R. Mark Wightman - Publications

Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Ultramicroelectrodes, Electrochemistry, Neurochemistry

306 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Walton LR, Verber M, Lee SH, Chao TH, Wightman RM, Shih YI. Simultaneous fMRI and fast-scan cyclic voltammetry bridges evoked oxygen and neurotransmitter dynamics across spatiotemporal scales. Neuroimage. 118634. PMID 34624504 DOI: 10.1016/j.neuroimage.2021.118634  0.319
2018 Johnson JA, Rodeberg NT, Wightman RM. Measurement of Basal Neurotransmitter Levels Using Convolution-Based Nonfaradaic Current Removal. Analytical Chemistry. PMID 29806450 DOI: 10.1021/acs.analchem.7b04682  0.422
2018 Bamford NS, Wightman RM, Sulzer D. Dopamine's Effects on Corticostriatal Synapses during Reward-Based Behaviors. Neuron. 97: 494-510. PMID 29420932 DOI: 10.1016/j.neuron.2018.01.006  0.466
2017 Hobbs CN, Holzberg G, Min AS, Wightman RM. Comparison of Spreading Depolarizations in the Motor Cortex and Nucleus Accumbens: Similar Patterns of Oxygen Responses and the Role of Dopamine. Acs Chemical Neuroscience. PMID 28820571 DOI: 10.1021/Acschemneuro.7B00266  0.822
2017 Johnson JA, Hobbs CN, Wightman RM. Removal of Differential Capacitive Interferences in Fast-Scan Cyclic Voltammetry. Analytical Chemistry. PMID 28488873 DOI: 10.1021/acs.analchem.7b01005  0.338
2017 Walton L, Boustead NG, Carroll S, Wightman RM. The Effects of Glutamate Receptor Activation on Local Oxygen Changes. Acs Chemical Neuroscience. PMID 28425701 DOI: 10.1021/acschemneuro.7b00088  0.309
2017 Fox ME, Wightman RM. Contrasting Regulation of Catecholamine Neurotransmission in the Behaving Brain: Pharmacological Insights from an Electrochemical Perspective. Pharmacological Reviews. 69: 12-32. PMID 28267676 DOI: 10.1124/Pr.116.012948  0.703
2017 Rodeberg NT, Sandberg SG, Johnson JA, Phillips PE, Wightman RM. Hitchhiker's Guide to Voltammetry: Acute and Chronic Electrodes for in vivo Fast-Scan Cyclic Voltammetry. Acs Chemical Neuroscience. PMID 28127962 DOI: 10.1021/acschemneuro.6b00393  0.823
2016 Fox ME, Bucher ES, Johnson JA, Wightman RM. Medullary norepinephrine projections release norepinephrine into the contralateral bed nucleus of the stria terminalis. Acs Chemical Neuroscience. PMID 27617735 DOI: 10.1021/Acschemneuro.6B00210  0.82
2016 Cameron CM, Wightman RM, Carelli RM. One month of cocaine abstinence potentiates rapid dopamine signaling in the nucleus accumbens core. Neuropharmacology. PMID 27616012 DOI: 10.1016/J.Neuropharm.2016.09.006  0.774
2016 Rodeberg NT, Johnson JA, Bucher ES, Wightman RM. Dopamine dynamics during continuous intracranial self-stimulation: effect of waveform on fast-scan cyclic voltammetry data. Acs Chemical Neuroscience. PMID 27548680 DOI: 10.1021/Acschemneuro.6B00142  0.866
2016 Fox ME, Rodeberg NT, Wightman RM. Reciprocal Catecholamine Changes during Opiate Exposure and Withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27461081 DOI: 10.1038/Npp.2016.135  0.735
2016 Fox ME, Mikhailova MA, Bass CE, Takmakov P, Gainetdinov RR, Budygin EA, Wightman RM. Cross-hemispheric dopamine projections have functional significance. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298371 DOI: 10.1073/Pnas.1603629113  0.859
2016 Owesson-White C, Belle AM, Herr NR, Peele JL, Gowrishankar P, Carelli RM, Wightman RM. Cue-Evoked Dopamine Release Rapidly Modulates D2 Neurons in the Nucleus Accumbens During Motivated Behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6011-21. PMID 27251622 DOI: 10.1523/Jneurosci.0393-16.2016  0.846
2016 Kirkpatrick DC, Wightman RM. Evaluation of Drug Concentrations Delivered by Microiontophoresis. Analytical Chemistry. PMID 27212615 DOI: 10.1021/acs.analchem.6b01211  0.456
2016 Walton LR, Edwards MA, McCarty GS, Wightman RM. Design and characterization of a microfabricated hydrogen clearance blood flow sensor. Journal of Neuroscience Methods. PMID 27102042 DOI: 10.1016/J.Jneumeth.2016.04.014  0.537
2016 Kirkpatrick DC, Walton LR, Edwards MA, Wightman RM. Quantitative analysis of iontophoretic drug delivery from micropipettes. The Analyst. PMID 26890395 DOI: 10.1039/c5an02530c  0.509
2016 Dankoski EC, Carroll S, Wightman RM. Acute SSRIs regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of Neurochemistry. PMID 26749030 DOI: 10.1111/Jnc.13528  0.808
2016 Wightman RM. Analytical tools propel discoveries about dopamine neurotransmission Intrinsic Activity. 4: A1.3. DOI: 10.25006/IA.4.S2-A1.3  0.39
2015 Schultz W, Carelli RM, Wightman RM. Phasic dopamine signals: from subjective reward value to formal economic utility. Current Opinion in Behavioral Sciences. 5: 147-154. PMID 26719853 DOI: 10.1016/j.cobeha.2015.09.006  0.775
2015 Rodeberg NT, Johnson JA, Cameron CM, Saddoris MP, Carelli RM, Wightman RM. Construction of Training Sets for Valid Calibration of in Vivo Cyclic Voltammetric Data by Principal Component Analysis. Analytical Chemistry. PMID 26477708 DOI: 10.1021/Acs.Analchem.5B03222  0.713
2015 Dengler AK, Wightman RM, McCarty GS. Microfabricated Collector-Generator Electrode Sensor for Measuring Absolute pH and Oxygen Concentrations. Analytical Chemistry. 87: 10556-64. PMID 26375039 DOI: 10.1021/Acs.Analchem.5B02866  0.321
2015 Saddoris MP, Cacciapaglia F, Wightman RM, Carelli RM. Differential Dopamine Release Dynamics in the Nucleus Accumbens Core and Shell Reveal Complementary Signals for Error Prediction and Incentive Motivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11572-82. PMID 26290234 DOI: 10.1523/Jneurosci.2344-15.2015  0.792
2015 Bucher ES, Wightman RM. Electrochemical Analysis of Neurotransmitters. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 8: 239-61. PMID 25939038 DOI: 10.1146/Annurev-Anchem-071114-040426  0.829
2015 Fox ME, Studebaker RI, Swofford NJ, Wightman RM. Stress and Drug Dependence Differentially Modulate Norepinephrine Signaling in Animals with Varied HPA Axis Function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1752-61. PMID 25601230 DOI: 10.1038/Npp.2015.23  0.635
2015 Park J, Bucher ES, Budygin EA, Wightman RM. Norepinephrine and dopamine transmission in 2 limbic regions differentially respond to acute noxious stimulation. Pain. 156: 318-27. PMID 25599453 DOI: 10.1097/01.J.Pain.0000460312.79195.Ed  0.856
2015 Masoud ST, Vecchio LM, Bergeron Y, Hossain MM, Nguyen LT, Bermejo MK, Kile B, Sotnikova TD, Siesser WB, Gainetdinov RR, Wightman RM, Caron MG, Richardson JR, Miller GW, Ramsey AJ, et al. Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits. Neurobiology of Disease. 74: 66-75. PMID 25447236 DOI: 10.1016/J.Nbd.2014.10.016  0.848
2015 Saddoris MP, Cacciapaglia F, Wightman RM, Carelli RM. Differential dopamine release dynamics in the nucleus accumbens core and shell reveal complementary signals for error prediction and incentive motivation Journal of Neuroscience. 35: 11572-11582. DOI: 10.1523/JNEUROSCI.2344-15.2015  0.769
2014 Cameron CM, Wightman RM, Carelli RM. Dynamics of rapid dopamine release in the nucleus accumbens during goal-directed behaviors for cocaine versus natural rewards. Neuropharmacology. 86: 319-28. PMID 25174553 DOI: 10.1016/J.Neuropharm.2014.08.006  0.807
2014 Kirkpatrick DC, Edwards MA, Flowers PA, Wightman RM. Characterization of solute distribution following iontophoresis from a micropipet. Analytical Chemistry. 86: 9909-16. PMID 25157675 DOI: 10.1021/ac5026072  0.553
2014 Dankoski EC, Agster KL, Fox ME, Moy SS, Wightman RM. Facilitation of serotonin signaling by SSRIs is attenuated by social isolation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2928-37. PMID 24981046 DOI: 10.1038/Npp.2014.162  0.803
2014 Bucher ES, Fox ME, Kim L, Kirkpatrick DC, Rodeberg NT, Belle AM, Wightman RM. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1128-37. PMID 24714037 DOI: 10.1038/Jcbfm.2014.60  0.816
2013 Bucher ES, Brooks K, Verber MD, Keithley RB, Owesson-White C, Carroll S, Takmakov P, McKinney CJ, Wightman RM. Flexible software platform for fast-scan cyclic voltammetry data acquisition and analysis. Analytical Chemistry. 85: 10344-53. PMID 24083898 DOI: 10.1021/Ac402263X  0.78
2013 Street SE, Kramer NJ, Walsh PL, Taylor-Blake B, Yadav MC, King IF, Vihko P, Wightman RM, Millán JL, Zylka MJ. Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11314-22. PMID 23825434 DOI: 10.1523/Jneurosci.0133-13.2013  0.587
2013 Dankoski EC, Wightman RM. Monitoring serotonin signaling on a subsecond time scale. Frontiers in Integrative Neuroscience. 7: 44. PMID 23760548 DOI: 10.3389/fnint.2013.00044  0.811
2013 Wickham RJ, Solecki W, Rathbun LR, Neugebauer NM, Wightman RM, Addy NA. Advances in studying phasic dopamine signaling in brain reward mechanisms. Frontiers in Bioscience (Elite Edition). 5: 982-99. PMID 23747914 DOI: 10.2741/E678  0.747
2013 Belle AM, Owesson-White C, Herr NR, Carelli RM, Wightman RM. Controlled iontophoresis coupled with fast-scan cyclic voltammetry/electrophysiology in awake, freely moving animals. Acs Chemical Neuroscience. 4: 761-71. PMID 23480099 DOI: 10.1021/Cn400031V  0.853
