Kenneth Kosik - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Rani N, Nowakowski TJ, Zhou H, Godshalk SE, Lisi V, Kriegstein AR, Kosik KS. A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA. Neuron. PMID 27263970 DOI: 10.1016/j.neuron.2016.05.005  0.88
2016 Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, ... ... Kosik KS, et al. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 90: 662. PMID 27151643 DOI: 10.1016/j.neuron.2016.04.025  0.88
2016 Jang J, Wang Y, Lalli MA, Guzman E, Godshalk SE, Zhou H, Kosik KS. Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate. Cell. PMID 27020754 DOI: 10.1016/j.cell.2016.02.014  0.88
2016 Kosik KS. Tracking Down Mutations Cell by Cell. Neuron. 89: 1126-7. PMID 26985720 DOI: 10.1016/j.neuron.2016.02.042  0.88
2016 Tang S, Hemberg M, Cansizoglu E, Belin S, Kosik K, Kreiman G, Steen H, Steen J. f-divergence cutoff index to simultaneously identify differential expression in the integrated transcriptome and proteome. Nucleic Acids Research. PMID 26980280 DOI: 10.1093/nar/gkw157  0.88
2016 Conaco C, Tsoulfas P, Sakarya O, Dolan A, Werren J, Kosik KS. Detection of Prokaryotic Genes in the Amphimedon queenslandica Genome. Plos One. 11: e0151092. PMID 26959231 DOI: 10.1371/journal.pone.0151092  0.88
2016 Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA. FLEXITau: Quantifying Post-translational Modifications of Tau Protein in vitro and in Human Disease. Analytical Chemistry. PMID 26877193 DOI: 10.1021/acs.analchem.5b04509  0.88
2016 Lalli MA, Jang J, Park JC, Wang Y, Guzman E, Zhou H, Audouard M, Bridges D, Tovar KR, Papuc SM, Tutulan-Cunita AC, Huang Y, Budisteanu M, Arghir A, Kosik KS. Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. Human Molecular Genetics. PMID 26755828 DOI: 10.1093/hmg/ddw010  0.88
2015 Piedrahita D, Castro-Alvarez JF, Boudreau RL, Villegas-Lanau A, Kosik KS, Gallego-Gomez JC, Cardona-Gómez GP. β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Frontiers in Cellular Neuroscience. 9: 498. PMID 26778963 DOI: 10.3389/fncel.2015.00498  0.88
2015 Corbel C, Hernandez I, Wu B, Kosik KS. Developmental attenuation of N-methyl-D-aspartate receptor subunit expression by microRNAs. Neural Development. 10: 20. PMID 26381867 DOI: 10.1186/s13064-015-0047-5  0.88
2015 Lalli MA, Bettcher BM, Arcila ML, Garcia G, Guzman C, Madrigal L, Ramirez L, Acosta-Uribe J, Baena A, Wojta KJ, Coppola G, Fitch R, de Both MD, Huentelman MJ, Reiman EM, ... ... Kosik KS, et al. Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease. Molecular Psychiatry. PMID 26324103 DOI: 10.1038/mp.2015.131  0.88
2015 Srikanth P, Han K, Callahan DG, Makovkina E, Muratore CR, Lalli MA, Zhou H, Boyd JD, Kosik KS, Selkoe DJ, Young-Pearse TL. Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate. Cell Reports. PMID 26299970 DOI: 10.1016/j.celrep.2015.07.061  0.88
2015 Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, ... ... Kosik KS, et al. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 86: 1215-27. PMID 26004914 DOI: 10.1016/j.neuron.2015.05.005  0.88
2015 Corbel C, Zhang B, Le Parc A, Baratte B, Colas P, Couturier C, Kosik KS, Landrieu I, Le Tilly V, Bach S. Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation. Chemistry & Biology. 22: 472-82. PMID 25865311 DOI: 10.1016/j.chembiol.2015.03.009  0.88
2015 Kosik KS. Personalized medicine for effective Alzheimer disease treatment. Jama Neurology. 72: 497-8. PMID 25730751 DOI: 10.1001/jamaneurol.2014.3445  0.88
2015 Dehay C, Kennedy H, Kosik KS. The outer subventricular zone and primate-specific cortical complexification. Neuron. 85: 683-94. PMID 25695268 DOI: 10.1016/j.neuron.2014.12.060  0.88
2015 Mably AJ, Kanmert D, Mc Donald JM, Liu W, Caldarone BJ, Lemere CA, O'Nuallain B, Kosik KS, Walsh DM. Tau immunization: a cautionary tale? Neurobiology of Aging. 36: 1316-32. PMID 25619661 DOI: 10.1016/j.neurobiolaging.2014.11.022  0.88
2015 Kosik KS, Muñoz C, Lopez L, Arcila ML, García G, Madrigal L, Moreno S, Ríos Romenets S, Lopez H, Gutierrez M, Langbaum JB, Cho W, Suliman S, Tariot PN, Ho C, et al. Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation. Neurology. 84: 206-8. PMID 25471389 DOI: 10.1212/WNL.0000000000001130  0.88
2014 Kenny PJ, Zhou H, Kim M, Skariah G, Khetani RS, Drnevich J, Arcila ML, Kosik KS, Ceman S. MOV10 and FMRP regulate AGO2 association with microRNA recognition elements. Cell Reports. 9: 1729-41. PMID 25464849 DOI: 10.1016/j.celrep.2014.10.054  0.88
2014 Castro-Alvarez JF, Uribe-Arias SA, Kosik KS, Cardona-Gómez GP. Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice. Frontiers in Aging Neuroscience. 6: 243. PMID 25309427 DOI: 10.3389/fnagi.2014.00243  0.88
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Kosik KS, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/nature13716  0.88
