: 10.1093/hmg/ddt252  0.339
2013 Fairclough RJ, Wood MJ, Davies KE. Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches. Nature Reviews. Genetics. 14: 373-8. PMID 23609411 DOI: 10.1038/Nrg3460  0.627
2013 Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, ... ... Davies KE, et al. Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 266-8. PMID 23369965 DOI: 10.1038/Mt.2013.4  0.325
2013 Sleigh JN, Grice SJ, Davies KE, Talbot K. Spinal muscular atrophy at the crossroads of basic science and therapy. Neuromuscular Disorders : Nmd. 23: 96. PMID 22981697 DOI: 10.1016/J.Nmd.2012.08.008  0.794
2013 Tinsley J, Robinson N, Wilson F, Horne G, Fairclough R, Davies K. P.13.14 Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD) Neuromuscular Disorders. 23: 813. DOI: 10.1016/J.Nmd.2013.06.608  0.616
2012 Eckenfelder A, Tordo J, Babbs A, Davies KE, Goyenvalle A, Danos O. The Cellular Processing Capacity Limits the Amounts of Chimeric U7 snRNA Available for Antisense Delivery. Molecular Therapy. Nucleic Acids. 1: e31. PMID 23344083 DOI: 10.1038/Mtna.2012.24  0.353
2012 Oliver PL, Davies KE. New insights into behaviour using mouse ENU mutagenesis. Human Molecular Genetics. 21: R72-81. PMID 22892373 DOI: 10.1093/Hmg/Dds318  0.779
2012 Fairclough RJ, Perkins KJ, Davies KE. Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy. Current Gene Therapy. 12: 206-44. PMID 22571500 DOI: 10.2174/156652312800840595  0.64
2012 Pritchett D, Wulff K, Oliver PL, Bannerman DM, Davies KE, Harrison PJ, Peirson SN, Foster RG. Evaluating the links between schizophrenia and sleep and circadian rhythm disruption. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 1061-75. PMID 22569850 DOI: 10.1007/S00702-012-0817-8  0.717
2012 Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS. Hsp72 preserves muscle function and slows progression of severe muscular dystrophy. Nature. 484: 394-8. PMID 22495301 DOI: 10.1038/nature10980  0.327
2012 Goyenvalle A, Babbs A, Wright J, Wilkins V, Powell D, Garcia L, Davies KE. Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping. Human Molecular Genetics. 21: 2559-71. PMID 22388933 DOI: 10.1093/hmg/dds082  0.387
2012 Goyenvalle A, Wright J, Babbs A, Wilkins V, Garcia L, Davies KE. Engineering multiple U7snRNA constructs to induce single and multiexon-skipping for Duchenne muscular dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1212-21. PMID 22354379 DOI: 10.1038/mt.2012.26  0.376
2012 Oliver PL, Sobczyk MV, Maywood ES, Edwards B, Lee S, Livieratos A, Oster H, Butler R, Godinho SI, Wulff K, Peirson SN, Fisher SP, Chesham JE, Smith JW, Hastings MH, ... Davies KE, et al. Disrupted circadian rhythms in a mouse model of schizophrenia. Current Biology : Cb. 22: 314-9. PMID 22264613 DOI: 10.1016/J.Cub.2011.12.051  0.773
2012 Tan SC, Carr CA, Yeoh KK, Schofield CJ, Davies KE, Clarke K. Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors. Molecular Biology Reports. 39: 4857-67. PMID 22065248 DOI: 10.1007/S11033-011-1281-5  0.322
2012 Fairclough R, Squire S, Potter A, Powell D, Davies S, Bataille C, Wynne G, Russell A, Davies K. O01 Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 22: S3. DOI: 10.1016/S0960-8966(12)00071-5  0.567
2012 Goyenvalle A, Babbs A, Avril A, Griffiths G, Dugovic B, Davies KE, Leumann C, Garcia L. Tricyclo-DNA: A promising chemistry for the synthesis of antisense molecules for splice-switching approaches in DMD Neuromuscular Disorders. 22: 907-907. DOI: 10.1016/J.Nmd.2012.06.340  0.341
2011 Ravenscroft G, Jackaman C, Sewry CA, McNamara E, Squire SE, Potter AC, Papadimitriou J, Griffiths LM, Bakker AJ, Davies KE, Laing NG, Nowak KJ. Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression. Plos One. 6: e28699. PMID 22174871 DOI: 10.1371/journal.pone.0028699  0.369
2011 Oliver PL, Finelli MJ, Edwards B, Bitoun E, Butts DL, Becker EB, Cheeseman MT, Davies B, Davies KE. Oxr1 is essential for protection against oxidative stress-induced neurodegeneration. Plos Genetics. 7: e1002338. PMID 22028674 DOI: 10.1371/Journal.Pgen.1002338  0.777
2011 Fairclough RJ, Bareja A, Davies KE. Progress in therapy for Duchenne muscular dystrophy. Experimental Physiology. 96: 1101-13. PMID 21804140 DOI: 10.1113/Expphysiol.2010.053025  0.647
2011 Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, ... ... Davies KE, et al. Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. Plos Genetics. 7: e1002145. PMID 21765815 DOI: 10.1371/Journal.Pgen.1002145  0.796
2011 Tinsley JM, Fairclough RJ, Storer R, Wilkes FJ, Potter AC, Squire SE, Powell DS, Cozzoli A, Capogrosso RF, Lambert A, Wilson FX, Wren SP, De Luca A, Davies KE. Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse. Plos One. 6: e19189. PMID 21573153 DOI: 10.1371/Journal.Pone.0019189  0.625
2011 Pichavant C, Aartsma-Rus A, Clemens PR, Davies KE, Dickson G, Takeda S, Wilton SD, Wolff JA, Wooddell CI, Xiao X, Tremblay JP. Current status of pharmaceutical and genetic therapeutic approaches to treat DMD. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 830-40. PMID 21468001 DOI: 10.1038/Mt.2011.59  0.369
2011 Goyenvalle A, Seto JT, Davies KE, Chamberlain J. Therapeutic approaches to muscular dystrophy. Human Molecular Genetics. 20: R69-78. PMID 21436158 DOI: 10.1093/Hmg/Ddr105  0.367
2011 Becker EB, Fogel BL, Rajakulendran S, Dulneva A, Hanna MG, Perlman SL, Geschwind DH, Davies KE. Candidate screening of the TRPC3 gene in cerebellar ataxia. Cerebellum (London, England). 10: 296-9. PMID 21321808 DOI: 10.1007/S12311-011-0253-6  0.795
2011 Ravenscroft G, Jackaman C, Bringans S, Papadimitriou JM, Griffiths LM, McNamara E, Bakker AJ, Davies KE, Laing NG, Nowak KJ. Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies. Brain : a Journal of Neurology. 134: 1101-15. PMID 21303860 DOI: 10.1093/brain/awr004  0.385
2011 Goyenvalle A, Davies KE. Engineering exon-skipping vectors expressing U7 snRNA constructs for Duchenne muscular dystrophy gene therapy. Methods in Molecular Biology (Clifton, N.J.). 709: 179-96. PMID 21194028 DOI: 10.1007/978-1-61737-982-6_11  0.387
2011 Crisp A, Yin H, Goyenvalle A, Betts C, Moulton HM, Seow Y, Babbs A, Merritt T, Saleh AF, Gait MJ, Stuckey DJ, Clarke K, Davies KE, Wood MJ. Diaphragm rescue alone prevents heart dysfunction in dystrophic mice. Human Molecular Genetics. 20: 413-21. PMID 21062902 DOI: 10.1093/hmg/ddq477  0.316
2011 Fairclough R, Powell D, Squire S, Potter A, Bareja A, Russell A, Davies S, Davies K. P05 Utrophin upregulation in DMD therapy: current status and new tools for the future Neuromuscular Disorders. 21: S8. DOI: 10.1016/S0960-8966(11)70024-4  0.568
2010 Chodroff RA, Goodstadt L, Sirey TM, Oliver PL, Davies KE, Green ED, Molnár Z, Ponting CP. Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. Genome Biology. 11: R72. PMID 20624288 DOI: 10.1186/Gb-2010-11-7-R72  0.771
2010 Clarke WT, Edwards B, McCullagh KJ, Kemp MW, Moorwood C, Sherman DL, Burgess M, Davies KE. Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons. Journal of Cell Science. 123: 2543-52. PMID 20587592 DOI: 10.1242/jcs.059113  0.677
2010 Li D, Bareja A, Judge L, Yue Y, Lai Y, Fairclough R, Davies KE, Chamberlain JS, Duan D. Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. Journal of Cell Science. 123: 2008-13. PMID 20483958 DOI: 10.1242/Jcs.064808  0.638
2010 Turner BJ, Ackerley S, Davies KE, Talbot K. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice. Human Molecular Genetics. 19: 815-24. PMID 20008901 DOI: 10.1093/Hmg/Ddp550  0.714
2010 Goyenvalle A, Babbs A, Powell D, Kole R, Fletcher S, Wilton SD, Davies KE. Prevention of dystrophic pathology in severely affected dystrophin/utrophin-deficient mice by morpholino-oligomer-mediated exon-skipping. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 198-205. PMID 19844193 DOI: 10.1038/mt.2009.248  0.397
2010 Fairclough R, Davies K. P25 Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation Neuromuscular Disorders. 20: S12. DOI: 10.1016/S0960-8966(10)70040-7  0.576
2010 Bareja A, Fairclough R, Potter A, Powell D, Squire S, Davies K. P23 Assessing the effects of exercise-induced stress on the Fiona mouse model Neuromuscular Disorders. 20: S11. DOI: 10.1016/S0960-8966(10)70038-9  0.567
2009 Bäumer D, Lee S, Nicholson G, Davies JL, Parkinson NJ, Murray LM, Gillingwater TH, Ansorge O, Davies KE, Talbot K. Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy. Plos Genetics. 5: e1000773. PMID 20019802 DOI: 10.1371/Journal.Pgen.1000773  0.741
2009 Bitoun E, Finelli MJ, Oliver PL, Lee S, Davies KE. AF4 is a critical regulator of the IGF-1 signaling pathway during Purkinje cell development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15366-74. PMID 20007461 DOI: 10.1523/Jneurosci.5188-09.2009  0.786
2009 Oliver PL, Davies KE. Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk. Human Molecular Genetics. 18: 4576-89. PMID 19729413 DOI: 10.1093/Hmg/Ddp425  0.758
2009 Davies K, Wynshaw-Boris A. Human genetics: conceptual and practical advances in the post-genome era Current Opinion in Genetics and Development. 19: 193-195. PMID 19481439 DOI: 10.1016/J.Gde.2009.05.002  0.379
