| Year |
Citation |
Score |
| 2024 |
Fote GM, Eapen VV, Lim RG, Yu C, Salazar L, McClure NR, McKnight J, Nguyen TB, Heath MC, Lau AL, Villamil MA, Miramontes R, Kratter IH, Finkbeiner S, Reidling JC, et al. Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 121: e2319091121. PMID 39074279 DOI: 10.1073/pnas.2319091121 |
0.727 |
|
| 2023 |
Elia L, Herting B, Alijagic A, Buselli C, Wong L, Morrison G, Prado MA, Paulo JA, Gygi SP, Finley D, Finkbeiner S. Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis. Biorxiv : the Preprint Server For Biology. PMID 36712069 DOI: 10.1101/2023.01.18.524611 |
0.359 |
|
| 2020 |
Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Osorio Oliviera A, Wong JS, Daub AC, Giorgini F, Muchowski P, Finkbeiner S. Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nature Communications. 11: 1065. PMID 32081961 DOI: 10.1038/S41467-020-14582-9 |
0.32 |
|
| 2020 |
Elia LP, Reisine T, Alijagic A, Finkbeiner S. Approaches to develop therapeutics to treat frontotemporal dementia. Neuropharmacology. 166: 107948. PMID 31962288 DOI: 10.1016/J.Neuropharm.2020.107948 |
0.416 |
|
| 2019 |
Fang MY, Markmiller S, Vu AQ, Javaherian A, Dowdle WE, Jolivet P, Bushway PJ, Castello NA, Baral A, Chan MY, Linsley JW, Linsley D, Mercola M, Finkbeiner S, Lecuyer E, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. PMID 31272829 DOI: 10.1016/J.Neuron.2019.05.048 |
0.336 |
|
| 2019 |
Linsley JW, Reisine T, Finkbeiner S. Cell death assays for neurodegenerative disease drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 31179783 DOI: 10.1080/17460441.2019.1623784 |
0.397 |
|
| 2019 |
Finkbeiner S. The Autophagy Lysosomal Pathway and Neurodegeneration. Cold Spring Harbor Perspectives in Biology. PMID 30936119 DOI: 10.1101/Cshperspect.A033993 |
0.346 |
|
| 2019 |
Kedaigle AJ, Fraenkel E, Atwal RS, Wu M, Gusella JF, MacDonald ME, Kaye JA, Finkbeiner S, Mattis VB, Tom CM, Svendsen C, King AR, Chen Y, Stocksdale JT, Lim RG, et al. Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites. Human Molecular Genetics. PMID 30768179 DOI: 10.1093/Hmg/Ddy430 |
0.402 |
|
| 2019 |
Elia LP, Mason AR, Alijagic A, Finkbeiner S. Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30696728 DOI: 10.1523/Jneurosci.3498-17.2019 |
0.466 |
|
| 2018 |
Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Wong JS, Daub AC, Giorgini F, Finkbeiner S. Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nature Communications. 9: 3191. PMID 30266909 DOI: 10.1038/S41467-018-05653-Z |
0.47 |
|
| 2018 |
Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Finkbeiner S, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027 |
0.318 |
|
| 2018 |
Epstein I, Finkbeiner S. The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease. Seminars in Cell & Developmental Biology. 77: 63-72. PMID 29559111 DOI: 10.1016/J.Semcdb.2017.09.023 |
0.388 |
|
| 2017 |
Ramdzan YM, Trubetskov MM, Ormsby AR, Newcombe EA, Sui X, Tobin MJ, Bongiovanni MN, Gras SL, Dewson G, Miller JML, Finkbeiner S, Moily NS, Niclis J, Parish CL, Purcell AW, et al. Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis. Cell Reports. 19: 919-927. PMID 28467905 DOI: 10.1016/J.Celrep.2017.04.029 |
0.332 |
|
| 2017 |
Mason AR, Elia LP, Finkbeiner S. The Receptor-Interacting Serine/Threonine Protein Kinase 1 (Ripk1) Regulates Progranulin Levels. The Journal of Biological Chemistry. PMID 28069809 DOI: 10.1074/Jbc.M116.752006 |
0.429 |
|
| 2016 |
