Jenny P-Y Ting - Publications

University of North Carolina, Chapel Hill, Chapel Hill, NC 

243 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, Chen L, Montgomery ND, Li X, Bohannon LM, Sung AD, Chao NJ, Peled JU, Gomes ALC, van den Brink MRM, ... ... Ting JPY, et al. Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites. Science (New York, N.Y.). 370. PMID 33122357 DOI: 10.1126/science.aay9097  0.56
2020 Guo H, Gibson SA, Ting JPY. Gut microbiota, NLR proteins, and intestinal homeostasis. The Journal of Experimental Medicine. 217. PMID 32941596 DOI: 10.1084/jem.20181832  0.48
2019 Gharagozloo M, Mahmoud S, Simard C, Yamamoto K, Bobbala D, Ilangumaran S, Smith MD, Lamontagne A, Jarjoura S, Denault JB, Blais V, Gendron L, Vilariño-Güell C, Sadovnick AD, Ting JP, et al. NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity. Plos Biology. 17: e3000451. PMID 31525189 DOI: 10.1371/journal.pbio.3000451  0.52
2019 Mishima Y, Oka A, Liu B, Herzog JW, Eun CS, Fan TJ, Bulik-Sullivan E, Carroll IM, Hansen JJ, Chen L, Wilson JE, Fisher NC, Ting JPY, Nochi T, Wahl A, et al. Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells. The Journal of Clinical Investigation. 130. PMID 31211700 DOI: 10.1172/JCI93820  0.32
2018 Uchimura T, Oyama Y, Deng M, Guo H, Wilson JE, Rampanelli E, Cook KD, Misumi I, Tan X, Chen L, Johnson B, Tam J, Chou WC, Brickey WJ, Petrucelli A, ... ... Ting JPY, et al. The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity. Immunity. 49: 1049-1061.e6. PMID 30566882 DOI: 10.1016/j.immuni.2018.10.008  0.56
2017 Zhang S, Takaku M, Zou L, Gu AD, Chou WC, Zhang G, Wu B, Kong Q, Thomas SY, Serody JS, Chen X, Xu X, Wade PA, Cook DN, Ting JPY, et al. Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation. Nature. PMID 29072299 DOI: 10.1038/nature24283  0.36
2017 Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JP, Woosley JT, Blazar BR, Zaiss DM, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. The Journal of Clinical Investigation. PMID 28375154 DOI: 10.1172/JCI91816  0.4
2015 Kai MP, Brighton HE, Fromen CA, Shen TW, Luft JC, Luft YE, Keeler AW, Robbins GR, Ting JP, Zamboni WC, Bear JE, DeSimone JM. Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance. Acs Nano. PMID 26592524 DOI: 10.1021/acsnano.5b05999  0.4
2015 Liu R, Truax AD, Chen L, Hu P, Li Z, Chen J, Song C, Chen L, Ting JP. Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components. Oncotarget. PMID 26378020 DOI: 10.18632/oncotarget.5587  0.36
2015 Roberts RA, Eitas TK, Byrne JD, Johnson BM, Short PJ, McKinnon KP, Reisdorf S, Luft JC, DeSimone JM, Ting JP. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 72: 1-10. PMID 26325217 DOI: 10.1016/j.biomaterials.2015.08.040  0.76
2015 Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE, de Silva AM, Ting JP. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model. Plos One. 10: e0136708. PMID 26301593 DOI: 10.1371/journal.pone.0136708  0.76
2015 Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, et al. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 126: 1621-8. PMID 26265697 DOI: 10.1182/blood-2015-03-634691  0.76
2015 Ting JP, Harton JA. NLRP3 moonlights in TH2 polarization. Nature Immunology. 16: 794-6. PMID 26194278 DOI: 10.1038/ni.3223  0.6
2015 Guo H, Callaway JB, Ting JP. Inflammasomes: mechanism of action, role in disease, and therapeutics. Nature Medicine. 21: 677-87. PMID 26121197 DOI: 10.1038/nm.3893  0.48
2015 Freeman LC, Ting JP. The pathogenic role of the inflammasome in neurodegenerative diseases. Journal of Neurochemistry. PMID 26119245 DOI: 10.1111/jnc.13217  0.76
2015 Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, ... ... Ting JP, et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nature Medicine. PMID 26107252 DOI: 10.1038/nm.3908  0.76
2015 Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. The Journal of Biological Chemistry. 290: 17306-20. PMID 26032420 DOI: 10.1074/jbc.M115.664136  0.76
2015 Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP. Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 589-99. PMID 25596079 DOI: 10.1016/j.nano.2014.11.010  0.76
2015 Fromen CA, Robbins GR, Shen TW, Kai MP, Ting JP, DeSimone JM. Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization. Proceedings of the National Academy of Sciences of the United States of America. 112: 488-93. PMID 25548169 DOI: 10.1073/pnas.1422923112  0.76
2015 Knight ER, Patel EY, Flowers CA, Crowther AJ, Ting JP, Miller CR, Gershon TR, Deshmukh M. ASC deficiency suppresses proliferation and prevents medulloblastoma incidence. Oncogene. 34: 394-402. PMID 24469054 DOI: 10.1038/onc.2013.577  0.76
2015 Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, et al. Suppression of NLRX1 in chronic obstructive pulmonary disease Journal of Clinical Investigation. 125: 2458-2462. DOI: 10.1172/JCI71747  0.76
2014 Giguère PM, Gall BJ, Ezekwe EA, Laroche G, Buckley BK, Kebaier C, Wilson JE, Ting JP, Siderovski DP, Duncan JA. G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3. The Journal of Biological Chemistry. 289: 33245-57. PMID 25271165 DOI: 10.1074/jbc.M114.578393  0.76
2014 Fang L, Gong J, Wang Y, Liu R, Li Z, Wang Z, Zhang Y, Zhang C, Song C, Yang A, Ting JP, Jin B, Chen L. MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 33: 76. PMID 25228093 DOI: 10.1186/s13046-014-0076-7  0.56
2014 Rodgers MA, Bowman JW, Fujita H, Orazio N, Shi M, Liang Q, Amatya R, Kelly TJ, Iwai K, Ting J, Jung JU. The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation. The Journal of Experimental Medicine. 211: 1333-47. PMID 24958845 DOI: 10.1084/jem.20132486  0.76
2014 Guo H, Gao J, Taxman DJ, Ting JP, Su L. HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes. The Journal of Biological Chemistry. 289: 21716-26. PMID 24939850 DOI: 10.1074/jbc.M114.566620  0.6
2014 Robbins GR, Wen H, Ting JP. Inflammasomes and metabolic disorders: old genes in modern diseases. Molecular Cell. 54: 297-308. PMID 24766894 DOI: 10.1016/j.molcel.2014.03.029  0.76
2014 Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 3958-68. PMID 24634494 DOI: 10.4049/jimmunol.1301533  0.76