2009 Nowak KJ, Ravenscroft G, Jackaman C, Filipovska A, Davies SM, Lim EM, Squire SE, Potter AC, Baker E, Clément S, Sewry CA, Fabian V, Crawford K, Lessard JL, Griffiths LM, ... ... Davies KE, et al. Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin. The Journal of Cell Biology. 185: 903-15. PMID 19468071 DOI: 10.1083/jcb.200812132  0.311
2009 Goyenvalle A, Babbs A, van Ommen GJ, Garcia L, Davies KE. Enhanced exon-skipping induced by U7 snRNA carrying a splicing silencer sequence: Promising tool for DMD therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1234-40. PMID 19455105 DOI: 10.1038/mt.2009.113  0.379
2009 Becker EB, Oliver PL, Glitsch MD, Banks GT, Achilli F, Hardy A, Nolan PM, Fisher EM, Davies KE. A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 6706-11. PMID 19351902 DOI: 10.1073/Pnas.0810599106  0.807
2009 Bitoun E, Davies KE. The robotic mouse: understanding the role of AF4, a cofactor of transcriptional elongation and chromatin remodelling, in purkinje cell function. Cerebellum (London, England). 8: 175-83. PMID 19340490 DOI: 10.1007/S12311-009-0101-0  0.788
2009 Turner BJ, Parkinson NJ, Davies KE, Talbot K. Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model. Neurobiology of Disease. 34: 511-7. PMID 19332122 DOI: 10.1016/J.Nbd.2009.03.005  0.739
2009 Kemp MW, Edwards B, Burgess M, Clarke WT, Nicholson G, Parry DA, Davies KE. Syncoilin isoform organization and differential expression in murine striated muscle. Journal of Structural Biology. 165: 196-203. PMID 19070665 DOI: 10.1016/j.jsb.2008.11.002  0.647
2009 Hoerder-Suabedissen A, Wang WZ, Lee S, Davies KE, Goffinet AM, Raki? S, Parnavelas J, Reim K, Nicoli? M, Paulsen O, Molnár Z. Novel markers reveal subpopulations of subplate neurons in the murine cerebral cortex. Cerebral Cortex (New York, N.Y. : 1991). 19: 1738-50. PMID 19008461 DOI: 10.1093/Cercor/Bhn195  0.53
2009 Briese M, Esmaeili B, Fraboulet S, Burt EC, Christodoulou S, Towers PR, Davies KE, Sattelle DB. Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan. Human Molecular Genetics. 18: 97-104. PMID 18829666 DOI: 10.1093/hmg/ddn320  0.608
2008 Cauchi RJ, Davies KE, Liu JL. A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila. Plos Genetics. 4: e1000265. PMID 19023405 DOI: 10.1371/Journal.Pgen.1000265  0.721
2008 Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcón M, Oliver PL, Davies KE, Geschwind DH, Monaco AP, Fisher SE. A functional genetic link between distinct developmental language disorders. The New England Journal of Medicine. 359: 2337-45. PMID 18987363 DOI: 10.1056/Nejmoa0802828  0.767
2008 Johnson RD, Oliver PL, Davies KE. SNARE proteins and schizophrenia: linking synaptic and neurodevelopmental hypotheses. Acta Biochimica Polonica. 55: 619-28. PMID 18985177 DOI: 10.18388/Abp.2008_3022  0.726
2008 McCullagh KJ, Edwards B, Kemp MW, Giles LC, Burgess M, Davies KE. Analysis of skeletal muscle function in the C57BL6/SV129 syncoilin knockout mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 339-51. PMID 18594912 DOI: 10.1007/s00335-008-9120-2  0.514
2008 Doran G, Davies KE, Talbot K. Activation of mutant protein kinase Cgamma leads to aberrant sequestration and impairment of its cellular function. Biochemical and Biophysical Research Communications. 372: 447-53. PMID 18503760 DOI: 10.1016/J.Bbrc.2008.05.072  0.709
2008 Talbot K, Davies KE. Is good housekeeping the key to motor neuron survival? Cell. 133: 572-4. PMID 18485864 DOI: 10.1016/J.Cell.2008.05.002  0.711
2008 Gulston MK, Rubtsov DV, Atherton HJ, Clarke K, Davies KE, Lilley KS, Griffin JL. A combined metabolomic and proteomic investigation of the effects of a failure to express dystrophin in the mouse heart. Journal of Proteome Research. 7: 2069-77. PMID 18386883 DOI: 10.1021/pr800070p  0.304
2008 Baban D, Davies KE. Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for dystrophin deficiency. Neuromuscular Disorders : Nmd. 18: 239-47. PMID 18343112 DOI: 10.1016/j.nmd.2007.11.011  0.365
2008 't Hoen PA, de Meijer EJ, Boer JM, Vossen RH, Turk R, Maatman RG, Davies KE, van Ommen GJ, van Deutekom JC, den Dunnen JT. Generation and characterization of transgenic mice with the full-length human DMD gene. The Journal of Biological Chemistry. 283: 5899-907. PMID 18083704 DOI: 10.1074/jbc.M709410200  0.372
2008 Fairclough R, Potter A, Powell D, Squire S, Bland M, Bareja A, Tinsley J, Davies K. T.P.4.02 Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy Neuromuscular Disorders. 18: 812. DOI: 10.1016/J.Nmd.2008.06.302  0.575
2008 Willmann R, Rüegg M, Fairclough R, Davies K, Possekel S, Meier T. T.P.3.03 TREAT-NMD-Activity 7: Accelerate preclinical phase of new therapeutic treatment development Neuromuscular Disorders. 18: 794. DOI: 10.1016/J.Nmd.2008.06.242  0.566
2008 Nowak KJ, Ravenscroft G, Jackaman C, Lim EM, Sewry CA, Potter A, Squire S, Fisher R, Baker E, Feng JJ, Marston S, Fabian V, Morling PJ, Bakker AJ, Griffiths LM, ... ... Davies KE, et al. A mutant skeletal muscle alpha-actin gene, fused to enhanced green fluorescent protein (EGFP) produces a unique myopathic mouse model Neuromuscular Disorders. 18: 785-786. DOI: 10.1016/J.Nmd.2008.06.213  0.325
2007 Kemp MW, Davies KE. The role of intermediate filament proteins in the development of neurological disease. Critical Reviews in Neurobiology. 19: 1-27. PMID 19166389 DOI: 10.1615/Critrevneurobiol.V19.I1.10  0.365
2007 Talbot K, Davies KE. Chapter 7 Spinal muscular atrophies and hereditary motor neuropathies. Handbook of Clinical Neurology. 82: 141-53. PMID 18808892 DOI: 10.1016/S0072-9752(07)80010-8  0.714
2007 Molnár Z, Hoerder-Suabedissen A, Wang WZ, DeProto J, Davies K, Lee S, Jacobs EC, Campagnoni AT, Paulsen O, Piñon MC, Cheung AF. Genes involved in the formation of the earliest cortical circuits. Novartis Foundation Symposium. 288: 212-24; discussion 2. PMID 18494261 DOI: 10.1016/J.Ijdevneu.2012.10.031  0.463
2007 Vernes SC, Spiteri E, Nicod J, Groszer M, Taylor JM, Davies KE, Geschwind DH, Fisher SE. High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders. American Journal of Human Genetics. 81: 1232-50. PMID 17999362 DOI: 10.1086/522238  0.554
2007 Trülzsch B, Garnett C, Davies K, Wood M. Knockdown of SMN by RNA interference induces apoptosis in differentiated P19 neural stem cells. Brain Research. 1183: 1-9. PMID 17976539 DOI: 10.1016/j.brainres.2007.09.025  0.371
2007 Mattei E, Corbi N, Di Certo MG, Strimpakos G, Severini C, Onori A, Desantis A, Libri V, Buontempo S, Floridi A, Fanciulli M, Baban D, Davies KE, Passananti C. Utrophin up-regulation by an artificial transcription factor in transgenic mice. Plos One. 2: e774. PMID 17712422 DOI: 10.1371/journal.pone.0000774  0.385
2007 McCullagh KJ, Edwards B, Poon E, Lovering RM, Paulin D, Davies KE. Intermediate filament-like protein syncoilin in normal and myopathic striated muscle. Neuromuscular Disorders : Nmd. 17: 970-9. PMID 17629480 DOI: 10.1016/j.nmd.2007.06.004  0.508
2007 Oliver PL, Keays DA, Davies KE. Behavioural characterisation of the robotic mouse mutant. Behavioural Brain Research. 181: 239-47. PMID 17532061 DOI: 10.1016/J.Bbr.2007.04.012  0.741
2007 Oliver PL, Bitoun E, Davies KE. Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 412-24. PMID 17514509 DOI: 10.1007/S00335-007-9014-8  0.808
2007 Rezniczek GA, Konieczny P, Nikolic B, Reipert S, Schneller D, Abrahamsberg C, Davies KE, Winder SJ, Wiche G. Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan. The Journal of Cell Biology. 176: 965-77. PMID 17389230 DOI: 10.1083/jcb.200604179  0.305
2007 Li Y, Huang J, Zhao YL, He J, Wang W, Davies KE, Nosé V, Xiao S. UTRN on chromosome 6q24 is mutated in multiple tumors. Oncogene. 26: 6220-8. PMID 17384672 DOI: 10.1038/sj.onc.1210432  0.331
2007 Jeans AF, Oliver PL, Johnson R, Capogna M, Vikman J, Molnár Z, Babbs A, Partridge CJ, Salehi A, Bengtsson M, Eliasson L, Rorsman P, Davies KE. A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse. Proceedings of the National Academy of Sciences of the United States of America. 104: 2431-6. PMID 17283335 DOI: 10.1073/Pnas.0610222104  0.793
2007 Keays DA, Tian G, Poirier K, Huang GJ, Siebold C, Cleak J, Oliver PL, Fray M, Harvey RJ, Molnár Z, Piñon MC, Dear N, Valdar W, Brown SD, Davies KE, et al. Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell. 128: 45-57. PMID 17218254 DOI: 10.1016/J.Cell.2006.12.017  0.794
2007 Bitoun E, Oliver PL, Davies KE. The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. Human Molecular Genetics. 16: 92-106. PMID 17135274 DOI: 10.1093/Hmg/Ddl444  0.782
2006 Vernes SC, Nicod J, Elahi FM, Coventry JA, Kenny N, Coupe AM, Bird LE, Davies KE, Fisher SE. Functional genetic analysis of mutations implicated in a human speech and language disorder. Human Molecular Genetics. 15: 3154-67. PMID 16984964 DOI: 10.1093/Hmg/Ddl392  0.551
2006 Davies KE, Nowak KJ. Molecular mechanisms of muscular dystrophies: old and new players. Nature Reviews. Molecular Cell Biology. 7: 762-73. PMID 16971897 DOI: 10.1038/nrm2024  0.36
2006 Towers PR, Lescure P, Baban D, Malek JA, Duarte J, Jones E, Davies KE, Ségalat L, Sattelle DB. Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18). Genomics. 88: 642-9. PMID 16962739 DOI: 10.1016/j.ygeno.2006.07.014  0.585