Mao Y, Chen X, Xu M, Fujita K, Motoki K, Sasabe T, Homma H, Murata M, Tagawa K, Tamura T, Kaye J, Finkbeiner S, Blandino G, Sudol M, Okazawa H. Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology. Human Molecular Genetics. 25: 4749-4770. PMID 28171658 DOI: 10.1093/Hmg/Ddw303 |
0.424 |
|
| 2016 |
Skibinski G, Hwang V, Ando DM, Daub A, Lee AK, Ravisankar A, Modan S, Finucane MM, Shaby BA, Finkbeiner S. Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28028237 DOI: 10.1073/Pnas.1522872114 |
0.351 |
|
| 2016 |
Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, ... ... Finkbeiner S, et al. Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. Neuron. PMID 27773581 DOI: 10.1016/J.Neuron.2016.09.050 |
0.314 |
|
| 2016 |
Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, ... ... Finkbeiner S, et al. Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Scientific Reports. 6: 33861. PMID 27653664 DOI: 10.1038/Srep33861 |
0.376 |
|
| 2016 |
Mao Y, Chen X, Xu M, Fujita K, Motoki K, Sasabe T, Homma H, Murata M, Tagawa K, Tamura T, Kaye J, Finkbeiner S, Blandino G, Sudol M, Okazawa H. Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology. Human Molecular Genetics. PMID 27619483 DOI: 10.1093/hmg/ddw303 |
0.317 |
|
| 2016 |
Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/Jci80339 |
0.742 |
|
| 2016 |
Moruno Manchon JF, Uzor NE, Finkbeiner S, Tsvetkov AS. SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. Autophagy. 12: 1418-24. PMID 27467777 DOI: 10.1080/15548627.2016.1183082 |
0.399 |
|
| 2016 |
Oliveira AO, Osmand A, Outeiro TF, Muchowski PJ, Finkbeiner S. αB-Crystallin over-expression in astrocytes modulates the phenotype of the BACHD mouse model of Huntington's disease. Human Molecular Genetics. PMID 26920069 DOI: 10.1093/Hmg/Ddw028 |
0.439 |
|
| 2016 |
Shaby BA, Skibinski G, Ando M, LaDow ES, Finkbeiner S. A three-groups model for high-throughput survival screens. Biometrics. PMID 26821783 DOI: 10.1111/Biom.12479 |
0.369 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Finkbeiner S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.314 |
|
| 2016 |
Haston KM, Finkbeiner S. Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases. Annual Review of Pharmacology and Toxicology. 56: 489-510. PMID 26514199 DOI: 10.1146/Annurev-Pharmtox-010715-103548 |
0.331 |
|
| 2015 |
Moruno Manchon JF, Uzor NE, Dabaghian Y, Furr-Stimming EE, Finkbeiner S, Tsvetkov AS. Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. Scientific Reports. 5: 15213. PMID 26477494 DOI: 10.1038/Srep15213 |
0.433 |
|
| 2015 |
Lee JM, Kim KH, Shin A, Chao MJ, Abu Elneel K, Gillis T, Mysore JS, Kaye JA, Zahed H, Kratter IH, Daub AC, Finkbeiner S, Li H, Roach JC, Goodman N, et al. Sequence-Level Analysis of the Major European Huntington Disease Haplotype. American Journal of Human Genetics. 97: 435-44. PMID 26320893 DOI: 10.1016/J.Ajhg.2015.07.017 |
0.715 |
|
| 2015 |
Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EM, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-6. PMID 26056265 DOI: 10.1073/Pnas.1509744112 |
0.405 |
|
| 2015 |
Campioni MR, Finkbeiner S. Going retro: ancient viral origins of cognition. Neuron. 86: 346-8. PMID 25905805 DOI: 10.1016/J.Neuron.2015.04.008 |
0.341 |
|
| 2014 |
Vieira FG, LaDow E, Moreno A, Kidd JD, Levine B, Thompson K, Gill A, Finkbeiner S, Perrin S. Dexpramipexole is ineffective in two models of ALS related neurodegeneration. Plos One. 9: e91608. PMID 25526593 DOI: 10.1371/Journal.Pone.0091608 |
0.385 |
|
| 2014 |
