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Ricardo Benjamin Maccioni, PhD, University of Chile 1975 - Publications

Affiliations: 
Biology University of Chile, Santiago, Región Metropolitana, Chile 
Area:
neuroscience
Website:
http://www.biologia-ciencias-uchile.cl/wp/?page_id=835
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Year Citation  Score
2023 Andrade V, Wong-Guerra M, Cortés N, Pastor G, González A, Calfío C, Guzmán-Martínez L, Navarrete LP, Ramos-Escobar N, Morales I, Santander R, Andrades-Lagos J, Bacho M, Rojo LE, Maccioni RB. Scaling the Andean Shilajit: A Novel Neuroprotective Agent for Alzheimer's Disease. Pharmaceuticals (Basel, Switzerland). 16. PMID 37513872 DOI: 10.3390/ph16070960  0.78
2023 Wong-Guerra M, Calfio C, Maccioni RB, Rojo LE. Revisiting the neuroinflammation hypothesis in Alzheimer's disease: a focus on the druggability of current targets. Frontiers in Pharmacology. 14: 1161850. PMID 37361208 DOI: 10.3389/fphar.2023.1161850  0.688
2022 Mishra SK, Balendra V, Esposto J, Obaid AA, Maccioni RB, Jha NK, Perry G, Moustafa M, Al-Shehri M, Singh MP, Khan AA, Vamanu E, Singh SK. Therapeutic Antiaging Strategies. Biomedicines. 10. PMID 36289777 DOI: 10.3390/biomedicines10102515  0.357
2022 González A, Singh SK, Churruca M, Maccioni RB. Alzheimer's Disease and Tau Self-Assembly: In the Search of the Missing Link. International Journal of Molecular Sciences. 23. PMID 35457009 DOI: 10.3390/ijms23084192  0.397
2022 Maccioni RB, Calfío C, González A, Lüttges V. Novel Nutraceutical Compounds in Alzheimer Prevention. Biomolecules. 12. PMID 35204750 DOI: 10.3390/biom12020249  0.324
2021 Guzman-Martinez L, Farías GA, Tapia JP, Sánchez MP, Fuentes P, Gloger S, Maccioni RB. Interventional Study to Evaluate the Clinical Effects and Safety of the Nutraceutical Compound BrainUp-10® in a Cohort of Patients with Alzheimer's Disease: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Trial. Journal of Alzheimer's Disease : Jad. 81: 1231-1241. PMID 33935080 DOI: 10.3233/JAD-201501  0.796
2021 Guzman-Martinez L, Calfío C, Farias GA, Vilches C, Prieto R, Maccioni RB. New Frontiers in the Prevention, Diagnosis, and Treatment of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33523002 DOI: 10.3233/JAD-201059  0.736
2020 González A, Guzmán-Martínez L, Maccioni RB. Plasma Tau Variants Detected by a Novel Anti-Tau Monoclonal Antibody: A Potential Biomarker for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32741827 DOI: 10.3233/JAD-200386  0.471
2020 Calfio C, Gonzalez A, Singh SK, Rojo LE, Maccioni RB. The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32651325 DOI: 10.3233/JAD-200443  0.674
2020 Maccioni RB, Navarrete LP, González A, González-Canacer A, Guzmán-Martínez L, Cortés N. Inflammation: A Major Target for Compounds to Control Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32597798 DOI: 10.3233/JAD-191014  0.433
2020 Andrade V, Cortés N, Pastor G, Gonzalez A, Ramos-Escobar N, Pastene E, Rojo LE, Maccioni RB. N-Acetyl Cysteine and Catechin-Derived Polyphenols: A Path Toward Multi-Target Compounds Against Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32390631 DOI: 10.3233/JAD-200067  0.69
2019 Guzman-Martinez L, Maccioni RB, Andrade V, Navarrete LP, Pastor MG, Ramos-Escobar N. Neuroinflammation as a Common Feature of Neurodegenerative Disorders. Frontiers in Pharmacology. 10: 1008. PMID 31572186 DOI: 10.3389/fphar.2019.01008  0.463
2019 Guzman-Martinez L, Maccioni RB, Farías GA, Fuentes P, Navarrete LP. Biomarkers for Alzheimer´s disease. Current Alzheimer Research. PMID 31099321 DOI: 10.2174/1567205016666190517121140  0.818
2019 Cortés N, Guzmán-Martínez L, Andrade V, González A, Maccioni RB. CDK5: A Unique CDK and Its Multiple Roles in the Nervous System. Journal of Alzheimer's Disease : Jad. PMID 30856110 DOI: 10.3233/JAD-180792  0.41
2019 Guzmán-Martínez L, Tapia JP, Farías GA, González A, Estrella M, Maccioni RB. The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population. Journal of Alzheimer's Disease : Jad. PMID 30775977 DOI: 10.3233/JAD-180637  0.774
2018 Maccioni RB, González A, Andrade V, Cortés N, Tapia JP, Guzmán-Martínez L. Alzheimer´s Disease in the Perspective of Neuroimmunology. The Open Neurology Journal. 12: 50-56. PMID 30069256 DOI: 10.2174/1874205X01812010050  0.505
2018 Maccioni RB, Tapia JP, Guzman-Martinez L. Pathway to Tau Modifications and the Origins of Alzheimer's Disease. Archives of Medical Research. PMID 29861329 DOI: 10.1016/j.arcmed.2018.05.002  0.483
2018 Cortés N, Andrade V, Maccioni RB. Behavioral and Neuropsychiatric Disorders in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29710717 DOI: 10.3233/JAD-180005  0.458