2006 Jiang Y, Oliver P, Davies KE, Platt N. Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells. The Journal of Biological Chemistry. 281: 11834-45. PMID 16407294 DOI: 10.1074/Jbc.M507599200  0.721
2006 Ackerley S, James PA, Kalli A, French S, Davies KE, Talbot K. A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes. Human Molecular Genetics. 15: 347-54. PMID 16368711 DOI: 10.1093/Hmg/Ddi452  0.716
2005 Bitoun E, Davies KE. The robotic mouse: unravelling the function of AF4 in the cerebellum. Cerebellum (London, England). 4: 250-60. PMID 16321881 DOI: 10.1080/14734220500325897  0.781
2005 Brown SC, Torelli S, Ugo I, De Biasia F, Howman EV, Poon E, Britton J, Davies KE, Muntoni F. Syncoilin upregulation in muscle of patients with neuromuscular disease. Muscle & Nerve. 32: 715-25. PMID 16124004 DOI: 10.1002/mus.20431  0.32
2005 Oliver PL, Davies KE. Analysis of human neurological disorders using mutagenesis in the mouse. Clinical Science (London, England : 1979). 108: 385-97. PMID 15831088 DOI: 10.1042/Cs20050041  0.783
2005 Nowak K, McCullagh K, Poon E, Davies KE. Muscular dystrophies related to the cytoskeleton/nuclear envelope. Novartis Foundation Symposium. 264: 98-111; discussion 1. PMID 15773750 DOI: 10.1002/0470093765.Ch8  0.373
2005 Jones GL, Sang E, Goddard C, Mortishire-Smith RJ, Sweatman BC, Haselden JN, Davies K, Grace AA, Clarke K, Griffin JL. A functional analysis of mouse models of cardiac disease through metabolic profiling. The Journal of Biological Chemistry. 280: 7530-9. PMID 15546876 DOI: 10.1074/jbc.M410200200  0.332
2004 Rastan S, Hough T, Kierman A, Hardisty R, Erven A, Gray IC, Voeling S, Isaacs A, Tsai H, Strivens M, Washbourne R, Thornton C, Greenaway S, Hewitt M, McCormick S, ... ... Davies K, et al. Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders. Genetica. 122: 47-9. PMID 15619960 DOI: 10.1007/S10709-004-1930-X  0.359
2004 Moore CJ, Daly EM, Tassone F, Tysoe C, Schmitz N, Ng V, Chitnis X, McGuire P, Suckling J, Davies KE, Hagerman RJ, Hagerman PJ, Murphy KC, Murphy DG. The effect of pre-mutation of X chromosome CGG trinucleotide repeats on brain anatomy. Brain : a Journal of Neurology. 127: 2672-81. PMID 15483045 DOI: 10.1093/Brain/Awh256  0.344
2004 Anderson KN, Baban D, Oliver PL, Potter A, Davies KE. Expression profiling in spinal muscular atrophy reveals an RNA binding protein deficit. Neuromuscular Disorders : Nmd. 14: 711-22. PMID 15482955 DOI: 10.1016/J.Nmd.2004.08.009  0.765
2004 Nowak KJ, Davies KE. Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment. Embo Reports. 5: 872-6. PMID 15470384 DOI: 10.1038/sj.embor.7400221  0.391
2004 Oliver PL, Bitoun E, Clark J, Jones EL, Davies KE. Mediation of Af4 protein function in the cerebellum by Siah proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 14901-6. PMID 15459319 DOI: 10.1073/Pnas.0406196101  0.789
2004 Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, et al. The European dimension for the mouse genome mutagenesis program. Nature Genetics. 36: 925-7. PMID 15340424 DOI: 10.1038/Ng0904-925  0.326
2004 Ilkovski B, Nowak KJ, Domazetovska A, Maxwell AL, Clement S, Davies KE, Laing NG, North KN, Cooper ST. Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. Human Molecular Genetics. 13: 1727-43. PMID 15198992 DOI: 10.1093/Hmg/Ddh185  0.324
2004 Anderson KN, Potter AC, Piccenna LG, Quah AK, Davies KE, Cheema SS. Isolation and culture of motor neurons from the newborn mouse spinal cord. Brain Research. Brain Research Protocols. 12: 132-6. PMID 15013463 DOI: 10.1016/j.brainresprot.2003.10.001  0.326
2004 Trülzsch B, Davies K, Wood M. Survival of motor neuron gene downregulation by RNAi: towards a cell culture model of spinal muscular atrophy. Brain Research. Molecular Brain Research. 120: 145-50. PMID 14741404 DOI: 10.1016/J.MOLBRAINRES.2003.10.015  0.394
2004 Weir AP, Morgan JE, Davies KE. A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration. Neuromuscular Disorders : Nmd. 14: 19-23. PMID 14659408 DOI: 10.1016/j.nmd.2003.09.004  0.306
2003 Moghadaszadeh B, Albrechtsen R, Guo LT, Zaik M, Kawaguchi N, Borup RH, Kronqvist P, Schroder HD, Davies KE, Voit T, Nielsen FC, Engvall E, Wewer UM. Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins. Human Molecular Genetics. 12: 2467-79. PMID 12915458 DOI: 10.1093/hmg/ddg264  0.365
2003 Anderson K, Potter A, Baban D, Davies KE. Protein expression changes in spinal muscular atrophy revealed with a novel antibody array technology. Brain : a Journal of Neurology. 126: 2052-64. PMID 12847076 DOI: 10.1093/brain/awg208  0.406
2003 Talbot K, Davies K. Musculoskeletal diseases: from complex genetics to therapy. Current Opinion in Pharmacology. 3: 277-9. PMID 12810192 DOI: 10.1016/S1471-4892(03)00044-4  0.667
2003 Chan YB, Miguel-Aliaga I, Franks C, Thomas N, Trülzsch B, Sattelle DB, Davies KE, van den Heuvel M. Neuromuscular defects in a Drosophila survival motor neuron gene mutant. Human Molecular Genetics. 12: 1367-76. PMID 12783845 DOI: 10.1093/Hmg/Ddg157  0.612
2003 Khurana TS, Davies KE. Pharmacological strategies for muscular dystrophy. Nature Reviews. Drug Discovery. 2: 379-90. PMID 12750741 DOI: 10.1038/nrd1085  0.352
2003 Cerletti M, Negri T, Cozzi F, Colpo R, Andreetta F, Croci D, Davies KE, Cornelio F, Pozza O, Karpati G, Gilbert R, Mora M. Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer. Gene Therapy. 10: 750-7. PMID 12704413 DOI: 10.1038/sj.gt.3301941  0.361
2003 Isaacs AM, Oliver PL, Jones EL, Jeans A, Potter A, Hovik BH, Nolan PM, Vizor L, Glenister P, Simon AK, Gray IC, Spurr NK, Brown SD, Hunter AJ, Davies KE. A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1631-7. PMID 12629167 DOI: 10.1523/Jneurosci.23-05-01631.2003  0.771
2003 Jimenez-Mallebrera C, Davies K, Putt W, Edwards YH. A study of short utrophin isoforms in mice deficient for full-length utrophin. Mammalian Genome. 14: 47-60. PMID 12532267 DOI: 10.1007/S00335-002-3044-Z  0.349
2003 Anderson K, Pouting C, Potter A, Davies K. Motor Neurons and Microarrays-Understanding the Pathogenesis of Spinal Muscular Atrophy Clinical Science. 104: 40P-41P. DOI: 10.1042/CS104040PB  0.318
2003 Trülzsch B, Davies K, Wood M. Characterisation of catalytic nucleic acids targeting the survival of motor neuron messenger RNA Neuroscience Research Communications. 32: 95-106. DOI: 10.1002/NRC.10064  0.381
2002 Squire S, Raymackers JM, Vandebrouck C, Potter A, Tinsley J, Fisher R, Gillis JM, Davies KE. Prevention of pathology in mdx mice by expression of utrophin: analysis using an inducible transgenic expression system. Human Molecular Genetics. 11: 3333-44. PMID 12471059 DOI: 10.1093/Hmg/11.26.3333  0.335
2002 Griffin JL, Sang E, Evens T, Davies K, Clarke K. Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy. Febs Letters. 530: 109-116. PMID 12387876 DOI: 10.1016/S0014-5793(02)03437-3  0.315
2002 Isaacs AM, Jeans A, Oliver PL, Vizor L, Brown SD, Hunter AJ, Davies KE. Identification of a new Pmp22 mouse mutant and trafficking analysis of a Pmp22 allelic series suggesting that protein aggregates may be protective in Pmp22-associated peripheral neuropathy. Molecular and Cellular Neurosciences. 21: 114-25. PMID 12359155 DOI: 10.1042/Cs104041P  0.763
2002 Weir AP, Burton EA, Harrod G, Davies KE. A- and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle. The Journal of Biological Chemistry. 277: 45285-90. PMID 12235137 DOI: 10.1074/jbc.M205177200  0.319
2002 Perkins KJ, Davies KE. The role of utrophin in the potential therapy of Duchenne muscular dystrophy. Neuromuscular Disorders : Nmd. 12: S78-89. PMID 12206801 DOI: 10.1016/S0960-8966(02)00087-1  0.396
2002 Vargas JD, Culetto E, Ponting CP, Miguel-Aliaga I, Davies KE, Sattelle DB. Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene. Mechanisms of Development. 117: 289-92. PMID 12204272 DOI: 10.1016/S0925-4773(02)00182-X  0.561
2002 Blake DJ, Weir A, Newey SE, Davies KE. Function and genetics of dystrophin and dystrophin-related proteins in muscle. Physiological Reviews. 82: 291-329. PMID 11917091 DOI: 10.1152/physrev.00028.2001  0.351
2002 Poon E, Howman EV, Newey SE, Davies KE. Association of syncoilin and desmin: linking intermediate filament proteins to the dystrophin-associated protein complex. The Journal of Biological Chemistry. 277: 3433-9. PMID 11694502 DOI: 10.1074/jbc.M105273200  0.316
2001 Culle MJ, Walsh JM, Tinsle JM, Fisher R, Davies KE. Immunogold confirmation that utrophin is localized to the normal position of dystrophin in dystrophin-negative transgenic mouse muscle. The Histochemical Journal. 33: 579-83. PMID 12005030 DOI: 10.1023/A:1014964127156  0.323
2001 Perkins KJ, Burton EA, Davies KE. The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy. Nucleic Acids Research. 29: 4843-50. PMID 11726694 DOI: 10.1093/Nar/29.23.4843  0.343
2001 Fisher R, Tinsley JM, Phelps SR, Squire SE, Townsend ER, Martin JE, Davies KE. Non-toxic ubiquitous over-expression of utrophin in the mdx mouse. Neuromuscular Disorders : Nmd. 11: 713-21. PMID 11595513 DOI: 10.1016/S0960-8966(01)00220-6  0.371
2001 Talbot K, Davies KE. Spinal muscular atrophy. Seminars in Neurology. 21: 189-97. PMID 11442327 DOI: 10.1055/S-2001-15264  0.736