2014 Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, ... Ting JP, et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41. PMID 24560620 DOI: 10.1016/j.immuni.2014.01.010  0.76
2014 Eitas TK, Chou WC, Wen H, Gris D, Robbins GR, Brickey J, Oyama Y, Ting JP. The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation. The Journal of Biological Chemistry. 289: 4173-9. PMID 24366868 DOI: 10.1074/jbc.M113.533034  0.76
2013 Wen H, Miao EA, Ting JP. Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity. 39: 432-41. PMID 24054327 DOI: 10.1016/j.immuni.2013.08.037  0.52
2013 Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. Embo Reports. 14: 900-6. PMID 24008845 DOI: 10.1038/embor.2013.132  0.76
2013 Jones SW, Roberts RA, Robbins GR, Perry JL, Kai MP, Chen K, Bo T, Napier ME, Ting JP, Desimone JM, Bear JE. Nanoparticle clearance is governed by Th1/Th2 immunity and strain background. The Journal of Clinical Investigation. 123: 3061-73. PMID 23778144 DOI: 10.1172/JCI66895  0.76
2013 Wen H, Ting JP. Agitation by suffocation: how hypoxia activates innate immunity via the Warburg effect. Cell Metabolism. 17: 814-5. PMID 23747241 DOI: 10.1016/j.cmet.2013.05.016  0.52
2013 Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, et al. Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 190: 5722-30. PMID 23630357 DOI: 10.4049/jimmunol.1203343  0.76
2013 Roberts RA, Shen T, Allen IC, Hasan W, DeSimone JM, Ting JP. Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles. Plos One. 8: e62115. PMID 23593509 DOI: 10.1371/journal.pone.0062115  0.76
2013 Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM. Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells. Plos Pathogens. 9: e1003256. PMID 23592984 DOI: 10.1371/journal.ppat.1003256  0.76
2013 Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting JP. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. Plos One. 8: e60842. PMID 23577168 DOI: 10.1371/journal.pone.0060842  0.76
2013 Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X. Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Reports. 3: 678-88. PMID 23434512 DOI: 10.1016/j.celrep.2013.01.029  0.76
2013 Lei Y, Wen H, Ting JP. The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy. 9: 432-3. PMID 23321557 DOI: 10.4161/auto.23026  0.52
2013 Roney K, Holl E, Ting J. Immune plexins and semaphorins: old proteins, new immune functions. Protein & Cell. 4: 17-26. PMID 23307780 DOI: 10.1007/s13238-012-2108-4  0.76
2012 Uittenbogaard AM, Chelvarajan RL, Myers-Morales T, Gorman AA, Brickey WJ, Ye Z, Kaplan AM, Cohen DA, Ting JP, Straley SC. Toward a molecular pathogenic pathway for Yersinia pestis YopM. Frontiers in Cellular and Infection Microbiology. 2: 155. PMID 23248776 DOI: 10.3389/fcimb.2012.00155  0.76
2012 Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH. Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. Plos One. 7: e51105. PMID 23226472 DOI: 10.1371/journal.pone.0051105  0.76
2012 Mendoza AE, Neely CJ, Charles AG, Kartchner LB, Brickey WJ, Khoury AL, Sempowski GD, Ting JP, Cairns BA, Maile R. Radiation combined with thermal injury induces immature myeloid cells. Shock (Augusta, Ga.). 38: 532-42. PMID 23042190 DOI: 10.1097/SHK.0b013e31826c5b19  0.76
2012 Fry RC, Rager JE, Zhou H, Zou B, Brickey JW, Ting J, Lay JC, Peden DB, Alexis NE. Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways. Respiratory Research. 13: 89. PMID 23033980 DOI: 10.1186/1465-9921-13-89  0.76
2012 Holl EK, Roney KE, Allen IC, Steinbach E, Arthur JC, Buntzman A, Plevy S, Frelinger J, Ting JP. Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333. PMID 22916243 DOI: 10.1371/journal.pone.0043333  0.76
2012 Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nature Immunology. 13: 823-31. PMID 22863753 DOI: 10.1038/ni.2378  0.76
2012 Taxman DJ, Swanson KV, Broglie PM, Wen H, Holley-Guthrie E, Huang MT, Callaway JB, Eitas TK, Duncan JA, Ting JP. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. The Journal of Biological Chemistry. 287: 32791-9. PMID 22843689 DOI: 10.1074/jbc.M112.401737  0.76
2012 Taxman DJ, Lei Y, Zhang S, Holley-Guthrie E, Offenbacher S, Ting JP. ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis. Journal of Dental Research. 91: 877-82. PMID 22828789 DOI: 10.1177/0022034512454541  0.6
2012 Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 488: 670-4. PMID 22801494 DOI: 10.1038/nature11290  0.76
2012 Kobayashi T, Matsuoka K, Sheikh SZ, Russo SM, Mishima Y, Collins C, deZoeten EF, Karp CL, Ting JP, Sartor RB, Plevy SE. IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 189: 1792-9. PMID 22786766 DOI: 10.4049/jimmunol.1200042  0.76
2012 Hernandez ML, Herbst M, Lay JC, Alexis NE, Brickey WJ, Ting JP, Zhou H, Peden DB. Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers. The Journal of Allergy and Clinical Immunology. 130: 869-76.e2. PMID 22770265 DOI: 10.1016/j.jaci.2012.05.026  0.56
2012 Kovarova M, Hesker PR, Jania L, Nguyen M, Snouwaert JN, Xiang Z, Lommatzsch SE, Huang MT, Ting JP, Koller BH. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 2006-16. PMID 22753929 DOI: 10.4049/jimmunol.1201065  0.76
2012 Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, ... ... Ting JP, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 36: 933-46. PMID 22749352 DOI: 10.1016/j.immuni.2012.03.025  0.76
2012 Robbins GR, Truax AD, Davis BK, Zhang L, Brickey WJ, Ting JP. Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins. The Journal of Biological Chemistry. 287: 24294-303. PMID 22645137 DOI: 10.1074/jbc.M112.364604  0.76
2012 Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity. 36: 742-54. PMID 22503542 DOI: 10.1016/j.immuni.2012.03.012  0.76
2012 Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, Ting JP, Virgin HW, Kastan MB, Semenkovich CF. Autophagy links inflammasomes to atherosclerotic progression. Cell Metabolism. 15: 534-44. PMID 22440612 DOI: 10.1016/j.cmet.2012.02.011  0.76
2012 Wen H, Ting JP, O'Neill LA. A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation? Nature Immunology. 13: 352-7. PMID 22430788 DOI: 10.1038/ni.2228  0.52
2012 Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Analysis of NLRP3 in the development of allergic airway disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 2884-93. PMID 22323538 DOI: 10.4049/jimmunol.1102488  0.76
