| Year |
Citation |
Score |
| 2020 |
Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Smolensky L, Amondikar N, Hutten SJ, Frasier M, Nguyen KH, ... ... Simon DK, et al. Differences in the Presentation and Progression of Parkinson's Disease by Sex. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33002231 DOI: 10.1002/mds.28312 |
0.361 |
|
| 2020 |
Cutillo G, Simon DK, Eleuteri S. VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology. Neurobiology of Disease. 145: 105056. PMID 32853677 DOI: 10.1016/j.nbd.2020.105056 |
0.369 |
|
| 2020 |
Simon DK, Tanner CM, Brundin P. Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology. Clinics in Geriatric Medicine. 36: 1-12. PMID 31733690 DOI: 10.1016/j.cger.2019.08.002 |
0.33 |
|
| 2019 |
Iwaki H, Blauwendraat C, Leonard HL, Kim JJ, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, ... ... Simon DK, et al. Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31505070 DOI: 10.1002/Mds.27845 |
0.441 |
|
| 2019 |
Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, et al. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 92: 329-337. PMID 30745444 DOI: 10.1212/Wnl.0000000000006926 |
0.301 |
|
| 2018 |
Quansah E, Peelaerts W, Langston JW, Simon DK, Colca J, Brundin P. Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration. Molecular Neurodegeneration. 13: 28. PMID 29793507 DOI: 10.1186/s13024-018-0260-x |
0.319 |
|
| 2017 |
Gibbons CH, Simon DK, Huang M, Tilley B, Aminoff MJ, Bainbridge JL, Brodsky M, Freeman R, Goudreau J, Hamill RW, Luo ST, Singer C, Videnovic A, Bodis-Wollner I, Wong PS, et al. Autonomic and electrocardiographic findings in Parkinson's disease. Autonomic Neuroscience : Basic & Clinical. PMID 28506500 DOI: 10.1016/J.Autneu.2017.04.002 |
0.324 |
|
| 2017 |
Chou KL, Elm JJ, Wielinski CL, Simon DK, Aminoff MJ, Christine CW, Liang GS, Hauser RA, Sudarsky L, Umeh CC, Voss T, Juncos J, Fang JY, Boyd JT, Bodis-Wollner I, et al. Factors associated with falling in early, treated Parkinson's disease: The NET-PD LS1 cohort. Journal of the Neurological Sciences. 377: 137-143. PMID 28477684 DOI: 10.1016/J.Jns.2017.04.011 |
0.327 |
|
| 2017 |
Simon DK, Matott JC, Espinosa J, Abraham NA. Mitochondrial DNA mutations in Parkinson's disease brain. Acta Neuropathologica Communications. 5: 33. PMID 28454551 DOI: 10.1186/s40478-017-0433-9 |
0.352 |
|
| 2017 |
Simon DK, Wu C, Tilley BC, Lohmann K, Klein C, Payami H, Wills AM, Aminoff MJ, Bainbridge J, Dewey R, Hauser RA, Schaake S, Schneider JS, Sharma S, Singer C, et al. Caffeine, creatine, GRIN2A and Parkinson's disease progression. Journal of the Neurological Sciences. 375: 355-359. PMID 28320167 DOI: 10.1016/J.Jns.2017.02.032 |
0.325 |
|
| 2017 |
Espay AJ, Schwarzschild MA, Tanner CM, Fernandez HH, Simon DK, Leverenz JB, Merola A, Chen-Plotkin A, Brundin P, Kauffman MA, Erro R, Kieburtz K, Woo D, Macklin EA, Standaert DG, et al. Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28233927 DOI: 10.1002/Mds.26913 |
0.333 |
|
| 2016 |
Clark-Matott J, Graebner AK, Bass CE, Simon DK. 376. Overexpression of Pitx3 in the SNpc and Protection from MPTP Toxicity Molecular Therapy. 24: S150. DOI: 10.1016/S1525-0016(16)33185-9 |
0.336 |
|
| 2015 |
Taylor KM, Saint-Hilaire MH, Sudarsky L, Simon DK, Hersh B, Sparrow D, Hu H, Weisskopf MG. Head injury at early ages is associated with risk of Parkinson's disease. Parkinsonism & Related Disorders. PMID 26725141 DOI: 10.1016/J.Parkreldis.2015.12.005 |