2001 Skordis LA, Dunckley MG, Burglen L, Campbell L, Talbot K, Patel S, Melki J, Davies KE, Dubowitz V, Muntoni F. Characterisation of novel point mutations in the survival motor neuron gene SMN, in three patients with SMA. Human Genetics. 108: 356-7. PMID 11379882 DOI: 10.1007/S004390100497  0.723
2001 Nakamura A, Harrod GV, Davies KE. Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice. Neuromuscular Disorders : Nmd. 11: 251-9. PMID 11297940 DOI: 10.1016/S0960-8966(00)00201-7  0.317
2000 Hopkins JC, Bia BL, Crilley JG, Boehm EA, Sang AE, Tinsley JM, King LM, Radda GK, Davies KE, Clarke K. Muscular dystrophy: from gene to patient. Magma (New York, N.Y.). 11: 7-9. PMID 11186993 DOI: 10.1007/Bf02678481  0.32
2000 Miguel-Aliaga I, Chan YB, Davies KE, van den Heuvel M. Disruption of SMN function by ectopic expression of the human SMN gene in Drosophila. Febs Letters. 486: 99-102. PMID 11113446 DOI: 10.1016/S0014-5793(00)02243-2  0.419
2000 Newey SE, Benson MA, Ponting CP, Davies KE, Blake DJ. Alternative splicing of dystrobrevin regulates the stoichiometry of syntrophin binding to the dystrophin protein complex. Current Biology : Cb. 10: 1295-8. PMID 11069112 DOI: 10.1016/S0960-9822(00)00760-0  0.316
2000 Rafael JA, Nitta Y, Peters J, Davies KE. Testing of SHIRPA, a mouse phenotypic assessment protocol, on Dmd(mdx) and Dmd(mdx3cv) dystrophin-deficient mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 725-8. PMID 10967129 DOI: 10.1007/s003350010149  0.32
2000 Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, ... ... Davies K, et al. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nature Genetics. 25: 440-3. PMID 10932191 DOI: 10.1038/78140  0.381
2000 Isaacs AM, Davies KE, Hunter AJ, Nolan PM, Vizor L, Peters J, Gale DG, Kelsell DP, Latham ID, Chase JM, Fisher EM, Bouzyk MM, Potter A, Masih M, Walsh FS, et al. Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy. Human Molecular Genetics. 9: 1865-71. PMID 10915775 DOI: 10.1046/J.1529-8027.2001.01008-19.X  0.396
2000 Corbi N, Libri V, Fanciulli M, Tinsley JM, Davies KE, Passananti C. The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription. Gene Therapy. 7: 1076-83. PMID 10871758 DOI: 10.1038/sj.gt.3301204  0.32
2000 Rafael JA, Townsend ER, Squire SE, Potter AC, Chamberlain JS, Davies KE. Dystrophin and utrophin influence fiber type composition and post-synaptic membrane structure. Human Molecular Genetics. 9: 1357-67. PMID 10814717 DOI: 10.1093/HMG/9.9.1357  0.348
2000 Rodrigues NR, Theodosiou AM, Nesbit MA, Campbell L, Tandle AT, Saranath D, Davies KE. Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus. Genomics. 65: 53-61. PMID 10777665 DOI: 10.1006/geno.2000.6138  0.356
2000 Campbell L, Hunter KM, Mohaghegh P, Tinsley JM, Brasch MA, Davies KE. Direct interaction of Smn with dp103, a putative RNA helicase: a role for Smn in transcription regulation? Human Molecular Genetics. 9: 1093-100. PMID 10767334 DOI: 10.1093/Hmg/9.7.1093  0.43
2000 Owen N, Doe CL, Mellor J, Davies KE. Characterization of the Schizosaccharomyces pombe orthologue of the human survival motor neuron (SMN) protein. Human Molecular Genetics. 9: 675-84. PMID 10749974 DOI: 10.1093/Hmg/9.5.675  0.434
2000 Wakefield PM, Tinsley JM, Wood MJ, Gilbert R, Karpati G, Davies KE. Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene. Gene Therapy. 7: 201-4. PMID 10694796 DOI: 10.1038/sj.gt.3301066  0.34
2000 Miller WJ, Skinner JA, Foss GS, Davies KE. Localization of the fragile X mental retardation 2 (FMR2) protein in mammalian brain. The European Journal of Neuroscience. 12: 381-4. PMID 10651894 DOI: 10.1046/j.1460-9568.2000.00921.x  0.342
1999 Burton EA, Tinsley JM, Holzfeind PJ, Rodrigues NR, Davies KE. A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 96: 14025-30. PMID 10570192 DOI: 10.1073/Pnas.96.24.14025  0.351
1999 Miguel-Aliaga I, Culetto E, Walker DS, Baylis HA, Sattelle DB, Davies KE. The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability. Human Molecular Genetics. 8: 2133-43. PMID 10545592 DOI: 10.1093/Hmg/8.12.2133  0.619
1999 Bia BL, Cassidy PJ, Young ME, Rafael JA, Leighton B, Davies KE, Radda GK, Clarke K. Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy. Journal of Molecular and Cellular Cardiology. 31: 1857-62. PMID 10525423 DOI: 10.1006/Jmcc.1999.1018  0.319
1999 Mohaghegh P, Rodrigues NR, Owen N, Ponting CP, Le TT, Burghes AH, Davies KE. Analysis of mutations in the tudor domain of the survival motor neuron protein SMN. European Journal of Human Genetics : Ejhg. 7: 519-25. PMID 10439956 DOI: 10.1038/Sj.Ejhg.5200346  0.407
1999 Gilbert R, Nalbantoglu J, Petrof BJ, Ebihara S, Guibinga GH, Tinsley JM, Kamen A, Massie B, Davies KE, Karpati G. Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles. Human Gene Therapy. 10: 1299-310. PMID 10365661 DOI: 10.1089/10430349950017987  0.355
1999 Rafael JA, Trickett JI, Potter AC, Davies KE. Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice. Muscle & Nerve. 22: 517-9. PMID 10204788 DOI: 10.1002/(SICI)1097-4598(199904)22:4<517::AID-MUS14>3.0.CO;2-6  0.305
1999 Gramolini AO, Angus LM, Schaeffer L, Burton EA, Tinsley JM, Davies KE, Changeux JP, Jasmin BJ. Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 3223-7. PMID 10077665 DOI: 10.1073/Pnas.96.6.3223  0.355
1999 Holzfeind PJ, Ambrose HJ, Newey SE, Nawrotzki RA, Blake DJ, Davies KE. Tissue-selective expression of alpha-dystrobrevin is determined by multiple promoters. The Journal of Biological Chemistry. 274: 6250-8. PMID 10037712 DOI: 10.1074/jbc.274.10.6250  0.317
1998 Tinsley J, Deconinck N, Fisher R, Kahn D, Phelps S, Gillis JM, Davies K. Expression of full-length utrophin prevents muscular dystrophy in mdx mice. Nature Medicine. 4: 1441-4. PMID 9846586 DOI: 10.1038/4033  0.32
1998 Trump D, Dixon PH, Mumm S, Wooding C, Davies KE, Schlessinger D, Whyte MP, Thakker RV. Localisation of X linked recessive idiopathic hypoparathyroidism to a 1.5 Mb region on Xq26-q27. Journal of Medical Genetics. 35: 905-9. PMID 9832036 DOI: 10.1136/Jmg.35.11.905  0.302
1998 Talbot K, Miguel-Aliaga I, Mohaghegh P, Ponting CP, Davies KE. Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Human Molecular Genetics. 7: 2149-56. PMID 9817934 DOI: 10.1093/Hmg/7.13.2149  0.739
1998 Taylor JE, Thomas NH, Lewis CM, Abbs SJ, Rodrigues NR, Davies KE, Mathew CG. Correlation of SMNt and SMNc gene copy number with age of onset and survival in spinal muscular atrophy. European Journal of Human Genetics : Ejhg. 6: 467-74. PMID 9801871 DOI: 10.1038/sj.ejhg.5200210  0.38
1998 Campbell L, Daniels RJ, Dubowitz V, Davies KE. Maternal mosaicism for a second mutational event in a type I spinal muscular atrophy family. American Journal of Human Genetics. 63: 37-44. PMID 9634516 DOI: 10.1086/301918  0.388
1998 Paulsen M, Davies KR, Bowden LM, Villar AJ, Franck O, Fuermann M, Dean WL, Moore TF, Rodrigues N, Davies KE, Hu RJ, Feinberg AP, Maher ER, Reik W, Walter J. Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5. Human Molecular Genetics. 7: 1149-59. PMID 9618174 DOI: 10.1093/hmg/7.7.1149  0.344
1998 Vater R, Young C, Anderson LV, Lindsay S, Blake DJ, Davies KE, Zuellig R, Slater CR. Utrophin mRNA expression in muscle is not restricted to the neuromuscular junction. Molecular and Cellular Neurosciences. 10: 229-42. PMID 9604203 DOI: 10.1006/Mcne.1998.0661  0.304
1998 Rafael JA, Tinsley JM, Potter AC, Deconinck AE, Davies KE. Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice. Nature Genetics. 19: 79-82. PMID 9590295 DOI: 10.1038/ng0598-79  0.339
1998 Chakrabarti L, Bristulf J, Foss GS, Davies KE. Expression of the murine homologue of FMR2 in mouse brain and during development. Human Molecular Genetics. 7: 441-8. PMID 9467002 DOI: 10.1093/hmg/7.3.441  0.345
1998 Gilbert R, Nalbanoglu J, Tinsley JM, Massie B, Davies KE, Karpati G. Efficient utrophin expression following adenovirus gene transfer in dystrophic muscle. Biochemical and Biophysical Research Communications. 242: 244-7. PMID 9439643 DOI: 10.1006/Bbrc.1997.7936  0.328
1998 Gramolini AO, Burton EA, Tinsley JM, Ferns MJ, Cartaud A, Cartaud J, Davies KE, Lunde JA, Jasmin BJ. Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism. The Journal of Biological Chemistry. 273: 736-43. PMID 9422725 DOI: 10.1074/Jbc.273.2.736  0.368
1997 Davies KE. Challenges in Duchenne muscular dystrophy. Neuromuscular Disorders : Nmd. 7: 482-6. PMID 9447604 DOI: 10.1016/S0960-8966(97)00107-7  0.334
1997 Ritchie RJ, Chakrabarti L, Knight SJ, Harding RM, Davies KE. Population genetics of the FRAXE and FRAXF GCC repeats, and a novel CGG repeat, in Xq28. American Journal of Medical Genetics. 73: 463-9. PMID 9415475 DOI: 10.1002/(SICI)1096-8628(19971231)73:4<463::AID-AJMG16>3.0.CO;2-P  0.318
1997 Deconinck N, Tinsley J, De Backer F, Fisher R, Kahn D, Phelps S, Davies K, Gillis JM. Expression of truncated utrophin leads to major functional improvements in dystrophin-deficient muscles of mice. Nature Medicine. 3: 1216-21. PMID 9359695 DOI: 10.1038/NM1197-1216  0.323
1997 Deconinck AE, Rafael JA, Skinner JA, Brown SC, Potter AC, Metzinger L, Watt DJ, Dickson JG, Tinsley JM, Davies KE. Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy. Cell. 90: 717-27. PMID 9288751 DOI: 10.1016/S0092-8674(00)80532-2  0.352