2013 McElligott ZA, Fox ME, Walsh PL, Urban DJ, Ferrel MS, Roth BL, Wightman RM. Noradrenergic synaptic function in the bed nucleus of the stria terminalis varies in animal models of anxiety and addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1665-73. PMID 23467277 DOI: 10.1038/Npp.2013.63  0.806
2013 Herr NR, Wightman RM. Improved techniques for examining rapid dopamine signaling with iontophoresis. Frontiers in Bioscience (Elite Edition). 5: 249-57. PMID 23276986 DOI: 10.2741/E612  0.811
2013 Park J, Bucher ES, Fontillas K, Owesson-White C, Ariansen JL, Carelli RM, Wightman RM. Opposing catecholamine changes in the bed nucleus of the stria terminalis during intracranial self-stimulation and its extinction. Biological Psychiatry. 74: 69-76. PMID 23260335 DOI: 10.1016/J.Biopsych.2012.11.008  0.843
2013 Park J, Bucher ES, Wightman RM. Opposing Regulation of Norepinephrine and Dopamine in Rat Limbic Brain Regions in Response to Aversive Stimuli Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 159. DOI: 10.1016/B978-0-12-800044-1.00141-0  0.819
2012 Riday TT, Dankoski EC, Krouse MC, Fish EW, Walsh PL, Han JE, Hodge CW, Wightman RM, Philpot BD, Malanga CJ. Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome. The Journal of Clinical Investigation. 122: 4544-54. PMID 23143301 DOI: 10.1172/Jci61888  0.836
2012 Ariansen JL, Heien ML, Hermans A, Phillips PE, Hernadi I, Bermudez MA, Schultz W, Wightman RM. Monitoring extracellular pH, oxygen, and dopamine during reward delivery in the striatum of primates. Frontiers in Behavioral Neuroscience. 6: 36. PMID 22783176 DOI: 10.3389/Fnbeh.2012.00036  0.804
2012 Hashemi P, Dankoski EC, Lama R, Wood KM, Takmakov P, Wightman RM. Brain dopamine and serotonin differ in regulation and its consequences. Proceedings of the National Academy of Sciences of the United States of America. 109: 11510-5. PMID 22778401 DOI: 10.1073/Pnas.1201547109  0.841
2012 Kile BM, Walsh PL, McElligott ZA, Bucher ES, Guillot TS, Salahpour A, Caron MG, Wightman RM. Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry. Acs Chemical Neuroscience. 3: 285-292. PMID 22708011 DOI: 10.1021/Cn200119U  0.835
2012 Owesson-White CA, Roitman MF, Sombers LA, Belle AM, Keithley RB, Peele JL, Carelli RM, Wightman RM. Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens. Journal of Neurochemistry. 121: 252-62. PMID 22296263 DOI: 10.1111/J.1471-4159.2012.07677.X  0.85
2012 Cacciapaglia F, Saddoris MP, Wightman RM, Carelli RM. Differential dopamine release dynamics in the nucleus accumbens core and shell track distinct aspects of goal-directed behavior for sucrose. Neuropharmacology. 62: 2050-6. PMID 22261383 DOI: 10.1016/J.Neuropharm.2011.12.027  0.811
2012 Herr NR, Park J, McElligott ZA, Belle AM, Carelli RM, Wightman RM. In vivo voltammetry monitoring of electrically evoked extracellular norepinephrine in subregions of the bed nucleus of the stria terminalis. Journal of Neurophysiology. 107: 1731-7. PMID 22190618 DOI: 10.1152/Jn.00620.2011  0.824
2012 Park J, Wheeler RA, Fontillas K, Keithley RB, Carelli RM, Wightman RM. Catecholamines in the bed nucleus of the stria terminalis reciprocally respond to reward and aversion. Biological Psychiatry. 71: 327-34. PMID 22115620 DOI: 10.1016/J.Biopsych.2011.10.017  0.826
2012 Budygin EA, Park J, Bass CE, Grinevich VP, Bonin KD, Wightman RM. Aversive stimulus differentially triggers subsecond dopamine release in reward regions. Neuroscience. 201: 331-7. PMID 22108611 DOI: 10.1016/J.Neuroscience.2011.10.056  0.805
2012 Sugam JA, Day JJ, Wightman RM, Carelli RM. Phasic nucleus accumbens dopamine encodes risk-based decision-making behavior. Biological Psychiatry. 71: 199-205. PMID 22055017 DOI: 10.1016/J.Biopsych.2011.09.029  0.773
2011 Hashemi P, Walsh PL, Guillot TS, Gras-Najjar J, Takmakov P, Crews FT, Wightman RM. Chronically Implanted, Nafion-Coated Ag/AgCl Reference Electrodes for Neurochemical Applications. Acs Chemical Neuroscience. 2: 658-666. PMID 22125666 DOI: 10.1021/Cn2000684  0.8
2011 Street SE, Walsh PL, Sowa NA, Taylor-Blake B, Guillot TS, Vihko P, Wightman RM, Zylka MJ. PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine. Molecular Pain. 7: 80. PMID 22011440 DOI: 10.1186/1744-8069-7-80  0.762
2011 Keithley RB, Wightman RM. Assessing principal component regression prediction of neurochemicals detected with fast-scan cyclic voltammetry. Acs Chemical Neuroscience. 2: 514-525. PMID 21966586 DOI: 10.1021/Cn200035U  0.756
2011 Cacciapaglia F, Wightman RM, Carelli RM. Rapid dopamine signaling differentially modulates distinct microcircuits within the nucleus accumbens during sucrose-directed behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13860-9. PMID 21957248 DOI: 10.1523/JNEUROSCI.1340-11.2011  0.812
2011 Park J, Takmakov P, Wightman RM. In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry. Journal of Neurochemistry. 119: 932-44. PMID 21933188 DOI: 10.1111/J.1471-4159.2011.07494.X  0.839
2011 Takmakov P, McKinney CJ, Carelli RM, Wightman RM. Instrumentation for fast-scan cyclic voltammetry combined with electrophysiology for behavioral experiments in freely moving animals. The Review of Scientific Instruments. 82: 074302. PMID 21806203 DOI: 10.1063/1.3610651  0.835
2011 Hashemi P, Dankoski EC, Wood KM, Ambrose RE, Wightman RM. In vivo electrochemical evidence for simultaneous 5-HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation. Journal of Neurochemistry. 118: 749-59. PMID 21682723 DOI: 10.1111/J.1471-4159.2011.07352.X  0.799
2011 Wheeler RA, Aragona BJ, Fuhrmann KA, Jones JL, Day JJ, Cacciapaglia F, Wightman RM, Carelli RM. Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state. Biological Psychiatry. 69: 1067-74. PMID 21481843 DOI: 10.1016/J.Biopsych.2011.02.014  0.785
2011 Keithley RB, Takmakov P, Bucher ES, Belle AM, Owesson-White CA, Park J, Wightman RM. Higher sensitivity dopamine measurements with faster-scan cyclic voltammetry. Analytical Chemistry. 83: 3563-71. PMID 21473572 DOI: 10.1021/Ac200143V  0.806
2011 Walsh PL, Petrovic J, Wightman RM. Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry. American Journal of Physiology. Cell Physiology. 300: C49-57. PMID 21048165 DOI: 10.1152/Ajpcell.00332.2010  0.724
2010 Herr NR, Daniel KB, Belle AM, Carelli RM, Wightman RM. Probing presynaptic regulation of extracellular dopamine with iontophoresis. Acs Chemical Neuroscience. 1: 627-638. PMID 21060714 DOI: 10.1021/Cn100056R  0.86
2010 Takmakov P, Zachek MK, Keithley RB, Bucher ES, McCarty GS, Wightman RM. Characterization of local pH changes in brain using fast-scan cyclic voltammetry with carbon microelectrodes. Analytical Chemistry. 82: 9892-900. PMID 21047096 DOI: 10.1021/Ac102399N  0.786
2010 Kile BM, Guillot TS, Venton BJ, Wetsel WC, Augustine GJ, Wightman RM. Synapsins differentially control dopamine and serotonin release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9762-70. PMID 20660258 DOI: 10.1523/Jneurosci.2071-09.2010  0.85
2010 Beyene M, Carelli RM, Wightman RM. Cue-evoked dopamine release in the nucleus accumbens shell tracks reinforcer magnitude during intracranial self-stimulation. Neuroscience. 169: 1682-8. PMID 20600644 DOI: 10.1016/J.Neuroscience.2010.06.047  0.855
2010 Addy NA, Daberkow DP, Ford JN, Garris PA, Wightman RM. Sensitization of rapid dopamine signaling in the nucleus accumbens core and shell after repeated cocaine in rats. Journal of Neurophysiology. 104: 922-31. PMID 20554845 DOI: 10.1152/Jn.00413.2010  0.828
2010 Keithley RB, Carelli RM, Wightman RM. Rank estimation and the multivariate analysis of in vivo fast-scan cyclic voltammetric data. Analytical Chemistry. 82: 5541-51. PMID 20527815 DOI: 10.1021/Ac100413T  0.774
2010 Annangudi SP, Luszpak AE, Kim SH, Ren S, Hatcher NG, Weiler IJ, Thornley KT, Kile BM, Wightman RM, Greenough WT, Sweedler JV. Neuropeptide Release is Impaired in a Mouse Model of Fragile X Mental Retardation Syndrome. Acs Chemical Neuroscience. 1: 306-314. PMID 20495672 DOI: 10.1021/Cn900036X  0.781
2010 Zachek MK, Park J, Takmakov P, Wightman RM, McCarty GS. Microfabricated FSCV-compatible microelectrode array for real-time monitoring of heterogeneous dopamine release. The Analyst. 135: 1556-63. PMID 20464031 DOI: 10.1039/C0An00114G  0.793
2010 Day JJ, Jones JL, Wightman RM, Carelli RM. Phasic nucleus accumbens dopamine release encodes effort- and delay-related costs. Biological Psychiatry. 68: 306-9. PMID 20452572 DOI: 10.1016/j.biopsych.2010.03.026  0.775
2010 Park J, Aragona BJ, Kile BM, Carelli RM, Wightman RM. In vivo voltammetric monitoring of catecholamine release in subterritories of the nucleus accumbens shell. Neuroscience. 169: 132-42. PMID 20451589 DOI: 10.1016/J.Neuroscience.2010.04.076  0.864
2010 Petrovic J, Walsh PL, Thornley KT, Miller CE, Wightman RM. Real-time monitoring of chemical transmission in slices of the murine adrenal gland. Endocrinology. 151: 1773-83. PMID 20181796 DOI: 10.1210/En.2009-1324  0.81
