Jenny P-Y Ting - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroinflammation

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang M, Rousseau B, Qiu K, Huang G, Zhang Y, Su H, Le Bihan-Benjamin C, Khati I, Artz O, Foote MB, Cheng YY, Lee KH, Miao MZ, Sun Y, Bousquet PJ, ... ... Ting JP, et al. Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses. Nature Biotechnology. PMID 37749267 DOI: 10.1038/s41587-023-01957-8  0.568
2023 Chou WC, Jha S, Linhoff MW, Ting JP. Author Correction: The NLR gene family: from discovery to present day. Nature Reviews. Immunology. PMID 37198352 DOI: 10.1038/s41577-023-00891-9  0.738
2023 Chou WC, Jha S, Linhoff MW, Ting JP. The NLR gene family: from discovery to present day. Nature Reviews. Immunology. PMID 36973360 DOI: 10.1038/s41577-023-00849-x  0.795
2022 Barnett KC, Xie Y, Asakura T, Song D, Liang K, Taft-Benz SA, Guo H, Yang S, Okuda K, Gilmore RC, Loome JF, Oguin Iii TH, Sempowski GD, Randell SH, Heise MT, ... ... Ting JP, et al. An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2. Cell Host & Microbe. PMID 36563691 DOI: 10.1016/j.chom.2022.12.005  0.412
2022 Li S, Mirlekar B, Johnson BM, Brickey WJ, Wrobel JA, Yang N, Song D, Entwistle S, Tan X, Deng M, Cui Y, Li W, Vincent BG, Gale M, Pylayeva-Gupta Y, ... Ting JP, et al. STING-induced regulatory B cells compromise NK function in cancer immunity. Nature. PMID 36198789 DOI: 10.1038/s41586-022-05254-3  0.626
2022 Mirlekar B, Wang Y, Li S, Zhou M, Entwistle S, De Buysscher T, Morrison A, Herrera G, Harris C, Vincent BG, Ting JP, Rashid N, Kim WY, Yeh JJ, Pylayeva-Gupta Y. Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity. Cell Reports. Medicine. 3: 100744. PMID 36099917 DOI: 10.1016/j.xcrm.2022.100744  0.604
2020 Deng M, Tam JW, Wang L, Liang K, Li S, Zhang L, Guo H, Luo X, Zhang Y, Petrucelli A, Davis BK, Conti BJ, June Brickey W, Ko CC, Lei YL, ... ... Ting JP, et al. TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. Nature Communications. 11: 2193. PMID 32366851 DOI: 10.1038/S41467-020-16014-0  0.783
2019 Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, ... ... Ting JP, et al. Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD. Blood. PMID 31533918 DOI: 10.1182/Blood.2019001950  0.529
2019 Gharagozloo M, Mahmoud S, Simard C, Yamamoto K, Bobbala D, Ilangumaran S, Smith MD, Lamontagne A, Jarjoura S, Denault JB, Blais V, Gendron L, Vilariño-Güell C, Sadovnick AD, Ting JP, et al. NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity. Plos Biology. 17: e3000451. PMID 31525189 DOI: 10.1371/Journal.Pbio.3000451  0.381
2019 Chen ST, Chen L, Lin DS, Chen SY, Tsao YP, Guo H, Li FJ, Tseng WT, Tam JW, Chao CW, Brickey WJ, Dzhagalov I, Song MJ, Kang HR, Jung JU, ... Ting JP, et al. NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25. Cell Host & Microbe. PMID 30902577 DOI: 10.1016/J.Chom.2019.02.013  0.302
2019 Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP. Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. Immunity. 50: 591-599.e6. PMID 30893587 DOI: 10.1016/J.Immuni.2019.02.009  0.327
2018 Huang JH, Liu CY, Wu SY, Chen WY, Chang TH, Kan HW, Hsieh ST, Ting JP, Wu-Hsieh BA. NLRX1 Facilitates -Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages. Frontiers in Immunology. 9: 2761. PMID 30559741 DOI: 10.3389/fimmu.2018.02761  0.306
2018 Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Acetalated Dextran microparticles for co-delivery of STING and TLR7/8 agonists. Molecular Pharmaceutics. PMID 30281314 DOI: 10.1021/Acs.Molpharmaceut.8B00579  0.332
2018 Shao W, Earley LF, Chai Z, Chen X, Sun J, He T, Deng M, Hirsch ML, Ting J, Samulski RJ, Li C. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction. Jci Insight. 3. PMID 29925692 DOI: 10.1172/jci.insight.120474  0.356
2017 Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29170142 DOI: 10.1016/J.Jconrel.2017.11.030  0.334