2018 Cortés N, Andrade V, Guzmán-Martínez L, Estrella M, Maccioni RB. Neuroimmune Tau Mechanisms: Their Role in the Progression of Neuronal Degeneration. International Journal of Molecular Sciences. 19. PMID 29570615 DOI: 10.3390/ijms19040956  0.512
2018 Andrade V, Guzman-Martinez L, Cortes N, Gonzalez A, Farias G, Maccioni RB. The Emergency of Nutraceutical Compounds in the Preventive Medicine Scenario. Potential for Treatment of Alzheimer's Disease and Other Chronic Disorders Journal of Alzheimer’S Disease & Parkinsonism. 8. DOI: 10.4172/2161-0460.1000456  0.72
2017 Morales I, Cerda-Troncoso C, Andrade V, Maccioni RB. The Natural Product Curcumin as a Potential Coadjuvant in Alzheimer's Treatment. Journal of Alzheimer's Disease : Jad. PMID 28854504 DOI: 10.3233/Jad-170354  0.727
2016 Slachevsky A, Guzmán-Martínez L, Delgado C, Reyes P, Farías GA, Muñoz-Neira C, Bravo E, Farías M, Flores P, Garrido C, Becker JT, López OL, Maccioni RB. Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27911301 DOI: 10.3233/Jad-160652  0.785
2015 Morales I, Henriquez D, Farias G, Maccioni R. Platelets tau mRNA isoforms in neurodegenerative diseases Journal of the Neurological Sciences. 357: e125. DOI: 10.1016/J.Jns.2015.08.402  0.789
2014 Farías GA, Guzmán-Martínez L, Delgado C, Maccioni RB. Nutraceuticals: a novel concept in prevention and treatment of Alzheimer's disease and related disorders. Journal of Alzheimer's Disease : Jad. 42: 357-67. PMID 24927706 DOI: 10.3233/JAD-132741  0.733
2014 Morales I, Guzmán-Martínez L, Cerda-Troncoso C, Farías GA, Maccioni RB. Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches. Frontiers in Cellular Neuroscience. 8: 112. PMID 24795567 DOI: 10.3389/Fncel.2014.00112  0.811
2013 Guzmán-Martinez L, Farías GA, Maccioni RB. Tau oligomers as potential targets for Alzheimer's diagnosis and novel drugs. Frontiers in Neurology. 4: 167. PMID 24191153 DOI: 10.3389/fneur.2013.00167  0.79
2013 Morales I, Jiménez JM, Mancilla M, Maccioni RB. Tau oligomers and fibrils induce activation of microglial cells. Journal of Alzheimer's Disease : Jad. 37: 849-56. PMID 23948931 DOI: 10.3233/Jad-131843  0.725
2012 Maccioni RB. Introductory remarks. Molecular, biological and clinical aspects of Alzheimer's disease. Archives of Medical Research. 43: 593-4. PMID 23149157 DOI: 10.1016/j.arcmed.2012.11.001  0.385
2012 Guzmán-Martínez L, Farías GA, Maccioni RB. Emerging noninvasive biomarkers for early detection of Alzheimer's disease. Archives of Medical Research. 43: 663-6. PMID 23142260 DOI: 10.1016/j.arcmed.2012.10.013  0.421
2012 Carrasco-Gallardo C, Farías GA, Fuentes P, Crespo F, Maccioni RB. Can nutraceuticals prevent Alzheimer's disease? Potential therapeutic role of a formulation containing shilajit and complex B vitamins. Archives of Medical Research. 43: 699-704. PMID 23131823 DOI: 10.1016/J.Arcmed.2012.10.010  0.731
2012 Farías G, Pérez P, Slachevsky A, Maccioni RB. Platelet tau pattern correlates with cognitive status in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 65-9. PMID 22495344 DOI: 10.3233/Jad-2012-120304  0.443
2012 Carrasco-Gallardo C, Guzmán L, Maccioni RB. Shilajit: a natural phytocomplex with potential procognitive activity. International Journal of Alzheimer's Disease. 2012: 674142. PMID 22482077 DOI: 10.1155/2012/674142  0.347
2012 Navarrete LP, Guzmán L, San Martín A, Astudillo-Saavedra L, Maccioni RB. Molecules of the quinoline family block tau self-aggregation: implications toward a therapeutic approach for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 29: 79-88. PMID 22232002 DOI: 10.3233/JAD-2011-110995  0.513
2012 Mendoza-Naranjo A, Contreras-Vallejos E, Henriquez DR, Otth C, Bamburg JR, Maccioni RB, Gonzalez-Billault C. Fibrillar amyloid-β1-42 modifies actin organization affecting the cofilin phosphorylation state: a role for Rac1/cdc42 effector proteins and the slingshot phosphatase. Journal of Alzheimer's Disease : Jad. 29: 63-77. PMID 22204905 DOI: 10.3233/Jad-2012-101575  0.702
2011 Maccioni RB. Tau protein in Alzheimer’s disease. Current Alzheimer Research. 8: 607. PMID 21827396 DOI: 10.2174/156720511796717159  0.322
2011 Cornejo A, Jiménez JM, Caballero L, Melo F, Maccioni RB. Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 143-53. PMID 21785188 DOI: 10.3233/JAD-2011-110623  0.493
2011 Farías G, Cornejo A, Jiménez J, Guzmán L, Maccioni RB. Mechanisms of tau self-aggregation and neurotoxicity. Current Alzheimer Research. 8: 608-14. PMID 21605046 DOI: 10.2174/156720511796717258  0.534
2011 Rojo LE, Gaspar PA, Maccioni RB. Molecular targets in the rational design of AD specific PET tracers: tau or amyloid aggregates? Current Alzheimer Research. 8: 652-8. PMID 21605040 DOI: 10.2174/156720511796717203  0.709
