Thomas Weimbs - Publications

Affiliations: 
2005- Department of Molecular, Cellular, and Developmental Biology University of California, Santa Barbara, Santa Barbara, CA, United States 
Website:
https://labs.mcdb.ucsb.edu/weimbs/thomas/

60/63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Giovannone AJ, Reales E, Bhattaram P, Nackeeran S, Monahan AB, Syed R, Weimbs T. The H domain of syntaxin 3 is a ubiquitin binding domain. Scientific Reports. 10: 21350. PMID 33288783 DOI: 10.1038/s41598-020-78412-0  0.72
2020 Dafinger C, Mandel AM, Braun A, Göbel H, Burgmaier K, Massella L, Mastrangelo A, Dötsch J, Benzing T, Weimbs T, Schermer B, Liebau MC. The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation. Journal of Cellular and Molecular Medicine. PMID 33112055 DOI: 10.1111/jcmm.16014  0.36
2020 Strubl S, Torres JA, Spindt AK, Pellegrini H, Liebau MC, Weimbs T. STAT signaling in polycystic kidney disease. Cellular Signalling. 72: 109639. PMID 32325185 DOI: 10.1016/j.cellsig.2020.109639  0.6
2019 Torres JA, Kruger SL, Broderick C, Amarlkhagva T, Agrawal S, Dodam JR, Mrug M, Lyons LA, Weimbs T. Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease. Cell Metabolism. PMID 31631001 DOI: 10.1016/j.cmet.2019.09.012  0.72
2019 Torres JA, Rezaei M, Broderick C, Lin L, Wang X, Hoppe B, Cowley BD, Savica V, Torres VE, Khan S, Holmes RP, Mrug M, Weimbs T. Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease. The Journal of Clinical Investigation. 130. PMID 31361604 DOI: 10.1172/JCI128503  0.6
2018 Weimbs T, Shillingford JM, Torres J, Kruger SL, Bourgeois BC. Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. Clinical Kidney Journal. 11: i27-i38. PMID 30581563 DOI: 10.1093/ckj/sfy089  0.72
2018 Kipp KR, Kruger SL, Schimmel MF, Parker N, Shillingford JM, Leamon CP, Weimbs T. Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease. American Journal of Physiology. Renal Physiology. PMID 29717938 DOI: 10.1152/ajprenal.00057.2018  0.72
2018 Giovannone AJ, Reales E, Bhattaram P, Fraile-Ramos A, Weimbs T. Tracking Endocytosis and Intracellular Trafficking of Epitope-tagged Syntaxin 3 by Antibody Feeding in Live, Polarized MDCK Cells. Bio-Protocol. 8. PMID 29564371 DOI: 10.21769/BioProtoc.2453  0.72
2018 Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouze C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, et al. Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8. American Journal of Physiology. Renal Physiology. PMID 29537311 DOI: 10.1152/ajprenal.00489.2017  0.32
2018 Olsan EE, West JD, Torres JA, Doerr N, Weimbs T. Identification of Targets of Interleukin-13 and Signal Transducer and Activator of Transcription-6 (STAT6) Signaling in Polycystic Kidney Disease. American Journal of Physiology. Renal Physiology. PMID 29513071 DOI: 10.1152/ajprenal.00346.2017  0.72
2018 Giovannone AJ, Winterstein C, Bhattaram P, Reales E, Low SH, Baggs JE, Xu M, Lalli MA, Hogenesch JB, Weimbs T. Soluble syntaxin 3 functions as a transcriptional regulator. The Journal of Biological Chemistry. PMID 29475951 DOI: 10.1074/jbc.RA117.000874  0.72
2017 Giovannone AJ, Reales E, Bhattaram P, Fraile-Ramos A, Weimbs T. Mono-ubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes. Molecular Biology of the Cell. PMID 28814500 DOI: 10.1091/mbc.E17-07-0461  0.72
2016 Soo Hoo L, Banna CD, Radeke CM, Sharma N, Albertolle ME, Low SH, Weimbs T, Vandenberg CA. The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. Plos One. 11: e0163671. PMID 27662481 DOI: 10.1371/journal.pone.0163671  0.4
2016 Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T. Regulation of Polycystin-1 Function by Calmodulin Binding. Plos One. 11: e0161525. PMID 27560828 DOI: 10.1371/journal.pone.0161525  0.6