1997 Campbell L, Potter A, Ignatius J, Dubowitz V, Davies K. Genomic variation and gene conversion in spinal muscular atrophy: implications for disease process and clinical phenotype. American Journal of Human Genetics. 61: 40-50. PMID 9245983 DOI: 10.1086/513886  0.411
1997 Metzinger L, Blake DJ, Squier MV, Anderson LV, Deconinck AE, Nawrotzki R, Hilton-Jones D, Davies KE. Dystrobrevin deficiency at the sarcolemma of patients with muscular dystrophy. Human Molecular Genetics. 6: 1185-91. PMID 9215691 DOI: 10.1093/Hmg/6.7.1185  0.365
1997 Nesbit MA, Hodges MD, Campbell L, de Meulemeester TM, Alders M, Rodrigues NR, Talbot K, Theodosiou AM, Mannens MA, Nakamura Y, Little PF, Davies KE. Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2. Genomics. 42: 284-94. PMID 9192849 DOI: 10.1006/Geno.1997.4737  0.697
1997 Talbot K, Rodrigues NR, Ignatius J, Muntoni F, Davies KE. Gene conversion at the SMN locus in autosomal recessive spinal muscular atrophy does not predict a mild phenotype. Neuromuscular Disorders : Nmd. 7: 198-201. PMID 9185185 DOI: 10.1016/S0960-8966(97)00450-1  0.738
1997 Talbot K, Ponting CP, Theodosiou AM, Rodrigues NR, Surtees R, Mountford R, Davies KE. Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism? Human Molecular Genetics. 6: 497-500. PMID 9147655 DOI: 10.1093/Hmg/6.3.497  0.729
1997 Ambrose HJ, Blake DJ, Nawrotzki RA, Davies KE. Genomic organization of the mouse dystrobrevin gene: comparative analysis with the dystrophin gene. Genomics. 39: 359-69. PMID 9119373 DOI: 10.1006/geno.1996.4515  0.378
1997 Gramolini AO, Dennis CL, Tinsley JM, Robertson GS, Cartaud J, Davies KE, Jasmin BJ. Local transcriptional control of utrophin expression at the neuromuscular synapse. The Journal of Biological Chemistry. 272: 8117-20. PMID 9079621 DOI: 10.1074/Jbc.272.13.8117  0.352
1997 Deconinck AE, Potter AC, Tinsley JM, Wood SJ, Vater R, Young C, Metzinger L, Vincent A, Slater CR, Davies KE. Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice. The Journal of Cell Biology. 136: 883-94. PMID 9049253 DOI: 10.1083/Jcb.136.4.883  0.333
1997 Barnicoat AJ, Wang Q, Turk J, Green E, Mathew CG, Flynn G, Buckle V, Hirst M, Davies K, Bobrow M. Clinical, cytogenetic, and molecular analysis of three families with FRAXE. Journal of Medical Genetics. 34: 13-17. PMID 9032643 DOI: 10.1136/Jmg.34.1.13  0.318
1996 Talbot K, Rodrigues N, Bernert G, Bittner R, Davies K. Evidence for compound heterozygosity causing mild and severe forms of autosomal recessive spinal muscular atrophy. Journal of Medical Genetics. 33: 1019-21. PMID 9004135 DOI: 10.1136/Jmg.33.12.1019  0.734
1996 Tinsley JM, Potter AC, Phelps SR, Fisher R, Trickett JI, Davies KE. Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene. Nature. 384: 349-53. PMID 8934518 DOI: 10.1038/384349a0  0.36
1996 Rodrigues NR, Owen N, Talbot K, Patel S, Muntoni F, Ignatius J, Dubowitz V, Davies KE. Gene deletions in spinal muscular atrophy. Journal of Medical Genetics. 33: 93-6. PMID 8929942 DOI: 10.1136/Jmg.33.2.93  0.722
1996 Blake DJ, Tinsley JM, Davies KE. Utrophin: a structural and functional comparison to dystrophin. Brain Pathology (Zurich, Switzerland). 6: 37-47. PMID 8866746 DOI: 10.1111/J.1750-3639.1996.Tb00781.X  0.357
1996 Ponting CP, Blake DJ, Davies KE, Kendrick-Jones J, Winder SJ. ZZ and TAZ: new putative zinc fingers in dystrophin and other proteins. Trends in Biochemical Sciences. 21: 11-13. PMID 8848831 DOI: 10.1016/S0968-0004(06)80020-4  0.327
1996 Rodrigues NR, Talbot K, Davies KE. Molecular genetics of autosomal recessive spinal muscular atrophy. Molecular Medicine (Cambridge, Mass.). 2: 400-4. PMID 8827710 DOI: 10.1007/Bf03401899  0.682
1996 Chakrabarti L, Knight SJ, Flannery AV, Davies KE. A candidate gene for mild mental handicap at the FRAXE fragile site. Human Molecular Genetics. 5: 275-82. PMID 8824884 DOI: 10.1093/hmg/5.2.275  0.325
1996 Coleman MP, Ambrose HJ, Carrel L, Németh AH, Willard HF, Davies KE. A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status. Genomics. 31: 135-8. PMID 8808293 DOI: 10.1006/Geno.1996.0022  0.323
1996 Rowe PS, Goulding JN, Francis F, Oudet C, Econs MJ, Hanauer A, Lehrach H, Read AP, Mountford RC, Summerfield T, Weissenbach J, Fraser W, Drezner MK, Davies KE, O'Riordan JL. The gene for X-linked hypophosphataemic rickets maps to a 200-300kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE). Human Genetics. 97: 345-52. PMID 8786079 DOI: 10.1007/Bf02185769  0.318
1996 Nawrotzki R, Blake DJ, Davies KE. The genetic basis of neuromuscular disorders. Trends in Genetics : Tig. 12: 294-8. PMID 8783938 DOI: 10.1016/0168-9525(96)10033-0  0.372
1996 Theodosiou AM, Rodrigues NR, Nesbit MA, Ambrose HJ, Paterson H, McLellan-Arnold E, Boyd Y, Leversha MA, Owen N, Blake DJ, Ashworth A, Davies KE. A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region. Human Molecular Genetics. 5: 675-84. PMID 8733137 DOI: 10.1093/Hmg/5.5.675  0.359
1996 Dennis CL, Tinsley JM, Deconinck AE, Davies KE. Molecular and functional analysis of the utrophin promoter. Nucleic Acids Research. 24: 1646-52. PMID 8649981 DOI: 10.1093/nar/24.9.1646  0.351
1996 Blake DJ, Nawrotzki R, Peters MF, Froehner SC, Davies KE. Isoform diversity of dystrobrevin, the murine 87-kDa postsynaptic protein. The Journal of Biological Chemistry. 271: 7802-10. PMID 8631824 DOI: 10.1074/jbc.271.13.7802  0.344
1995 Schofield JN, Górecki DC, Blake DJ, Davies KE, Edwards YH. Dystroglycan mRNA expression during normal and mdx mouse embryogenesis: A comparison with utrophin and the apo-dystrophins Developmental Dynamics. 204: 178-185. PMID 8589441 DOI: 10.1002/Aja.1002040208  0.329
1995 Nguyen TM, Helliwell TR, Simmons C, Winder SJ, Kendrick-Jones J, Davies KE, Morris GE. Full-length and short forms of utrophin, the dystrophin-related protein. Febs Letters. 358: 262-6. PMID 7843413 DOI: 10.1016/0014-5793(94)01441-3  0.308
1995 Blake DJ, Tinsley JM, Davies KE, Knight AE, Winder SJ, Kendrick-Jones J. Coiled-coil regions in the carboxy-terminal domains of dystrophin and related proteins: potentials for protein-protein interactions. Trends in Biochemical Sciences. 20: 133-5. PMID 7770909 DOI: 10.1016/S0968-0004(00)88986-0  0.387
1995 Daniels RJ, Campbell L, Rodrigues NR, Francis MJ, Morrison KE, McLean M, MacKenzie A, Ignatius J, Dubowitz V, Davies KE. Genomic rearrangements in childhood spinal muscular atrophy: linkage disequilibrium with a null allele. Journal of Medical Genetics. 32: 93-6. PMID 7760328 DOI: 10.1136/Jmg.32.2.93  0.32
1995 Black GC, Coleman MP, Chen ZY, Nemeth AH, Davies KE, Craig IW. A bidirectional YAC walk from the Norrie disease (NDP) locus. Genomics. 25: 644-9. PMID 7759098 DOI: 10.1016/0888-7543(95)80006-8  0.332
1995 Rocques PJ, Clark J, Ball S, Crew J, Gill S, Christodoulou Z, Borts RH, Louis EJ, Davies KE, Cooper CS. The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes. Human Molecular Genetics. 4: 243-9. PMID 7757074 DOI: 10.1093/HMG/4.2.243  0.722
1995 Blake DJ, Schofield JN, Zuellig RA, Górecki DC, Phelps SR, Barnard EA, Edwards YH, Davies KE. G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain. Proceedings of the National Academy of Sciences of the United States of America. 92: 3697-701. PMID 7731967 DOI: 10.1073/Pnas.92.9.3697  0.324
1995 Dubowitz V, Daniels RJ, Davies KE. Olivopontocerebellar hypoplasia with anterior horn cell involvement (SMA) does not localize to chromosome 5q. Neuromuscular Disorders : Nmd. 5: 25-9. PMID 7719137 DOI: 10.1016/0960-8966(94)00043-9  0.324
1995 Rodrigues NR, Owen N, Talbot K, Ignatius J, Dubowitz V, Davies KE. Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy. Human Molecular Genetics. 4: 631-4. PMID 7633412 DOI: 10.1093/Hmg/4.4.631  0.74
1995 Jasmin BJ, Alameddine H, Lunde JA, Stetzkowski-Marden F, Collin H, Tinsley JM, Davies KE, Tomé FM, Parry DJ, Cartaud J. Expression of utrophin and its mRNA in denervated mdx mouse muscle. Febs Letters. 374: 393-8. PMID 7589578 DOI: 10.1016/0014-5793(95)01131-W  0.303
1995 Francis MJ, Nesbit MA, Theodosiou AM, Rodrigues NR, Campbell L, Christodoulou Z, Qureshi SJ, Porteous DJ, Brookes AJ, Davies KE. Mapping of retrotransposon sequences in the unstable region surrounding the spinal muscular atrophy locus in 5q13. Genomics. 27: 366-9. PMID 7558009 DOI: 10.1006/geno.1995.1059  0.36
1995 Francis F, Hennig S, Korn B, Reinhardt R, de Jong P, Poustka A, Lehrach H, Rowe PSN, Goulding JN, Summerfield T, Mountford R, Read AP, Popowska E, Pronicka E, Davies KE, et al. A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets Nature Genetics. 11: 130-136. PMID 7550339 DOI: 10.1038/Ng1095-130  0.368
1994 Blake DJ, Tinsley JM, Davies KE. The emerging family of dystrophin-related proteins. Trends in Cell Biology. 4: 19-23. PMID 14731825 DOI: 10.1016/0962-8924(94)90034-5  0.348
1994 Rowe PS, Goulding J, Read A, Lehrach H, Francis F, Hanauer A, Oudet C, Biancalana V, Kooh SW, Davies KE. Refining the genetic map for the region flanking the X-linked hypophosphataemic rickets locus (Xp22.1-22.2). Human Genetics. 93: 291-4. PMID 8125480 DOI: 10.1007/Bf00212025  0.313