2011 Navarrete LP, Pérez P, Morales I, Maccioni RB. Novel drugs affecting tau behavior in the treatment of Alzheimer's disease and tauopathies. Current Alzheimer Research. 8: 678-85. PMID 21605038 DOI: 10.2174/156720511796717122  0.743
2011 Neumann K, Farías G, Slachevsky A, Perez P, Maccioni RB. Human platelets tau: a potential peripheral marker for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 103-9. PMID 21368381 DOI: 10.3233/Jad-2011-101641  0.481
2010 Zambrano A, Otth C, Maccioni RB, Concha II. IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Current Alzheimer Research. 7: 615-24. PMID 20964623 DOI: 10.2174/156720510793499011  0.352
2010 Maccioni RB, Farías G, Morales I, Navarrete L. The revitalized tau hypothesis on Alzheimer's disease. Archives of Medical Research. 41: 226-31. PMID 20682182 DOI: 10.1016/J.Arcmed.2010.03.007  0.724
2010 Morales I, Farías G, Maccioni RB. Neuroimmunomodulation in the pathogenesis of Alzheimer's disease. Neuroimmunomodulation. 17: 202-4. PMID 20134203 DOI: 10.1159/000258724  0.718
2010 Rojo LE, Alzate-Morales J, Saavedra IN, Davies P, Maccioni RB. Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 573-89. PMID 20110603 DOI: 10.3233/JAD-2010-1262  0.676
2010 Farias G, Neurmann K, Slachevsky A, Perez P, Maccioni R. Tau in platelets as a potential biological marker for Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1696  0.759
2009 Utreras E, Maccioni R, González-Billault C. Cyclin-dependent kinase 5 activator p35 over-expression and amyloid beta synergism increase apoptosis in cultured neuronal cells Neuroscience. 161: 978-987. PMID 19362124 DOI: 10.1016/J.Neuroscience.2009.04.002  0.708
2009 Maccioni RB, Rojo LE, Fernández JA, Kuljis RO. The role of neuroimmunomodulation in Alzheimer's disease. Annals of the New York Academy of Sciences. 1153: 240-6. PMID 19236346 DOI: 10.1111/j.1749-6632.2008.03972.x  0.807
2009 Hernandez P, Lee G, Sjoberg M, Maccioni RB. Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): involvement of lipid rafts. Journal of Alzheimer's Disease : Jad. 16: 149-56. PMID 19158430 DOI: 10.3233/Jad-2009-0933  0.818
2009 Maccioni RB, Farias GA, Rojo LE, Sekler MA, Kuljis RO. What have we learned from the tau hypothesis? Current Hypotheses and Research Milestones in Alzheimer's Disease. 49-62. DOI: 10.1007/978-0-387-87995-6_5  0.768
2009 Rojo LE, Fernández J, Jiménez J, Maccioni AA, Sekler A, Kuljis RO, Maccioni RB. Central nervous system inflammation and cholesterol metabolism alterations in the pathogenesis of Alzheimer's disease and their diagnostic and therapeutic implications Current Hypotheses and Research Milestones in Alzheimer's Disease. 125-137. DOI: 10.1007/978-0-387-87995-6_11  0.795
2008 Sekler A, Jiménez JM, Rojo L, Pastene E, Fuentes P, Slachevsky A, Maccioni RB. Cognitive impairment and Alzheimer's disease: Links with oxidative stress and cholesterol metabolism. Neuropsychiatric Disease and Treatment. 4: 715-22. PMID 19043515 DOI: 10.2147/Ndt.S3268  0.781
2008 Neumann KF, Rojo L, Navarrete LP, Farías G, Reyes P, Maccioni RB. Insulin resistance and Alzheimer's disease: molecular links & clinical implications. Current Alzheimer Research. 5: 438-47. PMID 18855585 DOI: 10.2174/156720508785908919  0.63
2008 Fernández JA, Rojo L, Kuljis RO, Maccioni RB. The damage signals hypothesis of Alzheimer's disease pathogenesis. Journal of Alzheimer's Disease : Jad. 14: 329-33. PMID 18599959 DOI: 10.3233/Jad-2008-14307  0.806
2008 Lavados M, Guillón M, Mujica MC, Rojo LE, Fuentes P, Maccioni RB. Mild cognitive impairment and Alzheimer patients display different levels of redox-active CSF iron. Journal of Alzheimer's Disease : Jad. 13: 225-32. PMID 18376063 DOI: 10.3233/Jad-2008-13211  0.768
2008 Utreras E, Jiménez-Mateos EM, Contreras-Vallejos E, Tortosa E, Pérez M, Rojas S, Saragoni L, Maccioni RB, Avila J, González-Billault C. Microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination. Developmental Neuroscience. 30: 200-10. PMID 18075266 DOI: 10.1159/000109863  0.653
2008 Rojo LE, Fernández JA, Maccioni AA, Jimenez JM, Maccioni RB. Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease. Archives of Medical Research. 39: 1-16. PMID 18067990 DOI: 10.1016/j.arcmed.2007.10.001  0.699
2007 Zambrano A, Otth C, Mujica L, Concha II, Maccioni RB. Interleukin-3 prevents neuronal death induced by amyloid peptide. Bmc Neuroscience. 8: 82. PMID 17915029 DOI: 10.1186/1471-2202-8-82  0.354
2007 Mendoza-Naranjo A, Gonzalez-Billault C, Maccioni RB. Abeta1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases. Journal of Cell Science. 120: 279-88. PMID 17200137 DOI: 10.1242/Jcs.03323  0.704
2007 Orellana DI, Quintanilla RA, Maccioni RB. Neuroprotective effect of TNFalpha against the beta-amyloid neurotoxicity mediated by CDK5 kinase. Biochimica Et Biophysica Acta. 1773: 254-63. PMID 17150266 DOI: 10.1016/j.bbamcr.2006.10.010  0.822