0.308 |
|
| 2015 |
Simon DK, Simuni T, Elm J, Clark-Matott J, Graebner AK, Baker L, Dunlop SR, Emborg M, Kamp C, Morgan JC, Ross GW, Sharma S, Ravina B. Peripheral Biomarkers of Parkinson's Disease Progression and Pioglitazone Effects. Journal of Parkinson's Disease. PMID 26444095 DOI: 10.3233/Jpd-150666 |
0.328 |
|
| 2015 |
Simon DK, Wu C, Tilley BC, Wills AM, Aminoff MJ, Bainbridge J, Hauser RA, Schneider JS, Sharma S, Singer C, Tanner CM, Truong D, Wong PS. Caffeine and Progression of Parkinson Disease: A Deleterious Interaction With Creatine. Clinical Neuropharmacology. 38: 163-9. PMID 26366971 DOI: 10.1097/Wnf.0000000000000102 |
0.322 |
|
| 2015 |
Clark-Matott J, Saleem A, Dai Y, Shurubor Y, Ma X, Safdar A, Beal MF, Tarnopolsky M, Simon DK. Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain. Neurobiology of Aging. 36: 2972-83. PMID 26294258 DOI: 10.1016/J.Neurobiolaging.2015.07.020 |
0.517 |
|
| 2014 |
Dai Y, Clark J, Zheng K, Kujoth GC, Prolla TA, Simon DK. Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicology and Teratology. 46: 62-7. PMID 25450660 DOI: 10.1016/J.Ntt.2014.10.004 |
0.744 |
|
| 2014 |
Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, ... ... Simon DK, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. Jama Neurology. 71: 543-52. PMID 24664227 DOI: 10.1001/Jamaneurol.2014.131 |
0.464 |
|
| 2014 |
Dai Y, Zheng K, Clark J, Swerdlow RH, Pulst SM, Sutton JP, Shinobu LA, Simon DK. Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation. Human Molecular Genetics. 23: 637-47. PMID 24101601 DOI: 10.1093/Hmg/Ddt450 |
0.773 |
|
| 2013 |
Dai Y, Kiselak T, Clark J, Clore E, Zheng K, Cheng A, Kujoth GC, Prolla TA, Maratos-Flier E, Simon DK. Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion. 13: 282-91. PMID 23542163 DOI: 10.1016/J.Mito.2013.03.006 |
0.749 |
|
| 2012 |
Clark J, Silvaggi JM, Kiselak T, Zheng K, Clore EL, Dai Y, Bass CE, Simon DK. Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf. Plos One. 7: e48925. PMID 23145024 DOI: 10.1371/Journal.Pone.0048925 |
0.752 |
|
| 2012 |
Göbel A, Macklin EA, Winkler S, Betensky RA, Klein C, Lohmann K, Simon DK. Genetic risk factors in Parkinson's disease: single gene effects and interactions of genotypes. Journal of Neurology. 259: 2503-5. PMID 22878430 DOI: 10.1007/s00415-012-6623-2 |
0.322 |
|
| 2012 |
Kumar KR, Weissbach A, Heldmann M, Kasten M, Tunc S, Sue CM, Svetel M, Kosti? VS, Segura-Aguilar J, Ramirez A, Simon DK, Vieregge P, Münte TF, Hagenah J, Klein C, et al. Frequency of the D620N mutation in VPS35 in Parkinson disease. Archives of Neurology. 69: 1360-4. PMID 22801713 DOI: 10.1001/archneurol.2011.3367 |
0.368 |
|
| 2012 |
Lin MT, Cantuti-Castelvetri I, Zheng K, Jackson KE, Tan YB, Arzberger T, Lees AJ, Betensky RA, Beal MF, Simon DK. Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease. Annals of Neurology. 71: 850-4. PMID 22718549 DOI: 10.1002/Ana.23568 |
0.637 |
|
| 2011 |
Simon DK, Chu CT, Swerdlow RH. Mitochondria and Parkinson's disease. Parkinson's Disease. 2011: 261791. PMID 22973533 DOI: 10.4061/2011/261791 |
0.358 |
|
| 2011 |
Clark J, Dai Y, Simon DK. Do somatic mitochondrial DNA mutations contribute to Parkinson's disease? Parkinson's Disease. 2011: 659694. PMID 21603185 DOI: 10.4061/2011/659694 |
0.754 |
|
| 2011 |
Clark J, Reddy S, Zheng K, Betensky RA, Simon DK. Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease. Bmc Medical Genetics. 12: 69. PMID 21595954 DOI: 10.1186/1471-2350-12-69 |