2014 Kye MJ, Niederst ED, Wertz MH, Gonçalves Ido C, Akten B, Dover KZ, Peters M, Riessland M, Neveu P, Wirth B, Kosik KS, Sardi SP, Monani UR, Passini MA, Sahin M. SMN regulates axonal local translation via miR-183/mTOR pathway. Human Molecular Genetics. 23: 6318-31. PMID 25055867 DOI: 10.1093/hmg/ddu350  0.88
2014 Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 83: 69-86. PMID 24991955 DOI: 10.1016/j.neuron.2014.05.035  0.88
2014 Lo AW, Ho C, Cummings J, Kosik KS. Parallel discovery of Alzheimer's therapeutics. Science Translational Medicine. 6: 241cm5. PMID 24944190 DOI: 10.1126/scitranslmed.3008228  0.88
2014 Jang J, Wang Y, Kim HS, Lalli MA, Kosik KS. Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. Stem Cells (Dayton, Ohio). 32: 2616-25. PMID 24895273 DOI: 10.1002/stem.1764  0.88
2014 Wang J, Gong Q, Maheshwari N, Eisenstein M, Arcila ML, Kosik KS, Soh HT. Particle display: a quantitative screening method for generating high-affinity aptamers. Angewandte Chemie (International Ed. in English). 53: 4796-801. PMID 24644057 DOI: 10.1002/anie.201309334  0.88
2014 Arcila ML, Betizeau M, Cambronne XA, Guzman E, Doerflinger N, Bouhallier F, Zhou H, Wu B, Rani N, Bassett DS, Borello U, Huissoud C, Goodman RH, Dehay C, Kosik KS. Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns. Neuron. 81: 1255-62. PMID 24583023 DOI: 10.1016/j.neuron.2014.01.017  0.88
2014 Lalli MA, Cox HC, Arcila ML, Cadavid L, Moreno S, Garcia G, Madrigal L, Reiman EM, Arcos-Burgos M, Bedoya G, Brunkow ME, Glusman G, Roach JC, Hood L, Kosik KS, et al. Origin of the PSEN1 E280A mutation causing early-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S277-S283.e10. PMID 24239249 DOI: 10.1016/j.jalz.2013.09.005  0.88
2013 Henzler CM, Li Z, Dang J, Arcila ML, Zhou H, Liu J, Chang KY, Bassett DS, Rana TM, Kosik KS. Staged miRNA re-regulation patterns during reprogramming. Genome Biology. 14: R149. PMID 24380417 DOI: 10.1186/gb-2013-14-12-r149  0.88
2013 Fong H, Wang C, Knoferle J, Walker D, Balestra ME, Tong LM, Leung L, Ring KL, Seeley WW, Karydas A, Kshirsagar MA, Boxer AL, Kosik KS, Miller BL, Huang Y. Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells. Stem Cell Reports. 1: 226-34. PMID 24319659 DOI: 10.1016/j.stemcr.2013.08.001  0.88
2013 Kosik KS. Diseases: Study neuron networks to tackle Alzheimer's. Nature. 503: 31-2. PMID 24218661 DOI: 10.1038/503031a  0.88
2013 Jammalamadaka A, Banerjee S, Manjunath BS, Kosik KS. Statistical analysis of dendritic spine distributions in rat hippocampal cultures. Bmc Bioinformatics. 14: 287. PMID 24088199 DOI: 10.1186/1471-2105-14-287  0.88
2013 Zhang X, Hernandez I, Rei D, Mair W, Laha JK, Cornwell ME, Cuny GD, Tsai LH, Steen JA, Kosik KS. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. The Journal of Biological Chemistry. 288: 22042-56. PMID 23737518 DOI: 10.1074/jbc.M112.436402  0.88
2013 Giraldo M, Lopera F, Siniard AL, Corneveaux JJ, Schrauwen I, Carvajal J, Muñoz C, Ramirez-Restrepo M, Gaiteri C, Myers AJ, Caselli RJ, Kosik KS, Reiman EM, Huentelman MJ. Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiology of Aging. 34: 2077.e11-8. PMID 23582655 DOI: 10.1016/j.neurobiolaging.2013.02.016  0.88
2013 Smagghe BJ, Stewart AK, Carter MG, Shelton LM, Bernier KJ, Hartman EJ, Calhoun AK, Hatziioannou VM, Lillacci G, Kirk BA, DiNardo BA, Kosik KS, Bamdad C. MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state. Plos One. 8: e58601. PMID 23505541 DOI: 10.1371/journal.pone.0058601  0.88
2013 Kosik KS. Molecular biology: Circles reshape the RNA world. Nature. 495: 322-4. PMID 23446351 DOI: 10.1038/nature11956  0.88
2013 Vélez JI, Chandrasekharappa SC, Henao E, Martinez AF, Harper U, Jones M, Solomon BD, Lopez L, Garcia G, Aguirre-Acevedo DC, Acosta-Baena N, Correa JC, Lopera-Gómez CM, Jaramillo-Elorza MC, Rivera D, ... Kosik KS, et al. Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. Molecular Psychiatry. 18: 568-75. PMID 22710270 DOI: 10.1038/mp.2012.81  0.88
2012 Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gomez MG, Langois CM, Langbaum JB, Ayutyanont N, Roontiva A, Thiyyagura P, Lee W, Mo H, Lopez L, Moreno S, Acosta-Baena N, ... ... Kosik KS, et al. Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study. The Lancet. Neurology. 11: 1057-65. PMID 23137949 DOI: 10.1016/S1474-4422(12)70227-2  0.88
2012 Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, ... ... Kosik KS, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4  0.88
2012 Kosik KS. Tracking the insidious course of Alzheimer's disease Nature Medicine. 18: 1342-1343. PMID 22961163 DOI: 10.1038/nm.2922  0.88
2012 Lalli MA, Garcia G, Madrigal L, Arcos-Burgos M, Arcila ML, Kosik KS, Lopera F. Exploratory data from complete genomes of familial alzheimer disease age-at-onset outliers. Human Mutation. 33: 1630-4. PMID 22829467 DOI: 10.1002/humu.22167  0.88
2012 Conaco C, Bassett DS, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS. Functionalization of a protosynaptic gene expression network. Proceedings of the National Academy of Sciences of the United States of America. 109: 10612-8. PMID 22723359 DOI: 10.1073/pnas.1201890109  0.88