2007 Muñoz JP, Huichalaf CH, Orellana D, Maccioni RB. cdk5 modulates beta- and delta-catenin/Pin1 interactions in neuronal cells. Journal of Cellular Biochemistry. 100: 738-49. PMID 17009320 DOI: 10.1002/jcb.21041  0.772
2006 Rojo L, Sjöberg MK, Hernández P, Zambrano C, Maccioni RB. Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. Journal of Biomedicine & Biotechnology. 2006: 73976. PMID 17047312 DOI: 10.1155/Jbb/2006/73976  0.797
2006 Sáez ET, Pehar M, Vargas MR, Barbeito L, Maccioni RB. Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. Journal of Neuroscience Research. 84: 1098-106. PMID 16862561 DOI: 10.1002/jnr.20996  0.696
2006 Sjöberg MK, Shestakova E, Mansuroglu Z, Maccioni RB, Bonnefoy E. Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization. Journal of Cell Science. 119: 2025-34. PMID 16638814 DOI: 10.1242/jcs.02907  0.352
2006 Maccioni RB, Lavados M, Guillón M, Mujica C, Bosch R, Farías G, Fuentes P. Anomalously phosphorylated tau and Abeta fragments in the CSF correlates with cognitive impairment in MCI subjects. Neurobiology of Aging. 27: 237-44. PMID 16399209 DOI: 10.1016/J.Neurobiolaging.2005.01.011  0.763
2005 Orellana DI, Quintanilla RA, Gonzalez-Billault C, Maccioni RB. Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons. Neurotoxicity Research. 8: 295-304. PMID 16371324 DOI: 10.1007/BF03033983  0.782
2005 Lavados M, Farías G, Rothhammer F, Guillon M, Mujica MC, Maccioni C, Maccioni RB. ApoE alleles and tau markers in patients with different levels of cognitive impairment. Archives of Medical Research. 36: 474-9. PMID 16099324 DOI: 10.1016/j.arcmed.2005.03.036  0.436
2004 Maccioni RB, Lavados M, Maccioni CB, Mendoza-Naranjo A. Biological markers of Alzheimer's disease and mild cognitive impairment. Current Alzheimer Research. 1: 307-14. PMID 15975059 DOI: 10.2174/1567205043332018  0.513
2004 Saez TE, Pehar M, Vargas M, Barbeito L, Maccioni RB. Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo (Athens, Greece). 18: 275-80. PMID 15341183  0.347
2004 Zambrano CA, Egaña JT, Núñez MT, Maccioni RB, González-Billault C. Oxidative stress promotes tau dephosphorylation in neuronal cells: the roles of cdk5 and PP1. Free Radical Biology & Medicine. 36: 1393-402. PMID 15135175 DOI: 10.1016/J.Freeradbiomed.2004.03.007  0.688
2004 Quintanilla RA, Orellana DI, González-Billault C, Maccioni RB. Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Experimental Cell Research. 295: 245-57. PMID 15051507 DOI: 10.1016/J.Yexcr.2004.01.002  0.805
2004 Zapata-Torres G, Opazo F, Salgado C, Muñoz JP, Krautwurst H, Mascayano C, Sepúlveda-Boza S, Maccioni RB, Cassels BK. Effects of natural flavones and flavonols on the kinase activity of Cdk5. Journal of Natural Products. 67: 416-20. PMID 15043421 DOI: 10.1021/np034011s  0.363
2004 Liu Q, Smith MA, Siedlak SL, Harris PL, Maccioni RB, Sayre LM, Perry G. P3-275 Phosphorylation dependent control of oxidative modification in Alzheimer disease Neurobiology of Aging. 25: S432-S433. DOI: 10.1016/S0197-4580(04)81425-8  0.506
2003 Otth C, Mendoza-Naranjo A, Mujica L, Zambrano A, Concha II, Maccioni RB. Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease. Neuroreport. 14: 2403-9. PMID 14663200 DOI: 10.1097/01.wnr.0000099988.54721.3c  0.412
2003 Muñoz JP, Sánchez JR, Maccioni RB. Regulation of p27 in the process of neuroblastoma N2A differentiation. Journal of Cellular Biochemistry. 89: 539-49. PMID 12761887 DOI: 10.1002/jcb.10525  0.312
2003 Egaña JT, Zambrano C, Nuñez MT, Gonzalez-Billault C, Maccioni RB. Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 215-23. PMID 12572681 DOI: 10.1023/A:1020727218493  0.682
2002 Otth C, Concha II, Arendt T, Stieler J, Schliebs R, González-Billault C, Maccioni RB. AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576. Journal of Alzheimer's Disease : Jad. 4: 417-30. PMID 12446973 DOI: 10.3233/Jad-2002-4508  0.651
2002 Farias GA, Muñoz JP, Garrido J, Maccioni RB. Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies. Journal of Cellular Biochemistry. 85: 315-24. PMID 11948687 DOI: 10.1002/jcb.10133  0.399
2001 Cambiazo V, González M, Maccioni RB. Expression pattern of DMAP-85 during Drosophila embryonic development. Mechanisms of Development. 108: 197-201. PMID 11578875 DOI: 10.1016/S0925-4773(01)00481-6  0.651
2001 Maccioni RB, Muñoz JP, Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Archives of Medical Research. 32: 367-81. PMID 11578751 DOI: 10.1016/S0188-4409(01)00316-2  0.451
2001 Alvarez A, Muñoz JP, Maccioni RB. A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons. Experimental Cell Research. 264: 266-74. PMID 11262183 DOI: 10.1006/excr.2001.5152  0.355