1994 Coleman MP, Németh AH, Campbell L, Raut CP, Weissenbach J, Davies KE. A 1.8-Mb YAC contig in Xp11.23: identification of CpG islands and physical mapping of CA repeats in a region of high gene density. Genomics. 21: 337-43. PMID 8088827 DOI: 10.1006/geno.1994.1274  0.318
1994 Mérette C, Brzustowicz LM, Daniels RJ, Davies KE, Gilliam TC, Melki J, Munnich A, Pericak-Vance MA, Siddique T, Voosen B. An investigation of genetic heterogeneity and linkage disequilibrium in 161 families with spinal muscular atrophy. Genomics. 21: 27-33. PMID 8088801 DOI: 10.1006/Geno.1994.1220  0.305
1994 Tinsley JM, Blake DJ, Zuellig RA, Davies KE. Increasing complexity of the dystrophin-associated protein complex. Proceedings of the National Academy of Sciences of the United States of America. 91: 8307-13. PMID 8078878 DOI: 10.1073/Pnas.91.18.8307  0.352
1994 Schofield JN, Blake DJ, Simmons C, Morris GE, Tinsley JM, Davies KE, Edwards YH. Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines. Human Molecular Genetics. 3: 1309-16. PMID 7987307 DOI: 10.1093/Hmg/3.8.1309  0.318
1994 Komatsu H, Takeuchi Y, Miyanomae Y, Yoshioka H, Daniels R, Davies KE, Sawada T. Spinal muscular atrophy in trizygotic triplets. Acta Paediatrica Japonica; Overseas Edition. 36: 522-6. PMID 7825456 DOI: 10.1111/J.1442-200X.1994.Tb03239.X  0.34
1993 Tinsley JM, Blake DJ, Davies KE. Apo-dystrophin-3: a 2.2kb transcript from the DMD locus encoding the dystrophin glycoprotein binding site. Human Molecular Genetics. 2: 521-4. PMID 8518789 DOI: 10.1093/hmg/2.5.521  0.319
1993 Passos-Bueno MR, Byth BC, Rosenberg S, Takata RI, Bakker E, Beggs AH, Pavanello RC, Vainzof M, Davies KE, Zatz M. Severe nonspecific X-linked mental retardation caused by a proximally Xp located gene: intragenic heterogeneity or a new form of X-linked mental retardation? American Journal of Medical Genetics. 46: 172-5. PMID 8484404 DOI: 10.1002/Ajmg.1320460214  0.338
1993 Karpati G, Carpenter S, Morris GE, Davies KE, Guerin C, Holland P. Localization and quantitation of the chromosome 6-encoded dystrophin-related protein in normal and pathological human muscle. Journal of Neuropathology and Experimental Neurology. 52: 119-28. PMID 8440993 DOI: 10.1097/00005072-199303000-00004  0.324
1993 Hirst MC, Knight SJ, Christodoulou Z, Grewal PK, Fryns JP, Davies KE. Origins of the fragile X syndrome mutation. Journal of Medical Genetics. 30: 647-50. PMID 8411050 DOI: 10.1136/Jmg.30.8.647  0.348
1993 Thompson TG, Morrison KE, Kleyn P, Bengtsson U, Gilliam TC, Davies KE, Wasmuth JJ, McPherson JD. High resolution physical map of the region surrounding the spinal muscular atrophy gene. Human Molecular Genetics. 2: 1169-76. PMID 8401498 DOI: 10.1093/Hmg/2.8.1169  0.332
1993 Tinsley JM, Blake DJ, Pearce M, Knight AE, Kendrick-Jones J, Davies KE. Dystrophin and related proteins. Current Opinion in Genetics & Development. 3: 484-90. PMID 8353425 DOI: 10.1016/0959-437X(93)90124-8  0.334
1993 Love DR, Byth BC, Tinsley JM, Blake DJ, Davies KE. Dystrophin and dystrophin-related proteins: a review of protein and RNA studies. Neuromuscular Disorders : Nmd. 3: 5-21. PMID 8329888 DOI: 10.1016/0960-8966(93)90037-K  0.358
1993 Pearce M, Blake DJ, Tinsley JM, Byth BC, Campbell L, Monaco AP, Davies KE. The utrophin and dystrophin genes share similarities in genomic structure. Human Molecular Genetics. 2: 1765-72. PMID 8281135 DOI: 10.1093/Hmg/2.11.1765  0.349
1993 Tinsley JM, Davies KE. Utrophin: a potential replacement for dystrophin? Neuromuscular Disorders : Nmd. 3: 537-9. PMID 8186707 DOI: 10.1016/0960-8966(93)90111-V  0.351
1993 Schofield J, Houzelstein D, Davies K, Buckingham M, Edwards YH. Expression of the dystrophin‐related protein (utrophin) gene during mouse embryogenesis Developmental Dynamics. 198: 254-264. PMID 8130373 DOI: 10.1002/Aja.1001980403  0.345
1993 Glass IA, Good P, Coleman MP, Fullwood P, Giles MG, Lindsay S, Nemeth AH, Davies KE, Willshaw HA, Fielder A. Genetic mapping of a cone and rod dysfunction (Aland Island eye disease) to the proximal short arm of the human X chromosome. Journal of Medical Genetics. 30: 1044-50. PMID 7907666 DOI: 10.1136/Jmg.30.12.1044  0.328
1992 Lindsay S, Thiselton DL, Bateman JB, Ngo JT, Sparkes RS, Coleman M, Davies KE, Bhattacharya SS. Localisation of the gene for Norrie disease to between DXS7 and DXS426 on Xp. Human Genetics. 88: 349-50. PMID 1733838 DOI: 10.1007/Bf00197273  0.315
1992 Dunckley MG, Love DR, Davies KE, Walsh FS, Morris GE, Dickson G. Retroviral-mediated transfer of a dystrophin minigene into mdx mouse myoblasts in vitro. Febs Letters. 296: 128-34. PMID 1733767 DOI: 10.1016/0014-5793(92)80363-L  0.383
1992 Hirst MC, Knight SM, Nakahori Y, Roche A, Davies KE. Molecular analysis of the fragile X syndrome. Journal of Inherited Metabolic Disease. 15: 532-8. PMID 1528014 DOI: 10.1007/BF01799612  0.335
1992 Helliwell TR, Man NT, Morris GE, Davies KE. The dystrophin-related protein, utrophin, is expressed on the sarcolemma of regenerating human skeletal muscle fibres in dystrophies and inflammatory myopathies. Neuromuscular Disorders : Nmd. 2: 177-84. PMID 1483043 DOI: 10.1016/0960-8966(92)90004-P  0.309
1992 Byth BC, Love DR, Murray JC, Davies KE. Localization of two new DNA markers on the linkage map of human chromosome 6q. Cytogenetics and Cell Genetics. 60: 216-8. PMID 1354595 DOI: 10.1159/000133342  0.315
1992 Wöhrle D, Hirst MC, Kennerknecht I, Davies KE, Steinbach P. Genotype mosaicism in fragile X fetal tissues. Human Genetics. 89: 114-6. PMID 1349561 DOI: 10.1007/BF00207057  0.33
1992 Hirst MC, Knight SJ, Bell MV, Super M, Davies KE. The fragile X syndrome. Clinical Science (London, England : 1979). 83: 255-64. PMID 1327643 DOI: 10.1042/Cs0830255  0.312
1992 Chen ZY, Sims KB, Coleman M, Donnai D, Monaco A, Breakefield XO, Davies KE, Craig IW. Characterization of a YAC containing part or all of the Norrie disease locus. Human Molecular Genetics. 1: 161-4. PMID 1303171 DOI: 10.1093/Hmg/1.3.161  0.314
1992 Walker AP, Chelly J, Love DR, Brush YI, Récan D, Chaussain JL, Oley CA, Connor JM, Yates J, Price DA, Super M, Bottani A, Steinman B, Kaplan JC, Davies KE, et al. A YAC contig in Xp21 containing the adrenal hypoplasia congenita and glycerol kinase deficiency genes Human Molecular Genetics. 1: 579-585. PMID 1301166 DOI: 10.1093/Hmg/1.8.579  0.322
1992 Blake DJ, Love DR, Tinsley J, Morris GE, Turley H, Gatter K, Dickson G, Edwards YH, Davies KE. Characterization of a 4.8kb transcript from the Duchenne muscular dystrophy locus expressed in Schwannoma cells. Human Molecular Genetics. 1: 103-9. PMID 1301145 DOI: 10.1093/hmg/1.2.103  0.346
1992 Wells DJ, Wells KE, Walsh FS, Davies KE, Goldspink G, Love DR, Chan-Thomas P, Dunckley MG, Piper T, Dickson G. Human dystrophin expression corrects the myopathic phenotype in transgenic mdx mice. Human Molecular Genetics. 1: 35-40. PMID 1301134 DOI: 10.1093/Hmg/1.1.35  0.398
1991 Love DR, England SB, Speer A, Marsden RF, Bloomfield JF, Roche AL, Cross GS, Mountford RC, Smith TJ, Davies KE. Sequences of junction fragments in the deletion-prone region of the dystrophin gene. Genomics. 10: 57-67. PMID 2045110 DOI: 10.1016/0888-7543(91)90484-V  0.358
1991 Love DR, Morris GE, Ellis JM, Fairbrother U, Marsden RF, Bloomfield JF, Edwards YH, Slater CP, Parry DJ, Davies KE. Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse. Proceedings of the National Academy of Sciences of the United States of America. 88: 3243-7. PMID 2014247 DOI: 10.1073/Pnas.88.8.3243  0.38
1991 Dickson G, Love DR, Davies KE, Wells KE, Piper TA, Walsh FS. Human dystrophin gene transfer: production and expression of a functional recombinant DNA-based gene. Human Genetics. 88: 53-8. PMID 1959926 DOI: 10.1007/Bf00204929  0.393
1991 Nakahori Y, Knight SJL, Holland J, Schwartz C, Roche A, Tarleton J, Wong S, Flint TJ, Froster-Iskenius U, Bentley D, Davies KE, Hirst MC. Molecular heterogeneity of the fragile X syndrome. Nucleic Acids Research. 19: 4355-4359. PMID 1886762 DOI: 10.1093/Nar/19.16.4355  0.317
1991 Acsadi G, Dickson G, Love DR, Jani A, Walsh FS, Gurusinghe A, Wolff JA, Davies KE. Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs. Nature. 352: 815-8. PMID 1881437 DOI: 10.1038/352815A0  0.38
1991 Davies KE, Thomas NH, Daniels RJ, Dubowitz V. Molecular studies of spinal muscular atrophy. Neuromuscular Disorders : Nmd. 1: 83-5. PMID 1822785 DOI: 10.1016/0960-8966(91)90053-U  0.41
1991 Coleman MP, Murray JC, Willard HF, Nolan KF, Reid KB, Blake DJ, Lindsay S, Bhattacharya SS, Wright A, Davies KE. Genetic and physical mapping around the properdin P gene. Genomics. 11: 991-6. PMID 1783405 DOI: 10.1016/0888-7543(91)90024-9  0.323
1991 Love DR, Flint TJ, Genet SA, Middleton-Price HR, Davies KE. Becker muscular dystrophy patient with a large intragenic dystrophin deletion: implications for functional minigenes and gene therapy. Journal of Medical Genetics. 28: 860-4. PMID 1757963 DOI: 10.1136/Jmg.28.12.860  0.394
1991 Nguyen TM, Ellis JM, Love DR, Davies KE, Gatter KC, Dickson G, Morris GE. Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: presence at neuromuscular junctions, in the sarcolemma of dystrophic skeletal muscle, in vascular and other smooth muscles, and in proliferating brain cell lines. The Journal of Cell Biology. 115: 1695-700. PMID 1757469 DOI: 10.1083/Jcb.115.6.1695  0.328