2012 Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. Plos One. 7: e29695. PMID 22295065 DOI: 10.1371/journal.pone.0029695  0.76
2012 Allen IC, Lich JD, Arthur JC, Jania CM, Roberts RA, Callaway JB, Tilley SL, Ting JP. Characterization of NLRP12 during the development of allergic airway disease in mice. Plos One. 7: e30612. PMID 22291998 DOI: 10.1371/journal.pone.0030612  0.76
2012 Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP. MyD88 provides a protective role in long-term radiation-induced lung injury. International Journal of Radiation Biology. 88: 335-47. PMID 22248128 DOI: 10.3109/09553002.2012.652723  1
2012 Hernandez M, Brickey WJ, Alexis NE, Fry RC, Rager JE, Zhou B, Ting JP, Zhou H, Peden DB. Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile. The Journal of Allergy and Clinical Immunology. 129: 259-61.e1-2. PMID 22196529 DOI: 10.1016/j.jaci.2011.11.007  0.76
2011 Roney KE, O'Connor BP, Wen H, Holl EK, Guthrie EH, Davis BK, Jones SW, Jha S, Sharek L, Garcia-Mata R, Bear JE, Ting JP. Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. Plos One. 6: e24795. PMID 21966369 DOI: 10.1371/journal.pone.0024795  0.76
2011 Brickey WJ, Alexis NE, Hernandez ML, Reed W, Ting JP, Peden DB. Sputum inflammatory cells from patients with allergic rhinitis and asthma have decreased inflammasome gene expression. The Journal of Allergy and Clinical Immunology. 128: 900-3. PMID 21868073 DOI: 10.1016/j.jaci.2011.08.012  0.56
2011 Barker BR, Taxman DJ, Ting JP. Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. Current Opinion in Immunology. 23: 591-7. PMID 21839623 DOI: 10.1016/j.coi.2011.07.005  0.76
2011 Jorgensen I, Bednar MM, Amin V, Davis BK, Ting JP, McCafferty DG, Valdivia RH. The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host & Microbe. 10: 21-32. PMID 21767809 DOI: 10.1016/j.chom.2011.06.008  0.76
2011 Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/j.immuni.2011.03.026  0.76
2011 Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N. Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood. 118: 2366-74. PMID 21700772 DOI: 10.1182/blood-2011-01-330878  0.76
2011 Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, Lei Y, Gris D, Ting JP. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. The Journal of Biological Chemistry. 286: 19605-16. PMID 21487011 DOI: 10.1074/jbc.M111.221077  0.76
2011 Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature Immunology. 12: 408-15. PMID 21478880 DOI: 10.1038/ni.2022  1
2011 Holl EK, O'Connor BP, Holl TM, Roney KE, Zimmermann AG, Jha S, Kelsoe G, Ting JP. Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. Journal of Immunology (Baltimore, Md. : 1950). 186: 5603-11. PMID 21464091 DOI: 10.4049/jimmunol.1003464  0.76
2011 Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B. Discovery of a viral NLR homolog that inhibits the inflammasome. Science (New York, N.Y.). 331: 330-4. PMID 21252346 DOI: 10.1126/science.1199478  0.76
2011 Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annual Review of Immunology. 29: 707-35. PMID 21219188 DOI: 10.1146/annurev-immunol-031210-101405  0.76
2011 Smith MA, Wright G, Wu J, Tailor P, Ozato K, Chen X, Wei S, Piskurich JF, Ting JP, Wright KL. Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation. The Journal of Biological Chemistry. 286: 7893-904. PMID 21216962 DOI: 10.1074/jbc.M110.165431  0.76
2011 Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Cutting edge: NLRC5-dependent activation of the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 186: 1333-7. PMID 21191067 DOI: 10.4049/jimmunol.1003111  0.76
2011 McNally RS, Davis BK, Clements CM, Accavitti-Loper MA, Mak TW, Ting JP. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB. The Journal of Biological Chemistry. 286: 4098-106. PMID 21097510 DOI: 10.1074/jbc.M110.147371  0.76
2010 van Deventer HW, Burgents JE, Wu QP, Woodford RM, Brickey WJ, Allen IC, McElvania-Tekippe E, Serody JS, Ting JP. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Research. 70: 10161-9. PMID 21159638 DOI: 10.1158/0008-5472.CAN-10-1921  0.76
2010 Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP. The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15811-20. PMID 21106820 DOI: 10.1523/JNEUROSCI.4088-10.2010  0.76
2010 Wen H, Lei Y, Eun SY, Ting JP. Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm. The Journal of Experimental Medicine. 207: 2943-57. PMID 21098092 DOI: 10.1084/jem.20101138  0.76
2010 Huang MT, Mortensen BL, Taxman DJ, Craven RR, Taft-Benz S, Kijek TM, Fuller JR, Davis BK, Allen IC, Brickey WJ, Gris D, Wen H, Kawula TH, Ting JP. Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5476-85. PMID 20921527 DOI: 10.4049/jimmunol.1002154  0.76
2010 Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, ... Ting JP, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4515-9. PMID 20861349 DOI: 10.4049/jimmunol.1002227  0.76
2010 McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, Braunstein M, Ting JP. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. Plos One. 5: e12320. PMID 20808838 DOI: 10.1371/journal.pone.0012320  0.76
2010 Taxman DJ, Huang MT, Ting JP. Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host & Microbe. 8: 7-11. PMID 20638636 DOI: 10.1016/j.chom.2010.06.005  0.6
2010 Gris D, Ye Z, Iocca HA, Wen H, Craven RR, Gris P, Huang M, Schneider M, Miller SD, Ting JP. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 974-81. PMID 20574004 DOI: 10.4049/jimmunol.0904145  0.76
2010 Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. The Journal of Experimental Medicine. 207: 1045-56. PMID 20385749 DOI: 10.1084/jem.20100050  0.76
2010 Taylor LC, Puranam K, Gilmore W, Ting JP, Matsushima GK. 17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss. Neurobiology of Disease. 39: 127-37. PMID 20347981 DOI: 10.1016/j.nbd.2010.03.016  0.76
2010 Davis BK, Ting JP. NLRP3 has a sweet tooth. Nature Immunology. 11: 105-6. PMID 20084064 DOI: 10.1038/ni0210-105  0.76
2010 Ting JP, Duncan JA, Lei Y. How the noninflammasome NLRs function in the innate immune system. Science (New York, N.Y.). 327: 286-90. PMID 20075243 DOI: 10.1126/science.1184004  0.76