2001 Maccioni RB, Otth C, Concha II, Muñoz JP. The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. European Journal of Biochemistry / Febs. 268: 1518-27. PMID 11248668 DOI: 10.1046/j.1432-1327.2001.02024.x  0.443
2000 Muñoz JP, Alvarez A, Maccioni RB. Increase in the expression of the neuronal cyclin-dependent protein kinase cdk-5 during differentiation of N2A neuroblastoma cells. Neuroreport. 11: 2733-8. PMID 10976953 DOI: 10.1097/00001756-200008210-00025  0.415
2000 Cross DC, Muñoz JP, Hernández P, Maccioni RB. Nuclear and cytoplasmic tau proteins from human nonneuronal cells share common structural and functional features with brain tau. Journal of Cellular Biochemistry. 78: 305-17. PMID 10842324 DOI: 10.1002/(Sici)1097-4644(20000801)78:2<305::Aid-Jcb12>3.0.Co;2-W  0.746
2000 Saragoni L, Hernández P, Maccioni RB. Differential association of tau with subsets of microtubules containing posttranslationally-modified tubulin variants in neuroblastoma cells. Neurochemical Research. 25: 59-70. PMID 10685605 DOI: 10.1023/A:1007587315630  0.737
1999 Alvarez A, Toro R, Cáceres A, Maccioni RB. Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death. Febs Letters. 459: 421-6. PMID 10526177 DOI: 10.1016/S0014-5793(99)01279-X  0.369
1999 Cambiazo V, González M, Isamit C, Maccioni RB. The beta-isoform of heat shock protein hsp-90 is structurally related with human microtubule-interacting protein Mip-90. Febs Letters. 457: 343-7. PMID 10471805 DOI: 10.1016/S0014-5793(99)01070-4  0.655
1999 Ramírez G, Alvarez A, Garcia-Abreu J, Gomes FC, Moura Neto V, Maccioni RB. Regulatory roles of microtubule-associated proteins in neuronal morphogenesis. Involvement of the extracellular matrix. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 32: 611-8. PMID 10412573 DOI: 10.1590/S0100-879X1999000500015  0.403
1998 González C, Farías G, Maccioni RB. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules. Cellular and Molecular Biology (Noisy-Le-Grand, France). 44: 1117-27. PMID 9846894  0.411
1998 González M, Cambiazo V, Maccioni RB. The interaction of Mip-90 with microtubules and actin filaments in human fibroblasts. Experimental Cell Research. 239: 243-53. PMID 9521842 DOI: 10.1006/excr.1997.3875  0.669
1998 Capote C, Maccioni RB. The association of tau-like proteins with vimentin filaments in cultured cells. Experimental Cell Research. 239: 202-13. PMID 9521838 DOI: 10.1006/Excr.1997.3902  0.78
1997 Farías G, González-Billault C, Maccioni RB. Immunological characterization of epitopes on tau of Alzheimer's type and chemically modified tau. Molecular and Cellular Biochemistry. 168: 59-66. PMID 9062894 DOI: 10.1023/A:1006838626730  0.412
1996 Cross D, Tapia L, Garrido J, Maccioni RB. Tau-like proteins associated with centrosomes in cultured cells. Experimental Cell Research. 229: 378-87. PMID 8986621 DOI: 10.1006/excr.1996.0383  0.472
1996 Henríquez JP, Cambiazo V, Maccioni RB. Tubulin domains for the interaction of microtubule associated protein DMAP-85 from Drosophila melanogaster. Molecular and Cellular Biochemistry. 158: 149-59. PMID 8817477 DOI: 10.1007/Bf00225841  0.674
1995 Henríquez JP, Cross D, Vial C, Maccioni RB. Subpopulations of tau interact with microtubules and actin filaments in various cell types. Cell Biochemistry and Function. 13: 239-50. PMID 10232926 DOI: 10.1002/cbf.290130404  0.453
1995 Maccioni RB, Tapia L, Cambiazo V. Functional organization of tau proteins during neuronal differentiation and development. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 28: 827-41. PMID 8555984  0.378
1995 Cambiazo V, González M, Maccioni RB. DMAP-85: a tau-like protein from Drosophila melanogaster larvae. Journal of Neurochemistry. 64: 1288-97. PMID 7861162 DOI: 10.1046/J.1471-4159.1995.64031288.X  0.688
1995 Santibañez JF, Maccioni RB, Martínez J. The secretion of urokinase-like plasminogen activator is inhibited by microtubule-interacting drugs. Cell Biochemistry and Function. 13: 217-25. PMID 7554101 DOI: 10.1002/cbf.290130313  0.34
1995 Vial C, Armas-Portela R, Avila J, González M, Maccioni RB. A 205 kDa protein from non-neuronal cells in culture contains tubulin binding epitopes. Molecular and Cellular Biochemistry. 144: 109-116. PMID 7542740 DOI: 10.1007/Bf00944389  0.386
1995 Maccioni RB, Cambiazo V. Role of microtubule-associated proteins in the control of microtubule assembly. Physiological Reviews. 75: 835-64. PMID 7480164 DOI: 10.1152/PHYSREV.1995.75.4.835  0.646
1995 Farias G, Gonzalez M, Maccioni RB. Tubulin and microtubule-associated protein pools in unfertilized and fertilized eggs of the trout Oncorhynchus mykiss Journal of Experimental Zoology. 271: 253-263. DOI: 10.1002/Jez.1402710403  0.318