2012 Conaco C, Neveu P, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS. Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions. Bmc Genomics. 13: 209. PMID 22646746 DOI: 10.1186/1471-2164-13-209  0.88
2012 Kosik KS, Rapp PR, Raz N, Small SA, Sweatt JD, Tsai LH. Mechanisms of age-related cognitive change and targets for intervention: epigenetics. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 741-6. PMID 22522509 DOI: 10.1093/gerona/gls110  0.88
2012 Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS. Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Research. 40: 5864-75. PMID 22434881 DOI: 10.1093/nar/gks247  0.88
2012 Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Liu C, Zong H, Rowitch DH, Barres BA, Verma IM, Kosik KS. Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene. 31: 1884-95. PMID 21874051 DOI: 10.1038/onc.2011.380  0.88
2011 Reiman EM, Langbaum JB, Fleisher AS, Caselli RJ, Chen K, Ayutyanont N, Quiroz YT, Kosik KS, Lopera F, Tariot PN. Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments. Journal of Alzheimer's Disease : Jad. 26: 321-9. PMID 21971471 DOI: 10.3233/JAD-2011-0059  0.88
2011 Kye MJ, Neveu P, Lee YS, Zhou M, Steen JA, Sahin M, Kosik KS, Silva AJ. NMDA mediated contextual conditioning changes miRNA expression. Plos One. 6: e24682. PMID 21931811 DOI: 10.1371/journal.pone.0024682  0.88
2011 Kosik KS. PhDs: what's left if science abdicates? Nature. 473: 284. PMID 21593846 DOI: 10.1038/473284b  0.88
2011 Lee EJ, Banerjee S, Zhou H, Jammalamadaka A, Arcila M, Manjunath BS, Kosik KS. Identification of piRNAs in the central nervous system. Rna (New York, N.Y.). 17: 1090-9. PMID 21515829 DOI: 10.1261/rna.2565011  0.88
2011 Laha JK, Zhang X, Qiao L, Liu M, Chatterjee S, Robinson S, Kosik KS, Cuny GD. Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 2098-101. PMID 21353545 DOI: 10.1016/j.bmcl.2011.01.140  0.88
2010 Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, Shraiman BI, Kosik KS. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7: 671-81. PMID 21112562 DOI: 10.1016/j.stem.2010.11.012  0.88
2010 Yuraszeck TM, Neveu P, Rodriguez-Fernandez M, Robinson A, Kosik KS, Doyle FJ. Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology. Plos Computational Biology. 6: e1000997. PMID 21085645 DOI: 10.1371/journal.pcbi.1000997  0.88
2010 Shi Y, Zhao X, Hsieh J, Wichterle H, Impey S, Banerjee S, Neveu P, Kosik KS. MicroRNA regulation of neural stem cells and neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14931-6. PMID 21068294 DOI: 10.1523/JNEUROSCI.4280-10.2010  0.88
2010 Piedrahita D, Hernández I, López-Tobón A, Fedorov D, Obara B, Manjunath BS, Boudreau RL, Davidson B, Laferla F, Gallego-Gómez JC, Kosik KS, Cardona-Gómez GP. Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13966-76. PMID 20962218 DOI: 10.1523/JNEUROSCI.3637-10.2010  0.88
2010 Kosik KS. MicroRNAs and cellular phenotypy. Cell. 143: 21-6. PMID 20887887 DOI: 10.1016/j.cell.2010.09.008  0.88
2010 Srivastava M, Simakov O, Chapman J, Fahey B, Gauthier ME, Mitros T, Richards GS, Conaco C, Dacre M, Hellsten U, Larroux C, Putnam NH, Stanke M, Adamska M, Darling A, ... ... Kosik KS, et al. The Amphimedon queenslandica genome and the evolution of animal complexity. Nature. 466: 720-6. PMID 20686567 DOI: 10.1038/nature09201  0.88
2010 Sakarya O, Conaco C, Egecioglu O, Solla SA, Oakley TH, Kosik KS. Evolutionary expansion and specialization of the PDZ domains. Molecular Biology and Evolution. 27: 1058-69. PMID 20026484 DOI: 10.1093/molbev/msp311  0.88
2009 Banerjee S, Neveu P, Kosik KS. A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation. Neuron. 64: 871-84. PMID 20064393 DOI: 10.1016/j.neuron.2009.11.023  0.88
2009 Fineberg SK, Kosik KS, Davidson BL. MicroRNAs potentiate neural development. Neuron. 64: 303-9. PMID 19914179 DOI: 10.1016/j.neuron.2009.10.020  0.88
2009 Kosik KS. MicroRNAs tell an evo-devo story. Nature Reviews. Neuroscience. 10: 754-9. PMID 19738624 DOI: 10.1038/nrn2713  0.88
2009 Sasaki K, Shimura H, Itaya M, Tanaka R, Mori H, Mizuno Y, Kosik KS, Tanaka S, Hattori N. Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains. Febs Letters. 583: 2194-200. PMID 19527721 DOI: 10.1016/j.febslet.2009.06.015  0.88
2009 Papagiannakopoulos T, Kosik KS. MicroRNA-124: micromanager of neurogenesis. Cell Stem Cell. 4: 375-6. PMID 19427286 DOI: 10.1016/j.stem.2009.04.007  0.88
2009 Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 137: 647-58. PMID 19409607 DOI: 10.1016/j.cell.2009.02.038  0.88
2009 Carrettiero DC, Hernandez I, Neveu P, Papagiannakopoulos T, Kosik KS. The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2151-61. PMID 19228967 DOI: 10.1523/JNEUROSCI.4660-08.2009  0.88