2017 Rotty JD, Brighton HE, Craig SL, Asokan SB, Cheng N, Ting JP, Bear JE. Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility. Developmental Cell. PMID 28867487 DOI: 10.1016/J.Devcel.2017.08.003  0.325
2017 Freeman L, Guo H, David CN, Brickey WJ, Jha S, Ting JP. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. The Journal of Experimental Medicine. PMID 28404595 DOI: 10.1084/Jem.20150237  0.583
2017 Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JP, Woosley JT, Blazar BR, Zaiss DM, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. The Journal of Clinical Investigation. PMID 28375154 DOI: 10.1172/Jci91816  0.685
2017 Linz BM, Neely CJ, Kartchner LB, Mendoza AE, Khoury AL, Truax A, Sempowski G, Eitas T, Brickey J, Ting JP, Cairns BA, Maile R. Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28159904 DOI: 10.4049/Jimmunol.1601048  0.303
2017 Jha S, Brickey WJ, Ting JP. Inflammasomes in Myeloid Cells: Warriors Within. Microbiology Spectrum. 5. PMID 28102121 DOI: 10.1128/Microbiolspec.Mchd-0049-2016  0.635
2016 Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP. How Mouse Macrophages Sense What Is Going On. Frontiers in Immunology. 7: 204. PMID 27313577 DOI: 10.3389/fimmu.2016.00204  0.366
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Ting JP, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.772
2015 Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, et al. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 126: 1621-8. PMID 26265697 DOI: 10.1182/Blood-2015-03-634691  0.525
2015 Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, ... ... Ting JP, et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nature Medicine. PMID 26107252 DOI: 10.1038/Nm.3908  0.789
2015 Cheong WC, Kang HR, Yoon H, Kang SJ, Ting JP, Song MJ. Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome. Plos One. 10: e0126456. PMID 25978411 DOI: 10.1371/journal.pone.0126456  0.317
2015 Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, et al. Suppression of NLRX1 in chronic obstructive pulmonary disease. The Journal of Clinical Investigation. 125: 2458-62. PMID 25938787 DOI: 10.1172/Jci71747  0.37
2015 O'Brien M, Moehring D, Muñoz-Planillo R, Núñez G, Callaway J, Ting J, Scurria M, Ugo T, Bernad L, Cali J, Lazar D. Abstract 1319: Monitoring inflammasome activation with a bioluminescent caspase-1 assay Cancer Research. 75: 1319-1319. DOI: 10.1158/1538-7445.Am2015-1319  0.376
2014 Rodgers MA, Bowman JW, Fujita H, Orazio N, Shi M, Liang Q, Amatya R, Kelly TJ, Iwai K, Ting J, Jung JU. The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation. The Journal of Experimental Medicine. 211: 1333-47. PMID 24958845 DOI: 10.1084/Jem.20132486  0.391
2014 Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, ... Ting JP, et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41. PMID 24560620 DOI: 10.1016/J.Immuni.2014.01.010  0.606
2013 Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting JP. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. Plos One. 8: e60842. PMID 23577168 DOI: 10.1371/Journal.Pone.0060842  0.644
2013 Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X. Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Reports. 3: 678-88. PMID 23434512 DOI: 10.1016/J.Celrep.2013.01.029  0.407
2013 Lei Y, Wen H, Ting JP. The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy. 9: 432-3. PMID 23321557 DOI: 10.4161/auto.23026  0.472
2013 Roney K, Holl E, Ting J. Immune plexins and semaphorins: old proteins, new immune functions. Protein & Cell. 4: 17-26. PMID 23307780 DOI: 10.1007/S13238-012-2108-4  0.765
2012 Uittenbogaard AM, Chelvarajan RL, Myers-Morales T, Gorman AA, Brickey WJ, Ye Z, Kaplan AM, Cohen DA, Ting JP, Straley SC. Toward a molecular pathogenic pathway for Yersinia pestis YopM. Frontiers in Cellular and Infection Microbiology. 2: 155. PMID 23248776 DOI: 10.3389/Fcimb.2012.00155  0.484
2012 Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH. Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. Plos One. 7: e51105. PMID 23226472 DOI: 10.1371/Journal.Pone.0051105  0.314