2016 Kipp KR, Rezaei M, Lin L, Dewey EC, Weimbs T. A mild reduction of food intake slows disease progression in an orthologous mouse model of polycystic kidney disease. American Journal of Physiology. Renal Physiology. ajprenal.00551.2015. PMID 26764208 DOI: 10.1152/ajprenal.00551.2015  0.6
2015 Rothé B, Leal-Esteban L, Bernet F, Urfer S, Doerr N, Weimbs T, Iwaszkiewicz J, Constam DB. Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA. Molecular and Cellular Biology. 35: 3339-53. PMID 26217012 DOI: 10.1128/MCB.00341-15  0.88
2015 Olsan EE, Matsushita T, Rezaei M, Weimbs T. Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease. The Journal of Biological Chemistry. 290: 15679-86. PMID 25922073 DOI: 10.1074/jbc.M114.607929  0.88
2014 Talbot JJ, Song X, Wang X, Rinschen MM, Doerr N, LaRiviere WB, Schermer B, Pei YP, Torres VE, Weimbs T. The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation. Journal of the American Society of Nephrology : Jasn. 25: 1737-48. PMID 24578126 DOI: 10.1681/ASN.2013091026  0.88
2013 Weimbs T, Talbot JJ. STAT3 Signaling in Polycystic Kidney Disease. Drug Discovery Today. Disease Mechanisms. 10: e113-e118. PMID 26523147 DOI: 10.1016/j.ddmec.2013.03.001  0.88
2013 Weimbs T, Olsan EE, Talbot JJ. Regulation of STATs by polycystin-1 and their role in polycystic kidney disease. Jak-Stat. 2: e23650. PMID 24058808 DOI: 10.4161/jkst.23650  0.88
2012 Shillingford JM, Leamon CP, Vlahov IR, Weimbs T. Folate-conjugated rapamycin slows progression of polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 23: 1674-81. PMID 22859856 DOI: 10.1681/ASN.2012040367  0.88
2012 Stayner C, Shields J, Slobbe L, Shillingford JM, Weimbs T, Eccles MR. Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus. Nephrology (Carlton, Vic.). 17: 739-47. PMID 22725947 DOI: 10.1111/j.1440-1797.2012.01639.x  0.88
2011 Olsan EE, Mukherjee S, Wulkersdorfer B, Shillingford JM, Giovannone AJ, Todorov G, Song X, Pei Y, Weimbs T. Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 18067-72. PMID 22025716 DOI: 10.1073/pnas.1111966108  0.88
2011 Reales E, Sharma N, Low SH, Fölsch H, Weimbs T. Basolateral sorting of syntaxin 4 is dependent on its N-terminal domain and the AP1B clathrin adaptor, and required for the epithelial cell polarity. Plos One. 6: e21181. PMID 21698262 DOI: 10.1371/journal.pone.0021181  0.88
2011 Talbot JJ, Shillingford JM, Vasanth S, Doerr N, Mukherjee S, Kinter MT, Watnick T, Weimbs T. Polycystin-1 regulates STAT activity by a dual mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 7985-90. PMID 21518865 DOI: 10.1073/pnas.1103816108  0.88
2011 Weimbs T. Third-hit signaling in renal cyst formation. Journal of the American Society of Nephrology : Jasn. 22: 793-5. PMID 21493772 DOI: 10.1681/ASN.2011030284  0.88
2010 Torres VE, Boletta A, Chapman A, Gattone V, Pei Y, Qian Q, Wallace DP, Weimbs T, Wüthrich RP. Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases. Clinical Journal of the American Society of Nephrology : Cjasn. 5: 1312-29. PMID 20498248 DOI: 10.2215/CJN.01360210  0.88
2010 Shillingford JM, Piontek KB, Germino GG, Weimbs T. Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1. Journal of the American Society of Nephrology : Jasn. 21: 489-97. PMID 20075061 DOI: 10.1681/ASN.2009040421  0.88
2009 Mistry AC, Mallick R, Klein JD, Weimbs T, Sands JM, Fröhlich O. Syntaxin specificity of aquaporins in the inner medullary collecting duct. American Journal of Physiology. Renal Physiology. 297: F292-300. PMID 19515809 DOI: 10.1152/ajprenal.00196.2009  0.88
2007 Weimbs T. Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1. American Journal of Physiology. Renal Physiology. 293: F1423-32. PMID 17715262 DOI: 10.1152/ajprenal.00275.2007  0.88