1994 Cross D, Farías G, Domínguez J, Avila J, Maccioni RB. Carboxyl terminal sequences of beta-tubulin involved in the interaction of HMW-MAPs. Studies using site-specific antibodies. Molecular and Cellular Biochemistry. 132: 81-90. PMID 8078512 DOI: 10.1007/BF00925677  0.307
1994 Guzman L, Bustos R, Maccioni RB. Purification and characterization of the high molecule weight microtubule associated proteins from neonatal rat brain. Molecular and Cellular Biochemistry. 131: 105-13. PMID 8035775 DOI: 10.1007/BF00925946  0.309
1993 Moraga DM, Nuñez P, Garrido J, Maccioni RB. A tau fragment containing a repetitive sequence induces bundling of actin filaments. Journal of Neurochemistry. 61: 979-86. PMID 8360695 DOI: 10.1111/J.1471-4159.1993.Tb03611.X  0.406
1993 Farías GA, Vial C, Maccioni RB. Functional domains on chemically modified tau protein. Cellular and Molecular Neurobiology. 13: 173-82. PMID 8348591 DOI: 10.1007/BF00735373  0.472
1993 Cross D, Vial C, Maccioni RB. A tau-like protein interacts with stress fibers and microtubules in human and rodent cultured cell lines. Journal of Cell Science. 105: 51-60. PMID 7689576  0.318
1992 Moraga D, Rivas-Berrios A, Farías G, Wallin M, Maccioni RB. Estramustine-phosphate binds to a tubulin binding domain on microtubule-associated proteins MAP-2 and tau. Biochimica Et Biophysica Acta. 1121: 97-103. PMID 1599956 DOI: 10.1016/0167-4838(92)90342-B  0.792
1992 Farías GA, Vial C, Maccioni RB. Specific macromolecular interactions between tau and the microtubule system. Molecular and Cellular Biochemistry. 112: 81-8. PMID 1513337 DOI: 10.1007/BF00229646  0.426
1992 Martínez J, Santibáñez JF, Vial C, Maccioni RB. The antineoplastic agent estramustine and the derivative estramustine-phosphate inhibit secretion of interleukin-3 in leukemic cells. Possible roles of MAPs. Molecular and Cellular Biochemistry. 117: 165-73. PMID 1488050 DOI: 10.1007/BF00230756  0.377
1990 Padilla R, Maccioni RB, Avila J. Calmodulin binds to a tubulin binding site of the microtubule-associated protein tau. Molecular and Cellular Biochemistry. 97: 35-41. PMID 2123288 DOI: 10.1007/BF00231699  0.383
1989 Vera JC, Rivas CI, Maccioni RB. Biochemical dissection of the role of the one-kilodalton carboxyl-terminal moiety of tubulin in its assembly into microtubules. Biochemistry. 28: 333-9. PMID 2706257 DOI: 10.1021/Bi00427A045  0.572
1989 Maccioni RB, Vera JC, Dominguez J, Avila J. A discrete repeated sequence defines a tubulin binding domain on microtubule-associated protein tau. Archives of Biochemistry and Biophysics. 275: 568-79. PMID 2512858 DOI: 10.1016/0003-9861(89)90403-7  0.618
1988 Rivas CI, Vera JC, Maccioni RB. Anti-idiotypic antibodies that react with microtubule-associated proteins are present in the sera of rabbits immunized with synthetic peptides from tubulin's regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 85: 6092-6. PMID 3413077 DOI: 10.1073/PNAS.85.16.6092  0.576
1988 Vera JC, Rivas CI, Maccioni RB. Heat-stable microtubule protein MAP-1 binds to microtubules and induces microtubule assembly. Febs Letters. 232: 159-62. PMID 3130274 DOI: 10.1016/0014-5793(88)80408-3  0.573
1988 Cann JR, York EJ, Stewart JM, Vera JC, Maccioni RB. Small zone gel chromatography of interacting systems: theoretical and experimental evaluation of elution profiles for kinetically controlled macromolecule-ligand reactions. Analytical Biochemistry. 175: 462-73. PMID 3071186 DOI: 10.1016/0003-2697(88)90570-2  0.521
1988 Vera JC, Rivas CI, Maccioni RB. Antibodies to synthetic peptides from the tubulin regulatory domain interact with tubulin and microtubules. Proceedings of the National Academy of Sciences of the United States of America. 85: 6763-7. PMID 2901104 DOI: 10.1073/PNAS.85.18.6763  0.573
1985 Maccioni RB, Serrano L, Avila J. Structural and functional domains of tubulin Bioessays. 2: 165-169. DOI: 10.1002/BIES.950020407  0.332
1981 Maccioni RB, Vera JC, Slebe JC. Arginyl residues involvement in the microtubule assembly. Archives of Biochemistry and Biophysics. 207: 248-55. PMID 7247402 DOI: 10.1016/0003-9861(81)90031-X  0.559
Low-probability matches (unlikely to be authored by this person)
1991 Cross D, Dominguez J, Maccioni RB, Avila J. MAP-1 and MAP-2 binding sites at the C-terminus of beta-tubulin. Studies with synthetic tubulin peptides. Biochemistry. 30: 4362-6. PMID 2021628 DOI: 10.1021/Bi00231A036  0.299
1998 Depix MS, Martínez J, Santibañez F, Rovirosa J, San Martín A, Maccioni RB. The compound 14-keto-stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells. Molecular and Cellular Biochemistry. 187: 191-9. PMID 9788757 DOI: 10.1023/A:1006879308861  0.294
2003 Maccioni C, Arzola ME, Mujica L, Maccioni R. New paradigms in the study of the pathogenesis of Alzheimer's disease | Nuevos paradigmas en el estudio de la patogénesis de la enfermedad de Alzheimer Revista Chilena De Neuro-Psiquiatria. 41: 33-46.  0.294