2012 Fry RC, Rager JE, Zhou H, Zou B, Brickey JW, Ting J, Lay JC, Peden DB, Alexis NE. Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways. Respiratory Research. 13: 89. PMID 23033980 DOI: 10.1186/1465-9921-13-89  0.344
2012 Holl EK, Roney KE, Allen IC, Steinbach E, Arthur JC, Buntzman A, Plevy S, Frelinger J, Ting JP. Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333. PMID 22916243 DOI: 10.1371/Journal.Pone.0043333  0.793
2012 Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nature Immunology. 13: 823-31. PMID 22863753 DOI: 10.1038/Ni.2378  0.798
2012 Taxman DJ, Swanson KV, Broglie PM, Wen H, Holley-Guthrie E, Huang MT, Callaway JB, Eitas TK, Duncan JA, Ting JP. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. The Journal of Biological Chemistry. 287: 32791-9. PMID 22843689 DOI: 10.1074/Jbc.M112.401737  0.594
2012 Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 488: 670-4. PMID 22801494 DOI: 10.1038/Nature11290  0.314
2012 Kovarova M, Hesker PR, Jania L, Nguyen M, Snouwaert JN, Xiang Z, Lommatzsch SE, Huang MT, Ting JP, Koller BH. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 2006-16. PMID 22753929 DOI: 10.4049/Jimmunol.1201065  0.577
2012 Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, ... ... Ting JP, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity. 36: 933-46. PMID 22749352 DOI: 10.1016/J.Immuni.2012.03.025  0.489
2012 Robbins GR, Truax AD, Davis BK, Zhang L, Brickey WJ, Ting JP. Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins. The Journal of Biological Chemistry. 287: 24294-303. PMID 22645137 DOI: 10.1074/jbc.M112.364604  0.407
2012 Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity. 36: 742-54. PMID 22503542 DOI: 10.1016/J.Immuni.2012.03.012  0.719
2012 Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Analysis of NLRP3 in the development of allergic airway disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 2884-93. PMID 22323538 DOI: 10.4049/Jimmunol.1102488  0.323
2012 Allen IC, Lich JD, Arthur JC, Jania CM, Roberts RA, Callaway JB, Tilley SL, Ting JP. Characterization of NLRP12 during the development of allergic airway disease in mice. Plos One. 7: e30612. PMID 22291998 DOI: 10.1371/Journal.Pone.0030612  0.622
2012 Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP. MyD88 provides a protective role in long-term radiation-induced lung injury. International Journal of Radiation Biology. 88: 335-47. PMID 22248128 DOI: 10.3109/09553002.2012.652723  0.56
2012 Fry R, Zhou H, Zou B, Rager J, Brickey J, Ting J, Peden D, Alexis N. Inflammatory Gene Expression Differentiates With Airway Neutrophil Response To Ozone Journal of Allergy and Clinical Immunology. 129: AB139. DOI: 10.1016/J.Jaci.2011.12.467  0.307
2011 Roney KE, O'Connor BP, Wen H, Holl EK, Guthrie EH, Davis BK, Jones SW, Jha S, Sharek L, Garcia-Mata R, Bear JE, Ting JP. Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. Plos One. 6: e24795. PMID 21966369 DOI: 10.1371/Journal.Pone.0024795  0.808
2011 Barker BR, Taxman DJ, Ting JP. Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. Current Opinion in Immunology. 23: 591-7. PMID 21839623 DOI: 10.1016/J.Coi.2011.07.005  0.807
2011 Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/J.Immuni.2011.03.026  0.815
2011 Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, Lei Y, Gris D, Ting JP. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. The Journal of Biological Chemistry. 286: 19605-16. PMID 21487011 DOI: 10.1074/Jbc.M111.221077  0.797
2011 Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature Immunology. 12: 408-15. PMID 21478880 DOI: 10.1038/Ni.2022  0.731
2011 Holl EK, O'Connor BP, Holl TM, Roney KE, Zimmermann AG, Jha S, Kelsoe G, Ting JP. Plexin-D1 is a novel regulator of germinal centers and humoral immune responses. Journal of Immunology (Baltimore, Md. : 1950). 186: 5603-11. PMID 21464091 DOI: 10.4049/Jimmunol.1003464  0.783