Ochaba J, Lukacsovich T, Csikos G, Zheng S, Margulis J, Salazar L, Mao K, Lau AL, Yeung SY, Humbert S, Saudou F, Klionsky DJ, Finkbeiner S, Zeitlin SO, Marsh JL, et al. Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: 16889-94. PMID 25385587 DOI: 10.1073/Pnas.1420103111 |
0.379 |
|
| 2014 |
Mason AR, Ziemann A, Finkbeiner S. Targeting the low-hanging fruit of neurodegeneration. Neurology. 83: 1470-3. PMID 25313376 DOI: 10.1212/Wnl.0000000000000894 |
0.301 |
|
| 2014 |
Margulis J, Finkbeiner S. Proteostasis in striatal cells and selective neurodegeneration in Huntington's disease. Frontiers in Cellular Neuroscience. 8: 218. PMID 25147502 DOI: 10.3389/Fncel.2014.00218 |
0.478 |
|
| 2014 |
Barmada SJ, Serio A, Arjun A, Bilican B, Daub A, Ando DM, Tsvetkov A, Pleiss M, Li X, Peisach D, Shaw C, Chandran S, Finkbeiner S. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models. Nature Chemical Biology. 10: 677-85. PMID 24974230 DOI: 10.1038/Nchembio.1563 |
0.432 |
|
| 2014 |
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, et al. Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. Plos One. 9: e87133. PMID 24551051 DOI: 10.1371/Journal.Pone.0087133 |
0.382 |
|
| 2014 |
Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 124: 981-99. PMID 24509083 DOI: 10.1172/Jci72723 |
0.38 |
|
| 2014 |
Skibinski G, Nakamura K, Cookson MR, Finkbeiner S. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 418-33. PMID 24403142 DOI: 10.1523/Jneurosci.2712-13.2014 |
0.406 |
|
| 2014 |
You SC, Geschwind MD, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess CP, Kramer JH, Possin KL. Executive functions in premanifest Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 405-9. PMID 24375511 DOI: 10.1002/Mds.25762 |
0.322 |
|
| 2014 |
Kim HJ, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM, Finkbeiner S, Gitler AD, Bonini NM. Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Nature Genetics. 46: 152-60. PMID 24336168 DOI: 10.1038/Ng.2853 |
0.396 |
|
| 2014 |
Alexander S, Mason A, Finkbeiner S. LONGITUDINAL IMAGING AND ANALYSIS OF TAU-EXPRESSING NEURONS Journal of Neurology, Neurosurgery & Psychiatry. 85: e4.166-e4. DOI: 10.1136/Jnnp-2014-309236.54 |
0.378 |
|
| 2013 |
Korb E, Finkbeiner S. PML in the Brain: From Development to Degeneration. Frontiers in Oncology. 3: 242. PMID 24062991 DOI: 10.3389/Fonc.2013.00242 |
0.329 |
|
| 2013 |
Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2: e00508. PMID 24040509 DOI: 10.7554/Elife.00508 |
0.325 |
|
| 2013 |
Tsvetkov AS, Arrasate M, Barmada S, Ando DM, Sharma P, Shaby BA, Finkbeiner S. Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration. Nature Chemical Biology. 9: 586-92. PMID 23873212 DOI: 10.1038/Nchembio.1308 |
0.446 |
|
| 2013 |
Vashishtha M, Ng CW, Yildirim F, Gipson TA, Kratter IH, Bodai L, Song W, Lau A, Labadorf A, Vogel-Ciernia A, Troncosco J, Ross CA, Bates GP, Krainc D, Sadri-Vakili G, ... Finkbeiner S, et al. Targeting H3K4 trimethylation in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E3027-36. PMID 23872847 DOI: 10.1073/Pnas.1311323110 |
0.758 |
|
| 2013 |
Korb E, Wilkinson CL, Delgado RN, Lovero KL, Finkbeiner S. Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity. Nature Neuroscience. 16: 874-83. PMID 23749147 DOI: 10.1038/Nn.3429 |
0.364 |
|
| 2013 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Finkbeiner S, et al. Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2. PMID 23740897 DOI: 10.1126/Scitranslmed.3005065 |
0.302 |
|
| 2013 |
Tsvetkov AS, Ando DM, Finkbeiner S. Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins. Methods in Molecular Biology (Clifton, N.J.). 1017: 1-20. PMID 23719904 DOI: 10.1007/978-1-62703-438-8_1 |