2010 Takmakov P, Zachek MK, Keithley RB, Walsh PL, Donley C, McCarty GS, Wightman RM. Carbon microelectrodes with a renewable surface. Analytical Chemistry. 82: 2020-8. PMID 20146453 DOI: 10.1021/Ac902753X  0.785
2010 Jones JL, Day JJ, Aragona BJ, Wheeler RA, Wightman RM, Carelli RM. Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding. Biological Psychiatry. 67: 737-44. PMID 20044074 DOI: 10.1016/J.Biopsych.2009.11.006  0.813
2010 Zachek MK, Takmakov P, Park J, Wightman RM, McCarty GS. Simultaneous monitoring of dopamine concentration at spatially different brain locations in vivo. Biosensors & Bioelectronics. 25: 1179-85. PMID 19896822 DOI: 10.1016/J.Bios.2009.10.008  0.811
2010 Keithley RB, Wightman RM, Heien ML. Erratum to “Multivariate concentration determination using principal component regression with residual analysis” [Trends Anal. Chem. 28 (2009) 1127–1136] Trac Trends in Analytical Chemistry. 29: 110. DOI: 10.1016/S0165-9936(09)00282-9  0.754
2009 Keithley RB, Heien ML, Wightman RM. Multivariate concentration determination using principal component regression with residual analysis. Trends in Analytical Chemistry : Trac. 28: 1127-1136. PMID 20160977 DOI: 10.1016/J.Trac.2009.07.002  0.763
2009 Park J, Kile BM, Wightman RM. In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus. The European Journal of Neuroscience. 30: 2121-33. PMID 20128849 DOI: 10.1111/J.1460-9568.2009.07005.X  0.831
2009 Aragona BJ, Day JJ, Roitman MF, Cleaveland NA, Wightman RM, Carelli RM. Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats. The European Journal of Neuroscience. 30: 1889-99. PMID 19912327 DOI: 10.1111/j.1460-9568.2009.07027.x  0.788
2009 Hashemi P, Dankoski EC, Petrovic J, Keithley RB, Wightman RM. Voltammetric detection of 5-hydroxytryptamine release in the rat brain. Analytical Chemistry. 81: 9462-71. PMID 19827792 DOI: 10.1021/Ac9018846  0.8
2009 Owesson-White CA, Ariansen J, Stuber GD, Cleaveland NA, Cheer JF, Wightman RM, Carelli RM. Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell. The European Journal of Neuroscience. 30: 1117-27. PMID 19735286 DOI: 10.1111/j.1460-9568.2009.06916.x  0.86
2009 Kita JM, Kile BM, Parker LE, Wightman RM. In vivo measurement of somatodendritic release of dopamine in the ventral tegmental area. Synapse (New York, N.Y.). 63: 951-60. PMID 19593821 DOI: 10.1002/Syn.20676  0.867
2009 Zachek MK, Takmakov P, Moody B, Wightman RM, McCarty GS. Simultaneous decoupled detection of dopamine and oxygen using pyrolyzed carbon microarrays and fast-scan cyclic voltammetry. Analytical Chemistry. 81: 6258-65. PMID 19552423 DOI: 10.1021/Ac900790M  0.788
2009 Caron MG, Wightman RM. "To learn, you must pay attention." Molecular insights into teachers' wisdom. Proceedings of the National Academy of Sciences of the United States of America. 106: 7267-8. PMID 19416916 DOI: 10.1073/pnas.0903306106  0.6
2009 Robinson DL, Howard EC, McConnell S, Gonzales RA, Wightman RM. Disparity between tonic and phasic ethanol-induced dopamine increases in the nucleus accumbens of rats. Alcoholism, Clinical and Experimental Research. 33: 1187-96. PMID 19389195 DOI: 10.1111/J.1530-0277.2009.00942.X  0.81
2009 Sombers LA, Beyene M, Carelli RM, Wightman RM. Synaptic overflow of dopamine in the nucleus accumbens arises from neuronal activity in the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1735-42. PMID 19211880 DOI: 10.1523/Jneurosci.5562-08.2009  0.854
2008 Zachek MK, Hermans A, Wightman RM, McCarty GS. Electrochemical Dopamine Detection: Comparing Gold and Carbon Fiber Microelectrodes using Background Subtracted Fast Scan Cyclic Voltammetry. Journal of Electroanalytical Chemistry (Lausanne, Switzerland). 614: 113-120. PMID 19319208 DOI: 10.1016/J.Jelechem.2007.11.007  0.666
2008 Roitman MF, Wheeler RA, Wightman RM, Carelli RM. Real-time chemical responses in the nucleus accumbens differentiate rewarding and aversive stimuli. Nature Neuroscience. 11: 1376-7. PMID 18978779 DOI: 10.1038/Nn.2219  0.768
2008 Herr NR, Kile BM, Carelli RM, Wightman RM. Electroosmotic flow and its contribution to iontophoretic delivery. Analytical Chemistry. 80: 8635-41. PMID 18947198 DOI: 10.1021/Ac801547A  0.774
2008 Aragona BJ, Cleaveland NA, Stuber GD, Day JJ, Carelli RM, Wightman RM. Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8821-31. PMID 18753384 DOI: 10.1523/JNEUROSCI.2225-08.2008  0.849
2008 Shin JH, Privett BJ, Kita JM, Wightman RM, Schoenfisch MH. Fluorinated xerogel-derived microelectrodes for amperometric nitric oxide sensing. Analytical Chemistry. 80: 6850-9. PMID 18714964 DOI: 10.1021/Ac800185X  0.77
2008 Owesson-White CA, Cheer JF, Beyene M, Carelli RM, Wightman RM. Dynamic changes in accumbens dopamine correlate with learning during intracranial self-stimulation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11957-62. PMID 18689678 DOI: 10.1073/Pnas.0803896105  0.852
2008 Kita JM, Wightman RM. Microelectrodes for studying neurobiology. Current Opinion in Chemical Biology. 12: 491-6. PMID 18675377 DOI: 10.1016/J.Cbpa.2008.06.035  0.774
2008 Robinson DL, Hermans A, Seipel AT, Wightman RM. Monitoring rapid chemical communication in the brain. Chemical Reviews. 108: 2554-84. PMID 18576692 DOI: 10.1021/Cr068081Q  0.841
2008 Hermans A, Keithley RB, Kita JM, Sombers LA, Wightman RM. Dopamine detection with fast-scan cyclic voltammetry used with analog background subtraction. Analytical Chemistry. 80: 4040-8. PMID 18433146 DOI: 10.1021/Ac800108J  0.847
2008 Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/Pnas.0707646105  0.834
2007 Hashemi P, Wightman RM. Paying attention with the latest technology. Neuron. 56: 4-5. PMID 17920007 DOI: 10.1016/J.Neuron.2007.09.022  0.661
2007 Wightman RM, Heien ML, Wassum KM, Sombers LA, Aragona BJ, Khan AS, Ariansen JL, Cheer JF, Phillips PE, Carelli RM. Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens. The European Journal of Neuroscience. 26: 2046-54. PMID 17868375 DOI: 10.1111/j.1460-9568.2007.05772.x  0.854
2007 Johnson MA, Villanueva M, Haynes CL, Seipel AT, Buhler LA, Wightman RM. Catecholamine exocytosis is diminished in R6/2 Huntington's disease model mice. Journal of Neurochemistry. 103: 2102-10. PMID 17868298 DOI: 10.1111/J.1471-4159.2007.04908.X  0.819
2007 Kita JM, Parker LE, Phillips PE, Garris PA, Wightman RM. Paradoxical modulation of short-term facilitation of dopamine release by dopamine autoreceptors. Journal of Neurochemistry. 102: 1115-24. PMID 17663751 DOI: 10.1111/J.1471-4159.2007.04621.X  0.86
2007 Day JJ, Roitman MF, Wightman RM, Carelli RM. Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens. Nature Neuroscience. 10: 1020-8. PMID 17603481 DOI: 10.1038/nn1923  0.801
2007 Haynes CL, Siff LN, Wightman RM. Temperature-dependent differences between readily releasable and reserve pool vesicles in chromaffin cells. Biochimica Et Biophysica Acta. 1773: 728-35. PMID 17467077 DOI: 10.1016/J.Bbamcr.2007.03.013  0.546
2007 Cheer JF, Aragona BJ, Heien ML, Seipel AT, Carelli RM, Wightman RM. Coordinated accumbal dopamine release and neural activity drive goal-directed behavior. Neuron. 54: 237-44. PMID 17442245 DOI: 10.1016/j.neuron.2007.03.021  0.852
2007 Villanueva M, Wightman RM. Facilitation of quantal release induced by a D1-like receptor on bovine chromaffin cells. Biochemistry. 46: 3881-7. PMID 17338553 DOI: 10.1021/Bi602661P  0.638
2007 Cheer JF, Wassum KM, Sombers LA, Heien ML, Ariansen JL, Aragona BJ, Phillips PE, Wightman RM. Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 791-5. PMID 17251418 DOI: 10.1523/JNEUROSCI.4152-06.2007  0.847
2007 Venton BJ, Wightman RM. Pharmacologically induced, subsecond dopamine transients in the caudate-putamen of the anesthetized rat. Synapse (New York, N.Y.). 61: 37-9. PMID 17068772 DOI: 10.1002/syn.20343  0.804
2006 Villanueva M, Thornley K, Augustine GJ, Wightman RM. Synapsin II negatively regulates catecholamine release. Brain Cell Biology. 35: 125-36. PMID 17957479 DOI: 10.1007/S11068-007-9015-2  0.807
2006 Hermans A, Wightman RM. Conical tungsten tips as substrates for the preparation of ultramicroelectrodes. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 10348-53. PMID 17129002 DOI: 10.1021/La061209E  0.582
2006 Cheer JF, Wassum KM, Wightman RM. Cannabinoid modulation of electrically evoked pH and oxygen transients in the nucleus accumbens of awake rats. Journal of Neurochemistry. 97: 1145-54. PMID 16686693 DOI: 10.1111/j.1471-4159.2006.03860.x  0.78
2006 Haynes CL, Buhler LA, Wightman RM. Vesicular Ca(2+) -induced secretion promoted by intracellular pH-gradient disruption. Biophysical Chemistry. 123: 20-4. PMID 16678962 DOI: 10.1016/J.Bpc.2006.04.005  0.501
2006 Heien ML, Wightman RM. Phasic dopamine signaling during behavior, reward, and disease states. Cns & Neurological Disorders Drug Targets. 5: 99-108. PMID 16613556 DOI: 10.2174/187152706784111605  0.754