2011 Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B. Discovery of a viral NLR homolog that inhibits the inflammasome. Science (New York, N.Y.). 331: 330-4. PMID 21252346 DOI: 10.1126/Science.1199478  0.3
2011 Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Cutting edge: NLRC5-dependent activation of the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 186: 1333-7. PMID 21191067 DOI: 10.4049/Jimmunol.1003111  0.791
2011 McNally RS, Davis BK, Clements CM, Accavitti-Loper MA, Mak TW, Ting JP. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB. The Journal of Biological Chemistry. 286: 4098-106. PMID 21097510 DOI: 10.1074/Jbc.M110.147371  0.807
2010 van Deventer HW, Burgents JE, Wu QP, Woodford RM, Brickey WJ, Allen IC, McElvania-Tekippe E, Serody JS, Ting JP. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Research. 70: 10161-9. PMID 21159638 DOI: 10.1158/0008-5472.Can-10-1921  0.542
2010 Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP. The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15811-20. PMID 21106820 DOI: 10.1523/Jneurosci.4088-10.2010  0.59
2010 Wen H, Lei Y, Eun SY, Ting JP. Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm. The Journal of Experimental Medicine. 207: 2943-57. PMID 21098092 DOI: 10.1084/jem.20101138  0.66
2010 Huang MT, Mortensen BL, Taxman DJ, Craven RR, Taft-Benz S, Kijek TM, Fuller JR, Davis BK, Allen IC, Brickey WJ, Gris D, Wen H, Kawula TH, Ting JP. Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5476-85. PMID 20921527 DOI: 10.4049/Jimmunol.1002154  0.604
2010 Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, ... Ting JP, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4515-9. PMID 20861349 DOI: 10.4049/Jimmunol.1002227  0.795
2010 McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, Braunstein M, Ting JP. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. Plos One. 5: e12320. PMID 20808838 DOI: 10.1371/Journal.Pone.0012320  0.746
2010 Taxman DJ, Huang MT, Ting JP. Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host & Microbe. 8: 7-11. PMID 20638636 DOI: 10.1016/j.chom.2010.06.005  0.573
2010 Gris D, Ye Z, Iocca HA, Wen H, Craven RR, Gris P, Huang M, Schneider M, Miller SD, Ting JP. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 974-81. PMID 20574004 DOI: 10.4049/Jimmunol.0904145  0.752
2010 Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. The Journal of Experimental Medicine. 207: 1045-56. PMID 20385749 DOI: 10.1084/Jem.20100050  0.666
2010 Ting JP, Duncan JA, Lei Y. How the noninflammasome NLRs function in the innate immune system. Science (New York, N.Y.). 327: 286-90. PMID 20075243 DOI: 10.1126/science.1184004  0.467
2010 Wen H, Lei Y, Eun S, Ting J. Plexin-A4/Semaphorin 3A Signaling is Required for TLR- and Sepsis-induced Cytokine Storm Clinical Immunology. 135: S46. DOI: 10.1016/J.Clim.2010.03.141  0.581
2009 Jha S, Ting JP. Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. Journal of Immunology (Baltimore, Md. : 1950). 183: 7623-9. PMID 20007570 DOI: 10.4049/Jimmunol.0902425  0.579
2009 Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. Plos One. 4: e7446. PMID 19826485 DOI: 10.1371/Journal.Pone.0007446  0.39
2009 Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 2008-15. PMID 19587006 DOI: 10.4049/Jimmunol.0900138  0.806
2009 Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 182: 6460-9. PMID 19414800 DOI: 10.4049/Jimmunol.0802696  0.804
2009 Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated apoptosis and its inhibition by viral proteins. Plos One. 4: e5466. PMID 19404494 DOI: 10.1371/Journal.Pone.0005466  0.723
2009 Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/J.Immuni.2009.02.005  0.636
2009 Lord CA, Savitsky D, Sitcheran R, Calame K, Wright JR, Ting JP, Williams KL. Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1. Journal of Immunology (Baltimore, Md. : 1950). 182: 2948-58. PMID 19234190 DOI: 10.4049/Jimmunol.0801692  0.444