0.717 |
|
| 2010 |
Connolly BS, Feigenbaum AS, Robinson BH, Dipchand AI, Simon DK, Tarnopolsky MA. MELAS syndrome, cardiomyopathy, rhabdomyolysis, and autism associated with the A3260G mitochondrial DNA mutation. Biochemical and Biophysical Research Communications. 402: 443-7. PMID 20965148 DOI: 10.1016/j.bbrc.2010.10.060 |
0.347 |
|
| 2010 |
Clark J, Clore EL, Zheng K, Adame A, Masliah E, Simon DK. Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. Plos One. 5: e12333. PMID 20808797 DOI: 10.1371/journal.pone.0012333 |
0.745 |
|
| 2010 |
Weisskopf MG, Weuve J, Nie H, Saint-Hilaire MH, Sudarsky L, Simon DK, Hersh B, Schwartz J, Wright RO, Hu H. Association of cumulative lead exposure with Parkinson's disease. Environmental Health Perspectives. 118: 1609-13. PMID 20807691 DOI: 10.1289/Ehp.1002339 |
0.311 |
|
| 2010 |
Guo X, Kudryavtseva E, Bodyak N, Nicholas A, Dombrovsky I, Yang D, Kraytsberg Y, Simon DK, Khrapko K. Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse. Biochimica Et Biophysica Acta. 1797: 1159-62. PMID 20388490 DOI: 10.1016/j.bbabio.2010.04.005 |
0.352 |
|
| 2010 |
Simon DK, Pankratz N, Kissell DK, Pauciulo MW, Halter CA, Rudolph A, Pfeiffer RF, Nichols WC, Foroud T. Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease. Bmc Medical Genetics. 11: 53. PMID 20356410 DOI: 10.1186/1471-2350-11-53 |
0.373 |
|
| 2009 |
Kraytsberg Y, Simon DK, Turnbull DM, Khrapko K. Do mtDNA deletions drive premature aging in mtDNA mutator mice? Aging Cell. 8: 502-6. PMID 19416127 DOI: 10.1111/j.1474-9726.2009.00484.x |
0.362 |
|
| 2009 |
Xiao J, Bastian RW, Perlmutter JS, Racette BA, Tabbal SD, Karimi M, Paniello RC, Blitzer A, Batish SD, Wszolek ZK, Uitti RJ, Hedera P, Simon DK, Tarsy D, Truong DD, et al. High-throughput mutational analysis of TOR1A in primary dystonia. Bmc Medical Genetics. 10: 24. PMID 19284587 DOI: 10.1186/1471-2350-10-24 |
0.307 |
|
| 2009 |
Clark J, Simon DK. Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxidants & Redox Signaling. 11: 509-28. PMID 18717631 DOI: 10.1089/ARS.2008.2241 |
0.731 |
|
| 2008 |
Simon DK, Swearingen CJ, Hauser RA, Trugman JM, Aminoff MJ, Singer C, Truong D, Tilley BC. Caffeine and progression of Parkinson disease. Clinical Neuropharmacology. 31: 189-96. PMID 18670242 DOI: 10.1097/Wnf.0B013E31815A3F03 |
0.324 |
|
| 2007 |
Djarmati A, Guzvić M, Grünewald A, Lang AE, Pramstaller PP, Simon DK, Kaindl AM, Vieregge P, Nygren AO, Beetz C, Hedrich K, Klein C. Rapid and reliable detection of exon rearrangements in various movement disorders genes by multiplex ligation-dependent probe amplification. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1708-14. PMID 17674414 DOI: 10.1002/mds.21370 |
0.334 |
|
| 2007 |
Nichols WC, Marek DK, Pauciulo MW, Pankratz N, Halter CA, Rudolph A, Shults CW, Wojcieszek J, Foroud T, Shults C, Marshall F, Oakes D, Shinaman A, Marder K, Conneally PM, ... ... Simon D, et al. R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation Movement Disorders. 22: 254-257. PMID 17149721 DOI: 10.1002/Mds.21233 |
0.363 |
|
| 2006 |
Pankratz N, Pauciulo MW, Elsaesser VE, Marek DK, Halter CA, Rudolph A, Shults CW, Foroud T, Nichols WC, Shults C, Marshall F, Oakes D, Shinaman A, Marder K, Conneally PM, ... ... Simon D, et al. Mutations in LRRK2 other than G2019S are rare in a north-American based sample of familial Parkinson's didease Movement Disorders. 21: 2257-2260. PMID 17078063 DOI: 10.1002/Mds.21162 |