2009 Albensi B, Breen G, Cashikar A, Chai X, Chang R, Cuellar T, Frederikse P, Hayashi M, Hebert S, Kinoshita J, Kosik K, Long J, Maloney B, Mizumoto L, Muresan V, et al. Alzheimer research forum live discussion: Non-coding RNAs in neurodegeneration Journal of Alzheimer's Disease. 16: 441-444. PMID 19221433 DOI: 10.3233/JAD-2009-1007  0.88
2009 Kosik KS. Exploring the early origins of the synapse by comparative genomics. Biology Letters. 5: 108-11. PMID 19049956 DOI: 10.1098/rsbl.2008.0594  0.88
2009 Abu-Elneel K, Liu T, Gazzaniga FS, Nishimura Y, Wall DP, Geschwind DH, Lao K, Kosik KS. Reply to the "letter to the Editors" by Steven Buyske Neurogenetics. 10: 169-170. DOI: 10.1007/s10048-009-0180-6  0.88
2008 Mercer TR, Dinger ME, Mariani J, Kosik KS, Mehler MF, Mattick JS. Noncoding RNAs in Long-Term Memory Formation. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 14: 434-45. PMID 18997122 DOI: 10.1177/1073858408319187  0.88
2008 Hikita ST, Kosik KS, Clegg DO, Bamdad C. MUC1* mediates the growth of human pluripotent stem cells. Plos One. 3: e3312. PMID 18833326 DOI: 10.1371/journal.pone.0003312  0.88
2008 Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Research. 68: 8164-72. PMID 18829576 DOI: 10.1158/0008-5472.CAN-08-1305  0.88
2008 Abu-Elneel K, Ochiishi T, Medina M, Remedi M, Gastaldi L, Caceres A, Kosik KS. A delta-catenin signaling pathway leading to dendritic protrusions. The Journal of Biological Chemistry. 283: 32781-91. PMID 18809680 DOI: 10.1074/jbc.M804688200  0.88
2008 Kosik KS, Lopera F. Genetic testing must recognize impact of bad news on recipient. Nature. 454: 158-9. PMID 18615057 DOI: 10.1038/454158c  0.88
2008 Ochiishi T, Futai K, Okamoto K, Kameyama K, Kosik KS. Regulation of AMPA receptor trafficking by delta-catenin. Molecular and Cellular Neurosciences. 39: 499-507. PMID 18602475 DOI: 10.1016/j.mcn.2008.06.002  0.88
2008 Papagiannakopoulos T, Kosik KS. MicroRNAs: regulators of oncogenesis and stemness. Bmc Medicine. 6: 15. PMID 18577221 DOI: 10.1186/1741-7015-6-15  0.88
2008 Abu-Elneel K, Liu T, Gazzaniga FS, Nishimura Y, Wall DP, Geschwind DH, Lao K, Kosik KS. Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics. 9: 153-61. PMID 18563458 DOI: 10.1007/s10048-008-0133-5  0.88
2008 Sakarya O, Kosik KS, Oakley TH. Reconstructing ancestral genome content based on symmetrical best alignments and Dollo parsimony. Bioinformatics (Oxford, England). 24: 606-12. PMID 18184685 DOI: 10.1093/bioinformatics/btn005  0.88
2007 Glicksman MA, Cuny GD, Liu M, Dobson B, Auerbach K, Stein RL, Kosik KS. New approaches to the discovery of cdk5 inhibitors. Current Alzheimer Research. 4: 547-9. PMID 18220519 DOI: 10.2174/156720507783018181  0.88
2007 Liu T, Papagiannakopoulos T, Puskar K, Qi S, Santiago F, Clay W, Lao K, Lee Y, Nelson SF, Kornblum HI, Doyle F, Petzold L, Shraiman B, Kosik KS. Detection of a microRNA signal in an in vivo expression set of mRNAs. Plos One. 2: e804. PMID 17726534 DOI: 10.1371/journal.pone.0000804  0.88
2007 Kye MJ, Liu T, Levy SF, Xu NL, Groves BB, Bonneau R, Lao K, Kosik KS. Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. Rna (New York, N.Y.). 13: 1224-34. PMID 17592044 DOI: 10.1261/rna.480407  0.88
2007 Sakarya O, Armstrong KA, Adamska M, Adamski M, Wang IF, Tidor B, Degnan BM, Oakley TH, Kosik KS. A post-synaptic scaffold at the origin of the animal kingdom. Plos One. 2: e506. PMID 17551586 DOI: 10.1371/journal.pone.0000506  0.88
2007 Kumar P, Ambasta RK, Veereshwarayya V, Rosen KM, Kosik KS, Band H, Mestril R, Patterson C, Querfurth HW. CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism. Human Molecular Genetics. 16: 848-64. PMID 17317785 DOI: 10.1093/hmg/ddm030  0.88
2006 Kosik KS. The neuronal microRNA system. Nature Reviews. Neuroscience. 7: 911-20. PMID 17115073 DOI: 10.1038/nrn2037  0.88
2006 Kosik KS. Traveling the tau pathway: a personal account. Journal of Alzheimer's Disease : Jad. 9: 251-6. PMID 16914863  0.88
2006 Donahue CP, Muratore C, Wu JY, Kosik KS, Wolfe MS. Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing. The Journal of Biological Chemistry. 281: 23302-6. PMID 16782711 DOI: 10.1074/jbc.C600143200  0.88
2006 Donahue CP, Kosik KS, Shors TJ. Growth hormone is produced within the hippocampus where it responds to age, sex, and stress. Proceedings of the National Academy of Sciences of the United States of America. 103: 6031-6. PMID 16574776 DOI: 10.1073/pnas.0507776103  0.88
2006 Kosik KS. Neuroscience gears up for duel on the issue of brain versus deity. Nature. 439: 138. PMID 16407931 DOI: 10.1038/439138a  0.88
2006 Krichevsky AM, Sonntag KC, Isacson O, Kosik KS. Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells (Dayton, Ohio). 24: 857-64. PMID 16357340 DOI: 10.1634/stemcells.2005-0441  0.88
2005 Kosik KS, Krichevsky AM. The Elegance of the MicroRNAs: A Neuronal Perspective. Neuron. 47: 779-82. PMID 16157272 DOI: 10.1016/j.neuron.2005.08.019  0.88
