Thales Papagiannakopoulos, Ph.D. - Publications

Affiliations: 
2010 Molecular, Cellular & Developmental Biology University of California, Santa Barbara, Santa Barbara, CA, United States 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Marzio A, Kurz E, Sahni JM, Di Feo G, Puccini J, Jiang S, Hirsch CA, Arbini AA, Wu WL, Pass HI, Bar-Sagi D, Papagiannakopoulos T, Pagano M. EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion. Cell. PMID 34963055 DOI: 10.1016/j.cell.2021.12.005  0.306
2021 Ciampricotti M, Karakousi T, Richards AL, Quintanal-Villalonga A, Karatza A, Caeser R, Costa EA, Allaj V, Manoj P, Spainhower KB, Kombak FE, Sanchez-Rivera FJ, Jaspers JE, Zavitsanou AM, Maddalo D, ... ... Papagiannakopoulos T, et al. Rlf-Mycl gene fusion drives tumorigenesis and metastasis in a mouse model of small cell lung cancer. Cancer Discovery. PMID 34344693 DOI: 10.1158/2159-8290.CD-21-0441  0.325
2021 Kerk SA, Papagiannakopoulos T, Shah YM, Lyssiotis CA. Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment. Nature Reviews. Cancer. PMID 34244683 DOI: 10.1038/s41568-021-00375-9  0.318
2021 Kerk SA, Papagiannakopoulos T, Shah YM, Lyssiotis CA. Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment. Nature Reviews. Cancer. PMID 34244683 DOI: 10.1038/s41568-021-00375-9  0.318
2021 Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, ... ... Papagiannakopoulos T, et al. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514. PMID 34142094 DOI: 10.1038/s43018-021-00208-6  0.704
2021 Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, ... ... Papagiannakopoulos TY, et al. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. Genes & Development. PMID 33446568 DOI: 10.1101/gad.344184.120  0.762
2020 Tsay JJ, Wu BG, Sulaiman I, Gershner K, Schluger R, Li Y, Yie TA, Meyn P, Olsen E, Perez L, Franca B, Carpenito J, Iizumi T, El-Ashmawy M, Badri M, ... ... Papagiannakopoulos T, et al. Lower airway dysbiosis affects lung cancer progression. Cancer Discovery. PMID 33177060 DOI: 10.1158/2159-8290.CD-20-0263  0.591
2020 Ciampricotti M, Karakousi T, Villalonga AQ, Allaj V, Ventura A, Sen T, Poirier J, Papagiannakopoulos T, Rudin CM. Abstract 420: Rlf-Mycl1 gene fusion as a novel oncogenic driver in a mouse model of small cell lung cancer Cancer Research. 80: 420-420. DOI: 10.1158/1538-7445.Am2020-420  0.323
2019 LeBoeuf SE, Wu WL, Karakousi TR, Karadal B, Jackson SR, Davidson SM, Wong KK, Koralov SB, Sayin VI, Papagiannakopoulos T. Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids. Cell Metabolism. PMID 31813821 DOI: 10.1016/J.Cmet.2019.11.012  0.325
2019 Li F, Huang Q, Luster TA, Hu H, Zhang H, Ng WL, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling CM, Bagdatlioglu E, ... ... Papagiannakopoulos T, et al. In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma. Cancer Discovery. PMID 31744829 DOI: 10.1158/2159-8290.Cd-19-0780  0.751
2019 Sayin VI, LeBoeuf SE, Papagiannakopoulos T. Targeting Metabolic Bottlenecks in Lung Cancer. Trends in Cancer. 5: 457-459. PMID 31421901 DOI: 10.1016/J.Trecan.2019.06.001  0.323
2019 Lignitto L, LeBoeuf SE, Homer H, Jiang S, Askenazi M, Karakousi TR, Pass HI, Bhutkar AJ, Tsirigos A, Ueberheide B, Sayin VI, Papagiannakopoulos T, Pagano M. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. PMID 31257023 DOI: 10.1016/J.Cell.2019.06.003  0.689
2018 Snuderl M, Kannan K, Pfaff E, Wang S, Stafford JM, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton SL, Zagzag D, Chiriboga L, Gardner SL, ... ... Papagiannakopoulos TY, et al. Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nature Communications. 9: 2868. PMID 30030436 DOI: 10.1038/S41467-018-05029-3  0.613
2018 Garcia-Bermudez J, Baudrier L, La K, Zhu XG, Fidelin J, Sviderskiy VO, Papagiannakopoulos T, Molina H, Snuderl M, Lewis CA, Possemato RL, Birsoy K. Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours. Nature Cell Biology. PMID 29941933 DOI: 10.1038/S41556-018-0118-Z  0.305
2018 Romero R, Sayin VI, Shawn DM, Bauer M, Singh SX, LeBoeuf S, Karakousi TR, Ellis DC, Bhutkar A, Sanchez-Rivera F, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, ... ... Papagiannakopoulos T, et al. Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-A43  0.679
