Year |
Citation |
Score |
2022 |
Faynus MA, Bailey JK, Pennington BO, Katsura M, Proctor DA, Yeh AK, Menon S, Choi DG, Lebkowski JS, Johnson LV, Clegg DO. Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium. Bioengineering (Basel, Switzerland). 9. PMID 35877348 DOI: 10.3390/bioengineering9070297 |
0.343 |
|
2021 |
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, ... Johnson LV, et al. Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo. Scientific Reports. 11: 6286. PMID 33737600 DOI: 10.1038/s41598-021-85631-6 |
0.338 |
|
2018 |
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, et al. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science Translational Medicine. 10. PMID 29618560 DOI: 10.1126/Scitranslmed.Aao4097 |
0.425 |
|
2017 |
Toomey CB, Johnson LV, Rickman CB. Complement factor H in AMD: Bridging genetic associations and pathobiology. Progress in Retinal and Eye Research. PMID 28928087 DOI: 10.1016/J.Preteyeres.2017.09.001 |
0.395 |
|
2016 |
Lopez P, Aguilar T, Wu R, Krishnan A, Kong D, Patel J, Javier H, Dang W, Wong D, Zhu D, Dodd J, Shad Y, Humayun M, Hinton D, Clegg D, ... Johnson L, et al. 445. cGMP Compliant Production for Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cells on a Synthetic Substrate for the Treatment of Non-Neovascular Age-Related Macular Degeneration for Phase I Clinical Study Molecular Therapy. 24: S176. DOI: 10.1016/S1525-0016(16)33254-3 |
0.484 |
|
2015 |
Radeke MJ, Radeke CM, Shih YH, Hu J, Bok D, Johnson LV, Coffey PJ. Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration. Genome Medicine. 7: 58. PMID 26150894 DOI: 10.1186/S13073-015-0183-X |
0.428 |
|
2015 |
Forest DL, Johnson LV, Clegg DO. Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8: 421-7. PMID 26035859 DOI: 10.1242/Dmm.017236 |
0.451 |
|
2013 |
Gorham RD, Forest DL, Tamamis P, López de Victoria A, Kraszni M, Kieslich CA, Banna CD, Bellows-Peterson ML, Larive CK, Floudas CA, Archontis G, Johnson LV, Morikis D. Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures. Experimental Eye Research. 116: 96-108. PMID 23954241 DOI: 10.1016/J.Exer.2013.07.023 |
0.383 |
|
2013 |
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7: 642-53. PMID 22514096 DOI: 10.1002/Term.1458 |
0.446 |
|
2012 |
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS. A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48: 186-91. PMID 22868580 DOI: 10.1159/000338749 |
0.354 |
|
2012 |
Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, Cooper JB, Hageman GS, Anderson DH, Johnson LV, Radeke MJ. Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Medicine. 4: 16. PMID 22364233 DOI: 10.1186/Gm315 |
0.481 |
|
2011 |
Johnson LV, Forest DL, Banna CD, Radeke CM, Maloney MA, Hu J, Spencer CN, Walker AM, Tsie MS, Bok D, Radeke MJ, Anderson DH. Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 108: 18277-82. PMID 21969589 DOI: 10.1073/Pnas.1109703108 |
0.432 |
|
2011 |
Ding JD, Johnson LV, Herrmann R, Farsiu S, Smith SG, Groelle M, Mace BE, Sullivan P, Jamison JA, Kelly U, Harrabi O, Bollini SS, Dilley J, Kobayashi D, Kuang B, et al. Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 108: E279-87. PMID 21690377 DOI: 10.1073/Pnas.1100901108 |
0.389 |
|
2010 |
Hu Q, Friedrich AM, Johnson LV, Clegg DO. Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells (Dayton, Ohio). 28: 1981-91. PMID 20882530 DOI: 10.1002/Stem.531 |
0.381 |
|
2010 |
Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, Curletti CR, Hancox LS, Hu J, Ebright JN, Malek G, Hauser MA, Rickman CB, Bok D, Hageman GS, Johnson LV. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Progress in Retinal and Eye Research. 29: 95-112. PMID 19961953 DOI: 10.1016/J.Preteyeres.2009.11.003 |
0.436 |
|
2010 |