2005 Kosik KS, Krichevsky AM. Teaching resources. A model for local regulation of translation near active synapses. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr25. PMID 16145019 DOI: 10.1126/stke.3002005tr25  0.88
2005 Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS. MicroRNA profiling of the murine hematopoietic system. Genome Biology. 6: R71. PMID 16086853 DOI: 10.1186/gb-2005-6-8-r71  0.88
2005 Ahn JS, Radhakrishnan ML, Mapelli M, Choi S, Tidor B, Cuny GD, Musacchio A, Yeh LA, Kosik KS. Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation. Chemistry & Biology. 12: 811-23. PMID 16039528 DOI: 10.1016/j.chembiol.2005.05.011  0.88
2005 Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Research. 65: 6029-33. PMID 16024602 DOI: 10.1158/0008-5472.CAN-05-0137  0.88
2005 Rampal R, Arboleda-Velasquez JF, Nita-Lazar A, Kosik KS, Haltiwanger RS. Highly conserved O-fucose sites have distinct effects on Notch1 function. The Journal of Biological Chemistry. 280: 32133-40. PMID 15994302 DOI: 10.1074/jbc.M506104200  0.88
2005 Arboleda-Velasquez JF, Rampal R, Fung E, Darland DC, Liu M, Martinez MC, Donahue CP, Navarro-Gonzalez MF, Libby P, D'Amore PA, Aikawa M, Haltiwanger RS, Kosik KS. CADASIL mutations impair Notch3 glycosylation by Fringe. Human Molecular Genetics. 14: 1631-9. PMID 15857853 DOI: 10.1093/hmg/ddi171  0.88
2005 Kosik KS, Donahue CP, Israely I, Liu X, Ochiishi T. Delta-catenin at the synaptic-adherens junction. Trends in Cell Biology. 15: 172-8. PMID 15752981 DOI: 10.1016/j.tcb.2005.01.004  0.88
2005 Kosik KS, Shimura H. Phosphorylated tau and the neurodegenerative foldopathies. Biochimica Et Biophysica Acta. 1739: 298-310. PMID 15615647 DOI: 10.1016/j.bbadis.2004.10.011  0.88
2005 Krichevsky AM, Kao SC, Tsai LH, Kosik KS. miRNAs in the brain and the application of RNAi to neurons Rna Interference Technology: From Basic Science to Drug Development. 84-100. DOI: 10.1017/CBO9780511546402.008  0.88
2004 Monshausen M, Gehring NH, Kosik KS. The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons. Neuromolecular Medicine. 6: 127-44. PMID 15970630 DOI: 10.1385/NMM:6:2-3:127  0.88
2004 Liu M, Ni J, Kosik KS, Yeh LA. Development of a fluorescent high throughput assay for tau aggregation. Assay and Drug Development Technologies. 2: 609-19. PMID 15674019 DOI: 10.1089/adt.2004.2.609  0.88
2004 Zhu D, Kosik KS, Meigs TE, Yanamadala V, Denker BM. Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau. The Journal of Biological Chemistry. 279: 54983-6. PMID 15525651 DOI: 10.1074/jbc.C400508200  0.88
2004 Ruiz-Opazo N, Kosik KS, Lopez LV, Bagamasbad P, Ponce LR, Herrera VL. Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats. Molecular Medicine (Cambridge, Mass.). 10: 36-44. PMID 15502881  0.88
2004 Alvarez AR, Sandoval PC, Leal NR, Castro PU, Kosik KS. Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species. Neurobiology of Disease. 17: 326-36. PMID 15474370 DOI: 10.1016/j.nbd.2004.06.007  0.88
2004 Israely I, Costa RM, Xie CW, Silva AJ, Kosik KS, Liu X. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Current Biology : Cb. 14: 1657-63. PMID 15380068 DOI: 10.1016/j.cub.2004.08.065  0.88
2004 Morin PJ, Medina M, Semenov M, Brown AM, Kosik KS. Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP. Neurobiology of Disease. 16: 59-67. PMID 15207262 DOI: 10.1016/j.nbd.2004.01.004  0.88
2004 Ahn JS, Musacchio A, Mapelli M, Ni J, Scinto L, Stein R, Kosik KS, Yeh LA. Development of an assay to screen for inhibitors of tau phosphorylation by cdk5. Journal of Biomolecular Screening. 9: 122-31. PMID 15006135 DOI: 10.1177/1087057103260594  0.88
2004 Shimura H, Miura-Shimura Y, Kosik KS. Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival. The Journal of Biological Chemistry. 279: 17957-62. PMID 14963027 DOI: 10.1074/jbc.M400351200  0.88
2004 Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proceedings of the National Academy of Sciences of the United States of America. 101: 360-5. PMID 14691248 DOI: 10.1073/pnas.2333854100  0.88
2004 Donahue CP, Kosik KS. Distribution pattern of Notch3 mutations suggests a gain-of-function mechanism for CADASIL. Genomics. 83: 59-65. PMID 14667809 DOI: 10.1016/S0888-7543(03)00206-4  0.88
2004 Shimura H, Schwartz D, Gygi SP, Kosik KS. CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. The Journal of Biological Chemistry. 279: 4869-76. PMID 14612456 DOI: 10.1074/jbc.M305838200  0.88
2004 Kao SC, Krichevsky AM, Kosik KS, Tsai LH. BACE1 suppression by RNA interference in primary cortical neurons. The Journal of Biological Chemistry. 279: 1942-9. PMID 14600149 DOI: 10.1074/jbc.M309219200  0.88
2003 Krichevsky AM, King KS, Donahue CP, Khrapko K, Kosik KS. A microRNA array reveals extensive regulation of microRNAs during brain development. Rna (New York, N.Y.). 9: 1274-81. PMID 13130141 DOI: 10.1261/rna.5980303  0.88