2018 Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato RL. Abstract NG02: NFS1 undergoes positive selection in lung tumors and protects cells from ferroptosis Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ng02  0.333
2018 Snuderl M, Kannan K, Pfaff E, Wang S, Stafford J, Serrano J, Heguy A, Ray K, Faustin A, Aminova O, Dolgalev I, Stapleton S, Zagzag D, Chiriboga L, Gardner S, ... ... Papagiannakopoulos T, et al. EMBR-02. RECURRENT HOMOZYGOUS DELETION OF DROSHA AND MICRODUPLICATION OF PDE4DIP CONTAINING THE ANCESTRAL DUF1220 DOMAIN IN PINEOBLASTOMA Neuro-Oncology. 20: i69-i69. DOI: 10.1093/Neuonc/Noy059.187  0.555
2017 Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, ... ... Papagiannakopoulos T, et al. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nature Medicine. PMID 28967920 DOI: 10.1038/Nm.4407  0.674
2016 Ashouri A, Sayin VI, Van den Eynden J, Singh SX, Papagiannakopoulos T, Larsson E. Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. Nature Communications. 7: 13197. PMID 28959951 DOI: 10.1038/Ncomms13197  0.31
2016 Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, et al. Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers. Science (New York, N.Y.). 353: 1161-5. PMID 27609895 DOI: 10.1126/Science.Aaf5171  0.343
2016 Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, et al. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer. Cell Metabolism. PMID 26853747 DOI: 10.1016/J.Cmet.2016.01.007  0.308
2016 Mayers JR, Torrence ME, Davidson SM, Papagiannakopoulos T, Lau AN, Jacks T, Heiden MGV. Abstract PR11: Tissue-of-origin dictates the metabolic fate of branched chain amino acids in mutant Kras-driven cancers Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-Pr11  0.336
2014 Sánchez-Rivera FJ, Papagiannakopoulos T, Romero R, Tammela T, Bauer MR, Bhutkar A, Joshi NS, Subbaraj L, Bronson RT, Xue W, Jacks T. Rapid modelling of cooperating genetic events in cancer through somatic genome editing. Nature. 516: 428-31. PMID 25337879 DOI: 10.1038/Nature13906  0.332
2014 McFadden DG, Papagiannakopoulos T, Taylor-Weiner A, Stewart C, Carter SL, Cibulskis K, Bhutkar A, McKenna A, Dooley A, Vernon A, Sougnez C, Malstrom S, Heimann M, Park J, Chen F, et al. Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing. Cell. 156: 1298-311. PMID 24630729 DOI: 10.1016/J.Cell.2014.02.031  0.325
2014 Carter SL, Brastianos PK, McFadden DG, Papagiannakopoulos T, Taylor-Weiner A, Cibulskis K, Jacks T, Hahn W, Getz G. Abstract 3992: Modes of metastasis evolution in human and murine cancer revealed by whole exome sequencing Cancer Research. 74: 3992-3992. DOI: 10.1158/1538-7445.Am2014-3992  0.36
2013 McFadden DG, Papagiannakopoulos T, Cibulskis K, Stewart C, Carter S, Taylor-Weiner A, Bhutkar A, Sougnez C, Dooley A, Shefler E, Lander E, Gabriel S, Getz G, Jacks T. Abstract 1084: Comprehensive genomic analysis of murine small cell lung carcinoma uncovers recurrent Pten alterations that drive tumor progression and alter tumor genome evolution. Cancer Research. 73: 1084-1084. DOI: 10.1158/1538-7445.Am2013-1084  0.341
2012 Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Liu C, Zong H, Rowitch DH, Barres BA, Verma IM, Kosik KS. Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene. 31: 1884-95. PMID 21874051 DOI: 10.1038/Onc.2011.380  0.482
2009 Papagiannakopoulos T, Kosik KS. MicroRNA-124: micromanager of neurogenesis. Cell Stem Cell. 4: 375-6. PMID 19427286 DOI: 10.1016/J.Stem.2009.04.007  0.395
2009 Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 137: 647-58. PMID 19409607 DOI: 10.1016/J.Cell.2009.02.038  0.428
2009 Carrettiero DC, Hernandez I, Neveu P, Papagiannakopoulos T, Kosik KS. The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2151-61. PMID 19228967 DOI: 10.1523/Jneurosci.4660-08.2009  0.384
2008 Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Research. 68: 8164-72. PMID 18829576 DOI: 10.1158/0008-5472.Can-08-1305  0.492
2008 Papagiannakopoulos T, Kosik KS. MicroRNAs: regulators of oncogenesis and stemness. Bmc Medicine. 6: 15. PMID 18577221 DOI: 10.1186/1741-7015-6-15  0.491
2007 Liu T, Papagiannakopoulos T, Puskar K, Qi S, Santiago F, Clay W, Lao K, Lee Y, Nelson SF, Kornblum HI, Doyle F, Petzold L, Shraiman B, Kosik KS. Detection of a microRNA signal in an in vivo expression set of mRNAs. Plos One. 2: e804. PMID 17726534 DOI: 10.1371/Journal.Pone.0000804  0.447
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