0.434 |
|
| 2013 |
Aron R, Tsvetkov A, Finkbeiner S. NUB1 snubs huntingtin toxicity. Nature Neuroscience. 16: 523-5. PMID 23619755 DOI: 10.1038/Nn.3380 |
0.391 |
|
| 2013 |
Kaye JA, Finkbeiner S. Modeling Huntington's disease with induced pluripotent stem cells. Molecular and Cellular Neurosciences. 56: 50-64. PMID 23459227 DOI: 10.1016/J.Mcn.2013.02.005 |
0.385 |
|
| 2013 |
Skibinski G, Finkbeiner S. Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease. Febs Letters. 587: 1139-46. PMID 23458259 DOI: 10.1016/J.Febslet.2013.02.043 |
0.42 |
|
| 2013 |
Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, ... ... Finkbeiner S, et al. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 110: 4697-702. PMID 23401527 DOI: 10.1073/Pnas.1300398110 |
0.392 |
|
| 2012 |
Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/Ng.2434 |
0.435 |
|
| 2012 |
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113 |
0.389 |
|
| 2012 |
Wray S, Self M, Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, ... ... Finkbeiner S, et al. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. Plos One. 7: e43099. PMID 22952635 DOI: 10.1371/Journal.Pone.0043099 |
0.323 |
|
| 2012 |
Sontag EM, Lotz GP, Agrawal N, Tran A, Aron R, Yang G, Necula M, Lau A, Finkbeiner S, Glabe C, Marsh JL, Muchowski PJ, Thompson LM. Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11109-19. PMID 22875942 DOI: 10.1523/JNEUROSCI.0895-12.2012 |
0.313 |
|
| 2012 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Finkbeiner S, et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8. PMID 22451909 DOI: 10.1073/Pnas.1202922109 |
0.45 |
|
| 2012 |
Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein. The Journal of Biological Chemistry. 287: 16017-28. PMID 22433867 DOI: 10.1074/Jbc.M111.252577 |
0.391 |
|
| 2012 |
Sharma P, Ando DM, Daub A, Kaye JA, Finkbeiner S. High-throughput screening in primary neurons. Methods in Enzymology. 506: 331-60. PMID 22341232 DOI: 10.1016/B978-0-12-391856-7.00041-X |
0.369 |
|
| 2012 |
Peters-Libeu C, Miller J, Rutenber E, Newhouse Y, Krishnan P, Cheung K, Hatters D, Brooks E, Widjaja K, Tran T, Mitra S, Arrasate M, Mosquera LA, Taylor D, Weisgraber KH, ... Finkbeiner S, et al. Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. Journal of Molecular Biology. 421: 587-600. PMID 22306738 DOI: 10.1016/J.Jmb.2012.01.034 |
0.342 |
|
| 2012 |
Arrasate M, Finkbeiner S. Protein aggregates in Huntington's disease. Experimental Neurology. 238: 1-11. PMID 22200539 DOI: 10.1016/J.Expneurol.2011.12.013 |
0.463 |
|
| 2012 |
Mattis V, Svendsen S, Ebert A, Svendsen C, King A, Casale M, Winokur S, Batugedara G, Vawter M, Donovan P, Lock L, Thompson L, Zhu Y, Fossale E, Atwal R, ... ... Finkbeiner S, et al. A11 Induced pluripotent stem cells for basic and translational research on HD Journal of Neurology, Neurosurgery & Psychiatry. 83: A3.2-A4. DOI: 10.1136/Jnnp-2012-303524.11 |
0.428 |
|
| 2012 |
Mattis VB, Svendsen SP, Ebert A, Svendsen CN, King AR, Casale M, Winokur ST, Batugedara G, Vawter M, Donovan PJ, Lock LF, Thompson LM, Zhu Y, Fossale E, Atwal RS, ... ... Finkbeiner S, et al. Induced pluripotent stem cells from patients with huntington’s disease show CAG repeat expansion associated phenotypes Cell Stem Cell. 11: 264-278. DOI: 10.1016/J.Stem.2012.04.027 |
0.374 |
|
| 2011 |
Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Finkbeiner S, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/Nchembio.694 |