2003 Pastor P, Roe CM, Villegas A, Bedoya G, Chakraverty S, García G, Tirado V, Norton J, Ríos S, Martínez M, Kosik KS, Lopera F, Goate AM. Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. Annals of Neurology. 54: 163-9. PMID 12891668 DOI: 10.1002/ana.10636  0.88
2003 Martinez MC, Ochiishi T, Majewski M, Kosik KS. Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. The Journal of Cell Biology. 162: 99-111. PMID 12835311 DOI: 10.1083/jcb.200211025  0.88
2003 Kosik KS. Beyond phrenology, at last. Nature Reviews. Neuroscience. 4: 234-9. PMID 12612636 DOI: 10.1038/nrn1053  0.88
2002 Donahue CP, Jensen RV, Ochiishi T, Eisenstein I, Zhao M, Shors T, Kosik KS. Transcriptional profiling reveals regulated genes in the hippocampus during memory formation. Hippocampus. 12: 821-33. PMID 12542233 DOI: 10.1002/hipo.10058  0.88
2002 Kosik KS, Ahn J, Stein R, Yeh LA. Discovery of compounds that will prevent tau pathology. Journal of Molecular Neuroscience : Mn. 19: 261-6. PMID 12540051 DOI: 10.1385/JMN:19:3:261  0.88
2002 Temple MD, Kosik KS, Steward O. Spatial learning and memory is preserved in rats after early development in a microgravity environment. Neurobiology of Learning and Memory. 78: 199-216. PMID 12431413 DOI: 10.1006/nlme.2001.4049  0.88
2002 Martin KC, Kosik KS. Synaptic tagging -- who's it? Nature Reviews. Neuroscience. 3: 813-20. PMID 12360325 DOI: 10.1038/nrn942  0.88
2002 Krichevsky AM, Kosik KS. RNAi functions in cultured mammalian neurons. Proceedings of the National Academy of Sciences of the United States of America. 99: 11926-9. PMID 12192088 DOI: 10.1073/pnas.182272699  0.88
2002 Arboleda-Velasquez JF, Lopera F, Lopez E, Frosch MP, Sepulveda-Falla D, Gutierrez JE, Vargas S, Medina M, Martinez De Arrieta C, Lebo RV, Slaugenhaupt SA, Betensky RA, Villegas A, Arcos-Burgos M, Rivera D, ... ... Kosik KS, et al. C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke. Neurology. 59: 277-9. PMID 12136071  0.88
2002 Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. The American Journal of Pathology. 160: 1655-67. PMID 12000718 DOI: 10.1016/S0002-9440(10)61113-3  0.88
2002 Kosik KS, Krichevsky AM. The message and the messenger: delivering RNA in neurons. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe16. PMID 11930084 DOI: 10.1126/stke.2002.126.pe16  0.88
2002 Lu Q, Mukhopadhyay NK, Griffin JD, Paredes M, Medina M, Kosik KS. Brain armadillo protein delta-catenin interacts with Abl tyrosine kinase and modulates cellular morphogenesis in response to growth factors. Journal of Neuroscience Research. 67: 618-24. PMID 11891774 DOI: 10.1002/jnr.10151  0.88
2002 Laura RP, Witt AS, Held HA, Gerstner R, Deshayes K, Koehler MF, Kosik KS, Sidhu SS, Lasky LA. The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. The Journal of Biological Chemistry. 277: 12906-14. PMID 11821434 DOI: 10.1074/jbc.M200818200  0.88
2001 Krichevsky AM, Kosik KS. Neuronal RNA granules: A link between RNA localization and stimulation-dependent translation Neuron. 32: 683-696. PMID 11719208 DOI: 10.1016/S0896-6273(01)00508-6  0.88
2001 Neumann PJ, Araki SS, Arcelus A, Longo A, Papadopoulos G, Kosik KS, Kuntz KM, Bhattacharjya A. Measuring Alzheimer's disease progression with transition probabilities: estimates from CERAD. Neurology. 57: 957-64. PMID 11571317  0.88
2001 Neumann PJ, Hammitt JK, Mueller C, Fillit HM, Hill J, Tetteh NA, Kosik KS. Public attitudes about genetic testing for alzheimer's disease Health Affairs. 20: 252-264. PMID 11558711  0.88
2001 Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science (New York, N.Y.). 293: 263-9. PMID 11431533 DOI: 10.1126/science.1060627  0.88
2001 Johnson KA, Lopera F, Jones K, Becker A, Sperling R, Hilson J, Londono J, Siegert I, Arcos M, Moreno S, Madrigal L, Ossa J, Pineda N, Ardila A, Roselli M, ... ... Kosik KS, et al. Presenilin-1-associated abnormalities in regional cerebral perfusion. Neurology. 56: 1545-51. PMID 11402113  0.88
2001 Kunda P, Paglini G, Quiroga S, Kosik K, Cáceres A. Evidence for the involvement of Tiam1 in axon formation Journal of Neuroscience. 21: 2361-2372. PMID 11264310  0.88
2001 Kosik KS. The high flying genome Bioessays. 23: 203-205. PMID 11169594 DOI: 10.1002/1521-1878(200102)23:2<203::AID-BIES1028>3.0.CO;2-J  0.88
2001 Lu M, Kosik KS. Competition for microtubule-binding with dual expression of tau missense and splice isoforms Molecular Biology of the Cell. 12: 171-184. PMID 11160831  0.88
2000 Ardila A, Lopera F, Rosselli M, Moreno S, Madrigal L, Arango-Lasprilla JC, Arcos M, Murcia C, Arango-Viana JC, Ossa J, Goate A, Kosik KS. Neuropsychological profile of a large kindred with familial Alzheimer's disease caused by the E280A single presenilin-1 mutation. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 15: 515-28. PMID 14590205 DOI: 10.1016/S0887-6177(99)00041-4  0.88
2000 Kosik KS. The long reach of evolution and development: Effects on the Alzheimer brain Annals of the New York Academy of Sciences. 924: 76-80. PMID 11193805  0.88