1990 England SB, Nicholson LVB, Johnson MA, Forrest SM, Love DR, Zubrzycka-Gaarn EE, Bulman DE, Harris JB, Davies KE. Very mild muscular dystrophy associated with the deletion of 46% of dystrophin Nature. 343: 180-182. PMID 2404210 DOI: 10.1038/343180A0  0.407
1990 Brzustowicz LM, Lehner T, Castilla LH, Penchaszadeh GK, Wilhelmsen KC, Daniels R, Davies KE, Leppert M, Ziter F, Wood D, Dubowitz V, Zerres K, Hausmanowa-Petrusewicz I, Ott J, Munsat TL, et al. Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1 1.2-13.3 Nature. 344: 540-541. PMID 2320125 DOI: 10.1038/344540A0  0.344
1990 Munsat TL, Skerry L, Korf B, Pober B, Schapira Y, Gascon GG, Al-Rajeh SM, Dubowitz V, Davies K, Brzustowicz LM, Penchaszadeh GK, Gilliam TC. Phenotypic heterogeneity of spinal muscular atrophy mapping to chromosome 5q11.2-13.3 (SMA 5q) Neurology. 40: 1831-1836. PMID 2247230 DOI: 10.1212/WNL.40.12.1831  0.336
1990 Love DR, Flint TJ, Marsden RF, Bloomfield JF, Daniels RJ, Forrest SM, Gabrielli O, Giorgi P, Novelli G, Davies KE. Characterization of deletions in the dystrophin gene giving mild phenotypes American Journal of Medical Genetics. 37: 136-142. PMID 2240031 DOI: 10.1002/ajmg.1320370132  0.389
1990 Buckle VJ, Guenet JL, Simon-Chazottes D, Love DR, Davies KE. Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus Human Genetics. 85: 324-326. PMID 2203673 DOI: 10.1007/BF00206755  0.322
1990 Passos-Bueno MR, Rapaport D, Love D, Flint T, Bortolini ER, Zatz M, Davies KE. Screening of deletions in the dystrophin gene with the cDNA probes Cf23a, Cf56a, and Cf115. Journal of Medical Genetics. 27: 145-50. PMID 2182872 DOI: 10.1136/jmg.27.3.145  0.337
1990 Love DR, Bloomfield JF, Kenwrick SJ, Yates JRW, Davies KE. Physical mapping distal to the DMD locus Genomics. 8: 106-112. PMID 2081587 DOI: 10.1016/0888-7543(90)90231-I  0.344
1990 Thakker RV, Davies KE, Read AP, Tippett P, Wooding C, Flint T, Woob S, Kruse TA, Whyte MP, O'Riordan JLH. Linkage analysis of two cloned DNA sequences, DXS197 and DXS207, in hypophosphatemic rickets families Genomics. 8: 189-193. PMID 1979046 DOI: 10.1016/0888-7543(90)90271-U  0.306
1990 Thakker RV, Davies KE, Whyte MP, Wooding C, O'Riordan JLH. Mapping the gene causing X-linked recessive idiopathic hypoparathyroidism to Xq26-Xq27 by linkage studies Journal of Clinical Investigation. 86: 40-45. PMID 1973175 DOI: 10.1172/JCI114712  0.352
1989 Willard HF, Durfy SJ, Mahtani MM, Dorkins H, Davies KE, Williams BR. Regional localization of the TIMP gene on the human X chromosome. Extension of a conserved synteny and linkage group on proximal Xp. Human Genetics. 81: 234-8. PMID 2921031 DOI: 10.1007/Bf00278995  0.32
1989 Speer A, Spiegler AW, Hanke R, Grade K, Giertler U, Schieck J, Forrest S, Davies KE, Neumann R, Bollmann R. Possibilities and limitation of prenatal diagnosis and carrier determination for Duchenne and Becker muscular dystrophy using cDNA probes. Journal of Medical Genetics. 26: 1-5. PMID 2918522 DOI: 10.1136/jmg.26.1.1  0.304
1989 Love DR, Forrest SM, Smith TJ, England S, Flint T, Davies KE, Speer A. Molecular analysis of duschenne and becker muscular dystrophies British Medical Bulletin. 45: 659-680. PMID 2688822 DOI: 10.1093/OXFORDJOURNALS.BMB.A072351  0.385
1989 Thakker RV, Davies KE, O'Riordan JL. Gene mapping of mineral metabolic disorders. Journal of Inherited Metabolic Disease. 231-46. PMID 2681997 DOI: 10.1007/BF01799298  0.338
1989 Suthers GK, Callen DF, Hyland VJ, Kozman HM, Baker E, Eyre H, Harper PS, Roberts SH, Hors-Cayla MC, Davies KE, Bell MV, Sutherland GR. A new dna marker tightly linked to the fragile x locus (fraxa) Science. 246: 1298-1300. PMID 2573953 DOI: 10.1126/Science.2573953  0.315
1989 Love DR, Hill DF, Dickson G, Spurr NK, Byth BC, Marsden RF, Walsh FS, Edwards YH, Davies KE. An autosomal transcript in skeletal muscle with homology to dystrophin. Nature. 339: 55-8. PMID 2541343 DOI: 10.1038/339055A0  0.336
1988 Forrest SM, Cross GS, Flint T, Speer A, Robson KJH, Davies KE. Further studies of gene deletions that cause Duchenne and Becker muscular dystrophies Genomics. 2: 109-114. PMID 3410474 DOI: 10.1016/0888-7543(88)90091-2  0.355
1988 Kenwrick SJ, Smith TJ, England S, Collins F, Davies KE. Localisation of the endpoints of deletions in the 5′ region of the duchenne gene using a sequence isolated by chromosome jumping Nucleic Acids Research. 16: 1305-1317. PMID 3347492 DOI: 10.1093/Nar/16.4.1305  0.336
1988 Davies KE, Kenwrick SJ, Patterson MN, Smith TJ, Forrest SM, Dorkins HR, Cross GS, England SB. Molecular analysis of muscular dystrophy. Journal of Muscle Research and Cell Motility. 9: 1-8. PMID 3292577 DOI: 10.1007/BF01682143  0.336
1988 Cavanna JS, Coulton G, Morgan JE, Brockdorff N, Forrest SM, Davies KE, Brown SD. Molecular and genetic mapping of the mouse mdx locus. Genomics. 3: 337-41. PMID 3243547 DOI: 10.1016/0888-7543(88)90124-3  0.37
1988 Read AP, Mountford RC, Forrest SM, Kenwrick SJ, Davies KE, Harris R. Patterns of exon deletions in Duchenne and Becker muscular dystrophy Human Genetics. 80: 152-156. PMID 3169738 DOI: 10.1007/BF00702859  0.335
1988 Davies KE, Smith TJ, Bundey S, Read AP, Flint T, Bell M, Speer A. Mild and severe muscular dystrophy associated with deletions in Xp21 of the human X chromosome Journal of Medical Genetics. 25: 9-13. PMID 3162536 DOI: 10.1136/jmg.25.1.9  0.371
1988 Davies KE, Patterson MN, Kenwrick SJ, Bell MV, Sloan HR, Westman JA, Elsas LJ, Mahan J. Fine mapping of glycerol kinase deficiency and congenital adrenal hypoplasia within Xp21 on the short arm of the human X chromosome. American Journal of Medical Genetics. 29: 557-64. PMID 2837087 DOI: 10.1002/AJMG.1320290313  0.313
1987 Davies KE, Gusella JF, Tsui LC, Williamson R, Page DC, Ferguson-Smith MA. Valuable libraries. Nature. 326: 124. PMID 3821885 DOI: 10.1038/326124e0  0.319
1987 Smith TJ, Forrest SM, Cross GS, Davies KE. Duchenne and becker muscular dystrophy mutations: Analysis using 2.6 kb of muscle cDNA from the 5′ end of the gene Nucleic Acids Research. 15: 9761-9769. PMID 3697082 DOI: 10.1093/nar/15.23.9761  0.369
1987 Davies KE, Robson KJ. Molecular analysis of human monogenic diseases Bioessays. 6: 247-253. PMID 3619885 DOI: 10.1002/Bies.950060602  0.399
1987 Reeders ST, Breuning MH, Ryynanen MA, Wright AF, Davies KE, King AW, Watson ML, Weatherall DJ. A study of genetic linkage heterogeneity in adult polycystic kidney disease. Human Genetics. 76: 348-51. PMID 3610154 DOI: 10.1007/BF00272443  0.317
1987 Brockdorff N, Cross GS, Cavanna JS, Fisher EM, Lyon MF, Davies KE, Brown SD. The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome. Nature. 328: 166-8. PMID 3600793 DOI: 10.1038/328166A0  0.37
1987 Smith TJ, Wilson L, Kenwrick SJ, Forrest SM, Speer A, Coutelle C, Davies KE. Isolation of a conserved sequence deleted in Duchenne muscular dystrophy patients. Nucleic Acids Research. 15: 2167-74. PMID 3562224 DOI: 10.1093/NAR/15.5.2167  0.303
1987 Davies KE, Forrest S, Smith T, Kenwrick S, Ball S, Dorkins H, Patterson M. Molecular analysis of human muscular dystrophies Muscle & Nerve. 10: 191-199. PMID 2882417 DOI: 10.1002/Mus.880100302  0.365
1987 Thakker RV, Read AP, Davies KE, Whyte MP, Weksberg R, Glorieux F, Davies M, Mountford RC, Harris R, King A, Kim GS, Fraser D, Kooh SW, O'Riordan JLH. Bridging markers defining the map position of X linked hypophosphataemic rickets Journal of Medical Genetics. 24: 756-760. PMID 2828625 DOI: 10.1136/jmg.24.12.756  0.311
1987 Forrest SM, Cross GS, Speer A, Gardner-Medwin D, Burn J, Davies KE. Preferential deletion of exons in Duchenne and Becker muscular dystrophies. Nature. 329: 638-40. PMID 2821406 DOI: 10.1038/329638a0  0.369
1987 Robbins TP, Scambler PJ, Davies KE, Williamson R. An anonymous clone E9pl (D4S112) localised to 4q26-qter detects an Msp I RFLP. Nucleic Acids Research. 15: 8122. PMID 2444927 DOI: 10.1093/nar/15.19.8122  0.324
1987 Cross GS, Speer A, Rosenthal A, Forrest SM, Smith TJ, Edwards Y, Flint T, Hill D, Davies KE. Deletions of fetal and adult muscle cDNA in Duchenne and Becker muscular dystrophy patients. The Embo Journal. 6: 3277-3283. DOI: 10.1002/j.1460-2075.1987.tb02646.x  0.322
1986 Fischbeck KH, Ionasescu V, Ritter AW, Ionasescu R, Davies K, Ball S, Bosch P, Burns T, Hausmanowa-Petrusewicz I, Borkowska J. Localization of the gene for X-linked spinal muscular atrophy. Neurology. 36: 1595-8. PMID 3466055 DOI: 10.1212/Wnl.36.12.1595  0.335
1986 Kenwrick S, Ionasescu V, Ionasescu G, Searby C, King A, Dubowitz M, Davies KE. Linkage studies of X-linked recessive spastic paraplegia using DNA probes. Human Genetics. 73: 264-6. PMID 3460961 DOI: 10.1007/BF00401241  0.303
1986 Farrall M, Scambler P, Klinger KW, Davies K, Worrall C, Williamson R, Wainwright B. Cystic fibrosis carrier detection using a linked gene probe. Journal of Medical Genetics. 23: 295-299. PMID 3018247 DOI: 10.1136/Jmg.23.4.295  0.3
1986 Schwartz M, Christensen E, Christensen NC, Skovby F, Davies KE, Old JM. Detection and exclusion of carriers of ornithine transcarbamylase deficiency by RFLP analysis. Clinical Genetics. 29: 449-52. PMID 3017613 DOI: 10.1111/j.1399-0004.1986.tb00520.x  0.324