2010 Taylor LC, Gilmore W, Ting JP, Matsushima GK. Cuprizone induces similar demyelination in male and female C57BL/6 mice and results in disruption of the estrous cycle. Journal of Neuroscience Research. 88: 391-402. PMID 19746424 DOI: 10.1002/jnr.22215  0.76
2009 Jha S, Ting JP. Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. Journal of Immunology (Baltimore, Md. : 1950). 183: 7623-9. PMID 20007570 DOI: 10.4049/jimmunol.0902425  1
2009 Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. Plos One. 4: e7446. PMID 19826485 DOI: 10.1371/journal.pone.0007446  0.76
2009 Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 2008-15. PMID 19587006 DOI: 10.4049/jimmunol.0900138  0.76
2009 Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 182: 6460-9. PMID 19414800 DOI: 10.4049/jimmunol.0802696  0.76
2009 Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated apoptosis and its inhibition by viral proteins. Plos One. 4: e5466. PMID 19404494 DOI: 10.1371/journal.pone.0005466  0.76
2009 Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/j.immuni.2009.02.005  0.76
2009 Lord CA, Savitsky D, Sitcheran R, Calame K, Wright JR, Ting JP, Williams KL. Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1. Journal of Immunology (Baltimore, Md. : 1950). 182: 2948-58. PMID 19234190 DOI: 10.4049/jimmunol.0801692  0.76
2009 Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, Ting JP. Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 2395-404. PMID 19201894 DOI: 10.4049/jimmunol.0800909  0.76
2008 Hiremath MM, Chen VS, Suzuki K, Ting JP, Matsushima GK. MHC class II exacerbates demyelination in vivo independently of T cells. Journal of Neuroimmunology. 203: 23-32. PMID 18805594 DOI: 10.1016/j.jneuroim.2008.06.034  0.76
2008 Attia RR, Gardner LA, Mahrous E, Taxman DJ, Legros L, Rowe S, Ting JP, Geller A, Kotb M. Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. The Journal of Biological Chemistry. 283: 30788-95. PMID 18753136 DOI: 10.1074/jbc.M804159200  0.6
2008 O'Connor BP, Eun SY, Ye Z, Zozulya AL, Lich JD, Moore CB, Iocca HA, Roney KE, Holl EK, Wu QP, van Deventer HW, Fabry Z, Ting JP. Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 13015-20. PMID 18728195 DOI: 10.1073/pnas.0803386105  0.76
2008 O'Connor BP, Ting JP. The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function. Immunologic Research. 41: 217-22. PMID 18649144 DOI: 10.1007/s12026-008-8026-0  0.44
2008 Willingham SB, Ting JP. NLRs and the dangers of pollution and aging. Nature Immunology. 9: 831-3. PMID 18645588 DOI: 10.1038/ni0808-831  0.76
2008 Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. Journal of Immunology (Baltimore, Md. : 1950). 181: 17-21. PMID 18566365  0.76
2008 Moore CB, Ting JP. Regulation of mitochondrial antiviral signaling pathways. Immunity. 28: 735-9. PMID 18549796 DOI: 10.1016/j.immuni.2008.05.005  0.56
2008 van Deventer HW, Wu QP, Bergstralh DT, Davis BK, O'Connor BP, Ting JP, Serody JS. C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9. The American Journal of Pathology. 173: 253-64. PMID 18535183 DOI: 10.2353/ajpath.2008.070732  0.76
2008 Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes & Development. 22: 1490-500. PMID 18519641 DOI: 10.1101/gad.1662308  0.76
2008 Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, Peden DB. Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 100: 206-15. PMID 18426139 DOI: 10.1016/S1081-1206(10)60444-9  0.56
2008 Ting JP, Willingham SB, Bergstralh DT. NLRs at the intersection of cell death and immunity. Nature Reviews. Immunology. 8: 372-9. PMID 18362948 DOI: 10.1038/nri2296  0.76
2008 Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, et al. The NLR gene family: a standard nomenclature. Immunity. 28: 285-7. PMID 18341998 DOI: 10.1016/j.immuni.2008.02.005  0.76
2008 Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Current Opinion in Immunology. 20: 3-9. PMID 18280719 DOI: 10.1016/j.coi.2008.01.003  0.76
2008 Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. Molecular Immunology. 45: 2214-24. PMID 18215421 DOI: 10.1016/j.molimm.2007.12.001  0.76
2008 Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, Ting JP. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. Journal of Neuroimmunology. 194: 97-106. PMID 18207576 DOI: 10.1016/j.jneuroim.2007.12.003  0.76
2008 Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature. 451: 573-7. PMID 18200010 DOI: 10.1038/nature06501  0.76
2008 Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, Ting JP. ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. Molecular and Cellular Biology. 28: 1841-50. PMID 18160710 DOI: 10.1128/MCB.01468-07  0.76
2008 McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, Marriott I. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 30-40. PMID 17907925 DOI: 10.1359/jbmr.071002  0.76
2007 Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host & Microbe. 2: 147-59. PMID 18005730 DOI: 10.1016/j.chom.2007.07.009  0.76
2007 Arthur JC, Lich JD, Aziz RK, Kotb M, Ting JP. Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. Journal of Immunology (Baltimore, Md. : 1950). 179: 6291-6. PMID 17947705  0.76
2007 Moore CB, Medina MA, van Deventer HW, O'Connor BP, Cameron S, Taxman DJ, Maile R, Ting JP, Cairns BA. Downregulation of immune signaling genes in patients with large surface burn injury. Journal of Burn Care & Research : Official Publication of the American Burn Association. 28: 879-87. PMID 17925653 DOI: 10.1097/BCR.0b013e318159a41e  0.6
2007 Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, Ting JP. Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7429-37. PMID 17626203 DOI: 10.1523/JNEUROSCI.1307-07.2007  0.76
2007 Lich JD, Ting JP. CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses. Proceedings of the American Thoracic Society. 4: 263-6. PMID 17607010 DOI: 10.1513/pats.200701-022AW  0.6
2007 Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 8041-6. PMID 17483456 DOI: 10.1073/pnas.0611496104  0.76
2007 Lich JD, Ting JP. Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions. Microbes and Infection / Institut Pasteur. 9: 672-6. PMID 17418609 DOI: 10.1016/j.micinf.2007.01.018  0.6