2006 Johnson MA, Rajan V, Miller CE, Wightman RM. Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease. Journal of Neurochemistry. 97: 737-46. PMID 16573654 DOI: 10.1111/J.1471-4159.2006.03762.X  0.723
2006 Venton BJ, Seipel AT, Phillips PE, Wetsel WC, Gitler D, Greengard P, Augustine GJ, Wightman RM. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3206-9. PMID 16554471 DOI: 10.1523/Jneurosci.4901-04.2006  0.854
2006 Wightman RM. Detection technologies. Probing cellular chemistry in biological systems with microelectrodes. Science (New York, N.Y.). 311: 1570-4. PMID 16543451 DOI: 10.1126/science.1120027  0.322
2006 Hermans A, Seipel AT, Miller CE, Wightman RM. Carbon-fiber microelectrodes modified with 4-sulfobenzene have increased sensitivity and selectivity for catecholamines. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 1964-9. PMID 16489775 DOI: 10.1021/La053032E  0.819
2006 Dudko OK, Szabo A, Ketter J, Wightman RM. Analytic theory of the current at inlaid planar ultramicroelectrodes: Comparison with experiments on elliptic disks Journal of Electroanalytical Chemistry. 586: 18-22. DOI: 10.1016/J.Jelechem.2005.09.016  0.776
2005 Cheer JF, Heien ML, Garris PA, Carelli RM, Wightman RM. Simultaneous dopamine and single-unit recordings reveal accumbens GABAergic responses: implications for intracranial self-stimulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 19150-5. PMID 16380429 DOI: 10.1073/pnas.0509607102  0.849
2005 Heien ML, Khan AS, Ariansen JL, Cheer JF, Phillips PE, Wassum KM, Wightman RM. Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats. Proceedings of the National Academy of Sciences of the United States of America. 102: 10023-8. PMID 16006505 DOI: 10.1073/pnas.0504657102  0.862
2005 Stuber GD, Wightman RM, Carelli RM. Extinction of cocaine self-administration reveals functionally and temporally distinct dopaminergic signals in the nucleus accumbens. Neuron. 46: 661-9. PMID 15944133 DOI: 10.1016/j.neuron.2005.04.036  0.826
2005 Lavin A, Nogueira L, Lapish CC, Wightman RM, Phillips PE, Seamans JK. Mesocortical dopamine neurons operate in distinct temporal domains using multimodal signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5013-23. PMID 15901782 DOI: 10.1523/Jneurosci.0557-05.2005  0.663
2005 Robinson DL, Volz TJ, Schenk JO, Wightman RM. Acute ethanol decreases dopamine transporter velocity in rat striatum: in vivo and in vitro electrochemical measurements. Alcoholism, Clinical and Experimental Research. 29: 746-55. PMID 15897718 DOI: 10.1097/01.Alc.0000164362.21484.14  0.816
2005 Stuber GD, Roitman MF, Phillips PE, Carelli RM, Wightman RM. Rapid dopamine signaling in the nucleus accumbens during contingent and noncontingent cocaine administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 853-63. PMID 15549053 DOI: 10.1038/sj.npp.1300619  0.823
2005 Puopolo M, Hochstetler SE, Gustincich S, Wightman RM, Raviola E. Extrasynaptic release of dopamine and volume transmission in the Retina Dendritic Neurotransmitter Release. 175-189. DOI: 10.1007/0-387-23696-1_12  0.413
2005 Forry SP, Wightman RM. Organic ECL Systems Cheminform. 36. DOI: 10.1002/chin.200509289  0.631
2004 Garris PA, Ensman R, Poehlman J, Alexander A, Langley PE, Sandberg SG, Greco PG, Wightman RM, Rebec GV. Wireless transmission of fast-scan cyclic voltammetry at a carbon-fiber microelectrode: proof of principle. Journal of Neuroscience Methods. 140: 103-15. PMID 15589340 DOI: 10.1016/j.jneumeth.2004.04.043  0.82
2004 Carelli RM, Wightman RM. Functional microcircuitry in the accumbens underlying drug addiction: insights from real-time signaling during behavior. Current Opinion in Neurobiology. 14: 763-8. PMID 15582381 DOI: 10.1016/j.conb.2004.10.001  0.741
2004 Heien ML, Johnson MA, Wightman RM. Resolving neurotransmitters detected by fast-scan cyclic voltammetry. Analytical Chemistry. 76: 5697-704. PMID 15456288 DOI: 10.1021/ac0491509  0.733
2004 Forry SP, Murray JR, Heien ML, Locascio LE, Wightman RM. Probing electric fields inside microfluidic channels during electroosmotic flow with fast-scan cyclic voltammetry. Analytical Chemistry. 76: 4945-50. PMID 15373427 DOI: 10.1021/Ac049591S  0.765
2004 Song Y, Heien ML, Jimenez V, Wightman RM, Murray RW. Voltammetric detection of metal nanoparticles separated by liquid chromatography. Analytical Chemistry. 76: 4911-9. PMID 15373423 DOI: 10.1021/Ac049223O  0.775
2004 Ketter JB, Wightman RM. Tuning emissive states in electrogenerated chemiluminescence. Journal of the American Chemical Society. 126: 10183-9. PMID 15303894 DOI: 10.1021/Ja047602T  0.764
2004 Robinson DL, Wightman RM. Nomifensine amplifies subsecond dopamine signals in the ventral striatum of freely-moving rats. Journal of Neurochemistry. 90: 894-903. PMID 15287895 DOI: 10.1111/j.1471-4159.2004.02559.x  0.781
2004 Cheer JF, Wassum KM, Heien ML, Phillips PE, Wightman RM. Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4393-400. PMID 15128853 DOI: 10.1523/JNEUROSCI.0529-04.2004  0.864
2004 Wightman RM, Haynes CL. Synaptic vesicles really do kiss and run. Nature Neuroscience. 7: 321-2. PMID 15048116 DOI: 10.1038/Nn0404-321  0.521
2004 Phillips PE, Wightman RM. Extrasynaptic dopamine and phasic neuronal activity. Nature Neuroscience. 7: 199; author reply 19. PMID 14983175 DOI: 10.1038/nn0304-199a  0.626
2004 Montague PR, McClure SM, Baldwin PR, Phillips PE, Budygin EA, Stuber GD, Kilpatrick MR, Wightman RM. Dynamic gain control of dopamine delivery in freely moving animals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1754-9. PMID 14973252 DOI: 10.1523/Jneurosci.4279-03.2004  0.855
2004 Roitman MF, Stuber GD, Phillips PE, Wightman RM, Carelli RM. Dopamine operates as a subsecond modulator of food seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1265-71. PMID 14960596 DOI: 10.1523/JNEUROSCI.3823-03.2004  0.861
2004 Ketter JB, Forry SP, Wightman RM, Feldberg SW. Use of DigiSim to Model Cyclic Voltammetric and Photonic Responses in Electrogenerated Chemiluminescent Systems Electrochemical and Solid-State Letters. 7: E18-E22. DOI: 10.1149/1.1642576  0.765
2004 Wightman RM, Forry SP, Maus R, Badocco D, Pastore P. Rate-determining step in the electrogenerated chemiluminescence from tertiary amines with tris(2,2′-bipyridyl)rathenium(II) Journal of Physical Chemistry B. 108: 19119-19125. DOI: 10.1021/Jp036034L  0.767
2003 Heien ML, Phillips PE, Stuber GD, Seipel AT, Wightman RM. Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity. The Analyst. 128: 1413-9. PMID 14737224 DOI: 10.1039/b307024g  0.84
2003 Venton BJ, Zhang H, Garris PA, Phillips PE, Sulzer D, Wightman RM. Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing. Journal of Neurochemistry. 87: 1284-95. PMID 14622108 DOI: 10.1111/j.1471-4159.2004.02418.x  0.855
2003 Robinson DL, Venton BJ, Heien ML, Wightman RM. Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo. Clinical Chemistry. 49: 1763-73. PMID 14500617 DOI: 10.1373/49.10.1763  0.861
2003 Garris PA, Budygin EA, Phillips PE, Venton BJ, Robinson DL, Bergstrom BP, Rebec GV, Wightman RM. A role for presynaptic mechanisms in the actions of nomifensine and haloperidol. Neuroscience. 118: 819-29. PMID 12710989 DOI: 10.1016/S0306-4522(03)00005-8  0.835
2003 Phillips PE, Stuber GD, Heien ML, Wightman RM, Carelli RM. Subsecond dopamine release promotes cocaine seeking. Nature. 422: 614-8. PMID 12687000 DOI: 10.1038/nature01476  0.855
2003 Venton BJ, Michael DJ, Wightman RM. Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate-putamen. Journal of Neurochemistry. 84: 373-81. PMID 12558999 DOI: 10.1046/J.1471-4159.2003.01527.X  0.808
2003 Phillips PE, Johns JM, Lubin DA, Budygin EA, Gainetdinov RR, Lieberman JA, Wightman RM. Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine. Brain Research. 961: 63-72. PMID 12535777 DOI: 10.1016/S0006-8993(02)03840-4  0.833
2003 Phillips PE, Robinson DL, Stuber GD, Carelli RM, Wightman RM. Real-time measurements of phasic changes in extracellular dopamine concentration in freely moving rats by fast-scan cyclic voltammetry. Methods in Molecular Medicine. 79: 443-64. PMID 12506716 DOI: 10.1385/1-59259-358-5:443  0.837
2003 Venton BJ, Wightman RM. Psychoanalytical electrochemistry: Dopamine and behavior Analytical Chemistry. 75: 414A-421A. DOI: 10.1021/Ac031421C  0.755
2002 Mundroff ML, Wightman RM. Amperometry and cyclic voltammetry with carbon fiber microelectrodes at single cells. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.14. PMID 18428562 DOI: 10.1002/0471142301.Ns0614S18  0.34
2002 Robinson DL, Heien ML, Wightman RM. Frequency of dopamine concentration transients increases in dorsal and ventral striatum of male rats during introduction of conspecifics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10477-86. PMID 12451147 DOI: 10.1523/Jneurosci.22-23-10477.2002  0.835
2002 Wightman RM, Troyer KP, Mundorf ML, Catahan R. The association of vesicular contents and its effects on release. Annals of the New York Academy of Sciences. 971: 620-6. PMID 12438196 DOI: 10.1111/J.1749-6632.2002.Tb04540.X  0.806