2009 Huang MT, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, Parsons RK, Featherstone GL, Arnold RR, O'Connor BP, Ting JP. Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 2395-404. PMID 19201894 DOI: 10.4049/Jimmunol.0800909  0.754
2008 O'Connor BP, Eun SY, Ye Z, Zozulya AL, Lich JD, Moore CB, Iocca HA, Roney KE, Holl EK, Wu QP, van Deventer HW, Fabry Z, Ting JP. Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 13015-20. PMID 18728195 DOI: 10.1073/Pnas.0803386105  0.791
2008 Willingham SB, Ting JP. NLRs and the dangers of pollution and aging. Nature Immunology. 9: 831-3. PMID 18645588 DOI: 10.1038/ni0808-831  0.56
2008 Li H, Willingham SB, Ting JP, Re F. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. Journal of Immunology (Baltimore, Md. : 1950). 181: 17-21. PMID 18566365  0.675
2008 van Deventer HW, Wu QP, Bergstralh DT, Davis BK, O'Connor BP, Ting JP, Serody JS. C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9. The American Journal of Pathology. 173: 253-64. PMID 18535183 DOI: 10.2353/Ajpath.2008.070732  0.732
2008 Ting JP, Willingham SB, Bergstralh DT. NLRs at the intersection of cell death and immunity. Nature Reviews. Immunology. 8: 372-9. PMID 18362948 DOI: 10.1038/Nri2296  0.809
2008 Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Current Opinion in Immunology. 20: 3-9. PMID 18280719 DOI: 10.1016/J.Coi.2008.01.003  0.545
2008 Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, Ting JP. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. Journal of Neuroimmunology. 194: 97-106. PMID 18207576 DOI: 10.1016/J.Jneuroim.2007.12.003  0.747
2008 Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature. 451: 573-7. PMID 18200010 DOI: 10.1038/Nature06501  0.769
2008 Ye Z, Lich JD, Moore CB, Duncan JA, Williams KL, Ting JP. ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. Molecular and Cellular Biology. 28: 1841-50. PMID 18160710 DOI: 10.1128/Mcb.01468-07  0.523
2007 Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host & Microbe. 2: 147-59. PMID 18005730 DOI: 10.1016/J.Chom.2007.07.009  0.804
2007 Duncan JA, Ting JP. Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome. Cell Host & Microbe. 1: 7-9. PMID 18005676 DOI: 10.1016/j.chom.2007.02.007  0.358
2007 Arthur JC, Lich JD, Aziz RK, Kotb M, Ting JP. Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. Journal of Immunology (Baltimore, Md. : 1950). 179: 6291-6. PMID 17947705 DOI: 10.4049/Jimmunol.179.9.6291  0.632
2007 Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, Ting JP. Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7429-37. PMID 17626203 DOI: 10.1523/Jneurosci.1307-07.2007  0.8
2007 Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 8041-6. PMID 17483456 DOI: 10.1073/Pnas.0611496104  0.796
2007 Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ, Ting JP. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 178: 1256-60. PMID 17237370 DOI: 10.4049/Jimmunol.178.3.1256  0.641
2007 Bergstralh DT, Conti BJ, Moore CB, Brickey WJ, Taxman DJ, Ting JP. Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Experimental Cell Research. 313: 65-76. PMID 17069796 DOI: 10.1016/J.Yexcr.2006.09.016  0.801
2006 Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proceedings of the National Academy of Sciences of the United States of America. 103: 15091-6. PMID 17015834 DOI: 10.1073/Pnas.0607260103  0.78
2006 Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, Ting JP. Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 4271-5. PMID 16982860 DOI: 10.4049/Jimmunol.177.7.4271  0.708
2006 Taxman DJ, Zhang J, Champagne C, Bergstralh DT, Iocca HA, Lich JD, Ting JP. Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 177: 4252-6. PMID 16982856 DOI: 10.4049/Jimmunol.177.7.4252  0.725
2006 Lich JD, Arthur JC, Ting JP. Cryopyrin: in from the cold. Immunity. 24: 241-3. PMID 16546091 DOI: 10.1016/J.Immuni.2006.03.004  0.607
2006 Bergstralh DT, Ting JP. Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treatment Reviews. 32: 166-79. PMID 16527420 DOI: 10.1016/J.Ctrv.2006.01.004  0.655