2022 González A, Calfío C, Churruca M, Maccioni RB. Glucose metabolism and AD: evidence for a potential diabetes type 3. Alzheimer's Research & Therapy. 14: 56. PMID 35443732 DOI: 10.1186/s13195-022-00996-8  0.287
1995 González M, Cambiazo V, Maccioni RB. Identification of a new microtubule-interacting protein Mip-90. European Journal of Cell Biology. 67: 158-69. PMID 7664757  0.283
2023 González-Madrid A, Calfío C, González A, Lüttges V, Maccioni RB. Toward Prevention and Reduction of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 37807781 DOI: 10.3233/JAD-230454  0.28
1990 Rivas-Berríos A, Hernández MA, Domínguez J, Avila J, Maccioni RB. Common antigenic determinants of the tubulin binding domains of the microtubule-associated proteins MAP-2 and tau. Biochimica Et Biophysica Acta. 1040: 382-90. PMID 1699604 DOI: 10.1016/0167-4838(90)90136-4  0.273
2002 Núñez-Millacura C, Tapia V, Muñoz P, Maccioni RB, Núñez MT. An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells. Journal of Neurochemistry. 82: 240-8. PMID 12124425 DOI: 10.1046/j.1471-4159.2002.00971.x  0.256
1986 Maccioni RB, Seeds NW. Transglutaminase and neuronal differentiation. Molecular and Cellular Biochemistry. 69: 161-8. PMID 2870428 DOI: 10.1007/BF00224763  0.251
1978 Seeds NW, Maccioni RB. Proteins from morphologically differentiated neuroblastoma cells promote tubulin polymerization. The Journal of Cell Biology. 76: 547-55. PMID 10605456  0.245
2015 Farías GA, Nuñez JC, Venegas P, Guzmán-Martínez L, Tapia JP, Maccioni RB. Peripheral biomarkers profile in patients with parkinsonisms Journal of the Neurological Sciences. 357. DOI: 10.1016/J.Jns.2015.08.224  0.244
2022 Jha NK, Chen WC, Kumar S, Dubey R, Tsai LW, Kar R, Jha SK, Gupta PK, Sharma A, Gundamaraju R, Pant K, Mani S, Singh SK, Maccioni RB, Datta T, et al. Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review. Open Biology. 12: 210289. PMID 35291879 DOI: 10.1098/rsob.210289  0.243
2009 Zambrano CA, Marks MJ, Cassels BK, Maccioni RB. In vivo effects of 3-iodocytisine: pharmacological and genetic analysis of hypothermia and evaluation of chronic treatment on nicotinic binding sites. Neuropharmacology. 57: 332-42. PMID 19481555 DOI: 10.1016/j.neuropharm.2009.05.004  0.24
2003 Núñez MT, Núñez-Millacura C, Tapia V, Muñoz P, Mazariegos D, Arredondo M, Muñoz P, Mura C, Maccioni RB. Iron-activated iron uptake: a positive feedback loop mediated by iron regulatory protein 1. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 83-90. PMID 12572667 DOI: 10.1023/A:1020743405347  0.237
1975 Dinamarga ML, Ramírez A, Ballester E, Villar ED, Capdevila J, MacCioni R. DDT-dehydrochlorinase IV.—Further evidence on the lipoprotein nature of the enzyme International Journal of Biochemistry. 6: 405-412. DOI: 10.1016/0020-711X(75)90054-3  0.211
1988 Maccioni RB, Rivas CI, Vera JC. Differential interaction of synthetic peptides from the carboxyl-terminal regulatory domain of tubulin with microtubule-associated proteins. The Embo Journal. 7: 1957-63. PMID 3416830  0.21
1983 Maccioni RB, Seeds NW. Limited proteolysis of tubulin: nucleotide stabilizes an active conformation. Biochemistry. 22: 1567-72. PMID 6849867  0.209
2009 Maccioni RB, Perry G. Preface Current Hypotheses and Research Milestones in Alzheimer's Disease. v-vi. DOI: 10.1007/978-0-387-87995-6  0.204
1986 Maccioni RB, Cann JR, Stewart JM. Interaction of substance P with tubulin. European Journal of Biochemistry / Febs. 154: 427-35. PMID 2417840 DOI: 10.1111/J.1432-1033.1986.Tb09415.X  0.201
1982 Mellado W, Slebe JC, Maccioni RB. Tubulin carbamoylation. Functional amino groups in microtubule assembly. The Biochemical Journal. 203: 675-81. PMID 7115308  0.195
1986 Maccioni RB, Serrano L, Avila J, Cann JR. Characterization and structural aspects of the enhanced assembly of tubulin after removal of its carboxyl-terminal domain. European Journal of Biochemistry / Febs. 156: 375-81. PMID 3699020 DOI: 10.1111/J.1432-1033.1986.Tb09593.X  0.19
1984 Serrano L, Avila J, Maccioni RB. Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction. Biochemistry. 23: 4675-81. PMID 6388633 DOI: 10.1021/Bi00315A024  0.188
1984 Serrano L, de la Torre J, Maccioni RB, Avila J. Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly. Proceedings of the National Academy of Sciences of the United States of America. 81: 5989-93. PMID 6385005  0.185
1983 Maccioni RB. Microtubule assembly affected by the presence of denatured tubulin. Biochemical and Biophysical Research Communications. 110: 463-9. PMID 6838530 DOI: 10.1016/0006-291X(83)91172-5  0.184
2004 Maccioni RB, Muñoz JP, Maccioni C. Biomedical Dimensions On Human Genome Research Acta Bioethica. 10: 75-80. DOI: 10.4067/S1726-569X2004000100010  0.181
