| Year |
Citation |
Score |
| 2024 |
Liao SC, Kano K, Phanse S, Nguyen M, Margolis E, Fu Y, Meng J, Moutaoufik MT, Chatterton Z, Aoki H, Simms J, Hsieh I, Suteja F, Sei Y, Huang EJ, ... ... Nakamura K, et al. CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism. Biorxiv : the Preprint Server For Biology. PMID 39257750 DOI: 10.1101/2024.08.30.610586 |
0.313 |
|
| 2024 |
Rademacher K, Doric Z, Haddad D, Mamaligas A, Liao SC, Creed RB, Kano K, Chatterton Z, Fu Y, Garcia JH, Vance V, Sei Y, Kreitzer A, Halliday GM, Nelson AB, ... ... Nakamura K, et al. Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration. Biorxiv : the Preprint Server For Biology. PMID 38645054 DOI: 10.1101/2024.04.05.588321 |
0.302 |
|
| 2023 |
Rademacher K, Nakamura K. Role of dopamine neuron activity in Parkinson's disease pathophysiology. Experimental Neurology. 114645. PMID 38092187 DOI: 10.1016/j.expneurol.2023.114645 |
0.329 |
|
| 2021 |
Doric Z, Li H, Nakamura K. The PINK1 advantage: recycling mitochondria in times of trouble? Autophagy. 18: 231-232. PMID 34812108 DOI: 10.1080/15548627.2021.1998872 |
0.321 |
|
| 2021 |
Nguyen MK, McAvoy K, Liao SC, Doric Z, Lo I, Li H, Manfredi G, Nakamura K. Mouse midbrain dopaminergic neurons survive loss of the PD-associated mitochondrial protein CHCHD2. Human Molecular Genetics. PMID 34791217 DOI: 10.1093/hmg/ddab329 |
0.331 |
|
| 2021 |
Li H, Doric Z, Berthet A, Jorgens DM, Nguyen MK, Hsieh I, Margulis J, Fang R, Debnath J, Sesaki H, Finkbeiner S, Huang E, Nakamura K. Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation. Science Advances. 7. PMID 34362731 DOI: 10.1126/sciadv.abf6580 |
0.316 |
|
| 2019 |
Zhang J, Shang Y, Kamiya S, Kotowski SJ, Nakamura K, Huang EJ. Loss of HIPK2 protects neurons from mitochondrial toxins by regulating Parkin protein turnover. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31776210 DOI: 10.1523/Jneurosci.2017-19.2019 |
0.394 |
|
| 2018 |
Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K. A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. Plos Biology. 16: e2004624. PMID 30148842 DOI: 10.1371/Journal.Pbio.2004624 |
0.326 |
|
| 2017 |
Pathak D, Berthet A, Bendor JT, Yu K, Sellnow RC, Orr AL, Nguyen MK, Edwards RH, Manfredsson FP, Nakamura K. Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons. Eneuro. 4. PMID 28462393 DOI: 10.1523/ENEURO.0216-16.2017 |
0.338 |
|
| 2017 |
Orr AL, Rutaganira FU, de Roulet D, Huang EJ, Hertz NT, Shokat KM, Nakamura K. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochemistry International. PMID 28434973 DOI: 10.1016/J.Neuint.2017.04.006 |
0.41 |
|
| 2017 |
Haddad D, Nakamura K. PINK1-Based Screen Shines Light on Autophagy Enhancers for Parkinson's Disease. Cell Chemical Biology. 24: 429-430. PMID 28431223 DOI: 10.1016/J.Chembiol.2017.04.002 |
0.346 |
|
| 2015 |
Haddad D, Nakamura K. Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease. Febs Letters. PMID 26526613 DOI: 10.1016/J.Febslet.2015.10.021 |
0.428 |
|
| 2015 |
Pathak D, Shields L, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling. The Journal of Biological Chemistry. PMID 26126824 DOI: 10.1074/Jbc.M115.656405 |
0.337 |
|
| 2015 |
Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez LG, Gill TM, Sesaki H, Mucke L, Nakamura K. Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. Cell Death & Disease. 6: e1725. PMID 25880092 DOI: 10.1038/Cddis.2015.94 |
0.391 |
|
| 2014 |
Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14304-17. PMID 25339743 DOI: 10.1523/Jneurosci.0930-14.2014 |
0.409 |
|
| 2014 |
Skibinski G, Nakamura K, Cookson MR, Finkbeiner S. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 418-33. PMID 24403142 DOI: 10.1523/Jneurosci.2712-13.2014 |
0.402 |
|
| 2013 |