0.349 |
|
| 2011 |
Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, et al. A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 7: 1273-94. PMID 21997368 DOI: 10.4161/Auto.7.11.17661 |
0.304 |
|
| 2011 |
Korb E, Finkbeiner S. Arc in synaptic plasticity: from gene to behavior. Trends in Neurosciences. 34: 591-8. PMID 21963089 DOI: 10.1016/J.Tins.2011.08.007 |
0.438 |
|
| 2011 |
Gittis AH, Hang GB, LaDow ES, Shoenfeld LR, Atallah BV, Finkbeiner S, Kreitzer AC. Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. Neuron. 71: 858-68. PMID 21903079 DOI: 10.1016/J.Neuron.2011.06.035 |
0.355 |
|
| 2011 |
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, et al. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. The Journal of Biological Chemistry. 286: 20710-26. PMID 21489994 DOI: 10.1074/Jbc.M110.213538 |
0.342 |
|
| 2011 |
Finkbeiner S. Huntington's Disease. Cold Spring Harbor Perspectives in Biology. 3. PMID 21441583 DOI: 10.1101/Cshperspect.A007476 |
0.388 |
|
| 2011 |
Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. A compact beta model of huntingtin toxicity. The Journal of Biological Chemistry. 286: 8188-96. PMID 21209075 DOI: 10.1074/Jbc.M110.192013 |
0.35 |
|
| 2010 |
Barmada SJ, Finkbeiner S. Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways. Reviews in the Neurosciences. 21: 251-72. PMID 21086759 DOI: 10.1515/Revneuro.2010.21.4.251 |
0.403 |
|
| 2010 |
Finkbeiner S. Bridging the Valley of Death of therapeutics for neurodegeneration. Nature Medicine. 16: 1227-32. PMID 21052079 DOI: 10.1038/Nm.2222 |
0.308 |
|
| 2010 |
Peebles CL, Yoo J, Thwin MT, Palop JJ, Noebels JL, Finkbeiner S. Arc regulates spine morphology and maintains network stability in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 18173-8. PMID 20921410 DOI: 10.1073/Pnas.1006546107 |
0.333 |
|
| 2010 |
Kratter IH, Finkbeiner S. PolyQ disease: too many Qs, too much function? Neuron. 67: 897-9. PMID 20869586 DOI: 10.1016/J.Neuron.2010.09.012 |
0.727 |
|
| 2010 |
Tsvetkov AS, Miller J, Arrasate M, Wong JS, Pleiss MA, Finkbeiner S. A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model. Proceedings of the National Academy of Sciences of the United States of America. 107: 16982-7. PMID 20833817 DOI: 10.1073/Pnas.1004498107 |
0.457 |
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| 2010 |
Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10541-50. PMID 20685997 DOI: 10.1523/Jneurosci.0146-10.2010 |
0.431 |
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| 2010 |
Ramdzan YM, Nisbet RM, Miller J, Finkbeiner S, Hill AF, Hatters DM. Conformation sensors that distinguish monomeric proteins from oligomers in live cells. Chemistry & Biology. 17: 371-9. PMID 20416508 DOI: 10.1016/J.Chembiol.2010.03.011 |
0.328 |
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| 2010 |
Landles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP. Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. The Journal of Biological Chemistry. 285: 8808-23. PMID 20086007 DOI: 10.1074/Jbc.M109.075028 |
0.304 |
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| 2010 |
Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S. Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 639-49. PMID 20071528 DOI: 10.1523/Jneurosci.4988-09.2010 |
0.428 |
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| 2010 |
Tsvetkov AS, Finkbeiner S. Reply to Rubinsztein and Nixon: Potent and reliable autophagy induction in neurons Proceedings of the National Academy of Sciences of the United States of America. 107: E182. DOI: 10.1073/Pnas.1014950107 |