1986 Pembrey ME, Old JM, Leonard JV, Rodeck CH, Warren R, Davies KE. Prenatal diagnosis of ornithine carbamoyl transferase deficiency using a gene specific probe. Journal of Medical Genetics. 22: 462-5. PMID 3001312 DOI: 10.1136/jmg.22.6.462  0.327
1986 Davies KE, Williamson R. Towards a complete linkage map of the human X chromosome. Horizons in Biochemistry and Biophysics. 8: 1-50. PMID 2875929  0.402
1986 Dunger DB, Pembrey M, Pearson P, Whitfield A, Davies KE, Lake B, Williams D, Dillon MJD. Deletion on the X chromosome detected by direct DNA analysis in one of two unrelated boys with glycerol kinase deficiency, adrenal hypoplasia, and Duchenne muscular dystrophy. The Lancet. 327: 585-587. PMID 2869305 DOI: 10.1016/S0140-6736(86)92811-4  0.316
1986 Thakker RV, Davies KE, Read AP, Glorieux F, O'Riordan JLH. LOCALISATION OF THE X-LINKED HYPOPHOSPHATAEMIC RICKETS GENE Pediatric Research. 20: 1185-1185. DOI: 10.1203/00006450-198611000-00068  0.331
1986 Davies KE. The elusive muscular dystrophy gene. Fifth Muscular Dystrophy Group Workshop on the X chromosome and muscular dystrophies, April 1986 Journal of Medical Genetics. 23: 482-483. DOI: 10.1136/jmg.23.6.482  0.314
1986 Pembrey ME, Winter RM, Davies KE. Fragile X mental retardation: current controversies Trends in Neurosciences. 9: 58-62. DOI: 10.1016/0166-2236(86)90021-4  0.345
1985 Davies KE, Speer A, Herrmann F, Spiegler AW, McGlade S, Hofker MH, Briand P, Hanke R, Schwartz M, Steinbicker V. Human X chromosome markers and Duchenne muscular dystrophy. Nucleic Acids Research. 13: 3419-26. PMID 3859837 DOI: 10.1093/NAR/13.10.3419  0.335
1985 Donald JA, Wallis SC, Kessling A, Tippett P, Robson EB, Ball S, Davies KE, Scambler P, Berg K, Heiberg A. Linkage relationships of the gene for apolipoprotein CII with loci on chromosome 19. Human Genetics. 69: 39-43. PMID 3855405 DOI: 10.1007/Bf00295527  0.329
1985 Davies KE, Briand P, Ionasescu V, Ionasescu G, Williamson R, Brown C, Cavard C, Cathelineau L. Gene for OTC: characterisation and linkage to Duchenne muscular dystrophy. Nucleic Acids Research. 13: 155-65. PMID 3839070 DOI: 10.1093/Nar/13.1.155  0.476
1985 Ball SP, Kenwrick SJ, Davies KE. The molecular genetics of human monogenic diseases Biotechnology and Genetic Engineering Reviews. 3: 275-309. PMID 3004535 DOI: 10.1080/02648725.1985.10647816  0.324
1985 Reeders ST, Breuning MH, Davies KE, Nicholls RD, Jarman AP, Higgs DR, Pearson PL, Weatherall DJ. A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature. 317: 542-4. PMID 2995836 DOI: 10.1038/317542a0  0.317
1985 Davies KE, Mattei MG, Mattei JF, Veenema H, McGlade S, Harper K, Tommerup N, Nielsen KB, Mikkelsen M, Beighton P, Drayna D, White R, Pembrey ME. Linkage studies of X-linked mental retardation: high frequency of recombination in the telomeric region of the human X chromosome (fragile site/linkage/recombination/X chromosome). Human Genetics. 70: 249-255. PMID 2991115 DOI: 10.1007/Bf00273451  0.31
1985 Ingle C, Williamson R, de la Chapelle A, Herva RR, Haapala K, Bates G, Willard HF, Pearson P, Davies KE. Mapping DNA sequences in a human X-chromosome deletion which extends across the region of the Duchenne muscular dystrophy mutation. American Journal of Human Genetics. 37: 451-62. PMID 2988331  0.397
1985 Scambler P, Robbins T, Gilliam C, Boylston A, Tippett P, Williamson R, Davies KE. Linkage studies between polymorphic markers on chromosome 4 and cystic fibrosis. Human Genetics. 69: 250-4. PMID 2984105 DOI: 10.1007/Bf00293035  0.479
1985 Bakker E, Hofker MH, Goor N, Mandel JL, Wrogemann K, Davies KE, Kunkel LM, Willard HF, Fenton WA, Sandkuyl L. Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs. Lancet (London, England). 1: 655-8. PMID 2858615 DOI: 10.1016/S0140-6736(85)91325-X  0.305
1985 Old JM, Briand PL, Purvis-Smith S, Howard NJ, Wilcken B, Hammond J, Pearson P, Cathelineau L, Williamson R, Davies KE. Prenatal exclusion of ornithine transcarbamylase deficiency by direct gene analysis. Lancet (London, England). 1: 73-5. PMID 2857026 DOI: 10.1016/S0140-6736(85)91966-X  0.505
1984 Pembrey ME, Davies KE, Winter RM, Elles RG, Williamson R, Fazzone TA, Walker C. Clinical use of DNA markers linked to the gene for Duchenne muscular dystrophy. Archives of Disease in Childhood. 59: 208-16. PMID 6585184 DOI: 10.1136/Adc.59.3.208  0.496
1984 Hartley DA, Davies KE, Drayna D, White RL, Williamson R. A cytological map of the human X chromosome--evidence for non-random recombination. Nucleic Acids Research. 12: 5277-85. PMID 6547776 DOI: 10.1093/nar/12.13.5277  0.465
1984 Williamson R, Davies KE, Donald J, Gilliam C, Wallis S, Humphries S. The implications of genetic variation in human pathology. Biochemical Society Symposium. 49: 183-8. PMID 6400491  0.422
1984 Drayna D, Davies K, Hartley D, Mandel JL, Camerino G, Williamson R, White R. Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 81: 2836-2839. PMID 6326147 DOI: 10.1073/Pnas.81.9.2836  0.468
1984 Wieacker P, Davies KE, Cooke HJ, Pearson PL, Williamson R, Bhattacharya S, Zimmer J, Ropers HH. Toward a complete linkage map of the human X chromosome: regional assignment of 16 cloned single-copy DNA sequences employing a panel of somatic cell hybrids. American Journal of Human Genetics. 36: 265-76. PMID 6324578  0.402
1984 Davies KE, Harper K, Bonthron D, Krumlauf R, Polkey A, Pembrey ME, Williamson R. Use of a chromosome 21 cloned DNA probe for the analysis of non-disjunction in Down syndrome. Human Genetics. 66: 54-6. PMID 6230306 DOI: 10.1007/Bf00275186  0.46
1984 Gilliam TC, Scambler P, Robbins T, Ingle C, Williamson R, Davies KE. The positions of three restriction fragment length polymorphisms on chromosome 4 relative to known genetic markers. Human Genetics. 68: 154-8. PMID 6094335 DOI: 10.1007/Bf00279306  0.451
1983 Wieacker P, Wienker TF, Dallapiccola B, Bender K, Davies KE, Ropers HH. Linkage relationships between Retinoschisis, Xg, and a cloned DNA sequence from the distal short arm of the X chromosome. Human Genetics. 64: 143-5. PMID 6885047 DOI: 10.1007/Bf00327111  0.309
1983 Harper PS, O'Brien T, Murray JM, Davies KE, Pearson P, Williamson R. The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy. Journal of Medical Genetics. 20: 252-4. PMID 6684693 DOI: 10.1136/Jmg.20.4.252  0.453
1983 O'Brien T, Harper PS, Davies KE, Murray JM, Sarfarazi M, Williamson R. Absence of genetic heterogeneity in Duchenne muscular dystrophy shown by a linkage study using two cloned DNA sequences. Journal of Medical Genetics. 20: 249-51. PMID 6684692 DOI: 10.1136/Jmg.20.4.249  0.47
1983 Davies KE, Jackson J, Williamson R, Harper PS, Ball S, Sarfarazi M, Meredith L, Fey G. Linkage analysis of myotonic dystrophy and sequences on chromosome 19 using a cloned complement 3 gene probe. Journal of Medical Genetics. 20: 259-63. PMID 6620325 DOI: 10.1136/Jmg.20.4.259  0.469
1983 Davies KE, Taylor P, Müller CR. Sex chromosome-specific DNA sequences Differentiation. 23. PMID 6444174 DOI: 10.1007/978-3-642-69150-8_8  0.327
1983 Sarfarazi M, Harper PS, Kingston HM, Murray JM, O'Brien T, Davies KE, Williamson R, Tippett P, Sanger R. Genetic linkage relationship between the Xg blood group system and two X chromosome DNA polymorphisms in families with Duchenne and Becker muscular dystrophy. Human Genetics. 65: 169-71. PMID 6317539 DOI: 10.1007/Bf00286656  0.458
1983 Davies KE, Pearson PL, Harper PS, Murray JM, O'Brien T, Sarfarazi M, Williamson R. Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy locus on the short arm of the human X chromosome. Nucleic Acids Research. 11: 2303-12. PMID 6304647 DOI: 10.1093/Nar/11.8.2303  0.484
1983 Kingston HM, Harper PS, Pearson PL, Davies KE, Williamson R, Page D. Localisation of gene for Becker muscular dystrophy. Lancet (London, England). 2: 1200. PMID 6139558 DOI: 10.1016/S0140-6736(83)91252-7  0.486
1983 Davies KE, Harper PS, Williamson R. Cloned gene probes for carrier detection in muscular dystrophy. Lancet (London, England). 2: 108. PMID 6134944 DOI: 10.1016/S0140-6736(83)90095-8  0.47
1983 Davies KE, Gilliam TC, Williamson R. Cystic fibrosis is not caused by a defect in the gene coding for human complement C3. Molecular Biology & Medicine. 1: 185-90. PMID 6094950  0.422
1982 Murray JM, Davies KE, Harper PS, Meredith L, Mueller CR, Williamson R. Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy. Nature. 300: 69-71. PMID 6982420 DOI: 10.1038/300069A0  0.483
1982 Hill ME, Davies KE, Harper P, Williamson R. The Mendelian inheritance of a human X chromosome-specific DNA sequence polymorphism and its use in linkage studies of genetic disease. Human Genetics. 60: 222-6. PMID 6286461 DOI: 10.1007/Bf00303007  0.477
1981 Davies KE, Young BD, Elles RG, Hill ME, Williamson R. Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry. Nature. 293: 374-6. PMID 6456416 DOI: 10.1038/293374A0  0.465
1981 Hill MEE, Ellis RG, Davies KE, Williamson R. Cloning Of A Library Representative Of The Human X-Chromosome Biochemical Society Transactions. 9. DOI: 10.1042/Bst009130Pe  0.441
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