Pathak D, Berthet A, Nakamura K. Energy failure: does it contribute to neurodegeneration? Annals of Neurology. 74: 506-16. PMID 24038413 DOI: 10.1002/Ana.24014 |
0.338 |
|
| 2013 |
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 501: 512-6. PMID 24005326 DOI: 10.1038/Nature12566 |
0.305 |
|
| 2013 |
Hertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 154: 737-47. PMID 23953109 DOI: 10.1016/J.Cell.2013.07.030 |
0.391 |
|
| 2013 |
Yoshida S, Tsutsumi S, Muhlebach G, Sourbier C, Lee MJ, Lee S, Vartholomaiou E, Tatokoro M, Beebe K, Miyajima N, Mohney RP, Chen Y, Hasumi H, Xu W, Fukushima H, ... Nakamura K, et al. Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1604-12. PMID 23564345 DOI: 10.1073/Pnas.1220659110 |
0.309 |
|
| 2013 |
Itoh K, Nakamura K, Iijima M, Sesaki H. Mitochondrial dynamics in neurodegeneration. Trends in Cell Biology. 23: 64-71. PMID 23159640 DOI: 10.1016/J.Tcb.2012.10.006 |
0.364 |
|
| 2011 |
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, et al. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. The Journal of Biological Chemistry. 286: 20710-26. PMID 21489994 DOI: 10.1074/Jbc.M110.213538 |
0.405 |
|
| 2010 |
Fortin DL, Nemani VM, Nakamura K, Edwards RH. The behavior of alpha-synuclein in neurons. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S21-6. PMID 20187244 DOI: 10.1002/Mds.22722 |
0.306 |
|
| 2010 |
Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 65: 66-79. PMID 20152114 DOI: 10.1016/J.Neuron.2009.12.023 |
0.314 |
|
| 2008 |
Nakamura K, Nemani VM, Wallender EK, Kaehlcke K, Ott M, Edwards RH. Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12305-17. PMID 19020024 DOI: 10.1523/Jneurosci.3088-08.2008 |
0.353 |
|
| 2007 |
Nakamura K, Edwards RH. Physiology versus pathology in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 11867-8. PMID 17623781 DOI: 10.1073/Pnas.0704254104 |
0.383 |
|
| 2007 |
Nakamura K, Aminoff MJ. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs of Today (Barcelona, Spain : 1998). 43: 97-116. PMID 17353947 DOI: 10.1358/Dot.2007.43.2.1050788 |
0.302 |
|
| 2004 |
Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. Lipid rafts mediate the synaptic localization of alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6715-23. PMID 15282274 DOI: 10.1523/Jneurosci.1594-04.2004 |
0.319 |
|
| 2001 |
Nakamura K, Bindokas VP, Kowlessur D, Elas M, Milstien S, Marks JD, Halpern HJ, Kang UJ. Tetrahydrobiopterin Scavenges Superoxide in Dopaminergic Neurons Journal of Biological Chemistry. 276: 34402-34407. PMID 11447224 DOI: 10.1074/Jbc.M103766200 |
0.368 |
|
| 2000 |
Nakamura K, Ahmed M, Barr E, Leiden JM, Kang UJ. The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3,4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models. Cell Transplantation. 9: 567-76. PMID 11144954 DOI: 10.1177/096368970000900502 |
0.33 |
|
| 2000 |
Nakamura K, Won L, Heller A, Kang UJ. Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system. Brain Research. 873: 203-11. PMID 10930545 DOI: 10.1016/S0006-8993(00)02425-2 |
0.39 |
|
| 2000 |
Nakamura K, Bindokas VP, Marks JD, Wright DA, Frim DM, Miller RJ, Kang UJ. The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited. Molecular Pharmacology. 58: 271-8. PMID 10908294 DOI: 10.1124/Mol.58.2.271 |
0.43 |
|
| 2000 |
Nakamura K, Wright DA, Wiatr T, Kowlessur D, Milstien S, Lei XG, Kang UJ. Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin. Journal of Neurochemistry. 74: 2305-14. PMID 10820190 DOI: 10.1046/J.1471-4159.2000.0742305.X |
0.391 |
|
| 1997 |
Nakamura K, Wang W, Kang UJ. The role of glutathione in dopaminergic neuronal survival. Journal of Neurochemistry. 69: 1850-8. PMID 9349527 DOI: 10.1046/J.1471-4159.1997.69051850.X |
0.39 |
|
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