2002 Troyer KP, Mundorf ML, Fries HE, Wightman RM. Separating vesicle fusion and exocytosis in hypertonic conditions. Annals of the New York Academy of Sciences. 971: 251-3. PMID 12438126 DOI: 10.1111/J.1749-6632.2002.Tb04470.X  0.801
2002 Troyer KP, Heien ML, Venton BJ, Wightman RM. Neurochemistry and electroanalytical probes. Current Opinion in Chemical Biology. 6: 696-703. PMID 12413556 DOI: 10.1016/S1367-5931(02)00374-5  0.802
2002 Troyer KP, Wightman RM. Dopamine transport into a single cell in a picoliter vial. Analytical Chemistry. 74: 5370-5. PMID 12403595 DOI: 10.1021/Ac0203903  0.841
2002 Wightman RM, Robinson DL. Transient changes in mesolimbic dopamine and their association with 'reward'. Journal of Neurochemistry. 82: 721-35. PMID 12358778 DOI: 10.1046/j.1471-4159.2002.01005.x  0.771
2002 Joseph JD, Wang YM, Miles PR, Budygin EA, Picetti R, Gainetdinov RR, Caron MG, Wightman RM. Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. Neuroscience. 112: 39-49. PMID 12044470 DOI: 10.1016/S0306-4522(02)00067-2  0.848
2002 Troyer KP, Wightman RM. Temporal separation of vesicle release from vesicle fusion during exocytosis. The Journal of Biological Chemistry. 277: 29101-7. PMID 12034731 DOI: 10.1074/Jbc.M202856200  0.807
2002 Mottola DM, Kilts JD, Lewis MM, Connery HS, Walker QD, Jones SR, Booth RG, Hyslop DK, Piercey M, Wightman RM, Lawler CP, Nichols DE, Mailman RB. Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase. The Journal of Pharmacology and Experimental Therapeutics. 301: 1166-78. PMID 12023552 DOI: 10.1124/jpet.301.3.1166  0.59
2002 Miles PR, Mundorf ML, Wightman RM. Release and uptake of catecholamines in the bed nucleus of the stria terminalis measured in the mouse brain slice. Synapse (New York, N.Y.). 44: 188-97. PMID 11954051 DOI: 10.1002/Syn.10069  0.82
2002 Venton BJ, Troyer KP, Wightman RM. Response times of carbon fiber microelectrodes to dynamic changes in catecholamine concentration. Analytical Chemistry. 74: 539-46. PMID 11838672 DOI: 10.1021/Ac010819A  0.843
2002 Gross EM, Armstrong NR, Wightman RM. Electrogenerated chemiluminescence from phosphorescent molecules used in organic light-emitting diodes Journal of the Electrochemical Society. 149: E137-E142. DOI: 10.1149/1.1464137  0.501
2002 Slaterbeck AF, Meehan TD, Gross EM, Wightman RM. Selective population of excited states during electrogenerated chemiluminescence with 10-methylphenothiazine Journal of Physical Chemistry B. 106: 6088-6095. DOI: 10.1021/Jp0127824  0.547
2001 Wu Q, Reith ME, Wightman RM, Kawagoe KT, Garris PA. Determination of release and uptake parameters from electrically evoked dopamine dynamics measured by real-time voltammetry. Journal of Neuroscience Methods. 112: 119-33. PMID 11716947 DOI: 10.1016/S0165-0270(01)00459-9  0.803
2001 Mundorf ML, Joseph JD, Austin CM, Caron MG, Wightman RM. Catecholamine release and uptake in the mouse prefrontal cortex. Journal of Neurochemistry. 79: 130-42. PMID 11595765 DOI: 10.1046/J.1471-4159.2001.00554.X  0.83
2001 Budygin EA, Phillips PE, Wightman RM, Jones SR. Terminal effects of ethanol on dopamine dynamics in rat nucleus accumbens: an in vitro voltammetric study. Synapse (New York, N.Y.). 42: 77-9. PMID 11574942 DOI: 10.1002/syn.1101  0.839
2001 Maus RG, Wightman RM. Microscopic imaging with electrogenerated chemiluminescence. Analytical Chemistry. 73: 3993-8. PMID 11534727 DOI: 10.1021/ac010128e  0.775
2001 Robinson DL, Phillips PE, Budygin EA, Trafton BJ, Garris PA, Wightman RM. Sub-second changes in accumbal dopamine during sexual behavior in male rats. Neuroreport. 12: 2549-52. PMID 11496146 DOI: 10.1097/00001756-200108080-00051  0.854
2001 Puopolo M, Hochstetler SE, Gustincich S, Wightman RM, Raviola E. Extrasynaptic release of dopamine in a retinal neuron: activity dependence and transmitter modulation. Neuron. 30: 211-25. PMID 11343656 DOI: 10.1016/S0896-6273(01)00274-4  0.49
2001 Armstrong NR, Wightman RM, Gross EM. Light-emitting electrochemical processes. Annual Review of Physical Chemistry. 52: 391-422. PMID 11326070 DOI: 10.1146/Annurev.Physchem.52.1.391  0.555
2001 Budygin EA, Phillips PE, Robinson DL, Kennedy AP, Gainetdinov RR, Wightman RM. Effect of acute ethanol on striatal dopamine neurotransmission in ambulatory rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 27-34. PMID 11259524  0.854
2001 Bath BD, Martin HB, Wightman RM, Anderson MR. Dopamine adsorption at surface modified carbon-fiber electrodes Langmuir. 17: 7032-7039. DOI: 10.1021/La0106844  0.389
2001 Gross EM, Pastore P, Wightman RM. High-frequency electrochemiluminescent investigation of the reaction pathway between tris(2,2′-bipyridyl)ruthenium(II) and tripropylamine using carbon fiber microelectrodes Journal of Physical Chemistry B. 105: 8732-8738. DOI: 10.1021/Jp011434Z  0.573
2000 Bath BD, Michael DJ, Trafton BJ, Joseph JD, Runnels PL, Wightman RM. Subsecond adsorption and desorption of dopamine at carbon-fiber microelectrodes. Analytical Chemistry. 72: 5994-6002. PMID 11140768 DOI: 10.1021/Ac000849Y  0.831
2000 Amatore C, Bouret Y, Travis ER, Wightman RM. Interplay between membrane dynamics, diffusion and swelling pressure governs individual vesicular exocytotic events during release of adrenaline by chromaffin cells. Biochimie. 82: 481-96. PMID 10865134 DOI: 10.1016/S0300-9084(00)00213-3  0.322
2000 Logman MJ, Budygin EA, Gainetdinov RR, Wightman RM. Quantitation of in vivo measurements with carbon fiber microelectrodes. Journal of Neuroscience Methods. 95: 95-102. PMID 10752479 DOI: 10.1016/S0165-0270(99)00155-7  0.762
2000 Mundorf ML, Troyer KP, Hochstetler SE, Near JA, Wightman RM. Vesicular Ca(2+) participates in the catalysis of exocytosis. The Journal of Biological Chemistry. 275: 9136-42. PMID 10734047 DOI: 10.1074/Jbc.275.13.9136  0.79
2000 Kilpatrick MR, Rooney MB, Michael DJ, Wightman RM. Extracellular dopamine dynamics in rat caudate-putamen during experimenter-delivered and intracranial self-stimulation. Neuroscience. 96: 697-706. PMID 10727788 DOI: 10.1016/S0306-4522(99)00578-3  0.861
2000 Hochstetler SE, Puopolo M, Gustincich S, Raviola E, Wightman RM. Real-time amperometric measurements of zeptomole quantities of dopamine released from neurons. Analytical Chemistry. 72: 489-96. PMID 10695133 DOI: 10.1021/Ac991119X  0.527
2000 Budygin EA, Kilpatrick MR, Gainetdinov RR, Wightman RM. Correlation between behavior and extracellular dopamine levels in rat striatum: comparison of microdialysis and fast-scan cyclic voltammetry. Neuroscience Letters. 281: 9-12. PMID 10686403 DOI: 10.1016/S0304-3940(00)00813-2  0.851
2000 Walker QD, Rooney MB, Wightman RM, Kuhn CM. Dopamine release and uptake are greater in female than male rat striatum as measured by fast cyclic voltammetry. Neuroscience. 95: 1061-70. PMID 10682713 DOI: 10.1016/S0306-4522(99)00500-X  0.435
2000 Travis ER, Wang YM, Michael DJ, Caron MG, Wightman RM. Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 162-7. PMID 10618388 DOI: 10.1073/Pnas.97.1.162  0.754
2000 Gross EM, Anderson JD, Slaterbeck AF, Thayumanavan S, Barlow S, Zhang Y, Marder SR, Hall HK, Flore Nabor M, Wang JF, Mash EA, Armstrong NR, Wightman RM. Electrogenerated chemiluminescence from derivatives of aluminum quinolate and quinacridones: Cross-reactions with triarylamines lead to singlet emission through triplet-triplet annihilation pathways Journal of the American Chemical Society. 122: 4972-4979. DOI: 10.1021/Ja0005993  0.512
1999 Maus RG, McDonald EM, Wightman RM. Imaging of nonuniform current density at microelectrodes by electrogenerated chemiluminescence. Analytical Chemistry. 71: 4944-50. PMID 21662840 DOI: 10.1021/Ac9905827  0.778
1999 Michael DJ, Wightman RM. Electrochemical monitoring of biogenic amine neurotransmission in real time. Journal of Pharmaceutical and Biomedical Analysis. 19: 33-46. PMID 10698566 DOI: 10.1016/S0731-7085(98)00145-9  0.69
1999 Jones SR, Joseph JD, Barak LS, Caron MG, Wightman RM. Dopamine neuronal transport kinetics and effects of amphetamine. Journal of Neurochemistry. 73: 2406-14. PMID 10582600 DOI: 10.1046/J.1471-4159.1999.0732406.X  0.842
1999 Mundorf ML, Hochstetler SE, Wightman RM. Amine weak bases disrupt vesicular storage and promote exocytosis in chromaffin cells. Journal of Neurochemistry. 73: 2397-405. PMID 10582599 DOI: 10.1046/J.1471-4159.1999.0732397.X  0.781
1999 Budygin EA, Kilpatrick M, Ga?netdinov RR, Raevski? KS, Wightman RM. [The effect of the dopamine neuronal reuptake inhibitor GBR 12909 on the dopaminergic neurotransmission parameters in the rat striatum in vivo]. Eksperimental'Naia I Klinicheskaia Farmakologiia. 62: 3-6. PMID 10572741  0.853
1999 Michael DJ, Joseph JD, Kilpatrick MR, Travis ER, Wightman RM. Improving data acquisition for fast-scan cyclic voltammetry. Analytical Chemistry. 71: 3941-7. PMID 10500480 DOI: 10.1021/Ac990491+  0.804
1999 Runnels PL, Joseph JD, Logman MJ, Wightman RM. Effect of pH and surface functionalities on the cyclic voltammetric responses of carbon-fiber microelectrodes. Analytical Chemistry. 71: 2782-9. PMID 10424168 DOI: 10.1021/ac981279t  0.695