0.353 |
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| 2009 |
Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron. 64: 828-40. PMID 20064390 DOI: 10.1016/J.Neuron.2009.11.020 |
0.39 |
|
| 2009 |
Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, ... ... Finkbeiner S, et al. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of Cell Biology. 187: 1083-99. PMID 20026656 DOI: 10.1083/Jcb.200909067 |
0.428 |
|
| 2009 |
Mitra S, Tsvetkov AS, Finkbeiner S. Protein turnover and inclusion body formation. Autophagy. 5: 1037-8. PMID 19838079 DOI: 10.4161/Auto.5.7.9291 |
0.452 |
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| 2009 |
Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE. Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. Human Molecular Genetics. 18: 1937-50. PMID 19279159 DOI: 10.1093/Hmg/Ddp115 |
0.409 |
|
| 2009 |
Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1525-37. PMID 19193899 DOI: 10.1523/Jneurosci.5575-08.2009 |
0.738 |
|
| 2009 |
Mitra S, Tsvetkov AS, Finkbeiner S. Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease. The Journal of Biological Chemistry. 284: 4398-403. PMID 19074152 DOI: 10.1074/Jbc.M806269200 |
0.456 |
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| 2008 |
Finkbeiner S, Mitra S. The ubiquitin-proteasome pathway in Huntington's disease. Thescientificworldjournal. 8: 421-33. PMID 18454252 DOI: 10.1100/Tsw.2008.60 |
0.44 |
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| 2007 |
Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/J.Neuron.2007.07.025 |
0.413 |
|
| 2007 |
Peebles CL, Finkbeiner S. RNA decay back in play. Nature Neuroscience. 10: 1083-4. PMID 17726472 DOI: 10.1038/Nn0907-1083 |
0.334 |
|
| 2007 |
Rao VR, Finkbeiner S. NMDA and AMPA receptors: old channels, new tricks. Trends in Neurosciences. 30: 284-91. PMID 17418904 DOI: 10.1016/J.Tins.2007.03.012 |
0.341 |
|
| 2006 |
Beal MF, Bossy-Wetzel E, Finkbeiner S, Fiskum G, Giasson B, Johnson C, Khachaturian ZS, Lee VM, Nicholls D, Reddy H, Reynolds I, Teplow DB, Thal LJ, Trojanowski JQ, Walsh DM, et al. Common threads in neurodegenerative disorders of aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 322-6. PMID 19595906 DOI: 10.1016/J.Jalz.2006.08.008 |
0.349 |
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| 2006 |
Finkbeiner S, Cuervo AM, Morimoto RI, Muchowski PJ. Disease-modifying pathways in neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10349-57. PMID 17035516 DOI: 10.1523/Jneurosci.3829-06.2006 |
0.397 |
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| 2006 |
Rao VR, Pintchovski SA, Chin J, Peebles CL, Mitra S, Finkbeiner S. AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc. Nature Neuroscience. 9: 887-95. PMID 16732277 DOI: 10.1038/Nn1708 |
0.744 |
|
| 2006 |
Bradley J, Carter SR, Rao VR, Wang J, Finkbeiner S. Splice variants of the NR1 subunit differentially induce NMDA receptor-dependent gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1065-76. PMID 16436592 DOI: 10.1523/Jneurosci.3347-05.2006 |
0.382 |
|
| 2005 |
Arrasate M, Finkbeiner S. Automated microscope system for determining factors that predict neuronal fate. Proceedings of the National Academy of Sciences of the United States of America. 102: 3840-5. PMID 15738408 DOI: 10.1073/Pnas.0409777102 |
0.328 |
|
| 2004 |
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature. 431: 805-10. PMID 15483602 DOI: 10.1038/Nature02998 |
0.401 |
|
| 2003 |