2006 Taxman DJ, Livingstone LR, Zhang J, Conti BJ, Iocca HA, Williams KL, Lich JD, Ting JP, Reed W. Criteria for effective design, construction, and gene knockdown by shRNA vectors. Bmc Biotechnology. 6: 7. PMID 16433925 DOI: 10.1186/1472-6750-6-7  0.692
2006 Plant SR, Wang Y, Vasseur S, Thrash JC, McMahon EJ, Bergstralh DT, Arnett HA, Miller SD, Carson MJ, Iovanna JL, Ting JP. Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues. Glia. 53: 529-37. PMID 16374777 DOI: 10.1002/Glia.20297  0.773
2005 Zika E, Fauquier L, Vandel L, Ting JP. Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 16321-6. PMID 16254053 DOI: 10.1073/Pnas.0505045102  0.752
2005 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/Jbc.M502820200  0.307
2005 Wang AH, Grégoire S, Zika E, Xiao L, Li CS, Li H, Wright KL, Ting JP, Yang XJ. Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases. The Journal of Biological Chemistry. 280: 29117-27. PMID 15964851 DOI: 10.1074/Jbc.M500295200  0.765
2005 van Deventer HW, O'Connor W, Brickey WJ, Aris RM, Ting JP, Serody JS. C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis. Cancer Research. 65: 3374-9. PMID 15833871 DOI: 10.1158/0008-5472.Can-04-2616  0.695
2005 Conti BJ, Davis BK, Zhang J, O'connor W, Williams KL, Ting JP. CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function. The Journal of Biological Chemistry. 280: 18375-85. PMID 15705585 DOI: 10.1074/Jbc.M413169200  0.795
2005 Zika E, Ting JP. Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Current Opinion in Immunology. 17: 58-64. PMID 15653312 DOI: 10.1016/J.Coi.2004.11.008  0.732
2005 Plant SR, Arnett HA, Ting JP. Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination. Glia. 49: 1-14. PMID 15382206 DOI: 10.1002/Glia.20089  0.785
2005 Ting J. Genomic mining of new genes and pathways in innate and adaptive immunity. Novartis Foundation Symposium. 267: 231-241. DOI: 10.1002/047002139X.Ch15  0.361
2004 Bergstralh DT, Taxman DJ, Chou TC, Danishefsky SJ, Ting JP. A comparison of signaling activities induced by Taxol and desoxyepothilone B. Journal of Chemotherapy (Florence, Italy). 16: 563-76. PMID 15700849 DOI: 10.1179/Joc.2004.16.6.563  0.672
2004 Greer SF, Harton JA, Linhoff MW, Janczak CA, Ting JP, Cressman DE. Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 173: 376-83. PMID 15210796 DOI: 10.4049/Jimmunol.173.1.376  0.726
2004 Arancibia-Cárcamo CV, Osawa H, Arnett HA, Háskova Z, George AJ, Ono SJ, Ting JP, Streilein JW. A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. European Journal of Immunology. 34: 471-80. PMID 14768052 DOI: 10.1002/eji.200324195  0.703
2003 O'Connor W, Harton JA, Zhu X, Linhoff MW, Ting JP. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. Journal of Immunology (Baltimore, Md. : 1950). 171: 6329-33. PMID 14662828 DOI: 10.4049/Jimmunol.171.12.6329  0.805
2003 Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9824-32. PMID 14586011 DOI: 10.1523/Jneurosci.23-30-09824.2003  0.709
2003 MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. Cancer Research. 63: 6928-34. PMID 14583493  0.789
2003 Greer SF, Zika E, Conti B, Zhu XS, Ting JP. Enhancement of CIITA transcriptional function by ubiquitin. Nature Immunology. 4: 1074-82. PMID 14528304 DOI: 10.1038/Ni985  0.785
2003 Taxman DJ, MacKeigan JP, Clements C, Bergstralh DT, Ting JP. Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. Cancer Research. 63: 5095-104. PMID 12941840  0.789
2003 Wong AW, Brickey WJ, Taxman DJ, van Deventer HW, Reed W, Gao JX, Zheng P, Liu Y, Li P, Blum JS, McKinnon KP, Ting JP. CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nature Immunology. 4: 891-8. PMID 12910265 DOI: 10.1038/Ni960  0.58
2003 Williams KL, Taxman DJ, Linhoff MW, Reed W, Ting JP. Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. Journal of Immunology (Baltimore, Md. : 1950). 170: 5354-8. PMID 12759408 DOI: 10.4049/Jimmunol.170.11.5354  0.732