1982 Maccioni RB, Seeds NW. Residual nucleotide and tubulin's ability to polymerize with nucleotide analogs. The Journal of Biological Chemistry. 257: 3334-8. PMID 7061478  0.167
1987 Avila J, Serrano L, Maccioni RB. Regulatory aspects of the colchicine interactions with tubulin. Molecular and Cellular Biochemistry. 73: 29-36. PMID 3543651 DOI: 10.1007/Bf00229373  0.167
2002 Maccioni RB. Opinion on the journal. Archives of Medical Research. 33: 512. PMID 12459327 DOI: 10.1016/S0188-4409(02)00388-0  0.161
1983 Maccioni RB, Seeds NW. Affinity labeling of tubulin's exchangeable guanosine 5'-triphosphate binding site. Biochemistry. 22: 1572-9. PMID 6849868  0.159
1986 Serrano L, Maccioni RB, Avila J. The carboxyterminal region of tubulin regulates its assembly into microtubules Annals of the New York Academy of Sciences. 642-644.  0.157
1984 Serrano L, Avila J, Maccioni RB. Limited proteolysis of tubulin and the localization of the binding site for colchicine. The Journal of Biological Chemistry. 259: 6607-11. PMID 6725263  0.155
1998 Paglini G, Pigino G, Kunda P, Morfini G, Maccioni R, Quiroga S, Ferreira A, Cáceres A. Evidence for the participation of the neuron-specific CDK5 activator p35 during laminin-enhanced axonal growth Journal of Neuroscience. 18: 9858-9869. PMID 9822744 DOI: 10.1523/Jneurosci.18-23-09858.1998  0.145
2015 Morales I, Arata L, Maccioni RB. Neuroinmmunomodulation in neurodegenerative diseases: New scientific evidence | La teoría de la neuroinmunomodulación en enfermedades neurodegenerativas: Nuevas evidencias científicas Revista Chilena De Neuro-Psiquiatria. 53: 53-56.  0.142
1991 Otter A, Scott PG, Maccioni RB, Kotovych G. The solution conformation of tubulin-beta(422-434)-NH2 and its Nac-DATADEQG-NH2 fragment based on NMR. Biopolymers. 31: 449-58. PMID 1863694 DOI: 10.1002/bip.360310410  0.14
2001 Maccioni RB. Cdk5. European Journal of Biochemistry. 268: 1517. PMID 29376562 DOI: 10.1046/j.1432-1327.2001.02022.x  0.139
1981 Maccioni RB, Mellado W. Characteristics of the in vitro assembly of brain tubulin of Cyprinus carpio Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 70: 375-380. DOI: 10.1016/0305-0491(81)90060-2  0.138
1986 Maccioni RB. Molecular cytology of microtubules. Revisiones Sobre Biologã­a Celular : Rbc. 8: 1-124. PMID 2892233  0.136
1982 Maccioni RB, Seeds NW. Involvement of tryptophan residues in colchicine binding and the assembly of tubulin. Biochemical and Biophysical Research Communications. 108: 896-903. PMID 6816238 DOI: 10.1016/0006-291X(82)90915-9  0.128
1986 Maccioni RB, Arechaga J. Transglutaminase (TG) involvement in early embryogenesis. Experimental Cell Research. 167: 266-70. PMID 2875896 DOI: 10.1016/0014-4827(86)90224-7  0.127
1984 Maccioni RB, Serrano L, Avila J. Studies on the tubulin domain for the interaction with MAP-2 Federation Proceedings. 43: no. 3476.  0.114
2010 Solinas C, Corpino M, MacCioni R, Pelosi U. Cow's milk protein allergy Journal of Maternal-Fetal and Neonatal Medicine. 23: 76-79. PMID 20836734 DOI: 10.3109/14767058.2010.512103  0.1
2001 Maccioni RB. Minireview series: Cdk5 European Journal of Biochemistry. 268: 1517. DOI: 10.1046/j.1432-1327.2001.02022.x  0.098
1978 Maccioni RB, Seeds NW. Enhancement of tubulin assembly as monitored by a rapid filtration assay. Archives of Biochemistry and Biophysics. 185: 262-71. PMID 623488 DOI: 10.1016/0003-9861(78)90166-2  0.097
1987 Sugiura M, Maccioni RB, Cann JR, York EJ, Stewart JM, Kotovych G. A proton magnetic resonance and a circular dichroism study of the solvent dependent conformation of the synthetic tubulin fragment Ac tubulin, alpha (430-441) amide and its interaction with substance-P. Journal of Biomolecular Structure & Dynamics. 4: 1105-17. PMID 2481463 DOI: 10.1080/07391102.1987.10507701  0.078
2021 Rao KSJ, Britton G, Rocha Arrieta LL, Garcia-Cairasco N, Lazarowski A, Palacios A, Camins Espuny A, Maccioni RB. Translational Research and Drug Discovery for Neurodegeneration: Challenges for Latin America. Journal of Alzheimer's Disease : Jad. PMID 34092644 DOI: 10.3233/JAD-210245  0.06
1983 Slebe JC, Herrera R, Hubert E, Ojeda A, Maccioni RB. Fructose 1,6-bisphosphatase: Dissociation of AMP cooperativity and AMP inhibition by carbamylation Journal of Protein Chemistry. 2: 437-443. DOI: 10.1007/BF01025417  0.05
1979 Maccioni RB, Hubert E, Slebe JC. Selective modification of fructose 1,6-bisphosphatase by periodate-oxidized AMP. Febs Letters. 102: 29-32. PMID 222616 DOI: 10.1016/0014-5793(79)80921-7  0.049
2002 Maccioni RB. Opinion on the Journal [2] Archives of Medical Research. 33: 512. DOI: 10.1016/S0188-4409(02)00388-0  0.01
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