0.338 |
|
| 2005 |
Cantuti-Castelvetri I, Lin MT, Zheng K, Keller-McGandy CE, Betensky RA, Johns DR, Beal MF, Standaert DG, Simon DK. Somatic mitochondrial DNA mutations in single neurons and glia. Neurobiology of Aging. 26: 1343-55. PMID 16243605 DOI: 10.1016/J.Neurobiolaging.2004.11.008 |
0.611 |
|
| 2005 |
Lee J, Kim CH, Simon DK, Aminova LR, Andreyev AY, Kushnareva YE, Murphy AN, Lonze BE, Kim KS, Ginty DD, Ferrante RJ, Ryu H, Ratan RR. Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. The Journal of Biological Chemistry. 280: 40398-401. PMID 16207717 DOI: 10.1074/Jbc.C500140200 |
0.309 |
|
| 2005 |
Lin MT, Simon DK. No evidence for heritability of Parkinson disease in Swedish twins. Neurology. 64: 932; author reply 93. PMID 15753453 DOI: 10.1212/WNL.64.5.932 |
0.497 |
|
| 2004 |
Nichols WC, Uniacke SK, Pankratz N, Reed T, Simon DK, Halter C, Rudolph A, Shults CW, Conneally PM, Foroud T. Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 19: 649-55. PMID 15197702 DOI: 10.1002/Mds.20097 |
0.338 |
|
| 2004 |
Tarnopolsky MA, Simon DK, Roy BD, Chorneyko K, Lowther SA, Johns DR, Sandhu JK, Li Y, Sikorska M. Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutation. Muscle & Nerve. 29: 537-47. PMID 15052619 DOI: 10.1002/mus.20020 |
0.331 |
|
| 2004 |
Tarnopolsky MA, Bourgeois JM, Fu MH, Kataeva G, Shah J, Simon DK, Mahoney D, Johns D, MacKay N, Robinson BH. Novel SCO2 mutation (G1521A) presenting as a spinal muscular atrophy type I phenotype. American Journal of Medical Genetics. Part A. 125: 310-4. PMID 14994243 DOI: 10.1002/ajmg.a.20466 |
0.317 |
|
| 2004 |
Simon DK, Lin MT, Zheng L, Liu GJ, Ahn CH, Kim LM, Mauck WM, Twu F, Beal MF, Johns DR. Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease. Neurobiology of Aging. 25: 71-81. PMID 14675733 DOI: 10.1016/S0197-4580(03)00037-X |
0.63 |
|
| 2003 |
Simon DK, Friedman J, Breakefield XO, Jankovic J, Brin MF, Provias J, Bressman SB, Charness ME, Tarsy D, Johns DR, Tarnopolsky MA. A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia. Neurogenetics. 4: 199-205. PMID 12756609 DOI: 10.1007/s10048-003-0150-3 |
0.349 |
|
| 2003 |
Zheng K, Heydari B, Simon DK. A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease. Archives of Neurology. 60: 722-5. PMID 12756136 DOI: 10.1001/archneur.60.5.722 |
0.329 |
|
| 2002 |
Simon DK, Lin MT, Pascual-Leone A. "Nature versus nurture" and incompletely penetrant mutations. Journal of Neurology, Neurosurgery, and Psychiatry. 72: 686-9. PMID 12023405 DOI: 10.1136/Jnnp.72.6.686 |
0.49 |
|
| 2002 |
Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF. High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Human Molecular Genetics. 11: 133-45. PMID 11809722 DOI: 10.1093/Hmg/11.2.133 |
0.618 |
|
| 2001 |
Simon DK, Lin MT, Ahn CH, Liu GJ, Gibson GE, Beal MF, Johns DR. Low mutational burden of individual acquired mitochondrial DNA mutations in brain. Genomics. 73: 113-6. PMID 11352572 DOI: 10.1006/Geno.2001.6515 |
0.623 |
|
| 2000 |
Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology. 54: 703-9. PMID 10680807 DOI: 10.1212/Wnl.54.3.703 |
0.524 |
|
| 1999 |
Simon DK, Pulst SM, Sutton JP, Browne SE, Beal MF, Johns DR. Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation. Neurology. 53: 1787-93. PMID 10563629 DOI: 10.1212/Wnl.53.8.1787 |
0.634 |
|
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