2007 Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, Ting JP. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 178: 1256-60. PMID 17237370 DOI: 10.4049/jimmunol.178.3.1256  0.76
2007 Shabman RS, Morrison TE, Moore C, White L, Suthar MS, Hueston L, Rulli N, Lidbury B, Ting JP, Mahalingam S, Heise MT. Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses. Journal of Virology. 81: 237-47. PMID 17079324 DOI: 10.1128/JVI.01590-06  0.36
2007 Bergstralh DT, Conti BJ, Moore CB, Brickey WJ, Taxman DJ, Ting JP. Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Experimental Cell Research. 313: 65-76. PMID 17069796 DOI: 10.1016/j.yexcr.2006.09.016  0.76
2006 Kurtz S, McKinnon KP, Runge MS, Ting JP, Braunstein M. The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response. Infection and Immunity. 74: 6855-64. PMID 17030572 DOI: 10.1128/IAI.01022-06  0.52
2006 Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proceedings of the National Academy of Sciences of the United States of America. 103: 15091-6. PMID 17015834 DOI: 10.1073/pnas.0607260103  0.76
2006 Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, Ting JP. Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 4271-5. PMID 16982860  0.76
2006 Taxman DJ, Zhang J, Champagne C, Bergstralh DT, Iocca HA, Lich JD, Ting JP. Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 177: 4252-6. PMID 16982856  0.76
2006 Wright KL, Ting JP. Epigenetic regulation of MHC-II and CIITA genes. Trends in Immunology. 27: 405-12. PMID 16870508 DOI: 10.1016/  0.76
2006 Lich JD, Arthur JC, Ting JP. Cryopyrin: in from the cold. Immunity. 24: 241-3. PMID 16546091 DOI: 10.1016/j.immuni.2006.03.004  0.76
2006 Bergstralh DT, Ting JP. Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treatment Reviews. 32: 166-79. PMID 16527420 DOI: 10.1016/j.ctrv.2006.01.004  0.76
2006 Taxman DJ, Livingstone LR, Zhang J, Conti BJ, Iocca HA, Williams KL, Lich JD, Ting JP, Reed W. Criteria for effective design, construction, and gene knockdown by shRNA vectors. Bmc Biotechnology. 6: 7. PMID 16433925 DOI: 10.1186/1472-6750-6-7  0.76
2006 McIntosh K, Zvonic S, Garrett S, Mitchell JB, Floyd ZE, Hammill L, Kloster A, Di Halvorsen Y, Ting JP, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM. The immunogenicity of human adipose-derived cells: temporal changes in vitro. Stem Cells (Dayton, Ohio). 24: 1246-53. PMID 16410391 DOI: 10.1634/stemcells.2005-0235  0.76
2006 Plant SR, Wang Y, Vasseur S, Thrash JC, McMahon EJ, Bergstralh DT, Arnett HA, Miller SD, Carson MJ, Iovanna JL, Ting JP. Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia. 53: 529-37. PMID 16374777 DOI: 10.1002/glia.20297  0.76
2006 Hoffman BG, Williams KL, Tien AH, Lu V, de Algara TR, Ting JP, Helgason CD. Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function. Genes and Immunity. 7: 101-12. PMID 16355110 DOI: 10.1038/sj.gene.6364270  0.76
2006 Chalermskulrat W, McKinnon KP, Brickey WJ, Neuringer IP, Park RC, Sterka DG, Long BR, McNeillie P, Noelle RJ, Ting JP, Aris RM. Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance. Thorax. 61: 61-7. PMID 16254057 DOI: 10.1136/thx.2005.047316  0.76
2005 Zika E, Fauquier L, Vandel L, Ting JP. Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 16321-6. PMID 16254053 DOI: 10.1073/pnas.0505045102  0.76
2005 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/jbc.M502820200  0.76
2005 Reiman R, Campos Torres A, Martin BK, Ting JP, Campbell IL, Barnum SR. Expression of C5a in the brain does not exacerbate experimental autoimmune encephalomyelitis. Neuroscience Letters. 390: 134-8. PMID 16154690 DOI: 10.1016/j.neulet.2005.08.022  0.76
2005 Wang AH, Grégoire S, Zika E, Xiao L, Li CS, Li H, Wright KL, Ting JP, Yang XJ. Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases. The Journal of Biological Chemistry. 280: 29117-27. PMID 15964851 DOI: 10.1074/jbc.M500295200  0.76
2005 Johnnidis JB, Venanzi ES, Taxman DJ, Ting JP, Benoist CO, Mathis DJ. Chromosomal clustering of genes controlled by the aire transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 102: 7233-8. PMID 15883360 DOI: 10.1073/pnas.0502670102  0.6
2005 Ting JP, Williams KL. The CATERPILLER family: an ancient family of immune/apoptotic proteins. Clinical Immunology (Orlando, Fla.). 115: 33-7. PMID 15870018 DOI: 10.1016/j.clim.2005.02.007  0.76
2005 van Deventer HW, O'Connor W, Brickey WJ, Aris RM, Ting JP, Serody JS. C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis. Cancer Research. 65: 3374-9. PMID 15833871 DOI: 10.1158/0008-5472.CAN-04-2616  0.76
2005 Ting JP, Davis BK. CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annual Review of Immunology. 23: 387-414. PMID 15771576 DOI: 10.1146/annurev.immunol.23.021704.115616  0.76
2005 Conti BJ, Davis BK, Zhang J, O'connor W, Williams KL, Ting JP. CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. The Journal of Biological Chemistry. 280: 18375-85. PMID 15705585 DOI: 10.1074/jbc.M413169200  0.76
2005 Zika E, Ting JP. Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Current Opinion in Immunology. 17: 58-64. PMID 15653312 DOI: 10.1016/j.coi.2004.11.008  0.76
2005 Plant SR, Arnett HA, Ting JP. Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination. Glia. 49: 1-14. PMID 15382206 DOI: 10.1002/glia.20089  0.76
2004 Bergstralh DT, Taxman DJ, Chou TC, Danishefsky SJ, Ting JP. A comparison of signaling activities induced by Taxol and desoxyepothilone B. Journal of Chemotherapy (Florence, Italy). 16: 563-76. PMID 15700849 DOI: 10.1179/joc.2004.16.6.563  0.76
2004 Greer SF, Harton JA, Linhoff MW, Janczak CA, Ting JP, Cressman DE. Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 173: 376-83. PMID 15210796  0.76
2004 Arancibia-Cárcamo CV, Osawa H, Arnett HA, Háskova Z, George AJ, Ono SJ, Ting JP, Streilein JW. A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. European Journal of Immunology. 34: 471-80. PMID 14768052 DOI: 10.1002/eji.200324195  0.76
2003 O'Connor W, Harton JA, Zhu X, Linhoff MW, Ting JP. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. Journal of Immunology (Baltimore, Md. : 1950). 171: 6329-33. PMID 14662828  0.76
2003 Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9824-32. PMID 14586011  0.76
2003 MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. Cancer Research. 63: 6928-34. PMID 14583493  0.76