2003 Zika E, Greer SF, Zhu XS, Ting JP. Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. Molecular and Cellular Biology. 23: 3091-102. PMID 12697811 DOI: 10.1128/Mcb.23.9.3091-3102.2003  0.78
2002 Harton JA, Linhoff MW, Zhang J, Ting JP. Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. Journal of Immunology (Baltimore, Md. : 1950). 169: 4088-93. PMID 12370334 DOI: 10.4049/Jimmunol.169.8.4088  0.717
2002 Wong AW, Ghosh N, McKinnon KP, Reed W, Piskurich JF, Wright KL, Ting JP. Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line. Journal of Immunology (Baltimore, Md. : 1950). 169: 3112-9. PMID 12218128 DOI: 10.4049/Jimmunol.169.6.3112  0.609
2002 van Deventer HW, Serody JS, McKinnon KP, Clements C, Brickey WJ, Ting JP. Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. Journal of Immunology (Baltimore, Md. : 1950). 169: 1634-9. PMID 12133994 DOI: 10.4049/Jimmunol.169.3.1634  0.627
2002 MacKeigan JP, Taxman DJ, Hunter D, Earp HS, Graves LM, Ting JP. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2091-9. PMID 12114408  0.749
2002 Harton JA, O'Connor W, Conti BJ, Linhoff MW, Ting JP. Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Human Immunology. 63: 588-601. PMID 12072194 DOI: 10.1016/S0198-8859(02)00400-7  0.789
2002 Arnett HA, Hellendall RP, Matsushima GK, Suzuki K, Laubach VE, Sherman P, Ting JP. The protective role of nitric oxide in a neurotoxicant-induced demyelinating model. Journal of Immunology (Baltimore, Md. : 1950). 168: 427-33. PMID 11751989 DOI: 10.4049/Jimmunol.168.1.427  0.7
2001 Morrison TE, Mauser A, Wong A, Ting JP, Kenney SC. Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early protein. Immunity. 15: 787-99. PMID 11728340 DOI: 10.1016/S1074-7613(01)00226-6  0.603
2001 Arnett HA, Mason J, Marino M, Suzuki K, Matsushima GK, Ting JP. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nature Neuroscience. 4: 1116-22. PMID 11600888 DOI: 10.1038/Nn738  0.671
2001 Zhu XS, Ting JP. A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters. Molecular and Cellular Biology. 21: 7078-88. PMID 11564890 DOI: 10.1128/Mcb.21.20.7078-7088.2001  0.515
2001 Cressman DE, O'Connor WJ, Greer SF, Zhu XS, Ting JP. Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator. Journal of Immunology (Baltimore, Md. : 1950). 167: 3626-34. PMID 11564775 DOI: 10.4049/Jimmunol.167.7.3626  0.464
2001 Harton JA, Zika E, Ting JP. The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator. The Journal of Biological Chemistry. 276: 38715-20. PMID 11514574 DOI: 10.1074/Jbc.M106652200  0.761
2001 Deffrennes V, Vedrenne J, Stolzenberg MC, Piskurich J, Barbieri G, Ting JP, Charron D, Alcaïde-Loridan C. Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B cell-specific promoter. Journal of Immunology (Baltimore, Md. : 1950). 167: 98-106. PMID 11418637 DOI: 10.4049/Jimmunol.167.1.98  0.371
2001 Li G, Harton JA, Zhu X, Ting JP. Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Molecular and Cellular Biology. 21: 4626-35. PMID 11416140 DOI: 10.1128/Mcb.21.14.4626-4635.2001  0.48
2001 Linhoff MW, Harton JA, Cressman DE, Martin BK, Ting JP. Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains. Molecular and Cellular Biology. 21: 3001-11. PMID 11287606 DOI: 10.1128/Mcb.21.9.3001-3011.2001  0.716
2001 Raval A, Howcroft TK, Weissman JD, Kirshner S, Zhu XS, Yokoyama K, Ting J, Singer DS. Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250. Molecular Cell. 7: 105-15. PMID 11172716 DOI: 10.1016/S1097-2765(01)00159-9  0.538
2000 MacKeigan JP, Collins TS, Ting JP. MEK inhibition enhances paclitaxel-induced tumor apoptosis. The Journal of Biological Chemistry. 275: 38953-6. PMID 11038347 DOI: 10.1074/Jbc.C000684200  0.759
2000 Zhu XS, Linhoff MW, Li G, Chin KC, Maity SN, Ting JP. Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter. Molecular and Cellular Biology. 20: 6051-61. PMID 10913187 DOI: 10.1128/Mcb.20.16.6051-6061.2000  0.768