Isas JM, Luibl V, Johnson LV, Kayed R, Wetzel R, Glabe CG, Langen R, Chen J. Soluble and mature amyloid fibrils in drusen deposits. Investigative Ophthalmology & Visual Science. 51: 1304-10. PMID 19892876 DOI: 10.1167/Iovs.09-4207 |
0.346 |
|
2010 |
Rowland TJ, Miller LM, Blaschke AJ, Doss EL, Bonham AJ, Hikita ST, Johnson LV, Clegg DO. Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells and Development. 19: 1231-40. PMID 19811096 DOI: 10.1089/Scd.2009.0328 |
0.349 |
|
2010 |
Buchholz DE, Hikita ST, Radeke MJ, Blashke KE, Johnson LV, Clegg DO. Stem cell derived retinal pigment Epithelium for the treatment of age-related Macular degeneration Journal of Vision. 8: 47-47. DOI: 10.1167/8.17.47 |
0.474 |
|
2009 |
Carr AJ, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, Buchholz DE, Ahmado A, Semo M, Smart MJ, Hasan S, da Cruz L, Johnson LV, Clegg DO, Coffey PJ. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. Plos One. 4: e8152. PMID 19997644 DOI: 10.1371/Journal.Pone.0008152 |
0.482 |
|
2009 |
Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO. Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 27: 2427-34. PMID 19658190 DOI: 10.1002/Stem.189 |
0.466 |
|
2009 |
Kochounian H, Johnson LV, Fong HK. Accumulation of extracellular RGR-d in Bruch's membrane and close association with drusen at intercapillary regions. Experimental Eye Research. 88: 1129-36. PMID 19450444 DOI: 10.1016/J.Exer.2009.01.019 |
0.349 |
|
2007 |
Radeke MJ, Peterson KE, Johnson LV, Anderson DH. Disease susceptibility of the human macula: differential gene transcription in the retinal pigmented epithelium/choroid. Experimental Eye Research. 85: 366-80. PMID 17662275 DOI: 10.1016/J.Exer.2007.05.006 |
0.4 |
|
2006 |
Hageman GS, Hancox LS, Taiber AJ, Gehrs KM, Anderson DH, Johnson LV, Radeke MJ, Kavanagh D, Richards A, Atkinson J, Meri S, Bergeron J, Zernant J, Merriam J, Gold B, et al. Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications. Annals of Medicine. 38: 592-604. PMID 28950782 DOI: 10.1080/07853890601097030 |
0.376 |
|
2006 |
Gehrs KM, Anderson DH, Johnson LV, Hageman GS. Age-related macular degeneration--emerging pathogenetic and therapeutic concepts. Annals of Medicine. 38: 450-71. PMID 17101537 DOI: 10.1080/07853890600946724 |
0.351 |
|
2006 |
Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV. Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proceedings of the National Academy of Sciences of the United States of America. 103: 17456-61. PMID 17079491 DOI: 10.1016/J.Ajo.2007.01.013 |
0.368 |
|
2005 |
Johnson PT, Brown MN, Pulliam BC, Anderson DH, Johnson LV. Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen. Investigative Ophthalmology & Visual Science. 46: 4788-95. PMID 16303980 DOI: 10.1167/Iovs.05-0767 |
0.436 |
|
2005 |
Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C. Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 11900-5. PMID 16079201 DOI: 10.1016/J.Ajo.2006.01.010 |
0.459 |
|
2005 |
Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 7227-32. PMID 15870199 DOI: 10.1073/Pnas.0501536102 |
0.392 |
|
2004 |
Johnson LV, Anderson DH. Age-related macular degeneration and the extracellular matrix. The New England Journal of Medicine. 351: 320-2. PMID 15269309 DOI: 10.1056/Nejmp048131 |
0.409 |
|
2004 |
Anderson DH, Talaga KC, Rivest AJ, Barron E, Hageman GS, Johnson LV. Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Experimental Eye Research. 78: 243-56. PMID 14729357 DOI: 10.1016/J.Exer.2003.10.011 |
0.38 |
|
2003 |
Tombran-Tink J, Lara N, Chappa A, Tink AR, Johnson LV, Staples M. Identification of downstream mechanisms involved in PEDF'S activity in the retina by large scale gene expression profiling. Advances in Experimental Medicine and Biology. 533: 315-26. PMID 15180279 DOI: 10.1007/978-1-4615-0067-4_39 |