2003 Greer SF, Zika E, Conti B, Zhu XS, Ting JP. Enhancement of CIITA transcriptional function by ubiquitin. Nature Immunology. 4: 1074-82. PMID 14528304 DOI: 10.1038/ni985  0.76
2003 Taxman DJ, MacKeigan JP, Clements C, Bergstralh DT, Ting JP. Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. Cancer Research. 63: 5095-104. PMID 12941840  0.76
2003 Wong AW, Brickey WJ, Taxman DJ, van Deventer HW, Reed W, Gao JX, Zheng P, Liu Y, Li P, Blum JS, McKinnon KP, Ting JP. CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nature Immunology. 4: 891-8. PMID 12910265 DOI: 10.1038/ni960  0.76
2003 Repique CJ, Li A, Brickey WJ, Ting JP, Collins FM, Morris SL. Susceptibility of mice deficient in the MHC class II transactivator to infection with Mycobacterium tuberculosis. Scandinavian Journal of Immunology. 58: 15-22. PMID 12828554  0.56
2003 Williams KL, Taxman DJ, Linhoff MW, Reed W, Ting JP. Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. Journal of Immunology (Baltimore, Md. : 1950). 170: 5354-8. PMID 12759408  0.76
2003 Zika E, Greer SF, Zhu XS, Ting JP. Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. Molecular and Cellular Biology. 23: 3091-102. PMID 12697811 DOI: 10.1128/MCB.23.9.3091-3102.2003  0.76
2003 Chalermskulrat W, Neuringer IP, Brickey WJ, Felix NJ, Randell SH, Ting JP, Aris RM. Hierarchical contributions of allorecognition pathways in chronic lung rejection. American Journal of Respiratory and Critical Care Medicine. 167: 999-1007. PMID 12446274 DOI: 10.1164/rccm.200209-1099OC  0.76
2002 June Brickey W, Felix NJ, Griffiths R, Zhang J, Wang B, Piskurich JF, Itoh-Lindstrom Y, Coffman TM, Ting JP. Prolonged survival of class II transactivator-deficient cardiac allografts. Transplantation. 74: 1341-8. PMID 12451276 DOI: 10.1097/01.TP.0000036052.32503.5A  0.6
2002 Harton JA, Linhoff MW, Zhang J, Ting JP. Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. Journal of Immunology (Baltimore, Md. : 1950). 169: 4088-93. PMID 12370334  0.76
2002 Wong AW, Ghosh N, McKinnon KP, Reed W, Piskurich JF, Wright KL, Ting JP. Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line. Journal of Immunology (Baltimore, Md. : 1950). 169: 3112-9. PMID 12218128  0.76
2002 van Deventer HW, Serody JS, McKinnon KP, Clements C, Brickey WJ, Ting JP. Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. Journal of Immunology (Baltimore, Md. : 1950). 169: 1634-9. PMID 12133994  0.76
2002 MacKeigan JP, Taxman DJ, Hunter D, Earp HS, Graves LM, Ting JP. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2091-9. PMID 12114408  0.76
2002 Harton JA, O'Connor W, Conti BJ, Linhoff MW, Ting JP. Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Human Immunology. 63: 588-601. PMID 12072194 DOI: 10.1016/S0198-8859(02)00400-7  0.76
2002 Tompkins SM, Padilla J, Dal Canto MC, Ting JP, Van Kaer L, Miller SD. De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 4173-83. PMID 11937578  0.32
2002 Felix NJ, de Serres S, Meyer AA, Ting JP. Comparison of Abeta(b-/-), H2-DM(-), and CIITA(-/-) in second-set skin allograft rejection. The Journal of Surgical Research. 102: 185-92. PMID 11796017 DOI: 10.1006/jsre.2001.6311  0.76
2002 Arnett HA, Hellendall RP, Matsushima GK, Suzuki K, Laubach VE, Sherman P, Ting JP. The protective role of nitric oxide in a neurotoxicant-induced demyelinating model. Journal of Immunology (Baltimore, Md. : 1950). 168: 427-33. PMID 11751989  0.76
2001 Morrison TE, Mauser A, Wong A, Ting JP, Kenney SC. Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early protein. Immunity. 15: 787-99. PMID 11728340 DOI: 10.1016/S1074-7613(01)00226-6  0.76
2001 Arnett HA, Mason J, Marino M, Suzuki K, Matsushima GK, Ting JP. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nature Neuroscience. 4: 1116-22. PMID 11600888 DOI: 10.1038/nn738  0.76
2001 Zhu XS, Ting JP. A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters. Molecular and Cellular Biology. 21: 7078-88. PMID 11564890 DOI: 10.1128/MCB.21.20.7078-7088.2001  0.76
2001 Cressman DE, O'Connor WJ, Greer SF, Zhu XS, Ting JP. Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator. Journal of Immunology (Baltimore, Md. : 1950). 167: 3626-34. PMID 11564775 DOI: 10.4049/jimmunol.167.7.3626  0.76
2001 Harton JA, Zika E, Ting JP. The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator. The Journal of Biological Chemistry. 276: 38715-20. PMID 11514574 DOI: 10.1074/jbc.M106652200  0.76
2001 Deffrennes V, Vedrenne J, Stolzenberg MC, Piskurich J, Barbieri G, Ting JP, Charron D, Alcaïde-Loridan C. Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B cell-specific promoter. Journal of Immunology (Baltimore, Md. : 1950). 167: 98-106. PMID 11418637  0.76
2001 Li G, Harton JA, Zhu X, Ting JP. Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Molecular and Cellular Biology. 21: 4626-35. PMID 11416140 DOI: 10.1128/MCB.21.14.4626-4635.2001  0.6
2001 Linhoff MW, Harton JA, Cressman DE, Martin BK, Ting JP. Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains. Molecular and Cellular Biology. 21: 3001-11. PMID 11287606 DOI: 10.1128/MCB.21.9.3001-3011.2001  0.76
2001 Taxman DJ, Ting JP. Identification of novel Mycoplasma hyorhinis gene fragments by differential display analysis of co-cultures. Journal of Microbiological Methods. 44: 217-23. PMID 11240044  0.6
2000 Piskurich JF, Lin KI, Lin Y, Wang Y, Ting JP, Calame K. BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nature Immunology. 1: 526-32. PMID 11101876 DOI: 10.1038/82788  0.76
2000 MacKeigan JP, Collins TS, Ting JP. MEK inhibition enhances paclitaxel-induced tumor apoptosis. The Journal of Biological Chemistry. 275: 38953-6. PMID 11038347 DOI: 10.1074/jbc.C000684200  0.76
2000 Harton JA, Ting JP. Class II transactivator: mastering the art of major histocompatibility complex expression. Molecular and Cellular Biology. 20: 6185-94. PMID 10938095 DOI: 10.1128/MCB.20.17.6185-6194.2000  0.6
2000 Chatterjee-Kishore M, Wright KL, Ting JP, Stark GR. How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. The Embo Journal. 19: 4111-22. PMID 10921891 DOI: 10.1093/emboj/19.15.4111  0.76