1999 Ting JP, Zhu XS. Class II MHC genes: a model gene regulatory system with great biologic consequences. Microbes and Infection / Institut Pasteur. 1: 855-61. PMID 10614002 DOI: 10.1016/S1286-4579(99)00233-6  0.492
1999 Brickey WJ, Wright KL, Zhu XS, Ting JP. Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor. Journal of Immunology (Baltimore, Md. : 1950). 163: 6622-30. PMID 10586057  0.491
1999 Piskurich JF, Linhoff MW, Wang Y, Ting JP. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Molecular and Cellular Biology. 19: 431-40. PMID 9858567 DOI: 10.1128/MCB.19.1.431  0.729
1998 Hiremath MM, Saito Y, Knapp GW, Ting JP, Suzuki K, Matsushima GK. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. Journal of Neuroimmunology. 92: 38-49. PMID 9916878 DOI: 10.1016/S0165-5728(98)00168-4  0.33
1998 Lee LF, Li G, Templeton DJ, Ting JP. Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK). The Journal of Biological Chemistry. 273: 28253-60. PMID 9774447 DOI: 10.1074/jbc.273.43.28253  0.305
1998 Wright KL, Chin KC, Linhoff M, Skinner C, Brown JA, Boss JM, Stark GR, Ting JP. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 6267-72. PMID 9600954 DOI: 10.1073/Pnas.95.11.6267  0.732
1998 White CM, Martin BK, Lee LF, Haskill JS, Ting JP. Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells. Cancer Immunology, Immunotherapy : Cii. 46: 104-12. PMID 9558006 DOI: 10.1007/S002620050468  0.564
1998 Piskurich JF, Wang Y, Linhoff MW, White LC, Ting JP. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. Journal of Immunology (Baltimore, Md. : 1950). 160: 233-40. PMID 9551976  0.734
1997 Lee LF, Haskill JS, Mukaida N, Matsushima K, Ting JP. Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter. Molecular and Cellular Biology. 17: 5097-105. PMID 9271387 DOI: 10.1128/MCB.17.9.5097  0.303
1997 Linhoff MW, Wright KL, Ting JP. CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model. Molecular and Cellular Biology. 17: 4589-96. PMID 9234716  0.699
1996 Lee LF, Schuerer-Maly CC, Lofquist AK, van Haaften-Day C, Ting JP, White CM, Martin BK, Haskill JS. Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. Cancer Research. 56: 1303-8. PMID 8640818  0.591
1994 Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin AS, Basta PV, Ting JP. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits. Molecular and Cellular Biology. 14: 2926-35. PMID 8164652 DOI: 10.1128/Mcb.14.5.2926  0.714
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  0.524
1992 Panek RB, Moses H, Ting JP, Benveniste EN. Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 11518-22. PMID 1454841 DOI: 10.1073/Pnas.89.23.11518  0.341
1992 Matsushima GK, Itoh-Lindstrom Y, Ting JP. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Molecular and Cellular Biology. 12: 5610-9. PMID 1448091 DOI: 10.1128/mcb.12.12.5610-5619.1992  0.356
1987 Ting JP, Takiguchi M, Macchi M, Frelinger JA. The expression and detection of MHC class I antigens on murine neuroblastoma and ependymoblastoma lines. Journal of Neuroimmunology. 14: 87-98. PMID 3492512 DOI: 10.1016/0165-5728(87)90103-2  0.462
1985 Takiguchi M, Ting JP, Buessow SC, Boyer C, Gillespie Y, Frelinger JA. Response of glioma cells to interferon-gamma: increase in class II RNA, protein and mixed lymphocyte reaction-stimulating ability. European Journal of Immunology. 15: 809-14. PMID 2411569 DOI: 10.1002/Eji.1830150813  0.506
1983 Ting JP, Nixon DF, Weiner LP, Frelinger JA. Brain Ia antigens have a bone marrow origin. Immunogenetics. 17: 295-301. PMID 6572615 DOI: 10.1007/BF00364413  0.43
1982 Nixon DF, Ting JP, Frelinger JA. Ia antigens on non-lymphoid tissues their origins and functions. Immunology Today. 3: 339-42. PMID 25290677 DOI: 10.1016/0167-5699(82)90019-6  0.488
1981 Ting JP, Shigekawa BL, Linthicum DS, Weiner LP, Frelinger JA. Expression and synthesis of murine immune response-associated (Ia) antigens by brain cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 3170-4. PMID 6166944 DOI: 10.1073/pnas.78.5.3170  0.489
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