2007 Dai S, Zhang Y, Weimbs T, Yaffe MB, Zhou D. Bacteria-generated PtdIns(3)P recruits VAMP8 to facilitate phagocytosis. Traffic (Copenhagen, Denmark). 8: 1365-74. PMID 17645435 DOI: 10.1111/j.1600-0854.2007.00613.x  0.88
2006 Weimbs T. Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair? Cell Cycle (Georgetown, Tex.). 5: 2425-9. PMID 17102641  0.88
2006 Christiansen JJ, Weimbs T, Bander N, Rajasekaran AK. Differing effects of microtubule depolymerizing and stabilizing chemotherapeutic agents on t-SNARE-mediated apical targeting of prostate-specific membrane antigen. Molecular Cancer Therapeutics. 5: 2468-73. PMID 17041090 DOI: 10.1158/1535-7163.MCT-06-0253  0.88
2006 Kidd GJ, Yadav VK, Huang P, Brand SL, Low SH, Weimbs T, Trapp BD. A dual tyrosine-leucine motif mediates myelin protein P0 targeting in MDCK cells. Glia. 54: 135-45. PMID 16788992 DOI: 10.1002/glia.20366  0.88
2006 Sharma N, Low SH, Misra S, Pallavi B, Weimbs T. Apical targeting of syntaxin 3 is essential for epithelial cell polarity. The Journal of Cell Biology. 173: 937-48. PMID 16785322 DOI: 10.1083/jcb.200603132  0.88
2006 Shillingford JM, Murcia NS, Larson CH, Low SH, Hedgepeth R, Brown N, Flask CA, Novick AC, Goldfarb DA, Kramer-Zucker A, Walz G, Piontek KB, Germino GG, Weimbs T. The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 5466-71. PMID 16567633 DOI: 10.1073/pnas.0509694103  0.88
2006 Low SH, Vasanth S, Larson CH, Mukherjee S, Sharma N, Kinter MT, Kane ME, Obara T, Weimbs T. Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease. Developmental Cell. 10: 57-69. PMID 16399078 DOI: 10.1016/j.devcel.2005.12.005  0.88
2006 Low SH, Vasanji A, Nanduri J, He M, Sharma N, Koo M, Drazba J, Weimbs T. Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. Molecular Biology of the Cell. 17: 977-89. PMID 16339081 DOI: 10.1091/mbc.E05-05-0462  0.88
2005 Fei B, Flask C, Wang H, Pi A, Wilson D, Shillingford J, Murcia N, Weimbs T, Duerk J. Image Segmentation, Registration and Visualization of Serial MR Images for Therapeutic Assessment of Polycystic Kidney Disease in Transgenic Mice. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 467-9. PMID 17282217 DOI: 10.1109/IEMBS.2005.1616448  0.88
2004 Tartakoff AM, Matera AG, Pimplikar SW, Weimbs T. Regulation of nuclear functions--nucleocytoplasmic transport in context. European Journal of Cell Biology. 83: 185-92. PMID 15346808 DOI: 10.1078/0171-9335-00386  0.88
2004 Fan S, Hurd TW, Liu CJ, Straight SW, Weimbs T, Hurd EA, Domino SE, Margolis B. Polarity proteins control ciliogenesis via kinesin motor interactions. Current Biology : Cb. 14: 1451-61. PMID 15324661 DOI: 10.1016/j.cub.2004.08.025  0.88
2003 Weimbs T, Low SH, Li X, Kreitzer G. SNAREs and epithelial cells. Methods (San Diego, Calif.). 30: 191-7. PMID 12798133 DOI: 10.1016/S1046-2023(03)00025-2  0.88
2003 Low SH, Li X, Miura M, Kudo N, Quiñones B, Weimbs T. Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells. Developmental Cell. 4: 753-9. PMID 12737809 DOI: 10.1016/S1534-5807(03)00122-9  0.88
2003 Sherief MH, Low SH, Miura M, Kudo N, Novick AC, Weimbs T. Matrix metalloproteinase activity in urine of patients with renal cell carcinoma leads to degradation of extracellular matrix proteins: possible use as a screening assay. The Journal of Urology. 169: 1530-4. PMID 12629409 DOI: 10.1097/01.ju.0000049201.91150.9d  0.88
2003 Kreitzer G, Schmoranzer J, Low SH, Li X, Gan Y, Weimbs T, Simon SM, Rodriguez-Boulan E. Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells. Nature Cell Biology. 5: 126-36. PMID 12545172 DOI: 10.1038/ncb917  0.88
2002 Low SH, Marmorstein LY, Miura M, Li X, Kudo N, Marmorstein AD, Weimbs T. Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype. Journal of Cell Science. 115: 4545-53. PMID 12414999 DOI: 10.1242/jcs.00116  0.88