2000 Noll E, Medina M, Hartley D, Zhou J, Perrimon N, Kosik KS. Presenilin affects arm/beta-catenin localization and function in Drosophila. Developmental Biology. 227: 450-64. PMID 11071766 DOI: 10.1006/dbio.2000.9925  0.88
2000 Rosselli MC, Ardila AC, Moreno SC, Standish VC, Arango-Lasprilla JC, Tirado VM, Ossa JM, Goate AM, Kosik KS, Lopera F. Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study. Journal of Clinical and Experimental Neuropsychology. 22: 483-95. PMID 10923058 DOI: 10.1076/1380-3395(200008)22:4;1-0;FT483  0.88
2000 Ho C, Zhou J, Medina M, Goto T, Jacobson M, Bhide PG, Kosik KS. δ-Catenin is a nervous system-specific adherens junction protein which undergoes dynamic relocalization during development Journal of Comparative Neurology. 420: 261-276. PMID 10753311 DOI: 10.1002/(SICI)1096-9861(20000501)420:2<261::AID-CNE8>3.0.CO;2-Q  0.88
2000 Medina M, Marinescu RC, Overhauser J, Kosik KS. Hemizygosity of δ-catenin (CTNND2) is associated with severe mental retardation in cri-du-chat syndrome Genomics. 63: 157-164. PMID 10673328 DOI: 10.1006/geno.1999.6090  0.88
2000 Lansbury PT, Kosik KS. Neurodegeneration: new clues on inclusions. Chemistry & Biology. 7: R9-R12. PMID 10662685 DOI: 10.1016/S1074-5521(00)00068-5  0.88
2000 Rook MS, Lu M, Kosik KS. CaMKIIα 3' untranslated region-directed mRNA translocation in living neurons: Visualization by GFP linkage Journal of Neuroscience. 20: 6385-6393.  0.88
1999 Kosik KS. A notable cleavage: Winding up with β-amyloid Proceedings of the National Academy of Sciences of the United States of America. 96: 2574-2576. PMID 10077548 DOI: 10.1073/pnas.96.6.2574  0.88
1999 Lu Q, Paredes M, Medina M, Zhou J, Cavallo R, Peifer M, Orecchio L, Kosik KS. delta-catenin, an adhesive junction-associated protein which promotes cell scattering. The Journal of Cell Biology. 144: 519-32. PMID 9971746 DOI: 10.1083/jcb.144.3.519  0.88
1999 Kosik KS. A partnership that delivers Nature Medicine. 5: 149-150. PMID 9930858 DOI: 10.1038/5510  0.88
1998 Kosik KS. Neurolab: learning how the nervous system adapts to microgravity Neuroscience News. 5: 36-38. PMID 12053888  0.88
1998 Paglini G, Kunda P, Quiroga S, Kosik K, Cáceres A. Suppression of radixin and moesin alters growth cone morphology, motility, and process formation in primary cultured neurons Journal of Cell Biology. 143: 443-455. PMID 9786954 DOI: 10.1083/jcb.143.2.443  0.88
1998 Lee SJ, Liyanage U, Bickel PE, Xia W, Lansbury PT, Kosik KS. A detergent-insoluble membrane compartment contains A beta in vivo. Nature Medicine. 4: 730-4. PMID 9623986 DOI: 10.1038/nm0698-730  0.88
1998 Lu Q, Paredes M, Zhang J, Kosik KS. Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions. Molecular and Cellular Biology. 18: 3257-65. PMID 9584166  0.88
1998 Ferreira A, Chin LS, Li L, Lanier LM, Kosik KS, Greengard P. Distinct roles of synapsin I and synapsin II during neuronal development. Molecular Medicine (Cambridge, Mass.). 4: 22-8. PMID 9513186  0.88
1998 Kosik KS, Tanzi RE, Finch CE. Presenilin interactions and Alzheimer's disease [6] (multiple letters) Science. 279: 463-465. PMID 9454341  0.88
1998 Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS. Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 251-65. PMID 9412505  0.88
1998 Kosik KS. Too broad a perspective? Molecular Medicine Today. 4: 58. DOI: 10.1016/S1357-4310(97)01165-9  0.88
1997 Hall GF, Yao J, Selzer ME, Kosik KS. Cytoskeletal changes correlated with the loss of neuronal polarity in axotomized lamprey central neurons. Journal of Neurocytology. 26: 733-53. PMID 9426171 DOI: 10.1023/A:1018562331003  0.88
1997 Knowles RB, Kosik KS. Neurotrophin-3 signals redistribute RNA in neurons Proceedings of the National Academy of Sciences of the United States of America. 94: 14804-14808. PMID 9405694 DOI: 10.1073/pnas.94.26.14804  0.88
1997 Lu M, Witke W, Kwiatkowski DJ, Kosik KS. Delayed retraction of filopodia in gelsolin null mice Journal of Cell Biology. 138: 1279-1287. PMID 9298983 DOI: 10.1083/jcb.138.6.1279  0.88
1997 Lendon CL, Martinez A, Behrens IM, Kosik KS, Madrigal L, Norton J, Neuman R, Myers A, Busfield F, Wragg M, Arcos M, Arango Viana JC, Ossa J, Ruiz A, Goate AM, et al. E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles. Human Mutation. 10: 186-95. PMID 9298817 DOI: 10.1002/(SICI)1098-1004(1997)10:3<186::AID-HUMU2>3.0.CO;2-H  0.88
1997 Flanagan LA, Cunningham CC, Chen J, Prestwich GD, Kosik KS, Janmey PA. The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau Biophysical Journal. 73: 1440-1447. PMID 9284311  0.88
1997 Morfini G, Quiroga S, Rosa A, Kosik K, Cáceres A. Suppression of KIF2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension Journal of Cell Biology. 138: 657-669. PMID 9245793 DOI: 10.1083/jcb.138.3.657  0.88
1997 Ferreira A, Lu Q, Orecchio L, Kosik KS. Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar aβ Molecular and Cellular Neurosciences. 9: 220-234. PMID 9245504 DOI: 10.1006/mcne.1997.0615  0.88