1999 Jones SR, Gainetdinov RR, Hu XT, Cooper DC, Wightman RM, White FJ, Caron MG. Loss of autoreceptor functions in mice lacking the dopamine transporter. Nature Neuroscience. 2: 649-55. PMID 10404198 DOI: 10.1038/10204  0.757
1999 Budygin EA, Gainetdinov RR, Kilpatrick MR, Rayevsky KS, Männistö PT, Wightman RM. Effect of tolcapone, a catechol-O-methyltransferase inhibitor, on striatal dopaminergic transmission during blockade of dopamine uptake. European Journal of Pharmacology. 370: 125-31. PMID 10323260 DOI: 10.1016/S0014-2999(99)00084-9  0.858
1999 Garris PA, Kilpatrick M, Bunin MA, Michael D, Walker QD, Wightman RM. Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation. Nature. 398: 67-9. PMID 10078530 DOI: 10.1038/18019  0.86
1999 Wightman RM, Runnels P, Troyer K. Analysis of chemical dynamics in microenvironments Analytica Chimica Acta. 400: 5-12. DOI: 10.1016/S0003-2670(99)00605-4  0.78
1998 Michael D, Travis ER, Wightman RM. Color images for fast-scan CV measurements in biological systems. Analytical Chemistry. 70: 586A-592A. PMID 9737201 DOI: 10.1021/Ac9819640  0.667
1998 Gainetdinov RR, Jones SR, Fumagalli F, Wightman RM, Caron MG. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain Research. Brain Research Reviews. 26: 148-53. PMID 9651511 DOI: 10.1016/S0165-0173(97)00063-5  0.764
1998 Travis ER, Wightman RM. Spatio-temporal resolution of exocytosis from individual cells. Annual Review of Biophysics and Biomolecular Structure. 27: 77-103. PMID 9646863 DOI: 10.1146/annurev.biophys.27.1.77  0.349
1998 Bunin MA, Wightman RM. Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: an investigation of extrasynaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4854-60. PMID 9634551 DOI: 10.1523/Jneurosci.18-13-04854.1998  0.361
1998 Xin Q, Wightman RM. Simultaneous detection of catecholamine exocytosis and Ca2+ release from single bovine chromaffin cells using a dual microsensor. Analytical Chemistry. 70: 1677-81. PMID 9599575 DOI: 10.1021/Ac970746O  0.317
1998 Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 4029-34. PMID 9520487 DOI: 10.1073/Pnas.95.7.4029  0.773
1998 Bunin MA, Prioleau C, Mailman RB, Wightman RM. Release and uptake rates of 5-hydroxytryptamine in the dorsal raphe and substantia nigra reticulata of the rat brain. Journal of Neurochemistry. 70: 1077-87. PMID 9489728 DOI: 10.1046/J.1471-4159.1998.70031077.X  0.401
1998 Jones SR, Gainetdinov RR, Wightman RM, Caron MG. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1979-86. PMID 9482784 DOI: 10.1523/Jneurosci.18-06-01979.1998  0.766
1998 Pihel K, Hsieh S, Jorgenson JW, Wightman RM. Quantal corelease of histamine and 5-hydroxytryptamine from mast cells and the effects of prior incubation. Biochemistry. 37: 1046-52. PMID 9454595 DOI: 10.1021/Bi9714868  0.541
1998 Fumagalli F, Jones S, Bossé R, Jaber M, Giros B, Missale C, Wightman RM, Caron MG. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. Advances in Pharmacology (San Diego, Calif.). 42: 179-82. PMID 9327873 DOI: 10.1016/S1054-3589(08)60722-X  0.73
1998 Mickelson GE, Garris PA, Bunin M, Wightman RM. In vivo and in vitro assessment of dopamine uptake and release. Advances in Pharmacology (San Diego, Calif.). 42: 144-7. PMID 9327867 DOI: 10.1016/S1054-3589(08)60716-4  0.718
1997 Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron. 19: 1285-96. PMID 9427251 DOI: 10.1016/S0896-6273(00)80419-5  0.767
1997 Garris PA, Walker QD, Wightman RM. Dopamine release and uptake rates both decrease in the partially denervated striatum in proportion to the loss of dopamine terminals. Brain Research. 753: 225-34. PMID 9125407 DOI: 10.1016/S0006-8993(97)00003-6  0.762
1997 Borges R, Travis ER, Hochstetler SE, Wightman RM. Effects of external osmotic pressure on vesicular secretion from bovine adrenal medullary cells. The Journal of Biological Chemistry. 272: 8325-31. PMID 9079655 DOI: 10.1074/jbc.272.13.8325  0.308
1997 Garris PA, Christensen JR, Rebec GV, Wightman RM. Real-time measurement of electrically evoked extracellular dopamine in the striatum of freely moving rats. Journal of Neurochemistry. 68: 152-61. PMID 8978721 DOI: 10.1046/J.1471-4159.1997.68010152.X  0.778
1997 Maness KM, Masui H, Wightman RM, Murray RW. Solid State Electrochemically Generated Luminescence Based on Serial Frozen Concentration Gradients of RuIII/IIand RuII/ICouples in a Molten Ruthenium 2,2‘-Bipyridine Complex Journal of the American Chemical Society. 119: 3987-3993. DOI: 10.1021/JA9636754  0.529
1997 Xin Q, Wightman RM. Enzyme modified amperometric sensors for choline and acetylcholine with tetrathiafulvalene tetracyanoquinodimethane as the electron-transfer mediator Analytica Chimica Acta. 341: 43-51. DOI: 10.1016/S0003-2670(96)00492-8  0.338
1996 Pihel K, Walker QD, Wightman RM. Overoxidized polypyrrole-coated carbon fiber microelectrodes for dopamine measurements with fast-scan cyclic voltammetry. Analytical Chemistry. 68: 2084-9. PMID 9027223 DOI: 10.1021/Ac960153Y  0.429
1996 Jones SR, Bowman BP, Kuhn CM, Wightman RM. Development of dopamine neurotransmission and uptake inhibition in the caudate nucleus as measured by fast-cyclic voltammetry. Synapse (New York, N.Y.). 24: 305-7. PMID 8923671 DOI: 10.1002/(SICI)1098-2396(199611)24:3<305::AID-SYN13>3.0.CO;2-V  0.709
1996 Jones SR, Lee TH, Wightman RM, Ellinwood EH. Effects of intermittent and continuous cocaine administration on dopamine release and uptake regulation in the striatum: in vitro voltammetric assessment. Psychopharmacology. 126: 331-8. PMID 8878349 DOI: 10.1007/Bf02247384  0.654
1996 Jones SR, O'Dell SJ, Marshall JF, Wightman RM. Functional and anatomical evidence for different dopamine dynamics in the core and shell of the nucleus accumbens in slices of rat brain. Synapse (New York, N.Y.). 23: 224-31. PMID 8807751 DOI: 10.1002/(SICI)1098-2396(199607)23:3<224::AID-SYN12>3.0.CO;2-Z  0.721
1996 Cahill PS, Walker QD, Finnegan JM, Mickelson GE, Travis ER, Wightman RM. Microelectrodes for the measurement of catecholamines in biological systems. Analytical Chemistry. 68: 3180-6. PMID 8797378 DOI: 10.1021/Ac960347D  0.403
1996 Finnegan JM, Pihel K, Cahill PS, Huang L, Zerby SE, Ewing AG, Kennedy RT, Wightman RM. Vesicular quantal size measured by amperometry at chromaffin, mast, pheochromocytoma, and pancreatic beta-cells. Journal of Neurochemistry. 66: 1914-23. PMID 8780018 DOI: 10.1046/J.1471-4159.1996.66051914.X  0.723
1996 Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379: 606-12. PMID 8628395 DOI: 10.1038/379606A0  0.722
1996 Maness KM, Terrill RH, Meyer TJ, Murray RW, Wightman RM. Solid-State Diode-like Chemiluminescence Based on Serial, Immobilized Concentration Gradients in Mixed-Valent Poly[Ru(vbpy)3](PF6)2Films Journal of the American Chemical Society. 118: 10609-10616. DOI: 10.1021/Ja953185W  0.454
1995 Cahill PS, Wightman RM. Simultaneous amperometric measurement of ascorbate and catecholamine secretion from individual bovine adrenal medullary cells. Analytical Chemistry. 67: 2599-605. PMID 8849026 DOI: 10.1021/Ac00111A017  0.387
1995 Pihel K, Hsieh S, Jorgenson JW, Wightman RM. Electrochemical detection of histamine and 5-hydroxytryptamine at isolated mast cells. Analytical Chemistry. 67: 4514-21. PMID 8633786 DOI: 10.1021/Ac00120A014  0.505
1995 Jackson BP, Wightman RM. Dynamics of 5-hydroxytryptamine released from dopamine neurons in the caudate putamen of the rat. Brain Research. 674: 163-6. PMID 7773688 DOI: 10.1016/0006-8993(95)00019-M  0.449
1995 Jones SR, Garris PA, Kilts CD, Wightman RM. Comparison of dopamine uptake in the basolateral amygdaloid nucleus, caudate-putamen, and nucleus accumbens of the rat. Journal of Neurochemistry. 64: 2581-9. PMID 7760038 DOI: 10.1046/J.1471-4159.1995.64062581.X  0.812
1995 Jones SR, Garris PA, Wightman RM. Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 274: 396-403. PMID 7616424  0.798
1995 Garris PA, Wightman RM. Distinct pharmacological regulation of evoked dopamine efflux in the amygdala and striatum of the rat in vivo. Synapse (New York, N.Y.). 20: 269-79. PMID 7570359 DOI: 10.1002/syn.890200311  0.747
1994 Kawagoe KT, Wightman RM. Characterization of amperometry for in vivo measurement of dopamine dynamics in the rat brain. Talanta. 41: 865-74. PMID 18966011 DOI: 10.1016/0039-9140(94)E0064-X  0.668
1994 Garris PA, Wightman RM. Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex, and striatum: an in vivo voltammetric study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 442-50. PMID 8283249  0.726
1994 Jones SR, Mickelson GE, Collins LB, Kawagoe KT, Wightman RM. Interference by pH and Ca2+ ions during measurements of catecholamine release in slices of rat amygdala with fast-scan cyclic voltammetry. Journal of Neuroscience Methods. 52: 1-10. PMID 8090011 DOI: 10.1016/0165-0270(94)90048-5  0.74