0.394 |
|
2003 |
Johnson PT, Lewis GP, Talaga KC, Brown MN, Kappel PJ, Fisher SK, Anderson DH, Johnson LV. Drusen-associated degeneration in the retina. Investigative Ophthalmology & Visual Science. 44: 4481-8. PMID 14507896 DOI: 10.1167/Iovs.03-0436 |
0.486 |
|
2002 |
Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. American Journal of Ophthalmology. 134: 411-31. PMID 12208254 DOI: 10.1016/S0002-9394(02)01624-0 |
0.413 |
|
2002 |
Johnson LV, Leitner WP, Rivest AJ, Staples MK, Radeke MJ, Anderson DH. The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 99: 11830-5. PMID 12189211 DOI: 10.1073/Pnas.192203399 |
0.431 |
|
2002 |
Leu ST, Batni S, Radeke MJ, Johnson LV, Anderson DH, Clegg DO. Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Experimental Eye Research. 74: 141-54. PMID 11878827 DOI: 10.1006/Exer.2001.1112 |
0.38 |
|
2001 |
Johnson LV, Leitner WP, Staples MK, Anderson DH. Complement activation and inflammatory processes in Drusen formation and age related macular degeneration. Experimental Eye Research. 73: 887-96. PMID 11846519 DOI: 10.1006/Exer.2001.1094 |
0.441 |
|
2001 |
Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Progress in Retinal and Eye Research. 20: 705-32. PMID 11587915 DOI: 10.1016/S1350-9462(01)00010-6 |
0.479 |
|
2001 |
Anderson DH, Ozaki S, Nealon M, Neitz J, Mullins RF, Hageman GS, Johnson LV. Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation. American Journal of Ophthalmology. 131: 767-81. PMID 11384575 DOI: 10.1016/S0002-9394(00)00961-2 |
0.457 |
|
2000 |
Johnson LV, Ozaki S, Staples MK, Erickson PA, Anderson DH. A potential role for immune complex pathogenesis in drusen formation. Experimental Eye Research. 70: 441-9. PMID 10865992 DOI: 10.1006/Exer.1999.0798 |
0.429 |
|
1999 |
Anderson DH, Hageman GS, Mullins RF, Neitz M, Neitz J, Ozaki S, Preissner KT, Johnson LV. Vitronectin gene expression in the adult human retina. Investigative Ophthalmology & Visual Science. 40: 3305-15. PMID 10586957 |
0.316 |
|
1999 |
Ozaki S, Johnson LV, Mullins RF, Hageman GS, Anderson DH. The human retina and retinal pigment epithelium are abundant sources of vitronectin mRNA. Biochemical and Biophysical Research Communications. 258: 524-9. PMID 10329419 DOI: 10.1006/Bbrc.1999.0672 |
0.388 |
|
1999 |
Hageman GS, Mullins RF, Russell SR, Johnson LV, Anderson DH. Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 477-84. PMID 10064614 DOI: 10.1096/Fasebj.13.3.477 |
0.505 |
|
1997 |
Mullins RF, Johnson LV, Anderson DH, Hageman GS. Characterization of drusen-associated glycoconjugates. Ophthalmology. 104: 288-94. PMID 9052634 DOI: 10.1016/S0161-6420(97)30322-4 |
0.459 |
|
1996 |
Hageman GS, Mullins RF, Johnson LV, Anderson DH. Cell biology of AMD: Analyses of age-related extracellular deposits Investigative Ophthalmology and Visual Science. 37: S450. |
0.317 |
|
1995 |
Tombran-Tink J, Shivaram SM, Chader GJ, Johnson LV, Bok D. Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4992-5003. PMID 7623128 |
0.365 |
|
1993 |
Blanks JC, Johnson LV, Hageman GS. Stage-specific Binding of Peanut Agglutinin to Aggregates of Degenerating Photoreceptor Cells in the rd Mouse Retina Experimental Eye Research. 57: 265-273. PMID 8224014 DOI: 10.1006/Exer.1993.1124 |
0.309 |
|
1986 |
Blanks JC, Johnson LV. Vascular atrophy in the retinal degenerative rd mouse Journal of Comparative Neurology. 254: 543-553. PMID 3805362 |
0.313 |
|
1986 |
Johnson LV, Hageman GS, Blanks JC. Interphotoreceptor matrix domains ensheath vertebrate cone photoreceptor cells Investigative Ophthalmology and Visual Science. 27: 129-135. PMID 3080382 |
0.322 |
|
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