2000 Zhu XS, Linhoff MW, Li G, Chin KC, Maity SN, Ting JP. Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter. Molecular and Cellular Biology. 20: 6051-61. PMID 10913187 DOI: 10.1128/MCB.20.16.6051-6061.2000  0.76
2000 Taxman DJ, Cressman DE, Ting JP. Identification of class II transcriptional activator-induced genes by representational difference analysis: discoordinate regulation of the DN alpha/DO beta heterodimer. Journal of Immunology (Baltimore, Md. : 1950). 165: 1410-6. PMID 10903745  0.6
2000 Felix NJ, Brickey WJ, Griffiths R, Zhang J, Van Kaer L, Coffman T, Ting JP. H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection. The Journal of Experimental Medicine. 192: 31-40. PMID 10880524 DOI: 10.1084/jem.192.1.31  0.76
2000 Collins TS, Lee LF, Ting JP. Paclitaxel up-regulates interleukin-8 synthesis in human lung carcinoma through an NF-kappaB- and AP-1-dependent mechanism. Cancer Immunology, Immunotherapy : Cii. 49: 78-84. PMID 10823417 DOI: 10.1007/s002620050605  0.76
2000 Saifuddin M, Roebuck KA, Chang Ch, Ting JP, Spear GT. Cutting edge: activation of HIV-1 transcription by the MHC class II transactivator. Journal of Immunology (Baltimore, Md. : 1950). 164: 3941-5. PMID 10754282  0.76
2000 Lee LF, Hellendall RP, Wang Y, Haskill JS, Mukaida N, Matsushima K, Ting JP. IL-8 reduced tumorigenicity of human ovarian cancer in vivo due to neutrophil infiltration. Journal of Immunology (Baltimore, Md. : 1950). 164: 2769-75. PMID 10679119  0.56
1999 Ting JP, Zhu XS. Class II MHC genes: a model gene regulatory system with great biologic consequences. Microbes and Infection / Institut Pasteur. 1: 855-61. PMID 10614002  0.76
1999 Brickey WJ, Wright KL, Zhu XS, Ting JP. Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor. Journal of Immunology (Baltimore, Md. : 1950). 163: 6622-30. PMID 10586057  0.76
1999 Ghosh N, Piskurich JF, Wright G, Hassani K, Ting JP, Wright KL. A novel element and a TEF-2-like element activate the major histocompatibility complex class II transactivator in B-lymphocytes. The Journal of Biological Chemistry. 274: 32342-50. PMID 10542275 DOI: 10.1074/jbc.274.45.32342  0.76
1999 Nikcevich KM, Piskurich JF, Hellendall RP, Wang Y, Ting JP. Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha. Journal of Neuroimmunology. 99: 195-204. PMID 10505975  0.56
1999 Harton JA, Cressman DE, Chin KC, Der CJ, Ting JP. GTP binding by class II transactivator: role in nuclear import. Science (New York, N.Y.). 285: 1402-5. PMID 10464099 DOI: 10.1126/science.285.5432.1402  0.6
1999 Itoh-Lindstrom Y, Piskurich JF, Felix NJ, Wang Y, Brickey WJ, Platt JL, Koller BH, Ting JP. Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain. Journal of Immunology (Baltimore, Md. : 1950). 163: 2425-31. PMID 10452977  0.56
1999 Martin BK, Frelinger JG, Ting JP. Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth. Journal of Immunology (Baltimore, Md. : 1950). 162: 6663-70. PMID 10352284  0.76
1999 Cressman DE, Chin KC, Taxman DJ, Ting JP. A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome. Immunity. 10: 163-71. PMID 10072069  0.6
1999 Piskurich JF, Linhoff MW, Wang Y, Ting JP. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Molecular and Cellular Biology. 19: 431-40. PMID 9858567  0.76
1998 Hiremath MM, Saito Y, Knapp GW, Ting JP, Suzuki K, Matsushima GK. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. Journal of Neuroimmunology. 92: 38-49. PMID 9916878 DOI: 10.1016/S0165-5728(98)00168-4  0.76
1998 Lee LF, Li G, Templeton DJ, Ting JP. Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK). The Journal of Biological Chemistry. 273: 28253-60. PMID 9774447  0.44
1998 Wright KL, Chin KC, Linhoff M, Skinner C, Brown JA, Boss JM, Stark GR, Ting JP. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 6267-72. PMID 9600954 DOI: 10.1073/pnas.95.11.6267  0.76
1998 White CM, Martin BK, Lee LF, Haskill JS, Ting JP. Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells. Cancer Immunology, Immunotherapy : Cii. 46: 104-12. PMID 9558006 DOI: 10.1007/s002620050468  0.76
1998 Piskurich JF, Wang Y, Linhoff MW, White LC, Ting JP. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. Journal of Immunology (Baltimore, Md. : 1950). 160: 233-40. PMID 9551976  0.76
1997 Ting JP, Wright KL, Chin KC, Brickey WJ, Li G. The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression. Journal of Immunology (Baltimore, Md. : 1950). 159: 5457-62. PMID 9548486  0.76
1997 Chin KC, Li G, Ting JP. Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants. Journal of Immunology (Baltimore, Md. : 1950). 159: 2789-94. PMID 9300700  0.44
1997 Zimmermann AG, Wright KL, Ting JP, Mitchell BS. Regulation of inosine-5'-monophosphate dehydrogenase type II gene expression in human T cells. Role for a novel 5' palindromic octamer sequence. The Journal of Biological Chemistry. 272: 22913-23. PMID 9278455 DOI: 10.1074/jbc.272.36.22913  0.76
1997 Linhoff MW, Wright KL, Ting JP. CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model. Molecular and Cellular Biology. 17: 4589-96. PMID 9234716  0.76
1997 Katula KS, Wright KL, Paul H, Surman DR, Nuckolls FJ, Smith JW, Ting JP, Yates J, Cogswell JP. Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 811-20. PMID 9218875  0.76
1997 Armstrong TD, Clements VK, Martin BK, Ting JP, Ostrand-Rosenberg S. Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proceedings of the National Academy of Sciences of the United States of America. 94: 6886-91. PMID 9192661 DOI: 10.1073/pnas.94.13.6886  0.76
1997 Martin BK, Chin KC, Olsen JC, Skinner CA, Dey A, Ozato K, Ting JP. Induction of MHC class I expression by the MHC class II transactivator CIITA. Immunity. 6: 591-600. PMID 9175837 DOI: 10.1016/S1074-7613(00)80347-7  0.76
1997 Chin KC, Li GG, Ting JP. Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. Proceedings of the National Academy of Sciences of the United States of America. 94: 2501-6. PMID 9122224  0.44
1996 White LC, Wright KL, Felix NJ, Ruffner H, Reis LF, Pine R, Ting JP. Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. Immunity. 5: 365-76. PMID 8885869 DOI: 10.1016/S1074-7613(00)80262-9  0.76
1996 Lee LF, Schuerer-Maly CC, Lofquist AK, van Haaften-Day C, Ting JP, White CM, Martin BK, Haskill JS. Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. Cancer Research. 56: 1303-8. PMID 8640818  0.76