1994 Cooper BR, Wightman RM, Jorgenson JW. Quantitation of epinephrine and norepinephrine secretion from individual adrenal medullary cells by microcolumn high-performance liquid chromatography. Journal of Chromatography. B, Biomedical Applications. 653: 25-34. PMID 8012556 DOI: 10.1016/0378-4347(93)E0423-N  0.525
1994 Garris PA, Ciolkowski EL, Wightman RM. Heterogeneity of evoked dopamine overflow within the striatal and striatoamygdaloid regions. Neuroscience. 59: 417-27. PMID 8008199 DOI: 10.1016/0306-4522(94)90606-8  0.737
1994 Garris PA, Wightman RM. In vivo voltammetric measurement of evoked extracellular dopamine in the rat basolateral amygdaloid nucleus. The Journal of Physiology. 478: 239-49. PMID 7965845  0.749
1994 Garris PA, Ciolkowski EL, Pastore P, Wightman RM. Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6084-93. PMID 7931564  0.731
1993 Capella P, Ghasemzadeh MB, Adams RN, Wiedemann DJ, Wightman RM. Real-time monitoring of electrically stimulated norepinephrine release in rat thalamus: II. Modeling of release and reuptake characteristics of stimulated norepinephrine overflow. Journal of Neurochemistry. 60: 449-53. PMID 8419531 DOI: 10.1111/J.1471-4159.1993.Tb03171.X  0.679
1993 Kawagoe KT, Zimmerman JB, Wightman RM. Principles of voltammetry and microelectrode surface states. Journal of Neuroscience Methods. 48: 225-40. PMID 8412305 DOI: 10.1016/0165-0270(93)90094-8  0.547
1993 Garris PA, Collins LB, Jones SR, Wightman RM. Evoked extracellular dopamine in vivo in the medial prefrontal cortex. Journal of Neurochemistry. 61: 637-47. PMID 8336146 DOI: 10.1111/J.1471-4159.1993.Tb02168.X  0.82
1993 Kawagoe KT, Garris PA, Wightman R. pH-Dependent processes at Nafion®-coated carbon-fiber microelectrodes Journal of Electroanalytical Chemistry. 359: 193-207. DOI: 10.1016/0022-0728(93)80409-B  0.665
1992 Zimmerman JB, Kennedy RT, Wightman RM. Evoked neuronal activity accompanied by transmitter release increases oxygen concentration in rat striatum in vivo but not in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 629-37. PMID 1618942 DOI: 10.1038/Jcbfm.1992.87  0.711
1992 Cooper BR, Jankowski JA, Leszczyszyn DJ, Wightman RM, Jorgenson JW. Quantitative determination of catecholamines in individual bovine adrenomedullary cells by reversed-phase microcolumn liquid chromatography with electrochemical detection. Analytical Chemistry. 64: 691-4. PMID 1580362 DOI: 10.1021/Ac00030A022  0.51
1992 Wiedemann DJ, Garris PA, Near JA, Wightman RM. Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. The Journal of Pharmacology and Experimental Therapeutics. 261: 574-9. PMID 1533666  0.711
1992 Schroeder TJ, Jankowski JA, Kawagoe KT, Wightman RM, Lefrou C, Amatore C. Analysis of diffusional broadening of vesicular packets of catecholamines released from biological cells during exocytosis. Analytical Chemistry. 64: 3077-83. PMID 1492662 DOI: 10.1021/Ac00048A003  0.5
1992 Kawagoe KT, Garris PA, Wiedemann DJ, Wightman RM. Regulation of transient dopamine concentration gradients in the microenvironment surrounding nerve terminals in the rat striatum. Neuroscience. 51: 55-64. PMID 1465186 DOI: 10.1016/0306-4522(92)90470-M  0.806
1992 Kennedy RT, Jones SR, Wightman RM. Dynamic observation of dopamine autoreceptor effects in rat striatal slices. Journal of Neurochemistry. 59: 449-55. PMID 1352798 DOI: 10.1111/J.1471-4159.1992.Tb09391.X  0.783
1992 Kennedy RT, Jones SR, Wightman RM. Simultaneous measurement of oxygen and dopamine: coupling of oxygen consumption and neurotransmission. Neuroscience. 47: 603-12. PMID 1316568 DOI: 10.1016/0306-4522(92)90169-3  0.767
1992 Ciolkowski EL, Cooper BR, Jankowski JA, Jorgenson JW, Wightman RM. Direct observation of epinephrine and norepinephrine cosecretion from individual adrenal medullary chromaffin cells Journal of the American Chemical Society. 114: 2815-2821. DOI: 10.1021/Ja00034A009  0.522
1991 Leszczyszyn DJ, Jankowski JA, Viveros OH, Diliberto EJ, Near JA, Wightman RM. Secretion of catecholamines from individual adrenal medullary chromaffin cells. Journal of Neurochemistry. 56: 1855-63. PMID 2027003 DOI: 10.1111/J.1471-4159.1991.Tb03441.X  0.346
1991 Wightman RM, Jankowski JA, Kennedy RT, Kawagoe KT, Schroeder TJ, Leszczyszyn DJ, Near JA, Diliberto EJ, Viveros OH. Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10754-8. PMID 1961743 DOI: 10.1073/Pnas.88.23.10754  0.721
1991 Kawagoe KT, Jankowski JA, Wightman RM. Etched carbon-fiber electrodes as amperometric detectors of catecholamine secretion from isolated biological cells. Analytical Chemistry. 63: 1589-94. PMID 1952084 DOI: 10.1021/Ac00015A017  0.545
1991 Zimmerman JB, Wightman RM. Simultaneous electrochemical measurements of oxygen and dopamine in vivo. Analytical Chemistry. 63: 24-8. PMID 1810167  0.319
1991 Wiedemann DJ, Kawagoe KT, Kennedy RT, Ciolkowski EL, Wightman RM. Strategies for low detection limit measurements with cyclic voltammetry. Analytical Chemistry. 63: 2965-70. PMID 1789456 DOI: 10.1021/Ac00024A030  0.701
1990 Wightman RM, Zimmerman JB. Control of dopamine extracellular concentration in rat striatum by impulse flow and uptake. Brain Research. Brain Research Reviews. 15: 135-44. PMID 2282449 DOI: 10.1016/0165-0173(90)90015-G  0.407
1990 Wiedemann DJ, Basse-Tomusk A, Wilson RL, Rebec GV, Wightman RM. Interference by DOPAC and ascorbate during attempts to measure drug-induced changes in neostriatal dopamine with Nafion-coated, carbon-fiber electrodes. Journal of Neuroscience Methods. 35: 9-18. PMID 2148961 DOI: 10.1016/0165-0270(90)90089-X  0.547
1990 Wightman RM, Wipf DO. High-speed cyclic voltammetry Accounts of Chemical Research. 23: 64-70. DOI: 10.1021/Ar00171A002  0.611
1990 Wipf DO, Wightman RM. Voltammetry with microvoltammetric electrodes in resistive solvents under linear diffusion conditions Analytical Chemistry. 62: 98-102. DOI: 10.1021/Ac00201A002  0.627
1989 May LJ, Wightman RM. Heterogeneity of stimulated dopamine overflow within rat striatum as observed with in vivo voltammetry. Brain Research. 487: 311-20. PMID 2786444 DOI: 10.1016/0006-8993(89)90835-4  0.508
1989 May LJ, Wightman RM. Effects of D-2 antagonists on frequency-dependent stimulated dopamine overflow in nucleus accumbens and caudate-putamen. Journal of Neurochemistry. 53: 898-906. PMID 2527290  0.459
1989 Wipf DO, Wightman RM. Rapid cleavage reactions of haloaromatic radical anions measured with fast-scan cyclic voltammetry Journal of Physical Chemistry®. 93: 4286-4291. DOI: 10.1021/J100347A074  0.637
1989 Stamford JA, Hurst PR, Kuhr WG, Wightman RM. Characterization of rates of adsorption with fast-scan cyclic voltammetry Journal of Electroanalytical Chemistry. 265: 291-296. DOI: 10.1016/0022-0728(89)80197-4  0.617
1989 Wipf DO, Michael AC, Wightman RM. Microdisk electrodes. Part II. Fast-scan cyclic voltammetry with very small electrodes Journal of Electroanalytical Chemistry. 269: 15-25. DOI: 10.1016/0022-0728(89)80100-7  0.601
1988 Wightman RM, Amatore C, Engstrom RC, Hale PD, Kristensen EW, Kuhr WG, May LJ. Real-time characterization of dopamine overflow and uptake in the rat striatum. Neuroscience. 25: 513-23. PMID 3399057 DOI: 10.1016/0306-4522(88)90255-2  0.455
1988 Near JA, Bigelow JC, Wightman RM. Comparison of uptake of dopamine in rat striatal chopped tissue and synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 245: 921-7. PMID 3385647  0.323
1988 Keller RW, Kuhr WG, Wightman RM, Zigmond MJ. The effect of L-dopa on in vivo dopamine release from nigrostriatal bundle neurons. Brain Research. 447: 191-4. PMID 3382951 DOI: 10.1016/0006-8993(88)90985-7  0.482
1988 Kristensen EW, Bigelow JC, Wightman RM. Time resolved dopamine overflow from synaptosomes and chopped striatal tissue with rapid superfusion. Brain Research. 461: 44-52. PMID 3224276 DOI: 10.1016/0006-8993(88)90723-8  0.492
1988 Wightman RM, May LJ, Michael AC. Detection of dopamine dynamics in the brain. Analytical Chemistry. 60: 769A-779A. PMID 3063135 DOI: 10.1021/ac00164a001  0.44
1988 May LJ, Kuhr WG, Wightman RM. Differentiation of dopamine overflow and uptake processes in the extracellular fluid of the rat caudate nucleus with fast-scan in vivo voltammetry. Journal of Neurochemistry. 51: 1060-9. PMID 2971098 DOI: 10.1111/j.1471-4159.1988.tb03069.x  0.401
1988 Wipf DO, Wightman RM. Submicrosecond measurements with cyclic voltammetry Analytical Chemistry. 60: 2460-2464. DOI: 10.1021/Ac00173A005  0.611
1988 Wipf DO, Kristensen EW, Deakin MR, Wightman RM. Fast-scan cyclic voltammetry as a method to measure rapid heterogeneous electron-transfer kinetics Analytical Chemistry. 60: 306-310. DOI: 10.1021/Ac00155A006  0.616
1987 Kelly RS, Wightman RM. Detection of dopamine overflow and diffusion with voltammetry in slices of rat brain. Brain Research. 423: 79-87. PMID 3676822 DOI: 10.1016/0006-8993(87)90827-4  0.556
1987 Kuhr WG, Wightman RM, Rebec GV. Dopaminergic neurons: simultaneous measurements of dopamine release and single-unit activity during stimulation of the medial forebrain bundle. Brain Research. 418: 122-8. PMID 3499205 DOI: 10.1016/0006-8993(87)90968-1  0.488