Rao VR, Finkbeiner S. Secrets of a secretase: N-cadherin proteolysis regulates CBP function. Cell. 114: 533-5. PMID 13678577 DOI: 10.1016/S0092-8674(03)00686-X |
0.356 |
|
| 2002 |
Bradley J, Finkbeiner S. An evaluation of specificity in activity-dependent gene expression in neurons. Progress in Neurobiology. 67: 469-77. PMID 12385865 DOI: 10.1016/S0301-0082(02)00047-3 |
0.369 |
|
| 2002 |
Humbert S, Bryson EA, Cordelières FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME, Saudou F. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Developmental Cell. 2: 831-7. PMID 12062094 DOI: 10.1016/S1534-5807(02)00188-0 |
0.368 |
|
| 2001 |
Finkbeiner S. New roles for introns: sites of combinatorial regulation of Ca2+- and cyclic AMP-dependent gene transcription Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001: PE1. PMID 11752669 DOI: 10.1126/Stke.2001.94.Pe1 |
0.348 |
|
| 2000 |
Finkbeiner S. Calcium regulation of the brain-derived neurotrophic factor gene Cellular and Molecular Life Sciences. 57: 394-401. PMID 10823240 DOI: 10.1007/Pl00000701 |
0.357 |
|
| 2000 |
Finkbeiner S. CREB couples neurotrophin signals to survival messages Neuron. 25: 11-14. PMID 10707967 DOI: 10.1016/S0896-6273(00)80866-1 |
0.407 |
|
| 1999 |
Curtis J, Finkbeiner S. Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth Journal of Neuroscience Research. 58: 88-95. PMID 10491574 DOI: 10.1002/(Sici)1097-4547(19991001)58:1<88::Aid-Jnr9>3.0.Co;2-R |
0.385 |
|
| 1998 |
Finkbeiner S, Dalva MB. To fear or not to fear: what was the question? A potential role for Ras-GRF in memory. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 691-5. PMID 9819557 DOI: 10.1002/(Sici)1521-1878(199809)20:9<691::Aid-Bies1>3.0.Co;2-K |
0.365 |
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| 1998 |
Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95: 55-66. PMID 9778247 DOI: 10.1016/S0092-8674(00)81782-1 |
0.396 |
|
| 1998 |
Finkbeiner S, Greenberg ME. Ca2+ channel-regulated neuronal gene expression. Journal of Neurobiology. 37: 171-89. PMID 9777740 DOI: 10.1002/(Sici)1097-4695(199810)37:1<171::Aid-Neu13>3.0.Co;2-H |
0.401 |
|
| 1998 |
Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron. 20: 709-26. PMID 9581763 DOI: 10.1016/S0896-6273(00)81010-7 |
0.422 |
|
| 1997 |
Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME. CREB: a major mediator of neuronal neurotrophin responses. Neuron. 19: 1031-47. PMID 9390517 DOI: 10.1016/S0896-6273(00)80395-5 |
0.44 |
|
| 1997 |
Finkbeiner S, Greenberg ME. Spatial features of calcium-regulated gene expression. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 657-60. PMID 9264245 DOI: 10.1002/Bies.950190803 |
0.386 |
|
| 1996 |
Finkbeiner S, Greenberg ME. Ca(2+)-dependent routes to Ras: mechanisms for neuronal survival, differentiation, and plasticity? Neuron. 16: 233-6. PMID 8789937 DOI: 10.1016/S0896-6273(00)80040-9 |
0.308 |
|
| 1996 |
Finkbeiner S. Neurotrophins and the synapse Neuroscientist. 2: 139-142. |
0.305 |
|
| 1992 |
van den Pol AN, Finkbeiner SM, Cornell-Bell AH. Calcium excitability and oscillations in suprachiasmatic nucleus neurons and glia in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2648-64. PMID 1351936 DOI: 10.1523/Jneurosci.12-07-02648.1992 |
0.308 |
|
| 1988 |
Finkbeiner S, Stevens CF. Applications of quantitative measurements for assessing glutamate neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 85: 4071-4. PMID 2453886 DOI: 10.1073/Pnas.85.11.4071 |
0.316 |
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