1997 Zhou J, Liyanage U, Medina M, Ho C, Simmons AD, Lovett M, Kosik KS. Presenilin 1 interaction in the brain with a novel member of the Armadillo family. Neuroreport. 8: 2085-90. PMID 9223106  0.88
1997 Zhou J, Liyanage U, Medina M, Ho C, Simmons AD, Lovett M, Kosik KS. Presenilin 1 interaction in the brain with a novel member of the Armadillo family. Neuroreport. 8: 1489-94. PMID 9172160  0.88
1997 Lopera F, Ardilla A, Martínez A, Madrigal L, Arango-Viana JC, Lemere CA, Arango-Lasprilla JC, Hincapíe L, Arcos-Burgos M, Ossa JE, Behrens IM, Norton J, Lendon C, Goate AM, Ruiz-Linares A, ... ... Kosik KS, et al. Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation. Jama. 277: 793-9. PMID 9052708  0.88
1997 Cunningham CC, Leclerc N, Flanagan LA, Lu M, Janmey PA, Kosik KS. Microtubule-associated protein 2c reorganizes both microtubules and microfilaments into distinct cytological structures in an actin-binding protein-280-deficient melanoma cell line Journal of Cell Biology. 136: 845-857. PMID 9049250 DOI: 10.1083/jcb.136.4.845  0.88
1996 Ferreira A, Li L, Chin LS, Greengard P, Kosik KS. Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons Molecular and Cellular Neurosciences. 8: 286-299. PMID 9026316 DOI: 10.1006/mcne.1996.0064  0.88
1996 Knowles RB, Sabry JH, Martone ME, Deerinck TJ, Ellisman MH, Bassell GJ, Kosik KS. Translocation of RNA granules in living neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7812-20. PMID 8987809  0.88
1996 Leclerc N, Baas PW, Garner CC, Kosik KS. Juvenile and mature MAP2 isoforms induce distinct patterns of process outgrowth. Molecular Biology of the Cell. 7: 443-55. PMID 8868472  0.88
1996 DiTella MC, Feiguin F, Carri N, Kosik KS, Cáceres A. MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth Journal of Cell Science. 109: 467-477. PMID 8838670  0.88
1996 Lemere CA, Lopera F, Kosik KS, Lendon CL, Ossa J, Saido TC, Yamaguchi H, Ruiz A, Martinez A, Madrigal L, Hincapie L, Arango JC, Anthony DC, Koo EH, Goate AM, et al. The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology. Nature Medicine. 2: 1146-50. PMID 8837617 DOI: 10.1038/nm1096-1146  0.88
1996 Morishima-Kawashima M, Kosik KS. The pool of MAP kinase associated with microtubules is small but constitutively active Molecular Biology of the Cell. 7: 893-905. PMID 8816996  0.88
1996 Ferreira A, Kosik KS. Accelerated neuronal differentiation induced by p53 suppression Journal of Cell Science. 109: 1509-1516. PMID 8799837  0.88
1996 Andreadis A, Wagner BK, Broderick JA, Kosik KS. A tau promoter region without neuronal specificity. Journal of Neurochemistry. 66: 2257-63. PMID 8632146  0.88
1996 Kosik KS, Qiu WQ, Greenberg S. Cellular signaling pathways and cytoskeletal organization Annals of the New York Academy of Sciences. 777: 114-120. PMID 8624073  0.88
1995 Mercken M, Fischer I, Kosik KS, Nixon RA. Three distinct axonal transport rates for tau, tubulin, and other microtubule-associated proteins: evidence for dynamic interactions of tau with microtubules in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 8259-67. PMID 8613759  0.88
1995 Greenberg SM, Qiu WQ, Selkoe DJ, Ben-Itzhak A, Kosik KS. Amino-terminal region of the beta-amyloid precursor protein activates mitogen-activated protein kinase. Neuroscience Letters. 198: 52-6. PMID 8570096 DOI: 10.1016/0304-3940(95)11944-R  0.88
1995 Chin LS, Li L, Ferreira A, Kosik KS, Greengard P. Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 92: 9230-9234. PMID 7568107 DOI: 10.1073/pnas.92.20.9230  0.88
1995 Ferreira A, Han HQ, Greengard P, Kosik KS. Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture Proceedings of the National Academy of Sciences of the United States of America. 92: 9225-9229. PMID 7568106 DOI: 10.1073/pnas.92.20.9225  0.88
1995 Andreadis A, Broderick JA, Kosik KS. Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons Nucleic Acids Research. 23: 3585-3593. PMID 7567473  0.88
1995 Greenberg SM, Kosik KS. Secreted β-APP stimulates MAP kinase and phosphorylation of tau in neurons Neurobiology of Aging. 16: 403-407. PMID 7566349 DOI: 10.1016/0197-4580(94)00172-W  0.88
1995 Amaratunga A, Leeman SE, Kosik KS, Fine RE. Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon. Journal of Neurochemistry. 64: 2374-6. PMID 7536813  0.88
1995 Greenberg SM, Kosik KS. Authors' response to commentary Neurobiology of Aging. 16: 408. DOI: 10.1016/0197-4580(94)00174-Y  0.88
1994 Feiguin F, Ferreira A, Kosik KS, Caceres A. Kinesin-mediated organelle translocation revealed by specific cellular manipulations Journal of Cell Biology. 127: 1021-1039. PMID 7962067 DOI: 10.1083/jcb.127.4.1021  0.88
1994 Kosik KS. The Alzheimer's disease sphinx: A riddle with plaques and tangles Journal of Cell Biology. 127: 1501-1504. PMID 7798306 DOI: 10.1083/jcb.127.6.1501  0.88
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