1987 Amatore C, Deakin MR, Wightman RM. Electrochemical kinetics at microelectrodes. Part IV. Electrochemistry in media of low ionic strength Journal of Electroanalytical Chemistry. 225: 49-63. DOI: 10.1016/0022-0728(87)80004-9  0.306
1987 WIPF DO, WEHMEYER KR, WIGHTMAN RM. ChemInform Abstract: Disproportionation of Quinone Radical Anions in Protic Solvents at High pH. Cheminform. 18. DOI: 10.1002/CHIN.198729058  0.562
1986 Wilson RL, Kamata K, Wightman RM, Rebec GV. Unilateral, intranigral infusions of amphetamine produce differential, bilateral changes in unit activity and extracellular levels of ascorbate in the neostriatum of the rat. Brain Research. 384: 342-7. PMID 3779385 DOI: 10.1016/0006-8993(86)91170-4  0.399
1986 Wightman RM, Kuhr WG, Ewing AG. Voltammetric detection of dopamine release in the rat corpus striatum. Annals of the New York Academy of Sciences. 473: 92-105. PMID 3541742 DOI: 10.1111/J.1749-6632.1986.Tb23607.X  0.739
1986 Wilson RL, Kamata K, Bigelow JC, Rebec GV, Wightman RM. Crus cerebri lesions abolish amphetamine-induced ascorbate release in the rat neostriatum. Brain Research. 370: 393-6. PMID 3518863 DOI: 10.1016/0006-8993(86)90501-9  0.452
1986 Kuhr WG, Wightman RM. Real-time measurement of dopamine release in rat brain. Brain Research. 381: 168-71. PMID 3489505 DOI: 10.1016/0006-8993(86)90707-9  0.505
1986 Kuhr WG, Bigelow JC, Wightman RM. In vivo comparison of the regulation of releasable dopamine in the caudate nucleus and the nucleus accumbens of the rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 974-82. PMID 3486259  0.473
1986 Wipf DO, Wehmeyer KR, Wightman RM. Disproportionation of quinone radical anions in protic solvents at high pH The Journal of Organic Chemistry. 51: 4760-4764. DOI: 10.1021/Jo00375A003  0.589
1986 Kelly RS, Wightman RM. Bevelled carbon-fiber ultramicroelectrodes Analytica Chimica Acta. 187: 79-87. DOI: 10.1016/S0003-2670(00)82900-1  0.3
1986 Johnson DC, Weber SG, Bond AM, Wightman RM, Shoup RE, Krull IS. Electroanalytical voltammetry in flowing solutions Analytica Chimica Acta. 180: 187-250. DOI: 10.1016/0003-2670(86)80007-1  0.402
1985 Wilson RL, Wightman RM. Systemic and nigral application of amphetamine both cause an increase in extracellular concentration of ascorbate in the caudate nucleus of the rat. Brain Research. 339: 219-26. PMID 4027622 DOI: 10.1016/0006-8993(85)90086-1  0.499
1985 Caudill WL, Bigelow JC, Wightman RM. Comparison of release of endogenous dopamine and gamma-aminobutyric acid from rat caudate synaptosomes. Neurochemical Research. 10: 319-31. PMID 4000390 DOI: 10.1007/Bf00964602  0.462
1985 Kuhr WG, Ewing AG, Near JA, Wightman RM. Amphetamine attenuates the stimulated release of dopamine in vivo. The Journal of Pharmacology and Experimental Therapeutics. 232: 388-94. PMID 3968641  0.741
1985 Millar J, Stamford JA, Kruk ZL, Wightman RM. Electrochemical, pharmacological and electrophysiological evidence of rapid dopamine release and removal in the rat caudate nucleus following electrical stimulation of the median forebrain bundle. European Journal of Pharmacology. 109: 341-8. PMID 3872803 DOI: 10.1016/0014-2999(85)90394-2  0.746
1985 Gardiner TW, Armstrong-James M, Caan AW, Wightman RM, Rebec GV. Modulation of neostriatal activity by iontophoresis of ascorbic acid. Brain Research. 344: 181-5. PMID 2864108 DOI: 10.1016/0006-8993(85)91207-7  0.302
1984 Kovach PM, Ewing AG, Wilson RL, Wightman RM. In vitro comparison of the selectivity of electrodes for in vivo electrochemistry. Journal of Neuroscience Methods. 10: 215-27. PMID 6738110 DOI: 10.1016/0165-0270(84)90058-X  0.624
1984 Ewing AG, Wightman RM. Monitoring the stimulated release of dopamine with in vivo voltammetry. II: Clearance of released dopamine from extracellular fluid. Journal of Neurochemistry. 43: 570-7. PMID 6736966 DOI: 10.1111/J.1471-4159.1984.Tb00936.X  0.764
1984 Kuhr WG, Ewing AG, Caudill WL, Wightman RM. Monitoring the stimulated release of dopamine with in vivo voltammetry. I: Characterization of the response observed in the caudate nucleus of the rat. Journal of Neurochemistry. 43: 560-9. PMID 6736965 DOI: 10.1111/J.1471-4159.1984.Tb00935.X  0.769
1984 Stamford JA, Kruk ZL, Millar J, Wightman RM. Striatal dopamine uptake in the rat: in vivo analysis by fast cyclic voltammetry. Neuroscience Letters. 51: 133-8. PMID 6334821 DOI: 10.1016/0304-3940(84)90274-X  0.751
1983 Ewing AG, Bigelow JC, Wightman RM. Direct in vivo monitoring of dopamine released from two striatal compartments in the rat. Science (New York, N.Y.). 221: 169-71. PMID 6857277 DOI: 10.1126/Science.6857277  0.739
1983 Ewing AG, Alloway KD, Curtis SD, Dayton MA, Wightman RM, Rebec GV. Simultaneous electrochemical and unit recording measurements: characterization of the effects of D-amphetamine and ascorbic acid on neostriatal neurons. Brain Research. 261: 101-8. PMID 6301620 DOI: 10.1016/0006-8993(83)91288-X  0.685
1983 Caudill WL, Ewing AG, Jones S, Wightman RM. Liquid chromatography with rapid scanning electrochemical detection at carbon electrodes Analytical Chemistry. 55: 1877-1881. DOI: 10.1021/Ac00262A010  0.569
1983 Dayton MA, Ewing AG, Wightman RM. Diffusion processes measured at microvoltammetric electrodes in brain tissue Journal of Electroanalytical Chemistry and Interfacial Electrochemistry. 146: 189-200. DOI: 10.1016/S0022-0728(83)80121-1  0.609
1982 Caviness JN, Wightman RM. Use of rapid superfusion to differentiate the release of dopamine from striatal tissue induced by sympathomimetic amines from release induced by potassium. The Journal of Pharmacology and Experimental Therapeutics. 223: 90-6. PMID 7120132  0.382
1982 Ewing AG, Wightman RM, Dayton MA. In vivo voltammetry with electrodes that discriminate between dopamine and ascorbate. Brain Research. 249: 361-70. PMID 6814706 DOI: 10.1016/0006-8993(82)90070-1  0.717
1981 Dayton MA, Ewing AG, Wightman RM. Evaluation of amphetamine-induced in vivo electrochemical response. European Journal of Pharmacology. 75: 141-4. PMID 7318902 DOI: 10.1016/0014-2999(81)90074-1  0.751
1981 Wightman RM, Bright CE, Caviness JN. Direct measurement of the effect of potassium, calcium, veratridine, and amphetamine on the rate of release of dopamine from superfused brain tissue. Life Sciences. 28: 1279-86. PMID 7231050  0.355
1981 Ewing AG, Withnell R, Wightman RM. Instrument design for pulse voltammetry with microvoltammetric electrodes Review of Scientific Instruments. 52: 454-458. DOI: 10.1063/1.1136610  0.612
1981 Ewing AG, Dayton MA, Wightman RM. Pulse voltammetry with microvoltammetric electrodes Analytical Chemistry. 53: 1842-1847. DOI: 10.1021/Ac00235A028  0.55
1980 Dayton MA, Ewing AG, Wightman RM. Response of microvoltammetric electrodes to homogeneous catalytic and slow heterogeneous charge-transfer reactions Analytical Chemistry. 52: 2392-2396. DOI: 10.1021/Ac50064A035  0.591
1979 Dayton MA, Geier GE, Wightman RM. Electrochemical measurement of release of dopamine and 5-hydroxytryptamine from synaptosomes. Life Sciences. 24: 917-24. PMID 449600  0.453
1978 Wightman RM, Strope E, Plotsky P, Adams RN. In vivo voltammetry: monitoring of dopamine metabolites in CSF following release by electrical stimulation. Brain Research. 159: 55-68. PMID 728801 DOI: 10.1016/0006-8993(78)90109-9  0.634
1977 Wightman RM, Plotsky PM, Strope E, Delcore R, Adams RN. Liquid chromatographic monitoring of CSF metabolites. Brain Research. 131: 345-9. PMID 890461 DOI: 10.1016/0006-8993(77)90526-1  0.391
1977 Plotsky PM, Wightman RM, Chey W, Adams RN. Liquid chromatographic analysis of endogenous catecholamine release from brain slices. Science (New York, N.Y.). 197: 904-6. PMID 887928 DOI: 10.1126/Science.887928  0.503
1976 Blank CL, McCreery RL, Wightman RM, Chey W, Adams RN, Reid JR, Smissman EE. Intracyclization rates of 6-hydroxydopamine and 6-aminodopamine analogs under physiological conditions. Journal of Medicinal Chemistry. 19: 178-80. PMID 1246041 DOI: 10.1021/Jm00223A035  0.602
1976 Wightman RM, Strope E, Plotsky PM, Adams RN. Monitoring of transmitter metabolites by voltammetry in cerebrospinal fluid following neural pathway stimulation. Nature. 262: 145-6. PMID 934333 DOI: 10.1038/262145a0l  0.566
1976 Liang YO, Wightman RM, Adams RN. Competitive oxidation of 6-hydroxydopamine by oxygen and hydrogen peroxide. European Journal of Pharmacology. 36: 455-8. PMID 6288 DOI: 10.1016/0014-2999(76)90102-3  0.418
1976 Wightman RM, Cockrell JR, Murray RW, Burnett JN, Jones SB. Protonation kinetics and mechanism for 1,8-dihydroxyanthraquinone and anthraquinone anion radicals in dimethylformamide solvent Journal of the American Chemical Society. 98: 2562-2570. DOI: 10.1021/ja00425a027  0.435
1974 Wightman RM, Scott RL, Reilley CN, Murray RW, Kenan WR, Burnett JN. Computer controlled rapid scanning stop flow spectrometer Analytical Chemistry. 46: 1492-1499. DOI: 10.1021/Ac60347A027  0.45
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