1995 Wright KL, White LC, Kelly A, Beck S, Trowsdale J, Ting JP. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. The Journal of Experimental Medicine. 181: 1459-71. PMID 7699330 DOI: 10.1084/jem.181.4.1459  0.76
1995 Wright KL, Moore TL, Vilen BJ, Brown AM, Ting JP. Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y. The Journal of Biological Chemistry. 270: 20978-86. PMID 7673122 DOI: 10.1074/jbc.270.36.20978  0.76
1994 Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin AS, Basta PV, Ting JP. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits. Molecular and Cellular Biology. 14: 2926-35. PMID 8164652 DOI: 10.1128/MCB.14.5.2926  0.76
1994 Ting JP, Painter A, Zeleznik-Le NJ, MacDonald G, Moore TM, Brown A, Schwartz BD. YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes. The Journal of Experimental Medicine. 179: 1605-11. PMID 8163940  0.76
1994 Wright KL, Vilen BJ, Itoh-Lindstrom Y, Moore TL, Li G, Criscitiello M, Cogswell P, Clarke JB, Ting JP. CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors. The Embo Journal. 13: 4042-53. PMID 8076600  0.76
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  0.76
1994 Chen X, Wright KL, Berkowitz EA, Azizkhan JC, Ting JP, Lee DC. Protein interactions at Sp1-like sites in the TGF alpha promoter as visualized by in vivo genomic footprinting. Oncogene. 9: 3179-87. PMID 7936640  0.76
1993 Cogswell JP, Cogswell PC, Kuehl WM, Cuddihy AM, Bender TM, Engelke U, Marcu KB, Ting JP. Mechanism of c-myc regulation by c-Myb in different cell lineages. Molecular and Cellular Biology. 13: 2858-69. PMID 8474446  0.52
1993 Matsushima GK, Itoh-Lindstrom Y, Ting JP. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Molecular and Cellular Biology. 13: 5132. PMID 8336739  0.76
1993 Brown AM, Wright KL, Ting JP. Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-gamma-induced expression. The Journal of Biological Chemistry. 268: 26328-33. PMID 8253755  0.76
1992 Zeleznik-Le NJ, Itoh-Lindstrom Y, Clarke JB, Moore TL, Ting JP. The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA. The Journal of Biological Chemistry. 267: 7677-82. PMID 1560002  0.76
1992 Wright KL, Ting JP. In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma. Proceedings of the National Academy of Sciences of the United States of America. 89: 7601-5. PMID 1502171  0.76
1992 Matsushima GK, Itoh-Lindstrom Y, Ting JP. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Molecular and Cellular Biology. 12: 5610-9. PMID 1448091  0.76
1992 Vilen BJ, Penta JF, Ting JP. Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene. The Journal of Biological Chemistry. 267: 23728-34. PMID 1331098  0.76
1991 Vilen BJ, Cogswell JP, Ting JP. Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Molecular and Cellular Biology. 11: 2406-15. PMID 1901941  0.76
1991 Zeleznik-Le NJ, Azizkhan JC, Ting JP. Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 88: 1873-7. PMID 1848012  0.76
1990 Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science (New York, N.Y.). 247: 1581-4. PMID 2321018  0.76
1990 Evans JL, Moore TL, Kuehl WM, Bender T, Ting JP. Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter. Molecular and Cellular Biology. 10: 5747-52. PMID 2233716 DOI: 10.1128/MCB.10.11.5747  0.52
1990 Sasaki A, Levison SW, Ting JP. Differential suppression of interferon-gamma-induced Ia antigen expression on cultured rat astroglia and microglia by second messengers. Journal of Neuroimmunology. 29: 213-22. PMID 2170439 DOI: 10.1016/0165-5728(90)90164-I  0.76
1989 Sasaki A, Levison SW, Ting JP. Comparison and quantitation of Ia antigen expression on cultured macroglia and ameboid microglia from Lewis rat cerebral cortex: analyses and implications. Journal of Neuroimmunology. 25: 63-74. PMID 2584392 DOI: 10.1016/0165-5728(89)90087-8  0.76
1989 Sherman PA, Basta PV, Moore TL, Brown AM, Ting JP. Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins. Molecular and Cellular Biology. 9: 50-6. PMID 2538724 DOI: 10.1128/MCB.9.1.50  0.52
1989 Sherman PA, Basta PV, Heguy A, Wloch MK, Roeder RG, Ting JP. The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter. Proceedings of the National Academy of Sciences of the United States of America. 86: 6739-43. PMID 2505259  0.76
1989 Basta PV, Moore TL, Yokota S, Ting JP. A beta-adrenergic agonist modulates DR alpha gene transcription via enhanced cAMP levels in a glioblastoma multiforme line. Journal of Immunology (Baltimore, Md. : 1950). 142: 2895-901. PMID 2467944  0.76
1987 Ting JP, Takiguchi M, Macchi M, Frelinger JA. The expression and detection of MHC class I antigens on murine neuroblastoma and ependymoblastoma lines. Journal of Neuroimmunology. 14: 87-98. PMID 3492512 DOI: 10.1016/0165-5728(87)90103-2  0.76
1987 Evans JL, Boyle WJ, Ting JP. Molecular basis of elevated c-myb expression in the abnormal L3T4-, Lyt-2- T lymphocytes of autoimmune mice. Journal of Immunology (Baltimore, Md. : 1950). 139: 3497-505. PMID 3316384  0.76
1985 Takiguchi M, Ting JP, Buessow SC, Boyer C, Gillespie Y, Frelinger JA. Response of glioma cells to interferon-gamma: increase in class II RNA, protein and mixed lymphocyte reaction-stimulating ability. European Journal of Immunology. 15: 809-14. PMID 2411569 DOI: 10.1002/eji.1830150813  0.76
1983 Ting JP, Nixon DF, Weiner LP, Frelinger JA. Brain Ia antigens have a bone marrow origin. Immunogenetics. 17: 295-301. PMID 6572615 DOI: 10.1007/BF00364413  0.76
1982 Nixon DF, Ting JP, Frelinger JA. Ia antigens on non-lymphoid tissues their origins and functions. Immunology Today. 3: 339-42. PMID 25290677 DOI: 10.1016/0167-5699(82)90019-6  0.76
1981 Ting JP, Shigekawa BL, Linthicum DS, Weiner LP, Frelinger JA. Expression and synthesis of murine immune response-associated (Ia) antigens by brain cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3170-4. PMID 6166944 DOI: 10.1073/pnas.78.5.3170  0.76
1980 Ting JP, Ranney DF. Selective suppression of the murine autologous mixed lymphocyte reaction by physiological concentrations of hydrocortisone: effects on cell-surface Ia antigens. Cellular Immunology. 53: 138-50. PMID 6447544  0.76
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