2002 Li X, Low SH, Miura M, Weimbs T. SNARE expression and localization in renal epithelial cells suggest mechanism for variability of trafficking phenotypes. American Journal of Physiology. Renal Physiology. 283: F1111-22. PMID 12372788 DOI: 10.1152/ajprenal.00185.2002  0.88
2002 van IJzendoorn SC, Tuvim MJ, Weimbs T, Dickey BF, Mostov KE. Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Developmental Cell. 2: 219-28. PMID 11832247 DOI: 10.1016/S1534-5807(02)00115-6  0.88
2001 Lim SN, Bonzelius F, Seng Hui Low, Wille H, Weimbs T, Herman GA. Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins Molecular Biology of the Cell. 12: 981-995. PMID 11294901  0.88
2000 Low SH, Miura M, Roche PA, Valdez AC, Mostov KE, Weimbs T. Intracellular redirection of plasma membrane trafficking after loss of epithelial cell polarity. Molecular Biology of the Cell. 11: 3045-60. PMID 10982399  0.88
1998 Weimbs T, Mostov K, Hui Low S, Hofmann K. A model for structural similarity between different SNARE complexes based on sequence relationships [1] Trends in Cell Biology. 8: 260-262. PMID 9714596 DOI: 10.1016/S0962-8924(98)01285-9  0.88
1998 Low SH, Chapin SJ, Wimmer C, Whiteheart SW, Kömüves LG, Mostov KE, Weimbs T. The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells. The Journal of Cell Biology. 141: 1503-13. PMID 9647644 DOI: 10.1083/jcb.141.7.1503  0.88
1998 Low SH, Roche PA, Anderson HA, van Ijzendoorn SC, Zhang M, Mostov KE, Weimbs T. Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells. The Journal of Biological Chemistry. 273: 3422-30. PMID 9452464 DOI: 10.1074/jbc.273.6.3422  0.88
1997 Weimbs T, Low SH, Chapin SJ, Mostov KE. Apical targeting in polarized epithelial cells: There's more afloat than rafts. Trends in Cell Biology. 7: 393-9. PMID 17708988 DOI: 10.1016/S0962-8924(97)01130-6  0.88
1997 Weimbs T, Low SH, Chapin SJ, Mostov KE, Bucher P, Hofmann K. A conserved domain is present in different families of vesicular fusion proteins: a new superfamily. Proceedings of the National Academy of Sciences of the United States of America. 94: 3046-51. PMID 9096343 DOI: 10.1073/pnas.94.7.3046  0.88
1997 Weimbs T, Ljllow S, Chapin K, Mostov K, Bucher P, Hofmann K. The t-snare domain, a conserved coiled-coil domain present in different families of vesicular fusion proteins, defines a new superfamily Faseb Journal. 11: A1064.  0.88
1996 Low SH, Chapin SJ, Weimbs T, Kömüves LG, Bennett MK, Mostov KE. Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells. Molecular Biology of the Cell. 7: 2007-18. PMID 8970161  0.88
1995 Mostov KE, Altschuler Y, Chapin SJ, Enrich C, Low SH, Luton F, Richman-Eisenstat J, Singer KL, Tang K, Weimbs T. Regulation of protein traffic in polarized epithelial cells: the polymeric immunoglobulin receptor model. Cold Spring Harbor Symposia On Quantitative Biology. 60: 775-81. PMID 8824452  0.88
1994 Weimbs T, Stoffel W. Topology of CNS myelin proteolipid protein: Evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals Biochemistry. 33: 10408-10415. PMID 7520754  1
1992 Weimbs T, Stoffel W. Proteolipid protein (PLP) of CNS myelin: Positions of free, disulfide- bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP Biochemistry. 31: 12289-12296. PMID 1281423 DOI: 10.1021/bi00164a002  1
Low-probability matches
2019 Weimbs T. Preface. Methods in Cell Biology. 154: xiii-xiv. PMID 31493824 DOI: 10.1016/S0091-679X(19)30115-3  0.01
2019 Weimbs T. Preface. Methods in Cell Biology. 153: xiii-xiv. PMID 31395387 DOI: 10.1016/S0091-679X(19)30104-9  0.01
2018 Weimbs T. Are Cyst-Associated Macrophages in Polycystic Kidney Disease the Equivalent to TAMs in Cancer? Journal of the American Society of Nephrology : Jasn. PMID 30209077 DOI: 10.1681/ASN.2018080846  0.01
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